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3. Germ line ERG haploinsufficiency defines a new syndrome with cytopenia and hematological malignancy predisposition

Author

Baliakas, Panagiotis, Blombery, Piers, Fox, Lucy C., Donadieu, Jean, Rio-Machin, Ana, Steinberg-Shemer, Orna, Morgan, Neil V., Ngeow, Joanne Y. Y., Skokowa, Julia, Pinese, Mark, Cowley, Mark J., Zerella, Jiarna R., Homan, Claire C., Arts, Peer, Lin, Xuzhu, Spinelli, Sam J., Venugopal, Parvathy, Babic, Milena, Brautigan, Peter J., Truong, Lynda, Arriola-Martinez, Luis, Moore, Sarah, Hollins, Rachel, Parker, Wendy T., Nguyen, Hung, Kassahn, Karin S., Branford, Susan, Feurstein, Simone, Larcher, Lise, Sicre de Fontbrune, Flore, Demirdas, Serwet, de Munnik, Sonja, Antoine-Poirel, Hélène, Brichard, Benedicte, Mansour, Sahar, Gordon, Kristiana, Wlodarski, Marcin W., Koppayi, Ashwin, Dobbins, Sara, Mutsaers, Pim G. N. J., Nichols, Kim E., Oak, Ninad, DeMille, Desiree, Mao, Rong, Crawford, Ali, McCarrier, Julie, Basel, Donald, Flores-Daboub, Josue, Drazer, Michael W., Phillips, Kerry, Poplawski, Nicola K., Birdsey, Graeme M., Pirri, Daniela, Ostergaard, Pia, Simons, Annet, Godley, Lucy A., Ross, David M., Hiwase, Devendra K., Soulier, Jean, Brown, Anna L., Carmichael, Catherine L., Scott, Hamish S., and Hahn, Christopher N.

Published
2024
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4. Cognitive-Behavioral Therapy for Insomnia

Author

Hall, Daniel L., Gorman, Mark J., Finkelstein-Fox, Lucy, Wieman, Sarah, Mizrach, Helen, Park, Elyse R., Rosenbaum, Jerrold F., Series Editor, Sprich, Susan E., editor, Petersen, Timothy, editor, and Wilhelm, Sabine, editor

Published
2023
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5. The Australian Aplastic Anaemia and other Bone Marrow Failure Syndromes Registry

Author

Fox, Lucy C., McQuilten, Zoe K., Firkin, Frank, Fox, Vanessa, Badoux, Xavier, Bajel, Ashish, Barbaro, Pasquale, Cole-Sinclair, Merrole F., Forsyth, Cecily, Gibson, John, Hiwase, Devendra K., Johnston, Anna, Mills, Anthony, Roncolato, Fernando, Sutherland, Robyn, Szer, Jeff, Ting, Stephen B., Vilcassim, Shahla, Young, Lauren, Waters, Neil A., and Wood, Erica M.

Published
2023
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6. Somatic mutational landscape of hereditary hematopoietic malignancies caused by germline variants in RUNX1, GATA2, and DDX41

Author

Homan, Claire C., Drazer, Michael W., Yu, Kai, Lawrence, David M., Feng, Jinghua, Arriola-Martinez, Luis, Pozsgai, Matthew J., McNeely, Kelsey E., Ha, Thuong, Venugopal, Parvathy, Arts, Peer, King-Smith, Sarah L., Cheah, Jesse, Armstrong, Mark, Wang, Paul, Bödör, Csaba, Cantor, Alan B., Cazzola, Mario, Degelman, Erin, DiNardo, Courtney D., Duployez, Nicolas, Favier, Remi, Fröhling, Stefan, Rio-Machin, Ana, Klco, Jeffery M., Krämer, Alwin, Kurokawa, Mineo, Lee, Joanne, Malcovati, Luca, Morgan, Neil V., Natsoulis, Georges, Owen, Carolyn, Patel, Keyur P., Preudhomme, Claude, Raslova, Hana, Rienhoff, Hugh, Ripperger, Tim, Schulte, Rachael, Tawana, Kiran, Velloso, Elvira, Yan, Benedict, Kim, Erika, Sood, Raman, Hsu, Amy P., Holland, Steven M., Phillips, Kerry, Poplawski, Nicola K., Babic, Milena, Wei, Andrew H., Forsyth, Cecily, Mar Fan, Helen, Lewis, Ian D., Cooney, Julian, Susman, Rachel, Fox, Lucy C., Blombery, Piers, Singhal, Deepak, Hiwase, Devendra, Phipson, Belinda, Schreiber, Andreas W., Hahn, Christopher N., Scott, Hamish S., Liu, Paul, Godley, Lucy A., and Brown, Anna L.

Published
2023
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12. Standardized practices for RNA diagnostics using clinically accessible specimens reclassifies 75% of putative splicing variants

Author

Abdulrasool, Ghusoon, Akesson, Lauren S., Al Eryani, Ghamdan, Al-Shinnag, Mohammad, Arts, Peer, Bagnall, Richard, Baker, Naomi L., Barnett, Christopher, Beecroft, Sarah, Bennetts, Bruce, Berbic, Marina, Beshay, Victoria, Black, Michael, Blackburn, Jim, Blombery, Piers, Boggs, Kirsten, Bournazos, Adam M., Branford, Susan, Breen, Jimmy, Brown, Natasha J., Bryen, Samantha J., Burnett, Leslie, Canson, Daffodil, Cheong, Pak, Chew, Edward, Chong, Belinda, Christodoulou, John, Chung, Seo-Kyung, Clark, Mike, Cliffe, Corrina, Cole, Melissa, Collins, Felicity, Compton, Alison, Cooper, Antony, Cooper, Sandra T., Corbett, Mark, Cowley, Mark, Davis, Mark R., Delatycki, Martin, Dudding, Tracy, Edwards, Matthew, Eggers, Stefanie, Ewans, Lisa J., Eyras, Eduardo, Faiz, Fathimath, Fernandez, Miriam Fanjul, Fellowes, Andrew, Fennell, Andrew, Field, Michael, Fleischer, Ron, Folland, Chiara, Fox, Lucy, Freckmann, Mary-Louise, Gaff, Clara, Galea, Melanie, Ghaoui, Roula, Goel, Himanshu, Gornanitis, Ilias, Ha, Thuong, Hanna, Bernadette, Harraway, James, Hayashi, Rippei, Hayes, Ian, Henderson, Alex, Hesson, Luke, Heyer, Erin, Hildebrand, Michael, Hipwell, Michael, Ho, Gladys, Horton, Ari E., Hoskins, Cass, Hunter, Matthew F., Jackson, Matilda, James, Paul, Jones, Kristi J., Wong, Justin Jong-Leong, Josephi-Taylor, Sarah, Joshi, Himanshu, Kassahn, Karin, Kaub, Peter, Kevin, Lucy, Kirk, Edwin, Krzesinski, Emma, Kumble, Smitha, Kummerfeld, Sarah, Laing, Nigel, Lau, Chiyan, Lee, Eric, Leighton, Sarah, Lundie, Ben, Lunke, Sebastian, Mallawaarachchi, Amali, Mayoh, Chelsea, McGaughran, Julie, McLean, Alison, McPhillips, Mary, Meldrum, Cliff, Middleton, Edwina, Milnes, Di, Mina, Kym, Mowat, David, Nisselle, Amy, Oates, Emily, Oshlack, Alicia, Palmer, Elizabeth E., Parasivam, Gayathri, Parsons, Michael, Patel, Chirag, Pinner, Jason R., Quinn, Michael, Rasko, John, Ravenscroft, Gina, Ravine, Anja, Recsei, Krista, Regan, Matthew, Rehn, Jacqueline, Riley, Lisa G., Robertson, Stephen, Ronan, Anne, Roscioli, Tony, Ryland, Georgina, Sadedin, Simon, Sandaradura, Sarah A., Schreiber, Andreas, Scott, Hamish, Scott, Rodney, Semsarian, Christopher, Simons, Cas, Singer, Emma, Smith, Janine M., Smyth, Renee, Spurdle, Amanda, Stark, Zornitza, Sullivan, Patricia, Sundercombe, Samantha, Tan, Tiong Y., Tchan, Michel C., Thompson, Bryony A., Thorburn, David, Toubia, John, Trent, Ronald, Tudini, Emma, Voneague, Irina, Waddell, Leigh, Walker, Logan, Wallis, Mathew, Warnock, Nick, Weatheritt, Robert, White, Deborah, White, Susan M., Williams, Mark G., Wilson, Meredith J., Winship, Ingrid, Worgan, Lisa, Wright, Dale C., Wu, Kathy, Yeung, Alison, Ziolowski, Andrew, Bommireddipalli, Shobhana, Ades, Lesley, Alexander, Stephen I., Archibald, Alison D., Balasubramaniam, Shanti, Berman, Yemima, Bojadzieva, Jasmina, Buckley, Michael F., Dawes, Ruebena, Donaldson, Liz, Downie, Lilian, Edwards, Caitlin, Engel, Amanda, Gallacher, Lyndon, Gear, Russell, Goh, Shuxiang, Goodwin, Linda, Higgins, Megan, Hopper, Bruce K., Huq, Aamira J., Kumar, Kishore R., Lemckert, Frances, Leventer, Richard J., Lindsey-Temple, Suzanna E., Ma, Alan, Macaskill, Steven, Marty, Melanie, Marum, Justine E., McCarthy, Hugh J., Menezes, Manoj P., Mohammad, Shekeeb, Niaz, Aram, Patel, Shilpan G., Phelan, Dean, Rajagopalan, Sulekha, Rodgers, Jonathan, Rodrigues, Miriam, Roxburgh, Richard H., Sachdev, Rani, Samarasekera, Ruvishani, Savva, Elena, Schindler, Tim, Shah, Margit, Sinnerbrink, Ingrid B., Smith, Richard J., Springer, Amanda, Strom, Samuel P., Sue, Carolyn M., Tan, Kenneth, Tantsis, Esther, Trainer, Alison H., van Spaendonck-Zwarts, Karin, Walsh, Rebecca, Warwick, Linda, White, Stephanie, Wong, Wui Kwan, Yap, Patrick, and Young, Helen

Published
2022
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13. Study protocol for a hybrid type 1 effectiveness-implementation trial testing virtual tobacco treatment in oncology practices [Smokefree Support Study 2.0]

Author

Goshe, Brett M., Rasmussen, Autumn W., Wagner, Lynne I., Sicks, JoRean D., Gareen, Ilana F., Carlos, Ruth C., Herman, Benjamin A., Walter, Angela Wangari, Regan, Susan, Levy, Douglas E., Mahon, Irene, Muzikansky, Alona, Neil, Jordan M., Lui, Michelle, Dilip, Deepika, Malloy, Laura, Gonzalez, Irina, Finkelstein-Fox, Lucy, McCann, Caitlin, Perez, Elissa, Ostroff, Jamie S., and Park, Elyse R.

Published
2022
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16. Testing the effectiveness of a virtual sustained tobacco treatment: Initial reporting of findings from the EAQ171CD randomized clinical trial conducted by ECOG-ACRIN within the NCI Community Oncology Research Program (NCORP).

Author

Park, Elyse Richelle, Sicks, Jorean D., Goshe, Brett M., Gareen, Ilana F., Herman, Benjamin, Taurone, Alexander, Walter, Angela Wangari, Regan, Susan, Rasmussen, Autumn, Levy, Douglas E., Nicolosi, Gabriella, Muzikansky, Alona, Thompson, Michael A., Lui, Michelle, Malloy, Laura, Gonzalez, Irina, Finkelstein-Fox, Lucy, Carlos, Ruth C., Wagner, Lynne I., and Ostroff, Jamie S.

Published
2024
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19. Erratum to: Utility of clinical comprehensive genomic characterization for diagnostic categorization in patients presenting with hypocellular bone marrow failure syndromes

Author

Blombery, Piers, primary, Fox, Lucy, additional, Ryland, Georgina L., additional, Thompson, Ella R., additional, Lickiss, Jennifer, additional, McBean, Michelle, additional, Yerneni, Satwica, additional, Trainer, Alison, additional, Hughes, David, additional, Greenway, Anthea, additional, Mechinaud, Francoise, additional, Wood, Erica M., additional, Lieschke, Graham J., additional, Szer, Jeff, additional, Barbaro, Pasquale, additional, Roy, John, additional, Wight, Joel, additional, Lynch, Elly, additional, Martyn, Melissa, additional, Gaff, Clara, additional, and Ritchie, David, additional

Published
2024
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20. Mindfulness moderates daily stress and comfort food snacking linkages: a multilevel examination

Author

Finkelstein-Fox, Lucy, Gnall, Katherine E., and Park, Crystal L.

Subjects
Comfort foods -- Psychological aspects, Stress management -- Methods, Mindfulness meditation -- Influence, Psychology and mental health
Abstract

Stress is often associated with poor diet in young adulthood. However, very few studies have examined whether snacking on non-nutritious sweet or salty 'comfort food' is directly linked with daily stress, a common intervention target. Further, trait mindfulness, a psychological resource that may be enhanced by psychological training and regular practice, has yet to be tested as a moderator of daily stress-eating linkages. This 11-day daily diary study examined multilevel linkages between daily stress appraisals and comfort food eating in undergraduates. Daily stress appraisals positively predicted comfort food eating at the between-, but not within-person, level. Mindfulness moderated these effects, such that only more mindful participants demonstrated a negative association between within-person stress and comfort food eating. Results illustrate that chronic stress exposure and acute stress reactivity relate differently to eating behavior. Mindfulness and chronic stress may be key intervention targets for non-clinical groups at risk for unhealthy eating., Author(s): Lucy Finkelstein-Fox [sup.1] , Katherine E. Gnall [sup.1] , Crystal L. Park [sup.1] Author Affiliations: (1) grid.63054.34, 0000 0001 0860 4915, Department of Psychological Sciences, University of Connecticut, , [...]

Published
2020
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21. Unravelling Facets of MECOM-Associated Syndrome: Somatic Genetic Rescue, Clonal Hematopoiesis and Phenotype Expansion

Author

Poli Van Creveldkliniek Medisch, Regenerative Medicine and Stem Cells, Cancer, Genetica Sectie Genoomdiagnostiek, Genetica Klinische Genetica, Child Health, Genetica, Venugopal, Parvathy, Arts, Peer, Fox, Lucy Claire, Simons, Annet, Hiwase, Devendra K, Bardy, Peter G, Narcis, Annette, Ross, David M, van Vulpen, Lize F D, Buijs, Arjan, Bolton, Kelly L, Getta, Bartlomiej, Furlong, Eliska, Carter, Tina, Krapels, Ingrid, Hoeks, Marlijn P A, Al Kindy, Adila, Al Kindy, Farah, de Munnik, Sonja, Evans, Pamela, Frank, Mahalia S B, Bournazos, Adam, Cooper, Sandra T, Ha, Thuong Thi, Jackson, Matilda R, Arriola-Martinez, Luis Alberto, Phillips, Kerry, Brennan, Yvonne, Bakshi, Madhura, Ambler, Karen, Gao, Song, Kassahn, Karin S, Kenyon, Rosalie, Hung, Kevin, Babic, Milena, McGovern, Alan, Rawlings, Lesley, Valkulin, Cassandra, Dejong, Lucas, Fathi, Rema, McRae, Simon, Myles, Nicholas, Ladon, Dariusz, Jongmans, Marjolijn C, Kuiper, Roland P, Poplawski, Nicola, Barbaro, Pasquale M, Blombery, Piers, Brown, Anna L, Hahn, Christopher N, Scott, Hamish S, Poli Van Creveldkliniek Medisch, Regenerative Medicine and Stem Cells, Cancer, Genetica Sectie Genoomdiagnostiek, Genetica Klinische Genetica, Child Health, Genetica, Venugopal, Parvathy, Arts, Peer, Fox, Lucy Claire, Simons, Annet, Hiwase, Devendra K, Bardy, Peter G, Narcis, Annette, Ross, David M, van Vulpen, Lize F D, Buijs, Arjan, Bolton, Kelly L, Getta, Bartlomiej, Furlong, Eliska, Carter, Tina, Krapels, Ingrid, Hoeks, Marlijn P A, Al Kindy, Adila, Al Kindy, Farah, de Munnik, Sonja, Evans, Pamela, Frank, Mahalia S B, Bournazos, Adam, Cooper, Sandra T, Ha, Thuong Thi, Jackson, Matilda R, Arriola-Martinez, Luis Alberto, Phillips, Kerry, Brennan, Yvonne, Bakshi, Madhura, Ambler, Karen, Gao, Song, Kassahn, Karin S, Kenyon, Rosalie, Hung, Kevin, Babic, Milena, McGovern, Alan, Rawlings, Lesley, Valkulin, Cassandra, Dejong, Lucas, Fathi, Rema, McRae, Simon, Myles, Nicholas, Ladon, Dariusz, Jongmans, Marjolijn C, Kuiper, Roland P, Poplawski, Nicola, Barbaro, Pasquale M, Blombery, Piers, Brown, Anna L, Hahn, Christopher N, and Scott, Hamish S

Published
2024

24. The natural history of vascular and other complications in patients treated with nilotinib for chronic myeloid leukemia

Author

Minson, Adrian G., Cummins, Katherine, Fox, Lucy, Costello, Ben, Yeung, David, Cleary, Rebecca, Forsyth, Cecily, Tatarczuch, Maciek, Burbury, Kate, Motorna, Olga, Shortt, Jake, Fleming, Shaun, McQuillan, Andrew, Schwarer, Anthony, Harrup, Rosemary, Holmes, Amy, Ratnasingam, Sumita, Chan, Kah-Lok, Hsu, Wei-Hsun, Ashraf, Asma, Putt, Faye, and Grigg, Andrew

Published
2019
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25. Germ line ERG haploinsufficiency defines a new syndrome with cytopenia and hematological malignancy predisposition

Author

Zerella, Jiarna R., Homan, Claire C., Arts, Peer, Lin, Xuzhu, Spinelli, Sam J., Venugopal, Parvathy, Babic, Milena, Brautigan, Peter J., Truong, Lynda, Arriola-Martinez, Luis, Moore, Sarah, Hollins, Rachel, Parker, Wendy T., Nguyen, Hung, Kassahn, Karin S., Branford, Susan, Feurstein, Simone, Larcher, Lise, Sicre de Fontbrune, Flore, Demirdas, Serwet, de Munnik, Sonja, Antoine-Poirel, Hélène, Brichard, Benedicte, Mansour, Sahar, Gordon, Kristiana, Baliakas, Panagiotis, Blombery, Piers, Fox, Lucy C., Donadieu, Jean, Rio-Machin, Ana, Steinberg-Shemer, Orna, Morgan, Neil V., Ngeow, Joanne Y. Y., Skokowa, Julia, Pinese, Mark, Cowley, Mark J., Wlodarski, Marcin W., Koppayi, Ashwin, Dobbins, Sara, Mutsaers, Pim G. N. J., Nichols, Kim E., Oak, Ninad, DeMille, Desiree, Mao, Rong, Crawford, Ali, McCarrier, Julie, Basel, Donald, Flores-Daboub, Josue, Drazer, Michael W., Phillips, Kerry, Poplawski, Nicola K., Birdsey, Graeme M., Pirri, Daniela, Ostergaard, Pia, Simons, Annet, Godley, Lucy A., Ross, David M., Hiwase, Devendra K., Soulier, Jean, Brown, Anna L., Carmichael, Catherine L., Scott, Hamish S., and Hahn, Christopher N.

Abstract

•Germ line ERG LOF variants predispose to cytopenias and HMs.•Somatic genetic rescue of ERG pathogenic variants in hematopoietic tissues impacts diagnosis, disease severity, and potential for correction.

Published
2024
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26. Efficacy and safety of avatrombopag in combination with immunosuppressive therapy in treatment-naïve and relapsed/refractory severe aplastic anaemia: protocol for the DIAAMOND-Ava-FIRST and DIAAMOND-Ava-NEXT Bayesian Optimal Phase II trials

Author

McQuilten, Zoe, primary, Heritier, Stephane, additional, Fox, Lucy, additional, Fox, Vanessa, additional, Young, Lauren, additional, Blombery, Piers, additional, Cunningham, Ilona, additional, Curnow, Jennifer, additional, Higgins, Alisa, additional, Hiwase, Devendra K, additional, Filshie, Robin, additional, Firkin, Frank, additional, Lacaze, Paul, additional, Mason, Kylie, additional, Mills, Anthony K, additional, Pepperell, Dominic, additional, Patil, Sushrut, additional, Stevenson, William, additional, Szer, Jeff, additional, Waters, Neil, additional, Wilson, Kate, additional, Ting, Stephen, additional, and Wood, Erica, additional

Published
2024
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27. International Forum on Blood Donation in Individuals with Current, Past or Germline Predisposition to Malignancy: Summary

Author

Baggio, Diva, primary, Fox, Lucy C., additional, Wood, Erica M., additional, Aditya, Robby Nur, additional, Goldman, Mindy, additional, van den Berg, Karin, additional, Kayser, Sabine, additional, Wuchter, Patrick, additional, Namba, Noriko, additional, Tsuno, Nelson H., additional, Makino, Shigeyoshi, additional, Lee, Cheuk Kwong, additional, Akhtar, Naim, additional, Shah, Farrukh, additional, Miflin, Gail, additional, Prati, Daniele, additional, La Raja, Massimo, additional, La Rocca, Ursula, additional, Richard, Pascale, additional, Tiberghien, Pierre, additional, Harley, Robert J., additional, Raouf, May Y., additional, Sharma, Ranjita, additional, Kaur, Suminder, additional, Bruijns, Sanne, additional, Prakke‐Weekamp, Henriette, additional, and Dunbar, Nancy, additional

Published
2023
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28. International Forum on Blood Donation in Individuals with Current, Past or Germline Predisposition to Malignancy: Responses

Author

Baggio, Diva, primary, Fox, Lucy C., additional, Wood, Erica M., additional, Aditya, Robby Nur, additional, Goldman, Mindy, additional, van den Berg, Karin, additional, Kayser, Sabine, additional, Wuchter, Patrick, additional, Namba, Noriko, additional, Tsuno, Nelson H., additional, Makino, Shigeyoshi, additional, Lee, Cheuk Kwong, additional, Akhtar, Naim, additional, Shah, Farrukh, additional, Miflin, Gail, additional, Prati, Daniele, additional, La Raja, Massimo, additional, Rocca, Ursula La, additional, Richard, Pascale, additional, Tiberghien, Pierre, additional, Harley, Robert J., additional, Raouf, May Y., additional, Sharma, Ranjita, additional, Kaur, Suminder, additional, Bruijns, Sanne, additional, Prakke‐Weekamp, Henriette, additional, and Dunbar, Nancy, additional

Published
2023
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29. Unraveling facets of MECOM-associated syndrome: somatic genetic rescue, clonal hematopoiesis, and phenotype expansion

Author

Venugopal, Parvathy, Arts, Peer, Fox, Lucy C., Simons, Annet, Hiwase, Devendra K., Bardy, Peter G., Swift, Annette, Ross, David M., van Vulpen, Lize F. D., Buijs, Arjan, Bolton, Kelly L., Getta, Bartlomiej, Furlong, Eliska, Carter, Tina, Krapels, Ingrid, Hoeks, Marlijn, Al Kindy, Adila, Al Kindy, Farah, de Munnik, Sonja, Evans, Pamela, Frank, Mahalia S. B., Bournazos, Adam M., Cooper, Sandra T., Ha, Thuong Thi, Jackson, Matilda R., Arriola-Martinez, Luis, Phillips, Kerry, Brennan, Yvonne, Bakshi, Madhura, Ambler, Karen, Gao, Song, Kassahn, Karin S., Kenyon, Rosalie, Hung, Kevin, Babic, Milena, McGovern, Alan, Rawlings, Lesley, Vakulin, Cassandra, Dejong, Lucas, Fathi, Rema, McRae, Simon, Myles, Nicholas, Ladon, Dariusz, Jongmans, Marjolijn, Kuiper, Roland P., Poplawski, Nicola K., Barbaro, Pasquale, Blombery, Piers, Brown, Anna L., Hahn, Christopher N., and Scott, Hamish S.

Published
2024
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32. S176: FUNCTIONAL AND ANTIGEN-SPECIFIC CHARACTERIZATION OF IMMUNE CELLS AT THE SINGLE-CELL LEVEL REVEALS CONVERGENCE OF ADAPTIVE AND INNATE IMMUNITY IN IMMUNE APLASTIC ANEMIA

Author

Huuhtanen, Jani, primary, Lundgren, Sofie, additional, Keränen, Mikko, additional, Feng, Xingim, additional, Dulau-Florea, Alina, additional, Patel, Bhavisha, additional, Zaimoku, Yoshitaka, additional, Kerr, Cassandra, additional, Jokinen, Emmi, additional, Heinonen, Markus, additional, Rajala, Hanna, additional, Siitonen, Sanna, additional, Ebeling, Freja, additional, Ryland, Georgina, additional, Fox, Lucy, additional, Blombery, Piers, additional, Hellström-Lindberg, Eva, additional, Maciejewski, Jaroslaw P., additional, Young, Neal S., additional, Lähdesmäki, Harri, additional, and Mustjoki, Satu, additional

Published
2023
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33. The incidence and natural history of dasatinib complications in the treatment of chronic myeloid leukemia

Author

Fox, Lucy C., Cummins, Katherine D., Costello, Ben, Yeung, David, Cleary, Rebecca, Forsyth, Cecily, Tatarczuch, Maciek, Burbury, Kate, Motorna, Olga, Shortt, Jake, Fleming, Shaun, McQuillan, Andrew, Schwarer, Anthony, Harrup, Rosemary, Holmes, Amy, Ratnasingam, Sumita, Chan, Kah-Lok, Hsu, Wei-Hsun, Ashraf, Asma, Putt, Faye, and Grigg, Andrew

Published
2017
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34. Disruptions in self‐regulatory processes predict depression and sleep disturbance in bereaved young adults.

Author

Finkelstein‐Fox, Lucy, Park, Crystal L., Eigsti, Inge‐Marie, Awao, Sayaka, and Mancini, Anthony D.

Subjects
*RESEARCH funding, *SELF-control, *BEREAVEMENT, *LONGITUDINAL method, *PSYCHOLOGICAL stress, *RESEARCH, *MENTAL depression, *SLEEP disorders, *COGNITION
Abstract

Losing a loved one is both common and profoundly stressful for young adults. Little research has examined the longitudinal course of post‐loss cognitive processing, depression, and sleep difficulties. Further, little is known about the context of other stressors or the role of individual regulatory resources, such as attentional regulation, that might determine whether loss‐related cognitive processing reduces distress. This prospective study examined changes in depression and sleep disturbance over 9 weeks as a function of within‐ and between‐person variation in stress exposure, loss‐related cognitive processing, and attention regulation. Participants were 108 recently bereaved college students completing a lab‐based assessment of attention regulation and four self‐report surveys, spaced three weeks apart. Results revealed that most participants gradually reduced loss‐related processing over the study period, with corresponding improvements in depression and sleep. Stress exposure was associated with increased processing, depression, and sleep disturbance. In exploratory analyses, high attentional alertness and slow re‐orienting strengthened the association of within‐person loss processing with sleep disturbance. Both within‐ and between‐person variation in stress appear to engender risk for a prolonged course of bereavement. Future research should integrate objective attention measures with self‐reported adjustment to stress to illuminate reciprocal links between depression, sleep, and loss‐related cognitive processing. [ABSTRACT FROM AUTHOR]

Published
2024
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35. Effects of Sexual and Gender Minority Stress on Depressive Symptoms Among Adolescents of Color in the United States.

Author

Ching, Terence H. W., Finkelstein-Fox, Lucy, Lee, Sharon Y., and Watson, Ryan J.

Subjects
*SEXUAL minorities, *MINORITY stress, *MENTAL depression, *MICROAGGRESSIONS, *STRUCTURAL equation modeling, *TEENAGERS, *SOCIAL stigma
Abstract

Objective: There is a need for more research on minority stress theory (MST) with sexual and gender minority (SGM) adolescents of color, because of their disproportionate risk for depression. Method: We recruited 1,627 SGM adolescents of color in the United States to complete measures assessing lesbian, gay, bisexual, transgender, and queer (LGBTQ) climate, LGBTQ microaggressions within one's ethnoracial community, internalized LGBTQ stigma, stress management ability, and depressive symptoms. Using structural equation modeling, a hybrid measurement-structural model was tested, indicating good model fit. Results: Multiple significant indirect pathways linking LGBTQ climate and depressive symptoms emerged. A less positive LGBTQ climate was associated with more microaggression-related stress, more internalized LGBTQ stigma, and worse stress management ability, all of which were associated with greater depressive symptoms. A serial mediation with more microaggression-related stress being associated with greater internalized LGBTQ stigma approached significance. Conclusions: Our findings generally support MST processes in terms of depressive symptoms in SGM adolescents of color, suggesting that psychosocial interventions targeting these processes may have meaningful implications for the mental health of this vulnerable group. Public Significance Statement: The stress related to being LGBTQ can contribute to risk of depression among adolescents of color. This study showed that the stressors of an unsupportive climate, as well as anti-LGBTQ sentiments from adolescents' own ethnoracial community, are directly and indirectly linked to depressive symptoms, through the internalization of stigma about being LGBTQ and poor stress management ability. [ABSTRACT FROM AUTHOR]

Published
2024
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37. Integrating genomics into diagnostic and management strategies for patients with Bone Marrow Failure Syndromes

Author

Fox, Lucy Claire Buchanan and Fox, Lucy Claire Buchanan

Abstract

The bone marrow failure syndromes (BMFS) are a heterogeneous group of diseases with differing underlying pathogenic processes and treatment approaches. Diagnosis remains challenging as these conditions can mimic each other, both in clinical presentation, on morphological examination of the bone marrow and their shared potential to transform to haematological malignancy. The BMFS are associated with poor outcomes and there remain many gains to be made in improving both diagnostic and treatment strategies. Both comprehensive clinical data interrogation and genomic analysis by next generation sequencing (NGS) were employed in an effort to examine the clinical, genomic and molecular determinants of outcome in patients with BMFS. The focus of this thesis was to integrate genomics into diagnostic and management strategies to improve outcomes for patients with BMFS. Initially, the utility of comprehensive genomic sequencing to attain accurate diagnosis in patients presenting with bone marrow failure (BMF) was analysed. This work was a prospective demonstration evaluation study. The observed utility of germline and somatic genetic testing in patients presenting with hypocellular BMF and hereditary predisposition to haematological malignancy (HPHM) led to availability of clinical accredited BMF testing, the uptake and outcomes of which were then analysed in the real world setting. The comprehensive dataset of the Australian Aplastic Anaemia and other Bone Marrow Failure Syndromes Registry (the AAR) was interrogated to examine the treatments applied in and outcomes of patients with immune aplastic anaemia (iAA). The AAR was modernised to facilitate enrolment of patients with both traditional inherited BMF (IBMF) and also novel germline conditions, including those recently discovered and described as conferring a HPHM. Consideration of whether a HPHM exists is now considered to represent a crucial component of new leukaemia diagnostic work up. The AAR provides an opportunity t

Published
2023

41. Detection of Novel Occult Germline Multi-Exon Deletions in Patients with DDX41 Familial Predisposition to Myeloid Malignancy

Author

Maierhofer, Anna, primary, Fox, Lucy C, additional, Hutter, Stephan, additional, Baer, Constance, additional, Thompson, Ella, additional, Nguyen, Tamia, additional, Den Elzen, Nicole, additional, Filshie, Robin J, additional, Tiong, Ing S, additional, Nadarajah, Niroshan, additional, Meggendorfer, Manja, additional, Kern, Wolfgang, additional, Haferlach, Claudia, additional, Haferlach, Torsten, additional, and Blombery, Piers, additional

Published
2022
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42. Efficacy and Safety of Avatrombopag in Combination with Immunosuppressive Therapy in Treatment-Naïve and Relapsed/Refractory Severe Aplastic Anaemia - the Diaamond-Ava-First and Diaamond-Ava-Next Bayesian Optimal Phase II Trials

Author

McQuilten, Zoe, primary, Fox, Lucy C, additional, Fox, Vanessa, additional, Heritier, Stephane, additional, Batt, Tracey J, additional, Blombery, Piers, additional, Curnow, Jennifer, additional, Higgins, Alisa, additional, Hiwase, Devendra, additional, Filshie, Robin J, additional, Firkin, Frank, additional, Lacaze, Paul, additional, Mason, Kylie D, additional, Mills, Tony, additional, Patil, Sushrut S., additional, Pepperell, Dominic, additional, Stevenson, William S, additional, Szer, Jeffrey, additional, Waters, Neil, additional, Wilson, Kate, additional, Ting, Stephen B, additional, and Wood, Erica M., additional

Published
2022
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43. Somatic Mutational Landscape of Hereditary Hematopoietic Malignancies Associated with Germline Variants in RUNX1, GATA2 and DDX41

Author

Brown, Anna L., primary, Homan, Claire, additional, Drazer, Michael W., additional, Yu, Kai, additional, Lawrence, David, additional, Feng, Jinghua, additional, Arriola-Martinez, Luis, additional, Pozsgai, Matthew, additional, McNeely, Kelsey, additional, Ha, Thuong, additional, Venugopal, Parvathy, additional, Arts, Peer, additional, King-Smith, Sarah, additional, Cheah, Jesse JC, additional, Armstrong, Mark, additional, Bödör, Csaba, additional, Wang, Paul, additional, Cantor, Alan B., additional, Cazzola, Mario, additional, Degelman, Erin, additional, DiNardo, Courtney D., additional, Duployez, Nicolas, additional, Favier, Remi, additional, Fröhling, Stefan, additional, Rio-Machin, Ana, additional, Klco, Jeffery M., additional, Krämer, Alwin, additional, Kurokawa, Mineo, additional, Lee, Joanne, additional, Malcovati, Luca, additional, Morgan, Neil V, additional, Natsoulis, Georges, additional, Owen, Carolyn, additional, Patel, Keyur P., additional, Preudhomme, Claude, additional, Raslova, Hana, additional, Rienhoff, Hugh Young, additional, Ripperger, Tim, additional, Schulte, Rachael, additional, Tawana, Kiran, additional, Velloso, Elvira Deolinda Rodrigues Pereira, additional, Yan, Benedict, additional, Sood, Raman, additional, Hsu, Amy, additional, Holland, Steven M., additional, Phillips, Kerry, additional, Poplawski, Nicola, additional, Babic, Milena, additional, Kwon Kim, Erika M, additional, Wei, Andrew H., additional, Forsyth, Cecily, additional, Mar Fan, Helen, additional, Lewis, Ian D, additional, Cooney, Julian, additional, Susman, Rachel, additional, Fox, Lucy C, additional, Blombery, Piers, additional, Singhal, Deepak, additional, Hiwase, Devendra, additional, Schreiber, Andreas W, additional, Hahn, Christopher N, additional, Scott, Hamish S, additional, Liu, Paul P., additional, and Godley, Lucy A., additional

Published
2022
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