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17 results on '"Fours, Baptiste"'

6. Rimonabant n-methylpyrrolidone solvate, method for preparing same and pharmaceutical compositions containing same

Author

Coquerel, Gérard, Fours, Baptiste, Sciences et Méthodes Séparatives (SMS), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU), and Lemercier, Aurélien

Subjects
[CHIM.MATE] Chemical Sciences/Material chemistry, [CHIM.ORGA]Chemical Sciences/Organic chemistry, [CHIM.CRIS]Chemical Sciences/Cristallography, [CHIM.MATE]Chemical Sciences/Material chemistry, [CHIM.CRIS] Chemical Sciences/Cristallography, [CHIM.ORGA] Chemical Sciences/Organic chemistry
Published
2007

7. Rimonabant 2-methoxyethanol solvate and method for preparing same

Author

Coquerel, Gérard, Fours, Baptiste, Sciences et Méthodes Séparatives (SMS), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU), and Lemercier, Aurélien

Subjects
[CHIM.MATE] Chemical Sciences/Material chemistry, [CHIM.ORGA]Chemical Sciences/Organic chemistry, [CHIM.CRIS]Chemical Sciences/Cristallography, [CHIM.MATE]Chemical Sciences/Material chemistry, [CHIM.CRIS] Chemical Sciences/Cristallography, [CHIM.ORGA] Chemical Sciences/Organic chemistry
Abstract

The invention relates to a rimonabant 2-methoxyethanol solvate, and to a method for preparing the same.Classifications

Published
2007

8. Rimonabant dmso solvate, method for preparing same and pharmaceutical compositions containing same

Author

Coquerel, Gerard, Fours, Baptiste, Sciences et Méthodes Séparatives (SMS), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU), and Lemercier, Aurélien

Subjects
[CHIM.MATE] Chemical Sciences/Material chemistry, [CHIM.ORGA]Chemical Sciences/Organic chemistry, [CHIM.CRIS]Chemical Sciences/Cristallography, [CHIM.MATE]Chemical Sciences/Material chemistry, [CHIM.CRIS] Chemical Sciences/Cristallography, [CHIM.ORGA] Chemical Sciences/Organic chemistry
Abstract

The invention relates to a rimonabant DMSO solvate, to a method for preparing the same and to the therapeutic uses thereof.

Published
2007

9. 3-methylbutan-1-ol solvate of rimonabant, preparation method thereof and pharmaceutical compositions containing same

Author

Coquerel, Gérard, Fours, Baptiste, Sciences et Méthodes Séparatives (SMS), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU), and Lemercier, Aurélien

Subjects
[CHIM.MATE] Chemical Sciences/Material chemistry, [CHIM.ORGA]Chemical Sciences/Organic chemistry, [CHIM.CRIS]Chemical Sciences/Cristallography, [CHIM.MATE]Chemical Sciences/Material chemistry, [CHIM.CRIS] Chemical Sciences/Cristallography, [CHIM.ORGA] Chemical Sciences/Organic chemistry
Abstract

The invention relates to 3-methylbutan-1-ol solvate of rimonabant, preparation method thereof and therapeutic use of same.

Published
2007

10. Rimonabant 1,4-dioxane solvate, method for preparing same and pharmaceutical compositions containing same: The invention relates to a rimonabant 1,4-dioxane solvate, to a method for preparing the same and to the therapeutic uses thereof

Author

Coquerel, Gérard, Fours, Baptiste, Sciences et Méthodes Séparatives (SMS), Université de Rouen Normandie (UNIROUEN), and Normandie Université (NU)-Normandie Université (NU)

Subjects
[CHIM.ORGA]Chemical Sciences/Organic chemistry, [CHIM.CRIS]Chemical Sciences/Cristallography, [CHIM.MATE]Chemical Sciences/Material chemistry
Published
2007

11. Rimonabant n,n-dimethylformamide solvate, and method for preparing same

Author

Coquerel, Gérard, Fours, Baptiste, Lemercier, Aurélien, Sciences et Méthodes Séparatives (SMS), Université de Rouen Normandie (UNIROUEN), and Normandie Université (NU)-Normandie Université (NU)

Subjects
[CHIM.MATE] Chemical Sciences/Material chemistry, [CHIM.ORGA]Chemical Sciences/Organic chemistry, [CHIM.CRIS]Chemical Sciences/Cristallography, [CHIM.MATE]Chemical Sciences/Material chemistry, [CHIM.CRIS] Chemical Sciences/Cristallography, [CHIM.ORGA] Chemical Sciences/Organic chemistry
Abstract

The invention relates to a rimonabant N,N-dimethylformamide solvate, and to a method for preparing the same.

Published
2007

13. Isopropanol solvate of rimonabant, preparation method thereof and pharmaceutical compositions containing same

Author

Coquerel, Gérard, Fours, Baptiste, Lemercier, Aurélien, Sciences et Méthodes Séparatives (SMS), Université de Rouen Normandie (UNIROUEN), and Normandie Université (NU)-Normandie Université (NU)

Subjects
[CHIM.MATE] Chemical Sciences/Material chemistry, [CHIM.ORGA]Chemical Sciences/Organic chemistry, [CHIM.CRIS]Chemical Sciences/Cristallography, [CHIM.MATE]Chemical Sciences/Material chemistry, [CHIM.CRIS] Chemical Sciences/Cristallography, [CHIM.ORGA] Chemical Sciences/Organic chemistry
Published
2007

14. Rimonabant monohydrate, process for the preparation thereof and pharmaceutical compositions containing same

Author

Monnier, Olivier, Coquerel, Gérard, Fours, Baptiste, DUPLAA, Hélène, Ochsenbein, Philippe, Lemercier, Aurélien, Sciences et Méthodes Séparatives (SMS), Université de Rouen Normandie (UNIROUEN), and Normandie Université (NU)-Normandie Université (NU)

Subjects
[CHIM.MATE] Chemical Sciences/Material chemistry, [CHIM.ORGA]Chemical Sciences/Organic chemistry, [CHIM.CRIS]Chemical Sciences/Cristallography, [CHIM.MATE]Chemical Sciences/Material chemistry, [CHIM.CRIS] Chemical Sciences/Cristallography, [CHIM.ORGA] Chemical Sciences/Organic chemistry
Abstract

The present invention relates to rimonabant monohydrate, to the process for preparing it and to the pharmaceutical compositions containing it.

Published
2006

16. Ionic co-crystals of racetams: solid-state properties enhancement of neutral active pharmaceutical ingredients via addition of Mg2+ and Ca2+ chlorides.

Author

Grepioni, Fabrizia, Wouters, Johan, Braga, Dario, Nanna, Saverio, Fours, Baptiste, Coquerel, Gérard, Longfils, Geraldine, Rome, Sandrine, Aerts, Luc, and Quéré, Luc

Subjects
ANTICONVULSANTS, PHARMACEUTICAL chemistry, CHLORIDES, CRYSTAL structure research, X-ray diffraction
Abstract

Mechanochemical and solution based reactions of solid brivaracetam (BRV) and seletracetam (SEL), antiepileptic drugs from UCB's pipeline, with the inorganic salts MgCl2 and CaCl2, yield ionic co-crystals with changed or improved physico-chemical properties with respect to pure drugs (melting point, hygroscopicity, crystal morphology). All co-crystals are characterized a combination of solid-state techniques, single crystal and powder X-ray diffraction, variable temperature X-ray diffraction, DSC, TGA and hot-stage microscopy (HSM). [ABSTRACT FROM AUTHOR]

Published
2014
Full Text
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17. Ionic co-crystals of racetams: solid-state properties enhancement of neutral active pharmaceutical ingredients via addition of Mg2+ and Ca2+ chlorides

Author

Fabrizia Grepioni, Luc Quere, Gérard Coquerel, Geraldine Longfils, Sandrine Rome, Luc Aerts, Johan Wouters, Dario Braga, Saverio Nanna, Baptiste Fours, Grepioni, Fabrizia, Wouters, Johan, Braga, Dario, Nanna, Saverio, Fours, Baptiste, Coquerel, Gérard, Longfils, Geraldine, Rome, Sandrine, Aerts, Luc, Quéré, Luc, Sciences et Méthodes Séparatives (SMS), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU), and UCB Pharma S.A.[Braine-l'Alleud]

Subjects
Diffraction, Active ingredient, [CHIM.ORGA]Chemical Sciences/Organic chemistry, Chemistry, Inorganic chemistry, Ionic bonding, [CHIM.MATE]Chemical Sciences/Material chemistry, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, General Chemistry, Condensed Matter Physics, Crystal engineering, Crystal engineering, pharmaceutical co-crystals, crystallography, Seletracetam, Yield (chemistry), [CHIM.CRIS]Chemical Sciences/Cristallography, Melting point, medicine, [CHIM]Chemical Sciences, General Materials Science, Single crystal, ComputingMilieux_MISCELLANEOUS, medicine.drug
Abstract

Mechanochemical and solution based reactions of solid brivaracetam (BRV) and seletracetam (SEL), antiepileptic drugs from UCB's pipeline, with the inorganic salts MgCl2 and CaCl2, yield ionic co-crystals with changed or improved physico-chemical properties with respect to pure drugs (melting point, hygroscopicity, crystal morphology). All co-crystals are characterized via a combination of solid-state techniques, i.e. single crystal and powder X-ray diffraction, variable temperature X-ray diffraction, DSC, TGA and hot-stage microscopy (HSM).

Published
2014
Full Text
View/download PDF

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