212 results on '"Fothergill-Gilmore, Linda A."'
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2. M2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation
3. Protein Fragmentation
4. Peptide Sequence Determination
5. Recombinant Protein Technology
6. Design, synthesis and trypanocidal activity of lead compounds based on inhibitors of parasite glycolysis
7. Pyruvate kinase from Plasmodium falciparum: Structural and kinetic insights into the allosteric mechanism
8. The Phosphoglycerate Mutases
9. Structures of Leishmania Fructose-1,6-Bisphosphatase Reveal Species-Specific Differences in the Mechanism of Allosteric Inhibition
10. Higher-plant cofactor-independent phosphoglyceromutase: purification, molecular characterization and expression
11. Characterization of the cofactor-independent phosphoglycerate mutase from Leishmania mexicana mexicana: Histidines that coordinate the two metal ions in the active site show different susceptibilities to irreversible chemical modification
12. The active site architecture of a short-chain dehydrogenase defined by site-directed mutagenesis and structure modeling
13. An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor
14. Pyruvate Kinase Regulates the Pentose-Phosphate Pathway in Response to Hypoxia in Mycobacterium tuberculosis
15. Backbone assignment of double labelled 23.7 kDa phosphoglycerate mutase from Schizosaccharomyces pombe
16. Glycolysis as a target for the design of new anti-trypanosome drugs
17. An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor
18. Allosteric pyruvate kinase-based “logic gate” synergistically senses energy and sugar levels in Mycobacterium tuberculosis
19. Glycolytic Enzymes
20. Regional chromosomal assignment of the human platelet phosphofructokinase gene to 10p15
21. An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor.
22. Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis.
23. Structures of pyruvate kinases display evolutionarily divergent allosteric strategies
24. Trypanosomatid phosphoglycerate mutases have multiple conformational and oligomeric states
25. Pyruvate kinases have an intrinsic and conserved decarboxylase activity
26. Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase
27. Characterisation of active-site mutants of Schizosaccharomyces pombe phosphoglycerate mutase
28. `In crystallo' substrate binding triggers major domain movements and reveals magnesium as a co-activator ofTrypanosoma bruceipyruvate kinase
29. A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinase
30. The Trypanocidal Drug Suramin and Other Trypan Blue Mimetics Are Inhibitors of Pyruvate Kinases and Bind to the Adenosine Site
31. Phosphoglycerate mutase from Trypanosoma brucei is hyperactivated by cobalt in vitro, but not in vivo
32. Allosteric Mechanism of Pyruvate Kinase from Leishmania mexicana Uses a Rock and Lock Model
33. Glycolytic Enzymes
34. An improved strategy for the crystallization ofLeishmania mexicanapyruvate kinase
35. Crystal Structures of Leishmania mexicana Phosphoglycerate Mutase Suggest a One-Metal Mechanism and a New Enzyme Subclass
36. The Crystal Structure of ATP-bound Phosphofructokinase from Trypanosoma brucei Reveals Conformational Transitions Different from those of Other Phosphofructokinases
37. Sulphate Removal Induces a Major Conformational Change in Leishmania mexicana Pyruvate Kinase in the Crystalline State
38. The First Crystal Structure of Phosphofructokinase from a Eukaryote: Trypanosoma brucei
39. An endochitinase A from Vibrio carchariae: cloning, expression, mass and sequence analyses, and chitin hydrolysis
40. Expression, purification, crystallization and preliminary crystallographic analysis ofLeishmania mexicanaphosphoglycerate mutase
41. Expression, purification, crystallization and preliminary crystallographic analysis ofTrypanosoma bruceiphosphofructokinase
42. Crystal Structure of a Thermostable Lipase from Bacillus stearothermophilus P1
43. The putative effector-binding site ofLeishmania mexicanapyruvate kinase studied by site-directed mutagenesis
44. Expression, purification, crystallization and preliminary crystallographic analysis of a thermostable lipase fromBacillus stearothermophilusP1
45. Solution structure and dynamics of an open β-sheet, glycolytic enzyme, monomeric 23.7 kDa phosphoglycerate mutase from Schizosaccharomyces pombe11Edited by M. F. Summers
46. Characterization of active-site mutants ofSchizosaccharomyces pombephosphoglycerate mutase
47. Protein biotechnology: a BioUpdate Foundation post-experience course
48. Poly(ADP-ribosylation) protects maternally derived histones from proteolysis after fertilization
49. The structure of pyruvate kinase from Leishmania mexicana reveals details of the allosteric transition and unusual effector specificity
50. Polyanionic Inhibitors of Phosphoglycerate Mutase: Combined Structural and Biochemical Analysis
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