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2. Survival of male genital cancers (prostate, testis and penis) in Europe 1999–2007: Results from the EUROCARE-5 study

Author

Hackl, M., Zielonke, N., Oberaigner, W., Van Eycken, E., Henau, K., Valerianova, Z., Dimitrova, N., Sekerija, M., Zvolský, M., Dušek, L., Storm, H., Engholm, G., Mägi, M., Aareleid, T., Malila, N., Seppä, K., Velten, M., Troussard, X., Bouvier, V., Launoy, G., Guizard, A.V., Faivre, J., Bouvier, A.M., Arveux, P., Maynadié, M., Woronoff, A.S., Robaszkiewicz, M., Baldi, I., Monnereau, A., Tretarre, B., Bossard, N., Belot, A., Colonna, M., Molinié, F., Bara, S., Schvartz, C., Lapôtre-Ledoux, B., Grosclaude, P., Meyer, M., Stabenow, R., Luttmann, S., Eberle, A., Brenner, H., Nennecke, A., Engel, J., Schubert-Fritschle, G., Kieschke, J., Heidrich, J., Holleczek, B., Katalinic, A., Jónasson, J.G., Tryggvadóttir, L., Comber, H., Mazzoleni, G., Bulatko, A., Buzzoni, C., Giacomin, A., Sutera Sardo, A., Mancuso, P., Ferretti, S., Crocetti, E., Caldarella, A., Gatta, G., Sant, M., Amash, H., Amati, C., Baili, P., Berrino, F., Bonfarnuzzo, S., Botta, L., Di Salvo, F., Foschi, R., Margutti, C., Meneghini, E., Minicozzi, P., Trama, A., Serraino, D., Dal Maso, L., De Angelis, R., Caldora, M., Capocaccia, R., Carrani, E., Francisci, S., Mallone, S., Pierannunzio, D., Roazzi, P., Rossi, S., Santaquilani, M., Tavilla, A., Pannozzo, F., Busco, S., Bonelli, L., Vercelli, M., Gennaro, V., Ricci, P., Autelitano, M., Randi, G., Ponz De Leon, M., Marchesi, C., Cirilli, C., Fusco, M., F. Vitale, M., Usala, M., Traina, A., Staiti, R., Vitale, F., Ravazzolo, B., Michiara, M., Tumino, R., Giorgi Rossi, P., Di Felice, E., Falcini, F., Iannelli, A., Sechi, O., Cesaraccio, R., Piffer, S., Madeddu, A., Tisano, F., Maspero, S., Fanetti, A.C., Zanetti, R., Rosso, S., Candela, P., Scuderi, T., Stracci, F., Bianconi, F., Tagliabue, G., Contiero, P., Dei Tos, A.P., Guzzinati, S., Pildava, S., Smailyte, G., Calleja, N., Agius, D., Johannesen, T.B., Rachtan, J., Gózdz, S., Mezyk, R., Blaszczyk, J., Bebenek, M., Bielska-Lasota, M., Forjaz de Lacerda, G., Bento, M.J., Castro, C., Miranda, A., Mayer-da-Silva, A., Nicula, F., Coza, D., Safaei Diba, C., Primic-Zakelj, M., Almar, E., Ramírez, C., Errezola, M., Bidaurrazaga, J., Torrella-Ramos, A., Díaz García, J.M., Jimenez-Chillaron, R., Marcos-Gragera, R., Izquierdo Font, A., J. Sanchez, M., Chang, D.Y.L., Navarro, C., Chirlaque, M.D., Moreno-Iribas, C., Ardanaz, E., Galceran, J., Carulla, M., Lambe, M., Khan, S., Mousavi, M., Bouchardy, C., Usel, M., M. Ess, S., Frick, H., Lorez, M., Ess, S.M., Herrmann, C., Bordoni, A., Spitale, A., Konzelmann, I., Visser, O., Verhoeven, R., Coleman, M., Allemani, C., Rachet, B., Verne, J., Easey, N., Lawrence, G., Moran, T., Rashbass, J., Roche, M., Wilkinson, J., Gavin, A., Donnelly, C., Brewster, D.H., Huws, D.W., White, C., Otter, R., Trama, Annalisa, Foschi, Roberto, Larrañaga, Nerea, Sant, Milena, Fuentes-Raspall, Rafael, Serraino, Diego, Tavilla, Andrea, Van Eycken, Liesbet, and Nicolai, Nicola

Published
2015
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14. Estimates of cancer burden in Puglia

Author

Galise, Ida, Rashid, Ivan, Cuccaro, Francesco, Bisceglia, Lucia, Coviello, Vincenzo, Melcarne, Anna, Minerba, Sante, Mincuzzi, Antonia, Assennato, Giorgio, Foschi, Roberto, Rossi, Silvia, and Gatta, Gemma

Published
2013
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15. Estimates of cancer burden in Emilia-Romagna

Author

Falcini, Fabio, Mancini, Silvia, Ravaioli, Alessandra, Vattiato, Rosa, Bucchi, Lauro, Ferretti, Stefano, Michiara, Maria, Federico, Massimo, de Leon, Maurizio Ponz, Mangone, Lucia, Rossi, Silvia, and Foschi, Roberto

Published
2013
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25. Quality of care indicators for head and neck cancers: The experience of the European Project RARECAREnet

Author

Trama, Annalisa, Botta, Laura, Foschi, Roberto, Visser, Otto, Borràs Andrés, Josep Maria, Agar, Tina, Primic-Žakelj, Maja, Bella, Francesca, Dimitrova, Nadya, Gatta, Gemma, Licitra, Lisa, and RARECAREnet High Resolution Working Group

Subjects
0301 basic medicine, medicine.medical_specialty, Cancer Research, media_common.quotation_subject, Population, Context (language use), Translational research, lcsh:RC254-282, head and neck cancers, Head cancer, 03 medical and health sciences, 0302 clinical medicine, quality of care, Indicadors de salut, medicine, Quality (business), education, Càncer de cap, media_common, Original Research, integrated care, education.field_of_study, business.industry, Head and neck cancer, Retrospective cohort study, quality indicators, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Neck cancer, Health status indicators, Integrated care, Càncer de coll, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Family medicine, population based studies, Observational study, business
Abstract

Background: Monitoring and improving quality of cancer care has become pivotal today. This is especially relevant for head and neck cancers since the disease is complex, it needs multi therapy, patients tend to be older, they tend to have comorbidities and limited social support. However, information on quality of care for head and neck cancers is scarce. In the context of the project "Information Network on Rare Cancers" we aimed to identify indicators of quality of care specific for the head and neck cancers management and to measure the quality of care for head and neck cancers in different EU Member States. Methods: We defined indicators of quality of care for head and neck cancers based on a multidisciplinary and expert-based consensus process at a European level. To test the proposed indicators, we performed an observational population-based retrospective study in four countries (Ireland, Italy, Netherlands, and Slovenia) in the years 2009-2011. Results: The main quality indicators identified are: availability of formalized multidisciplinary team, participation in clinical and translational research; timeliness of care, high quality of surgery and radiotherapy, and of pathological reporting. For head and neck cancers, the quality of care did not reach the optimal standards in most of the countries analyzed. A high proportion of patients was diagnosed at an advanced disease stage, showed delays in starting treatment (especially for radiotherapy), and there was only a very limited use of multi therapy. Conclusions: According to the achieved consensus, indicators of quality of care for head and neck cancers have to cover the patient journey (i.e., diagnosis and treatment). Our results, showed suboptimal quality of care across countries and call for solutions for ensuring good quality of care for head and neck cancer patients in all EU countries. One possible option might be to refer head and neck cancer patients to specialized centers or to networks including specialized centers.

Published
2019

27. Survival of male genital cancers (prostate, testis and penis) in Europe 1999–2007: Results from the EUROCARE-5 study

Author

Trama, Annalisa, primary, Foschi, Roberto, additional, Larrañaga, Nerea, additional, Sant, Milena, additional, Fuentes-Raspall, Rafael, additional, Serraino, Diego, additional, Tavilla, Andrea, additional, Van Eycken, Liesbet, additional, Nicolai, Nicola, additional, Hackl, M., additional, Zielonke, N., additional, Oberaigner, W., additional, Van Eycken, E., additional, Henau, K., additional, Valerianova, Z., additional, Dimitrova, N., additional, Sekerija, M., additional, Zvolský, M., additional, Dušek, L., additional, Storm, H., additional, Engholm, G., additional, Mägi, M., additional, Aareleid, T., additional, Malila, N., additional, Seppä, K., additional, Velten, M., additional, Troussard, X., additional, Bouvier, V., additional, Launoy, G., additional, Guizard, A.V., additional, Faivre, J., additional, Bouvier, A.M., additional, Arveux, P., additional, Maynadié, M., additional, Woronoff, A.S., additional, Robaszkiewicz, M., additional, Baldi, I., additional, Monnereau, A., additional, Tretarre, B., additional, Bossard, N., additional, Belot, A., additional, Colonna, M., additional, Molinié, F., additional, Bara, S., additional, Schvartz, C., additional, Lapôtre-Ledoux, B., additional, Grosclaude, P., additional, Meyer, M., additional, Stabenow, R., additional, Luttmann, S., additional, Eberle, A., additional, Brenner, H., additional, Nennecke, A., additional, Engel, J., additional, Schubert-Fritschle, G., additional, Kieschke, J., additional, Heidrich, J., additional, Holleczek, B., additional, Katalinic, A., additional, Jónasson, J.G., additional, Tryggvadóttir, L., additional, Comber, H., additional, Mazzoleni, G., additional, Bulatko, A., additional, Buzzoni, C., additional, Giacomin, A., additional, Sutera Sardo, A., additional, Mancuso, P., additional, Ferretti, S., additional, Crocetti, E., additional, Caldarella, A., additional, Gatta, G., additional, Sant, M., additional, Amash, H., additional, Amati, C., additional, Baili, P., additional, Berrino, F., additional, Bonfarnuzzo, S., additional, Botta, L., additional, Di Salvo, F., additional, Foschi, R., additional, Margutti, C., additional, Meneghini, E., additional, Minicozzi, P., additional, Trama, A., additional, Serraino, D., additional, Dal Maso, L., additional, De Angelis, R., additional, Caldora, M., additional, Capocaccia, R., additional, Carrani, E., additional, Francisci, S., additional, Mallone, S., additional, Pierannunzio, D., additional, Roazzi, P., additional, Rossi, S., additional, Santaquilani, M., additional, Tavilla, A., additional, Pannozzo, F., additional, Busco, S., additional, Bonelli, L., additional, Vercelli, M., additional, Gennaro, V., additional, Ricci, P., additional, Autelitano, M., additional, Randi, G., additional, Ponz De Leon, M., additional, Marchesi, C., additional, Cirilli, C., additional, Fusco, M., additional, F. Vitale, M., additional, Usala, M., additional, Traina, A., additional, Staiti, R., additional, Vitale, F., additional, Ravazzolo, B., additional, Michiara, M., additional, Tumino, R., additional, Giorgi Rossi, P., additional, Di Felice, E., additional, Falcini, F., additional, Iannelli, A., additional, Sechi, O., additional, Cesaraccio, R., additional, Piffer, S., additional, Madeddu, A., additional, Tisano, F., additional, Maspero, S., additional, Fanetti, A.C., additional, Zanetti, R., additional, Rosso, S., additional, Candela, P., additional, Scuderi, T., additional, Stracci, F., additional, Bianconi, F., additional, Tagliabue, G., additional, Contiero, P., additional, Dei Tos, A.P., additional, Guzzinati, S., additional, Pildava, S., additional, Smailyte, G., additional, Calleja, N., additional, Agius, D., additional, Johannesen, T.B., additional, Rachtan, J., additional, Gózdz, S., additional, Mezyk, R., additional, Blaszczyk, J., additional, Bebenek, M., additional, Bielska-Lasota, M., additional, Forjaz de Lacerda, G., additional, Bento, M.J., additional, Castro, C., additional, Miranda, A., additional, Mayer-da-Silva, A., additional, Nicula, F., additional, Coza, D., additional, Safaei Diba, C., additional, Primic-Zakelj, M., additional, Almar, E., additional, Ramírez, C., additional, Errezola, M., additional, Bidaurrazaga, J., additional, Torrella-Ramos, A., additional, Díaz García, J.M., additional, Jimenez-Chillaron, R., additional, Marcos-Gragera, R., additional, Izquierdo Font, A., additional, J. Sanchez, M., additional, Chang, D.Y.L., additional, Navarro, C., additional, Chirlaque, M.D., additional, Moreno-Iribas, C., additional, Ardanaz, E., additional, Galceran, J., additional, Carulla, M., additional, Lambe, M., additional, Khan, S., additional, Mousavi, M., additional, Bouchardy, C., additional, Usel, M., additional, M. Ess, S., additional, Frick, H., additional, Lorez, M., additional, Ess, S.M., additional, Herrmann, C., additional, Bordoni, A., additional, Spitale, A., additional, Konzelmann, I., additional, Visser, O., additional, Verhoeven, R., additional, Coleman, M., additional, Allemani, C., additional, Rachet, B., additional, Verne, J., additional, Easey, N., additional, Lawrence, G., additional, Moran, T., additional, Rashbass, J., additional, Roche, M., additional, Wilkinson, J., additional, Gavin, A., additional, Donnelly, C., additional, Brewster, D.H., additional, Huws, D.W., additional, White, C., additional, and Otter, R., additional

Published
2015
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29. Citrus fruit and cancer risk in a network of case–control studies

Author

Foschi, Roberto, primary, Pelucchi, Claudio, additional, Dal Maso, Luigino, additional, Rossi, Marta, additional, Levi, Fabio, additional, Talamini, Renato, additional, Bosetti, Cristina, additional, Negri, Eva, additional, Serraino, Diego, additional, Giacosa, Attilio, additional, Franceschi, Silvia, additional, and La Vecchia, Carlo, additional

Published
2009
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31. Family history and the risk of oral and pharyngeal cancer

Author

Garavello, Werner, primary, Foschi, Roberto, additional, Talamini, Renato, additional, La Vecchia, Carlo, additional, Rossi, Marta, additional, Dal Maso, Luigino, additional, Tavani, Alessandra, additional, Levi, Fabio, additional, Barzan, Luigi, additional, Ramazzotti, Valerio, additional, Franceschi, Silvia, additional, and Negri, Eva, additional

Published
2007
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32. Family History of Cancer and the Risk of Renal Cell Cancer

Author

Negri, Eva, primary, Foschi, Roberto, additional, Talamini, Renato, additional, Montella, Maurizio, additional, Ramazzotti, Valerio, additional, Dal Maso, Luigino, additional, Bosetti, Cristina, additional, Franceschi, Silvia, additional, Zucchetto, Antonella, additional, and La Vecchia, Carlo, additional

Published
2006
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34. A method for differentiating cancer prevalence according to health status, exemplified using a population-based sample of Italian colorectal cancer cases.

Author

Baili, Paolo, Vicentini, Massimo, Tumino, Rosario, Vercelli, Marina, Lorenzo, Michela, Foschi, Roberto, Guzzinati, Stefano, Dal Maso, Luigino, Minicozzi, Pamela, de Lorenzo, Francesco, Micheli, Andrea, and di Salvo, Francesca

Subjects
CANCER patient rehabilitation, COLON tumors, HEALTH status indicators, RECTUM tumors, RESEARCH funding, DISEASE relapse, DISEASE prevalence, DESCRIPTIVE statistics, PROGNOSIS
Abstract

Cancer prevalence is the proportion of a population diagnosed with cancer. We present a method for differentiating prevalence into the proportions expected to survive without relapse, die of cancer within a year, and die of cancer within 10 years or survive with relapse at the end of the 10th year. Material and methods. The method was applied to samples of colorectal cancer cases, randomly extracted from four Italian cancer registries (CRs). The CRs collected data on treatments, local relapses, distant relapses, and causes of death: 1) over the entire follow-up to 31 December 2007 for 601 cases diagnosed in 2002 (cohort approach); 2) over a single year (2007) for five cohorts of cases defined by year of diagnosis (from 1997 to 2001), alive at 1 January 2007 (total 298 cases). The cohorts were combined into a fictitious cohort with 10 years survival experience. For each year j after diagnosis the health status of cases alive at the beginning of j was estimated at the end of the 10th year. From these estimates the 10-year colorectal cancer prevalence was differentiated. Results. We estimated: 74.7% alive without relapse or not undergoing treatment at the end of 10 years; 8.1% had died of colorectal cancer within a year; 11.4% had died of colorectal cancer 1-10 years after diagnosis or had relapsed or were undergoing treatment at the end of the 10th year; and 5.8% had died of other causes. Conclusions. We have introduced a new method for estimating the healthcare and rehabilitation demands of cancer survivors based on CR data plus treatment and relapse data specifically collected for samples of cases archived by CRs. [ABSTRACT FROM AUTHOR]

Published
2013
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35. Cancer Rehabilitation Services: An Italian Population-based Cohort Study

Author

Di Salvo, Francesca, Baili, Paolo, Vicentini, Massimo, Tumino, Rosario, Vercelli, Marina, Pirino, Daniela, Contiero, Paolo, Foschi, Roberto, Minicozzi, Pamela, Rossi, Paolo Giorgi, de Lorenzo, Francesco, Micheli, Andrea, Marani, Enza, Orengo, Maria Antonietta, Rossi, Paolo Giorgi, Mangone, Lucia, Pellegri, Carlotta, Di Felice, Enza, Cascone, Giuseppe, Cilia, Sonia, Morana, Gabriele, Nicita, Carmela, Rollo, Concetta, Sigona, Aurora, Spata, Eugenia, Spata, Giovanna, Budroni, Mario, Cesaraccio, Rosaria, Contiero, Paolo, Maghini, Anna, Tagliabue, Giovanna, De Lorenzo, Francesco, Del Campo, Laura, Polacchi, Flaminia, Aurora, Fulvio, Vittone, Dario, Compagni, Amelia, Fattore, Giovanni, Casella, Ilaria, Cifalà, Agata, Sant, Milena, Gatta, Gemma, Trama, Annalisa, Anselmi, Valeria, and Casoli, Claudia

Abstract

Aims and Background In Italy more than 55% of cancer patients live for more than 5 years after diagnosis, sometimes with several cancer-related sequelae. For this reason rehabilitation must offer not only physical interventions but also psychological, clinical, social and nutritional support. The CAREMORE pilot study was designed to assess whether cancer registries could serve to collect information on rehabilitation services, to describe and quantify the services provided by the National Health Service, and to examine the allocation of rehabilitation services to cancer patients.Methods and Study Design This was a pilot population-based cohort study. A sample of 1200 patients was identified from the databases of the Varese, Genoa, Reggio Emilia, Sassari and Ragusa cancer registries, all diagnosed in 2002 and followed for 5 years. For 4 cancer sites a list of rehabilitation items to be collected was drafted by a joint community of researchers and voluntary associations, with variables regarding rehabilitation data and follow-up. Data were analyzed by groups of patients, vital status, sex, and age.Results This pilot study suggested it is useful to collect information on several rehabilitation services: disability benefits, home care, aids and other support; it was not possible to collect reliable information on nutritional and psychological rehabilitation. In all, 36% of the sample applied for disability benefits, but with important differences between cancer sites. Eleven percent of the sample obtained home care, with no substantial differences between cancer sites, and 16% received at least one aid, with percentages varying from 27% for rectal cancer to 8% for lymphoma patients.Conclusions The pilot study indicated that cancer registries could collect information on rehabilitation services. In the future it would be interesting to expand the roles of these registries to factors that influence quality of life, taking into account the possibility of collecting more information by actually interviewing patients.

Published
2014
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36. PATIENTS' CHARACTERISTICS, DIAGNOSTIC AND PRIMARY THERAPY PROCEDURES IN PROSTATE CANCER PATIENTS ANALYZED IN THE PERIODS 1996-1999 VS 2005-2007

Author

Botta, Laura, Trama, Annalisa, Foschi, Roberto, Nicolai, Nicola, Lodde, Michele, Seeber, Andreas, Aigner, Michael, Bellu, Francesco, Dal Cappello, Tomas, Fusco, Mario, Vitale, Maria Francesca, Pannozzou, Fabio, Natali, Maurilio, Di Croce, Antonio, Vercelli, Marina, Quaglia, Alberto, Casella, Claudia, Puppo, Antonella, Tumino, Rosario, Spata, Eugenia, Lucia Mangone, Ferrari, Francesca, Vicentini, Massimo, Piffer, Silvano, Gentilini, Maria Adalgisa, Cappelletti, Maddalena, Rizzello, Roberto, Preto, Lucia, Tagliabue, Giovanna, Contiero, Paolo, Valdagni, Riccardo, and Gatta, Gemma

37. Cancer rehabilitation services: an Italian population-based cohort study

Author

Di Salvo, Francesca, Paolo Baili, Vicentini, Massimo, Tumino, Rosario, Vercelli, Marina, Pirino, Daniela, Contiero, Paolo, Foschi, Roberto, Minicozzi, Pamela, Rossi, Paolo Giorgi, Lorenzo, Francesco, Micheli, Andrea, and Caremore, Grp

Subjects
Adult, Male, Lymphoma, Nutritional Support, Rectal Neoplasms, Breast Neoplasms, Pilot Projects, Middle Aged, Cancer rehabilitation services, Home Care Services, Cohort Studies, Disability Evaluation, Italy, Neoplasms, Colonic Neoplasms, Quality of Life, Humans, Female, Registries, Aged, Follow-Up Studies
Abstract

In Italy more than 55% of cancer patients live for more than 5 years after diagnosis, sometimes with several cancer-related sequelae. For this reason rehabilitation must offer not only physical interventions but also psychological, clinical, social and nutritional support. The CAREMORE pilot study was designed to assess whether cancer registries could serve to collect information on rehabilitation services, to describe and quantify the services provided by the National Health Service, and to examine the allocation of rehabilitation services to cancer patients.This was a pilot population-based cohort study. A sample of 1200 patients was identified from the databases of the Varese, Genoa, Reggio Emilia, Sassari and Ragusa cancer registries, all diagnosed in 2002 and followed for 5 years. For 4 cancer sites a list of rehabilitation items to be collected was drafted by a joint community of researchers and voluntary associations, with variables regarding rehabilitation data and follow-up. Data were analyzed by groups of patients, vital status, sex, and age.This pilot study suggested it is useful to collect information on several rehabilitation services: disability benefits, home care, aids and other support; it was not possible to collect reliable information on nutritional and psychological rehabilitation. In all, 36% of the sample applied for disability benefits, but with important differences between cancer sites. Eleven percent of the sample obtained home care, with no substantial differences between cancer sites, and 16% received at least one aid, with percentages varying from 27% for rectal cancer to 8% for lymphoma patients.The pilot study indicated that cancer registries could collect information on rehabilitation services. In the future it would be interesting to expand the roles of these registries to factors that influence quality of life, taking into account the possibility of collecting more information by actually interviewing patients.

38. Survival and cure trends for European children, adolescents and young adults diagnosed with acute lymphoblastic leukemia from 1982 to 2002.

Author

Gatta G, Rossi S, Foschi R, Trama A, Marcos-Gragera R, Pastore G, Peris-Bonet R, Stiller C, and Capocaccia R

Subjects
Adolescent, Age Factors, Child, Child, Preschool, Europe epidemiology, Female, History, 20th Century, History, 21st Century, Humans, Infant, Infant, Newborn, Male, Precursor Cell Lymphoblastic Leukemia-Lymphoma epidemiology, Precursor Cell Lymphoblastic Leukemia-Lymphoma history, Registries, Young Adult, Precursor Cell Lymphoblastic Leukemia-Lymphoma mortality
Abstract

Proportion cured is a potentially more informative cancer outcome measurement than 5-year survival. We present population-based estimates of cure for young patients diagnosed with acute lymphoblastic leukemia in Europe from 1982 to 2002. Thirty-five European cancer registries provided data. Survival was estimated by age, period of diagnosis and European region, and used as input for parametric cure models, which assume cured patients have the same mortality as the general population. For acute lymphoblastic leukemia diagnosed in 1-14 year olds in 2000-2002, over 77% were estimated cured. The proportion cured improved significantly over the study period: an impressive 26-58% in infants (up to 1 year), 70-90% in 1-4 year olds, 63-86% in 5-9 year olds, 52-77% in 10-14 year olds, and 44-50% in 15-24 year olds. Regional variations in proportion cured reduced over time for 1-14 year-olds, but persisted in infants and 15-24 year olds. Five-year survival was always slightly higher than proportion cured. Considerable proportions of young patients were estimated cured of acute lymphoblastic leukemia. Nevertheless, a small excess risk of death persisted beyond five years after diagnosis when patients remained at risk for late treatment effects, late relapses and second primaries.

Published
2013
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