1. Guidelines for reporting cell types: the MIRACL standard
- Author
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Lubiana, Tiago, Roncaglia, Paola, Mungall, Christopher J., Quardokus, Ellen M., Fortriede, Joshua D., Osumi-Sutherland, David, and Diehl, Alexander D.
- Subjects
Quantitative Biology - Other Quantitative Biology - Abstract
Cell types are at the root of modern biology, and describing them is a core task of the Human Cell Atlas project. Surprisingly, there are no standards for reporting new cell types, leading to a gap between classes mentioned in biomedical literature and the Cell Ontology, the primary registry of cell types. Here we introduce the Minimal Information Reporting About a CelL (MIRACL) standard, a guideline for describing cell types alongside scientific articles. In a MIRACL sheet, authors organize a label, a diagnostic description, a taxon, an anatomical structure, and a parent cell class for each cell type of interest. The MIRACL standard bridges the gap between wet-lab researchers and ontologists, facilitating the integration of biomedical knowledge into ontologies and artificial intelligence systems., Comment: 8 pages, 1 figure, 1 table
- Published
- 2022