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1. Outcomes Following Vascular and Endovascular Procedures Performed During the First COVID-19 Pandemic Wave

Author

Birmpili, Panagiota, Benson, Ruth A., Gwilym, Brenig, Nandhra, Sandip, Al-Saadi, Nina, Ambler, Graeme K., Blair, Robert, Bosanquet, David, Dattani, Nikesh, Hitchman, Louise, Hurndall, Katherine, Machin, Matthew, Onida, Sarah, Saratzis, Athanasios, Shalhoub, Joseph, Lauren, Shelmerdine, Singh, Aminder Anthony, Bosanquet, David C., Forsythe, Rachael O., Dovell, George, Preece, Ryan, Imray, Chris, Kandola, Sonia, Johnson, Adam, Choong, Andrew, Ng, Jun Jie, Aitken, Sarah, Moss, Jana-Lee, Beropoulis, Efthymios, Stavroulakis, Konstantinos, Santiago, Fabrico, Abdelhaliem, Amr, Abuduruk, Aseel, Aherne, Thomas M., Ahmed, Hazem, Aitken, Sarah J., Akhtar, Tasleem, Akkaya, Bekir B., Al Shakarchi, Julien, Algasi, Abdeljawad J., AlHamzah, Musaad, Alhumiad, Ahmed A., Allard, Bernard, Almeshal, Meshal, Alomran, Faris, AlRakaf, Reem N., Altabal, Mohamed, Altaf, Nishath, Altoijry, Abdulmajeed H., Altuwaijri, Talal, Alwehaibi, Nasser, Anderson Baker, Sara J., Angiletta, Domenico, Antoniou, Afroditi, Antoniou, George A., Areias, Libnah L., Ashcroft, James, Atkinson, Noel, Attia, Doaa, Attwell, Lukas, Azab, Mohammed A., Aziz, Omar, Azzam, Ahmed Y., Bakoyiannis, Christos, Barakat, Hashem, Bashar, Khalid, Battersby, Ruth, Benaragama, K.S., BenGhatnsh, Ahmed T.S., Bessias, Nikolaos, Bhakthavalsalan, Resya, Binkhamis, Shagran, Bootun, Roshan, Boyle, Emily, Buga, Ion, Catterson, Martin, Chambers, Jennifer L., Chandarana, Karishma, Charalabopoulos, Alexandros, Charlton, Gabriella, Cheng, Stephen W.K., Chinai, Natasha, Choudhry, Asad J., Clothier, Annie, Cohnert, Tina U., Coleman, Chloe, Costanza, Michael, Coughlin, Patrick A., Coulston, James, Cragg, James, Darvall, Katy, Davies, Emma M., Davies, Huw, Dawkins, Claire, Dawson, Joseph A., Dean, Anastasia, Dhal, Bedanta S., Duncan, Andrew, Edwards, Mark, Egan, Bridget, El Amrani, Mehdi, Elhadi, Ahmed, Elhadi, Muhammed, Eljareh, Mohamed S., Elkady, Ramy, Elkawafi, Mohamed, Elkhafeefi, Fatimah S., Elkwahad, Maysoon, Ellojli, Ibrahim A., ElSanhoury, Kareem, Elsantawy, Hazem, Elsayed, Khaled, Ennab, Raed M., Fisher, Owain, Fitridge, Robert, Flumignan, Ronald L.G., Fowler, Amy L., Galloway, Richard F., Gan, John, Garnham, Andrew, Georgopoulos, Sotirios, Ghatwary Tantawy, Tamer M.H., Goel, Ravi R., Goh, Mingzheng A., Grainger, Tabitha, Gunawansa, Nalaka, Hammond, Eric, Hanna, Joseph, Hardy, Simon C., Hardy, Thomas J., Harrison, Gareth J., Hassanin, Ahmed, Hattam, Andrew T., Hein, Martin, Hmaid, Hytham K.S., Hon, Kay, Iqbal, Kaisor, Iscan, Hakkı Z., Isik, Arda, Joyce, Doireann P., Juszczak, Maciej, Kakavia, Kiriaki, Kakkos, Stavros, Karkos, Christos D., Katsogridakis, Emmanuel, Khalil, Rana, Khallaf, Andrew I., Khan, Aazeb, Khashram, Manar, Khoo, Samantha, Kilby, Joseph, Kuang, Beatrice, Kyrou, Ioanna, Lapolla, Pierfrancesco, Leong, Kai W., Lim, Eunice, Liu, Ju-wei N., Locker, Dafydd, Luo, Xun, Lyons, Oliver T.A., Makar, Ragai R., Maras, Dimitris, Martin, Emmeline A., Mavioglu, Hayrettin L., Mazingi, Dennis, McCaslin, James, McClure, David N., McKevitt, Kevin, Meecham, Lewis, Mehta, Shreya, Minelli, Fabrizio, Mingoli, Andrea, Mitka, Afroditi M., Mohamed, Farag S., Moore, Hayley M., Morley, Rachael L., Moulakakis, Konstantinos G., Mpaili, Eustratia, Msherghi, Ahmed, Muhammad, Kamel, Muller, Juanita, Musicki, Korana, Nakano, Luis C.U., Nesbitt, Craig, Nicholls, Jonathan, Nickinson, Andrew, Nouh, Thamer, Nunag, Jose M.S., Nyamekye, Isaac K., Papanikolas, Michael J., Papas, Theofanis T., Papazoglou, Konstantinos O., Paravastu, Sharath, Parr, Noala, Pasenidou, Ketino, Pineda, Fernando Picazo, Pond, Franklin, Popplewell, Matthew A., Powezka, Katarzyna, Prce, Daniela, Premnath, Sivaram, Pulli, Raffaele, Rabee, Hussein M.M., Rahman, Habibur P., Ravintharan, Nandhini, Valdivia, Andrés Reyes, Richards, Toby, Roditis, Konstantinos, Rolls, Alexander E.S., Roy, Iain N., Saeed, Hani, Saha, Prakash, Saltiel, Alberto, Sapienza, Paolo, Scott, Emma, Selvaraj, Christopher N., Sharif, Atif, Sica, Simona, Silickas, Justinas, Singh, Gurkirat, Sivaharan, Ashwin, Sivakumaran, Yogeesan, Somaiya, Pranav, Stansby, Gerry, Stavert, Bethany M., Sudarsanam, Abhilash, Suthers, Elizabeth, Suttenwood, Helen, Taha, Ahmed, Taha, Mohamed A.H., Tam, Siu C., Tang, Alethea M., Tang, Robert, Taran, Dana, Tarusan, Lawrence, Thet, Myat S., Thomas, Jacqueline, Tierney, Sean, Tigkiropoulos, Konstantinos, Tinelli, Giovanni, Tolba, Mahmoud M.H., Travers, Hannah C., Tsagkos, Ioannis, Tshomba, Yamume, Tsiantoula, Paraskevi, Twine, Christopher P., Ulker, Berkay, Ulusoy, Serap, Unal, Ertekin U., Varley, Vincent C., Vasudevan, Thodur M., Vo, Uyen G., Wagner, Timothy, Walsh, Stewart R., Wang, Judy, Wong, Jackie, Warren, Sarah A., Yih, Chun L.P., Zacà, Sergio, Zafar, Adeel S., Zaki, Shady, Zywicka, Ewa M., Shelmerdine, Lauren, and Singh, Aminder A.

Published
2024
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2. Global impact of the first coronavirus disease 2019 (COVID‐19) pandemic wave on vascular services

Author

Benson, Ruth A, Nandhra, Sandip, Shalhoub, Joseph, Dattani, Nikesh, Ambler, Graeme K, Banquet, David C, Bosanquet, David C, Forsythe, Rachael, Onida, Sarah, Dovell, George, Hitchman, Louise, Preece, Ryan, Saratzis, Athanasios, Imray, Chris, Johnson, Adam, Choong, Andrew, Ng, Jun Jie, Aitken, Sarah, Moss, Jana-Lee, Sudarsanam, Abhilash, Tam, Adam, Beck, Adam W, Barkat, Adel, Bajwa, Adnan, Elbasty, Ahmed, Awopetu, AI, Kodama, Akio, Rivera, Aksim G, Munoz, Alberto, Saltiel, Alberto, Russo, Alejandro, Rolls, Alex, Kafetzakis, Alexandros, Kimyaghalam, Ali, Kordzadeh, Ali, Shepherd, Amanda, Singh, Aminder, Mingoli, Andrea, Lazaris, Andreas M, Isaak, Andrej, Marin, Andres, Valdivia, Andrés Reyes, Batchelder, Andrew, Duncan, Andrew, Argyriou, Angeliki, Jaipersad, Anthony S, Freyrie, Antonio, Pereira-Neves, António, Mahomed, Anver, Isik, Arda, Jawien, Arkadiusz, Choudhry, Asad J, Sivaharan, Ashwin, Giannoukas, Athanasios, Papaioannou, Athanasios, Abbas, Ayman, Christos, Bakoyiannis, Akkaya, Bekir Bogachan, Huasen, Bella, Patrice, Bibombe, Mwipatayi, Azhar, Bilal, Keldiyorov, Boboyor, Ullery, Brant W, Pratesi, Carlo, Hinojosa, Carlos A, Bechara, Carlos F, Parra, Carolina Salinas, Alexandros, Charalabopoulos, Bezard, Charlotte, Lee, Cheong Jun, Davies, Chris, Behrendt, Christian-Alexander, Lowe, Christopher, Karkos, Christos D, Yih, Chun Ling Patricia, McDonnell, Ciarán, Ordonez, Claudia, Nesbitt, Craig, Alexander, Croo, Guglielmone, Daniel, Doherty, Daniel T, Riding, David M, Esposito, Davide, Harkin, Denis, Lui, Dennis H, and Kamal, Dhafer M

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Clinical Research, Neurodegenerative, Good Health and Well Being, COVID-19, Global Health, Health Care Surveys, Health Services Accessibility, Humans, Pandemics, Practice Patterns, Physicians', Prospective Studies, Vascular Surgical Procedures, Vascular and Endovascular Research Network (VERN) COVER study collaborative*, Medical and Health Sciences, Surgery, Clinical sciences
Abstract

This online structured survey has demonstrated the global impact of the COVID-19 pandemic on vascular services. The majority of centres have documented marked reductions in operating and services provided to vascular patients. In the months during recovery from the resource restrictions imposed during the pandemic peaks, there will be a significant vascular disease burden awaiting surgeons. One of the most affected specialties.

Published
2020

4. Assessment of abdominal aortic aneurysm biology using magnetic resonance imaging and positron emission tomography-computed tomography

Author

Forsythe, Rachael Olivia, Newby, David, and Robson, Jenny

Subjects
616.1, abdominal aortic aneurysm, AAA, magnetic resonance imaging, MRI, USPIO, inflammation, positron emission tomography, PET-CT, aneurysm growth, clinical assessment
Abstract

Background Although abdominal aortic aneurysm (AAA) growth is non-linear, serial measurements of aneurysm diameter are the mainstay of aneurysm surveillance and contribute to decisions on timing of intervention. Aneurysm biology plays a key part in disease evolution but is not currently routinely assessed in clinical practice. Magnetic Resonance Imaging (MRI) and Positron Emission Tomography-Computed Tomography (PET-CT) provide insight into disease processes on a cellular or molecular level, and represent exciting new imaging biomarkers of disease activity. Macrophage-mediated inflammation may be assessed using ultrasmall superparamagnetic particles of iron oxide (USPIO) MRI and the PET radiotracer 18FSodium Fluoride (18F-NaF) identifies microcalcification which is a response to underlying necrotic inflammation. The central aim of this thesis was to investigate these imaging modalities in patients with AAA. Methods and Results USPIO MRI: MULTI-CENTRE STUDY In a prospective multi-centre observational cohort study, 342 patients (85.4% male, mean age 73.1±7.2 years, mean AAA diameter 49.6±7.7mm) with asymptomatic AAA ≥4 cm anteroposterior diameter underwent MRI before and 24-36 hours after intravenous administration of USPIO. Colour maps (depicting the change in T2* caused by USPIO) were used to classify aneurysms on the basis of the presence of USPIO uptake in the aneurysm wall, representing mural inflammation. Intra- and inter-observer agreement were found to be very good, with proportional agreement of 0.91 (kappa 0.82) and 0.83 (kappa 0.66), respectively. At 1 year, there was 29.3% discordant classification of aneurysms on repeated USPIO MRI and at 2 years, discordance was 65%, suggesting that inflammation evolves over time. In the observational study, after a mean of 1005±280 days of follow up, there were 126 (36.8%) aneurysm repairs and 17 (5.0%) ruptures. Participants with USPIO enhancement (42.7%) had increased aneurysm expansion rates (3·1±2·5 versus 2·5±2·4 mm/year; difference 0·6 [95% confidence intervals (CI), 0·02 to 1·2] mm/year, p=0·0424) and had higher rates of aneurysm rupture or repair (69/146=47·3% versus 68/191=35·6%; difference 11·7%, 95% CI 1·1 to 22·2%, p=0·0308). USPIO MRI was therefore shown to predict AAA expansion and the composite of rupture or repair, however this was not independent of aneurysm diameter (c-statistic, 0·7924 to 0·7926; unconditional net reclassification -13·5%, 95% confidence intervals -36·4% to 9·3%). 18F-NaF PET-CT: SINGLE-CENTRE STUDY A sub-group of 76 patients also underwent 18F-NaF PET-CT, which was evaluated using the maximum tissue-to-background ratio (TBRmax) in the most diseased segment (MDS), a technique that showed very good intra- (ICC 0.70-0.89) and inter-observer (ICC 0.637-0.856) agreement. Aneurysm tracer uptake was compared firstly in a case-control study, with 20 patients matched to 20 control patients for age, sex and smoking status. 18F-NaF uptake was higher in aneurysm when compared to control aorta (log2TBRmax 1.712±0.560 vs. 1.314±0.489; difference 0.398 (95% CI 0.057, 0.739), p=0.023), or to non-aneurysmal aorta in patients with AAA (log2TBRmax 1.647±0.537 vs. 1.332±0.497; difference 0.314 (95% CI 0.0685, 0.560), p=0.004). An ex vivo study was performed on aneurysm and control tissue, which demonstrated that 18F-NaF uptake on microPET-CT was higher in the aneurysm hotspots and higher in aneurysm tissue compared to control tissue. Histological analysis suggested that 18F-NaF was highest in areas of focal calcification and necrosis. In an observational cohort study, aneurysms were stratified by tertiles of TBRmax in the MDS and followed up for 510±196 days, with 6 monthly serial ultrasound measurements of diameter. Those in the highest tertile of tracer uptake expanded more than 2.5 times more rapidly than those in the lowest tertile (3.10 [3.58] mm/year vs. 1.24 [2.41] mm/year, p=0.008) and were also more likely to experience repair or rupture (15.3% vs. 5.6%, log-rank p=0.043). In multivariable analyses, 18F-NaF uptake on PET-CT emerged as an independent predictor of AAA expansion (p=0.042) and rupture or repair (HR 2.49, 95% CI1.07, 5.78; p=0.034), even when adjusted for age, sex, body mass index, systolic blood pressure, current smoking and, crucially, aneurysm diameter. Conclusion These are the largest USPIO MRI and PET-CT studies in AAA disease to date and the first to investigate 18F-NaF. Both USPIO MRI and 18F-NaF PET-CT are able to predict AAA expansion and the composite of rupture and repair, with 18F-NaF PETCT emerging as the first imaging biomarker that independently predicts expansion and AAA events, even after adjustment for aneurysm diameter. This represents an exciting new predictor of disease progression that adds incremental value to standard clinical assessments. Feasibility and randomised clinical trials are now required to assess the potential of this technique to change the management and outcome of patients with AAA.

Published
2018

7. The Relationship Between CT-derived Cervical Muscle Mass and Quality, Systemic Inflammation, and Survival in Symptomatic Patients Undergoing Carotid Endarterectomy

Author

Bradley, Nicholas, primary, Dosanj, Karamonique, additional, Ming Chan, Sharon Yen, additional, Wilson, Alasdair, additional, Siddiqui, Tamim, additional, Forsythe, Rachael, additional, Roxburgh, Campbell S.D., additional, McMillan, Donald C., additional, and Guthrie, Graeme J.K., additional

Published
2024
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11. Editor's Choice – Acute Kidney Injury (AKI) in Aortic Intervention: Findings From the Midlands Aortic Renal Injury (MARI) Cohort Study

Author

Sidloff, David, Dovell, George, Forsythe, Rachael, Barnett, Loretta, Barnet, Henrietta, Wollaston, Julie, Goodyear, Stephen, Mahmood, Asif, Matharu, Nicholas, Harrison, Seamus, Boyle, Jonathan, Parker, Emma, Carlin, Abigail, Burrows, Mandy, Lane, Tristan, Shalhoub, Joseph, Garnham, Andrew, Begum, Safia, Stather, Phil, Thrush, Jessica, Martin, Terry, Fairhead, Jack, Al Shakarchi, Julien, Wallace, Tom, Wall, Elaine, Twine, Christopher, Al-Jundi, Wissam, Davies, Huw, Barker, Tom, Lopez, Edward, Saratzis, Athanasios, Joshi, Shivam, Benson, Ruth A., Bosanquet, David, Dattani, Nikesh, Batchelder, Andrew, Fisher, Owain, Ioannidou, Eva, Bown, Matthew J., and Imray, Christopher H.

Published
2020
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17. Aspirin versus placebo for the treatment of venous leg ulcers—a phase II, pilot, randomised trial (AVURT)

Author

Tilbrook Helen, Cook Liz, Clark Laura, Sbizzera Illary, Bland Martin, Buckley Hannah, Chetter Ian, Dumville Jo, Fenner Chris, Forsythe Rachael, Gabe Rhian, Harding Keith, Layton Alison, Lindsay Ellie, Mc Daid Catriona, Moffatt Christine, Rolfe Debbie, Stansby Gerard, Torgerson David, Vowden Peter, Williams Laurie, and Hinchliffe Robert

Subjects
Trial, Pilot, Randomised, Aspirin, Placebo, Venous, Medicine (General), R5-920
Abstract

Abstract Background Venous leg ulcers (VLUs) can take many months to heal and 25% fail to heal. The main treatment for venous leg ulcers is compression therapy and few additional therapies exist. Two previous trials indicated that low-dose aspirin may improve healing time, but these trials were insufficiently robust. Methods A multi-centred, pilot, phase II, randomised, double blind, parallel-group, placebo-controlled, efficacy trial (RCT) was conducted to determine: if aspirin improves VLU healing time; the safety of aspirin in this population; treatment compliance; and the feasibility of recruitment to a phase III trial. We recruited patients from secondary care who were aged ≥ 18 years, had a chronic VLU and not regularly taking aspirin. Participants were randomly assigned (1:1) to receive 300 mg of daily aspirin or placebo in addition to standard care, which consisted of multi component compression therapy aiming to deliver 40 mmHg at the ankle where possible. The randomisation list was stratified by ulcer size (≤ 5 cm2 or > 5 cm2). The primary endpoint was time to ulcer healing, which was defined as ‘complete epithelial healing in the absence of scab (eschar) with no dressing required’. Safety outcomes were assessed in all participants who received at least one dose of the study drug. Results Twenty-seven patients were recruited from eight sites (target 100 patients). A short time-frame to recruit and a large number of patients failing to meet the eligibility criteria were the main barriers to recruitment. There was no evidence of a difference in time to healing of the reference ulcer following adjustment for log ulcer area and duration (hazard ratio 0.58, 95% confidence interval 0.18 to 1.85; p = 0.357). One expected serious adverse event related to aspirin was recorded. A number of options to improve recruitment were explored. Conclusions There was no evidence that aspirin was effective in expediting the healing of chronic VLUs. However, the analysis was underpowered due to the low number of participants recruited. The trial design would require substantial amendment in order to progress to a phase III (effectiveness) trial. Trial registration Clinicaltrials.gov, NCT02333123. Registered on 5 November 2014.

Published
2019
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18. 18F–Sodium Fluoride Uptake in Abdominal Aortic Aneurysms: The SoFIA3 Study

Author

Forsythe, Rachael O., Dweck, Marc R., McBride, Olivia M.B., Vesey, Alex T., Semple, Scott I., Shah, Anoop S.V., Adamson, Philip D., Wallace, William A., Kaczynski, Jakub, Ho, Weiyang, van Beek, Edwin J.R., Gray, Calum D., Fletcher, Alison, Lucatelli, Christophe, Marin, Aleksander, Burns, Paul, Tambyraja, Andrew, Chalmers, Roderick T.A., Weir, Graeme, Mitchard, Neil, Tavares, Adriana, Robson, Jennifer M.J., and Newby, David E.

Published
2018
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20. Contributors

Author

Akers, Emma, primary, Alexopoulos, Nikolaos, additional, Al Hussein Alawamlh, Omar, additional, Ali, Ziad A., additional, Al’Aref, Subhi J., additional, Bax, A. Maxim, additional, Bellasi, Antonio, additional, Boehm, Manfred, additional, Cudrici, Cornelia D., additional, Di Bartolo, Belinda, additional, Doris, Mhairi, additional, Dweck, Marc, additional, Ferrante, Elisa A., additional, Finn, Aloke V., additional, Forsythe, Rachael, additional, Hecht, Harvey, additional, Jinnouchi, Hiroyuki, additional, Larine, Daria, additional, Maehara, Akiko, additional, Maslov, Petra Zubin, additional, Matsumura, Mitsuaki, additional, Min, James K., additional, Mintz, Gary S., additional, Narula, Jagat, additional, Newby, David E., additional, Nicholls, Stephen J., additional, Raggi, Paolo, additional, Sakamoto, Atsushi, additional, Syed, Maaz B.J., additional, Torii, Sho, additional, van den Hoogen, Inge J., additional, van Rosendael, Alexander R., additional, and Virmani, Renu, additional

Published
2019
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22. Aortic sodium [18F]fluoride uptake following endovascular aneurysm repair

Author

Debono, Samuel, primary, Nash, Jennifer, additional, Fletcher, Alexander J, additional, Syed, Maaz, additional, van Beek, Edwin J R, additional, Williams, Michelle Claire, additional, Falah, Orwa, additional, Tambyraja, Andrew, additional, Dweck, Marc R, additional, Newby, David E, additional, and Forsythe, Rachael O, additional

Published
2023
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27. Aortic sodium [18F]fluoride uptake following endovascular aneurysm repair.

Author

Debono, Samuel, Nash, Jennifer, Fletcher, Alexander J., Syed, Maaz, van Beek, Edwin J. R., Williams, Michelle Claire, Falah, Orwa, Tambyraja, Andrew, Dweck, Marc R., Newby, David E., and Forsythe, Rachael O.

Subjects
ENDOVASCULAR aneurysm repair, ENDOVASCULAR surgery, ATHEROSCLEROTIC plaque, BLOOD vessel prosthesis, AORTIC rupture, AORTA, POSITRON emission tomography computed tomography
Published
2023
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29. Emerging techniques in atherosclerosis imaging

Author

Kaczynski Jakub, Jakub Kaczynski, O Forsythe Rachael, Maaz Syed, David E. Newby, E Newby David, J Fletcher Alexander, B J Syed Maaz, Rachael O. Forsythe, Edwin J.R. van Beek, Marc R. Dweck, R Dweck Marc, and Alexander J. Fletcher

Subjects
Metabolic state, cardiovascular risk, medicine.medical_specialty, Modalities, ultrasound diagnostics, positron emission tomography, optical coherence tomography, medicine.diagnostic_test, business.industry, Computer applications to medicine. Medical informatics, Atherosclerotic disease, R858-859.7, Disease, medicine.disease, molecular imaging, radiology, Stenosis, Atherosclerosis imaging, Positron emission tomography, medicine, Image acquisition, magnetic resonance imaging, Radiology, atherosclerosis, business
Abstract

Atherosclerosis is a chronic immunomodulated disease that affects multiple vascular beds and results in a significant worldwide disease burden. Conventional imaging modalities focus on the morphological features of atherosclerotic disease such as the degree of stenosis caused by a lesion. Modern CT, MR and positron emission tomography scanners have seen significant improvements in the rapidity of image acquisition and spatial resolution. This has increased the scope for the clinical application of these modalities. Multimodality imaging can improve cardiovascular risk prediction by informing on the constituency and metabolic processes within the vessel wall. Specific disease processes can be targeted using novel biological tracers and smart contrast agents. These approaches have the potential to inform clinicians of the metabolic state of atherosclerotic plaque. This review will provide an overview of current imaging techniques for the imaging of atherosclerosis and how various modalities can provide information that enhances the depiction of basic morphology. This publication is the reprint with Russian translation from original: Syed MB, Fletcher AJ, Forsythe RO, Kaczynski J, Newby DE, Dweck MR, van Beek EJ. Emerging techniques in atherosclerosis imaging. Br J Radiol. 2019;92(1103):20180309. doi: 10.1259/bjr.20180309.

Published
2021

30. 18F-NaF PET/MRI for Detection of Carotid Atheroma in Acute Neurovascular Syndrome

Author

Kaczynski, Jakub, primary, Sellers, Stephanie, additional, Seidman, Michael A., additional, Syed, Maaz, additional, Dennis, Martin, additional, Mcnaught, Gillian, additional, Jansen, Maurits, additional, Semple, Scott I., additional, Alcaide-Corral, Carlos, additional, Tavares, Adriana A. S., additional, MacGillivray, Thomas, additional, Debono, Samuel, additional, Forsythe, Rachael, additional, Tambyraja, Andrew, additional, Slomka, Piotr J., additional, Leipsic, Jonathon, additional, Dweck, Marc R., additional, Whiteley, William, additional, Wardlaw, Joanna, additional, van Beek, Edwin J. R., additional, Newby, David E., additional, and Williams, Michelle C., additional

Published
2022
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34. Statement on workforce

Author

King, Martin, primary, Shelton, Fenella, additional, Kalra, Neeraj, additional, Adebayo, Oliver, additional, Harvey, Neil, additional, Sarmah, Panchali, additional, Nieto, Tom, additional, Jiwa, Natasha, additional, Vaughan, Elizabeth, additional, Sharma, Divya, additional, Taylor, Kirstie, additional, Forsythe, Rachael, additional, Laing, Richard, additional, Jackson, Raef, additional, and Gadallah, Bassem, additional

Published
2022
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37. 18F-Fluoride and 18F-Fluorodeoxyglucose Positron Emission Tomography After Transient Ischemic Attack or Minor Ischemic Stroke: Case–Control Study

Author

Vesey, Alex T., Jenkins, William S. A., Irkle, Agnese, Moss, Alastair, Sng, Greg, Forsythe, Rachael O., Clark, Tim, Roberts, Gemma, Fletcher, Alison, Lucatelli, Christophe, Rudd, James H. F., Davenport, Anthony P., Mills, Nicholas L., Al-Shahi Salman, Rustam, Dennis, Martin, Whiteley, William N., van Beek, Edwin J. R., Dweck, Marc R., and Newby, David E.

Published
2017
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38. Quantifying 18F-sodium fluoride uptake in abdominal aortic aneurysms

Author

Debono, Samuel, primary, Nash, Jennifer, additional, Fletcher, Alexander J., additional, Syed, Maaz B. J., additional, Semple, Scott I., additional, Beek, Edwin J. R. van, additional, Fletcher, Alison, additional, Cadet, Sebastien, additional, Williams, Michelle C, additional, Dey, Damini, additional, Slomka, Piotr J., additional, Forsythe, Rachael O., additional, Dweck, Marc R., additional, and Newby, David E., additional

Published
2022
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39. Additional file 1 of Quantifying sodium [18F]fluoride uptake in abdominal aortic aneurysms

Author

Debono, Samuel, Nash, Jennifer, Fletcher, Alexander J., Syed, Maaz B. J., Semple, Scott I., van Beek, Edwin J. R., Fletcher, Alison, Cadet, Sebastien, Williams, Michelle C., Dey, Damini, Slomka, Piotr J., Forsythe, Rachael O., Dweck, Marc R., and Newby, David E.

Subjects
parasitic diseases, cardiovascular system
Abstract

Additional file1. Figure S1: Radiotracer uptake in different regions of the aorta, Maximum tissue-to-background ratio (red) and maximum aortic microcalcification activity (blue) in the regions of the abdominal aorta and the thoracic aorta. AMA, aortic microcalcification activity; max, maximum; TBR, tissue-to-background ratio. * = p < 0.05, ** = p < 0.01, *** = p < 0.001, **** = p < 0.0001. Figure S2: Scatter plots of the different values quantifying sodium [18F]fluoride in the abdominal aorta, TBRmax and AMAmax values (a), TBRmean and AMA (b), one observer performing the same AMA method twice (c), two observers performing the same AMA method (d). AMA, aortic microcalcification activity; max, maximum; R, Pearson’s correlation coefficient; TBR, tissue-to-background ratio.

Published
2022
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40. Low Shear Stress at Baseline is Associated with Aortic Expansion and Aneurysm Related Events in Patients with Abdominal Aortic Aneurysms

Author

Bappoo, Nikhilesh, primary, Syed, Maaz, additional, Khinsoe, Georgia, additional, Kelsey, Lachlan, additional, Forsythe, Rachael, additional, Powell, Janet, additional, Conlisk, Noel, additional, Hoskins, Peter, additional, McBride, Olivia, additional, Shah, Anoop, additional, Jansen, Shirley, additional, Norman, Paul, additional, Newby, David, additional, and Doyle, Barry, additional

Published
2022
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45. Contributors

Author

Al Shakarchi, Julien, Bellamkonda, Kirthi, Belmonte, Romain, Björck, Martin, Black, Stephen, Coughlin, Patrick, Fitridge, Robert, Forsythe, Rachael O., Game, Fran, Garnham, Andrew, Gawenda, Michael, Gohel, Manjit S., Guo, Shigong, Hinchliffe, Robert J., Holt, Peter, Katib, Nedal, Kiely, Patrick D.W., Le, Thanh-Phong, le Roux, Dirk A., Lebuhotel, Iris, Lloyd, Mark E., Loftus, Ian, McCafferty, Ian, Mylankal, Kurian J., Naylor, A. Ross, Ricco, Jean-Baptiste, Rolls, Alexander, Russell, David, Saha, Prakash, Schermerhorn, Marc L., Soden, Peter A., Strijkers, Rob H.W., Süss, Jan David, Tambyraja, Andrew L., Tripathi, Ramesh Kaushal, van den Berg, Jos C., van Marle, Jacobus, Varcoe, Ramon L., Wade, Jacqueline E., and Wittens, Cees H.A.

Published
2024
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47. Groin Wound Infection after Vascular Exposure (GIVE) Risk Prediction Models: Development, Internal Validation, and Comparison with Existing Risk Prediction Models Identified in a Systematic Literature Review

Author

Gwilym, Brenig L., primary, Ambler, Graeme K., additional, Saratzis, Athanasios, additional, Bosanquet, David C., additional, Stather, Philip, additional, Singh, Aminder, additional, Mancuso, Enrico, additional, Arifi, Mohedin, additional, Altabal, Mohamed, additional, Elhadi, Ahmed, additional, Althini, Abdulmunem, additional, Ahmed, Hazem, additional, Davies, Huw, additional, Rangaraju, Madhu, additional, Juszczak, Maciej, additional, Nicholls, Jonathan, additional, Platt, Nicholas, additional, Olivier, James, additional, Kirkham, Emily, additional, Cooper, David, additional, Roy, Iain, additional, Harrison, Gareth, additional, Ackah, James, additional, Mittapalli, Devender, additional, Barry, Ian, additional, Richards, Toby, additional, Elbasty, Ahmed, additional, Moore, Hayley, additional, Bajwa, Adnan, additional, Duncan, Andrew, additional, Batchelder, Andrew, additional, Vanias, Tryfon, additional, Brown, Matthew, additional, Yap, Trixie, additional, Green, Lucy, additional, Smith, George, additional, Hurst, Katherine, additional, Rodriguez, Daniel U., additional, Schofield, Ella, additional, Danbury, Hannah, additional, Wallace, Tom, additional, Forsyth, James, additional, Stimpson, Amy, additional, Hopkins, Luke, additional, Mohiuddin, Kamran, additional, Nandhra, Sandip, additional, Mohammadi-Zaniani, Ghazaleh, additional, Tigkiropoulos, Konstantinos, additional, Shalan, Ahmed, additional, Bashar, Khalid, additional, Sam, Rachel, additional, Forrest, Craig, additional, Debono, Samuel, additional, Hussey, Keith, additional, Falconer, Rachel, additional, Korambayil, Salil, additional, Brennan, Ciaran, additional, Wilson, Thomas, additional, Jones, Aled, additional, Hardy, Tom, additional, Burton, Hannah, additional, Cowan, Andrew, additional, Contractor, Ummul, additional, Townsend, Elaine, additional, Grant, Olivia, additional, Cronin, Michelle, additional, Rocker, Michael, additional, Lowry, Danielle, additional, Clothier, Annie, additional, Locker, Dafydd, additional, Forsythe, Rachael, additional, McBride, Olivia, additional, Eng, Calvin, additional, Jamieson, Russell, additional, Altaf, Nishath, additional, Picazo, Fernando, additional, Sieunarine, Kishore, additional, Benson, Ruth A., additional, Crichton, Alexander, additional, Dattani, Nikesh, additional, Akhtar, Tasleem, additional, Suttenwood, Helen, additional, Guest, Francesca, additional, Wardle, Bethany, additional, Dovell, George, additional, Chinai, Natasha, additional, Bosanquet, David, additional, Hinchliffe, Robert, additional, Beckitt, Timothy, additional, Wafi, Arsalan, additional, Thapar, Ankur, additional, Moxey, Paul, additional, Lane, Tristan, additional, Preece, Ryan, additional, Naidoo, Kamil, additional, Patterson, Benjamin, additional, Perrott, Claire, additional, Shalhoub, Joseph, additional, Aherne, Thomas, additional, Hassanin, Ahmed, additional, Boyle, Emily, additional, Egan, Bridget, additional, Tierney, Sean, additional, Patel, Shaneel, additional, Birmpili, Panagiota, additional, Kandola, Sandhir, additional, Neequaye, Simon, additional, Elhadi, Muhammed, additional, Msherghi, Ahmed, additional, Khaled, Ala, additional, Meecham, Lewis, additional, Fisher, Owain, additional, Mahmood, Asif, additional, Milgrom, David, additional, Burke, Kerry, additional, Saleh, Faris, additional, and Al-Samarneh, Tariq, additional

Published
2021
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48. 161 18F-sodium fluoride positron emission tomography in acute aortic syndrome

Author

Syed, Maaz, primary, Fletcher, Alexander, additional, Debono, Samuel, additional, Forsythe, Rachael, additional, Williams, Michelle, additional, Dweck, Marc, additional, Tavares, Adriana, additional, Macaskill, Mark, additional, Shah, Anoop, additional, Denvir, Martin, additional, Lim, Kelvin, additional, Wallace, William, additional, Kaczynski, Jakub, additional, Clark, Tim, additional, Sellers, Stephanie, additional, Masson, Neil, additional, Falah, Orwa, additional, Chalmers, Roderick, additional, Tambyraja, Andrew, additional, van Beek, Edwin, additional, and Newby, David, additional

Published
2021
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