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Serotonin is crucial in gastrointestinal functions, including motility, sensitivity, secretion, and the inflammatory response. The serotonin transporter (SERT), responsible for serotonin reuptake and signaling termination, plays a prominent role in gastrointestinal physiology, representing a promising therapeutic target in digestive disorders. Serotonin transporter expression has been poorly investigated in veterinary medicine, under both healthy and pathological conditions, including canine chronic enteropathy, in which the serotonin metabolism seems to be altered. The aim of the present study was to determine the distribution of SERT immunoreactivity (SERT-IR) in the dog intestine and to compare the findings with those obtained in the rat and human intestines. Serotonin transporter-IR was observed in canine enterocytes, enteric neurons, lamina propria cells and the tunica muscularis. Data obtained in dogs were consistent with those obtained in rats and humans. Since the majority of the serotonin produced by the body is synthesized in the gastrointestinal tract, SERT-expressing cells may exert a role in the mechanism of serotonin reuptake.

Technical-economic diagnosis and proposal at farm level for two family livestock producers in the northern territory of Santa Fe, Argentina.The objective of this paper was to make diagnose of two small livestock farms in the north of the province of Santa Fe and propose and evaluate an intervention strategy using the case study methodology. The analysed family production systems are vulnerable because the low perceived incomes can put their existence at risk by not allowing remuneration for family and salaried labour and the fulfilment of fi nancial obligation. The proposal at farm level consists of incorporate a subtropical legume, dual purpose, which can increase the production gross value by the sale of seeds and by the improvement in livestock productivity. El objetivo del trabajo fue realizar un diagnóstico de dos pequeñas explotaciones ganaderas del norte de la provincia de Santa Fe y proponer y evaluar una estrategia de intervención utilizando la metodología de casos de estudio. Los sistemas de producción familiares analizados son vulnerables porque los bajos ingresos percibidos ponen en riesgo su existencia al no permitir retribuir la mano de obra familiar y asalariada y el cumplimiento de obligaciones financieras. La propuesta consiste en incorporar una leguminosa subtropical, doble propósito, que puede incrementar el valor bruto de la producción por la venta de las semillas y por la mejora en la productividad ganadera. &nbsp

In the original article, there was a mistake in the legend for Figure 3 as published. The legend of Figure 3 (g-l) is incorrect. The correct legend appears below. FIGURE 3 | Photomicrographs of cryosections of canine cervical (C8) dorsal root ganglion showing cannabinoid receptor 2- (CB2), glial fibrillary acidic protein- (GFAP), and CD31-immunoreactivity. (a–c) Stars indicate NeuroTrace labeled (a) dorsal root ganglion sensory neurons which were CB2 receptor negative (b), as well as the satellite glial cells (white arrows). (d–f) Stars indicate sensory neurons encircled by satellite glial cells (white arrows) which were GFAP-immunoreactive (e) and CB2 receptor negative. CB2 receptor immunoreactivity was expressed by Schwann cells and neuronal nuclei (open arrow). (g–i) The empty arrow indicates one neuronal axon that bifurcates (T-junction) in its central and peripheral portions (large white arrows). The small arrows indicate the nuclei of Schwann cells. (j–l) Open arrows indicate smooth muscle cells (vessel on the left) and pericyte-like cells (elongated and thin blood vessel on the right) showing CB2 receptor immunoreactivity (j).White arrows indicate endothelial cells showing CD31 immunoreactivity (k). Bar: a–f, j–l = 50μm; g–i = 100 μm. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.