1. [The relationship between ligation of the ductus arteriosus and intracranial hemorrhage in preterm infants].
- Author
-
Massone ML, Soliani M, Puccio V, Bracco G, Forcheri C, Pongiglione G, Bava G, Magnano GM, and Toma P
- Subjects
- Cerebral Hemorrhage diagnostic imaging, Cerebral Hemorrhage epidemiology, Ductus Arteriosus surgery, Ductus Arteriosus, Patent complications, Echoencephalography, Humans, Infant, Low Birth Weight, Infant, Newborn, Infant, Premature, Intraoperative Care, Ligation, Postoperative Complications diagnostic imaging, Postoperative Complications epidemiology, Retrospective Studies, Risk Factors, Cerebral Hemorrhage etiology, Ductus Arteriosus, Patent surgery, Postoperative Complications etiology
- Abstract
Surgical closure of patent ductus arteriosus (PDA) and perioperative time have been proposed as conditions of increased risk of peri-intraventricular hemorrhage (PVH-IVH) in preterm infants. We examined by pre- and postoperative ultrasound (US) scan 15 low birth-weight neonates who underwent PDA ligation within the first two weeks of life. They were assessed with regard to clinical state, perioperative management and development of PVH-IVH. Fourteen did not show onset or extension of intracranial hemorrhage in the immediate postoperative period. One patient developed a wide III grade IVH in the 24 perioperative hours. His conditions were particularly severe, suggesting that many factors such as acidosis, hypoxia, hypercapnia and hypotension might have combined to lead to hemorrhage. We conclude that PDA ligation is not likely to increase the risk of PVH-IVH per se.
- Published
- 1990