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297 results on '"Foppa, Murilo"'

1. Detection of Left Ventricular Systolic Dysfunction From Electrocardiographic Images.

Author

Sangha, Veer, Nargesi, Arash, Dhingra, Lovedeep, Khunte, Akshay, Mortazavi, Bobak, Ribeiro, Antônio, Banina, Evgeniya, Adeola, Oluwaseun, Garg, Nadish, Brandt, Cynthia, Miller, Edward, Ribeiro, Antonio, Velazquez, Eric, Giatti, Luana, Barreto, Sandhi, Foppa, Murilo, Ouyang, David, Krumholz, Harlan, Khera, Rohan, and Yuan, Neal

Subjects
artificial intelligence, biomedical technology, electrocardiography, heart failure, machine learning, ventricular dysfunction, left, Adult, Humans, Prospective Studies, Longitudinal Studies, Electrocardiography, Ventricular Dysfunction, Left, Ventricular Function, Left
Abstract

BACKGROUND: Left ventricular (LV) systolic dysfunction is associated with a >8-fold increased risk of heart failure and a 2-fold risk of premature death. The use of ECG signals in screening for LV systolic dysfunction is limited by their availability to clinicians. We developed a novel deep learning-based approach that can use ECG images for the screening of LV systolic dysfunction. METHODS: Using 12-lead ECGs plotted in multiple different formats, and corresponding echocardiographic data recorded within 15 days from the Yale New Haven Hospital between 2015 and 2021, we developed a convolutional neural network algorithm to detect an LV ejection fraction 27-fold higher odds of LV systolic dysfunction on transthoracic echocardiogram (odds ratio, 27.5 [95% CI, 22.3-33.9] in the held-out set). Class-discriminative patterns localized to the anterior and anteroseptal leads (V2 and V3), corresponding to the left ventricle regardless of the ECG layout. A positive ECG screen in individuals with an LV ejection fraction ≥40% at the time of initial assessment was associated with a 3.9-fold increased risk of developing incident LV systolic dysfunction in the future (hazard ratio, 3.9 [95% CI, 3.3-4.7]; median follow-up, 3.2 years). CONCLUSIONS: We developed and externally validated a deep learning model that identifies LV systolic dysfunction from ECG images. This approach represents an automated and accessible screening strategy for LV systolic dysfunction, particularly in low-resource settings.

Published
2023

7. Worldwide Disparities in Recovery of Cardiac Testing 1 Year Into COVID-19

Author

Einstein, Andrew J., Paez, Diana, Dondi, Maurizio, Better, Nathan, Cerci, Rodrigo, Dorbala, Sharmila, Karthikeyan, Ganesan, Pascual, Thomas N.B., Shaw, Leslee J., Villines, Todd C., Vitola, Joao V., Williams, Michelle C., Pynda, Yaroslav, Hinterleitner, Gerd, Lu, Yao, Morozova, Olga, Xu, Zhuoran, Hirschfeld, Cole B., Cohen, Yosef, Erinne, Ikenna, Malkovskiy, Eli, Randazzo, Michael, Sewanan, Lorenzo, Shetty, Mrinali, Choi, Andrew, Lopez-Mattei, Juan, Parwani, Purvi, Goda, Artan, Shirka, Ervina, Bouyoucef, Salah, Chelghoum, Lydia, Mansouri, Farouk, Medjahedi, Abdelkader, Naili, Qais, Ridouh, Mokhtar, Alasia, Diego, Alberghina, Lucia, Aramayo, Natalia, Buchara, Diego, Busso, Franco Gabriel, Bustos Rivadero, Jose Javier, Camilletti, Jorge, Campanelli, Hugo, Campisi, Roxana, Castro, Ricardo Belisario, Daicz, Mariana, del Riego, Horacio, Dragonetti, Laura, Echazarreta, Diego, Erriest, Juan, Faccio, Fernando, Facello, Adolfo, Gallegos, Hugo, Geronazzo, Ricardo, Glait, Horacio, Hasbani, Victor, Jäger, Victor, Lewkowicz, Julio Manuel, Lotti, Jose, Maciel, Neiva, Masoli, Osvaldo, Mastrovito, Edgardo, Medus, Maria, Merani, Maria Fernanda, Molteni, Susana, Montecinos, Marcos, Parisi, Gustavo, Sueldo, Claudio Pereyra, Perez de Arenaza, Diego, Quintana, Luis, Radzinschi, Alejandro, Redruello, Marcela, Rodríguez, Marina, Rojas, Horacio, Acuña, Arturo Romero, Schere, Daniel, Traverso, Sonia, Vazquez, Gustavo, Zeffiro, Susana, Sakanyan, Mari, Beuzeville, Scott, Boktor, Raef, Crowley, Michael, Downie, D'Arne, Dwivedi, Girish, Elison, Barry, Farouque, Omar, Jasper, Kim, Joshi, Subodh, Lee, Joseph, Lee, Kenneth, Lui, Elaine, Mcconachie, Peter, Meaker, Joanne, Nandurkar, Dee, Neill, Johanne, O'Rourke, Edward, O'Sullivan, Patricia, Pandos, George, Premaratne, Manuja, Prior, David, Rutherford, Natalie, Saunders, Connor, Taubman, Kim, Tauro, Andrew, Taylor, Andrew, Theuerle, James, Thomas, Paul, Tow, Jonathan, Upton, Anthony, Vamadevan, Shankar, Wayne, Victor, Wegner, Eva Alina, Wong, David, Younger, John, Beitzke, Dietrich, Feuchtner, Gudrun, Sommer, Oliver, Weiss, Konrad, Maroz-Vadalazhskaya, Natallia, Tserakhau, Uladzimir, Homans, Filip, Van De Heyning, Caroline M., Araujo, Raúl, Soldat-Stankovic, Valentina, Stankovic, Sinisa, Almeida, Augusto, Anselmi, Carlos, Azevedo, Guilherme S.A., Bittencourt, Marcio Sommer, Pianta, Diego Bromfman, Cabeda, Estevan, Carreira, Lara, Coelho, Igor, de Amorim Fernandes, Fernando, de Lorenzo, Andrea, Delgado, Roberta, Erthal, Fernanda, Fernandes, Fabio, Fernandes, Juliano, Ferreira de Souza, Thiago, Foppa, Murilo, Matos Alves, Wilson Furlan, Gontijo, Cibele, Gottlieb, Ilan, Grossman, Gabriel, Albernaz Siqueira, Maria Helena, Nomura, Cesar Higa, Koga, Katia Hiromoto, Lima, Ronaldo, Lopes, Rafael, Marçal Filho, Hugo Humberto, Masiero, Paulo, Mastrocola, Luiz, Menezes de Siqueira, Maria Eduarda, Mesquita, Claudio, Naves, Danilo, Penna, Filipe, Pinto, Ibraim, Rocha, Thércio, Rocha, Juliana Leal, Rodrigues, Alfredo, Salioni, Leila, Sanches, Adelina, Santos, Marcelo, Da Silva, Leonardo Sara, Schvartzman, Paulo, Matushita, Cristina Sebastião, Senra, Tiago, Silva, Marcelo, Soares, Carlos Eduardo, Spiro, Bernardo, Suaide Silva, Carlos Eduardo, Torres, Rafael, Monte, Guilherme Urpia, Vilela, Andrea, Villa, Alexandre Volney, Vitola, Joao, Voss, Themissa, Waltrick, Roberto, Zapparoli, Marcello, Naseer, Hamid, Garcheva-Tsacheva, Marina, Ouattara, Tiémégna Florence, Thou, Sarameth, Varoeun, Soley, Abikhzer, Gad, Beanlands, Rob, Chetrit, Michael, Dabreo, Dominique, Dennie, Carole, Friedrich, Matthias, Hafez, Mohmmed Nassoh, Hanneman, Kate, Miller, Robert, Oikonomou, Anastasia, Roifman, Idan, Small, Gary, Tandon, Vikas, Trivedi, Adwait, White, James, Zukotynski, Katherine, Alay, Rita, Concha, Carmen, Massardo, Teresa, Abad, Pedro, Anzola, Kelly, Arturo, Harold, Benitez, Luis, Cadena, Alberto, Zamudio, Carlos Caicedo, Calderón, Antonio, Gutierrez Villamil, Claudia T., Jaimes, Claudia, Londono, Juan L., Lopez, Nelson, Merlano-Gaitan, Sonia, Murgieitio-Cabrera, Ramon, Valencia, Manuel, Vergel, Damiana, Santamaria, Alejandro Zuluaga, Solis, Felix, Batinic, Tonci, Franceschi, Maja, Paar, Maja Hrabak, Prpic, Marina, Felipe Batista, Cuba: Juan, Cabrera, Lazaro Omar, Peix, Amalia, Peña, Yamilé, Rochela Vázquez, Luis Manuel, Ntalas, Ioannis, Kaminek, Milan, Kincl, Vladimir, Lang, Otto, Abdulla, Jawdat, Bøttcher, Morten, Busk, Martin, Geisler, Uka, Gormsen, Lars C., Hansson, Nicolaj, Hess, Søren, Hove, Jens, Jensen, Lars Thorbjoern, Jensen, Magnus T., Kragholm, Kristian Hay, Nørgaard, Bjarne L., Øvrehus, Kristian, Rasmussen, Jan, Rønnow Sand, Niels Peter, Sondergaard, Hanne, Zaremba, Tomas, Speckter, Herwin, Amores, Nelson, Velez, Mayra Sanchez, Alrahman, Taghreed Abd, Elsamad, Sherif Abd, Abdelfattah, Alia, Allam, Adel, Elkaffas, Sameh, Hassan, Mona, Hussein, Elshaymaa, Ibrahim, Ahmed, Kandeel, Ahmed, Ali, Mohamed Mandour, Shaaban, Mahmoud, Flores, Camila, Gómez Leiva, Verónica Vanesa, Liiver, Anita, Larikka, Martti, Uusitalo, Valtteri, Agostini, Denis, Berger, Clothilde, Dietz, Matthieu, Hyafil, Fabien, Ohana, Mickaël, Prigent, Kevin, Regaieg, Hamza, Sarda-Mantel, Laure, H-Ici, Darach O., Ayetey, Harold, Angelidis, George, Fragkaki, Christina, Fragkiadaki, Chrysoula, Georgoulias, Panagiotis, Koutelou, Maria, Kyrozi, Elena, Lama, Niki, Prassopoulos, Vassilis, Spartalis, Michael, Zaglavara, Theodora, Gonzalez, Carla, Gutierrez, Goleat, Maldonado, Alejandro, Martinez, Yassine, Kovács, Attila, Szilveszter, Bálint, Banthia, Nilesh, Bhat, Vivek, Bhatia, Mona, Choudhury, Partha, Chowdekar, Vijay Sai, Christopher, Johann, Garg, Tushar, Goyal, Naresh Kumar, Gupta, Ripen Kumar, Gupta, Abhishek, Hephzibah, Julie, Jain, Shashank, Krupa, Jesu, Kumar, Parveen, Kumar, Sukriti, Lalchandani, Arati, Mishra, Animesh, Mishra, Vivaswan Dutt, Mohan, Parul, Ozair, Ahmad, Pandey, Shivani, Parameswaran, Ramanathapuram, Patel, Chetan, Patel, Tapan, Patel, Shivani, Vimala, Leena Robinson, Kumar Sarangi, Dr Pradosh, Sengupta, Shantanu, Sethi, Arvind, Sharma, Amit, Sharma, Awadhesh Kumar, Sharma, Punit, Shrigiriwar, Apurva, Singh, Santosh, Singh, Harpreet, Sood, Ashwani, Verma, Atul, Vyas, Ajay, Soeriadi, Erwin Affandi, Bun, Edison, Hutomo, Febby, Syawaluddin, Hilman, Yudistiro, Ryan, Albadr, Amjed, Assadi, Majid, Emami, Farshad, Emami-Ardekani, Alireza, Farzanehfar, Saeed, Jafari, Ramezan, Manafi-Farid, Reyhaneh, Tajik, Maryam, Arnson, Yoav, Fuchs, Shmuel, Goldkorn, Ronen, Kennedy, John, Leitman, Marina, Shalev, Aryeh, Acampa, Wanda, Albano, Domenico, Alongi, Pierpaolo, Arnone, Gaspare, Assante, Roberta, Baritussio, Anna, Bauckneht, Matteo, Bianco, Francesco, Bonfiglioli, Rachele, Bovenzi, Francesco, Bruno, Isabella, Bruno, Andrea, Busnardo, Elena, Califaretti, Elena, Casoni, Roberta, Censullo, Vittorio, Chierichetti, Franca, Chiocchi, Marcello, Cittanti, Corrado, Clemente, Alberto, Cuocolo, Alberto, De Rimini, Maria Luisa, De Vincentis, Giuseppe, Della Tommasina, Veronica, Dellegrottaglie, Santo, Erba, Paola Anna, Evangelista, Laura, Faggi, Lara, Faragasso, Evelina, Florimonte, Luigia, Frantellizzi, Viviana, Gatti, Marco, Gaudiano, Angela, Gelardi, Fabrizia, Gerali, Alberto, Gimelli, Alessia, Guglielmo, Marco, Leccisotti, Lucia, Liga, Riccardo, Liguori, Carlo, Longo, Giampiero, Maffione, Margherita, Marcassa, Claudio, Matassa, Giovanni, Mele, Donato, Milan, Elisa, Mircoli, Luca, Paccagnella, Andrea, Pacella, Sara, Padovano, Federica, Pellegrini, Dario, Pergola, Valeria, Pugliese, Luca, Quartuccio, Natale, Rampin, Lucia, Ricci, Fabrizio, Rubini, Giuseppe, Russo, Vincenzo, Sambuceti, Gianmario, Scatteia, Alessandra, Sciagrà, Roberto, Spidalieri, Gianluca, Stefanelli, Antonella, Tedeschi, Carlo, Ventroni, Guido, Baugh, Dainia, Madu, Ernest, Aikawa, Tadao, Asano, Hiroshi, Fujimoto, Shinichiro, Fujise, Koichiro, Fukushima, Yoshimitsu, Fukuyama, Kae, Ichikawa, Yasutaka, Ideguchi, Reiko, Iguchi, Nobuo, Imai, Masamichi, Ishimura, Hayato, Isobe, Satoshi, Ito, Kimiteru, Izawa, Yu, Kadokami, Toshiaki, Kasai, Tokuo, Kato, Takao, Kawamoto, Takashi, Kiryu, Shigeru, Kumita, Shinichiro, Manabe, Osamu, Maruno, Hirotaka, Matsumoto, Naoya, Miyagawa, Masao, Moroi, Masao, Nagamachi, Shigeki, Nakajima, Kenichi, Nakazato, Ryo, Nanasato, Mamoru, Naya, Masanao, Norikane, Takashi, Ohta, Yasutoshi, Otomi, Yoichi, Otsuka, Hideki, Oyama-Manabe, Noriko, Saito, Masaki, Sarai, Masayoshi, Sato, Junichi, Sato, Daisuke, Shiraishi, Shinya, Takanami, Kentaro, Takehana, Kazuya, Taniguchi, Yasuyo, Teragawa, Hiroki, Tomizawa, Nobuo, Umeji, Kyoko, Wakabayashi, Yasushi, Yamada, Shinichiro, Yamazaki, Shinya, Yoneyama, Tatsuya, Rawashdeh, Mohammad, Dautov, Tairkhan, Makhdomi, Khalid, Abass, Mostafa, Garashi, Masoud, Siraj, Qaisar, Kalnina, Marika, Haidar, Mohamad, Komiagiene, Renata, Kviecinskiene, Giedre, Vajauskas, Donatas, Karim, Noor Khairiah A., Doucoure, Mady, Reichmuth, Luise, Samuel, Anthony, Dieng, Mohamed Lemine, Naojee, Ambedhkar Shantaram, Hernandez, Estrella Aguilera, Alducin Tellez, Cesar Rene, Alexánderson-Rosas, Erick, Barragan, Erika, Cabada, Manuel, Calderón, Daniel, Carvajal-Juarez, Isabel, Esparza, José, Gama-Moreno, Manlio Gerardo, Quinto, Virginia Garcia, Gonzalez, Nelsy Coromoto, Herrera-Zarza, Mary Carmen, Meave, Aloha, Medina Verdugo, Jesus Gregorio, Melendez, Gabriela, Morales Murguia, Rafael Humberto, Navarro Quiroz, Carlos Salvador, Ornelas, Mario, Preciado-Anaya, Andres, Preciado-Gutiérrez, Oscar Ulises, Puente, Adriana, Salazar, Aristóteles Ramírez, Rosales Uvera, Sandra Graciela, Rosales-Uvera, Sandra, Serna Macias, Jose Antonio, Sierra-Galan, Lilia, Sierra-Galan, Lilia M., Tirado Alderete, Juan Carlos, Vallejo, Enrique, Faraggi, Marc, Sereegotov, Erdenechimeg, Ben Rais, Nouzha, Alaoui, Nadia Ismaili, Kyiphyu, Thiri, Oo, Su Thet, Win, Soe Myat, Zar, Htin, Ghimire, Ram, Neupane, Madhu, Glaudemans, Andor, Slart, Riemer, Verschure, Derk, Allen, Berry, Edmond, John, Mckenzie, Clare, Tie, Stuart, Van Pelt, Niels, Worthington, Kirsten, Young, Calum, Soli, Idrissa Adamou, Kana, Shehu, Onubogu, Uchenna, Sani, Mahmoud, Bråten, Anders Tjellaug, Jørgensen, Arve, Vassbotn, Hanne-Elin, Al Dhuhli, Humoud, Jawa, Zabah, Tag, Naima, Fatima, Shazia, Imran, Muhammad Babar, Younis, Muhammad Numair, Saadullah, Mohammad, Malo, Yariela Herrera, Lenturut-Katal, Dora, Castillo, Manuel, Ortellado, José, Akhter, Afroza, Cader, F. Aaysha, Hussain, Raihan, Khan, Saidur Rahman, Mandal, Tapati, Nasreen, Faria, An, Yunqiang, Cao, Dianbo, Gong, Lianggeng, Hou, Yang, Jia, Chongfu, Li, Tao, Li, Caiying, Liu, Hui, Liu, Wenya, Liu, Jinkang, Lu, Bin, Ng, Ming-Yen, Shi, Heshui, Tang, Chunxiang, Wang, Ximing, Wang, Zhaoqian, Wang, Yining, Wu, Jiang, Yi, Yan, Yuan, Li, Zhang, Tong, Zhang, Longjiang, Chavez, Edith, Cruz, Carlos, Llontop, Christian, Morales, Rosanna, Abrihan, Paz, Bustos-Barroso, Asela, Duldulao-Ogbac, Michele, Eduarte, Christopher, Obaldo, Jerry, Quinon, Alvin, San Juan, Belinda, San Juan, Carlo Joe, Sauler-Gomez, Marie Rhiamar, Uy, Mila, Kostkiewicz, Magdalena, Kunikowska, Jolanta, Teresinska, Anna, Urbanik, Tomasz, Bettencourt, Nuno, Fontes-Carvalho, Ricardo, Gavina, Cristina, Gonçalves, Lino, Macedo, Filipe, Moreno, Nuno, Sousa, Carla, Timoteo, Ana Teresa, Vidigal, Maria João, Al Heidous, Mahmoud, Ramanathan, Subramaniyan, Arnous, Samer, Aytani, Said, Byrne, Angela, Gleeson, Tadhg, Kerins, David, O'Brien, Julie, Bang, Ji-In, Bom, Henry, Cheon, Miju, Cheon, Gi Jeong, Cho, Sang-Geon, Hong, Chae Moon, Jeong, Yong Hyu, Kang, Won Jun, Kang, Yeon-Koo, Kim, Ji-Young, Oh, So Won, So, Young, Song, Ho-Chun, Won, Kyoung Sook, Yoo, Soo Woong, Mitevska, Irena, Vavlukis, Marija, Salobir, Barbara Gužic, Štalc, Monika, Benedek, Theodora, Pop, Marian, Stan, Claudiu, Ansheles, Alexey, Dariy, Olga, Gagarina, Nina, Itskovich, Irina, Karalkin, Anatoliy, Kokov, Alexander, Marina, Gulya, Migunova, Ekaterina, Pospelov, Viktor, Ryzhkova, Daria, Sayfullina, Guzaliya, Sergienko, Vladimir, Shurupova, Irina, Sinitsyn, Valentin, Vakhromeeva, Margarita, Valiullina, Nailia, Zavadovsky, Konstantin, Zhuravlev, Kirill, Abazid, Rami, Al Garni, Turki, Alasnag, Mirvat, Aljizeeri, Ahmed, Amer, Hamid, Amro, Ahmad, Hamdy, Hesham, Smettei, Osama, Saranovic, Dragana Sobic, Vlajkovic, Marina, Keng, Felix, See, Jason, Berecova, Zuzana, Mistinova, Jana Polakova, Evbuomwan, Osayande, Govender, Nerisha, Hack, Jonathan, Hadebe, Bawinile, Hlongwa, Khanyisile, Kaplan, Mitchell, Lakhi, Hoosen, Milos, Katarina, Modiselle, Moshe, More, Stuart, Muambadzi, Ntanganedzeni, Scholtz, Leonie, Barreiro-Perez, Manuel, Blanco, Isabel, Broncano, Jordi, Camarero, Alicia, Casáns-Tormo, Irene, De Haro, Javier, Flotats, Albert, García, Elia, Mendiguchia, Ceferino Gutierrez, Jimenez-Heffernan, Amelia, Leta, Ruben, Diaz, Javier Lopez, Vega, Luis Lumbreras, Manovel-Sánchez, Ana, Monzonis, Amparo Martinez, Patrut, Bianca, Pubul, Virginia, Perez, Ricardo Ruano, Zeidan, Nahla, Nanayakkara, Damayanthi, Suliman, Ahmed, Engblom, Henrik, Murtadha, Mustafa, Ostenfeld, Ellen, Simonsson, Magnus, Alkadhi, Hatem, Buechel, Ronny Ralf, Burger, Peter, Gräni, Christoph, Kamani, Christel, Kawel-Böhm, Nadine, Klaeser, Bernd, Manka, Robert, Prior, John, Kaewchur, Tawika, Khiewvan, Benjapa, Kositwattanarerk, Arpakorn, Namwongprom, Sirianong, Thientunyakit, Tanyaluck, Sayman, Haluk Burcak, Yüksel, Mahmut, Sebikali, Mugisha Julius, Okello, Emmy, Korol, Pavlo, Noverko, Iryna, Satyr, Maryna, Ahmad, Tahir, Alfakih, Khaled, Andrade, Ivo, Buckingham, Susan, Bularga, Anda, Carpenter, John-Paul, Cole, Graham, Cusack, David, David, Sarojini, Davis, Patrick, Fairbairn, Timothy, Ghosh, Arjun, Ramkumar, Prasad Guntur, Hamilton, Mark, Haque, Faisal, Hudson, Benjamin, Johnstone, Annette, Karthikeyan, V.J., Kay, Mike, Khan, Mohammad Ali, Kitt, Jamie, Low, Chen Sheng, Mcalindon, Elisa, Mccreavy, David, Morrissey, Brian, Motwani, Manish, Na, Dilip, Nicol, Edward, Patel, Dilip, Rodrigues, Jonathan, Rofe, Chris, Schofield, Rebecca, Semple, Thomas, Sheikh, Azeem, Sinha, Apurva, Subedi, Deepak, Topping, William, Tweed, Katherine, Underwood, Stephen Richard, Weir-Mccall, Jonathan, Zuhairy, Hamed, Abbasi, Taimur, Abohashem, Shady, Abramson, Sandra, Al-Mallah, Mouaz, Kumar, Mohan Ashok, Balmer-Swain, Mallory, Berman, Daniel, Bernheim, Adam, Bhatti, Sabha, Biederman, Robert, Bieging, Erik, Bingham, Scott, Bloom, Stephen, Blue, Sean, Borges, Andressa, Branch, Kelley, Bravo, Paco, Buddhe, Sujatha, Budoff, Matthew, Bullock-Palmer, Renée, Cahill, Michael, Candela, Candace, Cao, Jane, Chatterjee, Saurav, Chatzizisis, Yiannis, Chaudhuri, Nita Ray, Cheezum, Michael, Chelliah, Anjali, Chen, Tiffany, Chen, Marcus, Chen, Lu, Chokshi, Aalap, Chung, Jina, Danciu, Sorin, DeSisto, William, Dilorenzo, Michael, Doukky, Rami, Duvall, William, Ferencik, Maros, Foster, Cameron, Fuisz, Anthon, Gannon, Michael, German, David, Gerson, Myron, Geske, Jeffrey, Hage, Fadi, Haider, Agha, Haider, Sofia, Hamirani, Yasmin, Hassen, Karen, Hendel, Robert, Henkel, Jacqueline, Horgan, Stephen, Hyun, Mark, Janardhanan, Rajesh, Jerome, Scott, Kalra, Dinesh, Kassop, David, Kinkhabwala, Mona, Kinzfogl, George, Koch, Bernard, Koweek, Lynne, Krepp, Joseph, Kwon, Younghoon, Layer, Jay, Lesser, John, Leung, Steve, Lisske, Bernadette, Magurany, Kathleen, Markowitz, Jeremy, Mccullough, Brenda, Moalemi, Azita, Moffitt, Chanan, Montanez, Juan, Moore, Warren, Morayati, Shamil, Mossa-Basha, Mahmud, Mrsic, Zorana, Murthy, Venkatesh, Nagpal, Prashant, Nelson, Katarina, Nijjar, Prabhjot, O’Quinn, Rupal, Passen, Edward, Patel, Toral, Patil, Pravin, Pursnani, Amit, Quachang, Nancy, Rabbat, Mark, Ranjan, Pragya, Lozano, Patricia Rodriguez, Schemmer, Mary, Seifried, Rebecca, Shah, Nishant, Shah, Amee, Shanbhag, Sujata, Sharma, Gaurav, Skotnicki, Robert, Sobczak, Michael, Soman, Prem, Sorrell, Vincent, Srichai, Monvadi, Streeter, Jim, Strickland, Leah, Suliman, Suliman, Tebyanian, Naghmeh, Thomas, Dustin, Thompson, Randall, Uretsky, Seth, Vallurupalli, Srikanth, Vandyck-Acquah, Marian, Verma, Vikas, Villines, Todd, Weinstein, Joseph, Wolinsky, David, Zareba, Karolina, Zgaljardic, Michael, Beretta, Mario, Ferrando, Rodolfo, Kapitan, Miguel, Mut, Fernando, Djuraev, Omoa, Rozikhodjaeva, Gulnora, Vera, Luisa, Duc, Binh Duong, Nguyen, Xuan Canh, Hiep Nguyen, Phuoc Minh, Hirschfeld, Cole, Choi, Andrew D., Ansheles, Alexey A., Kudo, Takashi, Bucciarelli-Ducci, Chiara, Nørgaard, Bjarne Linde, Maurovich-Horvat, Pál, Louw, Lizette, Allam, Adel H., and Narula, Jagat

Published
2022
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15. Effects of Antihypertensive Treatment on Left and Right Ventricular Global Longitudinal Strain and Diastolic Parameters in Patients with Hypertension and Obstructive Sleep Apnea: Randomized Clinical Trial of Chlorthalidone plus Amiloride vs. Amlodipine

Author

Jorge, Juliano A., primary, Foppa, Murilo, additional, Santos, Angela B. S., additional, Cichelero, Fábio T., additional, Martinez, Denis, additional, Lucca, Marcelo B., additional, de Oliveira, Geórgia P. F., additional, Fuchs, Flávio D., additional, and Fuchs, Sandra C., additional

Published
2023
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21. Volume de Gordura Epicárdica está Associada com Disfunção Endotelial, mas Não com Calcificação Coronariana: Do ELSA-Brasil

Author

Martins, Karina P. M. P., primary, Barreto, Sandhi M., additional, Bos, Daniel, additional, Pedrosa, Jesiana, additional, Azevedo, Douglas R. M., additional, Araújo, Larissa Fortunato, additional, Foppa, Murilo, additional, Duncan, Bruce B., additional, Ribeiro, Antonio Luiz P., additional, and Brant, Luisa C. C., additional

Published
2022
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26. Parâmetros Ecocardiográficos Simples são Fortes Preditores de Risco Cardiovascular em Indivíduos Assintomáticos: Coorte Elsa-Brasil

Author

Fernandes, Luciana Pereira, primary, Almeida, Maria da Conceição Chagas de, additional, Matos, Sheila Alvim de, additional, Campos, Ana Clara Paixão, additional, Câmara, Edmundo José Nassri, additional, Foppa, Murilo, additional, Ribeiro, Antônio Luiz Pinho, additional, Barreto, Sandhi Maria, additional, and Aras, Roque, additional

Published
2022
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27. Volume de Gordura Epicárdica está Associada com Disfunção Endotelial, mas Não com Calcificação Coronariana: From the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

Author

Martins, Karina P.M.P., Barreto, Sandhi M., Bos, Daniel, Pedrosa, Jesiana, Azevedo, Douglas R.M., Araújo, Larissa Fortunato, Foppa, Murilo, Duncan, Bruce B., Ribeiro, Antonio Luiz P., Brant, Luisa C.C., Epidemiology, and Radiology & Nuclear Medicine

Abstract

Background: The increase in epicardial fat volume (EFV) is related to coronary artery disease (CAD), independent of visceral or subcutaneous fat. The mechanism underlying this association is unclear. Coronary artery calcium (CAC) score and endothelial dysfunction are related to coronary events, but whether EFV is related to these markers needs further clarification. Objectives: To evaluate the association between automatically measured EFV, cardiovascular risk factors, CAC, and endothelial function. Methods: In 470 participants from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) with measures of EFV, CAC score and endothelial function, we performed multivariable models to evaluate the relation between cardiovascular risk factors and EFV (response variable), and between EFV (explanatory variable) and endothelial function variables or CAC score. Two-sided p 0. Conclusion: Higher EFV was associated with impaired endothelial function, but not with CAC. The results suggest that EFV is related to the development of CAD through a pathway different from the CAC pathway, possibly through aggravation of endothelial dysfunction and microvascular disease.

Published
2022

28. Epicardial Fat Volume Is Associated with Endothelial Dysfunction, but not with Coronary Calcification: From the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

Author

Martins, Karina PMP, Barreto, Sandhi M, Bos, Daniel, Pedrosa, Jesiana, Azevedo, Douglas RM, Araujo, Larissa Fortunato, Foppa, Murilo, Duncan, Bruce B, Ribeiro, Antonio Luiz P, and Brant, Luisa CC

Abstract

BACKGROUND: The increase in epicardial fat volume (EFV) is related to coronary artery disease (CAD), independent of visceral or subcutaneous fat. The mechanism underlying this association is unclear. Coronary artery calcium (CAC) score and endothelial dysfunction are related to coronary events, but whether EFV is related to these markers needs further clarification. OBJECTIVES: To evaluate the association between automatically measured EFV, cardiovascular risk factors, CAC, and endothelial function. METHODS: In 470 participants from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) with measures of EFV, CAC score and endothelial function, we performed multivariable models to evaluate the relation between cardiovascular risk factors and EFV (response variable), and between EFV (explanatory variable) and endothelial function variables or CAC score. Two-sided p 0. CONCLUSION: Higher EFV was associated with impaired endothelial function, but not with CAC. The results suggest that EFV is related to the development of CAD through a pathway different from the CAC pathway, possibly through aggravation of endothelial dysfunction and microvascular disease. ispartof: ARQUIVOS BRASILEIROS DE CARDIOLOGIA vol:119 issue:6 pages:912-920 ispartof: location:Brazil status: published

Published
2022

32. Contributors

Author

Abbott, Brian G., primary, Abbott, J. Dawn, additional, Adams, David H., additional, Al-Atassi, Talal, additional, Al-Dameh, Ali, additional, Allen, Mark S., additional, Altorki, Nasser K., additional, Anand, Jatin, additional, Anderson, Robert H., additional, Anraku, Masaki, additional, Anyanwu, Anelechi C., additional, Arora, Amit, additional, Austin, Erle H., additional, Awtry, Eric H., additional, Bacha, Emile A., additional, Backhus, Leah M., additional, Bagai, Jayant, additional, Baillot, Richard, additional, Baird, Christopher W., additional, Barron, David J., additional, Bavaria, Joseph E., additional, Bernal, Jose M., additional, Bianco, Valentino J., additional, Bichell, David P., additional, Birgisson, Sigurbjorn, additional, Blackburn, Nick J.R., additional, Bonatti, Johannes, additional, Boodhwani, Munir, additional, Bove, Edward L., additional, Brawn, William J., additional, Brizard, Christian P., additional, Brothers, Julie A., additional, Brown, Lisa M., additional, Bryant, Ayesha S., additional, Burkhart, Harold M., additional, Caldarone, Christopher A., additional, Cannon, Jeremy W., additional, Carr, Justine M., additional, Castelvecchio, Serenella, additional, Castillo, Javier G., additional, Cecchin, Frank, additional, Cerfolio, Robert J., additional, Chahine, A. Alfred, additional, Chaikof, Elliot L., additional, Chan, Vincent, additional, Chaudhry, Sunit-Preet, additional, Chen, Frederick Y., additional, Chen, Stuart H., additional, Cheng, Aaron M., additional, Chien, Victor, additional, Chin, Alvin J., additional, Chin, Cynthia S., additional, Chiu, Peter, additional, Cleveland, Joseph C., additional, Cohn, Lawrence H., additional, Cohn, William E., additional, Colson, Yolonda L., additional, Colucci, Wilson S., additional, Cook, Andrew C., additional, Coselli, Joseph S., additional, Crawford, Todd C., additional, Culligan, Melissa, additional, Dagenais, François, additional, Damiano, Ralph J., additional, D'Amico, Thomas A., additional, Dartevelle, Philippe G., additional, David, Tirone E., additional, D'Cunha, Jonathan, additional, de la Cruz, Kim I., additional, Dearani, Joseph A., additional, DeArmond, Daniel T., additional, del Nido, Pedro J., additional, DeMeester, Tom R., additional, Demers, Philippe, additional, Demmy, Todd L., additional, Dexter, Elisabeth U., additional, Dhupar, Rajeev, additional, DiNardo, James A., additional, Doyle, Thomas P., additional, Ehsan, Afshin, additional, Khoury, Gebrine El, additional, Ellis, Ethan R., additional, Elmadhun, Nassrene Y., additional, Emani, Sitaram M., additional, Erasmus, Jeremy J., additional, Fauza, Dario O., additional, Fein, Adam S., additional, Fiedler, Amy G., additional, Foppa, Murilo, additional, Freeman, Rosario V., additional, Friedberg, Joseph, additional, Friscia, Michael, additional, Fynn-Thompson, Francis, additional, Gaynor, J. William, additional, Ge, Liang, additional, Geva, Tal, additional, Gheewala, Neil M., additional, Gillinov, A. Marc, additional, Glower, Donald D., additional, Goldstone, Andrew B., additional, Groth, Shawn S., additional, Grover, Frederick L., additional, Guccione, Julius, additional, Ha, Richard, additional, Hammon, John W., additional, Hanna, Jennifer M., additional, Harrison, David G., additional, Hauser, Thomas H., additional, Henn, Matthew C., additional, Hirsch-Romano, Jennifer C., additional, Hoang, Chuong D., additional, Hofstetter, Wayne L., additional, Honjo, Osami, additional, Huynh, Tam T., additional, Bravo, Carlos E., additional, Iturra, Sebastian, additional, Jacobs, Jeffrey P., additional, Jacobs, Marshall L., additional, Jaklitsch, Michael T., additional, Jamieson, Stuart W., additional, Jarrar, Doraid, additional, Jarrett, Craig M., additional, Jones, David R., additional, Josephson, Mark E., additional, Joventino, Lilian P., additional, Juraszek, Amy L., additional, Kachala, Stefan S., additional, Kaiser, Larry R., additional, Kanter, Kirk R., additional, Karamichalis, John M., additional, Kaza, Aditya K., additional, Kemp, Clinton D., additional, Kernstine, Kemp H., additional, Keshavamurthy, Suresh, additional, Keshavjee, Shaf, additional, Kozik, Deborah J., additional, Laham, Roger J., additional, Landzberg, Michael J., additional, Lawrance, Christopher P., additional, Lee, Lawrence S., additional, LeMaire, Scott A., additional, Levitsky, Sidney, additional, Levy, Jerrold H., additional, Linden, Philip A., additional, Liptay, Michael J., additional, Litle, Virginia R., additional, Rito, Mauro Lo, additional, Luketich, James D., additional, Lytle, Bruce W., additional, Madani, Michael, additional, Mahmood, Feroze, additional, Mallidi, Hari R., additional, Mangi, Abeel A., additional, Manning, Warren J., additional, Marom, Edith M., additional, Marshall, Audrey C., additional, Martinez, Mauricio Perez, additional, Mascio, Christopher E., additional, Mason, David P., additional, Mathisen, Douglas J., additional, Mattox, Kenneth L., additional, Matyal, Robina, additional, McCully, James D., additional, McKenna, Robert J., additional, McNamee, Ciaran, additional, McNeil, Jeffrey D., additional, Menicanti, Lorenzo, additional, Mestres, Carlos A., additional, Mettler, Bret A., additional, Meyers, Bryan Fitch, additional, Mick, Stephanie, additional, Mihaljevic, Tomislav, additional, Milano, Carmelo A., additional, Miller, D. Craig, additional, Miller, Daniel L., additional, Miller, Meagan M., additional, Mitchell, John D., additional, Montealegre-Gallegos, Mario, additional, Moores, Neal G., additional, Murphy, Charles E., additional, Murthy, Raghav A., additional, Murthy, Sudish C., additional, Mussot, Sacha, additional, Naka, Yoshifumi, additional, Nathan, Meena, additional, Newman, Kurt D., additional, Nwogu, Chukwumere, additional, Odegard, Kirsten C., additional, Oh, Daniel S., additional, Ohye, Richard G., additional, Onaitis, Mark W., additional, Ostojic, Aleksandra, additional, Ott, Harald C., additional, Ouzounian, Maral, additional, Owais, Khurram, additional, Padalino, Massimo, additional, Papadakis, Konstantinos, additional, Patterson, G.A., additional, Patz, Edward F., additional, Paul, Subroto, additional, Pennathur, Arjun, additional, Perry, Yaron, additional, Piana, Robert N., additional, Pigula, Frank A., additional, Pinto, Duane S., additional, Pomar, Jose L., additional, Preventza, Ourania, additional, Pua, Bradley, additional, Puri, Varun, additional, Quinonez, Luis, additional, Raja, Siva, additional, Ratcliffe, Mark, additional, Reardon, Michael J., additional, Reilly, John J., additional, Reyes, Karl G., additional, Rice, Thomas W., additional, Robbins, Robert C., additional, Rocco, Gaetano, additional, Rubens, Fraser D., additional, Ruel, Marc, additional, Rusch, Valerie W., additional, Sabe, Ashraf A., additional, Said, Sameh M., additional, Samson, Pamela P., additional, Sanders, Stephen P., additional, Sarin, Eric L., additional, Schaff, Hartzell V., additional, Schaheen, Lara W., additional, Seder, Christopher W., additional, Sellke, Frank W., additional, Sepesi, Boris, additional, Shahani, Rohit, additional, Shamberger, Robert C., additional, Shapira, Oz M., additional, Shay, Steven S., additional, Shrager, Joseph B., additional, Si, Ming-Sing, additional, Singh, Steve K., additional, Smith, Peter K., additional, Sodha, Neel R., additional, Solaro, R. John, additional, Soukiasian, Harmik J., additional, Spurlock, David, additional, Stellin, Giovanni, additional, Stiles, Brendon M., additional, Straznicka, Michaela, additional, Stump, David A., additional, Sugarbaker, David J., additional, Suuronen, Erik J., additional, Svensson, Lars G., additional, Swanson, Scott J., additional, Szeto, Wilson Y., additional, Taghavi, Sharven, additional, Takayama, Hiroo, additional, Takeda, Koji, additional, Thiagarajan, Ravi R., additional, Thistlethwaite, Patricia A., additional, Thourani, Vinod H., additional, Toeg, Hadi D., additional, Tong, Michael Z., additional, Truesdell, Alexander G., additional, Tsai, Peter I., additional, Urschel, Harold C., additional, Valente, Anne Marie, additional, Vallabhajosyula, Prashanth, additional, Velotta, Jeffrey B., additional, Vida, Vladimiro, additional, Vlahakes, Gus J., additional, Voisine, Pierre, additional, Wall, Matthew J., additional, Walsh, Garrett L., additional, Walters, Dustin M., additional, Wei, Benjamin, additional, Welsby, Ian J., additional, Westfall, Margaret V., additional, Wiener, Daniel C., additional, Wilcox, Benson R., additional, Williams, Judson B., additional, Wilson, Jay M., additional, Woo, Y. Joseph, additional, Wood, Douglas E., additional, Wylie, John V., additional, Yang, Stephen C., additional, Yendamuri, Sai, additional, Yeon, Susan B., additional, and Zimetbaum, Peter J., additional

Published
2016
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44. Red wine with the noon meal lowers post-meal blood pressure: a randomized trial in centrally obese, hypertensive patients

Author

Foppa, Murilo, Fuchs, Flavio D., Preissler, Lisangela, Andrighetto, Andre, Rosito, Guido A., and Duncan, Bruce B.

Subjects
Heart diseases -- Prevention, Alcohol -- Health aspects, Red wines -- Health aspects, Alcohol, Denatured -- Health aspects, Health, Psychology and mental health, Prevention, Health aspects
Abstract

Objective: Despite being recognized as a cause of hypertension at higher doses, consumption of lesser amounts of alcohol appears to protect against cardiovascular disease and acutely reduces blood pressure. We tested the hypothesis that two glasses of red wine, taken together with the noon meal, would cause postprandial reduction in blood pressure in hypertensive individuals. Method: Thirteen (8 female) middle-aged, centrally obese, hypertensive and otherwise healthy participants received, in an open randomized crossover experiment, red wine (250 ml; 23 g of ethanol) and a placebo equivalent, together with a standardized lunch. Blood pressure was measured with 24-hour ambulatory monitoring. Results: Wine with the meal produced a mean (SD) reduction of 5.3 (7.66) mmHg in postprandial blood pressure (p = .03), which persisted for most of the remaining daytime interval. The maximal blood pressure reduction was 8.5 (11.84) mmHg, occurring 3 hours after intervention (p = .02). In addition, nocturnal dipping in systolic blood pressure was lessened during the wine intervention period (5.3 [10.19] vs 11.1 [8.08] mmHg; p = .03). Conclusions: Ingestion of 250 ml of red wine, together with the noon meal, resulted in reduction of the postprandial blood pressure of centrally obese, hypertensive subjects. The effect lasted throughout most of the remaining daytime interval and appeared to modify the usual blood pressure variation pattern. (J. Stud. Alcohol 63:247-251, 2002), LARGE PROSPECTIVE observational studies suggest that moderate alcohol consumption protects against coronary heart disease (Maclure, 1993; Thun et al., 1997). Despite evidence suggesting that a considerable part of this effect [...]

Published
2002

47. RISK FACTORS FOR CORONARY ARTERY CALCIUM INCIDENCE AND PROGRESSION IN AN ETHNICALLY DIVERSE COHORT

Author

Cardoso, Rhanderson, primary, Generoso, Giuliano, additional, Staniak, Henrique, additional, Foppa, Murilo, additional, Duncan, Bruce, additional, Pereira, Alexandre, additional, Blaha, Michael, additional, Blankstein, Ron, additional, Nasir, Khurram, additional, Bensenor, Isabela, additional, Lotufo, Paulo, additional, and Bittencourt, Marcio, additional

Published
2020
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48. Diuréticos são similares à Losartana na avaliação ecocardiográfica de lesão a órgãos-alvo no estágio I da hipertensão : estudo PREVER-Treatment

Author

Bertoluci, Carolina, Foppa, Murilo, Santos, Ângela Barreto Santiago, Fuchs, Sandra Cristina Pereira Costa, and Fuchs, Flávio Danni

Subjects
Calcium channel, Echocardiography, Angiotensin-converting enzyme inhibitors, Hypertension, Blood pressure, Diuréticos, Anihypertensive agents, Losartan, Ecocardiografia, Hipertensão
Abstract

A terapia de redução da pressão arterial (PA) melhora os parâmetros do ventrículo esquerdo (VE) na lesão a órgãos-alvo causada pela condição hipertensiva na hipertensão de estágio II; no entanto, se existem ou não diferenças relacionadas à classe de medicamentos nos parâmetros ecocardiográficos de pacientes com hipertensão estágio I é menos frequentemente estudado. No estudo PREVER-treatment, em que indivíduos com hipertensão estágio I foram randomizados para tratamento com diuréticos (clortalidona/amilorida) ou losartana, 110 participantes aceitaram participar de um subestudo, no qual foram realizados ecocardiogramas bidimensionais basais e após 18 meses de tratamento anti-hipertensivo. Como no estudo geral, a redução da PA sistólica foi semelhante com diuréticos ou com losartana. Os parâmetros ecocardiográficos mostraram pequenas mas significativas alterações em ambos os grupos de tratamento, com um remodelamento favorável do VE com tratamento anti-hipertensivo por 18 meses, quando a pressão arterial alvo foi atingida com clortalidona/amilorida ou com losartana como estratégia inicial de tratamento. Em conclusão, mesmo na hipertensão estágio I, a redução da pressão arterial está associada à melhora nos parâmetros ecocardiográficos tanto com o uso de diuréticos ou losartana como primeiro esquema de tratamento farmacológico. Blood pressure (BP)-lowering therapy improves left ventricular (LV) parameters of hypertensive target-organ damage in stage II hypertension, but whether there is a drug-class difference in echocardiographic parameters in stage I hypertension patients is less often studied. In the PREVER treatment study, where individuals with stage I hypertension were randomized for treatment with diuretics (chlorthalidone/amiloride) or losartan, 110 participants accepted to participate in a sub-study, where two-dimensional echocardiograms were performed at baseline and after 18 months of antihypertensive treatment. As in the general study, systolic BP reduction was similar with diuretics or with losartan. Echocardiographic parameters showed small but significant changes in both treatment groups, with a favorable LV remodeling with antihypertensive treatment for 18 months when target blood pressure was achieved either with chlorthalidone/amiloride or with losartan as the initial treatment strategy. In conclusion, even in stage I hypertension, blood pressure reduction is associated with improvement in echocardiographic parameters, either with diuretics or losartan as first-drug regimens.

Published
2019

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