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1. Does Studying Latin in Secondary Education Predict Study Achievement in Academic Higher Education?

Author

Cathy Hauspie, Stijn Schelfhout, Nicolas Dirix, Lot Fonteyne, Mark Janse, Arnaud Szmalec, Alexandra Vereeck, and Wouter Duyck

Abstract

Studying Latin in secondary education is still widespread in Europe and believed to result in cognitive benefits, even beyond the linguistic domain. In this study we explored the relation between such study and later academic achievement in higher education (N = 1,898). First, we demonstrated that Latin students exhibit increased levels of study achievement in higher education, particularly in study programs other than those covering science, technology, engineering, and mathematics (STEM). Second, we explored where the instruction of Latin was a significant predictor in models of academic achievement, explaining incremental variance over 21 other cognitive, attitudinal, and demographic variables. Latin instruction was included as a variable in the prediction models in 42% of the programs (mainly in the non-STEM ones), but the incremental predictive validity was substantial only in the linguistic programs. Our results highlight how the study of Latin can be a valuable predictor of academic achievement in other study fields.

Published
2024
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7. Management of Patients with Advanced Prostate Cancer. Report from the 2024 Advanced Prostate Cancer Consensus Conference (APCCC)

Author

Gillessen, Silke, Turco, Fabio, Davis, Ian D., Efstathiou, Jason A., Fizazi, Karim, James, Nicholas D., Shore, Neal, Small, Eric, Smith, Matthew, Sweeney, Christopher J., Tombal, Bertrand, Zilli, Thomas, Agarwal, Neeraj, Antonarakis, Emmanuel S., Aparicio, Ana, Armstrong, Andrew J., Bastos, Diogo Assed, Attard, Gerhardt, Axcrona, Karol, Ayadi, Mouna, Beltran, Himisha, Bjartell, Anders, Blanchard, Pierre, Bourlon, Maria T., Briganti, Alberto, Bulbul, Muhammad, Buttigliero, Consuelo, Caffo, Orazio, Castellano, Daniel, Castro, Elena, Cheng, Heather H., Chi, Kim N., Clarke, Caroline S., Clarke, Noel, de Bono, Johann S., De Santis, Maria, Duran, Ignacio, Efstathiou, Eleni, Ekeke, Onyeanunam N., El Nahas, Tamer I.H., Emmett, Louise, Fanti, Stefano, Fatiregun, Omolara A., Feng, Felix Y., Fong, Peter C.C., Fonteyne, Valerie, Fossati, Nicola, George, Daniel J., Gleave, Martin E., Gravis, Gwenaelle, Halabi, Susan, Heinrich, Daniel, Herrmann, Ken, Hofman, Michael S., Hope, Thomas A., Horvath, Lisa G., Hussain, Maha H.A., Jereczek-Fossa, Barbara Alicja, Jones, Robert J., Joshua, Anthony M., Kanesvaran, Ravindren, Keizman, Daniel, Khauli, Raja B., Kramer, Gero, Loeb, Stacy, Mahal, Brandon A., Maluf, Fernando C., Mateo, Joaquin, Matheson, David, Matikainen, Mika P., McDermott, Ray, McKay, Rana R., Mehra, Niven, Merseburger, Axel S., Morgans, Alicia K., Morris, Michael J., Mrabti, Hind, Mukherji, Deborah, Murphy, Declan G., Murthy, Vedang, Mutambirwa, Shingai B.A., Nguyen, Paul L., Oh, William K., Ost, Piet, O’Sullivan, Joe M., Padhani, Anwar R., Parker, Chris, Poon, Darren M.C., Pritchard, Colin C., Rabah, Danny M, Rathkopf, Dana, Reiter, Robert E., Renard-Penna, Raphaele, Ryan, Charles J., Saad, Fred, Sade, Juan Pablo, Sandhu, Shahneen, Sartor, Oliver A., Schaeffer, Edward, Scher, Howard I., Sharifi, Nima, Skoneczna, Iwona A., Soule, Howard R., Spratt, Daniel E., Srinivas, Sandy, Sternberg, Cora N., Suzuki, Hiroyoshi, Taplin, Mary-Ellen, Thellenberg-Karlsson, Camilla, Tilki, Derya, Türkeri, Levent N., Uemura, Hiroji, Ürün, Yüksel, Vale, Claire L., Vapiwala, Neha, Walz, Jochen, Yamoah, Kosj, Ye, Dingwei, Yu, Evan Y., Zapatero, Almudena, and Omlin, Aurelius

Published
2025
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8. A unified strategy to focal brachytherapy incorporating transperineal biopsy, image fusion, and real-time implantation with and without rectal spacer simulated in prostate phantoms

Author

Ben G.L. Vanneste, Basile Skouteris, Luis Campos Pinheiro, Robert Voncken, Evert J. Van Limbergen, Ludy Lutgens, Valérie Fonteyne, Charles Van Praet, Nicolaas Lumen, Rendi Sheu, Richard Stock, and Nelson N. Stone

Subjects
prostate cancer, brachytherapy, focal, transperineal biopsy, image fusion, toxicity reduction, rectum spacer, Medicine
Published
2024
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9. Rotational complexity increases cropping system output under poorer growing conditions

Author

Bybee-Finley, K. Ann, Muller, Katherine, White, Kathryn E., Cavigelli, Michel A., Han, Eunjin, Schomberg, Harry H., Snapp, Sieglinde, Viens, Frederi, Correndo, Adrian A., Deiss, Leonardo, Fonteyne, Simon, Garcia y Garcia, Axel, Gaudin, Amélie C.M., Hooker, David C., Janovicek, Ken, Jin, Virginia, Johnson, Gregg, Karsten, Heather, Liebman, Matt, McDaniel, Marshall D., Sanford, Gregg, Schmer, Marty R., Strock, Jeffrey, Sykes, Virginia R., Verhulst, Nele, Wilke, Brook, and Bowles, Timothy M.

Published
2024
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12. PEACE V—Salvage Treatment of OligoRecurrent nodal prostate cancer Metastases (STORM): Acute Toxicity of a Randomized Phase 2 Trial

Author

Ost, Piet, Siva, Shankar, Brabrand, Sigmund, Dirix, Piet, Liefhooghe, Nick, Otte, François-Xavier, Gomez-Iturriaga, Alfonso, Everaerts, Wouter, Shelan, Mohamed, Conde-Moreno, Antonio, López Campos, Fernando, Papachristofilou, Alexandros, Guckenberger, Matthias, Scorsetti, Marta, Zapatero, Almudena, Villafranca Iturre, Ana-Elena, Eito, Clara, Couñago, Felipe, Muto, Paolo, Van De Voorde, Lien, Mach, Nicolas, Bultijnck, Renée, Fonteyne, Valérie, Moon, Daniel, Thon, Kristian, Mercier, Carole, Achard, Vérane, Stellamans, Karin, Goetghebeur, Els, Reynders, Dries, and Zilli, Thomas

Published
2024
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14. Health-related quality of life in men with oligometastatic prostate cancer following metastases-directed stereotactic body radiotherapy: Real-world data from the E2-RADIatE OligoCare cohort

Author

Bultijnck, Renée, Van Hemelrijck, Mieke, Fonteyne, Valérie, Livi, Lorenzo, Jereczek-Fossa, Barbara Alicja, Hemmatazad, Hossein, Mayinger, Michael, Peulen, Heike, Verbeke, Luc, Ramella, Sara, Castro, Pablo, Tsoutsou, Pelagia, Stellamans, Karin, Shaukat, Adnan, Orazem, Miha, Jeene, Paul, Braam, Pètra, Verkooijen, Helena, Simek, Inga-Malin, Alongi, Filippo, Clementel, Enrico, Fortpied, Catherine, Machingura, Abigirl, Boakye Oppong, Felix, Guckenberger, Matthias, and Ost, Piet

Published
2024
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16. Radiotherapy Use in Muscle-Invasive Bladder Cancer: Review of the Guidelines and Impact of Increased Awareness in Patient Referral at a Tertiary Center in Belgium

Author

Verghote F, Van Praet C, De Maeseneer D, Berquin C, Vanneste B, De Visschere P, Verbeke SL, and Fonteyne V

Subjects
urothelial carcinoma, patterns of care, patient preference, radiation, underutilization, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Flor Verghote,1,2 Charles Van Praet,2,3 Daan De Maeseneer,4 Camille Berquin,2,3 Ben Vanneste,1,2 Pieter De Visschere,5 Sofie LJ Verbeke,6 Valérie Fonteyne1,2 1Department of Radiation Oncology, Ghent University Hospital, Ghent, Belgium; 2Department of Human Structure and Repair, Ghent University, Ghent, Belgium; 3Department of Urology, Ghent University Hospital, Ghent, Belgium; 4Department of Medical Oncology, Ghent University Hospital, Ghent, Belgium; 5Department of Radiology and Nuclear Medicine, Ghent University Hospital, Ghent, Belgium; 6Department of Pathology, Ghent University Hospital, Ghent, BelgiumCorrespondence: Flor Verghote, Department of Radiation Oncology, Ghent University Hospital, Corneel Heymanslaan 10, Ghent, 9000, Belgium, Tel +329332.30.15, Fax +323323015, Email flor.verghote@uzgent.bePurpose: Pronounced underuse of radiotherapy (RT) in muscle-invasive bladder cancer (MIBC) is reported. This study aims to assess the awareness about the role of RT in different MIBC settings and see whether this has increased since 2017.Materials and Methods: We reviewed the bladder cancer guidelines of the EAU, ESMO, NCCN, NICE, and AUA/ASCO/ASTRO/SUO, focusing on the role of RT in MIBC. In 2017, we evaluated the use of RT in MIBC in Belgium. This raised awareness about the indications of RT in different MIBC settings. Here, we present a retrospective pattern of care analysis of the RT use for MIBC patients at our center from January 2012 until December 2021. Frequency of RT use, patient, disease and treatment characteristics were compared between two 5-year periods (2012– 2016 and 2017– 2021).Results: Review of the guidelines suggested that RT can be used as a treatment option in most MIBC settings. However, differences between guideline recommendations existed and high-level evidence was often lacking. Overall, 221 unique MIBC patients received RT at our center. RT use for MIBC was 39% higher in the second 5-year period (Between the same periods, the number of new MIBC registrations increased with 26%). The most pronounced increase, ie, 529%, was observed in the primary setting and was in parallel with patient preference becoming the main indication for RT. Participation in clinical trials seems to have had an important impact on the frequency of RT use in the adjuvant and metastatic setting.Conclusion: We provide a critical overview of the RT indications in MIBC as recommended by the international guidelines. Increased awareness about RT as a treatment option in MIBC seems to have an impact on the treatment choice in clinical practice, as was observed in our tertiary center.Keywords: urothelial carcinoma, patterns of care, patient preference, radiation, underutilization

Published
2023

19. Topical fosaprepitant for the treatment of ocular pain and inflammation

Author

Giuseppe Suanno, Matteo Pederzolli, Romina Mayra Lasagni Vitar, Philippe Fonteyne, and Giulio Ferrari

Subjects
Ocular pain, Corneal inflammation, Substance P, Fosaprepitant, Ophthalmology, RE1-994
Abstract

Purpose: To assess whether topical administration of fosaprepitant improves intractable chronic ocular pain and inflammation. Methods: We report three clinical cases of female patients with drug-resistant ocular pain associated with inflammatory diseases of the ocular surface. The patients were treated for 3 (case 1) and 4 (cases 2–3) weeks with fosaprepitant eyedrops (0.1 mg/mL for case 1; 10 mg/mL for case 2–3). Patients were then followed up for at least 3 weeks. We measured ocular pain with the Visual Analogue Scale (VAS), the Ocular Surface Disease Index (OSDI), and corneal sensitivity with the Cochet-Bonnet esthesiometry. Slit-lamp photography and corneal confocal imaging were used to assess ocular surface integrity/conjunctival hyperemia and corneal nerve morphology, respectively. Results: All three patients had severe ocular pain (score higher than 6/10 VAS scale). All patients reported a significant improvement in ocular pain after 1 week of treatment. We also observed reduced corneal epitheliopathy (case 1) and conjunctival hyperemia (cases 1–2). In two patients (cases 2–3) the treatment was repeated after 1 year and 9 weeks, respectively, and pain reduction was similar in magnitude to what we observed after the first administration. Conclusions: Topical administration of fosaprepitant ameliorates ocular pain and clinical symptoms in three patients with intractable ocular pain associated with inflammatory diseases of the ocular surface, without adverse effects. Importance: Fosaprepitant instillation holds promise as a treatment of chronic ocular pain, an area of unmet medical need.

Published
2023
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21. Definition and Diagnosis of Oligometastatic Bladder Cancer: A Delphi Consensus Study Endorsed by the European Association of Urology, European Society for Radiotherapy and Oncology, and European Society of Medical Oncology Genitourinary Faculty

Author

Bamias, Aristotelis, Stenzl, Arnulf, Brown, Stephanie L., Albiges, Laurence, Babjuk, Marko, Birtle, Alison, Briganti, Alberto, Burger, Maximilian, Choudhury, Ananya, Colecchia, Maurizio, De Santis, Maria, Fanti, Stefano, Fonteyne, Valérie, Gallucci, Michele, Rivas, Juan Gómez, Huddart, Robert, Junker, Kerstin, Kroeze, Stephanie, Loriot, Yohann, Merseburger, Axel, Montironi, Rodolfo, Necchi, Andrea, Oing, Christoph, Oldenburg, Jan, Ost, Piet, Pinkawa, Michael, Ribal, Maria J., Rouprêt, Morgan, Thoeny, Harriet, Zilli, Thomas, and Hoskin, Peter

Published
2023
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22. Is It Safe to Switch from a Standard Anterior to Retzius-Sparing Approach in Robot-Assisted Radical Prostatectomy?

Author

Edward Lambert, Charlotte Allaeys, Camille Berquin, Pieter De Visschere, Sofie Verbeke, Ben Vanneste, Valerie Fonteyne, Charles Van Praet, and Nicolaas Lumen

Subjects
radical prostatectomy, Retzius-sparing, urinary continence, erectile dysfunction, biochemical recurrence, robotic surgery, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Background: Retzius-sparing robot-assisted radical prostatectomy (RS-RARP) has been shown to lead to better outcomes regarding early continence compared to standard anterior RARP (SA-RARP). The goal of this study was to assess the feasibility and safety of implementing RS-RARP in a tertiary center with experience in SA-RARP. Methods: From February 2020, all newly diagnosed non-metastatic prostate cancer patients for whom RARP was indicated were evaluated for RS-RARP. Data from the first 100 RS-RARP patients were prospectively collected and compared with data from the last 100 SA-RARP patients. Patients were evaluated for Clavien Dindo grade ≥3a complications, urinary continence after 2 and 6 weeks, 3, 6 and 12 months, erectile function, positive surgical margins (PSMs) and biochemical recurrence (BCR). Results: There was no significant difference in postoperative complications at Clavien-Dindo grade ≥3a (SA-RARP: 6, RS-RARP: 4; p = 0.292). At all time points, significantly higher proportions of RS-RARP patients were continent (p < 0.001). No significant differences in postoperative potency were observed (52% vs. 59%, respectively, p = 0.608). PSMs were more frequent in the RS-RARP group (43% vs. 29%, p = 0.034), especially in locally advanced tumors (pT3: 64.6% vs. 43.8%, p = 0.041—pT2: 23.5% vs. 15.4%, p = 0.329). The one-year BCR-free survival was 82.6% vs. 81.6% in the SA-RARP and RS-RARP groups, respectively (p = 0.567). The median follow-up was 22 [18–27] vs. 24.5 [17–35] months in the RS-RARP and SA-RARP groups, respectively (p = 0.008). Conclusions: The transition from SA-RARP to RS-RARP can be safely performed by surgeons proficient in SA-RARP. Continence results after RS-RARP were significantly better at any time point. A higher proportion of PSMs was observed, although it did not result in a worse BCR-free survival.

Published
2023
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25. Transcriptomic and clinical heterogeneity of metastatic disease timing within metastatic castration-sensitive prostate cancer

Author

Sutera, P.A., Shetty, A.C., Hakansson, A., Van der Eecken, K., Song, Y., Liu, Y., Chang, J., Fonteyne, V., Mendes, A.A., Lumen, N., Delrue, L., Verbeke, S., De Man, K., Rana, Z., Hodges, T., Hamid, A., Roberts, N., Song, D.Y., Pienta, K., Ross, A.E., Feng, F., Joniau, S., Spratt, D., Gillessen, S., Attard, G., James, N.D., Lotan, T., Davicioni, E., Sweeney, C., Tran, P.T., Deek, M.P., and Ost, P.

Published
2023
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28. Management of patients with advanced prostate cancer—metastatic and/or castration-resistant prostate cancer: Report of the Advanced Prostate Cancer Consensus Conference (APCCC) 2022

Author

Gillessen, Silke, Bossi, Alberto, Davis, Ian D., de Bono, Johann, Fizazi, Karim, James, Nicholas D., Mottet, Nicolas, Shore, Neal, Small, Eric, Smith, Matthew, Sweeney, Christopher J., Tombal, Bertrand, Antonarakis, Emmanuel S., Aparicio, Ana M., Armstrong, Andrew J., Attard, Gerhardt, Beer, Tomasz M., Beltran, Himisha, Bjartell, Anders, Blanchard, Pierre, Briganti, Alberto, Bristow, Rob G., Bulbul, Muhammad, Caffo, Orazio, Castellano, Daniel, Castro, Elena, Cheng, Heather H., Chi, Kim N., Chowdhury, Simon, Clarke, Caroline S., Clarke, Noel, Daugaard, Gedske, De Santis, Maria, Duran, Ignacio, Eeles, Ross, Efstathiou, Eleni, Efstathiou, Jason, Ekeke, Onyeanunam Ngozi, Evans, Christopher P., Fanti, Stefano, Feng, Felix Y., Fonteyne, Valerie, Fossati, Nicola, Frydenberg, Mark, George, Dan, Gleave, Martin, Gravis, Gwenaelle, Halabi, Susan, Heinrich, Daniel, Herrmann, Ken, Higano, Celestia, Hofman, Michael S., Horvath, Lisa G., Hussain, Maha, Jereczek-Fossa, Barbara A., Jones, Rob, Kanesvaran, Ravindran, Kellokumpu-Lehtinen, Pirkko-Liisa, Khauli, Raja B., Klotz, Laurence, Kramer, Gero, Leibowitz, Raja, Logothetis, Christopher, Mahal, Brandon, Maluf, Fernando, Mateo, Joaquin, Matheson, David, Mehra, Niven, Merseburger, Axel, Morgans, Alicia K., Morris, Michael J., Mrabti, Hind, Mukherji, Deborah, Murphy, Declan G., Murthy, Vedang, Nguyen, Paul L., Oh, William K., Ost, Piet, O’Sullivan, Joe M., Padhani, Anwar R., Pezaro, Carmel J., Poon, Darren M.C., Pritchard, Colin C., Rabah, Danny M., Rathkopf, Dana, Reiter, Robert E., Rubin, Mark A., Ryan, Charles J., Saad, Fred, Sade, Juan Pablo, Sartor, Oliver, Scher, Howard I., Sharifi, Nima, Skoneczna, Iwona, Soule, Howard, Spratt, Daniel E., Srinivas, Sandy, Sternberg, Cora N., Steuber, Thomas, Suzuki, Hiroyoshi, Sydes, Matthew R., Taplin, Mary-Ellen, Tilki, Derya, Türkeri, Levent, Turco, Fabio, Uemura, Hiroji, Uemura, Hirotsugu, Ürün, Yüksel, Vale, Claire L., van Oort, Inge, Vapiwala, Neha, Walz, Jochen, Yamoah, Kosj, Ye, Dingwei, Yu, Evan Y., Zapatero, Almudena, Zilli, Thomas, and Omlin, Aurelius

Published
2023
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30. Management of Patients with Advanced Prostate Cancer. Part I: Intermediate-/High-risk and Locally Advanced Disease, Biochemical Relapse, and Side Effects of Hormonal Treatment: Report of the Advanced Prostate Cancer Consensus Conference 2022

Author

Gillessen, Silke, Bossi, Alberto, Davis, Ian D., de Bono, Johann, Fizazi, Karim, James, Nicholas D., Mottet, Nicolas, Shore, Neal, Small, Eric, Smith, Matthew, Sweeney, Christopher, Tombal, Bertrand, Antonarakis, Emmanuel S., Aparicio, Ana M., Armstrong, Andrew J., Attard, Gerhardt, Beer, Tomasz M., Beltran, Himisha, Bjartell, Anders, Blanchard, Pierre, Briganti, Alberto, Bristow, Rob G., Bulbul, Muhammad, Caffo, Orazio, Castellano, Daniel, Castro, Elena, Cheng, Heather H., Chi, Kim N., Chowdhury, Simon, Clarke, Caroline S., Clarke, Noel, Daugaard, Gedske, De Santis, Maria, Duran, Ignacio, Eeles, Ros, Efstathiou, Eleni, Efstathiou, Jason, Ngozi Ekeke, Onyeanunam, Evans, Christopher P., Fanti, Stefano, Feng, Felix Y., Fonteyne, Valerie, Fossati, Nicola, Frydenberg, Mark, George, Daniel, Gleave, Martin, Gravis, Gwenaelle, Halabi, Susan, Heinrich, Daniel, Herrmann, Ken, Higano, Celestia, Hofman, Michael S., Horvath, Lisa G., Hussain, Maha, Jereczek-Fossa, Barbara Alicja, Jones, Robert, Kanesvaran, Ravindran, Kellokumpu-Lehtinen, Pirkko-Liisa, Khauli, Raja B., Klotz, Laurence, Kramer, Gero, Leibowitz, Raya, Logothetis, Christopher J., Mahal, Brandon A., Maluf, Fernando, Mateo, Joaquin, Matheson, David, Mehra, Niven, Merseburger, Axel, Morgans, Alicia K., Morris, Michael J., Mrabti, Hind, Mukherji, Deborah, Murphy, Declan G., Murthy, Vedang, Nguyen, Paul L., Oh, William K., Ost, Piet, O'Sullivan, Joe M., Padhani, Anwar R., Pezaro, Carmel, Poon, Darren M.C., Pritchard, Colin C., Rabah, Danny M., Rathkopf, Dana, Reiter, Robert E., Rubin, Mark. A., Ryan, Charles J., Saad, Fred, Pablo Sade, Juan, Sartor, Oliver A., Scher, Howard I., Sharifi, Nima, Skoneczna, Iwona, Soule, Howard, Spratt, Daniel E., Srinivas, Sandy, Sternberg, Cora N., Steuber, Thomas, Suzuki, Hiroyoshi, Sydes, Matthew R., Taplin, Mary-Ellen, Tilki, Derya, Türkeri, Levent, Turco, Fabio, Uemura, Hiroji, Uemura, Hirotsugu, Ürün, Yüksel, Vale, Claire L., van Oort, Inge, Vapiwala, Neha, Walz, Jochen, Yamoah, Kosj, Ye, Dingwei, Yu, Evan Y., Zapatero, Almudena, Zilli, Thomas, and Omlin, Aurelius

Published
2023
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32. Comparing symptom reporting by prostate cancer patients and healthcare professionals in the international multicentre REQUITE study

Author

Heumann, Philipp, Aguado-Barrera, Miguel E., Avuzzi, Barbara, Azria, David, Briers, Erik, Bultijnck, Renée, Choudhury, Ananya, De Ruysscher, Dirk, Farcy-Jacquet, Marie-Pierre, Fonteyne, Valérie, Gómez Caamaño, Antonio, Helmbold, Irmgard, Johnson, Kerstie, Kerns, Sarah L., Lambrecht, Maarten, Lingard, Zoe, Rancati, Tiziana, Rosenstein, Barry S., Sperk, Elena, Paul Symonds, R., Talbot, Christopher, Valdagni, Riccardo, Vega, Ana, Veldeman, Liv, Ward, Tim, Webb, Adam, West, Catharine M., Chang-Claude, Jenny, and Seibold, Petra

Published
2023
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36. Evaluation of aggregate stability methods for soil health

Author

Rieke, Elizabeth L., Bagnall, Dianna K., Morgan, Cristine L.S., Flynn, Kade D., Howe, Julie A., Greub, Kelsey L.H., Mac Bean, G., Cappellazzi, Shannon B., Cope, Michael, Liptzin, Daniel, Norris, Charlotte E., Tracy, Paul W., Aberle, Ezra, Ashworth, Amanda, Bañuelos Tavarez, Oscar, Bary, Andy I., Baumhardt, R.L., Borbón Gracia, Alberto, Brainard, Daniel C., Brennan, Jameson R., Briones Reyes, Dolores, Bruhjell, Darren, Carlyle, Cameron N., Crawford, James J.W., Creech, Cody F., Culman, Steve W., Deen, Bill, Dell, Curtis J., Derner, Justin D., Ducey, Thomas F., Duiker, Sjoerd W., Dyck, Miles F., Ellert, Benjamin H., Entz, Martin H., Espinosa Solorio, Avelino, Fonte, Steven J., Fonteyne, Simon, Fortuna, Ann-Marie, Foster, Jamie L., Fultz, Lisa M., Gamble, Audrey V., Geddes, Charles M., Griffin-LaHue, Deirdre, Grove, John H., Hamilton, Stephen K., Hao, Xiying, Hayden, Zachary D., Honsdorf, Nora, Ippolito, James A., Johnson, Gregg A., Kautz, Mark A., Kitchen, Newell R., Kumar, Sandeep, Kurtz, Kirsten S.M., Larney, Francis J., Lewis, Katie L., Liebman, Matt, Lopez Ramirez, Antonio, Machado, Stephen, Maharjan, Bijesh, Martinez Gamiño, Miguel Angel, May, William E., McClaran, Mitchel P., McDaniel, Marshall D., Millar, Neville, Mitchell, Jeffrey P., Moore, Amber D., Moore, Philip A., Jr., Mora Gutiérrez, Manuel, Nelson, Kelly A., Omondi, Emmanuel C., Osborne, Shannon L., Osorio Alcalá, Leodegario, Owens, Phillip, Pena-Yewtukhiw, Eugenia M., Poffenbarger, Hanna J., Ponce Lira, Brenda, Reeve, Jennifer R., Reinbott, Timothy M., Reiter, Mark S., Ritchey, Edwin L., Roozeboom, Kraig L., Rui, Yichao, Sadeghpour, Amir, Sainju, Upendra M., Sanford, Gregg R., Schillinger, William F., Schindelbeck, Robert R., Schipanski, Meagan E., Schlegel, Alan J., Scow, Kate M., Sherrod, Lucretia A., Shober, Amy L, Sidhu, Sudeep S., Solís Moya, Ernesto, St. Luce, Mervin, Strock, Jeffrey S., Suyker, Andrew E., Sykes, Virginia R., Tao, Haiying, Trujillo Campos, Alberto, Van Eerd, Laura L., van Es, Harold M., Verhulst, Nele, Vyn, Tony J., Wang, Yutao, Watts, Dexter B., Wright, David L., Zhang, Tiequan, and Honeycutt, C. Wayne

Published
2022
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39. Réflexions interdisciplinaires pour l’accompagnement de demandes d’euthanasie de mineurs en Belgique

Author

Franck Devaux, Claire Van Pevenage, and Christine Fonteyne

Subjects
pediatrics, euthanasia, interdisciplinarity, palliative care, Belgium, ethics, Ethnology. Social and cultural anthropology, GN301-674, The family. Marriage. Woman, HQ1-2044
Abstract

Research framework: In Belgium, euthanasia was made available to minors in February 2014. The request to die must be expressed by the minor and receive parental consent. It is regulated by an interdisciplinary process and support for situations of constant, unbearable and unappeasable physical suffering presenting no other reasonable solution in the context of an incurable condition. Objectives: Share reflections and recommendations on support for children, their families and teams in the context of euthanasia requests. They aim to point out the elements that this support has in common with any care process, but also those that characterize it specifically. Methodology: Since 2014, the pediatric palliative care mobile team of the Queen Fabiola University Children's Hospital (HUDERF) of the Brussels University Hospital (HUB) of the Université Libre de Bruxelles (ULB) has met regularly on an interdisciplinary basis to examine and discuss the various aspects of the law. Results: The outcome of this dialogue opens up a field of reflection and guidelines for ensuring appropriate, regulated care. Its aim is to support all those involved in the emergence of a request for euthanasia. The aim is not to define a strict framework, but to propose generalizable benchmarks capable of ensuring dynamic, non-linear, collaborative and comprehensive care. Conclusions: Euthanasia is a process of care and accompaniment that follows the multiple rhythms of the people for whom it is responsible. A human and interdisciplinary constellation is needed to guide this process. Contribution: Euthanasia of minors in Belgium is a rare practice, little studied but never trivial. This article examines the exceptional singularity of this care process and the interdisciplinary resources needed to support it.

Published
2023

41. An evaluation of carbon indicators of soil health in long-term agricultural experiments

Author

Liptzin, Daniel, Norris, Charlotte E., Cappellazzi, Shannon B., Bean, G. Mac, Cope, Michael, Greub, Kelsey L.H., Rieke, Elizabeth L., Tracy, Paul W., Aberle, Ezra, Ashworth, Amanda, Bañuelos Tavarez, Oscar, Bary, Andy I., Baumhardt, R.L., Borbón Gracia, Alberto, Brainard, Daniel C., Brennan, Jameson R., Briones Reyes, Dolores, Bruhjell, Darren, Carlyle, Cameron N., Crawford, James J.W., Creech, Cody F., Culman, Steve W., Deen, Bill, Dell, Curtis J., Derner, Justin D., Ducey, Thomas F., Duiker, Sjoerd W., Dyck, Miles F., Ellert, Benjamin H., Entz, Martin H., Espinosa Solorio, Avelino, Fonte, Steven J., Fonteyne, Simon, Fortuna, Ann-Marie, Foster, Jamie L., Fultz, Lisa M., Gamble, Audrey V., Geddes, Charles M., Griffin-LaHue, Deirdre, Grove, John H., Hamilton, Stephen K., Hao, Xiying, Hayden, Zachary D., Honsdorf, Nora, Howe, Julie A., Ippolito, James A., Johnson, Gregg A., Kautz, Mark A., Kitchen, Newell R., Kumar, Sandeep, Kurtz, Kirsten S.M., Larney, Francis J., Lewis, Katie L., Liebman, Matt, Lopez Ramirez, Antonio, Machado, Stephen, Maharjan, Bijesh, Martinez Gamiño, Miguel Angel, May, William E., McClaran, Mitchel P., McDaniel, Marshall D., Millar, Neville, Mitchell, Jeffrey P., Moore, Amber D., Moore, Philip A., Jr., Mora Gutiérrez, Manuel, Nelson, Kelly A., Omondi, Emmanuel C., Osborne, Shannon L., Osorio Alcalá, Leodegario, Owens, Philip, Pena-Yewtukhiw, Eugenia M., Poffenbarger, Hanna J., Ponce Lira, Brenda, Reeve, Jennifer R., Reinbott, Timothy M., Reiter, Mark S., Ritchey, Edwin L., Roozeboom, Kraig L., Rui, Yichao, Sadeghpour, Amir, Sainju, Upendra M., Sanford, Gregg R., Schillinger, William F., Schindelbeck, Robert R., Schipanski, Meagan E., Schlegel, Alan J., Scow, Kate M., Sherrod, Lucretia A., Shober, Amy L., Sidhu, Sudeep S., Solís Moya, Ernesto, St Luce, Mervin, Strock, Jeffrey S., Suyker, Andrew E., Sykes, Virginia R., Tao, Haiying, Trujillo Campos, Alberto, Van Eerd, Laura L., van Es, Harold, Verhulst, Nele, Vyn, Tony J., Wang, Yutao, Watts, Dexter B., Wright, David L., Zhang, Tiequan, Morgan, Cristine L.S., and Honeycutt, C. Wayne

Published
2022
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43. Pig models for Duchenne muscular dystrophy – from disease mechanisms to validation of new diagnostic and therapeutic concepts

Author

Stirm, Michael, Fonteyne, Lina Marie, Shashikadze, Bachuki, Stöckl, Jan B., Kurome, Mayuko, Keßler, Barbara, Zakhartchenko, Valeri, Kemter, Elisabeth, Blum, Helmut, Arnold, Georg J., Matiasek, Kaspar, Wanke, Rüdiger, Wurst, Wolfgang, Nagashima, Hiroshi, Knieling, Ferdinand, Walter, Maggie C., Kupatt, Christian, Fröhlich, Thomas, Klymiuk, Nikolai, Blutke, Andreas, and Wolf, Eckhard

Published
2022
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44. Linking soil microbial community structure to potential carbon mineralization: A continental scale assessment of reduced tillage

Author

Rieke, Elizabeth L., Cappellazzi, Shannon B., Cope, Michael, Liptzin, Daniel, Mac Bean, G., Greub, Kelsey L.H., Norris, Charlotte E., Tracy, Paul W., Aberle, Ezra, Ashworth, Amanda, Bañuelos Tavarez, Oscar, Bary, Andy I., Baumhardt, R.L., Borbón Gracia, Alberto, Brainard, Daniel C., Brennan, Jameson R., Briones Reyes, Dolores, Bruhjell, Darren, Carlyle, Cameron N., Crawford, James J.W., Creech, Cody F., Culman, Steve W., Deen, Bill, Dell, Curtis J., Derner, Justin D., Ducey, Thomas F., Duiker, Sjoerd W., Dyck, Miles F., Ellert, Benjamin H., Espinosa Solorio, Avelino, Fonte, Steven J., Fonteyne, Simon, Fortuna, Ann-Marie, Foster, Jamie L., Fultz, Lisa M., Gamble, Audrey V., Geddes, Charles M., Griffin-LaHue, Deirdre, Grove, John H., Hamilton, Stephen K., Hao, Xiying, Hayden, Zachary D., Honsdorf, Nora, Howe, Julie A., Ippolito, James A., Johnson, Gregg A., Kautz, Mark A., Kitchen, Newell R., Kumar, Sandeep, Kurtz, Kirsten S.M., Larney, Francis J., Lewis, Katie L., Liebman, Matt, Lopez Ramirez, Antonio, Machado, Stephen, Maharjan, Bijesh, Martinez Gamiño, Miguel Angel, May, William E., McClaran, Mitchel P., McDaniel, Marshall D., Millar, Neville, Mitchell, Jeffrey P., Moore, Amber D., Moore, Philip A., Jr., Mora Gutiérrez, Manuel, Nelson, Kelly A., Omondi, Emmanuel C., Osborne, Shannon L., Osorio Alcalá, Leodegario, Owens, Philip, Pena-Yewtukhiw, Eugenia M., Poffenbarger, Hanna J., Ponce Lira, Brenda, Reeve, Jennifer R., Reinbott, Timothy M., Reiter, Mark S., Ritchey, Edwin L., Roozeboom, Kraig L., Rui, Yichao, Sadeghpour, Amir, Sainju, Upendra M., Sanford, Gregg R., Schillinger, William F., Schindelbeck, Robert R., Schipanski, Meagan E., Schlegel, Alan J., Scow, Kate M., Sherrod, Lucretia A., Shober, Amy L., Sidhu, Sudeep S., Solís Moya, Ernesto, St Luce, Mervin, Strock, Jeffrey S., Suyker, Andrew E., Sykes, Virginia R., Tao, Haiying, Trujillo Campos, Alberto, Van Eerd, Laura L., Verhulst, Nele, Vyn, Tony J., Wang, Yutao, Watts, Dexter B., William, Bryan B., Wright, David L., Zhang, Tiequan, Morgan, Cristine L.S., and Honeycutt, C. Wayne

Published
2022
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45. Does Studying Latin in Secondary Education Predict Study Achievement in Academic Higher Education?

Author

Hauspie, Cathy, Schelfhout, Stijn, Dirix, Nicolas, Fonteyne, Lot, Janse, Mark, Szmalec, Arnaud, Vereeck, Alexandra, and Duyck, Wouter

Subjects
SECONDARY education, CLASSICAL languages, LATIN language, HIGHER education, LINGUISTICS
Abstract

Studying Latin in secondary education is still widespread in Europe and believed to result in cognitive benefits, even beyond the linguistic domain. In this study we explored the relation between such study and later academic achievement in higher education (N = 1,898). First, we demonstrated that Latin students exhibit increased levels of study achievement in higher education, particularly in study programs other than those covering science, technology, engineering, and mathematics (STEM). Second, we explored where the instruction of Latin was a significant predictor in models of academic achievement, explaining incremental variance over 21 other cognitive, attitudinal, and demographic variables. Latin instruction was included as a variable in the prediction models in 42% of the programs (mainly in the non‐STEM ones), but the incremental predictive validity was substantial only in the linguistic programs. Our results highlight how the study of Latin can be a valuable predictor of academic achievement in other study fields. A one‐page Accessible Summary of this article in nontechnical language is freely available in the Supporting Information online and at https://oasis‐database.org [ABSTRACT FROM AUTHOR]

Published
2024
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46. From Interest Assessment to Study Orientation: An Empirical Advice Set Engine

Author

Schelfhout, Stijn, Wille, Bart, Fonteyne, Lot, Roels, Elisabeth, De Fruyt, Filip, and Duyck, Wouter

Abstract

Each student faces the challenge of choosing a study program that matches his or her vocational interest. A good person-environment fit (PE fit) between student and study program influences study success and persistence, prerequisites to obtaining the desired degree. But which criterion should be used when presenting advice sets of study options to orient students toward study programs that match their vocational interests? And how long should such a list of study options be? Moving beyond existing, non-evidence-based approaches, the present study sets out to develop an empirical advice set engine (EASE) to optimize the process of matching future students to fitting study options. Compared to existing, non-evidence-based alternatives, EASE shows a better balance between the number and PE fit of the options presented. EASE may be a promising way to rethink how student PE fit information can be used in student orientation and higher education research.

Published
2021
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48. Use of angiotensin converting enzyme inhibitors is associated with reduced risk of late bladder toxicity following radiotherapy for prostate cancer

Author

Azria, David, Briers, Erik, Chang-Claude, Jenny, Choudhury, Ananya, Dunning, Alison, Elliott, Rebecca M, Gutiérrez-Enríquez, Sara, Rancati, Tiziana, Rattay, Tim, Rosenstein, Barry S., De Ruysscher, Dirk, Seibold, Petra, Sperk, Elena, Paul Symonds, R, Stobart, Hilary, Talbot, Christopher J., Vega, Ana, Veldeman, Liv, Ward, Tim, Webb, Adam, West, Catharine M., Kerns, Sarah L., Amidon Morlang, Ashley, Lee, Sharon M., Peterson, Derick R., Marples, Brian, Zhang, Hong, Bylund, Kevin, Rosenzweig, Doug, Hall, William, De Ruyck, Kim, Stock, Richard G., Gómez-Caamaño, Antonio, Sosa-Fajardo, Paloma, Taboada-Valladares, Begoña, Aguado-Barrera, Miguel E., Parker, Chris, Fonteyne, Valérie, Bultijnck, Renée, Symonds, R. Paul, Johnson, Kerstie, Lambrecht, Maarten, de Ruysscher, Dirk, Vanneste, Ben, Elliott, Rebecca M., Herskind, Carsten, Veldwijk, Marlon R., Avuzzi, Barbara, Valdagni, Riccardo, Farcy Jacquet, Marie-Pierre, West, Catharine, Janelsins, Michelle, Chen, Yuhchyau, Messing, Edward, and Morrow, Gary

Published
2022
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49. Dosimetric and Hematologic Implications of Prostate-Only Versus Whole Pelvic Radiotherapy: Results of the Multicentric Phase 3 PROPER Study

Author

Valérie Fonteyne MD, PhD, Willeke Danckaert Msc, Piet Ost MD, PhD, Charlien Berghen MD, PhD, Katrien Vandecasteele MD, PhD, Ben Vanneste MD, PhD, Kato Rans MD, Nick Liefhooghe MD, Steven Wallaert Msc, and Leen Paelinck PhD

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Objectives: The aim is to evaluate the incidental dose to the lymphatic regions in prostate-only radiotherapy (PORT) and to compare hematological outcome between PORT and whole pelvic radiotherapy (WPRT) in node-positive prostate cancer (pN1 PCa), in the era of modern radiotherapy techniques. Methods: We performed a prospective phase 3 trial in which a total of 64 pN1 PCa patients were randomized between PORT (ARM A) and WPRT (ARM B) delivered with volumetric-modulated arc therapy (VMAT). The lymph node (LN) regions were delineated separately and differences between groups were calculated using Welch t -tests. Hematological toxicity was scored according to common terminology criteria for adverse events (CTCAE) version 4.03. To evaluate differences in the evolution of red blood cell (RBC), white blood cell (WBC), and platelet count over time between PORT and WPRT, 3 linear mixed models with a random intercept for the patient was fit with model terms randomization group, study time point, and the interaction between both categorical predictors. Results: Except for dose to the obturator region, the incidental dose to the surrounding LN areas was low in ARM A. None of the patients developed severe hematological toxicity. The change in RBC from time point pre-external beam radiotherapy (EBRT) to month 3 and for WBC from time point pre-EBRT to months 3 and 12 was significantly different with ARM B showing a larger decrease. Conclusion: The incidental dose to the lymphatic areas becomes neglectable when PORT is delivered with VMAT. Hematological toxicity is very low after WPRT with VMAT and when bone marrow constraints are used for planning, although WPRT causes a decrease in RBC and WBC count over time.

Published
2023
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50. Case report: Subacute transverse myelitis with gait preservation secondary to Lyme disease and a review of the literature

Author

Charlotte Colot, Catherine Adler, Céline Mignon, Alessandro De Leucio, Patrice Jissendi, Jean Fonteyne, and Alec Aeby

Subjects
transverse myelitis (TM), Lyme disease (LD), subacute, gait preservation, review, Pediatrics, RJ1-570
Abstract

Subacute presentation with gait preservation is rare in the initial presentation of transverse myelitis (TM) in children. Lyme TM is poorly described in the literature. Here, we present the case of a 10-year-old boy who presented with neck pain with irradiation in the upper limbs for 13 days, accompanied by a right latero-torticollis. Magnetic resonance imaging (MRI) of the spine showed a hypersignal in the centromedullary T2 weighted image (WI) between C1 and C7, which was suggestive of cervical TM. A lumbar puncture revealed pleocytosis and proteinorachia. The test results of Borrelia IgG in the blood and intrathecal IgG synthesis were positive, confirming the diagnosis of TM secondary to Lyme disease. The patient was treated with high doses of steroids and antibiotics, following which he recovered completely. After a review of the clinical features of the eight previously published pediatric cases, we can conclude that Lyme TM usually has a subacute clinical presentation and is frequently limited to the cervical spine with pure sensory symptoms and gait preservation. Moreover, acute and chronic sphincter dysfunction is rare, and recovery is usually complete.

Published
2023
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