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of the poster presented at the NanoteC19 conference, International Conference on Carbon Nanosciene and Nanotechnology, 27th-30th August, Zaragoza (Spain).

Supercritical extraction of chia seed oil– experimental and modeling studies

The best choice for feeding the newborn child is breast milk, and when it is not possible to breastfeed a baby, the breast milk is replaced by lacteal formula, which is why numerous studies focus their attention on the analysis of the diverse components of baby formula as well as functions in the breastfed baby. Fatty acids are components of great nutritional importance in the fetus and in the newborn child. Nowadays it is estimated that the fetus, during the last trimester of the gestational period and the newborn child, during the first six months of life, need a great contribution of araquidonic and docosahexaenoic acids, due to the fact that the speed of transformation of the predecessors to the hepatic level are not sufficient to cover the metabolic requirements of these fatty acids and it is the mother who contributes them through placental transport during gestation and her milk during lactation. The Organization of Food and Agriculture (FAO), the World Health Organization (WHO), the European Society of Gastroenterology, Hepatology and Pediatric Nutrition (ESPGHAN) and the American Academy of Pediatrics recommend that lacteal formula imitate the composition of the breast milk, especially in the fatty polyunsaturated acids (PUFA). El alimento natural por excelencia para el recién nacido es la leche materna, cuando no es posible darla se sustituye por fórmulas lácteas, por lo que numerosos estudios enfocan su interés en el análisis de los diversos componentes de éstas, y sus funciones en el lactante. Los ácidos grasos son componentes de gran importancia nutricional tanto en el feto como en el recién nacido. Actualmente se estima que el feto, durante el último tercio del periodo gestacional y el recién nacido, durante los primeros seis meses de vida, requieren un gran aporte de ácidos araquidónico y docosahexaenoico, debido a que la velocidad de transformación de los precursores a nivel hepático no son suficientes para cubrir los requerimientos metabólicos de éstos ácidos grasos y es la madre quien los aporta a través del transporte placentario durante la gestación y a través de la leche durante la lactancia. La Organización para Alimentación y Agricultura (FAO), la Organización Mundial de la Salud (OMS) y la Sociedad Europea de Gastroenterología, Hepatología y Nutrición Pediátrica (ESPGHAN), así como la Academia Americana de Pediatría recomiendan que las fórmulas lácteas deben ser inocuas y similares a la composición de la leche humana y muy especialmente en los ácidos grasos poliinsaturados (PUFA).

3 figuras.-- Trabajo presentado en el Encuentro Anual IberNAM "Empresas de Base Tecnológica en Micro-Nanosistemas: experiencias y oportunidades de colaboración” Zaragoza, (España), 10-11 Diciembre 2015., Películas de óxido de grafeno depositadas por aerografiado, y de fibras de PVA/óxido de grafeno fabricadas por electrohilado se integraron en sensores SAW de ondas Love para a la detección de simulantes de armas químicas. Los sensores presentaron alta sensibilidad y respuestas reversibles y lineales con la concentración de analito. Valores de límite de detección de 9 and 40 ppb se han calculado para DMMP y DPGME, respectivamente. La respuesta de los sensores se explica por la formación de enlaces de hidrógeno entre los analitos y el óxido de grafeno en procesos de fisisorción., Este trabajo ha sido subvencionado por el Ministerio de Ciencia e Innovación (TEC2013-C6- 4-R) y por EPSRC. Los autores agradecen a C. Cané e I. Gràcia del Centro Nacional de Microelectrónica IMB-CSIC por proporcionar substratos SAW.

The aim of this study was to evaluate the effect of ß-cyclodextrin (ß-CD) on phospholipids and cholesterol in raw pasteurized milk with the purpuse on removal cholesterol from the milk fat. Total phospholipids decrease slightly in ß-CD treated milk but were not signinificantly affected by the effect of the ß-CD. ß-CD is an effective oligosacharide for cholesterol removal from milk with more than 97% of reduction and does not affect significantly the individual phospholipids (phosphatidylcholine, phosphatidylethanolamine, sphingomyelin, phosphatidylinositol and phosphatidylserina) of the milk fat globule membrane., The authors thanks to the Ministry of Economy and Competitiveness from Spain (grant number AGL-2011-26713).

Poster presented at the XXX Trobades Científiques de la Mediterrània, Josep Miquel Vidal, Graphene and related materials: production, characterization, applications. 15th - 17th october, 2014, Menorca (Spain)., Surface acoustic wave (SAW) sensors have high sensitivity, high stability and signal easy to process. In order to achieve high sensitivity in SAW sensors, it is essential to confine the maximum amount of acoustic energy near the surface of the substrate and minimize wave scattering into the bulk of the substrate. These devices are based on the excitation of shear horizontal surface acoustic waves (SH-SAW) in a piezoelectric substrate, guided by a layer deposited over it and can be used for gas/liquid detection. A key issue in their design is the choice of sensitive layer. Gaphene oxide (GO) is a very attractive nanomaterial for sensor applications because it combines 2D structural features of graphene and the presence of oxygen-containing functional groups (mainly, epoxide, hydroxyl and carbonyl groups), which can potentially interact with a great variety of analytes. Besides, GO can act as a substrate and to be interfaced with various biomolecules and cells, therefore these SH-SAW sensors could be also used to biological detection. In this work, we present the first results obtained with a GO SH-SAW sensor for the detection of (CWA) simulants .

2 figures.-- Poster presented at the 7as Jornadas Hispano‐Francesas, Meeting IBERNAM-CMC2. Microsystems & Nanotechnology. November 20th-21st, 2014, Naturgas Energía, Bilbao, Spain., Graphene oxide (GO) is a very attractive nanomaterial for sensor applications as it combines 2D structural features of graphene and the presence of oxygen-containing functional groups (mainly, epoxide, hydroxyl and carbonyl groups) (1,2) which can potentially interact with a great variety of analytes. Besides, GO offers promise for its use as substrate to be interfaced with biomolecules and cells for biological detection. Recent studies have focused on the applications of the GO in resistive sensors for the detection of pollutant gases (such as CO2, NH3, H2, NO), chemical warfare agent (CWAs) and explosives (3,4). However, to the best of our knowledge, GO has hardly been used in SAW or Love-wave sensors (5). We have developed a Love-wave SAW sensor with three-layer structure consists in ST-cut quartz as substrate, SiO2 as guiding layer and GO as sensitive layer. In this work, we present the first results obtained with GO Love-SAW sensor for the detection of CWA simulants. The sensor detected very low concentrations of dimethyl-methylphosphonate (DMMP) and dipropylene glycol monomethyl ether (DPGME), simulants of sarin nerve gas and nitrogen mustard, respectively., Authors want to thank Spanish Ministry of Economy and Competitiveness for supporting the project TEC2013-48147-C6-4-R

International audience; The goal has been to develop an immunosensor based on a Love-wave device and a PDMS microfluidic chip in order to detect potentially pathogenic microorganisms in real time. Therefore, it has been tested with the phage M13 detected through the mouse monoclonal antibody anti-M13 (AM13). The Double-layer Agar (DLA) technique has been used to quantify the number of phages, linked to the sensor surface, in plaques-forming unit (pfu); that has allowed us to compare the number of phages determined by DLA and the estimated by the frequency shift, and both were very similar. With the aim to obtain a short response time, the detection of the phage was carried out in dynamic mode. The range tested concentrations has varied between 2x10^10 pfu*ml^-1 and 5x10^8 pfu*ml^-1. A fast response and a good discrimination among concentrations have been achieved. Besides, the AM13 has been used as secondary antibody in order to measure lower concentrations, such as 5*10^7 pfu*ml^-1.

A gonio-spectrophotometer developed and built at CSIC for bidirectional scattering distribution function (BSDF) low-uncertainty measurements is described. The measurement equation and the uncertainty analysis are explained, and first results on the BSDF of ceramic colour standards are shown. © 2011 Sociedad Española de Óptica., Los autores agradecen al Plan Nacional de Física el apoyo para la realización de este trabajo mediante la subvención de referencia FIS2007‐ 66671‐C02‐01, al Dr. Armanda del IAI (CSIC) por las discusiones mantenidas sobre el diseño mecánico y el sistema de sujeción, y al Programa JAE del CSIC por la concesión de la ayuda de Investigador en Formación.

The aim of the present study was to evaluate the use of β-cyclodextrin (β-CD) with pasteurized whole milk in an industrial process after churning the cream for making low cholesterol butter with the purpose of manufacturing commercial reduced cholesterol butter. Fatty acids and chemical gross composition (total fat, lactose, protein and total solids) of the untreated and 0.6% β-cyclodextrin (β-CD) treated butter were determined. Gas chromatography of the individual methyl esters fatty acids (saturated, monounsaturated and polyunsaturated acids) showed no significant effect by the addition of β-CD. Cholesterol reduction of the commercial butter was 95.53 ± 2.81% with a residual content of β-CD of 0.04 ± 0.01%. The rest of β-CD remains in the whey during the churning of the cream and in the skim milk. This process provides a considerable reduction of cholesterol in butter without altering the fatty acid composition of the milk fat.