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Introduction: PET-CT provides information for staging, surveillance of recurrence, and monitoring of treatment response in solid tumors. However, PET-CT is not routinely used in preoperative statiication or postoperative follow-up of patients with differentiated papillary thyroid cancer (DPTC). Objective: To describe the usefulness of the use of PET-CT in the diagnosis of CDT recurrence. Material and methods: All patients under CDT surveillance who presented negative imaging studies and had elevated serum thyroglobulin levels, or who had normal thyroglobulin levels and elevated Ac anti-Tg levels were selected. These patients underwent a PET-CT and were subsequently taken to surgery or biopsy to establish the clinical-pathological inding and its correlation with the PET-CT indings. Results: Locoregional neck recurrence was documented in 33 of 56 cases (58.9%). The average SUV-MAX value was 5.86 ± standard deviation 3.53. The histopathological diagnostic variable showed a statistically signiicant relationship with the SUV-MAX value with a t of -2.116 and a p of 0.04. A relationship of the variables with the PET-CT indings was estimated using the SUV-MAX value using the ANOVA statistical test. The age group variable showed a statistically signiicant relationship with SUV-MAX with an F value of 4.47 and a p of 0.03. Conclusions: PET-CT provides an important cabinet study in the diagnosis of CDT recurrence in patients with disease not measurable by other diagnostic means and with elevated serum thyroglobulin levels, or who had normal thyroglobulin levels and elevated Ac anti-Tg levels. [ABSTRACT FROM AUTHOR]

Introduction: Carcinomas with thyroglossal cyst localization have a low frequency, about 1% of patients present this disease; the most frequent histology is papillary thyroid carcinoma. We describe a case of papillary carcinoma of thyroglossal cyst. Clinical case: A 54-yearold man with an anterior cervical tumor of six months of evolution, not mobile, not painful, with diameters of 3 × 5 cm. Thyroid ultrasound with right thyroid nodule TIRADS 4c and suspicious adenopathies in level VI. Total thyroidectomy + Sistrunk was performed, with pathological report of multifocal conventional variant papillary carcinoma. It infiltrated thyroid capsule and adjacent prethyroid muscles; right lobe tumor 2 × 1.5 × 1.3 cm, left lobe tumor 3.5 × 3 × 4 cm; then, I-131 dose was applied. Discussion: There is no consensus regarding the ideal treatment of papillary carcinoma in the thyroglossal cyst, although Sistrunk surgery with total thyroidectomy seems to be the most appropriate one. As this is a rare presentation of well-differentiated thyroid cancer, it could be difficult to draw conclusions with a high level of evidence for its management, but they should be guided by current guidelines of well-differentiated thyroid cancer and decisions should be made in multidisciplinary teams. [ABSTRACT FROM AUTHOR]