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9. The GIN-McMaster guideline tool extension for the integration of quality improvement and quality assurance in guidelines: a description of the methods for its development.

Author

Piggott, T., Langendam, M.W., Parmelli, E., Adolfsson, J., Akl, E.A., Armstrong, D., Braithwaite, J., Brignardello-Petersen, R., Brozek, J., Follmann, M., Kopp, I., Meerpohl, J.J., Neamtiu, L., Nothacker, M., Qaseem, A., Rossi, P.G., Saz-Parkinson, Z., Wees, P.J. van der, Schünemann, H.J., Piggott, T., Langendam, M.W., Parmelli, E., Adolfsson, J., Akl, E.A., Armstrong, D., Braithwaite, J., Brignardello-Petersen, R., Brozek, J., Follmann, M., Kopp, I., Meerpohl, J.J., Neamtiu, L., Nothacker, M., Qaseem, A., Rossi, P.G., Saz-Parkinson, Z., Wees, P.J. van der, and Schünemann, H.J.

Abstract

01 februari 2023, Item does not contain fulltext, BACKGROUND AND OBJECTIVES: Our objective was to develop an extension of the widely used GIN-McMaster Guideline Development Checklist and Tool for the integration of quality assurance and improvement (QAI) schemes with guideline development. METHODS: We used a mixed-methods approach incorporating evidence from a systematic review, an expert workshop and a survey of experts to iteratively create an extension of the checklist for QAI through three rounds of feedback. As a part of this process, we also refined criteria of a good guideline-based quality indicator. RESULTS: We developed a 40-item checklist extension addressing steps for the integration of QAI into guideline development across the existing 18 topics and created one new topic specific to QAI. The steps span from 'organization, budget, planning and training', to updating of QAI and guideline implementation. CONCLUSION: The tool supports integration of QAI schemes with guideline development initiatives and it will be used in the forthcoming integrated European Commission Initiative on Colorectal Cancer. Future work should evaluate this extension and QAI items requiring additional support for guideline developers and links to QAI schemes.

Published
2023

15. Nutzung und Anwendbarkeit von Patientenleitlinien in der Onkologie aus Sicht der Leistungserbringenden – eine qualitative Interviewstudie

Author

Wahlen, S, Breuing, J, Becker, M, Bühn, S, Hauprich, J, Könsgen, N, Meyer, N, Bloedt, S, Carl, EG, Follmann, M, Frenz, S, Langer, T, Nothacker, M, Schaefer, C, and Pieper, D

Subjects
ddc: 610, Medicine and health
Abstract

Hintergrund und Stand (inter)nationaler Forschung: Menschen mit einer Krebserkrankung haben sowohl während als auch nach der Behandlung ein hohes Informationsbedürfnis, welches aber häufig nicht ausreichend erfüllt wird. Patientenleitlinien (PatLL), eine besondere Form der evidenzbasierten [zum vollständigen Text gelangen Sie über die oben angegebene URL]

Published
2022
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16. (Inter-)nationale Erfahrungen bei der Erstellung und Dissemination von PatientInnenleitlinien – eine Interviewstudie

Author

Hauprich, J, Breuing, J, Becker, M, Bühn, S, Könsgen, N, Meyer, N, Bloedt, S, Carl, EG, Follmann, M, Frenz, S, Langer, T, Nothacker, M, Schaefer, C, Wahlen, S, and Pieper, D

Subjects
ddc: 610, Medicine and health
Abstract

Hintergrund und Stand (inter)nationaler Forschung: Menschen mit einer Krebserkrankung weisen ein hohes Informationsbedürfnis auf, welches aktuell unzureichend erfüllt wird. Patientenleitlinien (PatLL) kommen diesem Bedürfnis nach, indem sie, basierend auf evidenzbasierten Leitlinien, [zum vollständigen Text gelangen Sie über die oben angegebene URL]

Published
2022
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18. Deutschsprachige Übersetzung des PANELVIEW-Instruments zur Evaluierung des Prozesses der Leitlinienentwicklung aus der Perspektive der Leitliniengruppe

Author

Gooßen, K, Becker, M, Mathes, T, Follmann, M, Holtkamp, U, Hostettler, S, Meerpohl, JJ, Nothacker, M, Schaefer, C, Schmidt, S, Schünemann, H, Sommer, I, Tholen, R, Skoetz, N, Pieper, D, Gooßen, K, Becker, M, Mathes, T, Follmann, M, Holtkamp, U, Hostettler, S, Meerpohl, JJ, Nothacker, M, Schaefer, C, Schmidt, S, Schünemann, H, Sommer, I, Tholen, R, Skoetz, N, and Pieper, D

Published
2022

21. Integrating Quality Assurance and Quality Improvement With Guidelines: Systematic Stakeholder-Driven Development of an Extension of the Guidelines International Network-McMaster Guideline Development Checklist

Author

Piggott, T., Langendam, M.W., Parmelli, E., Adolfsson, J., Akl, E.A., Armstrong, D., Braithwaite, J., Brignardello-Petersen, R., Brozek, J., Follmann, M., Kopp, I., Meerpohl, J.J., Neamtiu, L., Nothacker, M., Qaseem, A., Rossi, P.G., Saz-Parkinson, Z., Wees, P.J. van der, Schünemann, H.J., Piggott, T., Langendam, M.W., Parmelli, E., Adolfsson, J., Akl, E.A., Armstrong, D., Braithwaite, J., Brignardello-Petersen, R., Brozek, J., Follmann, M., Kopp, I., Meerpohl, J.J., Neamtiu, L., Nothacker, M., Qaseem, A., Rossi, P.G., Saz-Parkinson, Z., Wees, P.J. van der, and Schünemann, H.J.

Abstract

Item does not contain fulltext

Published
2022

22. S3 Guideline: Diagnosis and Therapy of Biliary Carcinoma Short Version 2.00-June 2021, AWMF Register Number: 032-053OL

Author

Bitzer, M., Voesch, S., Albert, J., Bartenstein, P., Bechstein, W., Bloedt, S., Brunner, T., Dombrowski, F., Evert, M., Follmann, M., La Fougere, C., Freudenberger, P., Geier, A., Gkika, E., Goetz, M., Hammes, E., Helmberger, T., Hoffmann, R. T., Hofmann, W. P., Huppert, P., Kautz, A., Knoetgen, G., Koerber, J., Krug, D., Lammert, F., Lang, H., Langer, T., Lenz, P., Mahnken, A., Meining, A., Micke, O., Nadalin, S., Nguyen, H. P., Ockenga, J., Oldhafer, K., Paprottka, P., Paradies, K., Pereira, P., Persigehl, T., Plauth, M., Plentz, R., Pohl, J., Riemer, J., Reimer, P., Ringwald, J., Ritterbusch, U., Roeb, E., Schellhaas, B., Schirmacher, P., Schmid, I, Schuler, A., von Schweinitz, D., Seehofer, D., Sinn, M., Stein, A., Stengel, A., Steubesand, N., Stoll, C., Tannapfel, A., Taubert, A., Trojan, J., van Thiel, I, Tholen, R., Vogel, A., Vogl, T., Vorwerk, H., Wacker, F., Waidmann, O., Wedemeyer, H., Wege, H., Wildner, D., Wittekind, C., Woerns, M. A., Galle, P., Malek, N., Bitzer, M., Voesch, S., Albert, J., Bartenstein, P., Bechstein, W., Bloedt, S., Brunner, T., Dombrowski, F., Evert, M., Follmann, M., La Fougere, C., Freudenberger, P., Geier, A., Gkika, E., Goetz, M., Hammes, E., Helmberger, T., Hoffmann, R. T., Hofmann, W. P., Huppert, P., Kautz, A., Knoetgen, G., Koerber, J., Krug, D., Lammert, F., Lang, H., Langer, T., Lenz, P., Mahnken, A., Meining, A., Micke, O., Nadalin, S., Nguyen, H. P., Ockenga, J., Oldhafer, K., Paprottka, P., Paradies, K., Pereira, P., Persigehl, T., Plauth, M., Plentz, R., Pohl, J., Riemer, J., Reimer, P., Ringwald, J., Ritterbusch, U., Roeb, E., Schellhaas, B., Schirmacher, P., Schmid, I, Schuler, A., von Schweinitz, D., Seehofer, D., Sinn, M., Stein, A., Stengel, A., Steubesand, N., Stoll, C., Tannapfel, A., Taubert, A., Trojan, J., van Thiel, I, Tholen, R., Vogel, A., Vogl, T., Vorwerk, H., Wacker, F., Waidmann, O., Wedemeyer, H., Wege, H., Wildner, D., Wittekind, C., Woerns, M. A., Galle, P., and Malek, N.

Published
2022

23. S3-Guideline - Diagnosis and Therapy of Biliary Carcinoma

Author

Bitzer, M., Voesch, S., Albert, J., Bartenstein, P., Bechstein, W., Bloedt, S., Brunner, T., Dombrowski, F., Evert, M., Follmann, M., La Fougere, C., Freudenberger, P., Geier, A., Gkika, E., Goetz, M., Hammes, E., Helmberger, T., Hoffmann, R. T., Hofmann, W. P., Huppert, P., Kautz, A., Knoetgen, G., Koerber, J., Krug, D., Lammert, F., Lang, H., Langer, T., Lenz, P., Mahnken, A., Meining, A., Micke, O., Nadalin, S., Nguyen, H. P., Ockenga, J., Oldhafer, K., Paprottka, P., Paradies, K., Pereira, P., Persigehl, T., Plauth, M., Plentz, R., Pohl, J., Riemer, J., Reimer, P., Ringwald, J., Ritterbusch, U., Roeb, E., Schellhaas, B., Schirmacher, P., Schmid, I, Schuler, A., von Schweinitz, D., Seehofer, D., Sinn, M., Stein, A., Stengel, A., Steubesand, N., Stoll, C., Tannapfel, A., Taubert, A., Trojan, J., van Thiel, I, Tholen, R., Vogel, A., Vogl, T., Vorwerk, H., Wacker, F., Waidmann, O., Wedemeyer, H., Wege, H., Wildner, D., Wittekind, C., Woerns, M. A., Galle, P., Malek, N., Bitzer, M., Voesch, S., Albert, J., Bartenstein, P., Bechstein, W., Bloedt, S., Brunner, T., Dombrowski, F., Evert, M., Follmann, M., La Fougere, C., Freudenberger, P., Geier, A., Gkika, E., Goetz, M., Hammes, E., Helmberger, T., Hoffmann, R. T., Hofmann, W. P., Huppert, P., Kautz, A., Knoetgen, G., Koerber, J., Krug, D., Lammert, F., Lang, H., Langer, T., Lenz, P., Mahnken, A., Meining, A., Micke, O., Nadalin, S., Nguyen, H. P., Ockenga, J., Oldhafer, K., Paprottka, P., Paradies, K., Pereira, P., Persigehl, T., Plauth, M., Plentz, R., Pohl, J., Riemer, J., Reimer, P., Ringwald, J., Ritterbusch, U., Roeb, E., Schellhaas, B., Schirmacher, P., Schmid, I, Schuler, A., von Schweinitz, D., Seehofer, D., Sinn, M., Stein, A., Stengel, A., Steubesand, N., Stoll, C., Tannapfel, A., Taubert, A., Trojan, J., van Thiel, I, Tholen, R., Vogel, A., Vogl, T., Vorwerk, H., Wacker, F., Waidmann, O., Wedemeyer, H., Wege, H., Wildner, D., Wittekind, C., Woerns, M. A., Galle, P., and Malek, N.

Published
2022

25. S3-Leitlinie – Diagnostik und Therapie biliärer Karzinome

Author

Bitzer, M., Voesch, S., Albert, J., Bartenstein, P., Bechstein, W., Blödt, S., Brunner, T., Dombrowski, F., Evert, M., Follmann, M., La Fougère, C., Freudenberger, P., Geier, A., Gkika, E., Götz, M., Hammes, E., Helmberger, T., Hoffmann, R.T., Hofmann, W.P., Huppert, P., Kautz, A., Knötgen, G., Körber, J., Krug, D., Lammert, F., Lang, H., Langer, T., Lenz, P., Mahnken, A., Meining, A., Micke, O., Nadalin, S., Nguyen, H.P., Ockenga, J., Oldhafer, K., Paprottka, P., Paradies, K., Pereira, P., Persigehl, T., Plauth, M., Plentz, R., Pohl, J., Riemer, J., Reimer, P., Ringwald, J., Ritterbusch, Ulrike, Roeb, E., Schellhaas, B., Schirmacher, P., Schmid, I., Schuler, A., von Schweinitz, D., Seehofer, D., Sinn, M., Stein, A., Stengel, A., Steubesand, N., Stoll, C., Tannapfel, A., Taubert, A., Trojan, J., van Thiel, I., Tholen, R., Vogel, A., Vogl, T., Vorwerk, H., Wacker, F., Waidmann, O., Wedemeyer, H., Wege, H., Wildner, D., Wittekind, C., Wörns, M.A., Galle, P., and Malek, N.

Subjects
Medizin
Published
2022

26. Benefits and harms of annual, biennial, or triennial breast cancer mammography screening for women at average risk of breast cancer: a systematic review for the European Commission Initiative on Breast Cancer (ECIBC)

Author

Canelo-Aybar, C, Posso, M, Montero, N, Sola, I, Saz-Parkinson, Z, Duffy, SW, Follmann, M, Grawingholt, A, Rossi, PG, and Alonso-Coello, P

Abstract

Background Although mammography screening is recommended in most European countries, the balance between the benefits and harms of different screening intervals is still a matter of debate. This review informed the European Commission Initiative on Breast Cancer (BC) recommendations. Methods We searched PubMed, EMBASE, and the Cochrane Library to identify RCTs, observational or modelling studies, comparing desirable (BC deaths averted, QALYs, BC stage, interval cancer) and undesirable (overdiagnosis, false positive related, radiation related) effects from annual, biennial, or triennial mammography screening in women of average risk for BC. We assessed the certainty of the evidence using the GRADE approach. Results We included one RCT, 13 observational, and 11 modelling studies. In women 50-69, annual compared to biennial screening may have small additional benefits but an important increase in false positive results; triennial compared to biennial screening may have smaller benefits while avoiding some harms. In younger women (aged 45-49), annual compared to biennial screening had a smaller gain in benefits and larger harms, showing a less favourable balance in this age group than in women 50-69. In women 70-74, there were fewer additional harms and similar benefits with shorter screening intervals. The overall certainty of the evidence for each of these comparisons was very low. Conclusions In women of average BC risk, screening intervals have different trade-offs for each age group. The balance probably favours biennial screening in women 50-69. In younger women, annual screening may have a less favourable balance, while in women aged 70-74 years longer screening intervals may be more favourable.

Published
2022

28. S3-Leitlinie – Diagnostik und Therapie biliärer Karzinome

Author

Bitzer, M., additional, Voesch, S., additional, Albert, J., additional, Bartenstein, P., additional, Bechstein, W., additional, Blödt, S., additional, Brunner, T., additional, Dombrowski, F., additional, Evert, M., additional, Follmann, M., additional, La Fougère, C., additional, Freudenberger, P., additional, Geier, A., additional, Gkika, E., additional, Götz, M., additional, Hammes, E., additional, Helmberger, T., additional, Hoffmann, R. T., additional, Hofmann, W. P., additional, Huppert, P., additional, Kautz, A., additional, Knötgen, G., additional, Körber, J., additional, Krug, D., additional, Lammert, F., additional, Lang, H., additional, Langer, T., additional, Lenz, P., additional, Mahnken, A., additional, Meining, A., additional, Micke, O., additional, Nadalin, S., additional, Nguyen, H. P., additional, Ockenga, J., additional, Oldhafer, K., additional, Paprottka, P., additional, Paradies, K., additional, Pereira, P., additional, Persigehl, T., additional, Plauth, M., additional, Plentz, R., additional, Pohl, J., additional, Riemer, J., additional, Reimer, P., additional, Ringwald, J., additional, Ritterbusch, U., additional, Roeb, E., additional, Schellhaas, B., additional, Schirmacher, P., additional, Schmid, I., additional, Schuler, A., additional, von Schweinitz, D., additional, Seehofer, D., additional, Sinn, M., additional, Stein, A., additional, Stengel, A., additional, Steubesand, N., additional, Stoll, C., additional, Tannapfel, A., additional, Taubert, A., additional, Trojan, J., additional, van Thiel, I., additional, Tholen, R., additional, Vogel, A., additional, Vogl, T., additional, Vorwerk, H., additional, Wacker, F., additional, Waidmann, O., additional, Wedemeyer, H., additional, Wege, H., additional, Wildner, D., additional, Wittekind, C., additional, Wörns, M. A., additional, Galle, P., additional, and Malek, N., additional

Published
2022
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33. Benefits and harms of breast cancer mammography screening for women at average risk of breast cancer: A systematic review for the European Commission Initiative on Breast Cancer

Author

Canelo-Aybar, C, Ferreira, DS, Ballesteros, M, Posso, M, Montero, N, Sola, I, Saz-Parkinson, Z, Lerda, D, Rossi, PG, Duffy, SW, Follmann, M, Grawingholt, A, and Alonso-Coello, P

Subjects
mass screening, breast cancer, mammography, Guidelines
Abstract

Objectives Mammography screening is generally accepted in women aged 50-69, but the balance between benefits and harms remains controversial in other age groups. This study systematically reviews these effects to inform the European Breast Cancer Guidelines. Methods We searched PubMed, EMBASE and Cochrane Library for randomised clinical trials (RCTs) or systematic reviews of observational studies in the absence of RCTs comparing invitation to mammography screening to no invitation in women at average breast cancer (BC) risk. We extracted data for mortality, BC stage, mastectomy rate, chemotherapy provision, overdiagnosis and false-positive-related adverse effects. We performed a pooled analysis of relative risks, applying an inverse-variance random-effects model for three age groups (

Published
2021

37. S2k-Leitlinie: Diagnostik und Management von Vorläuferläsionen des oralen Plattenepithelkarzinoms in der Zahn-, Mund- und Kieferheilkunde

Author

Kunkel, M., Bengel, W., Blume, M., Boehme, P., Buchholz, G.E., Follmann, M., Frank, M., Frerich, B., Kreusser, B., Löning, T., Mohr, P., Reichert, T.E., Remmerbach, T.W., Rumpf, M., Schmidt, J., Schütte, U., Singer, R., Stasche, N., Wagner, W., Wahl, G., Weber, A., Weingart, D., Wenz, H.-J., Werkmeister, R., and Hertrampf, K.

Published
2011
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39. German evidence-based guidelines for the treatment of Psoriasis vulgaris (short version)

Author

Nast, A., Kopp, I., Augustin, M., Banditt, K. B., Boehncke, W. H., Follmann, M., Friedrich, M., Huber, M., Kahl, C., Klaus, J., Koza, J., Kreiselmaier, I., Mohr, J., Mrowietz, U., Ockenfels, H. M., Orzechowski, H. D., Prinz, J., Reich, K., Rosenbach, T., Rosumeck, S., Schlaeger, M., Schmid-Ott, G., Sebastian, M., Streit, V., Weberschock, T., and Rzany, B.

Published
2007
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40. Guidelines 3.0: Digitalisierung von Leitlinien im Leitlinienprogramm Onkologie

Author

Langer, T, Wenzel, G, and Follmann, M

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund/Fragestellung: Im Rahmen des Leitlinienprogramms Onkologie werden seit 2008 die Erstellung und Aktualisierung von S3-Leitlinien gefördert. Das Programm umfasst mittlerweile 26 Leitlinien. Leitlinien werden in Deutschland bislang überwiegend als Word-Dokumente erstellt und [zum vollständigen Text gelangen Sie über die oben angegebene URL], Nützliche patientenrelevante Forschung; 21. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin

Published
2020
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41. Breast Cancer Screening and Diagnosis: A Synopsis of the European Breast Guidelines

Author

Schunemann, HJ, Lerda, D, Quinn, C, Follmann, M, Alonso-Coello, P, Rossi, PG, Lebeau, A, Nystrom, L, Broeders, M, Ioannidou-Mouzaka, L, Duffy, SW, Borisch, B, Fitzpatrick, P, Hofvind, S, Castells, X, Giordano, L, Canelo-Aybar, C, Warman, S, Mansel, R, Sardanelli, F, Parmelli, E, Grawingholt, A, Saz-Parkinson, Z, and ECIBC Contributor Grp

Abstract

Description: The European Commission Initiative for Breast Cancer Screening and Diagnosis guidelines (European Breast Guidelines) are coordinated by the European Commission's Joint Research Centre. The target audience for the guidelines includes women, health professionals, and policymakers. Methods: An international guideline panel of 28 multidisciplinary members, including patients, developed questions and corresponding recommendations that were informed by systematic reviews of the evidence conducted between March 2016 and December 2018. GRADE (Grading of Recommendations Assessment, Development and Evaluation) Evidence to Decision frameworks were used to structure the process and minimize the influence of competing interests by enhancing transparency. Questions and recommendations, expressed as strong or conditional, focused on outcomes that matter to women and provided a rating of the certainty of evidence. Recommendations: This synopsis of the European Breast Guidelines provides recommendations regarding organized screening programs for women aged 40 to 75 years who are at average risk. The recommendations address digital mammography screening and the addition of hand-held ultrasonography, automated breast ultrasonography, or magnetic resonance imaging compared with mammography alone. The recommendations also discuss the frequency of screening and inform decision making for women at average risk who are recalled for suspicious lesions or who have high breast density.

Published
2020

44. Approaches of integrating the development of guidelines and quality indicators: a systematic review

Author

Langendam, M.W., Piggott, T., Nothacker, M., Agarwal, A., Armstrong, D., Baldeh, T., Braithwaite, J., Martins, C., Darzi, A., Etxeandia, I., Florez, I., Hoving, J., Karam, S.G., Kötter, T., Meerpohl, J.J., Mustafa, R.A., Muti-Schünemann, G.E.U., Wees, P.J. van der, Follmann, M., Schünemann, H.J., Langendam, M.W., Piggott, T., Nothacker, M., Agarwal, A., Armstrong, D., Baldeh, T., Braithwaite, J., Martins, C., Darzi, A., Etxeandia, I., Florez, I., Hoving, J., Karam, S.G., Kötter, T., Meerpohl, J.J., Mustafa, R.A., Muti-Schünemann, G.E.U., Wees, P.J. van der, Follmann, M., and Schünemann, H.J.

Abstract

Contains fulltext : 225833.pdf (publisher's version ) (Open Access), BACKGROUND: Guidelines and quality indicators (for example as part of a quality assurance scheme) aim to improve health care delivery and health outcomes. Ideally, the development of quality indicators should be grounded in evidence-based, trustworthy guideline recommendations. However, anecdotally, guidelines and quality assurance schemes are developed independently, by different groups of experts who employ different methodologies. We conducted an extension and update of a previous systematic review to identify, describe and evaluate approaches to the integrated development of guidelines and related quality indicators. METHODS: On May 24th, 2019 we searched in Medline, Embase and CINAHL and included studies if they reported a methodological approach to guideline-based quality indicator development and were published in English, French, or German. RESULTS: Out of 16,034 identified records, we included 17 articles that described a method to integrate guideline recommendations development and quality indicator development. Added to the 13 method articles from original systematic review we included a total 30 method articles. We did not find any evaluation studies. In most approaches, guidelines were a source of evidence to inform the quality indicator development. The criteria to select recommendations (e.g. level of evidence or strength of the recommendation) and to generate, select and assess quality indicators varied widely. We found methodological approaches that linked guidelines and quality indicator development explicitly, however none of the articles reported a conceptual framework that fully integrated quality indicator development into the guideline process or where quality indicator development was part of the question formulation for developing the guideline recommendations. CONCLUSIONS: In our systematic review we found approaches which explicitly linked guidelines with quality indicator development, nevertheless none of the articles reported a comprehen

Published
2020

49. Recommendations from the European Commission Initiative on Breast Cancer on multigene tests to guide the use of adjuvant chemotherapy in patients who have hormone receptor positive, HER-2 negative, lymph node negative or up to 3 lymph nodes positive invasive breast cancer

Author

Rossi, P.Giorgi, primary, Lebeau, A., additional, Canelo-Aybar, C., additional, Rivera, M.C. Posso, additional, Comas, D.Rigau, additional, Quinn, C., additional, Coello, P.Alonso, additional, McGarrigle, H., additional, Warman, S., additional, Broeders, M., additional, Duffy, S., additional, Langendam, M.W., additional, Gräwingholt, A., additional, Follmann, M., additional, Saz-Parkinson, Z., additional, and Schünemann, H., additional

Published
2020
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