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1,070 results on '"Fodor, J."'

4. A class of aggregation functions encompassing two-dimensional OWA operators

Author

Bustince, H., Calvo, T., De Baets, B., Fodor, J., Mesiar, R., Montero, Javier, Paternain, D., Pradera, A., Bustince, H., Calvo, T., De Baets, B., Fodor, J., Mesiar, R., Montero, Javier, Paternain, D., and Pradera, A.

Abstract

In this paper we prove that, under suitable conditions, Atanassov’s Ka operators, which act on intervals, provide the same numerical results as OWA operators of dimension two. On one hand, this allows us to recover OWA operators from Ka operators. On the other hand, by analyzing the properties of Atanassov’s operators, we can generalize them. In this way, we introduce a class of aggregation functions – the generalized Atanassov operators – that,in particular, include two-dimensional OWA operators. We investigate under which conditions these generalized Atanassov operators satisfy some properties usually required for aggregation functions, such as bisymmetry, strictness, monotonicity, etc. We also show that if we apply these aggregation functions to interval-valued fuzzy sets, we obtain an ordered family of fuzzy sets., Depto. de Estadística e Investigación Operativa, Fac. de Ciencias Matemáticas, TRUE, pub

Published
2023

20. Transcriptome-based screening of ion channels and transporters in a migratory chondroprogenitor cell line isolated from late-stage osteoarthritic cartilage

Author

Matta, C. (Csaba), Lewis, R. (Rebecca), Fellows, C. (Christopher), Diszhazi, G. (Gyula), Almassy, J. (Janos), Miosge, N. (Nicolai), Dixon, J. (James), Uribe, M. C. (Marcos C.), May, S. (Sean), Poliska, S. (Szilard), Barrett-Jolley, R. (Richard), Fodor, J. (Janos), Szentesi, P. (Peter), Hajdú, T. (Tibor), Keller-Pinter, A. (Aniko), Henslee, E. (Erin), Labeed, F. H. (Fatima H.), Hughes, M. P. (Michael P.), and Mobasheri, A. (Ali)

Subjects
osteoarthritis, transcriptomics, chondrocyte, channelome, chondroprogenitor, cartilage, mesenchymal stem cell
Abstract

Chondrogenic progenitor cells (CPCs) may be used as an alternative source of cells with potentially superior chondrogenic potential compared to mesenchymal stem cells (MSCs), and could be exploited for future regenerative therapies targeting articular cartilage in degenerative diseases such as osteoarthritis (OA). In this study, we hypothesised that CPCs derived from OA cartilage may be characterised by a distinct channelome. First, a global transcriptomic analysis using Affymetrix microarrays was performed. We studied the profiles of those ion channels and transporter families that may be relevant to chondroprogenitor cell physiology. Following validation of the microarray data with quantitative reverse transcription-polymerase chain reaction, we examined the role of calcium-dependent potassium channels in CPCs and observed functional large-conductance calcium-activated potassium (BK) channels involved in the maintenance of the chondroprogenitor phenotype. In line with our very recent results, we found that the KCNMA1 gene was upregulated in CPCs and observed currents that could be attributed to the BK channel. The BK channel inhibitor paxilline significantly inhibited proliferation, increased the expression of the osteogenic transcription factor RUNX2, enhanced the migration parameters, and completely abolished spontaneous Ca2+ events in CPCs. Through characterisation of their channelome we demonstrate that CPCs are a distinct cell population but are highly similar to MSCs in many respects. This study adds key mechanistic data to the in-depth characterisation of CPCs and their phenotype in the context of cartilage regeneration.

Published
2021

40. First report of a 'Candidatus Phytoplasma asteris'‐related strain (16SrI‐B) associated with three Sempervivum cultivars in Hungary.

Author

Viczián, O., Fodor, J., Ágoston, J., and Mergenthaler, E.

Subjects
CULTIVARS, CANDIDATUS, BIOINFORMATICS software
Abstract

The 16S rRNA gene sequences were identical from all plants of all three varieties and had 99.95% identity with Onion yellows phytoplasma strain OY-M (AP006628) and ' I Muscari botryoides i ' aster yellows phytoplasma (GenBank ON564434.1) from the ' I Candidatus i Phytoplasma asteris' (16SrI-B) subgroup (Figure 2). Keywords: aster yellows; houseleek; phytoplasma EN aster yellows houseleek phytoplasma 1 3 3 09/28/23 20230701 NES 230701 Plants belonging to the genus I Sempervivum i (houseleek) are succulent perennials forming mats composed of thick, rubbery leaves in rosettes. First report of a "Candidatus Phytoplasma asteris"-related strain (16SrI-B) associated with three Sempervivum cultivars in Hungary. [Extracted from the article]

Published
2023
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