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1. The ACAMTO study—impact of add-on osteopathic treatment on adolescent patients with anorexia nervosa: study protocol for a randomized controlled trial

Author

Aurélie Letranchant, Yunkyung Kim-de Montebello, Corinne Dugré-Le bigre, Agathe Wagner, Florence Curt, Jérôme Silva, Isabelle Nicolas, Pablo Votadoro, Nina Kalindjian, Anna Korchonnoff, Andréa Gutierre, Ana Beatriz Novelli, Alexandra Pham-Scottez, and Maurice Corcos

Subjects
Anorexia nervosa, Body approach, Interoception, Osteopathic medicine, Osteopathic treatment, Randomized controlled trial, Medicine (General), R5-920
Abstract

Abstract Background Anorexia nervosa (AN) mainly affects women (sex ratio 1/10) and most often starts during adolescence. The prognosis of AN remains poor (10% of deaths and high risk of chronicity). Body dissatisfaction, disturbances in recognition and identification of body sensations are some of the key symptoms of AN. However, there is a contrast between this consensual observation of body image disorders in AN, and the relative deficit of specifically targeted body treatments. Our proposal for a body approach specifically dedicated to AN is based on the understanding that posture, breathing, muscle tension and body perception are closely linked to our psychological and emotional state and are therefore disturbed in patients with AN. The purpose of this monocentric randomized controlled trial is to evaluate if a targeted osteopathic protocol treatment for AN in addition to treatment as usual (TAU) is significantly more effective than TAU alone. Methods In total, 72 patients meeting the inclusion criteria will be randomly assigned to one of the two treatment groups: one receiving the specific osteopathic treatment targeted for AN in addition to the TAU (group A) and the other one, receiving TAU only (group B). The patients in group A will receive 5 30-min osteopathic treatment sessions. Soft specific palpatory techniques on the diaphragm, digestive system and cervical region will be performed. The TAU is defined by the multidisciplinary approach recommended by the French health high authority. The primary outcome is the evaluation of interoceptive sensibility and secondary outcomes include clinical and psychopathology-related symptoms with assessment of somatic dysfunctions’ evolution. A qualitative study will also be carried out, applying the Interpretative Phenomenological Analysis method. Patients will be included for a maximum of 14 weeks between the inclusion time and the last evaluation. Discussion If the results of the study are positive (statistically significant efficacy of this osteopathic treatment protocol), the study will provide arguments in favor of osteopathic sessions as a possible non-invasive additional treatment option in the multidisciplinary care approach for patients with AN. Trial registration ClinicalTrials.gov ID: NCT04666415 , Release Date: December 11, 2020; N° ID-RCB: 2019-A02613-54.

Published
2021
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2. Decreased Immune Response in Alexithymic Women: A One-Year Longitudinal Study

Author

Olivier Guilbaud, Claire Perrin, Florence Curt, Gérard Chaouat, Corinne Dugré-Le Bigre, Martine Strebler, Catherine Touitou, and Maurice Corcos

Subjects
alexithymia, cytokines, immunity, psychosomatic medicine, psychoneuroimmunology, Psychiatry, RC435-571
Abstract

Although previous cross-sectional studies suggested significantly dysregulated immune response in alexithymia, there is a lack of longitudinal studies. We sought to determine the reliability of the reported relationship between alexithymia and decreased immune response in a longitudinal study. Thirty-eight healthy women who had participated in a cross-sectional study were recontacted 1-year later. Of this sample, 26 were finally included: 13 females who had been found to be alexithymic, and 13 females who were classified as non-alexithymic under the 20-item Toronto Alexithymia Scale during the first phase of the study. A year later, they were still healthy women without any psychiatric disorders, their ages now ranging from 19 to 28 years old. Lymphocyte subset counts (CD4, CD8), in vitro production of interleukin 1β (IL-1β), IL-2, IL-4, and IL-10 by phytohemagglutinin stimulated peripheral blood lymphocytes, as well as serum cortisol levels, were compared between women with and without alexithymia. One-year later, alexithymic women still had significantly lowered in vitro production of IL-2 and IL-4, with lowered IL-2/IL-10 ratio and a reduced percentage of CD4. This is the first ever published study assessing cytokine production during a follow-up of alexithymics. Although our results should be interpreted with caution due the small sample size, they suggest a sustained reduction in both major type 1 and type 2 cytokines while the former seems to be more affected. The potential long-term health impact, if any, is still to be determined.

Published
2021
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3. Predictive factors for outcome in adolescents with anorexia nervosa: To what extent does parental Expressed Emotion play a role?

Author

Jeanne Duclos, Géraldine Dorard, Solange Cook-Darzens, Florence Curt, Sophie Faucher, Sylvie Berthoz, Bruno Falissard, and Nathalie Godart

Subjects
Medicine, Science
Abstract

In studies on family therapy in Anorexia Nervosa, family relationships, as assessed by Expressed Emotion, have been associated with outcome. Our aim was to explore the contribution of Expressed Emotion as a predictor of 18-month outcome, above and beyond the usual predictive factors. Sixty adolescent girls suffering from Anorexia Nervosa and their parents were assessed at baseline and 18 months later. Levels of Expressed Emotion were evaluated in both parents with the Five-Minute Speech Sample. After controlling for treatment group and initial clinical status, high maternal Emotional Over-Involvement at baseline was significantly associated with better clinical state. More precisely, high maternal Emotional Over-Involvement was associated with higher nutritional status, lower eating disorder severity and fewer re-hospitalizations 18 months later. No associations were found with paternal levels of Expressed Emotion. Therefore, our study confirmed the importance of taking into account both maternal and paternal Expressed Emotion. Our results also underlined that high maternal Emotional Over-Involvement plays a positive role in the outcome of Anorexia Nervosa and needs to be explored further.

Published
2018
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4. A randomized controlled trial of adjunctive family therapy and treatment as usual following inpatient treatment for anorexia nervosa adolescents.

Author

Nathalie Godart, Sylvie Berthoz, Florence Curt, Fabienne Perdereau, Zoé Rein, Jenny Wallier, Anne-Sophie Horreard, Irène Kaganski, Réjane Lucet, Frédéric Atger, Maurice Corcos, Jacques Fermanian, Bruno Falissard, Martine Flament, Ivan Eisler, and Philippe Jeammet

Subjects
Medicine, Science
Abstract

UNLABELLED: Research on treatments in anorexia nervosa (AN) is scarce. Although most of the therapeutic programs used in 'real world practice' in AN treatment resort to multidisciplinary approaches, they have rarely been evaluated. OBJECTIVE: To compare two multidimensional post-hospitalization outpatients treatment programs for adolescents with severe AN: Treatment as Usual (TAU) versus this treatment plus family therapy (TAU+FT). METHOD: Sixty female AN adolescents, aged 13 to 19 years, were included in a randomized parallel controlled trial conducted from 1999 to 2002 for the recruitment, and until 2004 for the 18 months follow-up. Allocation to one of the two treatment groups (30 in each arm) was randomised. The TAU program included sessions for the patient alone as well as sessions with a psychiatrist for the patient and her parents. The TAU+FT program was identical to the usual one but also included family therapy sessions targeting intra-familial dynamics, but not eating disorder symptoms. The main Outcome Measure was the Morgan and Russell outcome category (Good or Intermediate versus Poor outcome). Secondary outcome indicators included AN symptoms or their consequences (eating symptoms, body mass index, amenorrhea, number of hospitalizations in the course of follow-up, social adjustment). The evaluators, but not participants, were blind to randomization. RESULTS: At 18 months follow-up, we found a significant group effect for the Morgan and Russell outcome category in favor of the program with family therapy (Intention-to-treat: TAU+FT :12/30 (40%); TAU : 5/29 (17.2%) p = 0.05; Per Protocol analysis: respectively 12/26 (46.2%); 4/27 (14.8%), p = 0.01). Similar group effects were observed in terms of achievement of a healthy weight (i.e., BMI≥10(th) percentile) and menstrual status. CONCLUSIONS: Adding family therapy sessions, focusing on intra-familial dynamics rather than eating symptomatology, to a multidimensional program improves treatment effectiveness in girls with severe AN. TRIAL REGISTRATION: Controlled-trials.com ISRCTN71142875.

Published
2012
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5. The ACAMTO study—impact of add-on osteopathic treatment on adolescent patients with anorexia nervosa: study protocol for a randomized controlled trial

Author

Isabelle Nicolas, Ana Beatriz Novelli, Andréa Gutierre, Yunkyung Kim-de Montebello, Aurélie Letranchant, Corinne Dugré-Le Bigre, Maurice Corcos, Jérôme Silva, Pablo Votadoro, Nina Kalindjian, Florence Curt, Anna Korchonnoff, Agathe Wagner, and Alexandra Pham-Scottez

Subjects
medicine.medical_specialty, Medicine (General), Adolescent, Medicine (miscellaneous), law.invention, Interoception, Treatment and control groups, Study Protocol, Body approach, Osteopathic treatment, R5-920, Randomized controlled trial, Multidisciplinary approach, law, Muscle tension, medicine, Humans, Pharmacology (medical), Randomized Controlled Trials as Topic, Interpretative phenomenological analysis, business.industry, Anorexia nervosa, Osteopathic medicine in the United States, Treatment Outcome, Osteopathic medicine, Anorexia nervosa (differential diagnoses), Physical therapy, Breathing, Female, business
Abstract

Background Anorexia nervosa (AN) mainly affects women (sex ratio 1/10) and most often starts during adolescence. The prognosis of AN remains poor (10% of deaths and high risk of chronicity). Body dissatisfaction, disturbances in recognition and identification of body sensations are some of the key symptoms of AN. However, there is a contrast between this consensual observation of body image disorders in AN, and the relative deficit of specifically targeted body treatments. Our proposal for a body approach specifically dedicated to AN is based on the understanding that posture, breathing, muscle tension and body perception are closely linked to our psychological and emotional state and are therefore disturbed in patients with AN. The purpose of this monocentric randomized controlled trial is to evaluate if a targeted osteopathic protocol treatment for AN in addition to treatment as usual (TAU) is significantly more effective than TAU alone. Methods In total, 72 patients meeting the inclusion criteria will be randomly assigned to one of the two treatment groups: one receiving the specific osteopathic treatment targeted for AN in addition to the TAU (group A) and the other one, receiving TAU only (group B). The patients in group A will receive 5 30-min osteopathic treatment sessions. Soft specific palpatory techniques on the diaphragm, digestive system and cervical region will be performed. The TAU is defined by the multidisciplinary approach recommended by the French health high authority. The primary outcome is the evaluation of interoceptive sensibility and secondary outcomes include clinical and psychopathology-related symptoms with assessment of somatic dysfunctions’ evolution. A qualitative study will also be carried out, applying the Interpretative Phenomenological Analysis method. Patients will be included for a maximum of 14 weeks between the inclusion time and the last evaluation. Discussion If the results of the study are positive (statistically significant efficacy of this osteopathic treatment protocol), the study will provide arguments in favor of osteopathic sessions as a possible non-invasive additional treatment option in the multidisciplinary care approach for patients with AN. Trial registration ClinicalTrials.gov ID: NCT04666415, Release Date: December 11, 2020; N° ID-RCB: 2019-A02613-54.

Published
2021

6. Long‐term follow‐up of a randomized controlled trial comparing systemic family therapy (FT‐S) added to treatment as usual (TAU) with TAU alone in adolescents with anorexia nervosa

Author

Nathalie Godart, Géraldine Dorard, Jeanne Duclos, Florence Curt, Irène Kaganski, Lisa Minier, Maurice Corcos, Bruno Falissard, Ivan Eisler, Philippe Jeammet, Sylvie Berthoz, Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Laboratoire de Psychopathologie et Processus de Santé (LPPS (URP_4057)), Université Paris Cité (UPCité), Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 (SCALab), Université de Lille-Centre National de la Recherche Scientifique (CNRS), Hôpital Saint Vincent de Paul de Lille, Groupement des Hôpitaux de l'Institut Catholique de Lille (GHICL), Université catholique de Lille (UCL)-Université catholique de Lille (UCL), Dept. of Psychiatry for Adolescents and Young Adults, Faculté de Médecine, Site Institut Mutualiste Montsouris, Université Paris Descartes - Paris 5 (UPD5), Fondation santé des Etudiants de France, Fondation Santé des Etudiants de France, Institut Mutualiste de Montsouris (IMM), Laboratoire de Psychologie Clinique, Psychopathologie, Psychanalyse (PCPP - EA 4056), AP-HP. Université Paris Saclay, King‘s College London, South London and Maudsley NHS Foundation Trust, Institut de Neurosciences cognitives et intégratives d'Aquitaine (INCIA), Université Bordeaux Segalen - Bordeaux 2-Université Sciences et Technologies - Bordeaux 1 (UB)-SFR Bordeaux Neurosciences-Centre National de la Recherche Scientifique (CNRS), and Institut mutualiste Monsouris (IMM)

Subjects
Anorexia Nervosa, Adolescent, [SDV]Life Sciences [q-bio], Feeding and Eating Disorders, Psychiatry and Mental health, Treatment Outcome, Pediatrics, Perinatology and Child Health, Ambulatory Care, Developmental and Educational Psychology, Humans, Female, Family Therapy, Follow-Up Studies, Randomized Controlled Trials as Topic
Abstract

Randomized controlled trials showed the efficacy of family therapy for anorexia nervosa during adolescence, but studies examining its long-term beneficial effect are still needed. This article presents the results of a 54-month post-randomization follow-up of a previously reported randomized controlled trial that compared two post-hospitalization outpatient treatment programs: Treatment As Usual alone versus Systemic Family Therapy added to Treatment As Usual.A consecutive series of 60 female adolescents with anorexia nervosa (DSM-IV) were randomized (30 per group). During the first 18 months, in the Treatment As Usual group, subjects received a multidisciplinary treatment. In the other group, Systemic Family Therapy sessions targeting intra-familial dynamics were added to Treatment As Usual. At 54 months, the primary outcome was defined using the Morgan and Russell global Outcome Categories (Good or Intermediate versus Poor). Secondary outcomes were the Global Outcome Assessment Schedule score, body mass index, amenorrhea, number of hospitalizations, eating disorder symptoms, psychopathological features, and family functioning. Analyses were carried out using an Intention-To-Treat with the Last Observation Carried Forward procedure. Data of 59/60 subjects were available.At 54 months, significant effects in favor of adding Systemic Family Therapy to Treatment As Usual were shown for the Global Outcome Categories (60% of Good/Intermediate versus 31% in the control group, p = .026), mean body mass index (p = .048), resumption of menses (70.0% vs. 40% p = .020), and mental state score (p = .010). Family cohesion scores were lower in the Systemic Family Therapy group (p = .040).Adding Systemic Family Therapy focusing on intra-familial dynamics to a multidimensional outpatient treatment program appeared to lead to a better long-term outcome in young women who suffered from severe anorexia nervosa during adolescence.

Published
2022
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7. A key for perinatal depression early diagnosis: The body dissatisfaction

Author

Henri Cohen, Guillaume Legendre, Elise Riquin, Isabelle Nicolas, Maurice Corcos, Corinne Dugre Lebigre, Nathalie Godart, Florence Curt, and Claire Lamas

Subjects
Adult, Longitudinal study, medicine.medical_specialty, Emotions, Anxiety, Depression, Postpartum, Feeding and Eating Disorders, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, Risk Factors, Body Image, medicine, Humans, Longitudinal Studies, Psychiatry, Depression (differential diagnoses), Psychiatric Status Rating Scales, business.industry, Postpartum Period, medicine.disease, 030227 psychiatry, Psychiatry and Mental health, Clinical Psychology, Eating disorders, Body shape questionnaire, Early Diagnosis, Edinburgh Postnatal Depression Scale, Female, business, 030217 neurology & neurosurgery, Perinatal Depression, Body dissatisfaction
Abstract

To test if the evaluation of body dissatisfaction by images could be an interesting tool to detect perinatal depression early in pregnancy, questioning patients about their body image instead of their depressive symptoms.A sample of 457 women was recruited in a longitudinal study. Three evaluations were performed at the 4th and 8th months of pregnancy and during post-partum. During these evaluations, sociodemographic data were collected and psychiatric scales were completed, including Edinburgh Postnatal Depression Scale (EPDS), Eating Disorder Examination-Questionnaire (EDE-Q), Pictorial Body Image Scale (PBIS) and Body Shape Questionnaire (BSQ).33% of the women who were unsatisfied with their body image suffered from perinatal depression vs. 11.3% of the women who were not (p 0.0001). The risk of perinatal depression was 4 times higher in women dissatisfied with their body image (p 0.001) if unintended pregnancy and age are taken into account and is 3 times significantly higher in women with higher levels of eating disorders symptoms (p 0.001) if unintended pregnancy and age are taken into account. Our sample was a privileged population, as often in the literature.The administration of a simple scale (PBIS) during an early visit during pregnancy allows detecting perinatal depression. This should prevent the stigmatization of women during pregnancy and reduce the risk of not diagnosing depression during pregnancy and post-partum.

Published
2019
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8. Troubles bipolaires et anorexie mentale : une étude clinique

Author

Jeanne Duclos, L Radon, Florence Curt, Nathalie Godart, M. Valentin, Institut Mutualiste de Montsouris (IMM), Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Université Paris Descartes - Faculté de Médecine (UPD5 Médecine), and Université Paris Descartes - Paris 5 (UPD5)

Subjects
03 medical and health sciences, Psychiatry and Mental health, 0302 clinical medicine, Arts and Humanities (miscellaneous), [SDV]Life Sciences [q-bio], 3. Good health, 030227 psychiatry
Abstract

Resume Contexte L’anorexie mentale (AM) presente frequemment des comorbidites avec les troubles de l’humeur, en particulier, la depression, par contre les antecedents individuels et/ou familiaux de troubles bipolaires (BP) a, quant a lui, ete peu etudie. Objectifs Cette etude a pour objectifs : (1) d’evaluer, d’une part, la frequence des troubles bipolaires aupres de patients souffrant d’anorexie mentale hospitalises a l’adolescence et leurs parents ; (2) et d’autre part, de rechercher si les patientes aux antecedents personnels et/ou familiaux de trouble bipolaire presentent des caracteristiques particulieres quant a l’expression clinique de leur anorexie mentale, leurs antecedents, les diagnostics secondaires poses, les traitements prescrits. Methode Au total, 97 patientes, âgees entre 13 et 20 ans, hospitalisees pour anorexie mentale ont ete evaluees. Les diagnostics anorexie mentale et trouble bipolaire ont ete poses selon les criteres du DSM IV-TR. Resultats Une frequence elevee de troubles bipolaires de type II et de type V a ete observee. Les patientes souffrant d’anorexie mentale et presentant des antecedents personnels ou familiaux de trouble bipolaire ont un debut plus precoce de l’anorexie mentale, un nombre d’hospitalisations plus important, un delai plus long entre le debut de l’anorexie mentale et l’hospitalisation un nombre plus eleve de tentatives de suicide et presentent davantage de comorbidites psychiatriques. Conclusion La presence d’une comorbidite anorexie mentale–trouble bipolaire semble importante et liee a la severite de l’anorexie mentale.

Published
2019
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9. Mood disorders in eating disorder patients: Prevalence and chronology of ONSET

Author

Martine F. Flament, Jean-Luc Venisse, Ph Jeammet, L. Radon, F. Lang, Gwenolé Loas, Paul Bizouard, Nathalie Godart, Maurice Corcos, Florence Curt, Olivier Halfon, Fabienne Perdereau, and Jeanne Duclos

Subjects
Adult, medicine.medical_specialty, Anorexia Nervosa, Adolescent, Comorbidity, behavioral disciplines and activities, Feeding and Eating Disorders, Young Adult, Prevalence of mental disorders, mental disorders, Prevalence, medicine, Humans, Bulimia Nervosa, Psychiatry, Major depressive episode, Mini-international neuropsychiatric interview, Depressive Disorder, Mood Disorders, Bulimia nervosa, medicine.disease, Psychiatry and Mental health, Clinical Psychology, Eating disorders, Mood disorders, Anorexia nervosa (differential diagnoses), Major depressive disorder, Female, France, medicine.symptom, Psychology
Abstract

Objectives In a clinical population, we estimated the frequency of mood disorders among 271 patients suffering from Anorexia Nervosa (AN) and Bulimia Nervosa (BN) in comparison to a control group matched for age and gender. Method The frequency of mood disorders was measured using the Mini International Neuropsychiatric Interview (MINI), DSM-IV version. Results Mood disorders were more frequent among eating disorder (ED) patients than among controls, with a global prevalence of the order of 80% for each ED group. The majority of the mood disorders comorbid with ED were depressive disorders (MDD and dysthymia). The relative chronology of onset of these disorders was equivocal, because mood disorders in some cases preceded and in others followed the onset of the eating disorders. Limitations Our sample was characterized by patients with severe ED and high comorbidities, and thus do not represent the entire population of AN or BN. This also may have resulted in an overestimation of prevalence. Conclusion Mood disorders appear significantly more frequently in patients seeking care for ED than in controls. These results have implications for the assessment and treatment of ED patients, and for the aetio-pathogenesis of these disorders.

Published
2015
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10. Expressed emotion in anorexia nervosa: What is inside the 'black box'?

Author

Sylvie Berthoz, Bruno Falissard, Jeanne Duclos, Sophie Faucher, Nathalie Godart, Florence Curt, and Géraldine Dorard

Subjects
Parents, Anorexia Nervosa, Adolescent, lcsh:RC435-571, Developmental psychology, Young Adult, Alexithymia, lcsh:Psychiatry, medicine, Humans, Expressed emotion, Parent-Child Relations, Young adult, Depression (differential diagnoses), Parenting, Depression, Social anxiety, medicine.disease, Expressed Emotion, Psychiatry and Mental health, Clinical Psychology, Anorexia nervosa (differential diagnoses), Anxiety, Female, medicine.symptom, Psychology, Body mass index
Abstract

Objective Expressed Emotion has been called a “black box”, since little is known about contributing factors. The aim of this study was to examine which parental and which patient/illness-related characteristics contribute to maternal and paternal Expressed Emotion levels. Method Sixty adolescent girls with Anorexia Nervosa (AN) and their parents completed instruments that evaluate characteristics of the adolescent's illness and patient/parental psychological characteristics (depression; anxiety; obsession–compulsion; social anxiety and alexithymia). The following illness-related characteristics were recorded: age at AN onset, duration of illness, AN subtype (restrictive AN-R vs. purging type AN-B), current Body Mass Index (BMI) (in kg/m2), minimum lifetime BMI and number of previous hospitalizations, the Global Outcome Assessment Scale total score. Levels of Expressed Emotion were assessed for the two parents using the Five-Minute Speech Sample. Results Less than 30% of the parents in our sample expressed high levels of Critical EE and Emotional Over-Involvement. Our main findings indicate that maternal Criticism (Critical EE levels, Critical Comments, Dissatisfaction) and the sub-dimensions of maternal Emotional Over-Involvement (EOI EE) (Statement of loving Attitudes and Excessive Details about the past) were related both to the severity of the daughters' clinical state and to maternal psychological functioning. Only paternal levels of anxiety explained paternal Dissatisfaction, EOI EE and Statement of loving Attitudes. Discussion Parental psychological functioning and the severity of the daughters' clinical state have an impact on the family relationships. These elements should be targeted by individual treatment for parents where necessary, and by psycho-educational sessions about Anorexia Nervosa for parents generally.

Published
2014
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11. Contents Vol. 46, 2013

Author

Michael Katzev, Siegfried Kasper, Martin E. Franklin, Paul Fährmann, Nathalie Godart, Sören Kliem, Axel Krug, Raffaella Calati, Géraldine Dorard, Sarah Vibert, Alessandro Serretti, Suzanne Abraham, William Tak-Lam Lo, Julien Mendlewicz, Winnie W. N. Ho, Stefan Roepke, Alexandre Apfel, Christoph Kröger, Anne-Solène Maria, Michael Rufer, Melanie Vonau, Larry Davidson, Arne Nagels, Mirjam Stratmann, Hanspeter Moergeli, Arnoud Arntz, Christian Schales, Lena Turner, Othman Sentissi, Joachim Kosfelder, Stefan C. A. Hegemann, Michael Gar-Chung Yiu, Steffi Weidt, Rüdiger Müller-Isberner, Daniela Amital, Tilo Kircher, Daniel Souery, Beth Mugno, Satz Mengensatzproduktion, Niki Antypa, Florence Curt, Jeanne Duclos, Marcus Y. L. Chiu, Astrid von Lojewski, Druck Reinhardt Druck Basel, Dominik Straumann, Joseph Zohar, Monnica T. Williams, Sonja von Rimscha, U. Moser, Tobias Hornig, Anna Fisher, Michael Frauenheim, Sayed Ghazi, Fabienne Perdereau, Sonya Faber, and Zoé Rein

Subjects
Psychiatry and Mental health, Clinical Psychology, Anthropology, Psychology
Published
2013
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12. Are lifetime affective disorders predictive of long-term outcome in severe adolescent anorexia nervosa?

Author

Jeanne Duclos, T. Hubert, Florence Curt, Sarah Vibert, B. Carrot, Nathalie Godart, and L Radon

Subjects
Adult, Male, medicine.medical_specialty, Anorexia Nervosa, Adolescent, Comorbidity, behavioral disciplines and activities, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Quality of life, mental disorders, Developmental and Educational Psychology, medicine, Child and adolescent psychiatry, Humans, Psychiatry, Depression (differential diagnoses), Mood Disorders, General Medicine, medicine.disease, 030227 psychiatry, Psychiatry and Mental health, Treatment Outcome, Mood disorders, Anorexia nervosa (differential diagnoses), Pediatrics, Perinatology and Child Health, Quality of Life, Anxiety, Female, medicine.symptom, Psychology, 030217 neurology & neurosurgery, Agoraphobia, Clinical psychology
Abstract

Depression and anxiety are commonly associated with anorexia nervosa (AN) and contribute to difficulties in social integration, a negative factor for outcome in AN. The link between those disorders and AN has been poorly studied. Thus, our objective was to investigate (1) the link between outcome nine years after hospitalisation for AN and the occurrence of lifetime anxious or depressive comorbidities; (2) the prognostic value of these comorbidities on patient outcome; 181 female patients were hospitalised for AN (between 13 and 22 years old), and were re-evaluated for their psychological, dietary, physical and social outcomes, from 6 to 12 years after their hospitalisation. The link between anxious and depressive disorders (premorbid to AN and lifetime) and the outcome assessment criteria were tested through multivariate analyses; 63% of the participants had good or intermediate outcome, 83% had presented at least one anxiety or depression disorder in the course of their lives, half of them before the onset of AN. Premorbid obsessive compulsive disorders (OCD), BMI at admission, and premenarchal AN all contribute to poor prognosis. Social phobia and agoraphobia affect the subjects' quality of life and increase eating disorder symptoms. These results encourage a systematic assessment of, and care for, anxiety and depression comorbidities among female adolescent patients with a particular focus on premorbid OCD.

Published
2016

13. Is major depressive episode related to anxiety disorders in anorexics and bulimics?

Author

Fabienne Perdereau, Jean Luc Venisse, François Lang, Gwenolé Loas, Maurice Corcos, Martine F. Flament, Zoé Rein, N.-T. Godart, Philippe Jeammet, Paul Bizouard, Florence Curt, and Olivier Halfon

Subjects
Adult, medicine.medical_specialty, Anorexia Nervosa, lcsh:RC435-571, Comorbidity, Anorexia nervosa, behavioral disciplines and activities, lcsh:Psychiatry, Interview, Psychological, mental disorders, medicine, Humans, Major depressive episode, Psychiatry, Bulimia Nervosa, Mini-international neuropsychiatric interview, Depressive Disorder, Major, Panic disorder, medicine.disease, Anxiety Disorders, Psychiatry and Mental health, Clinical Psychology, Eating disorders, Multivariate Analysis, Anxiety, Female, medicine.symptom, Psychology, Anxiety disorder
Abstract

Objective: To determine whether the presence of anxiety disorders is related to depressive comorbidity in subjects with eating disorders (ED), while taking into account certain variables that may be related to depression (subjects’ age, ED duration, prior incidents of anorexia nervosa in bulimic subjects, inpatient or outpatient status, nutritional state [as measured by body mass index]). Method: We evaluated the frequency of depressive disorders in 271 subjects presenting with a diagnosis of either anorexia nervosa or bulimia, using the Mini International Neuropsychiatric Interview, DSM-IV version. Results: A multivariate analysis reveals that anxiety disorders do not all have the same influence in terms of risk of onset of major depressive episode in anorexics and bulimics when adjusted on variables related to depression. Conclusion: Depression in subjects with ED can be explained in part by comorbidity with obsessive-compulsive disorder, generalized anxiety, social phobia, and panic disorder. D 2006 Published by Elsevier Inc.

Published
2006

14. Testing the Working Alliance Inventory (WAI) in a French primary care setting

Author

Jacques Fermanian, Antonia Bifulco, Florence Curt, and Nicole Guedeney

Subjects
Adult, Male, Social Work, Health (social science), Adolescent, Social Psychology, Psychometrics, Epidemiology, Test validity, Surveys and Questionnaires, Humans, Primary Health Care, Discriminant validity, Construct validity, Social environment, Middle Aged, Mental health, Exploratory factor analysis, Psychiatry and Mental health, Alliance, Female, Factor Analysis, Statistical, Psychology, Social psychology, Forecasting, Clinical psychology
Abstract

Working alliance has shown a predictive value of the outcome in different therapeutic settings but was not yet studied in a non-medical setting. The predictive value and the factor structure of the Working Alliance Inventory (WAI) [36-item client version; as reported by Horvath and Greenberg (J Couns Psychol 36:223–233, 1989)] were studied in a French primary care setting on a sample of 130 adults accessing social services. The WAI total score completed after the first meeting was positively predictive of quality of the working alliance 4 months later. An exploratory factor analysis produced two orthogonal factors which explained 45.12% of the total variance: a first factor (23 items) labelled ‘positive expectations about the usefulness of help’ and a second factor (13 items) labelled ‘absence of suspicion about the effects of help’. The WAI is shown to be applicable to primary care social work settings to measure the working alliance phenomenon and predict disruption of practitioner–client relationship.

Published
2005
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15. La fréquence des troubles anxio-dépressifs diffère-t-elle entre les types diagnostiques d’anorexie mentale et de boulimie ?

Author

Philippe Jeammet, Olivier Halfon, Martine Flament, Gwenolé Loas, Maurice Corcos, Paul Bizouard, François Lang, Florence Curt, N. Godart, Jean-Luc Venisse, and F. Perdereau

Subjects
Gynecology, Psychiatry and Mental health, medicine.medical_specialty, Arts and Humanities (miscellaneous), Multicenter study, business.industry, medicine, business
Abstract

Resume L’objectif etait de repondre a la question suivante : existe-il des differences entre les groupes diagnostiques de troubles du comportement alimentaire (TCA) pour la prevalence des troubles depressifs et des troubles anxieux, en tenant compte des differences cliniques observees entre les groupes (âge actuel des sujets, duree d’evolution du TCA, patient hospitalier ou ambulatoire, Body Mass Index) ? Nous avons evalue la frequence des troubles anxieux et des troubles depressifs chez 271 sujets presentant un diagnostic actuel d’anorexie mentale ou de boulimie, en utilisant le Mini International Neuropsychiatric Interview (MINI), version DSM IV. Nous avons compare les prevalences entre les sous-types d’anorexiques (AN-R et AN-BN) et entre les sous-types de boulimiques (BN-P et BN-NP), et enfin entre les anorexiques mentales et les boulimiques en ajustant sur les variables definies ci-dessus. La comorbidite actuelle ou vie entiere des troubles anxieux et depressifs ne differe ni entre les AN-R et les AN-BN, ni entre les BN-P et les BN-NP. Seuls les diagnostics actuels d’agoraphobie et de trouble obsessionnel compulsif sont significativement plus frequents chez les AN que chez les BN. La plus grande frequence de la comorbidite entre trouble obsessionnel compulsif et AN en comparaison avec la BN, connue de longue date, n’est pas remise en question ; la plupart des autres troubles anxieux et des troubles depressifs sont aussi frequents dans tous les types diagnostiques de TCA.

Published
2005
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16. Anxiety disorders in subjects seeking treatment for eating disorders: a DSM-IV controlled study

Author

Nathalie Godart, Olivier Halfon, Jacques Fermanian, Fabienne Perdereau, Paul Bizouard, François Lang, Jean Luc Venisse, Gwenolé Loas, Maurice Corcos, Florence Curt, Philippe Jeammet, and Martine Flament

Subjects
Adult, medicine.medical_specialty, Adolescent, Comorbidity, Anorexia, Anorexia nervosa, Severity of Illness Index, Feeding and Eating Disorders, Prevalence of mental disorders, mental disorders, Prevalence, medicine, Humans, Psychiatry, Biological Psychiatry, Bulimia nervosa, Patient Acceptance of Health Care, medicine.disease, Anxiety Disorders, Diagnostic and Statistical Manual of Mental Disorders, Psychiatry and Mental health, Eating disorders, Anxiety, Female, medicine.symptom, Psychology, Anxiety disorder
Abstract

Women who were referred with an eating disorder (ED) were compared with a matched normal control group to answer the following questions: What are the frequencies of anxiety disorders in cases of anorexia and bulimia nervosa diagnosed according to DSM-IV criteria? Are anxiety disorders significantly more frequent among women with an eating disorder than among women from the community? We assessed the frequencies of six specific anxiety disorders among 271 women with a current diagnosis of anorexia or bulimia nervosa and 271 controls, using the Mini-International Neuropsychiatric Interview, French DSM-IV version. A lifetime comorbidity with at least one anxiety disorder was found in 71% of both the anorexic and the bulimic subjects, significantly higher than the percentage of controls with an anxiety disorder. The prevalence was significantly higher in the eating disorder groups than in controls for most types of anxiety disorder, and between 41.8 and 53.3% of comorbid cases had an anxiety disorder preceding the onset of the eating disorder. Anxiety disorders are significantly more frequent in subjects with eating disorders than in volunteers from the community, a finding that has important etiological and therapeutic implications.

Published
2003
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17. Comparing left and right hand in line bisection at different ages

Author

Florence Curt, Catherine Tzortzis, Maria De Agostini, and Georges Dellatolas

Subjects
Left and right, Neuropsychology and Physiological Psychology, Developmental and Educational Psychology, Young adult, Psychology, Developmental psychology
Abstract

Sixty preschool children (31 boys, 29 girls, 5–6 years old), 60 young adults (30 men, 30 women, 20–45 years old), and 66 older adults (23 men, 43 women, 60–94 years old), bisected 11 lines of diffe...

Published
1999
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18. [Untitled]

Author

Georges Dellatolas, C Dargent-Paré, Florence Curt, and M. De Agostini

Subjects
Longitudinal study, genetic structures, Odds ratio, Child development, eye diseases, Confidence interval, Developmental psychology, Ocular dominance, Genetics, Psychology, Association (psychology), Chi-squared distribution, Genetics (clinical), Ecology, Evolution, Behavior and Systematics, Demography
Abstract

In a sample of 807 normal preschool children aged from 3 to 6, examined eye dominance was not associated with the declared eye dominance of their parents. Forty percent of the children showed left-eyedness. Eyedness was associated with handedness and not significantly related to age group or sex. A strong relationship between the answers of the two parents concerning eye preference was observed. Two hundred forty-four children were followed-up for 2 years. The examinations were carried out once every 6 months. Two thirds of the children showed perfect stability in eye dominance. There was some evidence that stability in eye use tends to increase with age and to be lower in left-handed children with left-handed parents. There is, at present, very little evidence of a positive association between eye dominance in parents and that in their children.

Published
1998
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19. Evolution of Degree and Direction of Hand Preference in Children: Methodological and Theoretical Issues

Author

Pascale Tubert-Bitter, Georges Dellatolas, and Florence Curt

Subjects
Longitudinal study, Neuropsychology and Physiological Psychology, Arts and Humanities (miscellaneous), Hand preference, Rehabilitation, Psychology, Degree (music), Applied Psychology, Developmental psychology
Abstract

This paper presents some methodological and theoretical issues based on a longitudinal study, performed in schools, on hand preference of 256 children, initially aged 3–6 years. Three phenomena are observed: (1) the well-known asymmetry of the hand preference distribution, which probably depends on biological factors; (2) a weak “towards the right” tendency with increasing age, which could be explained by environmental factors; and (3) a strong increase in the degree of hand preference with age which could be a consequence of the subject's own activity. Handedness is considered here as a possibly interesting model to delineate the respective role of biological, environmental, psychological, and pathological factors involved in a simple human behaviour.

Published
1997
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21. Severe anorexia nervosa (AN) during adolescence: 54 months outcome predictive factors

Author

Sylvie Berthoz, Géraldine Dorard, S. Blondin, Florence Curt, Nathalie Godart, Laboratoire de Psychopathologie et Processus de Santé (LPPS (URP_4057)), Université Paris Cité (UPCité), Techniques et enjeux du corps (TEC - EA 3625), Université Paris Descartes - Paris 5 (UPD5), Institut Mutualiste de Montsouris (IMM), Troubles du comportement alimentaire de l'adolescent (UMR_S 669), Université Paris-Sud - Paris 11 (UP11)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), and Université Paris Descartes - Faculté de Médecine (UPD5 Médecine)

Subjects
Psychiatry and Mental health, Pediatrics, medicine.medical_specialty, Anorexia nervosa (differential diagnoses), business.industry, Pediatrics, Perinatology and Child Health, Developmental and Educational Psychology, medicine, business, Outcome (game theory), [SHS]Humanities and Social Sciences
Abstract

International audience; Objective.– We investigated the course and pronostic factors of AN over 54 months of patients with a teenage-onset of the disease.Method.– Sixty females, with an onset age of DSM-IV AN before 19 years were included in this Randomized Control Trial. Data were collected for 59 patients at the 54-months follow-up evaluation. The Main Outcome Measure was the Morgan and Russell outcome category at 54-months of follow-up. Secondary outcomes index included the Global Outcome Assessment Scale and AN symptoms or their consequences (eating symptoms, body mass index, amenorrhea, number of hospitalizations in the course of follow-up). Predictive factors described in the literature were considered.Results.– TAU + FT participants achieved a Good or Intermediate outcome (Morgan and Russell categories) about twice as often as those of the TAU group. The impact of predictive factors will be exposed and discussed in details.

Published
2012
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22. A Randomized Controlled Trial of Adjunctive Family Therapy and Treatment as Usual Following Inpatient Treatment for Anorexia Nervosa Adolescents

Author

Réjane Lucet, Maurice Corcos, Sylvie Berthoz, Nathalie Godart, Bruno Falissard, Florence Curt, Frederic Atger, Anne-Sophie Horreard, Martine F. Flament, Jacques Fermanian, Jenny Wallier, Zoé Rein, Philippe Jeammet, Ivan Eisler, Irène Kaganski, and Fabienne Perdereau

Subjects
Family therapy, Adult, Pediatrics, medicine.medical_specialty, Anorexia Nervosa, Non-Clinical Medicine, Adolescent, Clinical Research Design, MEDLINE, lcsh:Medicine, Treatment as usual, Social and Behavioral Sciences, law.invention, Young Adult, Randomized controlled trial, Sociology, law, Outpatients, medicine, Combined Modality Therapy, Psychology, Humans, Young adult, lcsh:Science, Psychiatry, Inpatients, Multidisciplinary, Health Care Policy, business.industry, lcsh:R, Continuity of Patient Care, medicine.disease, Eating disorders, Mental Health, Treatment Outcome, Anorexia nervosa (differential diagnoses), Therapies, Medicine, lcsh:Q, Family Therapy, Female, business, Social Adjustment, Algorithms, Research Article, Follow-Up Studies
Abstract

UNLABELLED: Research on treatments in anorexia nervosa (AN) is scarce. Although most of the therapeutic programs used in 'real world practice' in AN treatment resort to multidisciplinary approaches, they have rarely been evaluated. OBJECTIVE: To compare two multidimensional post-hospitalization outpatients treatment programs for adolescents with severe AN: Treatment as Usual (TAU) versus this treatment plus family therapy (TAU+FT). METHOD: Sixty female AN adolescents, aged 13 to 19 years, were included in a randomized parallel controlled trial conducted from 1999 to 2002 for the recruitment, and until 2004 for the 18 months follow-up. Allocation to one of the two treatment groups (30 in each arm) was randomised. The TAU program included sessions for the patient alone as well as sessions with a psychiatrist for the patient and her parents. The TAU+FT program was identical to the usual one but also included family therapy sessions targeting intra-familial dynamics, but not eating disorder symptoms. The main Outcome Measure was the Morgan and Russell outcome category (Good or Intermediate versus Poor outcome). Secondary outcome indicators included AN symptoms or their consequences (eating symptoms, body mass index, amenorrhea, number of hospitalizations in the course of follow-up, social adjustment). The evaluators, but not participants, were blind to randomization. RESULTS: At 18 months follow-up, we found a significant group effect for the Morgan and Russell outcome category in favor of the program with family therapy (Intention-to-treat: TAU+FT :12/30 (40%); TAU : 5/29 (17.2%) p = 0.05; Per Protocol analysis: respectively 12/26 (46.2%); 4/27 (14.8%), p = 0.01). Similar group effects were observed in terms of achievement of a healthy weight (i.e., BMI≥10(th) percentile) and menstrual status. CONCLUSIONS: Adding family therapy sessions, focusing on intra-familial dynamics rather than eating symptomatology, to a multidimensional program improves treatment effectiveness in girls with severe AN. TRIAL REGISTRATION: Controlled-trials.com ISRCTN71142875.

Published
2012

23. Drop-out from adolescent and young adult inpatient treatment for anorexia nervosa

Author

Bruno Falissard, Caroline Huas, Alexandre Apfel, Florence Curt, Philippe Pioggiosi, Nathalie Godart, Tamara Hubert, Jenny Wallier, and Anne-Solène Maria

Subjects
Male, Pediatrics, medicine.medical_specialty, Multivariate analysis, Anorexia Nervosa, Patient Dropouts, Adolescent, Impulsivity, Motivational interventions, Young Adult, Predictive Value of Tests, Drop out, Surveys and Questionnaires, Medicine, Humans, Prospective Studies, Big Five personality traits, Young adult, Psychiatry, Prospective cohort study, Biological Psychiatry, Analysis of Variance, business.industry, Hospitalization, Psychiatry and Mental health, Logistic Models, Anorexia nervosa (differential diagnoses), Female, medicine.symptom, business
Abstract

We examined factors predictive of dropout from inpatient treatment for anorexia nervosa (AN) among adolescents in a prospective study of 359 consecutive hospitalizations for AN (DSM-IV). Patients were assessed at admission (clinical, socio-demographic, and psychological data). Multivariate analyses were performed. Drop-out (i.e. leaving hospital before the target weight is achieved) occurred in 24% (n=86) of hospitalizations; in 42.3% (n=30) of the cases, dropout was initiated by the treatment team and in 58.6% (n=41) by the patients and/or their parents. 18.6% (16/86) occurred during the first half of the inpatient program. Frequency of drop-out was significantly higher when the patient was living with only one parent, had been hospitalized previously, had a lower BMI at admission and was over 18 at admission. These elements should draw the attention of the clinician, so that he/she can prepare hospitalization with patients presenting lower admission BMI, particularly by motivational interventions for a better therapeutic alliance, and by the deployment of intensive accompaniment of single parents. Further studies aiming to replicate these results, and including the evaluation of other clinical dimensions such as impulsivity and other personality traits, are needed to elucidate this important topic.

Published
2011

24. Decreased sensitivity to facial emotions in adolescents with Borderline Personality Disorder

Author

Alexandra Pham-Scottez, David Sapinho, Florence Curt, Marion Robin, Mario Speranza, Maurice Corcos, Sylvie Berthoz, Corinne Dugré-Le Bigre, and Gayannée Kedia

Subjects
Adolescent, media_common.quotation_subject, Emotions, Anger, behavioral disciplines and activities, Developmental psychology, Interpersonal relationship, Young Adult, Borderline Personality Disorder, mental disorders, medicine, Humans, Emotional expression, Interpersonal Relations, Young adult, Borderline personality disorder, Biological Psychiatry, media_common, Facial expression, Social perception, Recognition, Psychology, medicine.disease, Facial Expression, Psychiatry and Mental health, Social Perception, Happiness, Female, Psychology
Abstract

Whereas severe relationship dysfunction in BPD is well described in adolescence, little is known about the way these patients process facial expressions of emotion. Because few data are available regarding this issue, the present study compared the sensitivity to morphed facial emotional expressions of 22 BPD female adolescents versus 22 matched controls. Participants had to identify as rapidly as possible the various emotions displayed progressively and continuously on faces. Results indicate that adolescents with BPD are less sensitive to facial expressions of anger and happiness, i.e. they require more intense facial expressions than control participants to correctly identify these two emotions. However, they did not exhibit any deficit in recognizing fully expressed emotions. These results suggest that sensitivity to facial emotions is impaired in adolescents with BPD. Theoretical and clinical implications are discussed.

Published
2011

25. Bonding and expressed emotion: two interlinked concepts?

Author

Anne-Solène Maria, Nathalie Godart, Jeanne Duclos, Sarah Vibert, Alexandre Apfel, Fabienne Perdereau, Florence Curt, Géraldine Dorard, and Zoé Rein

Subjects
Adult, Male, Anorexia Nervosa, Psychometrics, Adolescent, Social environment, Mothers, Object Attachment, Social relation, Developmental psychology, Psychiatry and Mental health, Clinical Psychology, Expressed Emotion, Fathers, Young Adult, Anorexia nervosa (differential diagnoses), Personal Autonomy, Expressed emotion, Humans, Emotional expression, Family, Female, Family Relations, Psychology
Abstract

Background: Bonding and expressed emotion (EE) are two concepts modeling family relationships. Two studies, with contradictory results, have explored whether these concepts and their corresponding instruments [the Parental Bonding Instrument (PBI) and the Camberwell Family Interview] do indeed measure the same aspects of family relationships. Our first objective was to compare the adolescents' perceptions of family relationships using the PBI, and the parental viewpoint using the Five-Minute Speech Sample (FMSS-EE). Secondly, we compared the PBI scores and EE levels of the parents. Sampling and Methods: Sixty adolescent girls with anorexia nervosa completed the PBI. The FMSS and a modified version of the PBI were administered to parents separately. Results: No significant link was identified between adolescent PBI scores and parental EE levels. However, a link between maternal ‘modified' PBI scores and maternal EE was observed: when mothers registered a high Final EE, they were more likely to deny their daughter's psychological autonomy compared to mothers with lower EE. Conclusions: Our empirical results do not support the hypothesis of an overlap between the two concepts. Indeed bonding and EE measure the same object, i.e. the quality of family relationships, but time scales differ and so do the perspectives (patient vs. parental viewpoint).

Published
2011

26. Apport du Multimorph à l'étude des processus de Reconnaissance Émotionnelle Faciale (REF). Exemple de la personnalité borderline à l'adolescence

Author

Mario Speranza, C. Dugre-Le Bigre, D. Sapinho, Sylvie Berthoz, Maurice Corcos, Alexandra Pham-Scottez, Florence Curt, Marion Robin, Gayannée Kedia, Institut Mutualiste de Montsouris (IMM), Troubles du comportement alimentaire de l'adolescent (UMR_S 669), Université Paris-Sud - Paris 11 (UP11)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Techniques et enjeux du corps (TEC - EA 3625), Université Paris Descartes - Paris 5 (UPD5), University of Cologne, Hôpital Mignot, Hôpital Sainte-Anne, Institut Mutualiste de Montsouris ( IMM ), Troubles du comportement alimentaire de l'adolescent ( UMR_S 669 ), Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Université Paris-Sud - Paris 11 ( UP11 ), Techniques et enjeux du corps ( TEC - EA 3625 ), Université Paris Descartes - Paris 5 ( UPD5 ), and Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Sud - Paris 11 (UP11)

Subjects
[SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior, Reconnaissance Émotionnelle Faciale, 05 social sciences, Personnalité Borderline, 050105 experimental psychology, 030227 psychiatry, Adolescence, [ SDV.NEU.PC ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior, 03 medical and health sciences, Psychiatry and Mental health, 0302 clinical medicine, Arts and Humanities (miscellaneous), Multimorph, Borderline Personality Disorder, 0501 psychology and cognitive sciences, Facial Emotion Recognition, Applied Psychology
Abstract

International audience; Cet article expose l'intérêt du Multimorph, outil expérimental évaluant les performances de traitement dynamique de visages émotionnels par le morphing. La version présentée ici permet de voir évoluer lentement et continuellement un visage de la neutralité à l'une des six émotions de base pleinement exprimée (colère, dégoût, joie, peur, surprise et tristesse). L'intérêt du Multimorph est analysé à partir d'une revue des études utilisant ce paradigme dans la mesure des capacités de reconnaissance émotionnelle faciale. L'exemple de la personnalité borderline à l'adolescence est développé, afin d'en analyser les corrélats clinico-expérimentaux. Les limites et les perspectives du Multimorph sont ensuite discutées.

Published
2011
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27. Expressed emotion measure adaptation into a foreign language

Author

Alexandre Apfel, Bruno Falissard, A. Verdier, Fabienne Perdereau, Zoé Rein, Jenny Wallier, Jacques Fermanian, Jeanne Duclos, Florence Curt, N. Godart, and S. Zaden

Subjects
Adult, Male, Measure (data warehouse), Foreign language, Reproducibility of Results, Adaptation (eye), Sample (statistics), medicine.disease, Sampling Studies, Psychiatry and Mental health, Clinical Psychology, Eating disorders, Inter-rater reliability, Expressed Emotion, Statistics, Adaptation, Psychological, medicine, Expressed emotion, Humans, Speech, Female, Psychology, Association (psychology), Social psychology, Language
Abstract

Expressed emotion (EE) measures have been created in English; adaptation into a foreign language is difficult. The aim of this study was to adapt the five minutes speech sample (FMSS), with a designed procedure ensuring optimum quality of the adaptation, and thus better trans-cultural validity. A strategy for improving inter-rater agreement comprised three phases: (1) phase of initial ratings (70 French samples), (2) experimental phase in two steps: ratings of 40 other samples in French, followed by analysis of differences between the French-language ratings and English-language ratings and (3) final rating phase of the initial 70 samples. For each phase, the κ coefficients measuring inter-rater agreement were calculated and compared using a bootstrap procedure. The improvements between these scorings were significant at p

Published
2010

28. Distributions of hand preference and hand skill asymmetry in preschool children: Theoretical implications

Author

Georges Dellatolas, Jean Maccario, and Florence Curt

Subjects
Male, Age effect, Genotype, Hand preference, Cognitive Neuroscience, media_common.quotation_subject, education, Normal component, Experimental and Cognitive Psychology, behavioral disciplines and activities, Asymmetry, Functional Laterality, Task (project management), Developmental psychology, Behavioral Neuroscience, Child Development, Humans, Child, Right shift, media_common, Preschool child, Models, Genetic, Test (assessment), Motor Skills, Child, Preschool, Female, Psychology, psychological phenomena and processes
Abstract

We describe the distributions of hand skill asymmetry for the Peg-moving task and the Graphic test among 765 preschool children. A single normal component was observed for the Peg-moving task, but two normal components for the Graphic test, which corresponded primarily to the right- and left-handed children. Hand Preference and Graphic test hand skill asymmetry were age-dependent, but there was no age effect on the PMT hand skill asymmetry. Results are discussed in relation to the Annett's Right Shift theory.

Published
1992
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29. Birth Order and Month of Birth Are Not Related with Handedness in a Sample of 9370 Young Men

Author

Joseph Lellouch, Florence Curt, and Georges Dellatolas

Subjects
Adult, Male, Neurologic Examination, Adolescent, Month of birth, Season of birth, Cognitive Neuroscience, Experimental and Cognitive Psychology, Sample (statistics), Functional Laterality, Developmental psychology, Birth order, Military Personnel, Neuropsychology and Physiological Psychology, Humans, France, Seasons, Birth Order, Psychology, Psychomotor Performance
Abstract

In a large representative sample of young men, no clearly significant relationship between handedness and birth order or season of birth was found; the trend was opposite to that claimed by Bakan (1971) and Badian (1983) .

Published
1991
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30. Predictive factors of length of inpatient treatment in anorexia nervosa

Author

Fabienne Perdereau, Zoé Rein, Nathalie Godart, Luisa Strik Lievers, Florence Curt, P. Jeammet, Jenny Wallier, Dept. of Psychiatry for Adolescents and Young Adults, Faculté de Médecine, Site Institut Mutualiste Montsouris, Université Paris Descartes - Paris 5 ( UPD5 ), Troubles du comportement alimentaire de l'adolescent ( UMR_S 669 ), Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Université Paris-Sud - Paris 11 ( UP11 ), Université Paris-Sud - Paris 11 ( UP11 ), Institute of Psychiatry, Kings College, Institut Mutualiste de Montsouris ( IMM ), Université Paris Descartes - Paris 5 (UPD5), Troubles du comportement alimentaire de l'adolescent (UMR_S 669), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Sud - Paris 11 (UP11), Université Paris-Sud - Paris 11 (UP11), and Institut Mutualiste de Montsouris (IMM)

Subjects
050103 clinical psychology, Time Factors, Severity of Illness Index, anorexia nervosa, Body Mass Index, 0302 clinical medicine, ddc:150, Professional-Family Relations, inpatient treatment, Developmental and Educational Psychology, Child and adolescent psychiatry, Psychology, Medicine, Social Medicine, ComputingMilieux_MISCELLANEOUS, Psychological Disorders, Mental Health Treatment and Prevention, 05 social sciences, Professional-Patient Relations, General Medicine, Prognosis, 3. Good health, Psychiatry and Mental health, Treatment Outcome, psychische Störungen, Behandlung und Prävention, Anorexia nervosa (differential diagnoses), Medicine and health, Female, France, medicine.medical_specialty, Clinical variables, Adolescent, length of stay, Young Adult, 03 medical and health sciences, medicine, Humans, 0501 psychology and cognitive sciences, ddc:610, Psychiatry, Medizin und Gesundheit, Body Weight, 030227 psychiatry, Medizin, Sozialmedizin, Psychologie, Pediatrics, Perinatology and Child Health, Emergency medicine, Linear Models, Patient Compliance, Patient Participation
Abstract

Objective: To identify clinical variables influencing the length of stay (LOS) of inpatient treatment for anorexia nervosa (AN). Method: We analyzed structured clinical charts of 300 consecutive hospitalizations for AN in a specialized eating disorder unit. The sample included patients from 12 to 22 years old. Factors related to the patient and events occurring during the stay were investigated as possible predictors of LOS. Results: Mean LOS was 135 days. The best model of linear regression revealed that the following factors were significantly related to LOS: duration of AN at admission, use of tube feeding during the stay, accomplishment of the therapeutic weight contract and presence of a comorbid disorder. Conclusions: The identification of factors influencing duration of stay, both at the outset and during the hospitalization, could help clinicians to optimize and individualize treatments, as well as increase patient and family compliance.

Published
2008
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31. Decreased immune response in alexithymic women: a cross-sectional study

Author

Sylvie Berthoz, Claire Perrin, Catherine Touitou, Gérard Chaouat, Maurice Corcos, Florence Curt, Corinne Dugré-Le Bigre, Olivier Guilbaud, Philippe Jeammet, Jenny Wallier, and Martine Strebler

Subjects
Adult, medicine.medical_specialty, Adolescent, Hydrocortisone, Cross-sectional study, CD4-CD8 Ratio, Anxiety, Lymphocyte Activation, Severity of Illness Index, Toronto Alexithymia Scale, Young Adult, Immune system, Alexithymia, T-Lymphocyte Subsets, Internal medicine, Medicine, Humans, Affective Symptoms, Lymphocyte Count, Phytohemagglutinins, Cells, Cultured, Phytohaemagglutinin, Pharmacology, Immunity, Cellular, medicine.diagnostic_test, biology, business.industry, Depression, Interleukins, Smoking, Interleukin, General Medicine, medicine.disease, Expressed Emotion, Cross-Sectional Studies, Socioeconomic Factors, Immunology, biology.protein, Cytokines, Female, medicine.symptom, business, Psychoneuroimmunology
Abstract

It has been reported in a few studies that alexithymia is associated with impaired immune response but results are still contradictory. The present study investigates whether alexithymia is associated with lower cell-mediated (Th-1) immune response. Fifty-one healthy 18–27-year-old women were selected from healthy subjects on the basis of high or low cut-off scores on the 20-item Toronto Alexithymia Scale (TAS-20). They were evaluated using standardized psychiatric rating scales notably the Hospital Anxiety Depressive Scale (HAD) and the Mini Neuropsychiatric Interview (MINI). None of the subjects were suffering from psychiatric disorders. Twenty-seven were classified as alexithymics and 24 as non-alexithymics according to the TAS-20. Blood was drawn for lymphocyte subset counts (CD4, CD8), in vitro production of interleukin 1 (IL-1β), IL-2, IL-4, and IL-10 by phytohaemagglutinin stimulated peripheral lymphocytes, and cortisol. Women with alexithymia exhibited decreased interleukin 1β, IL-2 and IL-4 production with reduced ratios of Th1/Th2 (IL-2/IL-10) and of CD4/CD8, as well as reduced CD4 percentages. IL-2 and IL-4 production remained significantly diminished in the alexithymic group, even after adjusting for between-group differences in anxiety and depression levels on the HAD. This study further demonstrates that alexithymic women have altered immune function, with a predominance of depressed cell-mediated immunity and a skewed Th1/Th2 ratio towards Th2 response.

Published
2008

32. Resolving a disagreement in a clinical team: overcoming conflicting views about the role of family therapy in an outpatient treatment programme for anorexia nervosa

Author

R. Lucet, Nathalie Godart, Martine F. Flament, Florence Curt, Maurice Corcos, P. Jeammet, Irène Kaganski, F. Perdereau, Zoé Rein, and Jacques Fermanian

Subjects
Family therapy, Clinical team, Counseling, medicine.medical_specialty, Psychotherapist, Anorexia Nervosa, Adolescent, Therapeutic treatment, Anorexia nervosa, Outcome (game theory), Ambulatory Care, Medicine, Humans, Set (psychology), Patient Care Team, business.industry, medicine.disease, Combined Modality Therapy, Dissent and Disputes, Psychiatry and Mental health, Clinical Psychology, Adolescent psychiatry, Family medicine, Family Therapy, business, Follow-Up Studies
Abstract

In the Adolescent Psychiatry Department at the Institut Mutualiste Montsouris, Paris, as is also observed in the literature, the outcome for anorexic patients can sometimes be catastrophic, regardless of treatments proposed. This disturbing finding led us to reassess our therapeutic treatment strategies, in an effort to improve patient outcome. The multidimensional treatment program implemented in the Department includes parent counselling, but not the whole family in a family therapy procedure. It has been demonstrated better outcome for patients who underwent family therapy in comparison to patients who underwent individual therapy. This raised the question of whether family therapy could improve our outpatient programme. This paper describes here how a research programme was developed to resolve a disagreement in our clinical team as to whether family therapy should be added to the existing care programme. The paper describes the difficulties encountered by our team, and the experimental design chosen to resolve the debate. Data will not be set out here.

Published
2007

33. Does the frequency of anxiety and depressive disorders differ between diagnostic subtypes of anorexia nervosa and bulimia?

Author

Fabienne Perdereau, Gwenolé Loas, Sylvie Berthoz, Martine F. Flament, Olivier Halfon, Pierre Bizouard, François Lang, Florence Curt, Nathalie Godart, Zoé Rein, Maurice Corcos, Jean-Luc Venisse, and Philippe Jeammet

Subjects
Adult, medicine.medical_specialty, Anorexia Nervosa, Adolescent, Anorexia nervosa, Severity of Illness Index, medicine, Prevalence, Humans, Psychiatry, Bulimia Nervosa, Mini-international neuropsychiatric interview, Depressive Disorder, Panic disorder, Panic, medicine.disease, Comorbidity, Anxiety Disorders, Psychiatry and Mental health, Eating disorders, Anxiety, Female, medicine.symptom, Psychology, Anxiety disorder, Clinical psychology
Abstract

Objective: The objective of the present work is to determine whether the prevalence of depressive and anxiety disorders varies in subgroups of eating disorders (ED) according to age, ED duration, mode of care provision, and body mass index (BMI). Method: Using the Mini International Neuropsychiatric Interview (MINI), the frequency of anxiety and depressive disorders was evaluated in 271 ED participants. Their prevalence was compared in subgroups of anorexics (AN-R and AN-BN) and bulimics (BN), both before and after controlling for potential confounding variables. Results: Current or lifetime comorbidity of anxiety and depressive disorders did not differ between AN-R and AN-BN groups. Social phobia, panic disorders, and obsessive-compulsive disorder (OCD) were significantly more frequent in AN-BN and AN-R groups. Panic disorder was more frequent in the BN group. Conclusion: Several confounding factors, in particular those identified in the present study, may explain previous conflicting results on the frequency of anxiety and depressive disorders in ED. Nevertheless, the study confirmed that OCD is more frequent in AN, even after controlling for confounding factors. © 2006 by Wiley Periodicals, Inc. Int J Eat Disord 2006; 39:772–778

Published
2006

34. Expressed emotion and anorexia nervosa: the validation of the Five-Minute Speech Sample in reference to the Camberwell Family Interview

Author

Nathalie Godart, Florence Curt, Fabienne Perdereau, Zoé Rein, Philippe Jeammet, and Jacques Fermanian

Subjects
Observer Variation, Anorexia Nervosa, Adolescent, Hospitalized patients, Verbal Behavior, Sample (statistics), Middle Aged, Anorexia nervosa, medicine.disease, Camberwell family interview, Developmental psychology, Psychiatry and Mental health, Expressed Emotion, Sample size determination, Surveys and Questionnaires, Interview, Psychological, medicine, Expressed emotion, Humans, Speech, Family, Female, Psychology, Clinical psychology
Abstract

Objective: The goal of the current study was to test whether the Five-Minute Speech Sample (FMSS) assessments of expressed emotion (EE) in families with a daughter with anorexia nervosa (AN) are valid in comparison to the Camberwell Family Interview (CFI). Method: The sample included parents of hospitalized patients with AN. Assessments were conducted at the time of patients' discharge from the hospital. The participants (n = 40) were assessed individually with the FMSS and then the CFI. FMSS-EE ratings were classified as high or low for Emotional Overinvolvement (EOI), Critical EE, and Final EE (overall rating). For the CFI, average EE scores were computed on the same subscales. Results: Comparisons of FMSS subgroups on the CFI mean scores revealed that parents rated high EE on the FMSS subscales (EOI and Final EE) had significantly greater mean scores on the CFI than parents rated low EE on the FMSS (EOI: p = .02; Final EE: p = .04). Furthermore, FMSS-EE ratings were positively correlated to CFI-EE ratings for EOI EE (r = .38, p = .01), Critical EE (r = .31, p = .05), and Final EE (r = .29, p = .07). Conclusion: The FMSS can reliably measure EE in reference to the CFI in terms of Final EE and EOI EE. For the Critical EE subgroup, further investigation is needed with a bigger sample size. © 2006 Wiley Periodicals, Inc., Int J Eat Disord, 2006

Published
2006

35. Predictive factors of social disability in anorexic and bulimic patients

Author

Nathalie Godart, Maurice Corcos, Martine Flament, Fabienne Perdereau, Florence Curt, Ph Jeammet, Gwenolé Loas, Olivier Halfon, François Lang, Jean-Luc Venisse, and Paul Bizouard

Subjects
Adult, medicine.medical_specialty, Anorexia Nervosa, Adolescent, Comorbidity, Risk Factors, medicine, Humans, Bulimia, Psychiatry, Depression (differential diagnoses), Social functioning, Mini-international neuropsychiatric interview, Analysis of Variance, Depressive Disorder, Bulimia nervosa, medicine.disease, Anxiety Disorders, Social disability, Psychiatry and Mental health, Clinical Psychology, Eating disorders, Logistic Models, Anorexia nervosa (differential diagnoses), Case-Control Studies, Anxiety, Female, France, medicine.symptom, Psychology, Social Adjustment, Clinical psychology
Abstract

Objectives: The purpose of this study was to determine whether subjects suffering from anorexia nervosa (AN) or bulimia nervosa (BN) would demonstrate more severe social disability than a control group; and whether social disability could be best explained as a function of the eating disorder itself or as a function of comorbid anxiety or depressive disorders. Method: Subjects were166 AN subjects, 105 BN subjects and 271 control subjects matched for age, sex and socio-economic status. Prevalence of anxiety or depressive disorders was assessed (through the Mini International Neuropsychiatric Interview), and social functioning was measured (through the Groningen scale). Results: The majority of AN and BN subjects demonstrated social disability in the “social role” (leisure time, time spent with friends) and the “occupational role” (work or educational activities). A regression analysis was employed to uncover predictive factors of social disability. Eating disorders (AN and BN), anxiety disorders and depression accounted for a large portion of social disability. Discussion: Anxiety and depressive disorders appear to play an important role in the type of social disability demonstrated in eating disorder patients. Therapeutic implications are discussed.

Published
2005

36. Role of gender and hormone-related events on IgE, atopy, and eosinophils in the Epidemiological Study on the Genetics and Environment of Asthma, bronchial hyperresponsiveness and atopy

Author

Valérie Siroux, Marie-Pierre Oryszczyn, Jean Maccario, Francine Kauffmann, Florence Curt, Epidémiologie et Biostatistique, Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Département de médecine aiguë spécialisée, CHU Grenoble-Hôpital Michallon, and Kaniewski, Nadine

Subjects
Hypersensitivity, Immediate, Male, Allergy, MESH: Leukocyte, MESH: Asthma, Immunoglobulin E, Severity of Illness Index, Atopy, Leukocyte Count, MESH: Hormones, immune system diseases, MESH: Child, Immunology and Allergy, Medicine, Eosinophilia, Age of Onset, Child, Genetics, MESH: Epidemiologic Studies, biology, MESH: Immunoglobulin E, MESH: Case-Control Studies, medicine.anatomical_structure, Bronchial hyperresponsiveness, Child, Preschool, [SDV.IMM]Life Sciences [q-bio]/Immunology, Female, medicine.symptom, MESH: Hypersensitivity, Immediate, Bronchial Hyperreactivity, Menopause, MESH: Contraceptives, Oral, Adult, [SDV.IMM] Life Sciences [q-bio]/Immunology, Adolescent, MESH: Age of Onset, Immunology, Sex Factors, MESH: Eosinophils, Humans, Asthma, MESH: Adolescent, Menarche, MESH: Humans, business.industry, MESH: Child, Preschool, MESH: Bronchial Hyperreactivity, MESH: Adult, Eosinophil, medicine.disease, Hormones, respiratory tract diseases, Eosinophils, Epidemiologic Studies, [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, Case-Control Studies, biology.protein, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Age of onset, business, MESH: Female, Contraceptives, Oral
Abstract

Background The pattern of asthma over the lifespan is different in male and female patients, but etiologic differences according to gender are only partially understood. In women, information regarding factors explaining perimenstrual asthma and the role of hormone-related aspects on asthma-related phenotypes is scanty. Objective To assess the relationships of eosinophils, IgE, and atopy with (1) asthma according to gender and age of onset and (2) hormone-related events. Methods Using data from the Epidemiological study on the Genetics and Environment of Asthma, Bronchial Hyperresponsiveness and Atopy, adults and children with asthma recruited in chest clinics (n=313) and first-degree relatives of patients with asthma (n=214) were compared with nonasthmatic controls (n=334) and first-degree relatives without asthma (n=595). Results Among asthmatic women, eosinophilia was significantly associated with perimenstrual asthma independently from age, smoking, and asthma severity (eosinophils/mm 3 330 vs 194; P =.01). In nonasthmatic women, IgE level was significantly decreased (by half) and atopy decreased with menopause, and IgE increased with oral contraceptive use, independently from age and smoking. Considering both genders, the increase of eosinophil counts with asthma was significantly greater in women with childhood-onset asthma than in women with adulthood-onset or in men in general. No interaction between gender and asthma was observed for eosinophils in children and for IgE level and atopy in children and adults. Conclusion Results suggest a role of hormone-related events on asthma-related traits and support the hypothesis of the role of eosinophils in the persistence and severity of asthma.

Published
2004
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37. Poster

Author

Olivera Aleksic, Milica Pejovic-Milovancevic, Smiljka Popovic-Deusic, Biljana Pirgic, Ivana Sojic, Christoph Correll, Umesh Parikh, Vladimir Olshanskiy, Bhrigu Chopra, John M. Kane, Anil K. Malhotra, Sonja Sieslack, Gottfried Maria Barth, Gunther Klosinski, Sheila Sadigorsky, Sefi Kronenberg, Amos Frisch, Nicola Williams, Bruce Tonge, Neville King, Glenn Melvin, Amanda Dudley, Michael Gordon, Ester Klimkeit, Simon Hatch, John Breddy, Heleen DeCory, Sara Cameron, Mary Solanto, Maria Serra-Pinheiro, Isabella Sousa, Paulo Mattos, Fernanda Gomes, Giuseppe Pastura, Desna Milinkovic, Oliver Bilke, Sibille Kühnel, Bernhard Winterfeld, John Campo, James Perel, David Axelson, Jeff Bridge, Boris Birmaher, Neal Ryan, David Brent, Edmund J. S. Sonuga-Barke, Dorothea Y. Sanchez, Mani Pavuluri, David B. Henry, Julie A. Carbray, Gwendolyn Sampson, Michael W. Naylor, Philip G. Janicak, Stefan Gebhardt, Frank Theisen, Michael Haberhausen, Monika Heinzel-Gutenbrunner, Peter Wehmeier, Jürgen-Christian Krieg, Wolfgang Kühnau, Jörg Schmidtke, Helmut Remschmidt, Johannes Hebebrand, Hans-Willi Clement, Christian Fleischhaker, Klaus Hennighausen, Eberhard Schulz, Reiner Frank, Belda Karamete, Gunnel Löndahl, Peik Gustafsson, Anneli Parnegdrd, Giancarlo Rigon, Simona Chiodo, Alessandra Mancaruso, Daniele Giovanni Poggioli, Stefano Costa, Pedro Pires, Isabel Brito, Isabel Carvalho, Sara Almeida, Paula Zaragoza, Yury Shevchenko, Vasilisa Korneeva, Miodrag Stankovic, Aneta Lakic, Vesna Milovanovic, Sandra Stankovic, Bernard Hobrücker, Filip Caby, Jean Chambry, Stéphane Laudrin, Catherine Graindorge, Arata Oiji, Yukiko Morioka, Ami Murata, Madoka Sato, Yume Hashizume, Katarina Müller, Willigis Werner, Matthias Martin, Eva Mattejat, Myriam Olivieri, Annalisa Simoncini, Sonia Marchegiani, Marco Lazzorotto Muratori, Gabriele Borsetti, Shewikar Farrag, Riccardo Coltrinari, Doa Habib, Daniel Fung, Nelson Lee, Susanne Ohmann, C. Popow, M. Lanzenberger, H. Herzog, S. Schuch, S. Miksch, Fatemeh Abdollahy, S. Khani, B. Shabankhani, Joao Guerra, Claudia Fontes, Vania Martins, Ana Teles, Corina Rodrigues, Zulmira Correia, Gereon Becht-Jördens, Catherine McElearney, Michael Fitzgerald Henry Marsh, Alexander Naumann, Dirk Holst, Annette Engbarth, Tiberiu Mircea, Ashima Nehra, Savita Malhotra, Subho Chakrabarti, Shashi Kiran, Srinath Shoba, Allan Hvolby, Jan Ib Jorgensen, Marco Medeiros, Ariete Correia, Maria Gabilondo, Pedro Caldeira da Silva, Augusto Carreira, Jae-Won Yang, Yeoung-Rang Kim, Sung-Do David Hong, Sang-Sin Lee, Seong-Hu Lim, Jeoung-Hwan Park, Vera Trbic, Danica Boskovic, Jan Pauschardt, Fritz Mattejat, Kurt Quaschner, Erika Lischka, Mechthild Bauer, Franka Petzke, Britta Wehrmann, Sigita Lesinskiene, Laura Paskauskaite, Luisa Garcia-Giralda Bueno, Juana Montiel Gonzales, Javier Gallego Cumbres, Francisco Gutierrez Asensio, Susanne Denoix, Franz Kimmig, Marc Weinhardt, Peter Greven, Stefan Buchmann, Nurgül Atas, Ute Jonkanski, Bodo Pisarsky, Silvia Treuter, Josep Cornellà, Alex Llusent, Lara Condesso, António Trigueiros, Klaus Schütz, Michael Tarren-Sweeney, Philip Hazell, Luigi Mazzone, Diego Mugno, Liliana Ruta, Valentina Genitori D’Arrigo, Perrotta Concetta Simona, Teresa Mattina, Domenico Mazzone, Ralf Nordbeck, Wolfgang Gierow, Frank Haessler, Johannes Buchmann, Lucia Bliznakova, Yvonne Grimmer, H. J. Roth, Christine Jennen-Steinmetz, Martin H. Schmidt, Katja Becker, Andrea G. Ludolph, Alexander Storch, Tobias Boeckers, Joachim Kirsch, Jörg M. Fegert, Oksana Drevitska, Carlo Cianchetti, Simona Corona, Maria Foscoliano, Daniela Contu, Giuseppina Sannio Fancello, Anna Costa, Mara Roello, Angela Romano, Anna Fabrizi, Andrea Pelliccia, Maria Matricardi, Nickola Matthias, Timo Lesnick, Matthias Gass, Linyan Su, Jishui Zhang, Dazing Wu, Xuerong Luo, Ignazio Ardizzone, Paola D’Oto, Francesca Priskich, Elvira Rigillo, Nadia Tomassetti, Francesca Vagnoni, Beate Sabisch, Anja Hahne, Lisa Glass, Angela D. Friederici, Waldemar von Suchodoletz, Carlo Di Brina, Andrea Pagnacco, Flavia Capozzi, Roberta Penge, Fabio Bocci, Laura Cantonetti, Alessandra De Carlo, Barbara Scanferla, Teresa Sebastiani, Cristina Vagnoni, Xueping Gao, Yasong Du, Fabio Lorenzetti, Michael von Aster, Martin Schweiter, Karin Kucian, Thomas Loenneker, Thomas Dietrich, Ernst Martin-Fiori, Hesham Abuhegaz, Hashem Bahary, Dae-Hwan Lee, Bong-Seog Kim, Seong-Ill Jeon, Sun-Lu Chung, Maria Conceicao Taborda da Simoes, Maria Luz Vale da Dias, Ulf Engqvist, Per-Anders Rydelius, Maria Dores das Formosinho, Ana Monica Pinto, Luiza Nobre Lima, Tobias Edbom, Jan-Olov Larsson, Paul Lichtenstein, Bernardo Perez, Macarena Marin, Su-Jin Yang, Helen Lee, Kyung-Sun Noh, Ferdinand Keller, Lutz Goldbeck, Ghizlane Benjelloun, Dirk Dhossche, Sara Stanfill, Akiko Takahara, Minemitsu Kusu, Sumiko Watanabe, Tatsuya Matsui, Kengo Ikeda, Hiroe Matsuda, Hiie Allik, Hans Smedje, Sadaaki Shirataki, Bonko Murakami, Rawheya Ahmad Mohamed, Fiona Dunbar, Sarah Shea, Mariko Atsumi, Hideo Matsumoto, Akitoshi Ooya, Seiji Koishi, Yutaka Aoki, Youichi Enseki, Yuri Nakamura, Kostas Francis, Vassilis Kazaridis, Panagiota Kirillidou, Sofia Koukouvinou, Sobharani Paliwal, Parkview Clinic, William Whitehouse, Margo Edwards, Ayliffe Edwards, Sunita Pandit, Judith Powell, Mehdi Tehrani-Doost, Mitra Sepasi, Javad Alaghband-Rad, Reza Rad Goodarzi, Masaki Kodaira, Andrea Viertler, Katja Elpel, Olaf Reis, Melda Ayse Akçakn, Gulsen Erden, Efser Kerimoglu, Eric Lemonnier, Toshio Munesue, Kouhei Mutoh, Kazunori Shimoda, Hideo Nakatani, Yoshifumi Koshino, Isabell Germerott, Eman Galal Sadek, A. G. Litvinov, Froylan Calderón-Castaneda, Alberto Enrique Nuno-Licona, Efren Alatorre-Miguel, Kirstin Goth, Klaus Schmeck, Sibylle Winter, Anja Wiegard, Günter Hinrichs, Denis Köhler, Martin Kammerer, Diana Adams, Brida von Castelberg, Alyx Taylor, Maj-Britt Posserud, Kjell Morten Stormark, Astri J. Lundervold, Christopher Gillberg, Maaike Steijnen, Sophie Verhoeven, Ivana Francula, Igor Prpic, Rena Volga, Stefania Di Biasi, Francesca Piperno, Filomena Puleo, Sara Cerracchio, Roberta Giacchè, Zoé Rein, Nathalie Godart, Fabienne Perdereau, Florence Curt, Philippe Jeammet, Jacques Fermanian, Emine Ozgur Bayman, Yesim Taneli, Neslim Guvendeger, Bulent Ediz, Suna Taneli, Ismet Kan, Angela Plaß, Claus Barkmann, B. Mack, K. Mittenzwei, Peter Riedesser, Michael Schulte-Markwort, Veit Roessner, Andreas Becker, Nicola Hagenberg, Matthias Berking, Tobias Banaschewski, Aribert Rothenberger, Nathalie Coulon, Daniela Tardiola, Stefano Balsamo, Nadia Capriotti, Tanveer Sandhu, Tuula Tamminen, Nina Iovchuk, Ivona Milacic, Oliver Vidojevic, Ayse Kilincaslan, Nahit Motavalli Mukaddes, Gokce Sozen, Ayla Umut, Kenji Yamamoto, Shinko Koishi, Noriko Natsume, Kosuke Yamazaki, Eiji Nanba, Fabienne Naber, Emma van Daalen, Jan Buitelaar, Marinus van IJzendoorn, Sophie Willemsen-Swinkels, Marian J. BakermansKranenburg, Herman van Engeland, Maretha de Jonge, Chantal Kemner, Andrea Caby, Stefan Bendt, Vera Bashina, Maria Krasnoperova, Jan Croonenberghs, Sonja Sliwinski, Armand Christophe, Dirk Deboutte, Michael Maes, Alessia Tosco, Emanuela Giorgi, Monica Lazzarini, M. Liliana Iorio, Mercedes Becciu, Bung-Nyun Kim, Jeong In-Hyoung, Dong-Hyun Ahn, Boong-Nyun Kim, Yun-O Shin, Kang-E Hong, Michal Hrdlicka, Jiri Neuwirth, Vladimir Komarek, Marketa Havlovicova, Zdenek Sedlacek, Marek Blatny, Tomas Urbanek, Masataka Ohta, Yukiko Kano, Yoko Nagai, Anne Wintgens, Jean-Yves Hayez, Seoung-Hu Lim, Ji-Hye Ha, Hee-Jung Byun, Ji-Hae Kim, Rebecca Lee, Eric Fombonne, Eric Taylor, Füsun Çuhadaroôlu Çetin, Deborah James, Maria Lawlor, Nick Sofroniou, Kiyoko Kamibeppu, Lori Sato, Yasutaka Hoshi, Jezdimir Zdravkovic, Petar Kostic, Khalid Murafi, Michael Ries, Rainer Georg Siefen, Martin Jelinek, Helena Klimusova, Jaroslava Blizkovska, C. Burke, B. Doody, Carole Müller Nix, Ayala Nicole, Markus Wilken, Marguerite Dunitz-Scheer, Alexandra Krasnovsky, Anastasia Dressler, Valentina Perelli, Francesca Tinelli, Valentina Rafanelli, Stefania Bargagna, Gerhard Libal, Paul Plener, Jórg M. Fegert, Fumiko Enokido, Masako Higuchi, Istuki Jibiki, Martina Tomori, Hee-Jeong Yoo, Su-Yeon Kim, In-Hee Cho, Sook-Kyeong Yune, In-Kyoon Lyoo, Ji-Hyun Ha, Barbara Haas, Lyudmila Danilova, Kanita Dervic, Janos Csorba, Sandor Rozsa, Marjorie Kleinman, Laszlo Tringer, Max Friedrich, Madelyn Gould, Tuerkan Akkaya-Kalayci, Gerhard Lenz, Elisa Lapponi, Maria Carla Filipponi, Felicia Lauria, Carla Sogos, Akihide Kitamura, Bjoern Albrecht, Xianghui Zhang, Xuerong Li, Vesna Hercigonja-Novkovim, Dubravka Kocijan-Hercigonja, Stephen Ralston, Maria Lorenzo, Asmaa Amin Abdel Aziz, Joseph Biederman, Thomas Spencer, Rodney Moore, Haitao Gao, Josep Cornelld, Natasa Potocnik Dajcman, Rok Holnthaner, Guangrong Xie, Ulrike Sühlfleisch-Thurau, Frank Häßler, Margaret Tiffin-Richards, Michael Richards, Marcus Hasselhorn, Alper Bayrak, R. Rodrigues Pereira, W. Brussel, L. Vlasveld, H. G. Tuynman-Qua, M. J. Lorenzo, Dong-Ho Song, Eun-Hye Ha, Eun-Sik Lee, Young-Min Yu, Hans-Theo Weiler, Heike Hellrung, Caro Grünling, Stephan Overmeyer, Markus Ligges, Bernhard Blanz, Armin Claus, Susanne Walitza, Peter Scheuerpflug, Christoph Wewetzer, Manfred Gerlach, Andreas Warnke, Mieko Aoki, Shozo Aoki, Masato Takii, Yasuko Uchigata, Takehiro Nozaki, Keisuke Kawai, Shu Takakura, Chikako Koreeda, Chiharu Kubo, Hitoshi Saino, Kenzo Denda, Kouichi Ito, Satoshi Asakura, Yukiya Sasaki, Fumi Sasaki, Seishiro Inoue, Sonja Werneck-Rohrer, Ernst Eveline, Heidrun Eichberger, Carolin Prause, Bibiana Schuch, Andreas Lamerz, Jutta Kuepper-Nybelen, Christine Wehle, Gabriele Trost-Brinkhues, Hermann Brenner, Beate Herpertz-Dahlmann, Beata Pawlowska, Maria Chuchra, Marta Kaczynska-Haladyj, Ulrike Margarete Elisabeth Schulze, Simone Schuler, Dieter Schlamp, Peter Schneider, Christian Reiners, Chihiro Morita, Anatoly Severny, Victor Brutman, Irina Kireeva, Marc Schmid, Antje Zander, Marta Kaczynska-Haladyi, Nicole Bruning, Gabriele TrostBrinkhues, Christian Popow, Andreas Karwautz, Sylvia Eimecke, Kristian Holtkamp, Anna Capasso, Masaki Seki, Yu Wakabayashi, Ken Takaoka, Marc G. Schmid, Claudia Zerahn-Hartung, Kayo Morioka, Jan Nedoschill, Peter Leiberich, Thomas Loew, Jae-Suk Jung, Young-Sik Lee, Sun-Ju Chung, Tae-Won Park, Alba Sunshine Bettoschi, Pasquale Carboni, Soo-Churl Cho, Jeong-Mee Ahn, Kang-E. Hong, Jan Elena Kassubek, Sylvia Quiner, Michaela Seyering, Max H. Friedrich, Ana Radojkovic, Ana Velimirovic, Sherese Ali, Kevin Parker, Zarko Martinovic, Nadezda Krstic, Nevenka Buder, Veronika Ispanovic, Ewa Mojs, Maria Danuta Glowacka, Junko Hayashi, Syunichi Funakosi, Takamichi Kamiyama, Takashi Ueno, Tomohiro Ishii, Yutaka Hayashi, Hiroo Matsuoka, William Gardner, Amanda Lucas, David Kolko, Kelly Kelleher, Maria Claustre Jané Ballabriga, Sergi Ballespi Sola, Montse Dorado, Natalia Diaz Reganon, Maite Gonzalez Alonso, Maria Dolores Riba, Edelmira Domenech Llaberia, Kayano Ishii, Kayo Inoko, Aya Nishizono-Maher, Makiko Osawa, Mari Kasahara, Kazuhiko Saitou, Satomi Murase, Risa Oga, Takashi Murakami, Shuji Honjo, Hitoshi Kaneko, Shiori Arai, Sabine Völkl-Kernstock, Sonja Bauch-Prater, Martha Feucht, Paula Vilariça, Isadora Pereira, Olivia Pastor, Susana Farinha, Pedro Caldeira, Maria Antónia Silva, Caterina Gawrilow, Peter M. Gollwitzer, Keun-Ah Cheon, Young-Hoon Ryu, Jae-won Kim, Alceu Gomes Correia Filho, Luis Augusto Rohde, Tatiana Silva, Rafael Bodanese, Michael Aman, W. Boudewijn Gunning, Manfred Laucht, Mahha El-Faddagh, Martin Schmidt, Jakob Nützel, Juliane Ball, Cornelia Elben, Halina Kadziela-Olech, Taewon Park, Myung Ho Im, Daehee Kang, Hee Jeong Yoo, David Michelson, Shuyu Zhang, Dustin Ruff, Peter Feldman, Niels Bilenberg, Jurgen Jensen, Azar Moradi, Vahed Alaey, Christopher Kratochvil, Timothy Wilens, Laurence Greenhill, Douglas Gelowitz, Leon Patrice Celestin, Smadar Celestin-Westreich, Somnath Banerjee, M. Chandola, S. Venables, Hideki Negoro, Junzo Lida, Hidemi Iwasaka, Masanori Kyo, Tatsushi Nagano, Kanae Kishino, Toshihumi Kishimoto, Bong-Suk Kim, Jun-Won Hwang, Masanori Kyoh, Lida Junzo, Negoro Hideki, Nagano Tatsushi, Kishino Kanae, Iwasaka Hidemi, Kishimoto Toshifumi, Rael Strous, Simion Kertzman, Z. Ben Nachum, Moshe Kotler, Roni Hegesh, David Coghill, Quentin Spender, Joanne Barton, Chris Hollis, Cammy Yuen, Irina Cleemput, Lieven Annemens, Susanne Eschmann, Karl Christoph Käppler, Maycoln M. L. Teodoro, Eva Stieger, Anouk Mugier, Stephanie Stüttler, Cord Alexander Heise, Henrik Uebel, Charlotte Hanisch, Kerstin Konrad, Ralph Radach, Dagmar Horn, Noa Tsujii, Akira Okada, Noriko Kuriki, Junko Matsuo, Kazushi Hanada, Takeshi Kusube, Kazuhiko Hitomi, Marcelo Schmitz, Daniel Denardin, Tatiana da Silva, Thiago Pianca, Tatiana Roman, Mara Hutz, Asma Bouden, Ines Dengezli, Mohamed Halayem, Oscar Herreros, Francisco Sanchez, Belen Rubio, Ramon Gracia, Simone Henrike Weber, Alex Wolters, Albert J. Allen, Roger Kurlan, Donald Gilbert, David Dunn, F. Randy Sallee, Christine Thomason, Virginia Sutton, Denai Milton, Dorthe Petersen, Solvejg Kristensen, Jörg Kinkelbur, Juliane Hellwig, Martin Hellwig, Eckert Rüther, Olayinka Omigbodun, O. Esan, K. Bakare, B. O. Yusufi, F. Nuhu, A. Adesokan, Marie Kopecky-Wenzel, Mark-Peter Steenhuis, Ruud Minderaa, Marie-Louise Körlof, Margit Wängby, Lars R. Bergman, Suwei Yu, Petteri Multimäki, Kai Parkkola, Andre Sourander, Georgios Nikolakaros, Hans Helenius, Carina Freitas, Assunçâo Rocha, Lídia Pocinho, Shinichi Arai, Hironobu Ichikawa, Ikuko Hirosawa, Maria Elena Mdrquez-Caraveo, Verónica Pérez-Barrón, Merete Juul Sorensen, Ole Mors, Per Hove Thomsen, Kai von Klitzing, Sonja Perren, Agnes von Wyl, Dieter Burgin, Han-Ik Yoo, Min-Sup Shin, Kang E. Hong, Ehsan Syed, Sobia Haqqi, Michail Semago, Sigita Girdzijauskiene, Dainius Puras, Grazina Gintiliene, Dovile Cerniauskaite, Christiane Bormann-Kischkel, Rosemarie Schmoetzer, Diana Frischholz, Martin Linder, Catharina Ganseforth, Daniela Rödder, Angela Kribs, Frank Pillekamp, Alexander von Gontard, Bernhard Roth, Tjhin Wiguna, Cristina Maria Ribeiro Marques, Teresa Goldschmidt, Teresa Cepeda, Ayse Arman, Refika Ersu, Dilsad Save, Goksin Karaman, Koray Karabekiroglu, Bulent Karadag, Meral Berkem, Lene Ruge Moller, Parathasarathy Biswas, Anil Malhotra, Nitin Gupta, Tord Ivarsson, Oeystein Litlere, Per Svalander, Yelena Yelikova, Petar Nastasic, Snezana Filipovic, Roza Panoski, Goran Lazetic, Nataliya Zvereva, Monika Strauss, A. Graf, R. Zollinger, Tanja Brückl, Michael Höfler, Lena Schwenden, Hans-Ulrich Wittchen, Roselind Lieb, Angelika Schweitzer, Jane Edwards, Monika Schlögelhofer, Paul G. Amminger, Maria Giuseppina Ledda, A. Zuddas, T. Piroddi, M. Abis, A. Mereu, Fabian Härtling, Ralf Tepest, Tanja Goncharova, David E. D. Linden, Peter Falkei, Kai Vogeley, Fritz Poustka, Miriam Spinner, Julian Dobranowski, Duncan MacCrimmon, Jim Gibson, Susan Fawcett, Margarita Criollo, Brigitte Ramsauer, Nina Janke, Danica Boskovic Djukic, Fabiola Napoli, Raffaella Valente, Valeria Neri, Mauro Ferrara, Carla D’Agostini Costa, Christian Veronesi, Sergio Melogno, Achille Gigliotti, Bruna Mazzoncini, Antonio Fonseca, Eva Maid, Erika Hohm, Claudia Mehler-Wex, J. Catharina Duvigneau, Romana T. Hartl, Dorit Ben-Shachar, Harvey Kranzier, Sanjiv Kumra, Ginny Gerbino-Rosen, David Roofeh, Courtney De Thomas, Carolyn Dombrowski, Marjorie McMeniman, Hsueh-Ling Chang, Sue-Huei Chen, Keh-Chiang Yu, Michael Kölch, Reinhild Bücheler, Christoph H. Gleiter, Stephanie P. Bohne, Frank M. Häßler, Bärbel Gierow, Julie Carbray, Sampson Gwen, Michael Naylor, Anja Taanila, Katri Hautala, Päivi Kemppainen, Arto Kotimaa, Hanna Ebeling, Irma Moilanen, Monica Biscaldi, Bettina Wagner, Ute Dürrwächter, Susanne Trauzettel-Klosinski, Jens Reinhard, Ellen Plume, Gerd Schulte-Körne, Branko Aleksic, Regula Blaser, Ulrich Preuss, Claudia Meusel, Georg Macharey, Ulrich Strehlow, Johann Haffner, Jürgen Bischof, Volker Gratzka, Peter Parzer, Franz Resch, Steffi Sachse, Beatrice Anke, Monika Adamski, Angelika Pecha, Dragana Macesic-Petrovic, Svetlana Slavnic, Chie Hatagaki, Hanna Swaab, P. Cohen-Kettenis, Roberta Di Scipio, Ester Patruno, Sylvia Reinelt-Straka, Liselotte Hoffmann, Max H. Friedrich Dragana, Macesic Petrovic, Monique Nesa, David Hay, Clare Roberts, Mairead McCoy, Harriet Salbach, Uta Klopfer, Swantje Hagen, Bürger Arne, Ulrike Lehmkuhl, Bradley Smith, Judith Sinzig, Martin Hohmann, Takayo Mukai, Pia Enebrink, Niklas Ldngström, Henrik Andershed, Louis Richer, Lise Lachance, Claude Dubé, Serge Saintonge, Matti Virkkunen, Jyrki Liesivuori, Risto Bloigu, Jari Tiihonen, Alasdair Vance, Chidambaram Prakash, Magali Reyes-Harde, Krisztina Csaba, Marielle Eerdekens, Roza Olah, Ilse Augustyns, Ulrike Hellmann, Astrid Matei, Ji Hyun Ha, In Hee Cho, Mee Gyeong Kim, Sook Kyeong Yune, In Kyoon Lyoo, Bruce Barbro, Guilherme Polanczyk, Zineb Iraqi, Nadia Kadri, Driss Moussaoui, Kamal Raddaoui, Karl Titze, Susanne Wollenweber, Verena Nell, Andreas Wiefel, Margarita Forcada Guex, Basaran Sezer, Farshid Shamsaei, Fatemeh Cheraghi, Oytun Hasturk, Mehmet Okan, Naoko Sato, Aya Sato, Eleonora Camillo, Viviana Porcari, Maria Patrizia Salatiello, Sabrina Chifari, Valentina Dell’Oglio, Militello Rosanna, Carmela Scrò, Lisette Hart-Kerkhoffs, A. Ph. van Wijk, L. M. C. Jansen, Robert Vermeiren, Theodore Doreleijers, Shi Ji Zhang, Reija Latva, Liisa Lehtonen, Raili Salmelin, Emmanouel Tsalamanios, Gerasimos Kolaitis, Elena Paliokosta, Stauroula Diareine, Sofia Anasontzi, Alkis Tsiantis, Irini Limbinaki, John Tsiantis, Leontina Dreana-Ianciu, Miriana Vrajitoriu, Laura Lebedeva, Yasemen Taner, Betul Bakkaloglu, Füsun Çuhadaroâlu Çetin, Cengiz Ozbesler, Mihriban Erturk, Sandra Sebre, Audrey Keller, Ayala Borghini, Blaise Pierrehumbert, François Ansermet, Adrian Furnham, Peter Noack, Bruce Kirkcaldy, Michaela Felber, Stefan Puig, James Swain, James Leckman, Linda Mayes, Ruth Feldman, Robert Constable, Robert Schultz, Evgeny Koren, Umaporn Trangkasombat, Michael Karle, Marina Belianchikova, Galina Scoblo, Valentin Fadeev, Lyne Jaunin, Francois Ansermet, Tatsuo Ujiie, Kenji Nomura, Yasuko Sasaki, Vaska Stancheva-Popkostadinova, Meglena Achkova, Emine Kilic, Gönül Erdogan, Rami Gaber, Areej Qasqas, Martin Aßhauer, Hubertus Adam, Lynne Jones, Linda Rachidi, Kawtar Halty, Omar Battas, Agnes Leor, Shmuel Tyano, Schaul Shreiber, Nan Hosogane, Kyoto Watanabe, Makiko Okuyama, Young-Shin Kim, Bennett Leventhal, Yun-Joo Koh, W. Thomas Boyce, Sonja Liptai, Marianne Clauß, Petra Heuer, Abdul Nasser Kaadan, Samuel Menahem, Frances Salo-Thompson, Bizhan Shabankhani, Christoph Hoeger, Seong-Shim Jeong, Jeong-Hwan Park, Eduardo Szaniecki, Lise Roll-Pettersson, Patrick Ehnis, Maria Trosse, Piedade Van Rebelo, Eva Heimdahl Mattson, Giulietta Cucchiaro, Mariadonatella Cocuzza, Giada Morales, Nataliya Bobrova, Fernando Asbahr, Renato Ramos, André Costa, Roberto Sassi, Maaike Nauta, Sonila Tomori, Valbona Alikaj, A. Como, Lisa Snider, Marjorie Garvey, Dirce Zanetta, Helio Elkis, Susan Swedo, Pinar Vural, Kai Wang, Yan Zhu, Osman Sabuncuoglu, Viktoryia Krasavina, Nina Pykhtareva, Bianca Venuti, Naohiko Tachi, Naomi Kodoi, Naoko Sakamoto, Michiko Watanabe, Motiko Goto, Frank Geller, J. Reinlein, Nikolaus Barth, F. Hahn, Anke Hinney, Monika Robatzek, Rosa Calvo, Lazaro Luisa, Lucrezia Cirigliano, Loredana Lucarelli, Uwe Ratz, Thomas Stegemann, Ulla Breuer, Susanne von Widdern, Leonie Fricke, Alexander Mitschke, Alfred Wiater, Gerd Lehmkuhl, Kyoichi Honda, Muhmmad Lafta, Secil Oktem Kurultak, S. Tomori, and E. Petrela

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2004
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38. Symposia

Author

Christoph Correll, Stanley P. Kutcher, John McClellan, Jan Buitelaar, Elizabeth Pappadopulos, Aribert Rothenberger, Fritz Mattejat, Stephen Scott, John Weisz, Eberhard Schulz, Wilhelm Felder, Christian Fleischhaker, R. Böhme, B. Sixt, Rutger Jan van der Gaag, Laurence Y. Katz, Brian J. Cox, Shiny Gunasekara, Alec L. Miller, Nathaniel Laor, Peter Riedesser, Ernesto Caffo, James Leckman, Massimo Ammaniti, Giampaolo Nicolais, Mario Speranza, Hans Steiner, Laura Delizonna, Astrid Schallauer, Margo Thienemann, Alexander C. McFarlane, Miranda van Hooff, Michael Sawyer, Carlo Cianchetti, Naoufel Gaddour, Mokni Sana, Mechri Anouar, Letaief Mondher, Gaha Lotfi, Fabian Härtling, Robert Bittner, Corinna Haenschel, Marcus Cap, Tanja Goncharova, David E. J. Linden, Ralf Dittmann, Anneliese Maestele, Claudia Mehler, Eberhard Meyer, Jack A. Jenner, Leonie Boeing, Val Murray, Anthony Pelosi, Robert McCabe, Douglas Blackwood, Robert Wrate, S. Pellerano, M. Pintor, G. L. Mellis, T. Piroddi, Alan Flisher, Monique Nesa, Rosanna Rooney, Clare Roberts, Robert Kane, Sven Silburn, Lisbeth Pike, Helge Staby Deaton, Stuart Lustig, Michelle Funk, Anne Rickards, Dinah Reddihough, Roslyn Wright-Rossi, Jacqui Simpson, Dieter David Seuthe, H. Vielhaber, Kinderklinik Dritter Orden, H. Backmund, M. Gerlinghoff, Mary Schwab-Stone, Ine Jespers, Robert Vermeiren, Vladislav Ruchkin, Marek Blatny, Michal Hrdlicka, Tomas Urbanek, Martin Jelinek, Veronika Balastikova, Philippe Jeammet, Alain Frottin, Andjelka Filipovic, Eric Albert, Dora Musetti Schelotto, Mladen Knezevic, Milivoj Jovancevic, Jonathan Hill, Maria Lawlor, Christian Kienbacher, Carolin Prause, Margit Stöckl, Gertrude Bogyi, Max H. Friedrich, Michael Klein, Katrin Kürschner, Lynne Murray, Victoria Leidecker, Helen Sharp, Ilona Luoma, Pälvi Kaukonen, Tuula Tamminen, Barry Nurcombe, Graham Martin, Brett McDermott, Franz Resch, Benno Graf Schimmelman, Jane Edwards, Patrick D. McGorry, Martin Lambert, Philippe Conus, Ulrich Preuss, Dieter Bürgin, Monika Strauss, Peter Parzer, Georg Spiel, C. von Korff, H.-A. Ballin, R. Gößler, M. Günter, G. Sange, Heiner Meng, Eginhard Koch, Klaus Minde, Mary True, L. Pisani, F. Oumar, J. Padilla, Jean-François Bouville, Wendy Vogel, Klaus Schmeck, Kirstin Goth, Diane Purper-Ouakil, Véronique Dessons, Catherine Doyen, Fernando Perez-Diaz, Marie-Christine Mouren-Simeoni, Andreas Karwautz, Gudrun Wagner, Klaus Schwienbacher, Maria Haidvogl, Gerald Nobis, Janet Linda Treasure, David Andrew Collier, Romuald Brunner, A. Hueg, Johann Haffner, Marc Schmid, Lutz Goldbeck, Jakob Nützel, Volkmar Höfling, Karin Schermelleh-Engel, Helfried Moosbrugger, Josep Tomàs, Josep Cornellà, Alex Llusent, Anna Bielsa, Myron Belfer, Brian Robertson, Custodia Mandlhate, Birama Seck, Barbara Zwirs, Huib Burger, Tom Schulpen, A. Karem Salman Al-Obedy, Oleh Romanchuk, Irena Namyslowska, Björn S. Reigstad, Kirsti Margrethe Jorgensen, Walter Matthys, John Lochman, Marjo Zonnevylle-Bender, Nicolle van de Wiel, Angela Wagner, Christine Jennen-Steinmetz, Christopher Goepel, Irene van Bokhoven, Stephanie van Goozen, L. Patt Franciosi, Leode Graaf Acquoy, Anne Tischlinger, B. Pharm, Knut Halyard Bronder, Kari Schleimer, Joachim Walter, Boia Ephraime, Tatjana Dmitrieva, Alvaro Seligman Silva, Katja Becker, Hans-Christoph Steinhausen, C. Winkler Metzke, Erikson F. Furtado, Manfred Laucht, Oliver Bilke, Petra Zimmermann, Hans-Ulrich Wittchen, Roselind Lieb, Helga Hannesdottir, Thorarinn Tyrfingsson, Manfred Döpfner, Kurt Hahlweg, Annett Kuschel, Heike Bertram, Nina Heinrichs, Inez Freund-Braier, Gabriele Brix, Christopher Hautmann, Julia Pluck, Alfons Crijnen, Pol van Lier, Patricia Vuijk, Reiner Frank, Inger Helene Vandvik, Rainer Schäfert, Jeanne van Weel, Jan Schieveld, Jörg M. Fegert, William Friedrich, Smadar Celestin-Westreich, Leon Patrice Celestin, Ingrid Ponjaert-Kristoffersen, Keizo Nagao, M. Kisida, E. Shindo, Helmer Baying Larsen, Karin Helweg-Larsen, Ramón Lindauer, Jan Booij, Miranda Olff, Gerard den Heeten, Berthold Gersons, Frits Boer, Eric Schoentjes, Sarah Bal, Michael Schulte-Markwort, Tytti Solantaus, Sini Toikka, Maarit Alasuutari, Barbara Steck, Andrea Grether, M. Ehrensperger, Felix Amsler, L. Kappos, Rina Saha, Bela Paschen, Christiane Baldus, Miriam Haagen, Martina Pott, Georg Romer, Yoshiro Ono, H. Homma, Y. Ishida, H. Ide, M. Okamoto, S. Kameoka, Hiroshi Nakayama, A. Yamamoto, Nahit Motavalli Mukaddes, Sam Tyano, Tamar Mozes, R. Caplan, Savita Malhotra, Maria Giuseppina Ledda, Al Fratta, S. Mannino, Simona Corona, A. Zuddas, Macarena Marin Olalla, Ruth Garcia, Bernardo Perez Ramirez, Ross Campion, Peter Hindley, Nitin Gupta, Anish Bhattacharaya, Mehak Kapoor, G. van de Willge, Silke Klemm, S. Smesny, M. Stockebrand, S. Grunwald, Femmie Juffer, Marinus H. van Ijzendoorn, Marian J. Bakermans-Kranenburg, Ute Ziegenhain, B. Derksen, R. Dreisörner, Daniel Gutschner, Martin Maldonado-Duran, Manuel Ferndndez-Criado, Felicia Heidenreich, Marie Rose Moro, Charles Millhuff, Kirby Pope, Frank Theisen, Hubertus Himmerich, T. Kraus, A. Schuld, T. Pollmächter, Alan Apter, D. Gothelf, A. Brand-Gothelf, Gidi Ratzoni, L. Kikinzon, A. Weizman, Yuval Bloch, Michael Haberhausen, Daniel Müller, John Fayyad, Altino Bessa Marques Filho, Adolfo Bezerra de Menezes, John Campo, Sheree Shafer, Jennifer Strohm, Amanda Lucas, David Shaeffer, Harold Altman, Christine Gelachek, Naoyasu Motomura, Yozo Takino, Masahiro Iwakiri, Patrick Pössel, Simone Seemann, Martin Hautzinger, Theodore Mutale, Christian Haase, Majid Ali Abidi, Shehla Raheem, Leyla Faw, Aaron Hogue, Howard Liddle, Kirsten Catthoor, Joost Hutsebaut, Donald Jasinski, Douglas Faries, Rodney Moore, Annette Streeck-Fischer, Renate Sannwald, Gottfried Maria Barth, Christoph Schwarz, Monika Staigle, Manh-Hiep Pham, Dario Balanzin, Joelle Materi, Pia Eresund, Alexander Mokhovikov, Sandra Stankovic, Kerim Munir, Nese Erol, Füsun Çuhadarodlu Çetin, Angela Hassiotis, Martine Flament, Michael Scholz, Maud Rix, Franziska Nestler, Annegret Selisko, Nathalie Godart, Fabienne Perdereau, Zoé Rein, Florence Curt, Jane Akister, Pei-Chin Peggy Lee, Sho-Man Susan Tsai, Lai-Shiun Ho, Su-Chun Wu, Jacques Miermont, Joel Swenson, Mardjane Teherani, Bruno Falissard, Jean Cottraux, Julia Plück, Robert Oades, Mirjam Simons-Sprong, P. F. Schothorst, J. T. Swaab-Barneveld, Stephanie Juran, Matthias Weisbrod, Eric Chen, Bernd Röpcke, Smiljka Popovic-Deusic, Luise Poustka, Nele Wild-Wall, Mechthilde Papousek, Mirelle Keren, Ruth Feldman, S. Maestro, A. Chilosi, C. Pecini, L. Pfanner, Laurence Greenhill, K. Jahnsen, L. T. W. Jong-van den Berg, J. M. Zito, Kelly Posner, Anne Skrobala, Pablo Goldberg, Lisa Kotler, Robert Findling, Regina Bussing, Kapil Sayal, Geoffrey Mitchell, Michael Huss, Barbara Högl, Renate Grimmlinger, Karl Christoph Käppler, Maycoln M. L. Teodoro, Sylvia Hiromi Oswald, Janine M. Dagnoni, M. I. Pinheiro, C. T. Heleno, R. Rothe-Neves, V. G. Haase, A. Del Prette, Marimilia Rodrigues Lambertucci, J. L. Rodrigues, P. M. Freitas, C. A. P. Lourenco, H. C. W. Carvalho, J. Baumeister, M. Weisenhorn, S. Stadelmann, S. H. Oswald, H. Ruder, Ciro Ruggerini, Stefania Vicini, Enrico Pupulin, Antonio Guidi, Kaija Puura, Mirjami Mäntymaa, Kai von Klitzing, Orna Rosvald, Hans-Ludwig Kröber, A. Stöver, R. Proske, Rainer Semmelbeck, Marc Walther, Matthias Schmelzle, Monika Egli-Alge, Richard Beckett, Constanze Gerhold, Lieselotte Turkmen-Barta, Colette Chiland, Heino Meyer-Bahlburg, Domenico Di Ceglie, Ulrike Lehmkuhl, Orlando Uccellini, Mario Bertolini, Francesca Neri, Delia Albanese, Raffaella Bertola, Maartje Snoek, Martien Kas, Ulrike Margarete Elisabeth Schulze, Silke Calame, Ferdinand Keller, Stephanie Santel, Kerstin Krauel, Michael Rotte, Thomas F. Münte, Annemarie van Elburg, Fritz Poustka, Sven Bölte, Sabine Feineis-Matthews, Sven Boite, D. Hubl, D. Prvulovic, T. Dierks, Sabine Klauck, Irma Moilanen, M. Mattila, J. Laurila, K. Jussila, A. Pyper, S. L. Linna, Hanna Ebeling, D. Pauls, Pirjo Korpilahti, Soile Loukusa, Eira Jansson-Verkasalo, Johannes Hebebrand, Beate Herpertz-Dahlmann, Anke Hinney, Anne-Kathrin Wermter, Susann Friedel, Frank Geller, Helmut Schafer, Fernando Fernandez-Aranda, Joanna Holliday, Kristian Holtkamp, C. Mika, M. Heer, Rudolf Uher, Nicole Barbarich, Shannan E. Henry, Ursula Bailer, Guido Frank, Walter H. Kaye, Elisabet Wentz, J. Hubert Lacey, Glenn Waller, Maria Rastam, Jeremy Turk, Christopher Gillberg, Frank C. Verhulst, Marieke Zwaanswijk, Peter Verhaak, Jozien Bensing, Jan van der Ende, Frank Verhulst, Andre Sourander, Paivi Santalahti, Tamsin Ford, Robert Goodman, Howard Meltzer, Inge Seiffge-Krenke, Richard Fritsch, Marika Cutler, E. James Anthony, Per-Anders Rydelius, Rolf Castell, Milica Pejovic-Milovancevic, Miroslav Pavlovic, Noa Kalman, Muli Linder, Ido Luria, Yechiel Levkovitz, Kosuke Yamazaki, Pedro Caldeira da Silva, Grata Santos, Filipa Martins, Yen-Nan Chiu, Wen-Jer Tsai, Shur-Fen Gau, Chang-Chang Tseng, Shu-Chen Su, Jan Croonenberghs, Lucas Brouw, Annick Wauters, Nicole Bruning, Zina Manjaly, Gereon Fink, Olivera Aleksic, Nenad Rudic, Lucres Jansen, Christine C. Gispen-De Wied, Bertine Lahuis, Hanna Swaab, Jolijn Pietersen, Carolien Gevers, Inge Kamp-Becker, Isabell Germerott, Patricia Howlin, null Gaudière, Barbara Forresi, G. Lepri, Soumaila Laval, Andreas Wiefel, Z. Biringen, Karl Titze, K. Lenz, C. Seither, B. Witte, Marguerite Dunitz-Scheer, Markus Wilken, Alexandra Krasnovsky, Peter Scheer, Maria Cordeiro, Filippo Muratori, B. Felloni, A. Cesari, Linda Helmig, Peter Fonagy, Chris Moody, Jim Fultz, René Glanzmann, Nathalie Lutz-Latil, Agnes van Wyl, Dainius Puras, Amaia Hervds, John Tsiantis, T. Dragonas, H. Davis, V. Ispanovic, A. Paradisiotou, Mimoza Shanini, Lynne Jones, A. Uka, A. Rrustemi, Anne-Liis von Knorring, Dirk Deboutte, Souraya Dorhmi, Mohamed Agoub, Driss Moussaoui, Omar Battas, Inger Halvorsen, Anne Andersen, Sonja Heyerdahl, Denise Baillot, Michele La Roche, Claudia Furino, Annick Buchholtz, Gary Goldfield, Katherine Henderson, Ulrich Hagenah, Varinja Blume, Marlene Flacke-Redanz, Beate Herpertz Dahlmann, Angelique A. Sallas, Hubertus Adam, null Mozambique, Aferdita Goci-Uka, Susanne Schlüter-Müller, Umesh Bawa, Fakhri Khalik, Nima Forouher, Miyuki Sadamatsu, null Nanba, Nobumasa Kato, Kiyoto Kasai, Eiji Nanba, Martin H. Schmidt, Günter Esser, Herman van Engeland, Sophie Willemsen-Swinkels, Claudine Dietz, Anne Claire Beernink, Oliver Vidojevic, Ivona Milacic, Rael Strous, Roni Hegesh, Simion Kertzman, Z. Ben-Nahum, Moshe Kotler, Emma van Daalen, Mijke Zeegers, Hilleke Hulshoff Pol, Charles Williams, Jessica Sank, Martha Paulk, George Schwarz, Paul Wharton, Marija Raleva, Kamka Paketchieva, Angelina Filipovska, Carole Müller Nix, Margarita Forcada Guex, Abdel-Mohsen Daigham, Marit S. Indredavik, Torstein Vik, Siri Kulseng, Ann-Mari Brubakk, Marion Cuddy, Katharine Riley, Brigitte Vollmer, John Wyatt, Robin Murray, Mika Soininen, E. Juulia Paavonen, Mika Fjällberg, Juha Salmi, Almgvist Fredrik, Eeva T. Aronen, Olaf Reis, Stephanie P. Bohne, Susanne Kraenz, Dong-Hyun Ahn, Tae-Ho Kim, Jun-Ho Choi, Yun-Young Kim, Ivan Begovac, Milena Skocic, Vlasta Rudan, Oleg Filipovic, Tomasz Wolanczyk, Anita Brynska, Stanislaw Wojtowicz, Salvador Celia, Cisca Aerts, Elisabeth Cleve, Hellmut Hartmann, Hans-Jürgen Kühle, Fridjof Heidorn, Solveigh Zeyer, Joaquin Fuentes, Andrés Martin, Denis G. Sukhodolsky, Riittakerttu Kaltiala-Heino, Matti Rimpelä, Henrik Andershed, Deborah O’Donnell, Michelle Pearce, Dieter Burgin, Andreas Becker, Nicola Hagenberg, Matthias Berking, Veit Roessner, Ketil Hanssen-Bauer, Odd Aalen, Jürgen Junglas, Yoon-Seok Huh, Yun Young Kim, Kyung-Ja Oh, Kai Wang, Michael Tarren-Sweeney, D. M. Leiblum, Renate Kühl, Cornelia Nötzel, Ernst Pfeiffer, Klaus Lenz, Agneta Rosling, Marianne Poller, Donna Cross, Simone Klabin, Diana Kaplan, Lars Mickel, Gerd Lehmkuhl, Regina Möckel, Shani Leor, Leor Frisch, Amos Frisch, Abraham Weizman, Andrey Zanozin, Sylvie Jamart, Jean-Yves Hayez, Agnes Leor, Maria Elisabeth Ahle, Galit Ben Amitay, Irene Kosov, Ahuva Reiss, Moses Tamar, Hans Smedje, Hiie Allik, Jean Steyaert, Dries Castermans, John Creemers, Koenraad Devriendt Marta Kaczynska-Haladyj, Maria Claustre Jané Ballabriga, Joaquima Judez, Empar Pelaez, Pilar Sole, Lidia Rodriguez, Saskia Palmen, Chantal Kemner, Hugo Schnack, Rene Kahn, Anna Fabrizi, Levi Gabriel, Marcos Mercadante, Sergiode Paula Ramos, Maria Concecao Rosario-Campos, Michael Rutter, Stephan Collishaw, Barbara Maughan, Andrew Pickles, Julie Messer, Avshalom Caspi, Terrie Moffitt, Jana Kreppner, Anne Inger H. Borge, Suniya Luthar, Stephanie Hamarman, C. Ulger, J. Fossella, M. Brimacombe, J. Dermody, Mark Stein, L. D. Waldman, C. Sarampote, A. Robb, E. H. Cook, Aiveen Kirley, N. Lowe, Z. Hawi, C. Mullins, G. Daly, I. Waldman, M. McCarro, null O’Donell, Emma van der Meulen, S. C. Bakker, D. L. Pauls, R. J. Sinke, Guilherme Polanczyk, C. Zeni, J. P. Genro, Tatiana Roman, Mara Hutz, Christa Schaff, Patrick Haemmerle, Harald Sontag, Agnes Vetro, Julia Gadoros, Gotthard Roosen-Runge, Jocelyn Hattab, Peter Hummel, Orna Braun-Lewensohn, Daniel Schechter, Charles Zeanah, Michael Myers, Michael Liebowitz, Mark Davies, Wei-Tsuen Soong, Deborah James, Nick Sofroniou, Marine Gegelashvili, Umesh Parikh, John M. Kane, Anil K. Malhotra, Manoj Shah, Richard R. Pleak, Ronen Hizami, David Michelson, Marina Danckaerts, Alessandro Zuddas, Shuyu Zhang, Philip Hazell, P. Zeiner, M. Johnson, Frank Häßler, Prasad Suyash, Edmund Sonuga-Barke, Lynne Poole, Sarah Mares, Jon Jureidini, Zachary Steel, Louise Newman, Torsten Lucas, Stephanie Paulus, Martin Aßhauer, Birgit Miller, Gunilla Jarkman Björn, Christina Bodén, Per Gustafsson, Viola Povse Ivkic, Lazar Tenjovic, Radosavljev Jelena, Smiljka Popovic Deusic, Philip Graham, Henrikje Klasen, Jacinta Tan, Tony Hope, Anne Stewart, Raymond Fitzpatrick, Michael Kölch, Angeles Diaz-Caneja, Sonia Johnson, Ines Dippold, Katja Wiethoffi Ferdinand Keller, Sue Bailey, Nathan Whittle, Klaus Hennighausen, Gregor Kohls, Verena Maas, Tanja Rinker, Swantje Zachau, Gabriele Christmann, Anna Jaremkiewicz, Michael Schecker, Waldemar von Suchodoletz, Ruth Uwer, Ronald Albrecht, Lisa Glass, Valéria Csépe, Ferenc Honbology, Anett Rago, Eva Mészdros, Richard G. Schwartz, Valerie L. Shafer, Jonathan Green, C. Jacobs, L. Kroll, J. Briskman, G. Dunn, J. Beecham, B. Tobias, L. Baird, Terje Ogden, Michael Fitzgerald, Mark Bellgrove, Michael Gill, Ian H. Robertson, Paul McArdle, Amanda Burke, K. Michael Hong, Christina Hoven, Danuta Wasserman, Katharina Braun, Jórg Bock, Carina Helmecke, Michael Gruß, Gerd Poeggel, Charles Marsden, S. Muchimapura, M.-C. Pardon, M. Bianchi, Joram Feldon, Daniela Rüedi-Bettschen, Andrea C. Dettling, Christopher R. Pryce, Hans-Willi Clement, O. Sommer, A. Pschibul, C. Rombach, M. Gerlach, Claudia Mehler-Wex, S. Zeiske, E. Grünblatt, G. Gille, D. Rausch, Manfred Gerlach, Amira Seif El-Din, Nadia Kadri, Houda Hjiej Andaloussi, Khadija Chihabeddine, Mohammed Almaqrami, Alexander von Gontard, M. Okuno, Kurt Quaschner, Niels Bilenberg, Carsten Obel, Tine Brink Henriksen, Morten Hedegaard, Niels Jurgen Secher, Jorn Olsen, Antonio Fonseca, Isabelle Nathalie Koch, Ieva Bite, Phyllis Cohen, Katrin Russell, Nichaela Broyden, Gillian Lancaster, Christina Eichhorn, Karola Tiedtke, Ronald Feldman, Andreas Warnke, Peter Scheuerpflug, V. Vetter, Jürgen Bartling, Kerstin Konrad, Susanne Neufang, Charlotte Hanisch, Gereon R. Fink, Sarah Durston, Matthew C. Davidson, Nim Tottenham, Julie Spicer, Adriana Galvan, John Horvitz, John A. Fossella, Richard Watts, B. J. Casey, Daniel Brandeis, Andreas J. Fallgatter, Ann-Christine Ehlis, Jürgen Seifert, W. K. Strik, K. E. Zillessen, Martin J. Herrmann, Gerd Schulte-Körne, Heikki Lyytinen, Tomi Guttorm, Anna-Maija Poikkeus, Kenneth M. Eklund, Paula Lyytinen, Minna Torppa, M.-L. Laakso, E. Leskinen, A. Tolvanen, Silvia Paracchini, J. Schumacher, I. R. König, Claudia Libertus, Heide Griesemann, A. Kleensang, A. Ziegler, P. Propping, M. Näthen, Leo Wolmer, Iyad Zagout, Esti Galili-Weisstub, Gene Fisch, Ann Swillen, Annick Vogels, Christine Freitag, Jean-Francois Bouville, Laetitia Atlanti-Duault, Thierry Baubet, Robyn Osrow, Marie-Madeleine Leplomb, Yves Marchandy, Malika Bennabi, Ricardo Halpern, Odon Monteiro, Abbey-Robin Durkin, Rudy Haapanen, Susanne Bauer, Max Friedrich, Christina Stadler, Philipp Sterzer, Andreas Kleinschmidt, Irene Nowraty, W. E. Müller, Ulrich Knölker, Gabriele Schmid, Swantje Berndt, B. Behn, Jan Hendrik Puls, Luc Stevens, Joachim Jungmann, Zoran Juretic, Nela Ercegovic, Renate Schepker, Füsun Çuhadaroglu-Çetin, G. Herhaus, S. Melfsen, Daomeng Cheng, Donald Harder, Harry Laws, Yoshibumi Nakane, Kenzo Takeshita, Hiroshi Naruse, Yan Zhu, Jun Liu, Yasong Du, John Sikorski, Sannie Hamerlynck, Lisettet Hart, Lucres Nauta-Janssen, Prathiba Chitsabesan, Hien Nguyen, Jovan Simeon, Cathy Cuzner, Howard Schachter, Ana Soledade Martins, Chirstian Kieling, Julia Comassetto, Renata Goncalves, Silvia Oswald, Johannes Buchmann, J. Kirschner, M. Garvey, Gunther Moll, Hartmut Heinrich, Sameer Malhotra, Zeffie Poulakis, Sam Menahem, Karin Sauer, Tilouch Samia, Hannachi Rimeh, Missaoui Sonia, Mara Westling Allodi, Monica Biscaldi, Bettina Wagner, Chiyoko Uchida, Thomas Jozefiak, Roberta Penge, Valentina Ivancich Biaggini, Siv Fischbein, Matti Joukamaa, Anja Taanila, Juha Veijola, Juha T. Karvonen, Jouko Miettunen, Edelmira Domenech Llaberia, Teresa Corbella Domenech, Maria Claustre Jane Ballabriga, Josepa Canals Sanz, Griselda Esparo, Sergi Ballespi Sola, Xuejun Liu, Yukiko Kano, Masataka Ohta, Yoko Nagai, Takashi Arai, Su Linyan, Jeff Bridge, Boris Birmaher, Carlo Di Lorenzo, Satish Iyengar, David Brent, Bernhard Blanz, Laura Weninger, Gerhard Libal, Anna Skrabal, Michael Bowden, Howard Cooper, Inger Simonsen, Carl Bechstrom, Mette Medby, Ritva Erkolahti, Gunther Klosinski, Mihoko Oba, Satomi Murase, Takashi Murakami, Jiro Takai, Hitoshi Kaneko, Shuji Honjo, Katrina Rickards, Annhild Weber, Michael Karle, Alain Lazartigues, Pascale Planche, Eric Lemonnier, Mani Pavuluri, Lindsay Schenkel, Ryan Shaw, John Sweeny, Giancarlo Rigon, Stefano Costa, Alessandra Mancaruso, Roberta Mansi, Daniele Giovanni Poggioli, Simona Chiodo, Maja Radobuljac, Urban Groleger, Nada Ovsenik, Martina Tomori, Barbara Haas, Susanne Denoix, Franz Kimmig, Marc Weinhardt, Günter Schmitz, Berit Filschke, Conny Fliegauf, Ji-Hae Kim, Maya Krischer, Michael H. Stone, Kathrin Sevecke, Manfred Doepfner, Cornelia König, Dörte Grasmann, Michael Schlander, Stephen Ralston, R. Rodrigues Pereira, W. Brussel, L. Vlasveld, H. G. Tuynman-Qua, M. J. Lorenzo, R. Tauscher-Wisniewski, Stefano Palazzi, Ettore Guaia, Artur Kolakowski, Agnieszka Pisula, Timothy Wilens, Tobias Banaschewski, Henrik Uebel, Björn Albrecht, Monika Robatzek, Kristen Migliaccio-Walle, Jaime Caro, Albert J. Allen, R. Bart Sangal, Judith Owens, Douglas Kelsey, Virginia Sutton, Kory Schuh, Aliye Tugba Bahadir, Zeynep Yaman, Ayse Rodopman Arman, Kemal Kuscu, Yanki Yazgan, Meral Berkem, Peter Feldman, Milton Denai, Alexander Simpson, Christopher Kratochvil, Jeffrey Newcorn, Joseph Biederman, Douglas Gelowitz, Christine Thomason, Haitao Gao, Patricia Bijttebier, Steff Decoene, Pia Niklaus, Nils Duits, Ulrich Auer, Kathleen Schnoor, Detlef Schläfke, Füsun Çuhadaroälu Çetin, Gordon Harper, Sami Hamdan, Muhammed El-Haib, Saynur Canat, Olivier Halfon, Monique Bolognini, B. Plancherel, Olivier Phan, Maurice Corcos, Jean-René Cardinaux, Pierre J. Magistretti, Blaise Pierrehumbert, Minna Koskinen, Ulf Engqvist, Matthew Allin, Larry Rifkin, Sandra Lancaster, Ayala Borghini, Laure Jaugey, Margarita Forcada-Guex, Lyne Jaunin, Carole Müller-Nix, François Ansermet, Mariada Conceicao Taborda Simoes, Luiza Nobre Lima, Mariada Luz Vale Dias, Rainer Georg Siefen, Ariel Como, Valbona Alikaj, Sonila Tomori, Flavia Capozzi, Angela Romano, Mara Roello, Francesca Piperno, Mali A. Mann, Dieter Stösser, Gottfried Barth, Alina Pimenov, Jenny Schwab, Hülya Bingöl, Rémy Barbe, Heba Elkshishy, Ana Jovanovic, Aneta Lakic, Vesna Milovanovic, Milorad Vukasinovic, Jeffrey Bridge, David Kolko, David A. Brent, Kathryn Gilson, Roslyn Montague, Ian Shochet, Cristina Maria Ribeiro Marques, Teresa Cepeda, Carolin Ligges, Marc Ligges, Ralph Huonker, Paavo Leppänen, Torni K. Guttorm, Jarmo Hämäläinen, Anne Puolakanaho, Ellen Plume, Inke R. König, Wolfgang Deimel, Markus M. Nöthen, Peter Propping, André Kleensang, Bertram Müller-Myhsok, Andreas Ziegler, Sung-Do David Hong, Xueping Gao, Xuerong Li, Soyoung Irene Lee, Eui-Jung Kim, In-Hee Cho, Ji-Hoon Kim, Se-Hyun Park, J-Wook Choi, Steffen Heger, Andreas Schreiner, Klaus Rettig, Rossella Medori, Peik Gustafsson, Kjell Hansson, Lena Eidevall, Gunilla Thernlund, Philip Heiser, A. Dempfle, Judith Smidt, Justyna Grabarkiewicz, Hans Kiefl, U. Hemminger, K. Saar, James Swanson, Nora D. Volkov, S. Gupta, L. Williams, D. Agler, M. Wasdell, S. Wigal, Silvia Martins, Silza Tramontina, Mariana Eizirik, Benedetto Vitiello, Walter Clevenger, Stephen Faraone, James McGough, James McCracken, Luis Augusto Rohde, Larry Greenhill, Michael Leary, Bo Larsson, W. Boudewijn Gunning, Jean-Marie Villat, Redmond O’Connell, Mark A. Bellgrove, Paul Dockree, Raymond Traube, Mary Braunschweig, Jacques Chabanier, Germana De Leo, Margerita Ibanez, Olivette Mikolajaks, Ida Ropstad, J. Gerald Young, Rachele Aiello, Viviana Porcari, Maria Patrizia Salatiello, Anna Lo Bue, Valentina Dell’Oglio, Rosaria Cardella, Sabrina Chifari, Anne Mari Undheim, Linyan Su, Xuerong Luo, Joanne Barton, Lioba Baying, Thomas Rellum, Emrah Duezel, Hermann Hinrichs, Christoph Bartel, Iris Linde, E. Friederichs, Mark Bangs, Helmut Remschmidt, Theodore Doreleijers, Elisabeth Rebernig, Giovanni Battista Camerini, Soraya Otero, Ana Rivas, Guadalupe Pombo, Maruke Yeghiyan, Gasparyan Kachatur, Arman Danileyan, Tord Ivarsson, Robert Valderhaug, Susanne Walitza, Christoph Wewetzer, Nikolaus Barth, F. Hahn, Fernando Asbahr, Ana Regina Castillo, Ligia Ito, Mariado Rosario Latorre, Michelle Moreira, Francisco Lotufo-Neto, Sophie Symann, Dominique Charlier, Belinda Plattner, Astrid Elisabeth Schallauer, Beat Mohler, P. Staub, Carsten Müller, Rieke Oelkers-Ax, Jochen Fischer, Uta Hermanns, Anne Nickel, Hans Volker Bolay, Miguel Cherro-Aguerre, Merete Juul Sorensen, Judith Becker Nissen, Ole Mors, Per Hove Thomsen, Anne Mari Sund, May Britt Drugli, Lars Wichstrom, Matthias Schwannauer, Emily Taylor, Rob Wrate, Matthias Martin, Jan-Olov Larsson, Henrik Larsson, Paul Lichtenstein, Andrea G. Ludolph, Felix Mottaghy, Susanne Kraemer, Dieter Claus, Bernhard Krause, Jbrg M. Fegert, Tuula Hurtig, Anna Malakhova, Katerina Maniadaki, Efthymios Kakouros, Peter Jensen, Joe Albert Garcia, Sherry Glied, Maura Crowe, E. Michael Foster, Bernard Golse, Jenny Junghanß, Aino-Maija Salin, Päivi Rytölä, and Pauliina Hiltunen

Published
2004
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39. Correlation between serum levels of interleukin-4 and alexithymia scores in healthy female subjects: preliminary findings

Author

Jean Chambry, Olivier Guilbaud, Marlène Moussa, Linnea Hjalmarsson, Maurice Corcos, Philippe Jeammet, Gérard Chaouat, Florence Curt, Gwenolé Loas, Sabrina Paterniti, Boucart, Muriel, Laboratoire de Neurosciences Fonctionnelles et Pathologies (LNFP), and Université de Lille, Droit et Santé-Centre National de la Recherche Scientifique (CNRS)

Subjects
Adult, Aging, medicine.medical_specialty, media_common.quotation_subject, Endocrinology, Diabetes and Metabolism, Statistics as Topic, Neuropsychological Tests, Hospital Anxiety and Depression Scale, Body Mass Index, Correlation, Toronto Alexithymia Scale, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Alexithymia, Reference Values, Surveys and Questionnaires, medicine, Humans, Affective Symptoms, Psychiatry, Interleukin 4, Biological Psychiatry, media_common, medicine.diagnostic_test, Depression, Endocrine and Autonomic Systems, Serum concentration, medicine.disease, 030227 psychiatry, Psychiatry and Mental health, Feeling, Linear Models, Interleukin-2, Female, Interleukin-4, Depressed mood, Psychology, 030217 neurology & neurosurgery, Clinical psychology, Interleukin-1
Abstract

Some studies suggest that inaccuracy in recognizing and describing emotional states, combined with a highly descriptive mode of expression, as in alexithymia, may influence the immune response. We therefore investigated in healthy women the relationship between alexithymia and circulating levels of IL-1, IL-2 and IL-4.Seventeen mentally and physically healthy women aged between 20 and 25 years completed psychological questionnaires to assess alexithymia (Toronto Alexithymia Scale: TAS) and depressed mood (Hospital Anxiety and Depression Scale: HAD). Serum concentrations of IL-1, IL-2 and IL-4 were measured by ELISA.We found a significant positive correlation between serum levels of IL-4 and TAS score (r = 0.55; p = 0.021) and between factor 1 of the TAS (difficulty in identifying feelings) and IL-4 (r = 0.57; p = 0.017) while serum IL-1 and IL-2 were not detected in ten and six patients, respectively. Although there was a significant correlation between age and IL-4 levels, a linear regression with BMI, age, depressed mood and TAS as independent variables showed that only alexithymia could predict significantly increased levels of IL-4.Alexithymia and difficulty in identifying feelings could be associated with increased levels of IL-4 which may result in chronic impairment of pro/anti-inflammatory cytokine balance with psychological and somatic consequences. Nevertheless, these intriguing findings would deserve replication and extension in a larger sample of subjects.

Published
2004

40. [Are anxiety disorders more frequent in subjects with eating disorders?]

Author

Nathalie, Godart, Martine, Flament, Florence, Curt, Fabienne, Perdereau, François, Lang, Jean-Luc, Venisse, Olivier, Halfon, Paul, Bizouard, Gwenele, Loas, Maurice, Corcos, Philippe, Jeammet, and Jacques, Fermanian

Subjects
Adult, Anorexia Nervosa, Adolescent, Case-Control Studies, Humans, Female, Bulimia, Middle Aged, Anxiety Disorders
Abstract

We designed a controlled study comparing referred women with an eating disorder (ED) to a matched normal control group to answer the following questions: what are the frequencies of anxiety disorders (AD) in anorexia nervosa (AN) and bulimia nervosa (BN), according to DSM-IV criteria? Are AD significantly more frequent among women with an ED than among women from the community?We assessed frequencies of six specific AD among 271 women with a current diagnosis of AN or BN and 271 controls, using the Mini International Neuropsychiatric Interview (MINI), French DSM-IV version.Seventy-one percent of both the AN and the BN subjects had a lifetime comorbidity with at least one AD, significantly more (p0.001) than the percentage of controls with an AD. Prevalence was significantly higher in the ED groups than in controls for most types of AD, and between 41.8% and 53.3% of comorbid cases had an AD preceding the onset of the ED.Evidence that AD are significantly more frequent in subjects with ED than in the community has important etiological and therapeutic implications.

Published
2003

41. Manual skill, hand skill asymmetry, and cognitive performances in young children

Author

Maria De Agostini, Joseph Lellouch, Florence Curt, Georges Dellatolas, H. Kremin, Jean Maccario, Alexia Letierce, Epidémiologie et Biostatistique, Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire d'études sur l'acquisition et la pathologie du langage chez l'enfant (LEAPLCE), Université Paris Descartes - Paris 5 (UPD5)-Centre National de la Recherche Scientifique (CNRS), Kremin, Helgard, Institut National de la Santé et de la Recherche Médicale (INSERM) - Institut National de la Santé et de la Recherche Médicale (INSERM), and Université Paris Descartes - Paris 5 (UPD5) - Centre National de la Recherche Scientifique (CNRS)

Subjects
Elementary cognitive task, Vocabulary, media_common.quotation_subject, education, [SHS.PSY]Humanities and Social Sciences/Psychology, Phonological memory, behavioral disciplines and activities, 050105 experimental psychology, Task (project management), [SHS.PSY] Humanities and Social Sciences/Psychology, manual skil, 03 medical and health sciences, 0302 clinical medicine, Arts and Humanities (miscellaneous), children, 0501 psychology and cognitive sciences, Effects of sleep deprivation on cognitive performance, Nondominant hand, 10. No inequality, cognitive performance, General Psychology, ComputingMilieux_MISCELLANEOUS, media_common, 05 social sciences, Cognition, General Medicine, Laterality, Psychology, 030217 neurology & neurosurgery, Cognitive psychology
Abstract

A total of 1022 children aged 3 to 6 years were examined in their preschools and 27% of them were followed up for 2 years. A computerised version of the peg-moving task was used repeatedly to assess hand skill of the dominant and the nondominant hand. Cognitive performance was repeatedly evaluated by tasks involving speech, vocabulary, phonological memory, and visual-spatial skills. Results showed that: (i) age, sex, and handedness effects on hand skill asymmetry generally confirmed previous reports, especially by Annett (2002); (ii) visual-spatial and vocabulary tasks were significantly related to hand skill but speech and phonological memory tasks were not, and the role of the dominant and nondominant hand were similar; (iii) overall, manual laterality indexes were only weakly associated to some cognitive abilities; (iv) early manual skill was more strongly associated to cognitive tasks than later manual skill. These results fit the assumption of a significant role of early manual behaviour in aspects of cognitive development not relying exclusively on phonology, and raise questions about cognitive development and rehabilitation of children with early occurring manual deficiencies.

Published
2003

42. Handedness scale: how many and which items?

Author

Georges Dellatolas, Joseph Lellouch, Florence Curt, and Mounir Mesbah

Subjects
education.field_of_study, Arts and Humanities (miscellaneous), Scale (ratio), Cronbach's alpha, Population, General Medicine, Set (psychology), Psychology, education, General Psychology, Reliability (statistics), Developmental psychology
Abstract

A stepwise analysis of the Cronbach Alpha Coefficient (CAC) was performed on five large samples of adults and young children, in order to choose the ''minimum'' set of items of a handedness scale which gives the maximum reliability. In adults, a handedness scale with 12 items has nearly the same or even a better CAC than other scales with more items; so, a choice of 10 to 12 items seems to be adequate. For children, a scale with eight items seems to be quite reliable but it is not impossible that a scale including more items would lead to a slight increase of CAC. The controversial usefulness of a precise assessment of the ''general handedness factor'' (the first principal component) generated by handedness questionnaires and its J-shaped distribution in the general population are discussed.

Published
1997

44. Parental hand preference and manual functional asymmetry in preschool children

Author

Florence Curt, De Agostini M, Jean Maccario, and Georges Dellatolas

Subjects
Male, Paris, Hand preference, Transport time, Child development, Functional Laterality, Developmental psychology, Child Development, Motor Skills, Child, Preschool, Normal children, Genetics, Reaction Time, Humans, Female, Overall performance, Functional asymmetry, Psychology, Genetics (clinical), Ecology, Evolution, Behavior and Systematics, Psychomotor Performance
Abstract

Hand preference and hand skill in 1150 normal children between 3 and 6 years of age and hand preference of their parents were assessed to study the effect of parental hand preference on different dimensionsl of manual asymmetry in children. Children hand skill was measured with a computerized version of the Peg Moving Task which allowed us to split the overall performance into two components, a “transport time” and a “search time.” Paternal and maternal left-handedness was significantly related to child left-handedness. Both components of hand skill asymmetry were reduced with mother's left-handedness and one component (search time) with father's left-handedness. A significant impact of parental hand preference on child hand skill asymmetry, after controlling for child hand preference, was observed. When this analysis was limited to strong right-handed children, a greater paternal effect on child hand skill emerged. These results show the usefulness of performance tasks in detecting parent-child associations concerning manual functional asymmetry.

Published
1995

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