1. Nosocomial Staphylococcus aureus meningitis as presumed complication of intravenous catheterization
- Author
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Flor T. Tecson-Tumang
- Subjects
medicine.medical_specialty ,Spinal tap ,Epidemiology ,business.industry ,Health Policy ,Public Health, Environmental and Occupational Health ,medicine.disease ,medicine.disease_cause ,film.actor ,law.invention ,Surgery ,Bloody ,Penicillin ,Infectious Diseases ,Gram staining ,law ,Staphylococcus aureus ,film ,Ampicillin ,Anesthesia ,medicine ,Gentamicin ,business ,Meningitis ,medicine.drug - Abstract
presented at the Second Annual Veterans Administration Conference on Hospital Infection Control, Minneapolis, Minn., March 31 to April 1, 1977. Reprint requests: Flor 1. Tecson-Tumang, M.D., Infectious Disease Section, Medical Service, Veterans Administration Medical Center, East Orange, NJ 07019 120 days. On the seventh hospital day, a nurse charted an observation that the patient complained ..the IV hurt my arm" and that he subsequently pulled the IV line out. On day 8, the patient was noted to be nervous and tremulous. On day 9, it was noted that he was disoriented, had neck pain on motion, and was febrile (rectal temperature as high as 104.4° F). At this point infectious disease consultation was sought. When seen by us, the patient had frank signs of meningitis. There was no evidence of phlebitis and no skin lesions were observed. No heart murmur was heard. A spinal tap revealed turbid and xanthochromic cerebrospinal fluid with a WBC count of 2800/mm3 , 98% of which were polymorphonuclear cells and 2% lymphocytes. The protein was 340.2 mg/dl and sugar 46 mg/dl (blood sugar 135 mg/dl). A Gram stain of the cerebrospinal fluid was read as negative and ampicillin, 2 gm every 4 hours, was started. However, cultures of both blood and cerebrospinal fluid the next day revealed coagulase-positive Staphylococcus aureus resistant to penicillin but sensitive to cephalothin, gentamicin, erythromycin, lincomycin, tetracycline, and methicillin. Methicillin, 2 gm IV every 4 hours, was started and ampicillin was discontinued. On the twelfth hospital day, a repeat spinal tap revealed bloody and partially clotted spinal fluid with a red blood cell (RBe) count of 405/mm3 , WBC count 3/mm3 with two polymorphonuclear cells and one lymphocyte, sugar 115 mg/ dl (blood sugar 260 mg/ dl), and protein 230 mg/dl. Staphylococcus aureus was
- Published
- 1980
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