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1. Variations in Neonatal Length of Stay of Babies Born Extremely Preterm: An International Comparison Between iNeo Networks

Author

Lui, Kei, Marshall, Peter, Schmidt, Peter, Dhawan, Anjali, Korostenski, Larissa, Travadi, Javeed Travadi, Sharp, Mary, Gill, Andy, Pillow, Jane, Stack, Jacqueline, Birch, Pita, Nothdurft, Karen, Cooke, Lucy, Casalaz, Dan, Holberton, Jim, Stewart, Alice, Downe, Lyn, Stewart, Michael, Berry, Andrew, Hunt, Rod, Morris, Peter, Paoli, Tony De, Bolisetty, Srinivas, Paradisis, Mary, Greenhalgh, Mark, Koorts, Pieter, Kuschel, Carl, Jacobs, Sue, Doyle, Lex, Craven, John, Numa, Andrew, Carlisle, Hazel, Badawi, Nadia, Popat, Himanshu, Koh, Guan, Davis, Jonathan, Luig, Melissa, Headley, Bevan, Andersen, Chad, Ng, Linda, Chambers, Georgina, Austin, Nicola, Lynn, Adrienne, Darlow, Brian, Edmonds, Liza, Mildenhall, Lindsay, Buksh, Mariam, Battin, Malcolm, Boom, Jutta van den, Richardson, Vaughan, Barker, David, Hammond, Barbara, Rajadurai, Victor Samuel, Lam, Simon, Fung, Genevieve, Shah, Prakesh S., Beltempo, Marc, Kanungo, Jaideep, Ting, Joseph, Cieslak, Zenon, Sherlock, Rebecca, Mehrem, Ayman Abou, Toye, Jennifer, Aziz, Khalid, Fajardo, Carlos, Bodani, Jaya, Strueby, Lannae, Seshia, Mary, Louis, Deepak, Alvaro, Ruben, Mukerji, Amit, Da Silva, Orlando, Adie, Mohammad, Lee, Kyong-Soon, Ng, Eugene, Lemyre, Brigitte, Daboval, Thierry, Khurshid, Faiza, Pelausa, Ermelinda, Barrington, Keith, Lapoint, Anie, Ethier, Guillaume, Drolet, Christine, Piedboeuf, Bruno, Claveau, Martine, St-Hilaire, Marie, Bertelle, Valerie, Masse, Edith, Canning, Roderick, Makary, Hala, Ojah, Cecil, Monterrosa, Luis, Emberley, Julie, Afifi, Jehier, Kajetanowicz, Andrzej, Lee, Shoo K., Metsäranta, Marjo, Lehtonen, Liisa, Tammela, Outi, Sankilampi, Ulla, Saarela, Timo, Morag, Iris, Zangen, Shmuel, Smolkin, Tatyana, Mimouni, Francis, Bader, David, Rothschild, Avi, Strauss, Zipora, Felszer, Clari, Omari, Hussam, Tov-Friedman, Smadar Even, Bar-Oz, Benjamin, Feldman, Michael, Saad, Nizar, Flidel-Rimon, Orna, Weisbrod, Meir, Lubin, Daniel, Litmanovitz, Ita, Kugelman, Amir, Shinwell, Eric, Klinger, Gil, Nijim, Yousif, Bin-Nun, Alona, Golan, Agneta, Mandel, Dror, Fleisher-Sheffer, Vered, Oron, Anat, Bakhrakh, Lev, Hattori, Satoshi, Shirai, Masaru, Ishioka, Toru, Mori, Toshihiko, Amizuka, Takasuke, Huchimukai, Toru, Yoshida, Hiroshi, Sasaki, Ayako, Shimizu, Junichi, Nakamura, Toshihiko, Maruyama, Mami, Matsumoto, Hiroshi, Hosokawa, Shinichi, Taki, Atsuko, Nakagawa, Machiko, Ko, Kyone, Uozumi, Azusa, Nakata, Setsuko, Shimazaki, Akira, Yoda, Tatsuya, Numata, Osamu, Imamura, Hiroaki, Kobayashi, Azusa, Tokuriki, Shuko, Uchida, Yasushi, Arai, Takahiro, Ito, Mitsuhiro, Ieda, Kuniko, Ono, Toshiyuki, Hayashi, Masashi, Maki, Kanemasa, Yamakawa, MieToru, Kawai, Masahiko, Fujii, Noriko, Shiomi, Kozue, Nozaki, Koji, Wada, Hiroshi, Kim, Taho, Tokunaga, Yasuyuki, Takatera, Akihiro, Oshima, Toshio, Sumida, Hiroshi, Michinomae, Yae, Kusumoto, Yoshio, Yoshimoto, Seiji, Morisawa, Takeshi, Ohashi, Tamaki, Takahashi, Yukihiro, Sugimoto, Moriharu, Ono, Noriaki, Miyagawa, Shinichiro, Saijo, Takahiko, Yamagami, Takashi, Koyano, Kosuke, Kobayashi, Shoko, Kanda, Takeshi, Sakemi, Yoshihiro, Aoki, Mikio, Iida, Koichi, Goshi, Mitsushi, Maruyama, Yuko, Avila-Alvarez, Alejandro, Fernandez-Trisac, José Luis, Pico, M<ce:sup loc='post">a</ce:sup> Luz Couce, Fernández Seara, María José, Gutiérrez, Andrés Martínez, Vizcaíno, Carolina, Iglesias, Miriam Salvador, Zaplana, Honorio Sánchez, Colomer, Belén Fernández, García López, José Enrique, Mozo, Rafael García, González Martínez, M. Teresa, Sebastián, M<ce:sup loc='post">a</ce:sup> Dolores Muro, Carbonell, Marta Balart, Barnusell, Joan Badia, Puiggròs, Mònica Domingo, Aloy, Josep Figueras, Mussons, Francesc Botet, Sanz, Israel Anquela, Galiana, Gemma Ginovart, Coroleu, W., Iriondo, Martin, Vilella, Laura Castells, Porta, Roser, Demestre, Xavier, Nadal, Silvia Martínez, de Frutos Martínez, Cristina, López Cuesta, María Jesús, Mora, Dolores Esquivel, Tardío, Joaquín Ortiz, Benavente, Isabel, Alonso, Almudena, Olmos, Ramón Aguilera, García Cabezas, Miguel A., Jiménez, M<ce:sup loc='post">a</ce:sup> Dolores Martínez, Caballero, M<ce:sup loc='post">a</ce:sup> Pilar Jaraba, Díaz, M<ce:sup loc='post">a</ce:sup> Dolores Ordoñez, Fagundo, Alberto Trujillo, Canals, Lluis Mayol, García-Muñoz Rodrigo, Fermín, Martí, Lourdes Urquía, Moreno Galdo, María Fernanda, Suazo, José Antonio Hurtado, López, Eduardo Narbona, Fernández, José Uberos, Cortajarena Altuna, Miguel A., Zuriarrain, Oihana Muga, Navarro, David Mora, Domínguez, María Teresa, Ruiz del Prado, M<ce:sup loc='post">a</ce:sup> Yolanda, Díez, Inés Esteban, Palau Benavides, María Teresa, Lapeña, Santiago, Prada, Teresa, Mir, Eduard Soler, Sánchez, Araceli Corredera, Vega, Enrique Criado, Prado, Náyade del, Fernández, Cristina, Vilaplana, Lucía Cabanillas, Pérez, Irene Cuadrado, Gómez, Luisa López, Comeche, Laura Domingo, Martín, Isabel Llana, Armengod, Carmen González, Labián, Carmen Muñoz, Muñoz, M<ce:sup loc='post">a</ce:sup> José Santos, Bravo, Dorotea Blanco, Pérez, Vicente, Fernández, M<ce:sup loc='post">a</ce:sup> Dolores Elorza, González, Celia Díaz, Segura, Susana Ares, Azorín, Manuela López, Jimenez, Ana Belén, Sánchez-Tamayo, Tomás, Moreno, Elías Tapia, González, María, Sánchez Martínez, José Enrique, Lloreda García, José María, Orayen, Concepción Goñi, González, Javier Vilas, Albo, María Suárez, Colmenero, Eva González, Gutiérrez González, Elena Pilar, Vacas del Arco, Beatriz, Fernández, Josefina Márquez, Gordillo, Laura Acosta, Asensio, Mercedes Granero, Díaz, Carmen Macías, Albújar, Mar, Jorge, Pedro Fuster, Romero, Sabina, Falero, Mónica Rivero, Escobar Izquierdo, Ana Belén, Capell, Javier Estañ, Macián, M<ce:sup loc='post">a</ce:sup> Isabel Izquierdo, Vicente, M<ce:sup loc='post">a</ce:sup> Mar Montejo, Caballero, Raquel Izquierdo, Martínez, M<ce:sup loc='post">a</ce:sup> Mercedes, Euba, Aintzane, Serna, Amaya Rodríguez, López de Heredia Goya, Juan María, Legorburu, Alberto Pérez, Amorós, Ana Gutiérrez, Marugán Isabel, Víctor Manuel, González, Natalio Hernández, Gracia, Segundo Rite, Faci, M<ce:sup loc='post">a</ce:sup> Purificación Ventura, Villagrasa, M<ce:sup loc='post">a</ce:sup> Pilar Samper, Kofron, Jiri, Brodd, Katarina Strand, Odlind, Andreas, Alberg, Lars, Arwehed, Sofia, Hafström, Ola, Kasemo, Anna, Nederman, Karin, Åhman, Lars, Ingemarsson, Fredrik, Petersson, Henrik, Thurn, Pernilla, Albinsson, Eva, Selander, Bo, Abrahamsson, Thomas, Heimdahl, Ingela, Sveinsdottir, Kristbjorg, Wejryd, Erik, Hedlund, Anna, Söderberg, Maria Katarina, Navér, Lars, Brune, Thomas, Bäckström, Jens, Robinson, Johan, Farooqi, Aijaz, Normann, Erik, Fredriksson, Magnus, Palm, Anders, Rosenqvist, Urban, Walde, Bengt, Hagman, Cecilia, Ohlin, Andreas, Florell, Rein, Smedsaas-Löfvenberg, Agneta, Adams, Mark, Meyer, Philipp, Kusche, Rachel, Schulzke, Sven, Nelle, Mathias, Wagner, Bendicht, Riedel, Thomas, Kaczala, Grégoire, Pfister, Riccardo E., Tolsa, Jean-François, Roth, Matthias, Stocker, Martin, Laubscher, Bernhard, Malzacher, Andreas, Micallef, John P., Hegi, Lukas, Bassler, Dirk, Arlettaz, Romaine, Bernet, Vera, Dani, Carlo, Fiorini, Patrizio, Ghirri, Paolo, Tomasini, Barbara, Mittal, Anita, Kefas, Jonathan, Kamalanathan, Anand, Grosdenier, Michael, Dewhurst, Christopher, Bontea, Andreea, Webb, Delyth, Garr, Ross, Hassan, Ahmed, Ambadkar, Priyadarshan, Dyke, Mark, McDevitt, Katharine, Rewitzky, Glynis, D'Amore, Angela, Kamath, P., Settle, Paul, Maddock, Natasha, Edi-Osagie, Ngozi, Zipitis, Christos, Heal, Carrie, Birch, Jacqeline, Hasib, Abdul, Soe, Aung, Abdul-Malik, Bushra, Kisat, Hamudi, Vasu, Vimal, Sivashankar, Savi, Gupta, Richa, Rawlingson, Chris, Wickham, Tim, Theron, Marice, Kendall, Giles, Gupta, Aashish, Aladangady, Narendra, Ali, Imdad, Jain, Neeraj, Mannan, Khalid, Murthy, Vadivelam, Sullivan, Caroline, Chuang, Shu-Ling, Bate, Tristan, Tyszcuzk, Lidia, Lee, Geraint, Obi, Ozioma, Chang, John, Pai, Vinay, Huddy, Charlotte, Yasin, Salim, Nicholl, Richard, Pandey, Poornima, Cusack, Jonathan, Kairamkonda, Venkatesh, Muogbo, Dominic, Harry, Liza, Surana, Pinki, Broggio, Penny, Pillay, Tilly, Deshpande, Sanjeev, Mahadevan, Moore, Alison, Bastani, Porus, Garbash, Mehdi, Lal, Mithilesh, Abu-Harb, Majd, Allwood, Alex, Selter, Michael, Munyard, Paul, Bartle, David, Paul, Siba, Whincup, Graham, Rekha, Sanghavi, Amess, Philip, Obi, Ben, Reynolds, Peter, Misra, Indranil, De Halpert, Peter, Salgia, Sanjay, Sanghavi, Rekha, Paul, Nicola, Deketelaere, Abby, Khashu, Minesh, Johnson, Mark, Groves, Charlotte, Baird, Jim, Brennan, Nick, Vamvakiti, Katia, McIntyre, John, Holman, Jennifer, Jones, Stephen, Pike, Alison, Cairns, Pamela, Eaton, Megan, Schwarz, Karin, Gibson, David, Miall, Lawrence, Krishnamurthy, Dr, Narayanan, Sankara, Seaton, Sarah E., Draper, Elizabeth S., Kusuda, Satoshi, Håkansson, Stellan, Helenius, Kjell, Reichman, Brian, Vento, Maximo, Darlow, Brian A., Rusconi, Franca, Isayama, Tetsuya, Norman, Mikael, Yang, Junmin, and Modi, Neena

Published
2021
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2. Neonatal Intensive Care Unit-Level Patent Ductus Arteriosus Treatment Rates and Outcomes in Infants Born Extremely Preterm

Author

Harrison, Adele, Synnes, Anne, Ting, Joseph, Cieslak, Zenon, Sherlock, Rebecca, Yee, Wendy, Aziz, Khalid, Toye, Jennifer, Fajardo, Carlos, Kalapesi, Zarin, Sankaran, Koravangattu, Daspal, Sibasis, Seshia, Mary, Alvaro, Ruben, Mukerji, Amit, Da Silva, Orlando, Nwaesei, Chuks, Lee, Kyong-Soon, Dunn, Michael, Lemyre, Brigitte, Dow, Kimberly, Pelausa, Ermelinda, Barrington, Keith, Drolet, Christine, Piedboeuf, Bruno, Claveau, Martine, Beltempo, Marc, Bertelle, Valerie, Masse, Edith, Canning, Roderick, Makary, Hala, Ojah, Cecil, Monterrosa, Luis, Deshpandey, Akhil, Afifi, Jehier, Kajetanowicz, Andrzej, Andersson, Sture, Tammela, Outi, Sankilampi, Ulla, Saarela, Timo, Heymann, Eli, Zangen, Shmuel, Smolkin, Tatyana, Mimouni, Francis, Bader, David, Rothschild, Avi, Strauss, Zipora, Felszer, Clari, Omari, Hussam, Tov-Friedman, Smadar Even, Bar-Oz, Benjamin, Feldman, Michael, Saad, Nizar, Flidel-Rimon, Orna, Weisbrod, Meir, Lubin, Daniel, Litmanovitz, Ita, Kugelman, Amir, Shinwell, Eric, Klinger, Gil, Nijim, Yousif, Bin-Nun, Alona, Golan, Agneta, Mandel, Dror, Fleisher-Sheffer, Vered, Kohelet, David, Bakhrakh, Lev, Hattori, Satoshi, Shirai, Masaru, Ishioka, Toru, Mori, Toshihiko, Amizuka, Takasuke, Huchimukai, Toru, Yoshida, Hiroshi, Sasaki, Ayako, Shimizu, Junichi, Nakamura, Toshihiko, Maruyama, Mami, Matsumoto, Hiroshi, Hosokawa, Shinichi, Taki, Atsuko, Nakagawa, Machiko, Ko, Kyone, Uozumi, Azusa, Nakata, Setsuko, Shimazaki, Akira, Yoda, Tatsuya, Numata, Osamu, Imamura, Hiroaki, Kobayashi, Azusa, Tokuriki, Shuko, Uchida, Yasushi, Arai, Takahiro, Ito, Mitsuhiro, Ieda, Kuniko, Ono, Toshiyuki, Hayashi, Masashi, Maki, Kanemasa, Yamakawa, Mie- Toru, Kawai, Masahiko, Fujii, Noriko, Shiomi, Kozue, Nozaki, Koji, Wada, Hiroshi, Kim, Taho, Tokunaga, Yasuyuki, Takatera, Akihiro, Oshima, Toshio, Sumida, Hiroshi, Michinomae, Yae, Kusumoto, Yoshio, Yoshimoto, Seiji, Morisawa, Takeshi, Ohashi, Tamaki, Takahashi, Yukihiro, Sugimoto, Moriharu, Ono, Noriaki, Miyagawa, Shinichiro, Saijo, Takahiko, Yamagami, Takashi, Koyano, Kosuke, Kobayashi, Shoko, Kanda, Takeshi, Sakemi, Yoshihiro, Aoki, Mikio, Iida, Koichi, Goshi, Mitsushi, Maruyama, Yuko, Kofron, Jiri, Brodd, Katarina Strand, Odlind, Andreas, Alberg, Lars, Arwehed, Sofia, Hafström, Ola, Kasemo, Anna, Nederman, Karin, Åhman, Lars, Ingemarsson, Fredrik, Petersson, Henrik, Thurn, Pernilla, Albinsson, Eva, Selander, Bo, Abrahamsson, Thomas, Heimdahl, Ingela, Sveinsdottir, Kristbjorg, Wejryd, Erik, Hedlund, Anna, Söderberg, Maria Katarina, Navér, Lars, Brune, Thomas, Bäckström, Jens, Robinson, Johan, Farooqi, Aijaz, Normann, Erik, Fredriksson, Magnus, Palm, Anders, Rosenqvist, Urban, Walde, Bengt, Hagman, Cecilia, Ohlin, Andreas, Florell, Rein, Löfvenberg, Agneta Smedsaas, Meyer, Philipp, Kusche, Rachel, Schulzke, Sven, Nelle, Mathias, Wagner, Bendicht, Riedel, Thomas, Kaczala, Grégoire, Pfister, Riccardo E., Tolsa, Jean-François, Roth, Matthias, Stocker, Martin, Laubscher, Bernhard, Malzacher, Andreas, Micallef, John P., Hegi, Lukas, Arlettaz, Romaine, Bernet, Vera, Isayama, Tetsuya, Kusuda, Satoshi, Reichman, Brian, Lee, Shoo K., Lehtonen, Liisa, Norman, Mikael, Adams, Mark, Bassler, Dirk, Helenius, Kjell, Hakansson, Stellan, Yang, Junmin, Jain, Amish, and Shah, Prakesh S.

Published
2020
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5. Rehospitalization Through Childhood and Adolescence: Association with Neonatal Morbidities in Infants of Very Low Birth Weight

Author

Heymann, Eli, Zangen, Shmuel, Smolkin, Tatyana, Mimouni, Francis, Bader, David, Rothschild, Avi, Strauss, Zipora, Felszer, Clari, Jeryes, Jamalia, Tov-Friedman, Smadar Even, Bar-Oz, Benjamin, Feldman, Michael, Saad, Nizar, Flidel-Rimon, Orna, Weisbrod, Meir, Lubin, Daniel, Litmanovitz, Ita, Kugelman, Amir, Shinwell, Eric, Klinger, Gil, Nijim, Yousif, Golan, Agneta, Mandel, Dror, Fleisher-Sheffer, Vered, Kohelet, David, Bakhrakh, Lev, Lerner-Geva, Liat, Kuint, Jacob, Chodick, Gabriel, Boyko, Valentina, Shalev, Varda, and Reichman, Brian

Published
2017
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6. Neonatal Outcomes of Very Low Birth Weight and Very Preterm Neonates: An International Comparison

Author

Badawi, Nadia, Marshall, Peter, Craven, Paul, Simmer, Karen, Stack, Jacqueline, Casalaz, Dan, Carse, Elizabeth, Cooke, Lucy, Shingde, Vijay, Cartwright, David, Hunt, Rod, Kilburn, Charles, Dargaville, Peter, Lui, Kei, Paradisis, Mary, Rieger, Ingrid, Kuschel, Carl, Numa, Andrew, Carlisle, Hazel, Koh, Guan, Andersen, Chad, Luig, Melissa, Austin, Nicola, Broadbent, Roland, Mildenhall, Lindsay, Battin, Malcolm, Bourchier, David, Richardson, Vaughan, Synnes, Anne, Rouvinez-Bouali, Nicole, Piedboeuf, Bruno, Bulleid, Barbara, Yee, Wendy, Singhal, Nalini, Harrison, Adele, Tan-Dy, Cherrie, Shivananda, Sandesh, Tan, Kenneth, James, Andrew, Seshia, Molly, Barrington, Keith, Lefebvre, Francine, McMillan, Doug, Andrews, Wayne, Kovacs, Lajos, Dow, Kimberly, Clarke, Maxine, Riley, Patricia, Shah, Prakesh, Ohlsson, Arne, Aziz, Khalid, Peliowski, Abraham, Cieslak, Zenon, Sorokan, Todd, Kalapesi, Zarin, Ninan, Abraham, Sankaran, Koravangattu, Faucher, Daniel, Cronin, Gerarda, Canning, Roderick, da Silva, Orlando, Lee, David, Ojah, Cecil, Dunn, Michael, Heymann, Eli, Zangen, Shmuel, Kushnir, Amir, Mimouni, Francis, Bader, David, Rothschild, Avi, Strauss, Zipora, Felszer, Clari, Jeryes, Jamalia, Even Tov-Friedman, Smadar, Bar-Oz, Benjamin, Feldman, Michael, Saad, Nizar, Flidel-Rimon, Orna, Weisbrod, Meir, Lubin, Daniel, Litmanovitz, Ita, Blazer, Shraga, Shinwell, Eric, Sirota, Leah, Nijim, Yousif, Golan, Agneta, Mandel, Dror, Fleisher-Sheffer, Vered, Kohelet, David, Bakhrakh, Lev, Hattori, Satoshi, Konishi, Shohei, Amizuka, Takasuke, Kasai, Takeo, Takahasi, Ritsuko, Arai, Hirokazu, Sato, Maki, Miyazono, Yayoi, Shimizu, Junichi, Suzumura, Hiroshi, Kono, Yumi, Inoue, Takahiro, Miyabayashi, Hiroshi, Sobajima, Hisanori, Ishiguro, Rika, Sato, Hiroyuki, Totsu, Satsuki, Ishii, Nozomi, Hosono, Shigeharu, Shiraishi, Mika, Miura, Humihiro, Nakao, Atsushi, Yoda, Hitoshi, Shimizu, Mitsumasa, Seki, Kazuo, Itani, Yasuhumi, Suzuki, Keiji, Nemoto, Atsushi, Nakamura, Tomohiko, Wada, Masaki, Nagayama, Yoshihisa, Numata, Osamu, Futatani, Takeshi, Ueno, Yasuhisa, Iwai, Kazuyuki, Kono, Yoshinori, Ooki, Shigeru, Nakazawa, Yusuke, Suzuki, Chizuko, Tanaka, Taihei, Bonno, Motoki, Nakamura, Kenji, Kihara, Minako, Sano, Hiroyuki, Shiraishi, Atsushi, Ohashi, Atsushi, Ichiba, Hiroyuki, Sumi, Kiyoaki, Yoshimoto, Seiji, Takahashi, Yukihiro, Okutani, Takahiro, Miura, Masumi, Kato, Fumihide, Watabe, Shinichi, Kageyama, Misao, Fukuhara, Rie, Hayashitani, Michiko, Hasegawa, Keiko, Koyano, Kosuke, Kobayashi, Shoko, Akiyoshi, Shinosuke, Nakata, Yusei, Kanda, Takeshi, Tadashi, Hisano, Kanda, Hiroshi, Nakamura, Masaki, Matsumoto, Naoko, Ochiai, Masayuki, Aoki, Mikihiro, Kawase, Akihiko, Iida, Koichi, Ishihara, Chie, Kohama, Moriyasu, Seara, M<ce:sup loc='post">a</ce:sup> José Fernández, Bermúdez, José M<ce:sup loc='post">a</ce:sup> Fraga, Martínez Gutiérrez, Andrés, Martínez Ayúcar, María Mercedes, Díaz, Carolina Vizcaíno, Quiles Durá, José Luis, González Santacruz, María, Siguile, M<ce:sup loc='post">a</ce:sup> Anne Feret, Fernández, Adela Rodríguez, Fernández Colomer, Belén, García López, Enrique, Figuera Aloy, Josep, Botet Mussons, Francesc, Anquela Sanz, Israel, Galiana, Gemma Ginovart, Moliner Calderon, Elisenda, Pujol, Antonio Natal, Vives, Alicia Mirada, Iriondo Sanz, Martín, Porta, Roser, Cogul, Eva Capdevila, Castells Vilella, Laura, Álvarez, Bruno Alonso, Montero Macarro, José María, Barrio Sacristán, Ana R., Cuesta, M<ce:sup loc='post">a</ce:sup> Jesús López, Tardío, Ortiz, Sánchez Puerta, Eugenia Valls, Benavente Fernández, Isabel, Romero, Juan Mena, Martinez Gimenez, María Dolores, Olmos, Ramón Aguilera, Segura, Ricardo Tosca, Cabañas, Juana M<ce:sup loc='post">a</ce:sup> Guzmán, Muñoz, M<ce:sup loc='post">a</ce:sup> Dolores Huertas, Trujillo, Alberto, Moltó Ripoll, Luis Fidel, Hurtado Suazo, José Antonio, Aldea Romero, Ana Elena, Grisolía, Luis Paisán, Garrido Ocana, Ana Isabel, Soblechero, Eduardo Garcia, Ruiz del Prado, M<ce:sup loc='post">a</ce:sup> Yolanda, Díez, Inés Esteba, González-Luis, Gema E., García-Muñoz Rodrigo, Fermín, Iglesias, Emilio Álvaro, Calvo, Fernando Fernandez, Solé Mir, Eduard, Martí, Jordi Garcia, Ortiz Movilla, Roberto, Vilaplana, Lucía Cabanillas, San Miguel, Marta García, Martín, Isabel Llana, Díaz, María Fernández, Pérez Rodríguez, Jesús, Salas, Sofía, Labian, Carmen Muñoz, González Armengod, Carmen, Comeche, Laura Domingo, Sánchez Tamayo, Tomás, García del Río, Manuel, Alonso Gallego, José Ángel, Lloreda Garcia, José María, González, Javier Vilas, Ocampo, Insunza, Nieves Balado, García González, Pilar, Granero Asencio, Mercedes, Sanz, Antonia López, Díaz, Carmen Macías, Ferrari Cortés, Araceli, Fuster Jorge, Pedro Amadeo, López Mendoza, Santiago, Ramírez, Sabina Romero, Font, M<ce:sup loc='post">a</ce:sup> del Mar Albújar, de Ureta Huertas, Alicia, Plana, Antonio Arroyos, Capell, Javier Estañ, Roqués, Vicente, Morcillo, F., Marín, Sara, Omaña, María Fernanda, Iturriaga, Gabriel Saitua, Kofron, Jiri, Brodd, Katarina Strand, Odlind, Andreas, Alberg, Lars, Arwehed, Sofia, Engström, Eva, Kasemo, Anna, Ekelund, Charlotte, Åhman, Lars, Ingemarsson, Fredrik, Österdahl, Laura, Thurn, Pernilla, Albinsson, Eva, Selander, Bo, Lundberg, Fredrik, Heimdahl, Ingela, Hafström, Ola, Wejryd, Erik, Kuusima-Löfbom, Johanna, Lund, Ellen-Elisabeth, Thorén, Annelie, Hallberg, Boubou, Broström, Eva Berggren, Hertzberg, Torbjörn, Stjernstedt, Björn, Robinson, Johan, Farooqi, Aijaz, Normann, Erik, Fredriksson, Magnus, Palm, Anders, Hedblom, Åsa, Sjöberg, Kenneth, Thorbjörnsson, Leif, Ohlin, Andreas, Florell, Rein, Smedsaas-Löfvenberg, Agneta, Meyer, Philipp, Anderegg, Claudia, Schulzke, Sven, Nelle, Mathias, Wagner, Bendicht, Bär, Walter, Kaczala, Grégoire, Pfister, Riccardo E., Tolsa, Jean-François, Roth, Matthias, Berger, Thomas M., Laubscher, Bernhard, Malzacher, Andreas, Micallef, John P., Hegi, Lukas, Bassler, Dirk, Arlettaz, Romaine, Bernet, Vera, Bag, Santanu, Kefas, Jonathan, Rackham, Oliver, Thirumurgan, Arumugavelu, Yoxall, Bill, McBride, Tim, Webb, Delyth, Amegavie, Laweh, Hassan, Ahmed, Ambadkar, Priyadarshan, Dyke, Mark, Babiker, Seif, Rubin, Susan, Ogilvy-Stuart, Amanda, Panasa, Nagesh, Settle, Paul, Moise, Jonathan, Edi-Osagie, Ngozi, Heal, Carrie, Birch, Jacqeline, Hasib, Abdul, Soe, Aung, Kumar, Niraj, Kisat, Hamudi, Vasu, Vimal, Lama, Meera, Gupta, Richa, Rawlingson, Chris, Wickham, Tim, Schwarz, Karin, Sommen, Van, Watkin, Sara, Gupta, Aashish, Aladangady, Narendra, Ali, Imdad, Alsford, Lesley, Mannan, Khalid, Rainer, Ebel, Wilson, Nicholas, Thomas, Mark, Mathur, Ramnik, Cruwys, Michele, Godambe, Sunit, Watts, Timothy, Kuna, Jauro, Chang, John, Filkin, Jon, Huddy, Charlotte, Shephard, Ruth, Zieba, Krzystof, Rao, Patti, Currie, Andrew, Manzoor, Azhar, Ahmed, Munir, Simmons, Phil, Nycyk, Julie, Gallagher, Andrew, Halahakoon, Chrisantha, Deshpande, Sanjeev, Mohite, Anand, Palmer, Kate, Gibson, Alan, Garbash, Mehdi, Lal, Mithilesh, Abu-Harb, Majd, McKeon-Carter, Róisín, Selter, Michael, Munyard, Paul, Lewis, Vaughan, Raman, Mala, Whincup, Graham, Mallik, Abdus, Amess, Philip, Godden, Charles, Reynolds, Peter, Misra, Indranil, Shettihalli, Naveen, De Halpert, Peter, Salgia, Sanjay, Sanghavi, Rekha, Wigfield, Ruth, Deketelaere, Abby, Khashu, Minesh, Hall, Michael, Groves, Charlotte, Brown, Nick, Brennan, Nick, Vamvakiti, Katia, Ratnayaka, Mal, Pirie, Simon, Jones, Stephen, Mannix, Paul, Harding, David, Eaton, Megan, Gibson, David, Miall, Lawrence, Shah, Prakesh S., Sjörs, Gunnar, Mirea, Lucia, Reichman, Brian, Adams, Mark, Modi, Neena, Darlow, Brian A., Kusuda, Satoshi, San Feliciano, Laura, Yang, Junmin, Håkansson, Stellan, Mori, Rintaro, Figueras-Aloy, Josep, and Lee, Shoo K.

Published
2016
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7. Differences in growth patterns and catch-up growth of small for gestational age preterm infants fed on fortified mother's own milk v. preterm formula.

Author

Hofi, Lilach, Flidel-Rimon, Orna, Hershkovich–Shporen, Calanit, Zaharoni, Hilla, and Birk, Ruth

Subjects
HUMAN growth, INFANT formulas, STATURE, INFANT development, BODY weight, ARTIFICIAL feeding, BREAST milk, ENRICHED foods, RETROSPECTIVE studies, ACQUISITION of data, INFANT nutrition, COMPARATIVE studies, MEDICAL records, QUESTIONNAIRES, CEPHALOMETRY, DESCRIPTIVE statistics, SMALL for gestational age, LONGITUDINAL method, CHILDREN
Abstract

Small for gestational age (SGA) is typically defined as birth weight < 10th percentile for age. Limited data are available regarding the growth of SGA preterm infants in relation to feeding type. We aimed to study SGA preterm infants fed fortified mother's own milk (MOM) or preterm formula (PF) on growth patterns and catch-up growth at discharge and 2-year corrected age (CA). Our retrospective cohort study included data from medical records and follow-up questionnaires about SGA preterm infants born at < 37 weeks fed on MOM (n 40) and PF (n 40). Weight, length/height and head circumference (HC) were collected at birth, discharge and at 2-year CA, and Δ z-scores were calculated. The MOM group had significantly larger negative change in weight and length z-scores between birth and discharge, and smaller positive change in HC z-score (–0·47 (sd 0·41) v. −0·25 (sd 0·36), P = 0·01; −0·63 (sd 0·75) v. −0·27 (sd 0·75), P = 0·03; 0·13 (sd 0·67) v. 0·41 (sd 0·55), P = 0·04, respectively). Almost half of the MOM-fed infants experienced poor length growth by discharge compared with 22 % of PF-fed infants (P = 0·03). By 2-year CA, both groups had similar positive change in weight and HC z-scores, but MOM-fed infants had a slower increase in height z-score (0·64 (sd 1·30) v. 1·33 (sd 1·33), P = 0·02), and only 40 % had achieved catch-up height compared with 68 % of the PF group (P = 0·02). Our study indicates that fortified MOM-fed SGA preterm infants may need extra nutritional support in the first 2 years of life to achieve height growth potential. [ABSTRACT FROM AUTHOR]

Published
2023
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9. Centers for disease control and prevention guidelines identified more neonates at risk of early-onset sepsis than the Kaiser-Permanente calculator.

Author

Hershkovich–Shporen, Calanit, Guri, Alex, Gluskina, Tatiana, Flidel‐Rimon, Orna, Hershkovich-Shporen, Calanit, and Flidel-Rimon, Orna

Subjects
NEONATAL sepsis, NEWBORN infants, SEPSIS, CALCULATORS, COHORT analysis, INFANTS, ANTIBIOTICS, RETROSPECTIVE studies, RISK assessment
Abstract

Aim: Our aim was to retrospectively compare how many cases of early-onset sepsis (EOS) would have been predicted by the the Kaiser-Permanente (KP) calculator and the United States Centers for Disease Control and Prevention (CDC) guidelines.Methods: This observational retrospective cohort study comprised 50 newborn infants with documented EOS who were born at the Kaplan Medical Centre, Israel, between 2001 and 2018. We retrospectively evaluated whether the KP calculator and the CDC recommendations would have recommended antibiotic treatment if they had been implemented within four hours of birth.Results: EOS was diagnosed in 50 of the 109 877 infants born from 34 weeks of gestation. By four hours of birth, 18 were symptomatic, five had an equivocal clinical status, and 27 were asymptomatic. The KP calculator would have recommended antibiotic treatment for 19 (38%) neonates: 18 who were symptomatic and one who was initially asymptomatic. The CDC guidelines would have recommended antibiotic treatment for 27 (54%) nenonates: those 19 plus all 5 with equivocal status and other 3 who were asymptomatic.Conclusion: Using the CDC guidelines would have identified more equivocal and asymptomatic EOS cases within four hours of birth than the KP calculator. Enhanced observation is recommended when using the KP calculator. [ABSTRACT FROM AUTHOR]

Published
2022
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11. Rehospitalization Through Childhood and Adolescence: Association with Neonatal Morbidities in Infants of Very Low Birth Weight

Author

Kuint, Jacob, Lerner-Geva, Liat, Chodick, Gabriel, Boyko, Valentina, Shalev, Varda, Reichman, Brian, Heymann, Eli, Zangen, Shmuel, Smolkin, Tatyana, Mimouni, Francis, Bader, David, Rothschild, Avi, Strauss, Zipora, Felszer, Clari, Jeryes, Jamalia, Tov-Friedman, Smadar Even, Bar-Oz, Benjamin, Feldman, Michael, Saad, Nizar, Flidel-Rimon, Orna, Weisbrod, Meir, Lubin, Daniel, Litmanovitz, Ita, Kugelman, Amir, Shinwell, Eric, Klinger, Gil, Nijim, Yousif, Golan, Agneta, Mandel, Dror, Fleisher-Sheffer, Vered, Kohelet, David, and Bakhrakh, Lev

Published
2017
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12. Third-generation cephalosporin resistant Enterobacteriaceae in neonates and young infants: impact and outcome.

Author

Guri, Alex, Flaks-Manov, Natalie, Ghilai, Adi, Hoshen, Moshe, Flidel Rimon, Orna, Ciobotaro, Pnina, and Zimhony, Oren

Abstract

Third-generation cephalosporins resistant Enterobacteriaceae (3GCR-EB) are a major threat in severely ill neonates hospitalized in Neonatal Intensive Care Units. Still, the particular impact of 3GCR-EB on outcomes in the wide neonatal population is not well-appreciated. We aimed to study the impact of 3GCR-EB on the length of hospital stay and mortality of a general population of neonates and young infants. This was a retrospective cohort study of neonates and young infants born in eight Israeli hospitals between 2009 and 2013, with a culture taken within three months after birth that tested positive for Enterobacteriaceae (EB). Data for this study were taken from centralized electronic health records included inpatient, outpatient, socio-demographic, administrative and laboratory information. The main outcomes were length of stay and mortality. The main explanatory variable was an isolation of 3GCR-EB in any bacterial culture taken from a neonate or young infant. Cultures were taken for 31,921 neonates and young infants; 2647 (8.3%) tested positive for EB and 290 (11%) tested positive for 3GCR-EB. Length of stay for those who tested positive was 2.8 times longer (95%CI: 2.70–2.91, p ˂.001) than patients who tested positive for 3GC-susceptible EB. 3GCR-EB were also associated with increased mortality (OR: 12.06, 95%CI: 4.92–32.29). Neonates with third-generation cephalosporins resistant Enterobacteriaceae had extended hospitalization and increased mortality, which was mostly significant in normal gestational weight newborns. [ABSTRACT FROM AUTHOR]

Published
2022
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14. Contributors

Author

Abu-Shaweesh, Jalal M., primary, Accornero, Veronica H., additional, Als, Heidelise, additional, Anderson, Brenna L., additional, Aranda, Jacob V., additional, Arnold, James E., additional, Arora, Sundeep, additional, Bajaj, Komal, additional, Baley, Jill E., additional, Bancalari, Eduardo H., additional, Bandstra, Emmalee S., additional, Barksdale, Edward M., additional, Bearer, Cynthia F., additional, Blickstein, Isaac, additional, Blumer, Jeffrey L., additional, Butler, Samantha, additional, Calkins, Kara, additional, Caplan, Michael S., additional, Carlo, Waldemar A., additional, Chelimsky, Gisela, additional, Chock, Valerie Y., additional, Chwals, Walter J., additional, Cohen, Alan R., additional, Cooperman, Daniel R., additional, Crombleholme, Timothy M., additional, Curtis, Mario De, additional, Vries, Linda S. de, additional, Dell, Katherine MacRae, additional, Denne, Scott, additional, Devaskar, Sherin U., additional, Fiore, Juliann Di, additional, Donn, Steven M., additional, Edwards, Morven S., additional, Edwards, William H., additional, Erenberg, Francine, additional, Fanaroff, Avroy A., additional, Fanaroff, Jonathan M., additional, Fasano, Ross, additional, Flidel-Rimon, Orna, additional, Friedman, Smadar, additional, Gerber, Susan E., additional, Goldsmith, Jay P., additional, Gonik, Bernard, additional, Gould, Jeffrey B., additional, Gressens, Pierre, additional, Gross, Susan J., additional, Gruslin, Andrée M., additional, Gupta, Balaji K., additional, Hack, Maureen, additional, Halamek, Louis P., additional, Hamvas, Aaron, additional, Hellmann, Jonathan, additional, Hintz, Susan R., additional, Hoath, Steven B., additional, Horbar, Jeffrey D., additional, Hoyt, McCallum R., additional, Hüppi, Petra S., additional, Jain, Lucky, additional, Jobe, Alan H., additional, Judge, Nancy E., additional, Kaplan, Michael, additional, Kalhan, Satish C., additional, Kapur, Reuben, additional, Karunamuni, Ganga, additional, Kaufman, Lawrence M., additional, Kennedy, Kathleen A., additional, Kennell, John H., additional, Kitterman, Joseph A., additional, Klaus, Marshall H., additional, Kliegman, Robert M., additional, Langer, Oded, additional, Lazebnik, Noam, additional, Levene, Malcolm I., additional, Lim, Foong-Yen, additional, Lissauer, Tom, additional, Lopez, Suzanne M., additional, Lotze, Timothy E., additional, Naomi Luban, L.C., additional, Luchtman-Jones, Lori, additional, Magnuson, David K., additional, Mangurten, Henry H., additional, McClary, Jacquelyn, additional, Miller, Geoffrey, additional, Miller, Marilyn T., additional, Mohamed, Mohamed W., additional, Moore, Thomas R., additional, Morley, Colin J., additional, Morrison, Stuart C., additional, Narang, Anil, additional, Narendran, Vivek, additional, Nock, Mary L., additional, Palmert, Mark R., additional, Parikh, Aditi S., additional, Parry, Robert L., additional, Phelps, Dale L., additional, Poindexter, Brenda, additional, Polin, Richard A., additional, Puppala, Bhagya L., additional, Raju, Tonse N.K., additional, Ramachandrappa, Ashwin, additional, Redline, Raymond W., additional, Rigo, Jacques, additional, Robinson, Barrett K., additional, Rose, Susan R., additional, Rothenberg, Florence, additional, Safder, Shaista, additional, Saugstad, Ola Didrik, additional, Schaefer, Katherine S., additional, Scher, Mark S., additional, Sedin, Gunnar, additional, Shah, Dinesh M., additional, Shinwell, Eric S., additional, Shulman, Rayzel M., additional, Sibley, Eric, additional, Sinha, Sunil K., additional, Sivit, Carlos J., additional, Siwik, Ernest S., additional, Sprecher, Robert C., additional, Steinhorn, Robin H., additional, Stevenson, David K., additional, Stork, Eileen K., additional, Stork, John E., additional, Pas, Arjan B. te, additional, Thompson, George H., additional, Toltzis, Philip, additional, Turbow, Robert, additional, Tyson, Jon E., additional, Hare, George F. Van, additional, Vento, Maximo, additional, Vidyasagar, Dharmapuri, additional, Vogt, Beth A., additional, Vohr, Betty, additional, Walsh, Michele C., additional, Watanabe, Michiko, additional, Wherrett, Diane K., additional, White, Robert D., additional, Wiesner, Georgia L., additional, Wikenheiser, Jamie C., additional, Wilson, David B., additional, Wilson-Costello, Deanne, additional, Wolf, Richard B., additional, Wong, Ronald J., additional, Yoder, Mervin C., additional, Young, Thomas, additional, Zahka, Kenneth G., additional, and Zinn, Arthur B., additional

Published
2011
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18. Neonatal Intensive Care Unit-Level Patent Ductus Arteriosus Treatment Rates and Outcomes in Infants Born Extremely Preterm

Author

Isayama, Tetsuya, primary, Kusuda, Satoshi, additional, Reichman, Brian, additional, Lee, Shoo K., additional, Lehtonen, Liisa, additional, Norman, Mikael, additional, Adams, Mark, additional, Bassler, Dirk, additional, Helenius, Kjell, additional, Hakansson, Stellan, additional, Yang, Junmin, additional, Jain, Amish, additional, Shah, Prakesh S., additional, Harrison, Adele, additional, Synnes, Anne, additional, Ting, Joseph, additional, Cieslak, Zenon, additional, Sherlock, Rebecca, additional, Yee, Wendy, additional, Aziz, Khalid, additional, Toye, Jennifer, additional, Fajardo, Carlos, additional, Kalapesi, Zarin, additional, Sankaran, Koravangattu, additional, Daspal, Sibasis, additional, Seshia, Mary, additional, Alvaro, Ruben, additional, Mukerji, Amit, additional, Da Silva, Orlando, additional, Nwaesei, Chuks, additional, Lee, Kyong-Soon, additional, Dunn, Michael, additional, Lemyre, Brigitte, additional, Dow, Kimberly, additional, Pelausa, Ermelinda, additional, Barrington, Keith, additional, Drolet, Christine, additional, Piedboeuf, Bruno, additional, Claveau, Martine, additional, Beltempo, Marc, additional, Bertelle, Valerie, additional, Masse, Edith, additional, Canning, Roderick, additional, Makary, Hala, additional, Ojah, Cecil, additional, Monterrosa, Luis, additional, Deshpandey, Akhil, additional, Afifi, Jehier, additional, Kajetanowicz, Andrzej, additional, Andersson, Sture, additional, Tammela, Outi, additional, Sankilampi, Ulla, additional, Saarela, Timo, additional, Heymann, Eli, additional, Zangen, Shmuel, additional, Smolkin, Tatyana, additional, Mimouni, Francis, additional, Bader, David, additional, Rothschild, Avi, additional, Strauss, Zipora, additional, Felszer, Clari, additional, Omari, Hussam, additional, Tov-Friedman, Smadar Even, additional, Bar-Oz, Benjamin, additional, Feldman, Michael, additional, Saad, Nizar, additional, Flidel-Rimon, Orna, additional, Weisbrod, Meir, additional, Lubin, Daniel, additional, Litmanovitz, Ita, additional, Kugelman, Amir, additional, Shinwell, Eric, additional, Klinger, Gil, additional, Nijim, Yousif, additional, Bin-Nun, Alona, additional, Golan, Agneta, additional, Mandel, Dror, additional, Fleisher-Sheffer, Vered, additional, Kohelet, David, additional, Bakhrakh, Lev, additional, Hattori, Satoshi, additional, Shirai, Masaru, additional, Ishioka, Toru, additional, Mori, Toshihiko, additional, Amizuka, Takasuke, additional, Huchimukai, Toru, additional, Yoshida, Hiroshi, additional, Sasaki, Ayako, additional, Shimizu, Junichi, additional, Nakamura, Toshihiko, additional, Maruyama, Mami, additional, Matsumoto, Hiroshi, additional, Hosokawa, Shinichi, additional, Taki, Atsuko, additional, Nakagawa, Machiko, additional, Ko, Kyone, additional, Uozumi, Azusa, additional, Nakata, Setsuko, additional, Shimazaki, Akira, additional, Yoda, Tatsuya, additional, Numata, Osamu, additional, Imamura, Hiroaki, additional, Kobayashi, Azusa, additional, Tokuriki, Shuko, additional, Uchida, Yasushi, additional, Arai, Takahiro, additional, Ito, Mitsuhiro, additional, Ieda, Kuniko, additional, Ono, Toshiyuki, additional, Hayashi, Masashi, additional, Maki, Kanemasa, additional, Yamakawa, Mie- Toru, additional, Kawai, Masahiko, additional, Fujii, Noriko, additional, Shiomi, Kozue, additional, Nozaki, Koji, additional, Wada, Hiroshi, additional, Kim, Taho, additional, Tokunaga, Yasuyuki, additional, Takatera, Akihiro, additional, Oshima, Toshio, additional, Sumida, Hiroshi, additional, Michinomae, Yae, additional, Kusumoto, Yoshio, additional, Yoshimoto, Seiji, additional, Morisawa, Takeshi, additional, Ohashi, Tamaki, additional, Takahashi, Yukihiro, additional, Sugimoto, Moriharu, additional, Ono, Noriaki, additional, Miyagawa, Shinichiro, additional, Saijo, Takahiko, additional, Yamagami, Takashi, additional, Koyano, Kosuke, additional, Kobayashi, Shoko, additional, Kanda, Takeshi, additional, Sakemi, Yoshihiro, additional, Aoki, Mikio, additional, Iida, Koichi, additional, Goshi, Mitsushi, additional, Maruyama, Yuko, additional, Kofron, Jiri, additional, Brodd, Katarina Strand, additional, Odlind, Andreas, additional, Alberg, Lars, additional, Arwehed, Sofia, additional, Hafström, Ola, additional, Kasemo, Anna, additional, Nederman, Karin, additional, Åhman, Lars, additional, Ingemarsson, Fredrik, additional, Petersson, Henrik, additional, Thurn, Pernilla, additional, Albinsson, Eva, additional, Selander, Bo, additional, Abrahamsson, Thomas, additional, Heimdahl, Ingela, additional, Sveinsdottir, Kristbjorg, additional, Wejryd, Erik, additional, Hedlund, Anna, additional, Söderberg, Maria Katarina, additional, Navér, Lars, additional, Brune, Thomas, additional, Bäckström, Jens, additional, Robinson, Johan, additional, Farooqi, Aijaz, additional, Normann, Erik, additional, Fredriksson, Magnus, additional, Palm, Anders, additional, Rosenqvist, Urban, additional, Walde, Bengt, additional, Hagman, Cecilia, additional, Ohlin, Andreas, additional, Florell, Rein, additional, Löfvenberg, Agneta Smedsaas, additional, Meyer, Philipp, additional, Kusche, Rachel, additional, Schulzke, Sven, additional, Nelle, Mathias, additional, Wagner, Bendicht, additional, Riedel, Thomas, additional, Kaczala, Grégoire, additional, Pfister, Riccardo E., additional, Tolsa, Jean-François, additional, Roth, Matthias, additional, Stocker, Martin, additional, Laubscher, Bernhard, additional, Malzacher, Andreas, additional, Micallef, John P., additional, Hegi, Lukas, additional, Arlettaz, Romaine, additional, and Bernet, Vera, additional

Published
2020
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19. Neonatal Outcomes in Very Preterm Infants With Severe Congenital Heart Defects: An International Cohort Study

Author

Norman, Mikael, primary, Håkansson, Stellan, additional, Kusuda, Satoshi, additional, Vento, Maximo, additional, Lehtonen, Liisa, additional, Reichman, Brian, additional, Darlow, Brian A., additional, Adams, Mark, additional, Bassler, Dirk, additional, Isayama, Tetsuya, additional, Rusconi, Franca, additional, Lee, Shoo, additional, Lui, Kei, additional, Yang, Junmin, additional, Shah, Prakesh S., additional, Marshall, Peter, additional, Schmidt, Peter, additional, Dhawan, Anjali, additional, Craven, Paul, additional, de Waal, Koert, additional, Simmer, Karen, additional, Gill, Andy, additional, Pillow, Jane, additional, Stack, Jacqueline, additional, Birch, Pita, additional, Cooke, Lucy, additional, Casalaz, Dan, additional, Holberton, Jim, additional, Stewart, Alice, additional, Downe, Lyn, additional, Stewart, Michael, additional, Bajuk, Barbara, additional, Berry, Andrew, additional, Hunt, Rod, additional, Kilburn, Charles, additional, De Paoli, Tony, additional, Bolisetty, Srinivas, additional, Paradisis, Mary, additional, Rieger, Ingrid, additional, Koorts, Pieter, additional, Kuschel, Carl, additional, Doyle, Lex, additional, Numa, Andrew, additional, Carlisle, Hazel, additional, Badawi, Nadia, additional, Loughran‐Fowlds, Alison, additional, Koh, Guan, additional, Davis, Jonathan, additional, Luig, Melissa, additional, Andersen, Chad, additional, Chambers, Georgina, additional, Austin, Nicola, additional, Lynn, Adrienne, additional, Darlow, Brian, additional, Edmonds, Liza, additional, Mildenhall, Lindsay, additional, Buksh, Mariam, additional, Battin, Malcolm, additional, van den Boom, Jutta, additional, Bourchier, David, additional, Richardson, Vaughan, additional, Dineen, Fiona, additional, Rajadurai, Victor Samuel, additional, Lam, Simon, additional, Fung, Genevieve, additional, Harrison, Adele, additional, Synnes, Anne, additional, Ting, Joseph, additional, Cieslak, Zenon, additional, Sherlock, Rebecca, additional, Yee, Wendy, additional, Aziz, Khalid, additional, Toye, Jennifer, additional, Fajardo, Carlos, additional, Kalapesi, Zarin, additional, Sankaran, Koravangattu, additional, Daspal, Sibasis, additional, Seshia, Mary, additional, Alvaro, Ruben, additional, Mukerji, Amit, additional, Da Silva, Orlando, additional, Nwaesei, Chuks, additional, Lee, Kyong‐Soon, additional, Dunn, Michael, additional, Lemyre, Brigitte, additional, Dow, Kimberly, additional, Pelausa, Ermelinda, additional, Barrington, Keith, additional, Drolet, Christine, additional, Piedboeuf, Bruno, additional, Claveau, Martine, additional, Beltempo, Marc, additional, Bertelle, Valerie, additional, Masse, Edith, additional, Canning, Roderick, additional, Makary, Hala, additional, Ojah, Cecil, additional, Monterrosa, Luis, additional, Deshpandey, Akhil, additional, Afifi, Jehier, additional, Kajetanowicz, Andrzej, additional, Lee, Shoo K., additional, Andersson, Sture, additional, Tammela, Outi, additional, Sankilampi, Ulla, additional, Saarela, Timo, additional, Heymann, Eli, additional, Zangen, Shmuel, additional, Smolkin, Tatyana, additional, Mimouni, Francis, additional, Bader, David, additional, Rothschild, Avi, additional, Strauss, Zipora, additional, Felszer, Clari, additional, Omari, Hussam, additional, Tov‐Friedman, Smadar Even, additional, Bar‐Oz, Benjamin, additional, Feldman, Michael, additional, Saad, Nizar, additional, Flidel‐Rimon, Orna, additional, Weisbrod, Meir, additional, Lubin, Daniel, additional, Litmanovitz, Ita, additional, Kugelman, Amir, additional, Shinwell, Eric, additional, Klinger, Gil, additional, Nijim, Yousif, additional, Bin‐Nun, Alona, additional, Golan, Agneta, additional, Mandel, Dror, additional, Fleisher‐Sheffer, Vered, additional, Kohelet, David, additional, Bakhrakh, Lev, additional, Hattori, Satoshi, additional, Shirai, Masaru, additional, Ishioka, Toru, additional, Mori, Toshihiko, additional, Amizuka, Takasuke, additional, Huchimukai, Toru, additional, Yoshida, Hiroshi, additional, Sasaki, Ayako, additional, Shimizu, Junichi, additional, Nakamura, Toshihiko, additional, Maruyama, Mami, additional, Matsumoto, Hiroshi, additional, Hosokawa, Shinichi, additional, Taki, Atsuko, additional, Nakagawa, Machiko, additional, Ko, Kyone, additional, Uozumi, Azusa, additional, Nakata, Setsuko, additional, Shimazaki, Akira, additional, Yoda, Tatsuya, additional, Numata, Osamu, additional, Imamura, Hiroaki, additional, Kobayashi, Azusa, additional, Tokuriki, Shuko, additional, Uchida, Yasushi, additional, Arai, Takahiro, additional, Ito, Mitsuhiro, additional, Ieda, Kuniko, additional, Ono, Toshiyuki, additional, Hayashi, Masashi, additional, Maki, Kanemasa, additional, Yamakawa, MieToru, additional, Kawai, Masahiko, additional, Fujii, Noriko, additional, Shiomi, Kozue, additional, Nozaki, Koji, additional, Wada, Hiroshi, additional, Kim, Taho, additional, Tokunaga, Yasuyuki, additional, Takatera, Akihiro, additional, Oshima, Toshio, additional, Sumida, Hiroshi, additional, Michinomae, Yae, additional, Kusumoto, Yoshio, additional, Yoshimoto, Seiji, additional, Morisawa, Takeshi, additional, Ohashi, Tamaki, additional, Takahashi, Yukihiro, additional, Sugimoto, Moriharu, additional, Ono, Noriaki, additional, Miyagawa, Shinichiro, additional, Saijo, Takahiko, additional, Yamagami, Takashi, additional, Koyano, Kosuke, additional, Kobayashi, Shoko, additional, Kanda, Takeshi, additional, Sakemi, Yoshihiro, additional, Aoki, Mikio, additional, Iida, Koichi, additional, Goshi, Mitsushi, additional, Maruyama, Yuko, additional, Avila‐Alvarez, Alejandro, additional, Fernandez‐Trisac, José Luis, additional, Pico, Mª Luz Couce, additional, Fernández Seara, María José, additional, Gutiérrez, Andrés Martínez, additional, Vizcaíno, Carolina, additional, Salvador Iglesias, Miriam, additional, Zaplana, Honorio Sánchez, additional, Fernández Colomer, Belén, additional, García López, José Enrique, additional, Mozo, Rafael García, additional, Martínez, M. Teresa González, additional, Muro Sebastián, Mª Dolores, additional, Carbonell, Marta Balart, additional, Barnusell, Joan Badia, additional, Puiggròs, Mònica Domingo, additional, Taulí, Corporacio Parc, additional, Aloy, Josep Figueras, additional, Mussons, Francesc Botet, additional, Sanz, Israel Anquela, additional, Galiana, Gemma Ginovart, additional, De La Santa, H., additional, Coroleu, W., additional, Iriondo, Martin, additional, Castells Vilella, Laura, additional, Porta, Roser, additional, Demestre, Xavier, additional, Martínez Nadal, Silvia, additional, de Frutos Martínez, Cristina, additional, López Cuesta, María Jesús, additional, Mora, Dolores Esquivel, additional, Tardío, Joaquín Ortiz, additional, Benavente, Isabel, additional, Alonso, Almudena, additional, Aguilera Olmos, Ramón, additional, García Cabezas, Miguel A., additional, Martínez Jiménez, Mª Dolores, additional, Jaraba Caballero, Mª Pilar, additional, Ordoñez Díaz, Mª Dolores, additional, Fagundo, Alberto Trujillo, additional, Canals, Lluis Mayol, additional, Rodrigo, Fermín García‐Muñoz, additional, Martí, Lourdes Urquía, additional, Galdo, María Fernanda Moreno, additional, Suazo, José Antonio Hurtado, additional, López, Eduardo Narbona, additional, Fernández, José Uberos, additional, Cortajarena Altuna, Miguel A., additional, Muga Zuriarrain, Oihana, additional, Mora Navarro, David, additional, Domínguez, María Teresa, additional, del Prado, Mª Yolanda Ruiz, additional, Díez, Inés Esteban, additional, Palau Benavides, María Teresa, additional, Lapeña, Santiago, additional, Prada, Teresa, additional, Mir, Eduard Soler, additional, Sánchez, Araceli Corredera, additional, Vega, Enrique Criado, additional, del Prado, Náyade, additional, Fernández, Cristina, additional, Vilaplana, Lucía Cabanillas, additional, Pérez, Irene Cuadrado, additional, Gómez, Luisa López, additional, Comeche, Laura Domingo, additional, Martín, Isabel Llana, additional, González Armengod, Carmen, additional, Labián, Carmen Muñoz, additional, Santos Muñoz, Mª José, additional, Bravo, Dorotea Blanco, additional, Pérez, Vicente, additional, Fernández, Mª Dolores Elorza, additional, González, Celia Díaz, additional, Segura, Susana Ares, additional, Azorín, Manuela López, additional, MD, Ana Belén Jimenez, additional, Sánchez‐Tamayo, Tomás, additional, Moreno, Elías Tapia, additional, González, María, additional, Sánchez Martínez, José Enrique, additional, Lloreda García, José María, additional, Orayen, Concepción Goñi, additional, González, Javier Vilas, additional, Albo, María Suárez, additional, Colmenero, Eva González, additional, Gutiérrez González, Elena Pilar, additional, Vacas del Arco, Beatriz, additional, Fernández, Josefina Márquez, additional, Gordillo, Laura Acosta, additional, Asensio, Mercedes Granero, additional, Díaz, Carmen Macías, additional, Albújar, Mar, additional, Fuster Jorge, Pedro, additional, Romero, Sabina, additional, Falero, Mónica Rivero, additional, Escobar Izquierdo, Ana Belén, additional, Estañ Capell, Javier, additional, Izquierdo Macián, Mª Isabel, additional, Montejo Vicente, Mª Mar, additional, Caballero, Raquel Izquierdo, additional, Martínez, Mª Mercedes, additional, Euba, Aintzane, additional, Serna, Amaya Rodríguez, additional, de Heredia Goya, Juan María López, additional, Legorburu, Alberto Pérez, additional, Amorós, Ana Gutiérrez, additional, Isabel, Víctor Manuel Marugán, additional, González, Natalio Hernández, additional, Gracia, Segundo Rite, additional, Faci, Mª Purificación Ventura, additional, Villagrasa, Mª Pilar Samper, additional, Kofron, Jiri, additional, Strand Brodd, Katarina, additional, Odlind, Andreas, additional, Alberg, Lars, additional, Arwehed, Sofia, additional, Hafström, Ola, additional, Kasemo, Anna, additional, Nederman, Karin, additional, Åhman, Lars, additional, Ingemarsson, Fredrik, additional, Petersson, Henrik, additional, Thurn, Pernilla, additional, Albinsson, Eva, additional, Selander, Bo, additional, Abrahamsson, Thomas, additional, Heimdahl, Ingela, additional, Sveinsdottir, Kristbjorg, additional, Wejryd, Erik, additional, Hedlund, Anna, additional, Söderberg, Maria Katarina, additional, Navér, Lars, additional, Brune, Thomas, additional, Bäckström, Jens, additional, Robinson, Johan, additional, Farooqi, Aijaz, additional, Normann, Erik, additional, Fredriksson, Magnus, additional, Palm, Anders, additional, Rosenqvist, Urban, additional, Walde, Bengt, additional, Hagman, Cecilia, additional, Ohlin, Andreas, additional, Florell, Rein, additional, Smedsaas‐Löfvenberg, Agneta, additional, Meyer, Philipp, additional, Kusche, Rachel, additional, Schulzke, Sven, additional, Nelle, Mathias, additional, Wagner, Bendicht, additional, Riedel, Thomas, additional, Kaczala, Grégoire, additional, Pfister, Riccardo E., additional, Tolsa, Jean‐François, additional, Roth, Matthias, additional, Stocker, Martin, additional, Laubscher, Bernhard, additional, Malzacher, Andreas, additional, Micallef, John P., additional, Hegi, Lukas, additional, Arlettaz, Romaine, additional, Bernet, Vera, additional, Dani, Carlo, additional, Fiorini, Patrizio, additional, Ghirri, Paolo, additional, and Tomasini, Barbara, additional

Published
2020
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27. Not all newborns born to mothers with clinical chorioamnionitis need to be treated.

Author

Hershkovich-Shporen, Calanit, Ujirauli, Neli, Oren, Shachar, Juster Reicher, ADA, Gadassi, Noa, Guri, Alex, and Flidel-Rimon, Orna

Subjects
CHORIOAMNIONITIS, NEWBORN infants, MOTHERS, STREPTOCOCCAL diseases, ANTIBIOTIC prophylaxis, GESTATIONAL age, ANTIBIOTICS, RETROSPECTIVE studies, FETAL diseases, SEPSIS, QUESTIONNAIRES
Abstract

Purpose: The 2010 recommendations of the Centers for Disease Control and Prevention (CDC) for prevention of perinatal group B Streptococcal Disease (GBS) is that symptomatic newborns suspect for early onset sepsis (EOS), or newborns born to mothers with clinical chorioamnionitis should receive antibiotic treatment. Our protocol was changed accordingly during 2015. We prospectively assessed the safety of the protocol and evaluated the need to treat all newborns born to mothers with clinical chorioamnionitis and retrospectively evaluated the performance of the EOS risk calculator.Methods: The study period was from May 2015 to April 2016 at the Kaplan Medical Center (KMC). Inclusion criteria were: gestational age of 35 weeks and above, newborns that were treated with antibiotic, newborn born to mothers with risk factors for EOS or with maternal clinical chorioamnionitis, or to mothers that were given intra-partum antibiotic prophylaxis (IAP).Results: In the study period, 7058 newborns were born, 1341 (19%) neonates were included according to the inclusion criteria. Six newborns had EOS (0.85 per 1000 live born). 123/1341 (9%) of the neonates were symptomatic of whom six (4.9%) had proven EOS with RR 10.9 (CI 3.5-33.39, p < .0001), NNT was 22.6. Of them, 89/1341 (6.6%) were treated for maternal clinical chorioamnionitis, two (2.25%) had proven EOS, but they were also symptomatic. The RR was 5.03 (CI 1.03-24.6 p = .045) and the NNT was 55.5. Symptomatic newborns were at an increased risk of 2.2 to have EOS compared with newborns with maternal clinical chorioamnionitis. During the study period, 201 (15%) newborns received antibiotic treatment, while if we had only used the calculator, 111 (8%) newborns would have been treated (p<.001). Only one (out of three with maternal risk factors) newborn was symptomatic during the first hour of life. Three of the mothers whose newborn developed EOS, had no risk factors so there was no need for the calculator. The calculated EOS risk at birth for the other three ranged from 0.37 to 0.67.Conclusions: We suggest that asymptomatic newborns born to mothers with clinical chorioamnionitis should not receive antibiotic treatment automatically. [ABSTRACT FROM AUTHOR]

Published
2021
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28. Antenatal corticosteroid therapy is associated with a lower risk of cystic periventricular leukomalacia.

Author

Hershkovich Shporen, Calanit, Reichman, Brian, Zaslavsky‐Paltiel, Inna, Lerner‐Geva, Liat, and Flidel‐Rimon, Orna

Subjects
INTRAVENTRICULAR hemorrhage, NEONATAL sepsis, VERY low birth weight, PERIVENTRICULAR leukomalacia, BRONCHOPULMONARY dysplasia, PREMATURE infants, CORTICOSTEROIDS
Abstract

Aim: To evaluate the association of antenatal corticosteroids (ACS) therapy on the risk for cystic periventricular leukomalacia (c‐PVL) in very low birth weight (VLBW), very preterm infants, whilst accounting for the occurrence of major neonatal morbidities; sepsis, necrotising enterocolitis, intraventricular haemorrhage and bronchopulmonary dysplasia. Methods: Population‐based observational cohort study applying data collected by the Israel national VLBW infant database from 1995–2016. Results: Cystic PVL was diagnosed in 692 (6.8%) of the 10,170 study infants. Among 7522 infants exposed to ACS, the rate of c‐PVL was 5.4%, compared to 10.7% among those not exposed (p < 0.0001). ACS was associated with significantly lower odds for c‐PVL (Odds Ratio [OR] 0.69, 95% confidence interval [CI] 0.57–0.84). In subgroup analyses, excluding infants with one or more morbidities the rates of c‐PVL ranged from 2.7% to 5.4% among infants exposed to ACS compared to 5.6% to 10.7% in those not exposed (all p < 0.0001). ACS was associated with significantly lower OR's for c‐PVL in all subgroups, ranging from 0.52 (95% CI 0.40–0.66) to 0.62 (95% CI 0.50–0.77). Conclusion: Infants exposed to ACS had a significantly lower risk of c‐PVL. Subgroup analyses excluding infants with major neonatal comorbidities showed a consistent reduction of 40%–50% in the risk for c‐PVL following ACS therapy. [ABSTRACT FROM AUTHOR]

Published
2021
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35. Early, rapidly progressive enteral nutrition promotes growth of very low birth weight (VLBW) infants.

Author

Flidel-Rimon, Orna, Raz, Moriya, Balla, Uri, Hofi, Lilach, Juster-Reicher, Ada, and Shinwell, Eric S.

Subjects
*LOW birth weight, *CALORIE, *ENTERAL feeding, *PROTEINS, *BIRTH weight, *ANALYSIS of variance, *COMPARATIVE studies, *GESTATIONAL age, *INFANTS, *INGESTION, *LONGITUDINAL method, *RESEARCH methodology, *MEDICAL cooperation, *NUTRITIONAL requirements, *QUALITY assurance, *RESEARCH, *WEIGHT gain, *EVALUATION research, *HUMAN services programs, *RETROSPECTIVE studies
Abstract

Aim: This study describes the effects of a quality improvement program to promote improved postnatal nutrition on the growth of very low birth weight (VLBW) infants.Methods: Daily data regarding nutrition and growth were collected from the medical record of VLBW infants born during 1995-2010. The infants were grouped by year of birth in order to compare infants from before, during and after the policy change. Evaluation of growth included age in days at a return to birth weight and the proportion of infants with weight below the 10th percentile at discharge.Results: The caloric and protein intake improved significantly. The age at a return to birth weight fell (p < 0.01) from 14.6 ± 5 d to 11 ± 8 d after the change. The proportion of infants with a discharge weight below the 10th percentile for corrected age fell (p < 0.01) from 72.1% to 42.1%. Data on enteral feeding showed that increased rate of enteral feeds (EF) was associated with better growth (p < 0.001).Conclusion: Increasing awareness led to increase in caloric and protein intake in VLBW infants. Aggressive EF was associated with more rapid weight gain. However, the provision of protein and calories during the first 2 weeks of life still falls short of the latest European Society of Pediatric Gastroenterology, Hepatology and Nutrition recommendations. [ABSTRACT FROM AUTHOR]

Published
2017
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38. Is there a difference in breast milk fatty acid composition of mothers of preterm and term infants?

Author

Granot, Esther, Ishay-Gigi, Keren, Malaach, Lea, and Flidel-Rimon, Orna

Subjects
ARACHIDONIC acid, DOCOSAHEXAENOIC acid, UNSATURATED fatty acids, BREAST milk, PREMATURE infants, FATTY acid analysis, COMPARATIVE studies, FATTY acids, GESTATIONAL age, INGESTION, LACTATION, RESEARCH methodology, MEDICAL cooperation, MOTHERS, DURATION of pregnancy, RESEARCH, SURVEYS, EVALUATION research
Abstract

Objective: Arachidonic acid (ARA) (c20:4 w6) and docosahexanoic acid (DHA) (c22:6 w3) are of major importance for neural maturation and retinal function in infancy. Requirements in preterm infants are increased due to accelerated growth and limited body stores. Data regarding human milk fatty acid composition after preterm and full-term delivery is inconsistent. This study compared fatty acid composition in breast milk from full-term and preterm infants. Findings were correlated with maternal dietary intake.Methods: Human milk was obtained 4-5 days after full-term delivery (20 infants) and 4-5, 10-11 and 14-15 days after preterm delivery (21 infants, of whom 6 were born before 30 weeks). For fatty acid analysis, lipids were extracted, transesterified and separated by gas liquid chromatography.Results: Total fat content was similar in the two groups. FA composition including LCPUFA and specifically ARA & DHA were similar in full-term and preterm infants and in the sub-set born before 30 weeks. In preterm infants, postnatal age did not influence LCPUFA content.Conclusions: This study did not detect any effect of gestational age or postnatal age on milk LCPUFA content. Accordingly, the increased demand for LCPUFA and specifically DHA in preterm infants need to be met by other supplementation. [ABSTRACT FROM AUTHOR]

Published
2016
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43. Comparison of hematologic indices and markers of infection in umbilical cord and neonatal blood.

Author

Rotshenker-Olshinka, Keren, Shinwell, Eric S., Juster-Reicher, Ada, Rosin, Ilya, and Flidel-Rimon, Orna

Subjects
ANTIBIOTICS, CORD blood, HEMATOLOGY, NEWBORN infants, SEPTICEMIA in children, VENOUS pressure
Abstract

Objective: Evaluation of a neonate for suspected early neonatal sepsis routinely includes blood tests such as complete blood count, C-reactive protein (CRP) and culture. In order to obviate the need for venepuncture, we prospectively compared these tests in paired samples from umbilical cord and peripheral venous blood drawn during the first hours after birth in both preterm and term infants. Methods: Paired blood samples were studied from asymptomatic neonates with risk factors for early sepsis. Data were collected on maternal and neonatal factors that may have influenced the correlation between the tests. Results: Three hundred fifty pairs of samples were studied. Significant correlation between umbilical cord and peripheral venous samples was found for white blood cell (WBC; r = 0.683) and platelets (PLT) ( r = 0.54). Correlation for hemoglobin was lower ( r = 0.36). No cases of early neonatal sepsis were detected. However, contamination rates were 12% in umbilical cord blood and 2.5% in peripheral venous blood cultures. WBC rose after birth and the 90th percentile rose from 22 500 in umbilical cord blood to 29 700 in peripheral blood. Conclusions: Screening for sepsis with umbilical cord CBC may be useful provided normal ranges are adjusted accordingly. [ABSTRACT FROM AUTHOR]

Published
2014
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46. Correlation of transcutaneous bilirubinometry (TcB) and total serum bilirubin (TsB) levels after phototherapy.

Author

Juster-Reicher, Ada, Flidel-Rimon, Orna, Rozin, Ilya, and Shinwell, Eric S.

Subjects
*SEROCONVERSION, *SERUM, *BILIRUBIN, *PHOTOTHERAPY, *JAUNDICE
Abstract

Aim: To investigate the correlation between transcutaneous bilirubinometry (TcB) and total serum bilirubin (TsB) in jaundiced infants before and after, but not during phototherapy.Methods: This study prospectively investigated the correlation between TcB and TsB in term and near term infants before and after phototherapy.Results: Overall 673 pairs of measurements (TcB and TsB) were performed on 371 infants of ≥35 weeks gestation and with birth weight above 2000 g. Of these 337 sets were from 200 infants who had not been treated with phototherapy (Group 1) and 336 measurements from 171 infants taken between 1 h and 5 d after phototherapy (Group 2). The correlation coefficient between TcB and TsB in the whole cohort was r = 0.72. The correlation was low during the first 8 h after phototherapy (r = 0.56), but thereafter the correlation returned to the range of 0.65-0.8. Using the Sobel test, no significant difference was found between the correlation coefficients at the different time periods, with the possible exception of the difference between 1 and 8 h and 9 and 16 h which was of borderline significance with a p value of 0.06.Conclusion: This study demonstrates good correlation between TcB and TsB by 8 h after phototherapy. This adds validity to community-based screening programs employing TcB measurements plotted on TsB nomograms. Such programs may contribute to prevention of tragic cases of bilirubin-induced neurologic damage. [ABSTRACT FROM AUTHOR]

Published
2015
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48. Contributors

Author

Accornero, Veronica H., Als, Heidelise, Aranda, Jacob V., Arnold, James E., Arora, Sundeep, Baley, Jill E., Bancalari, Eduardo H., Bandstra, Emmalee S., Baylis, Françoise, Bearer, Cynthia F., Bengur, A. Resai, Blickstein, Isaac, Bloom, Ronald S., Blumer, Jeffrey L., Butler, Samantha C., Caplan, Michael S., Carlo, Waldemar A., Cassidy, Suzanne B., Chelimsky, Gisela, Chwals, Walter J., Cohen, Alan R., Cooperman, Daniel R., Crombleholme, Timothy M., Dahms, William T., Davis, Ira D., Curtis, Mario De, MacRae Dell, Katherine, Denne, Scott C., DePompei, Patricia M., DeSandre, Glenn H., de Vries, Linda, Di Fiore, Juliann M., Edwards, Morven S., Erenberg, Francine, Ernst, Judith A., Fanaroff, Avroy A., Fanaroff, Jonathan M., Flidel-Rimon, Orna, Friedman, Smadar, Gerber, Susan E., Goldenberg, Robert L., Gonik, Bernard, Gould, Jeffrey B., Greenough, Anne, Gressens, Pierre, Gruenstein, Daniel H., Gruslin, Andrée, Gupta, Balaji K., Hack, Maureen, Hales, Barbara F., Hamming, Nancy Anderson, Hellmann, Jonathan, Hintz, Susan R., Hoath, Steven B., Horbar, Jeffrey D., Hoyt, McCallum R., Hudgins, Louanne, Hüppi, Petra S., Jobe, Alan H., Judge, Nancy E., Kalhan, Satish C., Kapur, Reuben, Kennedy, Kathleen A., Kennell, John H., Klaus, Marshall H., Kliegman, Robert M., Leitch, Catherine A., Lemons, James A., Lemons, Pamela K., Levene, Malcolm, Lindsay, Carol Andrea, Lissauer, Tom, Lotze, Timothy E., Luchtman-Jones, Lori, Magnuson, David K., Mangurten, Henry H., Martin, Richard J., Miller, Geoffrey, Miller, Marilyn T., Miller, Martha J., Milner, Anthony, Moore, Thomas R., Morrison, Stuart C., Narang, Anil, Narendran, Vivek, Nock, Mary L., Palmert, Mark R., Parilla, Barbara V., Parimi, Prabhu S., Parry, Robert L., Patra, Kousiki, Phelps, Dale L., Philbin, M. Kathleen, Poindexter, Brenda B., Polin, Richard A., Raju, Tonse N.K., Ramsey, Patrick S., Redline, Raymond W., Reed, Michael D., Rigo, Jacques, Rodriguez, Ricardo J., Rose, Susan R., Saugstad, Ola Didrik, Schaal, Benoist, Schaefer, Katherine S., Scher, Mark S., Schwartz, Alan L., Schwartz, Stuart, Sedin, Gunnar, Shah, Dinesh M., Shinwell, Eric S., Sibley, Eric, Sinclair, John C., Sivit, Carlos J., Siwik, Ernest S., Sprecher, Robert C., Stevenson, David K., Stork, Eileen K., Stork, John E., Thompson, George H., Toltzis, Philip, Turbow, Robert, Tyson, Jon E., Van Hare, George F., Vento, Maximo, Vidyasagar, Dharmapuri, Vogt, Beth A., Walsh, Michele C., Watanabe, Michiko, White, Robert D., Wilson, David B., Wilson-Costello, Deanne E., Wolf, Richard B., Wong, Ronald J., Yoder, Mervin C., Yudin, Mark H., Zahka, Kenneth G., and Zinn, Arthur B.

49. The red reflex examination in neonates: an efficient tool for early diagnosis of congenital ocular diseases.

Author

Eventov-Friedman S, Leiba H, Flidel-Rimon O, Juster-Reicher A, and Shinwell ES

Subjects
Cataract congenital, Cataract diagnosis, Cataract Extraction, Early Diagnosis, Eye Diseases surgery, Female, Follow-Up Studies, Humans, Infant, Newborn, Israel, Male, Predictive Value of Tests, Surveys and Questionnaires, Visual Acuity, Eye Diseases congenital, Eye Diseases diagnosis, Neonatal Screening methods, Vision Screening methods
Abstract

Background: The American Academy of Pediatrics recently published recommendations for the red reflex assessment in the newborn period to detect and treat ocular disorders as early as possible, and to prevent lifelong visual impairment and even save lives. The test is technically simple to perform, non-invasive, requires minimal equipment and can detect a variety of ocular pathologies including cataracts and retinal abnormalities. No specific national guidelines exist on this issue., Objectives: To document the implementation of red reflex examination in routine neonatal care and present the findings., Methods: Our clinical experience following inclusion of the red reflex test into the newborn physical examination in a single center was reviewed. In addition, an electronic mail questionnaire was sent to all neonatology departments in Israel regarding performance of the red reflex test., Results: During 2007-2008, five infants were identified with congenital cataracts at days 2-6 of life prior to discharge from hospital. Surgery was performed in one infant at age 2 months and all infants underwent a thorough follow-up. The incidence of congenital cataract in our center was 1:2300. Less than half the neonatology departments have endorsed the AAP recommendation and perform the red reflex test routinely., Conclusions: Abnormal red reflex test after delivery enables a rapid ophthalmologic diagnosis, intervention and close followup. We recommend that red reflex screening be performed as part of the newborn physical examination; if abnormal, an urgent ophthalmologic referral should be made.

Published
2010

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