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In March, 2019, a trackway of seven footprints was found at a riverbank outcrop of Maniototo Conglomerate Formation in the Kyeburn River, Central Otago, South Island, New Zealand. In this study, we describe this first known occurrence of moa (Dinornithiformes) footprints to be found and recovered in Te Waipounamu/South Island. Footprints of the trackway were ∼46 mm deep, 272-300 mm wide and 260-294 mm in length. An associated separate footprint was 448 mm wide and 285 mm long. Cosmogenic nuclide dating of adjacent overlying beds from the same formation establishes a mean minimum age of burial age for the tracks of 3.57 Ma (+1.62/-1.18 Ma) with a mode of 2.9 Ma, which we interpret to be Late Pliocene, with a conservative age range of Pliocene to Early Pleistocene. The trackway maker is identified as a moa from the Emeidae family, probably from the genus Pachyornis , with a mean mass of 84.61 kg that was travelling at a speed of 2.61 kmh -1 . The single adjacent footprint was made by an individual from the family Dinornithidae, most likely from the genus Dinornis with an estimated mass of 158 kg. These moa footprints represent the second earliest fossil record of moa., Competing Interests: No potential conflict of interest was reported by the author(s)., (© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.)

Aims: This study aimed to compare COVID-19 health policy and programme responses in 16 Northern and Indigenous regions in Canada. The goal was to summarise strategies used to mitigate the initial spread of the pandemic while highlighting aspects that reflect Indigenous values. Methods: A scoping review of grey literature was completed, focusing on territorial, regional health authority, and community level websites. Further media analysis was conducted to reach saturation regarding policy changes and programmes implemented to prevent transmission, improve health communication, access testing, provide health services effectively, secure borders, and provide financial assistance. Common responses were mapped on the Women's College Hospital's Wholistic Framework for Safe Wellness to identify aspects that reflected Indigenous values. This framework utilises the medicine wheel to discuss physical health (body), ceremony (spirit), community health (heart), and assessment (mind). Results: The Women's College Hospital's Wholistic Framework for Safe Wellness quadrants of the body, spirit and heart were covered by most regions via health communication efforts, adaptations to traditional practices, and continuation of care during the pandemic, respectively. It was found that 13 regions had pandemic responses adapted for Indigenous populations. Conclusions: The responses in each Northern region show that protecting each community was a priority; however, policies and programmes were developed as a kaleidoscope of what can be done quickly and evaluated later. Assessment, risk, and prevention, covered by the mind quadrant of the Women's College Hospital's Wholistic Framework for Safe Wellness, were missing in initial emergency responses. Increasing capacity for emergency management in Northern and Indigenous regions will require contingency planning that acknowledges and builds off traditional knowledge., Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Marine phytoplankton produce and scavenge Reactive Oxygen Species, to support cellular processes, while limiting damaging reactions. Some prokaryotic picophytoplankton have, however, lost all genes encoding scavenging of hydrogen peroxide. Such losses of metabolic function can only apply to Reactive Oxygen Species which potentially traverse the cell membrane outwards, before provoking damaging intracellular reactions. We hypothesized that cell radius influences which elements of Reactive Oxygen Species metabolism are partially or fully dispensable from a cell. We therefore investigated genomes and transcriptomes from diverse marine eukaryotic phytoplankton, ranging from 0.4 to 44 μm radius, to analyze the genomic allocations encoding enzymes metabolizing Reactive Oxygen Species. Superoxide has high reactivity, short lifetimes and limited membrane permeability. Genes encoding superoxide scavenging are ubiquitous across phytoplankton, but the fractional gene allocation decreased with increasing cell radius, consistent with a nearly fixed set of core genes for scavenging superoxide pools. Hydrogen peroxide has lower reactivity, longer intracellular and extracellular lifetimes and readily crosses cell membranes. Genomic allocations to both hydrogen peroxide production and scavenging decrease with increasing cell radius. Nitric Oxide has low reactivity, long intracellular and extracellular lifetimes and readily crosses cell membranes. Neither Nitric Oxide production nor scavenging genomic allocations changed with increasing cell radius. Many taxa, however, lack the genomic capacity for nitric oxide production or scavenging. The probability of presence of capacity to produce nitric oxide decreases with increasing cell size, and is influenced by flagella and colony formation. In contrast, the probability of presence of capacity to scavenge nitric oxide increases with increasing cell size, and is again influenced by flagella and colony formation., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2023 Omar et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

The linear chromatic aberration (LCA) of several combinations of polycarbonates (PCs) and poly (methyl methacrylates) (PMMAs) as singlet, hybrid (refractive/diffractive) lenses and doublets operating with wavelengths between 380 and 1600 nm - corresponding to a typical zone of interest of concentrated photovoltaics (CPV) - are compared. Those comparisons show that the maximum theoretical concentration factor for singlets is limited to about 1000 × at normal incidence and that hybrid lenses and refractive doublets present a smaller LCA increasing the concentration factor up to 5000 × and 2 × 10(6) respectively. A new achromatization equation more useful than the Abbé equation is also presented. Finally we determined the ideal position of the focal point as a function of the LCA and the geometric concentration which maximizes the flux on the solar cell.

We propose a new family of achromatic phase shifters for infrared nulling interferometry. These key optical components can be seen as optimized Fresnel rhombs, using the total internal reflection phenomenon, modulated or not. The total internal reflection indeed comes with a phase shift between the polarization components of the incident light. We propose a solution to implement this vectorial phase shift between interferometer arms to provide the destructive interference process needed to disentangle highly contrasted objects from one another. We also show that, modulating the index transition at the total internal reflection interface allows compensating for the intrinsic material dispersion in order to make the subsequent phase shift achromatic over especially broad bands. The modulation can be induced by a thin film of a well-chosen material or a subwavelength grating whose structural parameters are thoroughly optimized. We present results from theoretical simulations together with preliminary fabrication outcomes and measurements for a prototype in Zinc Selenide.

Background: Antimicrosomal (anti-M) and antithyroglobulin (anti-Tg) antibodies are commonly measured together to detect Hashimoto's thyroiditis. Since this nearly doubles the cost of testing for one antibody, we wished to determine whether significant diagnostic loss would occur if the two tests were replaced by anti-M alone., Methods: Both tests were performed in 2030 consecutive patients referred by general internists and endocrinologists., Results: With a positive result defined as either test being positive at a 1:100 dilution, anti-M was much more sensitive than anti-Tg. Anti-M was positive in 99% (823/831) of all patients with positive tests, while anti-Tg was positive in 36% (302/831). Anti-M was the only positive test in 64% of all patients with positive tests, while anti-Tg was the only positive test in 1%. With a cutoff point of 1:400 dilution, the results were similar., Conclusions: Anti-M alone appears sufficient to detect autoimmune thyroid disease at about one half the cost of routinely performing both anti-M and anti-Tg studies. The widespread practice of performing both tests increases the cost without an offsetting diagnostic gain.

This paper investigates a method of designing and producing an unusual class of compensators. Through use of these compensators one can deliver an even dose to dmax when one is irradiating a sloping contour with a single megavoltage photon field. These compensators are designed not to provide an even dose at midplane in a patient but instead to produce what may conceptually be described as an equal surface dose. (A more accurate but less descriptive term would be equal dmax dose compensator.)

Tissue compensators afford one the opportunity of producing idealized dose distributions in radiotherapy. We have developed a technique which may be used to produce fast, accurate and inexpensive compensators within a few minutes and requires minimal patient involvement. Three dimensional contour data is acquired using a moire fringe photograph taken at the time of simulation. The photograph is projected to the size needed for the actual compensator and a sketch of the compensator is made. The sketch is placed in a specially designed small portable pantographic unit and the design is traced while the unit cuts the compensator from an indexed polyethylene-lead blank which is premounted on an acrylic tray. The polyethylene-lead material proves to have an ideal combination of properties for compensator construction including relatively high density, ease of machining, good handling characteristics and low cost.