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17. Ectopic pregnancy: features at transvaginal sonography

Author

Fleischer, Arthur C., Pennell, Rebecca G., McKee, Mary S., Worrell, John A., Keefe, Bernadette, Herbert, Carl M., Hill, George A., Cartwright, Peter S., and Kepple, Donna M.

Subjects
Ultrasonics in obstetrics, Pregnancy, Ectopic -- Diagnosis, Pregnancy, Ectopic -- Evaluation, Health
Abstract

An ectopic pregnancy occurs when the embryo does not implant in the uterus. Frequently, the embryo implants and grows in one of the fallopian tubes. If the ectopic pregnancy is not discovered early and treated, the tube may rupture. Sonography is a diagnostic imaging technique that uses high frequency sound waves to produce images of soft tissues in the body, and has been used to examine women suspected of having an ectopic pregnancy. Transvaginal sonography is performed by using a sonographic probe, which is placed in the vagina. This study reports on the findings of transvaginal sonography, which were indicative of ectopic pregnancy in 50 cases. The ectopic pregnancies were subsequently confirmed by surgery. The fallopian tubes were involved in 47 of the 50 cases, and 13 tubes had ruptured. A tubal ring was seen on sonograms from 23 of the 34 tubal pregnancies in which a rupture did not occur. Embryos could be seen in 16 of the 47 tubal pregnancies. The endometrium, the tissue that lines the uterus, appeared thickened in 20 of the 50 cases. Peritoneal fluid accumulation was seen in 35 cases. For all patients, at least one sonographic abnormality was found. These results indicate that transvaginal sonography is valuable in evaluating suspected ectopic pregnancy. (Consumer Summary produced by Reliance Medical Information, Inc.)

Published
1990

19. Real-Time Ultrasound

Author

James, A. Everette, Jr., Fleischer, Arthur C., Machin, James, Partain, C. Leon, Horev, Gadi, Price, Ronald R., Reba, Richard C., editor, Goodenough, David J., editor, and Davidson, Harold F., editor

Published
1983
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24. Ultrasound Features of Rudimentary Horn Ectopic Pregnancies.

Author

Thurber, Brian W. and Fleischer, Arthur C.

Subjects
ECTOPIC pregnancy, OBSTETRICS, VESTIGIAL organs, UTERINE rupture, MATERNAL mortality
Abstract

Rudimentary horn ectopic pregnancies are uncommonly encountered in women with müllerian duct anomalies. The clinical presentation of this entity is nonspecific, giving ultrasound a critical role in making the diagnosis. Timely diagnosis and management of rudimentary horn ectopic pregnancies are pivotal in reducing the high rates of uterine rupture and maternal mortality historically associated with this condition. [ABSTRACT FROM AUTHOR]

Published
2019
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27. Parametric mapping of contrasted ovarian transvaginal sonography.

Author

Korhonen, Katrina, Moore, Ryan, Lyshchik, Andrej, Fleischer, Arthur C., Korhonen, Katrina, Moore, Ryan, Lyshchik, Andrej, and Fleischer, Arthur C.

Abstract

The purpose of this study was to assess the accuracy of parametric analysis of transvaginal contrast-enhanced ultrasound (TV-CEUS) for distinguishing benign versus malignant ovarian masses. A total of 48 ovarian masses (37 benign and 11 borderline/malignant) were examined with TV-CEUS (Definity; Lantheus, North Billerica, MA; Philips iU22; Philips Medical Systems, Bothell, WA). Parametric images were created offline with a quantification software (Bracco Suisse SA, Geneva, Switzerland) with map color scales adjusted such that abnormal hemodynamics were represented by the color red and the presence of any red color could be used to differentiate benign and malignant tumors. Using these map color scales, low values of the perfusion parameter were coded in blue, and intermediate values of the perfusion parameter were coded in yellow. Additionally, for each individual color (red, blue, or yellow), a darker shade of that color indicated a higher intensity value. Our study found that the parametric mapping method was considerably more sensitive than standard region of interest (ROI) analysis for the detection of malignant tumors but was also less specific than standard ROI analysis. Parametric mapping allows for stricter cutoff criteria, as hemodynamics are visualized on a finer scale than ROI analyses, and as such, parametric maps are a useful addition to TV-CEUS analysis by allowing ROIs to be limited to areas of the highest malignant potential.

Published
2015

29. Early Detection of Ovarian Cancer with Conventional and Contrast-Enhanced Transvaginal Sonography: Recent Advances and Potential Improvements

Author

Fleischer, Arthur C., Lyshchik, Andrej, Hirari, Makiko, Moore, Ryan D., Abramson, Richard G., and Fishman, David A.

Subjects
Article Subject
Abstract

Recently, there have been several major technical advances in the sonographic diagnosis of ovarian cancer in its early stages. These include improved assessment of tumor morphology with transvaginal sonography (TVS), and detection and characterization of tumor neovascularity with transvaginal color Doppler sonography (TV-CDS) and contrast-enhanced transvaginal sonography (CE-TVS). This paper will discuss and illustrate these improvements and describe how they enhance detection of early-stage ovarian cancer. Our initial experience with parametric mapping of CE-TVS will also be mentioned.

Published
2012
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48. Noninvasive Assessment of Tumor Vasculature Response to Radiation-Mediated, Vasculature-Targeted Therapy Using Quantified Power Doppler Sonography

Author

Kim, Dong Wook Nathan, primary, Huamani, Jessica, additional, Niermann, Kenneth J., additional, Lee, Haakil, additional, Geng, Ling, additional, Leavitt, Lauren L., additional, Baheza, Richard A., additional, Jones, Cameron C., additional, Tumkur, Shiv, additional, Yankeelov, Thomas E., additional, Fleischer, Arthur C., additional, and Hallahan, Dennis E., additional

Published
2006
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50. Phase I/Pilot Study of SU5416 (Semaxinib) in Combination With Irinotecan/Bolus 5-FU/LV (IFL) in Patients With Metastatic Colorectal Cancer

Author

Lockhart, Albert Craig, primary, Cropp, Gillian F., additional, Berlin, Jordan D., additional, Donnelly, Edwin, additional, Schumaker, Robert D., additional, Schaaf, Larry J., additional, Hande, Kenneth R., additional, Fleischer, Arthur C., additional, Hannah, Alison L., additional, and Rothenberg, Mace L., additional

Published
2006
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