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Your search keyword '"Flammer, Patrik G."' showing total 17 results
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17 results on '"Flammer, Patrik G."'

7. Ancient chicken remains reveal the origins of virulence in Marek’s disease virus.

Author

Fiddaman, Steven R., Dimopoulos, Evangelos A., Lebrasseur, Ophélie, du Plessis, Louis, Vrancken, Bram, Charlton, Sophy, Haruda, Ashleigh F., Tabbada, Kristina, Flammer, Patrik G., Dascalu, Stefan, Marković, Nemanja, Hannah Li, Franklin, Gabrielle, Symmons, Robert, Baron, Henriette, Daróczi-Szabó, László, Shaymuratova, Dilyara N., Askeyev, Igor V., Putelat, Olivier, and Sana, Maria

Published
2023
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8. The influences of microbial colonisation and germ-free status on the chicken TCRβ repertoire

Author

Dascalu, Stefan, primary, Preston, Stephen G., additional, Dixon, Robert J., additional, Flammer, Patrik G., additional, Fiddaman, Steven, additional, Boyd, Amy, additional, Sealy, Joshua E., additional, Sadeyen, Jean-Remy, additional, Kaspers, Bernd, additional, Velge, Philippe, additional, Iqbal, Munir, additional, Bonsall, Michael B., additional, and Smith, Adrian L., additional

Published
2023
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10. Reconstructing the history of helminth prevalence in the UK

Author

Ryan, Hannah, primary, Flammer, Patrik G, additional, Nicholson, Rebecca, additional, Loe, Louise, additional, Reeves, Ben, additional, Allison, Enid, additional, Guy, Christopher, additional, Doriga, Inés Lopez, additional, Waldron, Tony, additional, Walker, Don, additional, Kirchhelle, Claas, additional, Larson, Greger, additional, and Smith, Adrian L, additional

Published
2022
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12. Additional file 2 of Repertoire analysis of ���� T cells in the chicken enables functional annotation of the genomic region revealing highly variable pan-tissue TCR gamma V gene usage as well as identifying public and private repertoires

Author

Dixon, Robert, Preston, Stephen G., Dascalu, Stefan, Flammer, Patrik G., Fiddaman, Steven R., McLoughlin, Kirstie, Boyd, Amy, Volf, Jiri, Rychlik, Ivan, Bonsall, Michael B., Kaspers, Bernd, and Smith, Adrian L.

Abstract

Additional file 2: Supplementary Fig. 1. - Levels of Publicity in each TRGV Gene in PA12 White Leghorn Chickens. Supplementary Fig. 2. - Rarefaction Plots generated using iNEXT. Supplementary Fig. 3. - Variation in the Patterns of TRGV Gamma Diversity in Tissues of PA12 White Leghorn Chickens. Supplementary Fig. 4. - Diversity of TRGV Genes in different Tissues

Published
2021
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13. Additional file 1 of Repertoire analysis of ���� T cells in the chicken enables functional annotation of the genomic region revealing highly variable pan-tissue TCR gamma V gene usage as well as identifying public and private repertoires

Author

Dixon, Robert, Preston, Stephen G., Dascalu, Stefan, Flammer, Patrik G., Fiddaman, Steven R., McLoughlin, Kirstie, Boyd, Amy, Volf, Jiri, Rychlik, Ivan, Bonsall, Michael B., Kaspers, Bernd, and Smith, Adrian L.

Abstract

Additional file 1. Primers Used in this Study

Published
2021
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14. Epidemiological insights from a large-scale investigation of intestinal helminths in Medieval Europe

Author

Flammer, Patrik G., primary, Ryan, Hannah, additional, Preston, Stephen G., additional, Warren, Sylvia, additional, Přichystalová, Renáta, additional, Weiss, Rainer, additional, Palmowski, Valerie, additional, Boschert, Sonja, additional, Fellgiebel, Katarina, additional, Jasch-Boley, Isabelle, additional, Kairies, Madita-Sophie, additional, Rümmele, Ernst, additional, Rieger, Dirk, additional, Schmid, Beate, additional, Reeves, Ben, additional, Nicholson, Rebecca, additional, Loe, Louise, additional, Guy, Christopher, additional, Waldron, Tony, additional, Macháček, Jiří, additional, Wahl, Joachim, additional, Pollard, Mark, additional, Larson, Greger, additional, and Smith, Adrian L., additional

Published
2020
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15. Investigating the complex story of one ditch—A multidisciplinary study of ditch infill provides insight into the spatial organisation within the oppidum of Bibracte (Burgundy, France)

Author

Goláňová, Petra, primary, Hajnalová, Mária, additional, Lisá, Lenka, additional, Milo, Peter, additional, Petr, Libor, additional, Fránková, Markéta, additional, Kysela, Jan, additional, Flammer, Patrik G., additional, Kočárová, Romana, additional, and Barta, Peter, additional

Published
2020
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16. Supplementary Information from Molecular archaeoparasitology identifies cultural changes in the Medieval Hanseatic trading centre of Lübeck

Author

Flammer, Patrik G., Dellicour, Simon, Preston, Stephen G., Rieger, Dirk, Warren, Sylvia, Tan, Cedric K. W., Nicholson, Rebecca, Přichystalová, Renáta, Bleicher, Niels, Wahl, Joachim, Faria, Nuno R., Pybus, Oliver G., Pollard, Mark, and Smith, Adrian L.

Subjects
parasitic diseases
Abstract

Throughout history, humans have been afflicted by parasitic worms and eggs are readily detected in archaeological deposits. This study integrated parasitological and ancient DNA methods with a large sample set dating between Neolithic and Early Modern periods to explore the utility of molecular archaeoparasitology as a new approach to study the past. Molecular analyses provided unequivocal species-level parasite identification and revealed location-specific epidemiological signatures. Faecal–oral transmitted nematodes (Ascaris lumbricoides and Trichuris trichiura) were ubiquitous across time and space. By contrast, high numbers of food-associated cestodes (Diphyllobothrium latum and Taenia saginata) were restricted to medieval Lübeck. The presence of these cestodes and changes in their prevalence at approximately 1300CE indicate substantial alterations in diet or parasite availability. Trichuris trichiura ITS-1 sequences grouped into two clades; one ubiquitous and one restricted to medieval Lübeck and Bristol. The high sequence diversity of T.t.ITS-1 detected in Lübeck is consistent with its importance as a Hanseatic trading centre. Collectively, these results introduce molecular archaeoparasitology as an artefact-independent source of historical evidence.

Published
2018
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17. Intestinal helminths as a biomolecular complex in archaeological research.

Author

Flammer PG and Smith AL

Subjects
Animals, History, 15th Century, History, 16th Century, History, 17th Century, History, 18th Century, History, 19th Century, History, 20th Century, History, Ancient, History, Medieval, Humans, Intestinal Diseases, Parasitic diagnosis, Intestinal Diseases, Parasitic parasitology, Archaeology methods, DNA, Ancient analysis, Helminths genetics, Intestinal Diseases, Parasitic history
Abstract

Enteric helminths are common parasites in many parts of the world and in the past were much more widespread both geographically and socially. Many enteric helminths are relatively long-lived in the human host, often benign or of low pathogenicity while producing large numbers of environmentally resistant eggs voided in the faeces or found associated with individual remains (skeletons and mummies). The combination of helminth characters offers opportunities to the field of historical pathogen research that are quite different to that of some of the more intensively studied high impact pathogens. Historically, a wealth of studies has employed microscopic techniques to diagnose infection using the morphology of the helminth eggs. More recently, various ancient DNA (aDNA) approaches have been applied in the archaeoparasitological context and these are revolutionizing the field, allowing much more specific diagnosis as well as interrogating the epidemiology of helminths. These advances have enhanced the potential for the field to provide unique information on past populations including using diseases to consider many aspects of life (e.g. sanitation, hygiene, diet, culinary practices and other aspects of society). Here, we consider the impact of helminth archaeoparasitology and more specifically the impact and potential for application of aDNA technologies as a part of the archaeologists' toolkit. This article is part of the theme issue 'Insights into health and disease from ancient biomolecules'.

Published
2020
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