169 results on '"Flaman, Jean-Michel"'
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2. RSK3 switches cell fate: from stress-induced senescence to malignant progression
3. Removal of senescent cells reduces the viral load and attenuates pulmonary and systemic inflammation in SARS-CoV-2-infected, aged hamsters
4. Regulation of cell function and identity by cellular senescence
5. Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression
6. Benidipine calcium channel blocker promotes the death of cigarette smoke-induced senescent cells and improves lung emphysema
7. Calcium channel ITPR2 and mitochondria–ER contacts promote cellular senescence and aging
8. Loss of Pla2r1 decreases cellular senescence and age‐related alterations caused by aging and Western diets
9. Contribution of genotoxic anticancer treatments to the development of multiple primary tumours in the context of germline TP53 mutations
10. Clinical Relevance of Gene Copy Number Variation in Metastatic Clear Cell Renal Cell Carcinoma
11. PLA2R1 promotes DNA damage and inhibits spontaneous tumor formation during aging
12. Supplementary Material & figure legends from Oncogene-Induced Senescence Limits the Progression of Pancreatic Neoplasia through Production of Activin A
13. Supplementary Data from Oncogene-Induced Senescence Limits the Progression of Pancreatic Neoplasia through Production of Activin A
14. Transformed cells after senescence give rise to more severe tumor phenotypes than transformed non-senescent cells
15. Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence
16. PACAP Protects the Adolescent and Adult Mice Brain from Ethanol Toxicity and Modulates Distinct Sets of Genes Regulating Similar Networks
17. Expression of the Calcium-Binding Protein CALB1 Is Induced and Controls Intracellular Ca2+ Levels in Senescent Cells
18. NF‐κB‐dependent secretome of senescent cells can trigger neuroendocrine transdifferentiation of breast cancer cells
19. Evidence That SARS-CoV-2 Induces Lung Cell Senescence: Potential Impact on COVID-19 Lung Disease
20. Transmission of germline TP53 mutations from male carriers to female partners
21. Gradual reduction of BUBR1 protein levels results in premature sister-chromatid separation then in aneuploidy
22. New DNA polymerase from the hyperthermophilic marine archaeon Thermococcus thioreducens
23. Expression of the Calcium-Binding Protein CALB1 Is Induced and Controls Intracellular Ca 2+ Levels in Senescent Cells.
24. Inactivation of the RRB1-Pescadillo pathway involved in ribosome biogenesis induces chromosomal instability
25. Drastic Effect of Germline TP53 Missense Mutations in Li–Fraumeni Patients
26. Overexpression of B-type cyclins alters chromosomal segregation
27. Cloning, expression, and characterization of DNA polymerase I from the hyperthermophilic archaea Thermococcus fumicolans
28. Pitfalls in the use of DGV for CNV interpretation
29. Oncogene-Induced Senescence Limits the Progression of Pancreatic Neoplasia through Production of Activin A
30. Role of the LytSR Two-Component Regulatory System in Staphylococcus lugdunensis Biofilm Formation and Pathogenesis
31. Identification of human p53 mutations with differential effects on the bax and p21 promoters using functional assays in yeast
32. Detection of 11 germline inactivating TP53 mutations and absence of TP63 and HCHK2 mutations in 17 French families with Li-Fraumeni or Li-Fraumeni-like syndrome
33. The SCN9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway
34. The antioxidant N-acetylcysteine protects from lung emphysema but induces lung adenocarcinoma in mice
35. Functional analysis of the p53 protein in AIDS-related non-Hodgkin's lymphomas and polymorphic lymphoproliferations
36. SELECTIVE DETECTION OF INACTIVATING MUTATIONS OF THE TUMOR SUPPRESSOR GENE p53 IN BLADDER TUMORS
37. P53 MUTATIONS IN BLADDER TUMORS INACTIVATE THE TRANSACTIVATION OF THE P21 AND BAX GENES, AND HAVE A PREDICTIVE VALUE FOR THE CLINICAL OUTCOME AFTER BACILLUS CALMETTE-GUERIN THERAPY
38. Germline TP53 mutations result into a constitutive defect of p53 DNA binding and transcriptional response to DNA damage
39. A genome-wide study reveals rare CNVs exclusive to extreme phenotypes of Alzheimer disease
40. Revisiting Li-Fraumeni Syndrome From TP53 Mutation Carriers
41. Transmission of germlineTP53mutations from male carriers to female partners
42. Chromosomal Instability but Lack of Transformation in Human Myoblast Preparations
43. PACAP Protects the Adolescent and Adult Mice Brain from Ethanol Toxicity and Modulates Distinct Sets of Genes Regulating Similar Networks.
44. Germline copy number variation of genes involved in chromatin remodelling in families suggestive of Li-Fraumeni syndrome with brain tumours
45. Drastic Effect of GermlineTP53Missense Mutations in Li-Fraumeni Patients
46. A Simple Method for the Routine Detection of Somatic Quantitative Genetic Alterations in Colorectal Cancer
47. Contribution of theBOP1 gene, located on 8q24, to colorectal tumorigenesis
48. Pescadillo, a Novel Cell Cycle Regulatory Protein Abnormally Expressed in Malignant Cells
49. FUNCTIONAL ANALYSIS OF THE TUMOR SUPPRESSOR GENE P53 IN NON-HODGKIN'S LYMPHOMAS AND ATYPICAL LYMPHOPROLIFERATIVE DISORDERS RELATED TO AIDS
50. The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease
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