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1. Cold Atoms in Space: Community Workshop Summary and Proposed Road-Map

Author

Alonso, Ivan, Alpigiani, Cristiano, Altschul, Brett, Araujo, Henrique, Arduini, Gianluigi, Arlt, Jan, Badurina, Leonardo, Balaz, Antun, Bandarupally, Satvika, Barone, Barry C Barish Michele, Barsanti, Michele, Bass, Steven, Bassi, Angelo, Battelier, Baptiste, Baynham, Charles F. A., Beaufils, Quentin, Belic, Aleksandar, Berge, Joel, Bernabeu, Jose, Bertoldi, Andrea, Bingham, Robert, Bize, Sebastien, Blas, Diego, Bongs, Kai, Bouyer, Philippe, Braitenberg, Carla, Brand, Christian, Braxmaier, Claus, Bresson, Alexandre, Buchmueller, Oliver, Budker, Dmitry, Bugalho, Luıs, Burdin, Sergey, Callegari, Luigi Cacciapuoti Simone, Calmet, Xavier, Calonico, Davide, Canuel, Benjamin, Caramete, Laurentiu-Ioan, Carraz, Olivier, Cassettari, Donatella, Chakraborty, Pratik, Chattopadhyay, Swapan, Chauhan, Upasna, Chen, Xuzong, Chen, Yu-Ao, Chiofalo, Maria Luisa, Coleman, Jonathon, Corgier, Robin, Cotter, J. P., Cruise, A. Michael, Cui, Yanou, Davies, Gavin, De Roeck, Albert, Demarteau, Marcel, Derevianko, Andrei, Di Clemente, Marco, Djordjevic, Goran S., Donadi, Sandro, Dore, Olivier, Dornan, Peter, Doser, Michael, Drougakis, Giannis, Dunningham, Jacob, Easo, Sajan, Eby, Joshua, Elertas, Gedminas, Ellis, John, Evans, David, Examilioti, Pandora, Fadeev, Pavel, Fanı, Mattia, Fassi, Farida, Fattori, Marco, Fedderke, Michael A., Felea, Daniel, Feng, Chen-Hao, Ferreras, Jorge, Flack, Robert, Flambaum, Victor V., Forsberg, Rene, Fromhold, Mark, Gaaloul, Naceur, Garraway, Barry M., Georgousi, Maria, Geraci, Andrew, Gibble, Kurt, Gibson, Valerie, Gill, Patrick, Giudice, Gian F., Goldwin, Jon, Gould, Oliver, Grachov, Oleg, Graham, Peter W., Grasso, Dario, Griffin, Paul F., Guerlin, Christine, Gundogan, Mustafa, Gupta, Ratnesh K, Haehnelt, Martin, Hanımeli, Ekim T., Hawkins, Leonie, Hees, Aurelien, Henderson, Victoria A., Herr, Waldemar, Herrmann, Sven, Hird, Thomas, Hobson, Richard, Hock, Vincent, Hogan, Jason M., Holst, Bodil, Holynski, Michael, Israelsson, Ulf, Jeglic, Peter, Jetzer, Philippe, Juzeliunas, Gediminas, Kaltenbaek, Rainer, Kamenik, Jernej F., Kehagias, Alex, Kirova, Teodora, Kiss-Toth, Marton, Koke, Sebastian, Kolkowitz, Shimon, Kornakov, Georgy, Kovachy, Tim, Krutzik, Markus, Kumar, Mukesh, Kumar, Pradeep, Lammerzahl, Claus, Landsberg, Greg, Poncin-Lafitte, Christophe Le, Leibrandt, David R., Leveque, Thomas, Lewicki, Marek, Li, Rui, Lipniacka, Anna, Liu, Christian Lisdat Mia, Lopez-Gonzalez, J. L., Loriani, Sina, Louko, Jorma, Luciano, Giuseppe Gaetano, Lundblad, Nathan, Maddox, Steve, Mahmoud, M. A., Maleknejad, Azadeh, March-Russell, John, Massonnet, Didier, McCabe, Christopher, Meister, Matthias, Meznarsic, Tadej, Micalizio, Salvatore, Migliaccio, Federica, Millington, Peter, Milosevic, Milan, Mitchell, Jeremiah, Morley, Gavin W., Muller, Jurgen, Murphy, Eamonn, Mustecaplıoglu, Ozgur E., OShea, Val, Oi, Daniel K. L., Olson, Judith, Pal, Debapriya, Papazoglou, Dimitris G., Pasatembou, Elizabeth, Paternostro, Mauro, Pawlowski, Krzysztof, Pelucchi, Emanuele, Santos, Franck Pereira dos, Peters, Achim, Pikovski, Igor, Pilaftsis, Apostolos, Pinto, Alexandra, Prevedelli, Marco, Puthiya-Veettil, Vishnupriya, Quenby, John, Rafelski, Johann, Rasel, Ernst M., Ravensbergen, Cornelis, Reguzzoni, Mirko, Richaud, Andrea, Riou, Isabelle, Rothacher, Markus, Roura, Albert, Ruschhaupt, Andreas, Sabulsky, Dylan O., Safronova, Marianna, Saltas, Ippocratis D., Salvi, Leonardo, Sameed, Muhammed, Saurabh, Pandey, Schaffer, Stefan, Schiller, Stephan, Schilling, Manuel, Schkolnik, Vladimir, Schlippert, Dennis, Schmidt, Piet O., Schnatz, Harald, Schneider, Jean, Schneider, Ulrich, Schreck, Florian, Schubert, Christian, Shayeghi, Armin, Sherrill, Nathaniel, Shipsey, Ian, Signorini, Carla, Singh, Rajeev, Singh, Yeshpal, Skordis, Constantinos, Smerzi, Augusto, Sopuerta, Carlos F., Sorrentino, Fiodor, Sphicas, Paraskevas, Stadnik, Yevgeny V., Stefanescu, Petruta, Tarallo, Marco G., Tentindo, Silvia, Tino, Guglielmo M., Tinsley, Jonathan N., Tornatore, Vincenza, Treutlein, Philipp, Trombettoni, Andrea, Tsai, Yu-Dai, Tuckey, Philip, Uchida, Melissa A, Valenzuela, Tristan, Bossche, Mathias Van Den, Vaskonen, Ville, Verma, Gunjan, Vetrano, Flavio, Vogt, Christian, von Klitzing, Wolf, Waller, Pierre, Walser, Reinhold, Williams, Eric Wille Jason, Windpassinger, Patrick, Wittrock, Ulric, Wolf, Peter, Woltmann, Marian, Worner, Lisa, Xuereb, Andre, Yahia, Mohamed, Yazgan, Efe, Yu, Nan, Zahzam, Nassim, Cruzeiro, Emmanuel Zambrini, Zhan, Mingsheng, Zou, Xinhao, Zupan, Jure, and Zupanic, Erik

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, General Relativity and Quantum Cosmology, High Energy Physics - Experiment, High Energy Physics - Phenomenology, Physics - Atomic Physics
Abstract

We summarize the discussions at a virtual Community Workshop on Cold Atoms in Space concerning the status of cold atom technologies, the prospective scientific and societal opportunities offered by their deployment in space, and the developments needed before cold atoms could be operated in space. The cold atom technologies discussed include atomic clocks, quantum gravimeters and accelerometers, and atom interferometers. Prospective applications include metrology, geodesy and measurement of terrestrial mass change due to, e.g., climate change, and fundamental science experiments such as tests of the equivalence principle, searches for dark matter, measurements of gravitational waves and tests of quantum mechanics. We review the current status of cold atom technologies and outline the requirements for their space qualification, including the development paths and the corresponding technical milestones, and identifying possible pathfinder missions to pave the way for missions to exploit the full potential of cold atoms in space. Finally, we present a first draft of a possible road-map for achieving these goals, that we propose for discussion by the interested cold atom, Earth Observation, fundamental physics and other prospective scientific user communities, together with ESA and national space and research funding agencies., Comment: Summary of the Community Workshop on Cold Atoms in Space and corresponding Road-map: https://indico.cern.ch/event/1064855/

Published
2022
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2. AEDGE: Atomic Experiment for Dark Matter and Gravity Exploration in Space

Author

El-Neaj, Yousef Abou, Alpigiani, Cristiano, Amairi-Pyka, Sana, Araujo, Henrique, Balaz, Antun, Bassi, Angelo, Bathe-Peters, Lars, Battelier, Baptiste, Belic, Aleksandar, Bentine, Elliot, Bernabeu, Jose, Bertoldi, Andrea, Bingham, Robert, Blas, Diego, Bolpasi, Vasiliki, Bongs, Kai, Bose, Sougato, Bouyer, Philippe, Bowcock, Themis, Bowden, William, Buchmueller, Oliver, Burrage, Clare, Calmet, Xavier, Canuel, Benjamin, Caramete, Laurentiu-Ioan, Carroll, Andrew, Cella, Giancarlo, Charmandaris, Vassilis, Chattopadhyay, Swapan, Chen, Xuzong, Chiofalo, Maria Luisa, Coleman, Jonathon, Cotter, Joseph, Cui, Yanou, Derevianko, Andrei, De Roeck, Albert, Djordjevic, Goran, Dornan, Peter, Doser, Michael, Drougkakis, Ioannis, Dunningham, Jacob, Dutan, Ioana, Easo, Sajan, Elertas, Gedminas, Ellis, John, Sawy, Mai El, Fassi, Farida, Felea, Daniel, Feng, Chen-Hao, Flack, Robert, Foot, Chris, Fuentes, Ivette, Gaaloul, Naceur, Gauguet, Alexandre, Geiger, Remi, Gibson, Valerie, Giudice, Gian, Goldwin, Jon, Grachov, Oleg, Graham, Peter W., Grasso, Dario, van der Grinten, Maurits, Gundogan, Mustafa, Haehnelt, Martin G., Harte, Tiffany, Hees, Aurelien, Hobson, Richard, Holst, Bodil, Hogan, Jason, Kasevich, Mark, Kavanagh, Bradley J., von Klitzing, Wolf, Kovachy, Tim, Krikler, Benjamin, Krutzik, Markus, Lewicki, Marek, Lien, Yu-Hung, Liu, Miaoyuan, Luciano, Giuseppe Gaetano, Magnon, Alain, Mahmoud, Mohammed, Malik, Sarah, McCabe, Christopher, Mitchell, Jeremiah, Pahl, Julia, Pal, Debapriya, Pandey, Saurabh, Papazoglou, Dimitris, Paternostro, Mauro, Penning, Bjoern, Peters, Achim, Prevedelli, Marco, Puthiya-Veettil, Vishnupriya, Quenby, John, Rasel, Ernst, Ravenhall, Sean, Sfar, Haifa Rejeb, Ringwood, Jack, Roura, Albert, Sabulsky, Dylan, Sameed, Muhammed, Sauer, Ben, Schaffer, Stefan Alaric, Schiller, Stephan, Schkolnik, Vladimir, Schlippert, Dennis, Schubert, Christian, Shayeghi, Armin, Shipsey, Ian, Signorini, Carla, Soares-Santos, Marcelle, Sorrentino, Fiodor, Singh, Yajpal, Sumner, Timothy, Tassis, Konstantinos, Tentindo, Silvia, Tino, Guglielmo Maria, Tinsley, Jonathan N., Unwin, James, Valenzuela, Tristan, Vasilakis, Georgios, Vaskonen, Ville, Vogt, Christian, Webber-Date, Alex, Wenzlawski, Andre, Windpassinger, Patrick, Woltmann, Marian, Holynski, Michael, Yazgan, Efe, Zhan, Ming-Sheng, Zou, Xinhao, and Zupan, Jure

Subjects
General Relativity and Quantum Cosmology, Astrophysics - Instrumentation and Methods for Astrophysics, High Energy Physics - Experiment, High Energy Physics - Phenomenology, Physics - Atomic Physics
Abstract

We propose in this White Paper a concept for a space experiment using cold atoms to search for ultra-light dark matter, and to detect gravitational waves in the frequency range between the most sensitive ranges of LISA and the terrestrial LIGO/Virgo/KAGRA/INDIGO experiments. This interdisciplinary experiment, called Atomic Experiment for Dark Matter and Gravity Exploration (AEDGE), will also complement other planned searches for dark matter, and exploit synergies with other gravitational wave detectors. We give examples of the extended range of sensitivity to ultra-light dark matter offered by AEDGE, and how its gravitational-wave measurements could explore the assembly of super-massive black holes, first-order phase transitions in the early universe and cosmic strings. AEDGE will be based upon technologies now being developed for terrestrial experiments using cold atoms, and will benefit from the space experience obtained with, e.g., LISA and cold atom experiments in microgravity. This paper is based on a submission (v1) in response to the Call for White Papers for the Voyage 2050 long-term plan in the ESA Science Programme. ESA limited the number of White Paper authors to 30. However, in this version (v2) we have welcomed as supporting authors participants in the Workshop on Atomic Experiments for Dark Matter and Gravity Exploration held at CERN: ({\tt https://indico.cern.ch/event/830432/}), as well as other interested scientists, and have incorporated additional material., Comment: V2 -- added support authors

Published
2019
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3. Abstract PR015: Discovery of LY4050784 (FHD-909), a selective BRM (SMARCA2) ATPase inhibitor for the treatment of BRG1(SMARCA4) mutant cancers

Author

Lee, Janice Y., primary, Brooks, Nathan, additional, Antonakos, Brandon, additional, Perria, Bryan, additional, Langan, Candace, additional, Jones, Bonita D., additional, Flack, Robert Stephen, additional, Li, Zhifang, additional, Terry, David, additional, Wallace, Ross, additional, Bondi, Robert, additional, Sis, Gereint, additional, Baracani, Ronee, additional, McVean, Maralee, additional, Kolakowski, Gabrielle, additional, Osimboni, Dayo, additional, and Wilson, Kevin, additional

Published
2024
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5. AEDGE: Atomic Experiment for Dark Matter and Gravity Exploration in Space

Author

El-Neaj, Yousef Abou, Alpigiani, Cristiano, Amairi-Pyka, Sana, Araújo, Henrique, Balaž, Antun, Bassi, Angelo, Bathe-Peters, Lars, Battelier, Baptiste, Belić, Aleksandar, Bentine, Elliot, Bernabeu, José, Bertoldi, Andrea, Bingham, Robert, Blas, Diego, Bolpasi, Vasiliki, Bongs, Kai, Bose, Sougato, Bouyer, Philippe, Bowcock, Themis, Bowden, William, Buchmueller, Oliver, Burrage, Clare, Calmet, Xavier, Canuel, Benjamin, Caramete, Laurentiu-Ioan, Carroll, Andrew, Cella, Giancarlo, Charmandaris, Vassilis, Chattopadhyay, Swapan, Chen, Xuzong, Chiofalo, Maria Luisa, Coleman, Jonathon, Cotter, Joseph, Cui, Yanou, Derevianko, Andrei, De Roeck, Albert, Djordjevic, Goran S., Dornan, Peter, Doser, Michael, Drougkakis, Ioannis, Dunningham, Jacob, Dutan, Ioana, Easo, Sajan, Elertas, Gedminas, Ellis, John, El Sawy, Mai, Fassi, Farida, Felea, Daniel, Feng, Chen-Hao, Flack, Robert, Foot, Chris, Fuentes, Ivette, Gaaloul, Naceur, Gauguet, Alexandre, Geiger, Remi, Gibson, Valerie, Giudice, Gian, Goldwin, Jon, Grachov, Oleg, Graham, Peter W., Grasso, Dario, van der Grinten, Maurits, Gündogan, Mustafa, Haehnelt, Martin G., Harte, Tiffany, Hees, Aurélien, Hobson, Richard, Hogan, Jason, Holst, Bodil, Holynski, Michael, Kasevich, Mark, Kavanagh, Bradley J., von Klitzing, Wolf, Kovachy, Tim, Krikler, Benjamin, Krutzik, Markus, Lewicki, Marek, Lien, Yu-Hung, Liu, Miaoyuan, Luciano, Giuseppe Gaetano, Magnon, Alain, Mahmoud, Mohammed Attia, Malik, Sarah, McCabe, Christopher, Mitchell, Jeremiah, Pahl, Julia, Pal, Debapriya, Pandey, Saurabh, Papazoglou, Dimitris, Paternostro, Mauro, Penning, Bjoern, Peters, Achim, Prevedelli, Marco, Puthiya-Veettil, Vishnupriya, Quenby, John, Rasel, Ernst, Ravenhall, Sean, Ringwood, Jack, Roura, Albert, Sabulsky, Dylan, Sameed, Muhammed, Sauer, Ben, Schäffer, Stefan Alaric, Schiller, Stephan, Schkolnik, Vladimir, Schlippert, Dennis, Schubert, Christian, Sfar, Haifa Rejeb, Shayeghi, Armin, Shipsey, Ian, Signorini, Carla, Singh, Yeshpal, Soares-Santos, Marcelle, Sorrentino, Fiodor, Sumner, Timothy, Tassis, Konstantinos, Tentindo, Silvia, Tino, Guglielmo Maria, Tinsley, Jonathan N., Unwin, James, Valenzuela, Tristan, Vasilakis, Georgios, Vaskonen, Ville, Vogt, Christian, Webber-Date, Alex, Wenzlawski, André, Windpassinger, Patrick, Woltmann, Marian, Yazgan, Efe, Zhan, Ming-Sheng, Zou, Xinhao, and Zupan, Jure

Published
2020
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6. Supplementary Methods from ERK Inhibitor LY3214996 Targets ERK Pathway–Driven Cancers: A Therapeutic Approach Toward Precision Medicine

Author

Bhagwat, Shripad V., primary, McMillen, William T., primary, Cai, Shufen, primary, Zhao, Baohui, primary, Whitesell, Matthew, primary, Shen, Weihua, primary, Kindler, Lisa, primary, Flack, Robert S., primary, Wu, Wenjuan, primary, Anderson, Bryan, primary, Zhai, Yan, primary, Yuan, Xiu-Juan, primary, Pogue, Meghann, primary, Van Horn, Robert D., primary, Rao, Xi, primary, McCann, Denis, primary, Dropsey, Andrew J., primary, Manro, Jason, primary, Walgren, Jennie, primary, Yuen, Eunice, primary, Rodriguez, Michael J., primary, Plowman, Gregory D., primary, Tiu, Ramon V., primary, Joseph, Sajan, primary, and Peng, Sheng-Bin, primary

Published
2023
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7. Data from ERK Inhibitor LY3214996 Targets ERK Pathway–Driven Cancers: A Therapeutic Approach Toward Precision Medicine

Author

Bhagwat, Shripad V., primary, McMillen, William T., primary, Cai, Shufen, primary, Zhao, Baohui, primary, Whitesell, Matthew, primary, Shen, Weihua, primary, Kindler, Lisa, primary, Flack, Robert S., primary, Wu, Wenjuan, primary, Anderson, Bryan, primary, Zhai, Yan, primary, Yuan, Xiu-Juan, primary, Pogue, Meghann, primary, Van Horn, Robert D., primary, Rao, Xi, primary, McCann, Denis, primary, Dropsey, Andrew J., primary, Manro, Jason, primary, Walgren, Jennie, primary, Yuen, Eunice, primary, Rodriguez, Michael J., primary, Plowman, Gregory D., primary, Tiu, Ramon V., primary, Joseph, Sajan, primary, and Peng, Sheng-Bin, primary

Published
2023
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8. Supplementary Figure S4 from ERK Inhibitor LY3214996 Targets ERK Pathway–Driven Cancers: A Therapeutic Approach Toward Precision Medicine

Author

Bhagwat, Shripad V., primary, McMillen, William T., primary, Cai, Shufen, primary, Zhao, Baohui, primary, Whitesell, Matthew, primary, Shen, Weihua, primary, Kindler, Lisa, primary, Flack, Robert S., primary, Wu, Wenjuan, primary, Anderson, Bryan, primary, Zhai, Yan, primary, Yuan, Xiu-Juan, primary, Pogue, Meghann, primary, Van Horn, Robert D., primary, Rao, Xi, primary, McCann, Denis, primary, Dropsey, Andrew J., primary, Manro, Jason, primary, Walgren, Jennie, primary, Yuen, Eunice, primary, Rodriguez, Michael J., primary, Plowman, Gregory D., primary, Tiu, Ramon V., primary, Joseph, Sajan, primary, and Peng, Sheng-Bin, primary

Published
2023
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9. Supplementary Table S3 from ERK Inhibitor LY3214996 Targets ERK Pathway–Driven Cancers: A Therapeutic Approach Toward Precision Medicine

Author

Bhagwat, Shripad V., primary, McMillen, William T., primary, Cai, Shufen, primary, Zhao, Baohui, primary, Whitesell, Matthew, primary, Shen, Weihua, primary, Kindler, Lisa, primary, Flack, Robert S., primary, Wu, Wenjuan, primary, Anderson, Bryan, primary, Zhai, Yan, primary, Yuan, Xiu-Juan, primary, Pogue, Meghann, primary, Van Horn, Robert D., primary, Rao, Xi, primary, McCann, Denis, primary, Dropsey, Andrew J., primary, Manro, Jason, primary, Walgren, Jennie, primary, Yuen, Eunice, primary, Rodriguez, Michael J., primary, Plowman, Gregory D., primary, Tiu, Ramon V., primary, Joseph, Sajan, primary, and Peng, Sheng-Bin, primary

Published
2023
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10. Supplementary tables and figures from Abemaciclib Is Active in Preclinical Models of Ewing Sarcoma via Multipronged Regulation of Cell Cycle, DNA Methylation, and Interferon Pathway Signaling

Author

Dowless, Michele, primary, Lowery, Caitlin D., primary, Shackleford, Terry, primary, Renschler, Matthew, primary, Stephens, Jennifer, primary, Flack, Robert, primary, Blosser, Wayne, primary, Gupta, Simone, primary, Stewart, Julie, primary, Webster, Yue, primary, Dempsey, Jack, primary, VanWye, Alle B., primary, Ebert, Philip, primary, Iversen, Philip, primary, Olsen, Jonathan B., primary, Gong, Xueqian, primary, Buchanan, Sean, primary, Houghton, Peter, primary, and Stancato, Louis, primary

Published
2023
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11. Cold atoms in space: community workshop summary and proposed road-map

Author

Alonso, Iván, primary, Alpigiani, Cristiano, additional, Altschul, Brett, additional, Araújo, Henrique, additional, Arduini, Gianluigi, additional, Arlt, Jan, additional, Badurina, Leonardo, additional, Balaž, Antun, additional, Bandarupally, Satvika, additional, Barish, Barry C., additional, Barone, Michele, additional, Barsanti, Michele, additional, Bass, Steven, additional, Bassi, Angelo, additional, Battelier, Baptiste, additional, Baynham, Charles F. A., additional, Beaufils, Quentin, additional, Belić, Aleksandar, additional, Bergé, Joel, additional, Bernabeu, Jose, additional, Bertoldi, Andrea, additional, Bingham, Robert, additional, Bize, Sébastien, additional, Blas, Diego, additional, Bongs, Kai, additional, Bouyer, Philippe, additional, Braitenberg, Carla, additional, Brand, Christian, additional, Braxmaier, Claus, additional, Bresson, Alexandre, additional, Buchmueller, Oliver, additional, Budker, Dmitry, additional, Bugalho, Luís, additional, Burdin, Sergey, additional, Cacciapuoti, Luigi, additional, Callegari, Simone, additional, Calmet, Xavier, additional, Calonico, Davide, additional, Canuel, Benjamin, additional, Caramete, Laurentiu-Ioan, additional, Carraz, Olivier, additional, Cassettari, Donatella, additional, Chakraborty, Pratik, additional, Chattopadhyay, Swapan, additional, Chauhan, Upasna, additional, Chen, Xuzong, additional, Chen, Yu-Ao, additional, Chiofalo, Maria Luisa, additional, Coleman, Jonathon, additional, Corgier, Robin, additional, Cotter, J. P., additional, Michael Cruise, A., additional, Cui, Yanou, additional, Davies, Gavin, additional, De Roeck, Albert, additional, Demarteau, Marcel, additional, Derevianko, Andrei, additional, Di Clemente, Marco, additional, Djordjevic, Goran S., additional, Donadi, Sandro, additional, Doré, Olivier, additional, Dornan, Peter, additional, Doser, Michael, additional, Drougakis, Giannis, additional, Dunningham, Jacob, additional, Easo, Sajan, additional, Eby, Joshua, additional, Elertas, Gedminas, additional, Ellis, John, additional, Evans, David, additional, Examilioti, Pandora, additional, Fadeev, Pavel, additional, Fanì, Mattia, additional, Fassi, Farida, additional, Fattori, Marco, additional, Fedderke, Michael A., additional, Felea, Daniel, additional, Feng, Chen-Hao, additional, Ferreras, Jorge, additional, Flack, Robert, additional, Flambaum, Victor V., additional, Forsberg, René, additional, Fromhold, Mark, additional, Gaaloul, Naceur, additional, Garraway, Barry M., additional, Georgousi, Maria, additional, Geraci, Andrew, additional, Gibble, Kurt, additional, Gibson, Valerie, additional, Gill, Patrick, additional, Giudice, Gian F., additional, Goldwin, Jon, additional, Gould, Oliver, additional, Grachov, Oleg, additional, Graham, Peter W., additional, Grasso, Dario, additional, Griffin, Paul F., additional, Guerlin, Christine, additional, Gündoğan, Mustafa, additional, Gupta, Ratnesh K., additional, Haehnelt, Martin, additional, Hanımeli, Ekim T., additional, Hawkins, Leonie, additional, Hees, Aurélien, additional, Henderson, Victoria A., additional, Herr, Waldemar, additional, Herrmann, Sven, additional, Hird, Thomas, additional, Hobson, Richard, additional, Hock, Vincent, additional, Hogan, Jason M., additional, Holst, Bodil, additional, Holynski, Michael, additional, Israelsson, Ulf, additional, Jeglič, Peter, additional, Jetzer, Philippe, additional, Juzeliūnas, Gediminas, additional, Kaltenbaek, Rainer, additional, Kamenik, Jernej F., additional, Kehagias, Alex, additional, Kirova, Teodora, additional, Kiss-Toth, Marton, additional, Koke, Sebastian, additional, Kolkowitz, Shimon, additional, Kornakov, Georgy, additional, Kovachy, Tim, additional, Krutzik, Markus, additional, Kumar, Mukesh, additional, Kumar, Pradeep, additional, Lämmerzahl, Claus, additional, Landsberg, Greg, additional, Le Poncin-Lafitte, Christophe, additional, Leibrandt, David R., additional, Lévèque, Thomas, additional, Lewicki, Marek, additional, Li, Rui, additional, Lipniacka, Anna, additional, Lisdat, Christian, additional, Liu, Mia, additional, Lopez-Gonzalez, J. L., additional, Loriani, Sina, additional, Louko, Jorma, additional, Luciano, Giuseppe Gaetano, additional, Lundblad, Nathan, additional, Maddox, Steve, additional, Mahmoud, M. A., additional, Maleknejad, Azadeh, additional, March-Russell, John, additional, Massonnet, Didier, additional, McCabe, Christopher, additional, Meister, Matthias, additional, Mežnaršič, Tadej, additional, Micalizio, Salvatore, additional, Migliaccio, Federica, additional, Millington, Peter, additional, Milosevic, Milan, additional, Mitchell, Jeremiah, additional, Morley, Gavin W., additional, Müller, Jürgen, additional, Murphy, Eamonn, additional, Müstecaplıoğlu, Özgür E., additional, O’Shea, Val, additional, Oi, Daniel K. L., additional, Olson, Judith, additional, Pal, Debapriya, additional, Papazoglou, Dimitris G., additional, Pasatembou, Elizabeth, additional, Paternostro, Mauro, additional, Pawlowski, Krzysztof, additional, Pelucchi, Emanuele, additional, Pereira dos Santos, Franck, additional, Peters, Achim, additional, Pikovski, Igor, additional, Pilaftsis, Apostolos, additional, Pinto, Alexandra, additional, Prevedelli, Marco, additional, Puthiya-Veettil, Vishnupriya, additional, Quenby, John, additional, Rafelski, Johann, additional, Rasel, Ernst M., additional, Ravensbergen, Cornelis, additional, Reguzzoni, Mirko, additional, Richaud, Andrea, additional, Riou, Isabelle, additional, Rothacher, Markus, additional, Roura, Albert, additional, Ruschhaupt, Andreas, additional, Sabulsky, Dylan O., additional, Safronova, Marianna, additional, Saltas, Ippocratis D., additional, Salvi, Leonardo, additional, Sameed, Muhammed, additional, Saurabh, Pandey, additional, Schäffer, Stefan, additional, Schiller, Stephan, additional, Schilling, Manuel, additional, Schkolnik, Vladimir, additional, Schlippert, Dennis, additional, Schmidt, Piet O., additional, Schnatz, Harald, additional, Schneider, Jean, additional, Schneider, Ulrich, additional, Schreck, Florian, additional, Schubert, Christian, additional, Shayeghi, Armin, additional, Sherrill, Nathaniel, additional, Shipsey, Ian, additional, Signorini, Carla, additional, Singh, Rajeev, additional, Singh, Yeshpal, additional, Skordis, Constantinos, additional, Smerzi, Augusto, additional, Sopuerta, Carlos F., additional, Sorrentino, Fiodor, additional, Sphicas, Paraskevas, additional, Stadnik, Yevgeny V., additional, Stefanescu, Petruta, additional, Tarallo, Marco G., additional, Tentindo, Silvia, additional, Tino, Guglielmo M., additional, Tinsley, Jonathan N., additional, Tornatore, Vincenza, additional, Treutlein, Philipp, additional, Trombettoni, Andrea, additional, Tsai, Yu-Dai, additional, Tuckey, Philip, additional, Uchida, Melissa A., additional, Valenzuela, Tristan, additional, Van Den Bossche, Mathias, additional, Vaskonen, Ville, additional, Verma, Gunjan, additional, Vetrano, Flavio, additional, Vogt, Christian, additional, von Klitzing, Wolf, additional, Waller, Pierre, additional, Walser, Reinhold, additional, Wille, Eric, additional, Williams, Jason, additional, Windpassinger, Patrick, additional, Wittrock, Ulrich, additional, Wolf, Peter, additional, Woltmann, Marian, additional, Wörner, Lisa, additional, Xuereb, André, additional, Yahia, Mohamed, additional, Yazgan, Efe, additional, Yu, Nan, additional, Zahzam, Nassim, additional, Zambrini Cruzeiro, Emmanuel, additional, Zhan, Mingsheng, additional, Zou, Xinhao, additional, Zupan, Jure, additional, and Zupanič, Erik, additional

Published
2022
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12. Evolution of Architectural Floor Plans

Author

Flack, Robert W. J., Ross, Brian J., Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, Di Chio, Cecilia, editor, Brabazon, Anthony, editor, Di Caro, Gianni A., editor, Drechsler, Rolf, editor, Farooq, Muddassar, editor, Grahl, Jörn, editor, Greenfield, Gary, editor, Prins, Christian, editor, Romero, Juan, editor, Squillero, Giovanni, editor, Tarantino, Ernesto, editor, Tettamanzi, Andrea G. B., editor, Urquhart, Neil, editor, and Uyar, A. Şima, editor

Published
2011
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13. Cold atoms in space: community workshop summary and proposed road-map

Author

Müstecaplıoğlu, Özgür Esat (ORCID 0000-0002-9134-3951 & YÖK ID 1674), Alonso, Ivan; Alpigiani, Cristiano; Altschul, Brett; Araujo, Henrique; Arduini, Gianluigi; Arlt, Jan; Badurina, Leonardo; Balaz, Antun; Bandarupally, Satvika; Barish, Barry C.; Barone, Michele; Barsanti, Michele; Bass, Steven; Bassi, Angelo; Battelier, Baptiste; Baynham, Charles F. A.; Beaufils, Quentin; Berge, Joel; Bernabeu, Jose; Bertoldi, Andrea; Bingham, Robert; Bize, Sebastien; Blas, Diego; Bongs, Kai; Bouyer, Philippe; Braitenberg, Carla; Brand, Christian; Braxmaier, Claus; Bresson, Alexandre; Buchmueller, Oliver; Budker, Dmitry; Bugalho, Luis; Burdin, Sergey; Cacciapuoti, Luigi; Callegari, Simone; Calmet, Xavier; Calonico, Davide; Canuel, Benjamin; Caramete, Laurentiu-Ioan; Carraz, Olivier; Cassettari, Donatella; Chakraborty, Pratik; Chattopadhyay, Swapan; Chauhan, Upasna; Chen, Xuzong; Chen, Yu-Ao; Chiofalo, Maria Luisa; Coleman, Jonathon; Corgier, Robin; Cotter, J. P.; Cruise, A. Michael; Cui, Yanou; Davies, Gavin; De Roeck, Albert; Demarteau, Marcel; Derevianko, Andrei; Di Clemente, Marco; Djordjevic, Goran S.; Donadi, Sandro; Dore, Olivier; Dornan, Peter; Doser, Michael; Drougakis, Giannis; Dunningham, Jacob; Easo, Sajan; Eby, Joshua; Elertas, Gedminas; Ellis, John; Evans, David; Examilioti, Pandora; Fadeev, Pavel; Fani, Mattia; Fassi, Farida; Fattori, Marco; Fedderke, Michael A.; Felea, Daniel; Feng, Chen-Hao; Ferreras, Jorge; Flack, Robert; Flambaum, Victor V.; Forsberg, Rene; Fromhold, Mark; Gaaloul, Naceur; Garraway, Barry M.; Georgousi, Maria; Geraci, Andrew; Gibble, Kurt; Gibson, Valerie; Gill, Patrick; Giudice, GianF; Goldwin, Jon; Gould, Oliver; Grachov, Oleg; Graham, Peter W.; Grasso, Dario; Griffin, PaulF; Guerlin, Christine; Gupta, Ratnesh K.; Haehnelt, Martin; Hawkins, Leonie; Hees, Aurelien; Henderson, Victoria A.; Herr, Waldemar; Herrmann, Sven; Hird, Thomas; Hobson, Richard; Hock, Vincent; Hogan, Jason M.; Holst, Bodil; Holynski, Michael; Israelsson, Ulf; Jeglic, Peter; Jetzer, Philippe; Juzeliunas, Gediminas; Kaltenbaek, Rainer; Kamenik, College of Sciences, Department of Physics, Müstecaplıoğlu, Özgür Esat (ORCID 0000-0002-9134-3951 & YÖK ID 1674), Alonso, Ivan; Alpigiani, Cristiano; Altschul, Brett; Araujo, Henrique; Arduini, Gianluigi; Arlt, Jan; Badurina, Leonardo; Balaz, Antun; Bandarupally, Satvika; Barish, Barry C.; Barone, Michele; Barsanti, Michele; Bass, Steven; Bassi, Angelo; Battelier, Baptiste; Baynham, Charles F. A.; Beaufils, Quentin; Berge, Joel; Bernabeu, Jose; Bertoldi, Andrea; Bingham, Robert; Bize, Sebastien; Blas, Diego; Bongs, Kai; Bouyer, Philippe; Braitenberg, Carla; Brand, Christian; Braxmaier, Claus; Bresson, Alexandre; Buchmueller, Oliver; Budker, Dmitry; Bugalho, Luis; Burdin, Sergey; Cacciapuoti, Luigi; Callegari, Simone; Calmet, Xavier; Calonico, Davide; Canuel, Benjamin; Caramete, Laurentiu-Ioan; Carraz, Olivier; Cassettari, Donatella; Chakraborty, Pratik; Chattopadhyay, Swapan; Chauhan, Upasna; Chen, Xuzong; Chen, Yu-Ao; Chiofalo, Maria Luisa; Coleman, Jonathon; Corgier, Robin; Cotter, J. P.; Cruise, A. Michael; Cui, Yanou; Davies, Gavin; De Roeck, Albert; Demarteau, Marcel; Derevianko, Andrei; Di Clemente, Marco; Djordjevic, Goran S.; Donadi, Sandro; Dore, Olivier; Dornan, Peter; Doser, Michael; Drougakis, Giannis; Dunningham, Jacob; Easo, Sajan; Eby, Joshua; Elertas, Gedminas; Ellis, John; Evans, David; Examilioti, Pandora; Fadeev, Pavel; Fani, Mattia; Fassi, Farida; Fattori, Marco; Fedderke, Michael A.; Felea, Daniel; Feng, Chen-Hao; Ferreras, Jorge; Flack, Robert; Flambaum, Victor V.; Forsberg, Rene; Fromhold, Mark; Gaaloul, Naceur; Garraway, Barry M.; Georgousi, Maria; Geraci, Andrew; Gibble, Kurt; Gibson, Valerie; Gill, Patrick; Giudice, GianF; Goldwin, Jon; Gould, Oliver; Grachov, Oleg; Graham, Peter W.; Grasso, Dario; Griffin, PaulF; Guerlin, Christine; Gupta, Ratnesh K.; Haehnelt, Martin; Hawkins, Leonie; Hees, Aurelien; Henderson, Victoria A.; Herr, Waldemar; Herrmann, Sven; Hird, Thomas; Hobson, Richard; Hock, Vincent; Hogan, Jason M.; Holst, Bodil; Holynski, Michael; Israelsson, Ulf; Jeglic, Peter; Jetzer, Philippe; Juzeliunas, Gediminas; Kaltenbaek, Rainer; Kamenik, College of Sciences, and Department of Physics

Abstract

We summarise the discussions at a virtual Community Workshop on Cold Atoms in Space concerning the status of cold atom technologies, the prospective scientific and societal opportunities offered by their deployment in space, and the developments needed before cold atoms could be operated in space. The cold atom technologies discussed include atomic clocks, quantum gravimeters and accelerometers, and atom interferometers. Prospective applications include metrology, geodesy and measurement of terrestrial mass change due to, e.g., climate change, and fundamental science experiments such as tests of the equivalence principle, searches for dark matter, measurements of gravitational waves and tests of quantum mechanics. We review the current status of cold atom technologies and outline the requirements for their space qualification, including the development paths and the corresponding technical milestones, and identifying possible pathfinder missions to pave the way for missions to exploit the full potential of cold atoms in space. Finally, we present a first draft of a possible road-map for achieving these goals, that we propose for discussion by the interested cold atom, Earth Observation, fundamental physics and other prospective scientific user communities, together with the European Space Agency (ESA) and national space and research funding agencies., We thank the CERN Quantum Technology Initiative for their support of the workshop that laid the basis for this paper.

Published
2022

14. Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabine

Author

Gelbert, Lawrence M., Cai, Shufen, Lin, Xi, Sanchez-Martinez, Concepcion, del Prado, Miriam, Lallena, Maria Jose, Torres, Raquel, Ajamie, Rose T., Wishart, Graham N., Flack, Robert Steven, Neubauer, Blake Lee, Young, Jamie, Chan, Edward M., Iversen, Philip, Cronier, Damien, Kreklau, Emiko, and de Dios, Alfonso

Published
2014
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16. AEDGE:Atomic Experiment for Dark Matter and Gravity Exploration in Space

Author

El-Neaj, Yousef Abou, Alpigiani, Cristiano, Amairi-Pyka, Sana, Araujo, Henrique, Balaz, Antun, Belic, Aleksandar, Bentine, Elliot, Bernabeu, Jose, Bingham, Robert, Bolpasi, Vasiliki, Bowden, William, Buchmueller, Oliver, Burrage, Clare, Calmet, Xavier, Canuel, Benjamin, Charmandaris, Vassilis, Chen, Xuzong, Coleman, Jonathon, Cotter, Joseph, Cui, Yanou, Derevianko, Andrei, De Roeck, Albert, Drougkakis, Ioannis, Dutan, Ioana, Elertas, Gedminas, Ellis, John, El Sawy, Mai, Fassi, Farida, Felea, Daniel, Feng, Chen-Hao, Flack, Robert, Foot, Chris, Fuentes, Ivette, Gaaloul, Naceur, Gauguet, Alexandre, Geiger, Remi, Gibson, Valerie, Giudice, Gian, Goldwin, Jon, Grachov, Oleg, Graham, Peter W., Grasso, Dario, Van der Grinten, Maurits, Guendogan, Mustafa, Haehnelt, Martin G., Harte, Tiffany, Hees, Aurelien, Hobson, Richard, Hogan, Jason, Holst, Bodil, Holynski, Michael, Kasevich, Mark, Kavanagh, Bradley J., Von Klitzing, Wolf, Kovachy, Tim, Krikler, Benjamin, Krutzik, Markus, Lewicki, Marek, Lien, Yu-Hung, Liu, Miaoyuan, Luciano, Giuseppe Gaetano, Pandey, Saurabh, Paternostro, Mauro, Penning, Bjoern, Peters, Achim, Prevedelli, Marco, Puthiya-Veettil, Vishnupriya, Quenby, John, Rasel, Ernst, Roura, Albert, Sabulsky, Dylan, Sameed, Muhammed, Sauer, Ben, Schaffer, Stefan Alaric, Schiller, Stephan, Schkolnik, Vladimir, Schlippert, Dennis, Schubert, Christian, Sfar, Haifa Rejeb, Shayeghi, Armin, Soares-Santos, Marcelle, Vasilakis, Georgios, Vaskonen, Ville, Vogt, Christian, Webber-Date, Alex, Windpassinger, Patrick, Woltmann, Marian, Yazgan, Efe, Zupan, Jure, El-Neaj, Yousef Abou, Alpigiani, Cristiano, Amairi-Pyka, Sana, Araujo, Henrique, Balaz, Antun, Belic, Aleksandar, Bentine, Elliot, Bernabeu, Jose, Bingham, Robert, Bolpasi, Vasiliki, Bowden, William, Buchmueller, Oliver, Burrage, Clare, Calmet, Xavier, Canuel, Benjamin, Charmandaris, Vassilis, Chen, Xuzong, Coleman, Jonathon, Cotter, Joseph, Cui, Yanou, Derevianko, Andrei, De Roeck, Albert, Drougkakis, Ioannis, Dutan, Ioana, Elertas, Gedminas, Ellis, John, El Sawy, Mai, Fassi, Farida, Felea, Daniel, Feng, Chen-Hao, Flack, Robert, Foot, Chris, Fuentes, Ivette, Gaaloul, Naceur, Gauguet, Alexandre, Geiger, Remi, Gibson, Valerie, Giudice, Gian, Goldwin, Jon, Grachov, Oleg, Graham, Peter W., Grasso, Dario, Van der Grinten, Maurits, Guendogan, Mustafa, Haehnelt, Martin G., Harte, Tiffany, Hees, Aurelien, Hobson, Richard, Hogan, Jason, Holst, Bodil, Holynski, Michael, Kasevich, Mark, Kavanagh, Bradley J., Von Klitzing, Wolf, Kovachy, Tim, Krikler, Benjamin, Krutzik, Markus, Lewicki, Marek, Lien, Yu-Hung, Liu, Miaoyuan, Luciano, Giuseppe Gaetano, Pandey, Saurabh, Paternostro, Mauro, Penning, Bjoern, Peters, Achim, Prevedelli, Marco, Puthiya-Veettil, Vishnupriya, Quenby, John, Rasel, Ernst, Roura, Albert, Sabulsky, Dylan, Sameed, Muhammed, Sauer, Ben, Schaffer, Stefan Alaric, Schiller, Stephan, Schkolnik, Vladimir, Schlippert, Dennis, Schubert, Christian, Sfar, Haifa Rejeb, Shayeghi, Armin, Soares-Santos, Marcelle, Vasilakis, Georgios, Vaskonen, Ville, Vogt, Christian, Webber-Date, Alex, Windpassinger, Patrick, Woltmann, Marian, Yazgan, Efe, and Zupan, Jure

Abstract

We propose in this White Paper a concept for a space experiment using cold atoms to search for ultra-light dark matter, and to detect gravitational waves in the frequency range between the most sensitive ranges of LISA and the terrestrial LIGO/Virgo/KAGRA/INDIGO experiments. This interdisciplinary experiment, called Atomic Experiment for Dark Matter and Gravity Exploration (AEDGE), will also complement other planned searches for dark matter, and exploit synergies with other gravitational wave detectors. We give examples of the extended range of sensitivity to ultra-light dark matter offered by AEDGE, and how its gravitational-wave measurements could explore the assembly of super-massive black holes, first-order phase transitions in the early universe and cosmic strings. AEDGE will be based upon technologies now being developed for terrestrial experiments using cold atoms, and will benefit from the space experience obtained with, e.g., LISA and cold atom experiments in microgravity. KCL-PH-TH/2019-65, CERN-TH-2019-126

Published
2020

18. ERK Inhibitor LY3214996 Targets ERK Pathway–Driven Cancers: A Therapeutic Approach Toward Precision Medicine

Author

Bhagwat, Shripad V., primary, McMillen, William T., additional, Cai, Shufen, additional, Zhao, Baohui, additional, Whitesell, Matthew, additional, Shen, Weihua, additional, Kindler, Lisa, additional, Flack, Robert S., additional, Wu, Wenjuan, additional, Anderson, Bryan, additional, Zhai, Yan, additional, Yuan, Xiu-Juan, additional, Pogue, Meghann, additional, Van Horn, Robert D., additional, Rao, Xi, additional, McCann, Denis, additional, Dropsey, Andrew J., additional, Manro, Jason, additional, Walgren, Jennie, additional, Yuen, Eunice, additional, Rodriguez, Michael J., additional, Plowman, Gregory D., additional, Tiu, Ramon V., additional, Joseph, Sajan, additional, and Peng, Sheng-Bin, additional

Published
2020
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20. Abemaciclib Is Active in Preclinical Models of Ewing Sarcoma via Multipronged Regulation of Cell Cycle, DNA Methylation, and Interferon Pathway Signaling

Author

Dowless, Michele, primary, Lowery, Caitlin D., additional, Shackleford, Terry, additional, Renschler, Matthew, additional, Stephens, Jennifer, additional, Flack, Robert, additional, Blosser, Wayne, additional, Gupta, Simone, additional, Stewart, Julie, additional, Webster, Yue, additional, Dempsey, Jack, additional, VanWye, Alle B., additional, Ebert, Philip, additional, Iversen, Philip, additional, Olsen, Jonathan B., additional, Gong, Xueqian, additional, Buchanan, Sean, additional, Houghton, Peter, additional, and Stancato, Louis, additional

Published
2018
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21. Abstract B43: The CDK4 and 6 inhibitor abemaciclib induces both epigenetic and immunogenic responses in preclinical models of Ewing’s sarcoma

Author

Dowless, Michele, primary, Lowery, Caitlin, additional, Renschler, Matthew, additional, Blosser, Wayne, additional, Stephens, Jennifer, additional, Flack, Robert, additional, Credille, Kelly, additional, Chen, Mia, additional, Dorsey, Frank, additional, Sams, Lillian, additional, Ebert, Philip, additional, Olsen, Jonathan, additional, Shackleford, Terry, additional, Houghton, Peter, additional, and Stancato, Louis, additional

Published
2018
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25. Abstract 583: The CDK4/6 inhibitor abemaciclib induces synergistic immune activation and antitumor efficacy in combination with PD-L1 blockade

Author

Dempsey, Jack, primary, Huber, Lysiane, additional, Forest, Amelie, additional, Stephens, Jennifer R., additional, Doman, Thompson N., additional, Manro, Jason, additional, Capen, Andrew, additional, Flack, Robert S., additional, Donoho, Gregory P., additional, Buchanan, Sean, additional, Dios, Alfonso De, additional, Driscoll, Kyla, additional, Kalos, Michael, additional, Novosiadly, Ruslan, additional, Beckmann, Richard P., additional, and Schaer, David A., additional

Published
2017
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26. Abstract 3231: Identifying high quality, potent and selective pyrimidinylthienopyrrolone inhibitors of ERK1/2 kinase: LY3214996

Author

Zhao, Gaiying, primary, McMillen, William T., additional, Cai, Shufen, additional, Zhao, Baohui, additional, Whitesell, Matthew, additional, Wu, Wenjuan, additional, Huss, Karen, additional, Anderson, Bryan, additional, Yuan, Xiu-Juan, additional, Jaken, Susan, additional, Kindler, Lisa, additional, Flack, Robert S., additional, McCann, Denis, additional, Mathes, Brian, additional, Dropsey, Andrew J., additional, Walgren, Jennie, additional, Yuen, Eunice, additional, Manro, Jason, additional, Gong, Xueqian, additional, Cortez, Guillermo, additional, McLean, Johnathan, additional, Rodriguez, Michael J., additional, Tiu, Ramon V., additional, Bhagwat, Shripad V., additional, and Joseph, Sajan, additional

Published
2017
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27. Abstract 317: Combination of a novel ERK1/2 inhibitor (LY3214996) with CDK4 and CDK6 inhibitor (abemaciclib) enhances antitumor efficacy in KRAS mutant non-small cell lung cancer (NSCLC)

Author

Wu, Wenjuan, primary, Bhagwat, Shripad V., additional, King, Constance, additional, Pratt, Susan, additional, Gong, Xueqian, additional, Stewart, Julie, additional, Jones, Bonita, additional, Flack, Robert, additional, Beckman, Richard, additional, Falcon, Beverly, additional, Manro, Jason, additional, McMillen, William T., additional, Tiu, Ramon V., additional, Peng, Sheng-Bin, additional, Reinhard, Christoph, additional, Joseph, Sajan, additional, and Buchanan, Sean, additional

Published
2017
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28. Abstract 4973: Discovery of LY3214996, a selective and novel ERK1/2 inhibitor with potent antitumor activities in cancer models with MAPK pathway alterations

Author

Bhagwat, Shripad V., primary, McMillen, William T., additional, Cai, Shufen, additional, Zhao, Baohui, additional, Whitesell, Matthew, additional, Kindler, Lisa, additional, Flack, Robert S., additional, Wu, Wenjuan, additional, Huss, Karen, additional, Anderson, Bryan, additional, Yuan, Xiu-Juan, additional, Jaken, Susan, additional, McCann, Denis, additional, Mathes, Brian, additional, Dropsey, Andrew J., additional, Manro, Jason, additional, Walgren, Jennie, additional, Yuen, Eunice, additional, Gong, Xueqian, additional, Rodriguez, Michael J., additional, Huang, Jianping, additional, Tiu, Ramon V., additional, Joseph, Sajan, additional, and Peng, Sheng-Bin, additional

Published
2017
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29. Abstract 930: Combined inhibition of pan-RAF and VEGFR-2 mediates antitumor activity in KRAS mutant non-small cell lung cancer (NSCLC) through enhanced inhibition of tumor angiogenesis and growth

Author

Wu, Wenjuan, primary, Stewart, Julie, additional, King, Constance, additional, Jones, Bonita, additional, Flack, Robert, additional, Pratt, Susan, additional, Berryman, Randi, additional, Swearingen, Michelle, additional, Bodenmiller, Diane, additional, Lin, Xi, additional, Uhlik, Mark, additional, Falcon, Beverly, additional, Fischl, Anthony, additional, Manro, Jason, additional, Tiu, Ramon, additional, Chintharlapalli, Sudhakar, additional, Pytowski, Bronislaw, additional, Bhagwat, Shripad V., additional, Buchanan, Sean, additional, and Peng, Sheng-Bin, additional

Published
2016
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30. Window Shopping

Author

Warr, Andrew, primary, Chi, Ed H., additional, Harris, Helen, additional, Kuscher, Alexander, additional, Chen, Jenn, additional, Flack, Robert, additional, and Jitkoff, Nicholas, additional

Published
2016
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31. Measurement of the double-beta decay half-life on Nd-150 and search for neutrinoless decay modes with the NEMO-3 detector

Author

Argyriades, J., Arnold, R., Augier, C., Baker, J., Barabash, A. S., Basharina-Freshville, A., Bongrand, M., Broudin, G., Caffrey, A. J., Chauveau, E., Daraktchieva, Z., Durand, D., Egorov, V. G., Fatemi-Ghomi, N., Flack, Robert L., Hubert, P., Jerie, J., Jullian, S., Kauer, M., King, S., Klimenko, A., Kochetov, O. I., Konovalov, S. I., Kovalenko, V. E., Lalanne, D., Lamhamdi, T., Lang, K., Lemiere, Y., Longuemare, C., Lutter, G., Marquet, C., Martín-Albo, Justo, Mauger, F., Nachab, A., Nasteva, I., Nemchenok, I. B., Nova, F., Novella, Pau, Oshumi, H., Pahlka, R. B., Perrot, F., Piquemal, F., Reyss, J. L., Ricol, J. S., Saakyan, R., Sarazin, X., Simard, L., Simkovic, F., Shitov, Y. A., Smolnikov, A., Snow, S., Soldner-Rembold, S., Stekl, I., Suhonen, J., Sutton, C. S., Szklarz, G., Thomas, J., Timkin, V. V., Tretyak, V. I., Umatov, V., Vala, L., Vanyushin, I. A., Vasiliev, V. A., Vorobel, V., Vylov, T., and NEMO Collaboration

Abstract

The half-life for double-beta decay of Nd-150 has been measured by the NEMO-3 experiment at the Modane Underground Laboratory. Using 924.7 days of data recorded with 36.55 g of Nd-150, we measured the half-life for 2 nu beta beta decay to be T-1/2(2 nu) = (9.11(-0.22)(+0.25)(stat.) +/- 0.63(syst.)) x 10(18) yr. The observed limit on the half-life for neutrinoless double-beta decay is found to be T-1/2(0 nu) > 1.8 x 10(22) yr at 90% confidence level. This translates into a limit on the effective Majorana neutrino mass of < m(nu)> < 4.0-6.3 eV if the nuclear deformation is taken into account. We also set limits on models involving Majoron emission, right-handed currents, and transitions to excited states., We thank the staff at the Modane Underground Laboratory for its technical assistance in running the experiment,Vladimir Tretyak for providing the Monte Carlo event generator, and Wade Fisher for helping with the limit-setting program. We acknowledge support by the grants agencies of the Czech Republic, RFBR (Russia), STFC (UK), and NSF (USA).

Published
2009

33. Measurement of the background in the NEMO 3 double beta decay experiment

Author

Argyriades, J., Arnold, R., Augier, C., Baker, J., Barabash, A. S., Bongrand, M., Borudin-Bay, G., Brudanin, V. B., Caffrey, A. J., Chapon, A., Chauveau, E., Daraktchieva, Z., Durand, D., Egorov, V. G., Fatemi-Ghomi, N., Flack, Robert L., Freshville, A., Guillon, B., Hubert, P., Julian, S., Kauer, M., King, S., Kochetov, O. I., Konovalov, S. I., Kovalenko, V. E., Lalanne, D., Lang, K., Lemiere, Y., Lutter, G., Mamedov, F., Marquet, C., Martín-Albo, Justo, Mauger, F., Nachab, A., Nasteva, I., Nemchenok, I. B., Nguyen, C. H., Nova, F., Novella, Pau, Ohsumi, H., Pahlka, R. B., Perrot, F., Piquemal, F., Reyss, J. L., Ricol, J. S., Saakyan, R., Sarazin, X., Simard, L., Shitov, Y. A., Smolnikov, A., Snow, S., Soldner-Rembold, S., Stekl, I., Sutton, C. S., Szklarz, G., Thomas, J., Timkin, V. V., Tretyak, V. I., Vala, L., Vanyushin, I. A., Vasiliev, V. A., Vorobel, V., Vylov, T., NEMO Collaboration, Argyriades, J., Arnold, R., Augier, C., Baker, J., Barabash, A. S., Bongrand, M., Borudin-Bay, G., Brudanin, V. B., Caffrey, A. J., Chapon, A., Chauveau, E., Daraktchieva, Z., Durand, D., Egorov, V. G., Fatemi-Ghomi, N., Flack, Robert L., Freshville, A., Guillon, B., Hubert, P., Julian, S., Kauer, M., King, S., Kochetov, O. I., Konovalov, S. I., Kovalenko, V. E., Lalanne, D., Lang, K., Lemiere, Y., Lutter, G., Mamedov, F., Marquet, C., Martín-Albo, Justo, Mauger, F., Nachab, A., Nasteva, I., Nemchenok, I. B., Nguyen, C. H., Nova, F., Novella, Pau, Ohsumi, H., Pahlka, R. B., Perrot, F., Piquemal, F., Reyss, J. L., Ricol, J. S., Saakyan, R., Sarazin, X., Simard, L., Shitov, Y. A., Smolnikov, A., Snow, S., Soldner-Rembold, S., Stekl, I., Sutton, C. S., Szklarz, G., Thomas, J., Timkin, V. V., Tretyak, V. I., Vala, L., Vanyushin, I. A., Vasiliev, V. A., Vorobel, V., Vylov, T., and NEMO Collaboration

Abstract

In the double beta decay experiment NEMO 3 a precise knowledge of the background in the signal region is of outstanding importance. This article presents the methods used in NEMO 3 to evaluate the backgrounds resulting from most if not all possible origins. It also illustrates the power of the combined tracking-calorimetry technique used in the experiment.

Published
2009

34. Abstract B233: Identification and characterization of LY2835219: A potent oral inhibitor of the cyclin-dependent kinases 4 and 6 (CDK4/6) with broad in vivo antitumor activity.

Author

Gelbert, Lawrence M., primary, Cai, Shufen, additional, Lin, Xi, additional, Sanchez-Martinez, Concepcion, additional, del Prado, Miriam, additional, Lallena, Maria Jose, additional, Torres, Raquel, additional, Ajamie, Rose T., additional, Kreklau, Emiko, additional, Wishart, Graham N., additional, Flack, Robert Steven, additional, Neubauer, Blake, additional, Young, Jamie, additional, Chan, Edward M., additional, Iversen, Phillip, additional, Cronier, Damien, additional, and De Dios, Alfonso, additional

Published
2011
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37. Robert Flack : This is True to Me

Author

Flack, Robert and Flack, Robert

Abstract

In collaboration with the "Eternal Cosmic Love Machine Collective," Flack's posthumously published bookwork documents the progression of his illness and the premise of this final project, drawn from notes and diaries. The accompanying CD, dedicated to Flack, includes nine tracks by the musician Zeally.

Published
1994

40. A Sturdy Stance.

Author

Flack, Robert

Subjects
WATERING troughs, CALVES, BARRELS, IRONWORK, IRON pipe
Abstract

The author discusses how he built a trough using a 55-gallon barrels, angle iron and 3 inches iron pipe. He states that using the said materials, he built a trough that stays upright and bears the force of feeding time. He cut two barrels in half, using a power saw. After that, he welded an iron frame that cradles the barrels and bolted the barrels to the frame. Extra bracing underneath, on the barrels' side and between the legs helps the feeder stand firm when the calves come running.

Published
2008

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