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Your search keyword '"Fléron, Marie-Hélène"' showing total 24 results
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24 results on '"Fléron, Marie-Hélène"'

6. In Reply

Author

Monsel, Antoine, primary, Le Corre, Marine, additional, Brisson, Hélène, additional, Arbelot, Charlotte, additional, Vezinet, Corinne, additional, Fléron, Marie-Hélène, additional, Lu, Qin, additional, Langeron, Olivier, additional, and Rouby, Jean-Jacques, additional

Published
2016
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7. Tapered-cuff Endotracheal Tube Does Not Prevent Early Postoperative Pneumonia Compared with Spherical-cuff Endotracheal Tube after Major Vascular Surgery

Author

Monsel, Antoine, primary, Lu, Qin, additional, Le Corre, Marine, additional, Brisson, Hélène, additional, Arbelot, Charlotte, additional, Vezinet, Corinne, additional, Fléron, Marie-Hélène, additional, Ibanez-Estève, Christina, additional, Zerimech, Farid, additional, Balduyck, Malika, additional, Dexheimer, Felippe, additional, Wang, Chunyao, additional, Langeron, Olivier, additional, and Rouby, Jean-Jacques, additional

Published
2016
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14. Type IV Thoracoabdominal Aneurysm Repair: Predictors of Postoperative Mortality, Spinal Cord Injury, and Acute Intestinal Ischemia

Author

Kieffer, Edouard, primary, Chiche, Laurent, additional, Godet, Gilles, additional, Koskas, Fabien, additional, Bahnini, Amine, additional, Bertrand, Michèle, additional, Fléron, Marie-Hélène, additional, Goarin, Jean-Pierre, additional, Warnier de Wailly, Geoffroy, additional, and Benhamou, Albert-Claude, additional

Published
2008
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23. Atenolol administration via a nasogastric tube after abdominal surgery: an unreliable route.

Author

Gosgnach M, Aymard G, Huraux C, Fléron MH, Coriat P, and Diquet B

Subjects
Adrenergic beta-Antagonists pharmacokinetics, Area Under Curve, Atenolol pharmacokinetics, Biological Availability, Half-Life, Heart Rate drug effects, Humans, Abdomen surgery, Adrenergic beta-Antagonists administration & dosage, Atenolol administration & dosage, Intubation, Gastrointestinal
Abstract

beta-adrenoceptor antagonists, especially atenolol, reduce perioperative cardiac morbidity. Because there are no data on the bioavailability of atenolol given by nasogastric tube in the postoperative period, we assessed the efficacy of this route of administration in 18 patients scheduled for abdominal surgery. We found a 36% reduction in the area under the atenolol concentration curve and a 46% reduction in the peak concentration of atenolol in the postoperative period compared with preoperative values. In addition, patients had more rapid mean heart rates on the second postoperative day compared with the day before surgery. We conclude that the administration of atenolol via nasogastric tube in the postoperative period does not result in adequate plasma concentrations.

Published
2005
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24. A comparison of intrathecal opioid and intravenous analgesia for the incidence of cardiovascular, respiratory, and renal complications after abdominal aortic surgery.

Author

Fléron MH, Weiskopf RB, Bertrand M, Mouren S, Eyraud D, Godet G, Riou B, Kieffer E, and Coriat P

Subjects
Aged, Analgesics, Opioid administration & dosage, Blood Gas Analysis, Double-Blind Method, Electrocardiography drug effects, Female, Humans, Injections, Intravenous, Injections, Spinal, Male, Middle Aged, Neurons, Afferent drug effects, Pain, Postoperative drug therapy, Pain, Postoperative epidemiology, Postoperative Care, Postoperative Complications etiology, Prospective Studies, Treatment Outcome, Analgesics, Opioid therapeutic use, Aorta, Abdominal surgery, Cardiovascular Diseases epidemiology, Cardiovascular Diseases etiology, Kidney Diseases epidemiology, Kidney Diseases etiology, Postoperative Complications epidemiology, Respiratory Tract Diseases epidemiology, Respiratory Tract Diseases etiology, Vascular Surgical Procedures adverse effects
Abstract

Unlabelled: Major surgery evokes a stress response that can produce deleterious consequences, especially in a population at high risk for those complications. We tested the hypothesis that decreasing or eliminating one of the sources of stress by providing intense analgesia in the immediate postoperative period via application of neuraxial opioids would decrease major nonsurgical complications. Two-hundred-seventeen patients scheduled to undergo abdominal aortic surgery were randomly allocated to receive either general anesthesia alone (control) or general anesthesia combined with intrathecal opioid (1 micro g/kg sufentanil with 8 micro g/kg preservative-free morphine injected at the L4-5 interspace). Postoperative care was identical in the two groups, including patient-controlled analgesia. Each patient provided an assessment of postoperative pain using a visual analog scale. Postopera-tive complications were recorded according to criteria established a priori. The administration of intrathecal opioid provided more intense analgesia than patient-controlled analgesia during the first 24 h postoperatively (P < 0.05). There was no difference between groups for the incidence of combined major cardiovascular, respiratory, and renal complications (P > 0.05) or mortality (P > 0.05). The incidence of myocardial damage or infarction, as defined by abnormal plasma concentration of troponin I, did not differ between the two groups (P > 0.05). In patients undergoing major abdominal vascular surgery, decrease of one contributor to postoperative stress, by provision of intense analgesia for the intraoperative and initial postoperative period, via application of neuraxial opioid, does not alter the combined major cardiovascular, respiratory, and renal complication rate., Implications: Provision of intense analgesia for the initial postoperative period after major abdominal vascular surgery, via the administration of neuraxial opioid, does not alter the combined incidence of major cardiovascular, respiratory, and renal complications.

Published
2003
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