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5. Safety and efficacy of subcutaneous iscalimab (CFZ533) in two distinct populations of patients with Sjögren's disease (TWINSS): week 24 results of a randomised, double-blind, placebo-controlled, phase 2b dose-ranging study

Author

Maid, Pablo, Rillo, Oscar, Inderjeeth, Charles, Scheinecker, Clemens, Hermann, Josef, Marcolino, Flora Maria D'Andrea, Dias, Laiza H, Scafuto, Antonio, Bookman, Arthur AM, Fortin, Isabelle, Morin, Frederic, Goio, Elizabeth Jean Moreno, Pezo Ruiz, Ninette, Roman Zamoran, Carlos Patricio, Gonzalez Abarzua, Ivan Antonio, Elgueta, Sergio Fabian, Forero Illera, Elias Gonzalo, Marquez Herndez, Javier Dario, Garcia, Alex Echeverri, Pensec, Valerie Devauchelle, Hachulla, Eric, Mariette, Xavier, Gottenberg, Jacques-Eric, Le Guern, Veronique, Finzel, Stephanie, Schaefer, Valentin, Tony, Hans-Peter, Thomas Schmalzing, Marc, Tausche-Wunderlich, Anne-Kathrin, Tzioufas, Athanasios, Balog, Attila, Rojkovich, Bernadette, Varga, Tunde, Lidar, Merav, Rosner, Itzhak, Levy, Yair, Dagna, Lorenzo, Mosca, Marta, Quartuccio, Luca, Nishiyama, Susumu, Kodera, Masanari, Kaneko, Yuko, Okada, Masato, Ueki, Yukitaka, Hwan Park, Sung, van Daele, Paulus Leon Arthur, Bootsma, Hendrika, Duarte Barcelos, Filipe Alexandre, Crispim Romao, Vasco Madeira, Raimundo Vinagre, Filipe Manuel, Tavaresda Costa, Jose Antonio, Rednic, Simona, Duca, Liliana, Maslyanskiy, Alexey, Yakupova, Svetlana, Bugrova, Olga, Izmozherova, Nadezhda, Zotkin, Evgenyi, Nikolaevna Anoshenkova, Olga, Kvarnstrom, Marika, Tufan, Abdurrahman, Fisher, Benjamin, Yee, Chee Seng, Parker, Benjamin Joseph, Grader Beck, Thomas, Lawrence Ford, Theresa, Papas, Athena, Carsons, Steven, Thiagarajan, Saravanan, Zero, Domenick, McCoy, Sara, Sandorfi, Nora, Fisher, Benjamin A, Grader-Beck, Thomas, Ng, Wan-Fai, van Daele, P L A, Noaiseh, Ghaith, Elgueta, Sergio, McCoy, Sara S, Akpek, Esen, Bookman, Arthur, Sopala, Monika, Montecchi-Palmer, Michela, Luo, Wen-Lin, Scheurer, Cornelia, and Hueber, Wolfgang

Published
2024
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6. Reliability Exercise of Ultrasound Salivary Glands in Sjögren’s Disease: An International Web Training Initiative

Author

Quéré, Baptiste, Saraux, Alain, Carvajal-Alegria, Guillermo, Guellec, Dewi, Mouterde, Gaël, Lamotte, Christophe, Hammenfors, Daniel, Jonsson, Malin, Choi, Sung-Eun, Hong-Ki, Min, Stel, Alja, Fisher, Benjamin A., Maybury, Mark, Hofauer, Benedikt, Ferro, Francesco, Milic, Vera, Direnzo, Dana, Devauchelle-Pensec, Valérie, and Jousse-Joulin, Sandrine

Published
2024
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7. The Third Administrator? Perceptions of School Resource Officers in Predominantly White Elementary Schools

Author

Viano, Samantha, Curran, F. Chris, Fisher, Benjamin W., and Kupchik, Aaron

Abstract

Purpose: While studies of collective leadership tend to focus on administrators and teachers, schools have other staff present that contribute to leadership in ways that affect the students. We focus on school resource officers (SROs), which have become increasingly common in suburban, predominately White schools and elementary schools because, absent law enforcement responsibilities, little is known about SROs in these settings. We examine perceptions of SRO impacts while exploring differences across roles and between White and non-White participants. Methods: The study is mixed methods, drawing on interviews, focus groups, and surveys of SROs, administrators, teachers, students, and parents. The setting is a suburban county with SROs in all elementary schools. Findings: We describe seven domains of SRO impacts ranging from school climate to learning environments. SROs are often seen as providing general assistance similar to a vice principal, with some describing SROs as an auxiliary "third administrator." In addition, SROs tend to over-estimate their positive effects compared to school-based stakeholders and underestimate their role in student discipline compared to non-White stakeholders. Implications for Research and Practice: Understanding that SROs in elementary schools can be seen as part of schools' collective leadership helps us to understand the influence they have on students and the school environment. We question the appropriateness of SROs inclusion in collective leadership, suggesting school leaders not rely on SROs for non-law enforcement duties, if at all. The results have implications for future collective leadership studies and understanding why efforts to remove police from schools have often stalled.

Published
2023
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8. Advancing the Real-World Evidence for Medical Devices through Coordinated Registry Networks

Author

Sedrakyan, Art, Marinac-Dabic, Danica, Campbell, Bruce, Aryal, Suvekshya, Baird, Courtney E, Goodney, Philip, Cronenwett, Jack L, Beck, Adam W, Paxton, Elizabeth W, Hu, Jim, Brindis, Ralph, Baskin, Kevin, Cowley, Terrie, Levy, Jeffery, Liebeskind, David S, Poulose, Benjamin K, Rardin, Charles R, Resnic, Frederic S, Tcheng, James, Fisher, Benjamin, Viviano, Charles, Devlin, Vincent, Sheldon, Murray, Eldrup-Jorgensen, Jens, Berlin, Jesse A, Drozda, Joseph, Matheny, Michael E, Dhruva, Sanket S, Feeney, Timothy, Mitchell, Kristi, and Pappas, Gregory

Subjects
Information and Computing Sciences, Health Services and Systems, Health Sciences, Generic health relevance, device safety, device surveillance, health care quality, access, and evaluation, health technology, real world evidence
Abstract

ObjectivesGenerating and using real-world evidence (RWE) is a pragmatic solution for evaluating health technologies. RWE is recognized by regulators, health technology assessors, clinicians, and manufacturers as a valid source of information to support their decision-making. Well-designed registries can provide RWE and become more powerful when linked with electronic health records and administrative databases in coordinated registry networks (CRNs). Our objective was to create a framework of maturity of CRNs and registries, so guiding their development and the prioritization of funding.Design setting and participantsWe invited 52 stakeholders from diverse backgrounds including patient advocacy groups, academic, clinical, industry and regulatory experts to participate on a Delphi survey. Of those invited, 42 participated in the survey to provide feedback on the maturity framework for CRNs and registries. An expert panel reviewed the responses to refine the framework until the target consensus of 80% was reached. Two rounds of the Delphi were distributed via Qualtrics online platform from July to August 2020 and from October to November 2020.Main outcome measuresConsensus on the maturity framework for CRNs and registries consisted of seven domains (unique device identification, efficient data collection, data quality, product life cycle approach, governance and sustainability, quality improvement, and patient-reported outcomes), each presented with five levels of maturity.ResultsOf 52 invited experts, 41 (79.9%) responded to round 1; all 41 responded to round 2; and consensus was reached for most domains. The expert panel resolved the disagreements and final consensus estimates ranged from 80.5% to 92.7% for seven domains.ConclusionsWe have developed a robust framework to assess the maturity of any CRN (or registry) to provide reliable RWE. This framework will promote harmonization of approaches to RWE generation across different disciplines and health systems. The domains and their levels may evolve over time as new solutions become available.

Published
2022

11. Tailoring the treatment of inflammatory rheumatic diseases by a better stratification and characterization of the clinical patient heterogeneity. Findings from a systematic literature review and experts' consensus

Author

Ruscitti, Piero, Allanore, Yannick, Baldini, Chiara, Barilaro, Giuseppe, Bartoloni Bocci, Elena, Bearzi, Pietro, Bellis, Elisa, Berardicurti, Onorina, Biaggi, Alice, Bombardieri, Michele, Cantarini, Luca, Cantatore, Francesco Paolo, Caporali, Roberto, Caso, Francesco, Cervera, Ricard, Ciccia, Francesco, Cipriani, Paola, Chatzis, Loukas, Colafrancesco, Serena, Conti, Fabrizio, Corberi, Erika, Costa, Luisa, Currado, Damiano, Cutolo, Maurizio, D'Angelo, Salvatore, Del Galdo, Francesco, Di Cola, Ilenia, Di Donato, Stefano, Distler, Oliver, D'Onofrio, Bernardo, Doria, Andrea, Fautrel, Bruno, Fasano, Serena, Feist, Eugen, Fisher, Benjamin A., Gabini, Marco, Gandolfo, Saviana, Gatto, Mariele, Genovali, Irene, Gerli, Roberto, Grembiale, Rosa Daniela, Guggino, Giuliana, Hoffmann-Vold, Anna Maria, Iagnocco, Annamaria, Iaquinta, Francesco Salvatore, Liakouli, Vasiliki, Manoussakis, Menelaos N., Marino, Annalisa, Mauro, Daniele, Montecucco, Carlomaurizio, Mosca, Marta, Naty, Saverio, Navarini, Luca, Occhialini, Daniele, Orefice, Valeria, Perosa, Federico, Perricone, Carlo, Pilato, Andrea, Pitzalis, Costantino, Pontarini, Elena, Prete, Marcella, Priori, Roberta, Rivellese, Felice, Sarzi-Puttini, Piercarlo, Scarpa, Raffaele, Sebastiani, Giandomenico, Selmi, Carlo, Shoenfeld, Yehuda, Triolo, Giovanni, Trunfio, Francesca, Yan, Qingran, Tzioufas, Athanasios G., and Giacomelli, Roberto

Published
2024
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13. The Sjögren's Working Group: The 2023 OMERACT meeting and provisional domain generation

Author

Gordon, Rachael A., Nguyen, Yann, Foulquier, Nathan, Beydon, Maxime, Gheita, Tamer A, Hajji, Raouf, Sahbudin, Ilfita, Hoi, Alberta, Ng, Wan-Fai, Mendonça, Jose Alexandre, Wallace, Daniel J, Shea, Beverley, Bruyn, George AW, Goodman, Susan M, Fisher, Benjamin A, Baldini, Chiara, Torralba, Karina D, Bootsma, Hendrika, Akpek, Esen K, Karakus, Sezen, Baer, Alan N, Chakravarty, Soumya D, Terslev, Lene, D'Agostino, Maria-Antonietta, Mariette, Xavier, DiRenzo, Dana, Rasmussen, Astrid, Papas, Athena, Montoya, Cristina, Arends, Suzanne, Yusof, Md Yuzaiful Md, Pintilie, Ionut, Warner, Blake M., Hammitt, Katherine M., Strand, Vibeke, Bouillot, Coralie, Tugwell, Peter, Inanc, Nevsun, Andreu, José Luis, Wahren-Herlenius, Marie, Devauchelle-Pensec, Valerie, Shiboski, Caroline H., Benyoussef, Anas, Masli, Sharmila, Lee, Adrian Y.S., Cornec, Divi, Bowman, Simon, Rischmueller, Maureen, McCoy, Sara S, and Seror, Raphaele

Published
2024
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14. Abatacept in individuals at high risk of rheumatoid arthritis (APIPPRA): a randomised, double-blind, multicentre, parallel, placebo-controlled, phase 2b clinical trial

Author

Norton, Sam, Lempp, Heidi, Opena, Maria, Subesinghe, Sujith, Garrood, Toby, Menon, Bina, Ng, Nora, Douglas, Karen, Koutsianas, Christos, Cooles, Faye, Falahee, Marie, Echavez-Naguicnic, Irene, Bharadwaj, Anurag, Villaruel, Michael, Pande, Ira, Collins, David, Pegler, Suzannah, Raizada, Sabrina, Siebert, Stefan, Fragoulis, George, Guinto, Jesusa, Galloway, James, Rutherford, Andrew, Barnes, Theresa, Jeffrey, Helen, Patel, Yusuf, Batley, Michael, O'Reilly, Brendan, Venkatachalam, Srivinisan, Sheeran, Thomas, Gorman, Claire, Reynolds, Piero, Khan, Asad, Gullick, Nicola, Banerjee, Siwalik, Mankia, Kulveer, Jordan, Deepak, Rowlands, Jane, Starmans-Kool, Mirian, Taylor, James, Nandi, Pradip, Sahbudin, Ilfita, Maybury, Mark, Hider, Samantha, Barcroft, Ann, McNally, Jeremy, Kitchen, Jo, Nisar, Muhammad, Quick, Vanessa, Cope, Andrew P, Jasenecova, Marianna, Vasconcelos, Joana C, Filer, Andrew, Raza, Karim, Qureshi, Sumera, D'Agostino, Maria Antonietta, McInnes, Iain B, Isaacs, John D, Pratt, Arthur G, Fisher, Benjamin A, Buckley, Christopher D, Emery, Paul, Ho, Pauline, Buch, Maya H, Ciurtin, Coziana, van Schaardenburg, Dirkjan, Huizinga, Thomas, Toes, René, Georgiou, Evangelos, Kelly, Joanna, Murphy, Caroline, and Prevost, A Toby

Published
2024
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15. Are Achievement Gaps Related to Discipline Gaps? Evidence from National Data

Author

Pearman, Francis A., Curran, F. Chris, Fisher, Benjamin, and Gardella, Joseph

Abstract

There is growing interest in the relation between the racial achievement gap and the racial discipline gap. However, few studies have examined this relation at the national level. This study combines data from the Stanford Education Data Archive and the Civil Rights Data Collection and employs a district fixed effects analysis to examine whether and the extent to which racial discipline gaps are related to racial achievement gaps in Grades 3 through 8 in districts across the United States. In bivariate models, we find evidence that districts with larger racial discipline gaps have larger racial achievement gaps (and vice versa). Though other district-level differences account for the positive association between the Hispanic-White discipline gap and the Hispanic-White achievement gap, we find robust evidence that the positive association between the Black-White discipline gap and the Black-White achievement gap persists after controlling for a multitude of confounding factors. We also find evidence that the mechanisms connecting achievement to disciplinary outcomes are more salient for Black than White students.

Published
2019

16. The Critique of Myth in German-Jewish Thought

Author

Fisher, Benjamin

Subjects
Religion, Critical theory, Disenchantment, German-Jewish thought, Intellectual history, Myth, Religion
Abstract

Taking up the opposition between Judaism and myth commonly invoked in modern Jewish thought, this dissertation traces its origins in nineteenth and twentieth century German-Jewish thinkers such as Heymann Steinthal, Hermann Cohen, Sigmund Freud, Erich Auerbach, Ernst Cassirer, and Theodor Adorno. It demonstrates how the imagined antagonism between Judaism and myth was formulated in response to supersessionist, anti-Jewish trends in the European study of comparative mythology, the colonial construction of religion, German nationalism, and emerging racial antisemitism. Further, it argues that, haunted by the very romanticism it repudiated, the German-Jewish critique of myth paradoxically entailed the construction of a new one: the myth of the Jews as the sole inventors of rationality, ethics, science, enlightenment, and disenchantment in world history. However, rather than warranting a rejection of disenchantment, the project contends that the critique of myth nonetheless challenges contemporary valorizations of re-enchantment in the scholarly and public spheres.

Published
2024

22. Are Children of Welfare Recipients at a Heightened Risk of Bullying and Peer Victimization?

Author

Hong, Jun Sung, Choi, Jungtae, Espelage, Dorothy L., Wu, Chi-Fang, Boraggina-Ballard, Lena, and Fisher, Benjamin W.

Abstract

Background: Children who come from families on welfare or government assistance might be at risk for bullying involvement. As research has shown, children living in poverty and experiencing family economic hardship are significantly likely to be involved in bullying in school. Objective: This study investigates whether welfare assistance is associated with children's bullying victimization and perpetration, controlling for the covariates including mother (educational level, marital status, employment status, perceived parenting) and child (sex, age, race/ethnicity) characteristics. The study also explores whether various kinds of welfare assistance programs, such as Medicaid, Cash Assistance, SNAP, free/reduced breakfasts or lunches at school and the WIC program are independently associated with children's bullying victimization and perpetration, controlling for the covariates. Method: Participants were 15,010 caregivers of children, ages 6-11 years, who completed the National Survey of Children's Health (NSCH). Results: Results suggest that children receiving welfare assistance were more likely to be victims and perpetrators of bullying than children not on assistance. All of the welfare assistance variables were associated with increased odds of bullying perpetration, and three out of five welfare assistance programs--Medicaid, SNAP, and free/reduced breakfasts or lunches at school were statistically significantly associated with increased odds of bullying victimization. Conclusion: Children in families receiving welfare assistance appear to be at an increased risk of being both victims and perpetrators of bullying, which suggests a need for bullying programming for this population.

Published
2021
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23. Kindergarten Cop: A Case Study of How a Coalition between School Districts and Law Enforcement Led to School Resource Officers in Elementary Schools

Author

Viano, Samantha, Curran, F. Chris, and Fisher, Benjamin W.

Abstract

Adopting school resource officers (SROs) is a popular response to school shootings. Using the advocacy coalition and multiple streams frameworks, we explore how school districts in one county formed a coalition with the Sheriff's Department, adopting SROs in elementary schools following the Sandy Hook shooting. We describe how this coalition was bound together by shared beliefs on school safety and the goodness of law enforcement. The implementation activities of SROs related to the beliefs of the coalition, focusing on security and relationship building. The beliefs were not uniformly understood by SROs--many interpreted their role to include student discipline and managing behavior of students with disabilities. The findings show the utility of comparing policy adoption processes with implementation activities.

Published
2021
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24. Do Interactions with School Resource Officers Predict Students' Likelihood of Being Disciplined and Feelings of Safety? Mixed-Methods Evidence from Two School Districts

Author

Curran, F. Chris, Viano, Samantha, Kupchik, Aaron, and Fisher, Benjamin W.

Abstract

School resource officers (SROs) are common in schools, yet consequences of their presence are poorly understood. This study leveraged mixed-methods data from student surveys and group interviews across 25 schools to examine how the frequency of interactions and trust/comfort between students and SROs relate to disciplinary outcomes and feelings of safety. We found no evidence that, in this context, more frequent interactions or differing trust/comfort with SROs increased disciplinary consequences, perhaps because, as students report, SROs tended to not engage in formal discipline. We found that, although SROs were seen as increasing safety, interactions with SROs may have heightened students' sense of danger, potentially mitigating any benefit to students' overall feelings of safety. Implications for use of SROs are discussed.

Published
2021
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25. School-Related Outcomes Associated with Seeing Someone Shot: Do Friends Make a Difference?

Author

Fisher, Benjamin W., Turanovic, Jillian J., and Benitez, Ivan

Abstract

Witnessing violence can negatively affect students' outcomes, but their friendships may mitigate those effects. This study investigated the extent to which seeing someone shot in the last year related to seven school-related outcomes. Additionally, it examined the extent to which prosocial and deviant friends moderate these relationships. This study used data from three waves of the LONGSCAN study (N = 962), employing a series of student fixed effects models to estimate the relationships of interest. This study found no evidence that seeing someone shot in the last year was related to changes in school-related outcomes. Limited evidence of a moderating effect of friends was present, although in unexpected directions. The findings suggest that the effects of childhood trauma are complex and point to the need for a context-specific understanding of exposure to gun violence.

Published
2021
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26. Missed Connections: Examining the Link between Exposure to School Security and Students' Sense of Connectedness to School

Author

National Institute of Justice (NIJ) (DOJ), Fisher, Benjamin W., and Cuellar, Matthew J.

Abstract

School security measures have become commonplace in recent years. Still, little quantitative research has examined how this trend shapes students' perceptions of school. This study examines how students' exposure to school security relates to their sense of school connectedness, with particular attention to the difference between white and nonwhite students. Using a longitudinal sample of 359 students across eight high schools in one urban school district, this study uses student fixed-effects models to link changes in students' exposure to security and connectedness with teachers, peers, and the school. Increases in students' exposure to security were associated with small decreases in students' connectedness to peers, and this association differed for white and nonwhite students. There was no significant association between exposure to security and connectedness with teachers or the school. Increased exposure to school security has limited consequences for within-person changes in school connectedness; however, between-person differences may still exist.

Published
2021
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27. An Examination of School Resource Officers as an Approach to Reduce Social Disturbances in Schools: Evidence from a National Longitudinal Study

Author

Devlin, Deanna N. and Fisher, Benjamin W.

Abstract

School safety is a priority for school administrators and policy makers as they seek strategies to provide an environment conducive to learning. Beyond preventing crime, schools must contend with social disturbances that may not rise to the level of criminal activity, but can negatively affect students, teachers, and the school environment. One approach to addressing social disturbances in schools may be the implementation of sworn police officers called school resource officers (SROs). The purpose of the current study is to evaluate the effectiveness of SROs as an approach to reducing social disturbances in schools by investigating whether varying SRO role approaches have differential impacts. Further, this study seeks to mitigate limitations of previous SRO research influenced by detection effects by focusing on the perceived frequency of social disturbances. Specifically, this study seeks to answer the following research question: What is the relationship between implementing SROs with different role profiles and school administrator's perceptions of the frequency of (1) student racial/ethnic tensions, (2) student bullying, (3) widespread disorder in classrooms, and (4) student gang activities? The data used in this study come from restricted use versions of multiple waves of the School Survey on Crime and Safety (SSOCS), a nationally representative cross-sectional survey completed by school administrators (e.g., principals). This study drew on data from the 2003-04, 2005-06, 2007-08, and 2009-10 versions of the SSOCS. The findings of this study indicated that Full Triad SROs may help decrease bullying, but most SRO roles have no effect or even exacerbate social disturbances. If SROs continue to be implemented, they should avoid engaging in purely law enforcement functions but rather participate in supplemental activities that will foster positive relationships with students.

Published
2021
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28. Disciplinary Disparities by Race and Disability: Using DisCrit Theory to Examine the Manifestation Determination Review Process in Special Education in the United States

Author

Fisher, Amy E., Fisher, Benjamin W., and Railey, Kirsten S.

Abstract

Exclusionary discipline practices in the United States are used disproportionately in the punishment of Black students with a disability compared to White and Black students with or without a disability. One potential mechanism leading to the disproportionate use of exclusionary discipline is a process called 'manifestation determination reviews' (MDR), a process mandated under the U.S. federal Individuals with Disabilities Act that is tasked with determining whether students' offending behaviours were related to their disability. Using a disability studies/critical race theory (DisCrit) lens, the MDR process can be understood as a mechanism that serves to sustain these inequities through vague guidance in critical elements of the MDR process, lack of clarity about the composition of the MDR team, and perpetuation of a race-neutral framework. Implications for policy, educators, and school psychologists within the United States are discussed.

Published
2021
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29. Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases

Author

Korsunsky, Ilya, Wei, Kevin, Pohin, Mathilde, Kim, Edy Y., Barone, Francesca, Major, Triin, Taylor, Emily, Ravindran, Rahul, Kemble, Samuel, Watts, Gerald F.M., Jonsson, A. Helena, Jeong, Yunju, Athar, Humra, Windell, Dylan, Kang, Joyce B., Friedrich, Matthias, Turner, Jason, Nayar, Saba, Fisher, Benjamin A., Raza, Karim, Marshall, Jennifer L., Croft, Adam P., Tamura, Tomoyoshi, Sholl, Lynette M., Vivero, Marina, Rosas, Ivan O., Bowman, Simon J., Coles, Mark, Frei, Andreas P., Lassen, Kara, Filer, Andrew, Powrie, Fiona, Buckley, Christopher D., Brenner, Michael B., and Raychaudhuri, Soumya

Published
2022
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30. Immunofibroblasts regulate LTα3 expression in tertiary lymphoid structures in a pathway dependent on ICOS/ICOSL interaction

Author

Nayar, Saba, Pontarini, Elena, Campos, Joana, Berardicurti, Onorina, Smith, Charlotte G., Asam, Saba, Gardner, David H., Colafrancesco, Serena, Lucchesi, Davide, Coleby, Rachel, Chung, Ming-May, Iannizzotto, Valentina, Hunter, Kelly, Bowman, Simon J., Carlesso, Gianluca, Herbst, Ronald, McGettrick, Helen M., Browning, Jeff, Buckley, Christopher D., Fisher, Benjamin A., Bombardieri, Michele, and Barone, Francesca

Published
2022
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31. Casemix, management, and mortality of patients receiving emergency neurosurgery for traumatic brain injury in the Global Neurotrauma Outcomes Study: a prospective observational cohort study

Author

Abbas, Ghayur, Abdallah, Omar Ibrahim, Abdel-Lateef, Ahmed, Abdifatah, Khalif, Abdullateef, Awfa, Abeygunaratne, Ruvini, Aboellil, Mostafa, Adam, Abass, Adams, Robert, Adeleye, Amos, Adeolu, Augustine, Adji, Novan Krisno, Afianti, Nur, Agarwal, Sudarsan, Aghadi, Ifeanyi Kene, Aguilar, Paúl Martín Méndez, Ahmad, Syeda Rida, Ahmed, Daniyal, Ahmed, Nafees, Aizaz, Haider, Aji, Yunus Kuntawi, Alamri, Alex, Alberto, Augusto Jacinto Mussindo, Alcocer, Luis Alcocer, Alfaro, Lesly Gonzales, Al-Habib, Amro, Alhourani, Ahmad, Ali, Syed Muhammad Rafay, Alkherayf, Fahad, AlMenabbawy, Ahmed, Alshareef, Aliyah, Aminullah, Muhammad Adil s/o, Amjad, Madeha, Amorim, Robson Luis Oliveira de, Anbazhagan, Sathiaprabhu, Andrade, Almir, Antar, Waleed, Anyomih, Theophilus T.K., Aoun, Salah, Apriawan, Tedy, Armocida, Daniele, Arnold, Paul, Arraez, Miguel, Assefa, Temesgen, Asser, Andres, Athiththan, S.P., Attanayake, Deepal, Aung, Maung Maung, Avi, Allan, Ayala, Victor Enrique Antolinez, Azab, Mohammed, Azam, Gaousul, Azharuddin, Mohd, Badejo, Olukemi, Badran, Mohamed, Baig, Azam Ali, Baig, Rehman Ali, Bajaj, Ankur, Baker, Paul, Bala, Renu, Balasa, Artur, Balchin, Ross, Balogun, James, Ban, Vin Shen, Bandi, Bharath Kumar Reddy, Bandyopadhyay, Soham, Bank, Matthew, Barthelemy, Ernest, Bashir, Mohammed Talha, Basso, Luciano Silveira, Basu, Surajit, Batista, Auricelio, Bauer, Marlies, Bavishi, Devi, Beane, Abi, Bejell, Shmuel, Belachew, Anteneh, Belli, Antonio, Belouaer, Amani, Bendahane, Najia El Abbadi, Benjamin, Okanga, Benslimane, Youssef, Benyaiche, Chaymae, Bernucci, Claudio, Berra, Luigi Valentino, Bhebe, Arnold, Bimpis, Alexios, Blanaru, Diana, Bonfim, Jean Claude, Borba, Luis A B, Borcek, Alp Ozgun, Borotto, Erika, Bouhuwaish, Ahmad Elmabri Mohammad, Bourilhon, Facundo, Brachini, Gioia, Breedon, Joshua, Broger, Maximilian, Brunetto, Giacoma Maria Floriana, Bruzzaniti, Placido, Budohoska, Natalia, Burhan, Hira, Calatroni, Maximiliano Luis, Camargo, Catherine, Cappai, Pier Francesco, Cardali, Salvatore Massimiliano, Castaño-Leon, Ana M, Cederberg, David, Celaya, Mikel, Cenzato, Marco, Challa, Lakshmi Madhavi, Charest, Dhanny, Chaurasia, Bipin, Chenna, Rabah, Cherian, Iype, Ching'o, Juliana Henry, Chotai, Tejas, Choudhary, Ajay, Choudhary, Nabeel, Choumin, Florence, Cigic, Tomislav, Ciro, Juan, Conti, Carlo, Corrêa, Antônio Carlos de Souza, Cossu, Giulia, Couto, Maíra Piani, Cruz, Aurora, D'Silva, Divya, D'Aliberti, Giuseppe Antonio, Dampha, Lamin, Daniel, Roy Thomas, Dapaah, Andrew, Darbar, Aneela, Dascalu, Gabriel, Dauda, Happy Amos, Davies, Owain, Delgado-Babiano, Andrea, Dengl, Markus, Despotovic, Marko, Devi, Indira, Dias, Celeste, Dirar, Mohamed, Dissanayake, Melina, Djimbaye, Hananiah, Dockrell, Simon, Dolachee, Ali, Dolgopolova, Julija, Dolgun, Muge, Dow, Abdalrouf, Drusiani, Davide, Dugan, Artjom, Duong, Dinh Tuan, Duong, Trung Kien, Dziedzic, Tomasz, Ebrahim, Ali, El Fatemi, Nizar, El Helou, Antonios El, El Maaqili, Rachid El, El Mostarchid, Brahim El, El Ouahabi, Abdessamad El, Elbaroody, Mohammad, El-Fiki, Ahmed, El-Garci, Ahmed, El-Ghandour, Nasser M.F., Elhadi, Muhammed, Elleder, Vanessa, Elrais, Safa, El-shazly, Mohamed, Elshenawy, Mohamed, Elshitany, Hesham, El-Sobky, Omar, Emhamed, Marwa, Enicker, Basil, Erdogan, Onur, Ertl, Sebastian, Esene, Ignatius, Espinosa, Omar Ocampo, Fadalla, Tarig, Fadelalla, Mohammed, Faleiro, Rodrigo Moreira, Fatima, Nida, Fawaz, Charbel, Fentaw, Assefa, Fernandez, Carla Eiriz, Ferreira, Ana, Ferri, Francesco, Figaji, Tony, Filho, Emerson L B, Fin, Loic, Fisher, Benjamin, Fitra, Fitra, Flores, Alexis Palpan, Florian, Ioan Stefan, Fontana, Vincenzo, Ford, Lauren, Fountain, Daniel, Frade, Jose Maria Roda, Fratto, Antonio, Freyschlag, Christian, Gabin, Aranzazu Sánchez, Gallagher, Clare, Ganau, Mario, Gandia-Gonzalez, Maria Luisa, Garcia, Andoni, Garcia, Borja Hernandez, Garusinghe, Sanjeewa, Gebreegziabher, Biniam, Gelb, Adrian, George, Jerome St, Germanò, Antonino Francesco, Ghetti, Ilaria, Ghimire, Prajwal, Giammarusti, Alessandro, Gil, Jose Luis, Gkolia, Panagiota, Godebo, Yoseph, Gollapudi, Prakash Rao, Golubovic, Jagos, Gomes, Jeremias Fernando, Gonzales, Javier, Gormley, William, Gots, Alexander, Gribaudi, Giulia Letizia, Griswold, Dylan, Gritti, Paolo, Grobler, Ruan, Gunawan, Rudy, Hailemichael, Birhanu, Hakkou, Elmehdi, Haley, Mark, Hamdan, Alhafidz, Hammed, Ali, Hamouda, Waeel, Hamzah, Nurul Ashikin, Han, Nyein Latt, Hanalioglu, Sahin, Haniffa, Rashan, Hanko, Martin, Hanrahan, John, Hardcastle, Timothy, Hassani, Fahd Derkaoui, Heidecke, Volkmar, Helseth, Eirik, Hernández-Hernández, Miguel Ángel, Hickman, Zachary, Hoang, Le Minh Chau, Hollinger, Alexa, Horakova, Lenka, Hossain-Ibrahim, Kismet, Hou, Boru, Hoz, Samer, Hsu, Janine, Hunn, Martin, Hussain, Madiha, Iacopino, Giorgia, Ideta, Mylena Miki Lopes, Iglesias, Irene, Ilunga, Ali, Imtiaz, Nafiz, Islam, Rafiza, Ivashchenko, Serge, Izirouel, Karim, Jabal, Mohamed Sobhi, Jabal, Soubhi, Jabang, John Nute, Jamjoom, Aimun, Jan, Irfan, Jarju, Landing BM, Javed, Saad, Jelaca, Bojan, Jhawar, Sukhdeep Singh, Jiang, Ting Ting, Jimenez, Fernando, Jiris, Jorge, Jithoo, Ron, Johnson, Walt, Joseph, Mathew, Joshi, Rameshman, Junttila, Eija, Jusabani, Mubashir, Kache, Stephen Akau, Kadali, Satyavara Prasad, Kalkmann, Gabriela F, Kamboh, Usman, Kandel, Hitham, Karakus, Ahmet Kamil, Kassa, Mengistu, Katila, Ari, Kato, Yoko, Keba, Martin, Kehoe, Kristy, Kertmen, Huseyin Hayri, Khafaji, Soha, Khajanchi, Monty, Khan, Mohammed, Khan, Muhammad Mukhtar, Khan, Sohail Daud, Khizar, Ahtesham, Khriesh, Amir, Kierońska, Sara, Kisanga, Paul, Kivevele, Boniface, Koczyk, Kacper, Koerling, Anna-Lucia, Koffenberger, Danielle, Kõiv, Kennet, Kõiv, Leho, Kolarovszki, Branislav, König, Marton, Könü-Leblebicioglu, Dilek, Koppala, Santhoshi Devi, Korhonen, Tommi, Kostkiewicz, Boguslaw, Kostyra, Kacper, Kotakadira, Srinivas, Kotha, Arjun Reddy, Kottakki, Madhu Narayana Rao, Krajcinovic, Nenad, Krakowiak, Michal, Kramer, Andreas, Krishnamoorthy, Selvamuthukumaran, Kumar, Ashok, Kumar, Pankaj, Kumar, Pradhumna, Kumarasinghe, Nilaksha, Kuncha, Gowtham, Kutty, Raja K., Laeke, Tsegazeab, Lafta, Ghazwan, Lammy, Simon, Lapolla, Pierfrancesco, Lardani, Jacopo, Lasica, Nebojsa, Lastrucci, Giancarlo, Launey, Yoann, Lavalle, Laura, Lawrence, Tim, Lazaro, Albert, Lebed, Vitalii, Leinonen, Ville, Lemeri, Lawrence, Levi, Leon, Lim, Jia Yi, Lim, Xiao Yi, Linares-Torres, Jorge, Lippa, Laura, Lisboa, Lurdes, Liu, Jinfang, Liu, Ziyuan, Lo, William B, Lodin, Jan, Loi, Federico, Londono, Daniella, Lopez, Pedro Antonio Gomez, López, Cristina Barceló, Lotbiniere-Bassett, Madeleine De, Lulens, Rihards, Luna, Facundo Hector, Luoto, Teemu, M.V., Vijaya Sekhar, Mabovula, Ndyebo, MacAllister, Matthew, Macie, Alcina Americo, Maduri, Rodolfo, Mahfoud, Moufid, Mahmood, Ashraf, Mahmoud, Fathia, Mahoney, Dominic, Makhlouf, Wissam, Malcolm, George, Malomo, Adefolarin, Malomo, Toluyemi, Mani, Manoranjitha Kumari, Marçal, Tomás Gazzinelli, Marchello, Jacopo, Marchesini, Nicolò, Marhold, Franz, Marklund, Niklas, Martín-Láez, Rubén, Mathaneswaran, Vickneswaran, Mato-Mañas, David José, Maye, Helen, McLean, Aaron Lawson, McMahon, Catherine, Mediratta, Saniya, Mehboob, Mehreen, Meneses, Alisson, Mentri, Nesrine, Mersha, Hagos, Mesa, Ana Milena, Meyer, Cristy, Millward, Christopher, Mimbir, Salomao Amone, Mingoli, Andrea, Mishra, Parashruram, Mishra, Tejesh, Misra, Basant, Mittal, Siddharth, Mohammed, Imran, Moldovan, Ioana, Molefe, Masechaba, Moles, Alexis, Moodley, Preston, Morales, Mario Augusto Narváez, Morgan, Lucy, Morillo, German Del Castillo, Moustafa, Wahab, Moustakis, Nikolaos, Mrichi, Salma, Munjal, Satya Shiva, Muntaka, Abdul-Jalilu Mohammed, Naicker, Denver, Nakashima, Paulo E H, Nandigama, Pratap Kumar, Nash, Samantha, Negoi, Ionut, Negoita, Valetina, Neupane, Samundra, Nguyen, Manh Hung, Niantiarno, Fajar Herbowo, Noble, Abbi, Nor, Mohd Arman Muhamad, Nowak, Blazej, Oancea, Andrei, O'Brien, Frazer, Okere, Oghenekevwe, Olaya, Sandra, Oliveira, Leandro, Oliveira, Louise Makarem, Omar, Fatma, Ononeme, Okezi, Opšenák, René, Orlandini, Simone, Osama, Alrobah, Osei-Poku, Dorcas, Osman, Haytham, Otero, Alvaro, Ottenhausen, Malte, Otzri, Shuli, Outani, Oumaima, Owusu, Emmanuel Abem, Owusu-Agyemang, Kevin, Ozair, Ahmad, Ozoner, Baris, Paal, Elli, Paiva, Mauro Sérgio, Paiva, Wellingson, Pandey, Sharad, Pansini, Gastone, Pansini, Luigi, Pantel, Tobias, Pantelas, Nikolaos, Papadopoulos, Konstantinos, Papic, Vladimir, Park, Kee, Park, Nick, Paschoal, Eric Homero Albuquerque, Paschoalino, Mylla Christie de Oliveira, Pathi, Rajesh, Peethambaran, Anilkumar, Pereira, Thiago Andrade, Perez, Irene Panero, Pérez, Claudio José Piqueras, Periyasamy, Tamilanandh, Peron, Stefano, Phillips, Michael, Picazo, Sofía Sotos, Pinar, Ertugrul, Pinggera, Daniel, Piper, Rory, Pirakash, Pathmanesan, Popadic, Branko, Posti, Jussi P., Prabhakar, Rajmohan Bhanu, Pradeepan, Sivanesalingam, Prasad, Manjunath, Prieto, Paola Calvachi, Prince, Ron, Prontera, Andrea, Provaznikova, Eva, Quadros, Danilo, Quintero, Nezly Jadid Romero, Qureshi, Mahmood, Rabiel, Happiness, Rada, Gabriel, Ragavan, Sivagnanam, Rahman, Jueria, Ramadhan, Omar, Ramaswamy, Padma, Rashid, Sakina, Rathugamage, Jagath, Rätsep, Tõnu, Rauhala, Minna, Raza, Asif, Reddycherla, Naga Raju, Reen, Linus, Refaat, Mohamed, Regli, Luca, Ren, Haijun, Ria, Antonio, Ribeiro, Thales Francisco, Ricci, Alessandro, Richterová, Romana, Ringel, Florian, Robertson, Faith, Rocha, Catarina Mayrink Siqueira Cabral, Rogério, Juvenal de Souza, Romano, Adan Anibal, Rothemeyer, Sally, Rousseau, Gail Rousseau Gail, Roza, Ranette, Rueda, Kevin David Farelo, Ruiz, Raiza, Rundgren, Malin, Rzeplinski, Radoslaw, S.Chandran, Raj, Sadayandi, Ramesh Andi, Sage, William, Sagerer, André Norbert Josef, Sakar, Mustafa, Salami, Mohcine, Sale, Danjuma, Saleh, Youssuf, Sánchez-Viguera, Cristina, Sandila, Saning'o, Sanli, Ahmet Metin, Santi, Laura, Santoro, Antonio, Santos, Aieska Kellen Dantas Dos, Santos, Samir Cezimbra dos, Sanz, Borja, Sapkota, Shabal, Sasidharan, Gopalakrishnan, Sasillo, Ibrahim, Satoskar, Rajeev, Sayar, Ali Caner, Sayee, Vignesh, Scheichel, Florian, Schiavo, Felipe Lourenzon, Schupper, Alexander, Schwarz, Andreas, Scott, Teresa, Seeberger, Esther, Segundo, Claudionor Nogueira Costa, Seidu, Anwar Sadat, Selfa, Antonio, Selmi, Nazan Has, Selvarajah, Claudiya, Şengel, Necmiye, Seule, Martin, Severo, Luiz, Shah, Purva, Shahzad, Muhammad, Shangase, Thobekile, Sharma, Mayur, Shiban, Ehab, Shimber, Emnet, Shokunbi, Temitayo, Siddiqui, Kaynat, Sieg, Emily, Siegemund, Martin, Sikder, Shahidur Rahman, Silva, Ana Cristina Veiga, Silva, Ana, Silva, Pedro Alberto, Singh, Deepinder, Skadden, Carly, Skola, Josef, Skouteli, Eirini, Słoniewski, Pawel, Smith, Brandon, Solanki, Guirish, Solla, Davi Fontoura, Solla, Davi, Sonmez, Ozcan, Sönmez, Müge, Soon, Wai Cheong, Stefini, Roberto, Stienen, Martin Nikolaus, Stoica, Bogdan, Stovell, Matthew, Suarez, Maria Natalia, Sulaiman, Alaa, Suliman, Mazin, Sulistyanto, Adi, Sulubulut, Şeniz, Sungailaite, Sandra, Surbeck, Madlen, Szmuda, Tomasz, Taddei, Graziano, Tadele, Abraham, Taher, Ahmed Saleh Ahmed, Takala, Riikka, Talari, Krishna Murthy, Tan, Bih Huei, Tariciotti, Leonardo, Tarmohamed, Murad, Taroua, Oumayma, Tatti, Emiliano, Tenovuo, Olli, Tetri, Sami, Thakkar, Poojan, Thango, Nqobile, Thatikonda, Satish Kumar, Thesleff, Tuomo, Thomé, Claudius, Thornton, Owen, Timmons, Shelly, Timoteo, Eva Ercilio, Tingate, Campbell, Tliba, Souhil, Tolias, Christos, Toman, Emma, Torres, Ivan, Torres, Luis, Touissi, Youness, Touray, Musa, Tropeano, Maria Pia, Tsermoulas, Georgios, Tsitsipanis, Christos, Turkoglu, Mehmet Erhan, Uçkun, Özhan Merzuk, Ullman, Jamie, Ungureanu, Gheorghe, Urasa, Sarah, Ur-Rehman, Obaid, Uysal, Muhammed, Vakis, Antonios, Valeinis, Egils, Valluru, Vaishali, Vannoy, Debby, Vargas, Pablo, Varotsis, Phillipos, Varshney, Rahul, Vats, Atul, Veljanoski, Damjan, Venturini, Sara, Verma, Abhijit, Villa, Clara, Villa, Genaro, Villar, Sofia, Villard, Erin, Viruez, Antonio, Voglis, Stefanos, Vulekovic, Petar, Wadanamby, Saman, Wagner, Katherine, Walshe, Rebecca, Walter, Jan, Waseem, Marriam, Whitworth, Tony, Wijeyekoon, Ruwani, Williams, Adam, Wilson, Mark, Win, Sein, Winarso, Achmad Wahib Wahju, Ximenes, Abraão Wagner Pessoa, Yadav, Anurag, Yadav, Dipak, Yakoub, Kamal Makram, Yalcinkaya, Ali, Yan, Guizhong, Yaqoob, Eesha, Yepes, Carlos, Yılmaz, Ayfer Nazmiye, Yishak, Betelehem, Yousuf, Farhat Basheer, Zahari, Muhammad Zamzuri, Zakaria, Hussein, Zambonin, Diego, Zavatto, Luca, Zebian, Bassel, Zeitlberger, Anna Maria, Zhang, Furong, Zheng, Fengwei, Ziga, Michal, Clark, David, Joannides, Alexis, Adeleye, Amos Olufemi, Bajamal, Abdul Hafid, Bashford, Tom, Biluts, Hagos, Budohoski, Karol, Ercole, Ari, Fernández-Méndez, Rocío, Figaji, Anthony, Gupta, Deepak Kumar, Härtl, Roger, Iaccarino, Corrado, Khan, Tariq, Rubiano, Andrés, Shabani, Hamisi K, Sichizya, Kachinga, Tewari, Manoj, Tirsit, Abenezer, Thu, Myat, Tripathi, Manjul, Trivedi, Rikin, Devi, Bhagavatula Indira, Servadei, Franco, Menon, David, Kolias, Angelos, and Hutchinson, Peter

Published
2022
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32. Namilumab or infliximab compared with standard of care in hospitalised patients with COVID-19 (CATALYST): a randomised, multicentre, multi-arm, multistage, open-label, adaptive, phase 2, proof-of-concept trial

Author

Williams, Bryan, Turner, Rebecca, Libri, Vincenzo, Mussai, Francis, Middleton, Gary, Bowden, Sarah, Bangash, Mansoor, Gao-Smith, Fang, Patel, Jaimin, Sapey, Elizabeth, Thomas, Mark, Coles, Mark, Watkinson, Peter, Rahman, Naj, Angus, Brian, Mentzer, Alexander J., Novak, Alex, Feldman, Marc, Richter, Alex, Faustini, Sian, Bathurst, Camilla, Van de Wiel, Joseph, Mee, Susie, James, Karen, Rahman, Bushra, Turner, Karen, Hill, Adam, Gordon, Anthony, Yap, Christina, Matthay, Michael, McAuley, Danny, Hall, Andrew, Dark, Paul, McMichael, Andrew, Fisher, Benjamin A, Veenith, Tonny, Slade, Daniel, Gaskell, Charlotte, Rowland, Matthew, Whitehouse, Tony, Scriven, James, Parekh, Dhruv, Balasubramaniam, Madhu S, Cooke, Graham, Morley, Nick, Gabriel, Zoe, Wise, Matthew P, Porter, Joanna, McShane, Helen, Ho, Ling-Pei, Newsome, Philip N, Rowe, Anna, Sharpe, Rowena, Thickett, David R, Bion, Julian, Gates, Simon, Richards, Duncan, and Kearns, Pamela

Published
2022
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33. Safety and efficacy of subcutaneous ianalumab (VAY736) in patients with primary Sjögren's syndrome: a randomised, double-blind, placebo-controlled, phase 2b dose-finding trial

Author

Bowman, Simon J, Fox, Robert, Dörner, Thomas, Mariette, Xavier, Papas, Athena, Grader-Beck, Thomas, Fisher, Benjamin A, Barcelos, Filipe, De Vita, Salvatore, Schulze-Koops, Hendrik, Moots, Robert J, Junge, Guido, Woznicki, Janice N, Sopala, Monika A, Luo, Wen-Lin, and Hueber, Wolfgang

Published
2022
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34. Police in Schools and Student Arrest Rates across the United States: Examining Differences by Race, Ethnicity, and Gender

Author

Homer, Emily M. and Fisher, Benjamin W.

Abstract

Implementing police in schools is a common strategy for ensuring school safety, but it is unknown whether, to what extent, and for whom the presence of police in schools affects student arrest rates. Utilizing nationwide data from the 2013-2014 Civil Rights Data Collection (N = 92,620), this study examines how police presence is related to student arrest rates, and whether this association varies by student race/ethnicity and gender. Path models and propensity score matching models show that the association between police presence and arrest rates was stronger for all the groups examined in schools with police, particularly for Black students and boys. This provides support for criminalization theories suggesting that police presence results in more arrests.

Published
2020
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35. Mass School Shootings and the Short-Run Impacts on Use of School Security Measures and Practices: National Evidence from the Columbine Tragedy

Author

Curran, F. Chris, Fisher, Benjamin W., and Viano, Samantha L.

Abstract

Following high-profile school shootings, policymakers and educators seek ways to prevent such shootings, but there has been little research on school-level responses in the immediate aftermath of such events. This study examines how school-level security measures and practices changed after the 1999 Columbine shooting using a nationally representative sample of elementary school principals from the Early Childhood Longitudinal Study (N = 810). Exploiting variation in the timing of survey completion relative to the Columbine shooting, we used regression analysis to examine the use of seven security measures and practices before and after Columbine. Elementary schools were 16 percentage points more likely to lock exits after Columbine and, over time, were more likely to use visitor sign in procedures. School racial/ethnic composition had a moderating effect in some models. Implications for policy and schools are discussed.

Published
2020
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37. Executive summary: British Society for Rheumatology guideline on management of adult and juvenile onset Sjögren disease

Author

Price, Elizabeth J, primary, Benjamin, Stuart, additional, Bombardieri, Michele, additional, Bowman, Simon, additional, Carty, Sara, additional, Ciurtin, Coziana, additional, Crampton, Bridget, additional, Dawson, Annabel, additional, Fisher, Benjamin A, additional, Giles, Ian, additional, Glennon, Peter, additional, Gupta, Monica, additional, Hackett, Katie L, additional, Larkin, Genevieve, additional, Ng, Wan-Fai, additional, Ramanan, Athimalaipet V, additional, Rassam, Saad, additional, Rauz, Saaeha, additional, Smith, Guy, additional, Sutcliffe, Nurhan, additional, Tappuni, Anwar, additional, and Walsh, Stephen B, additional

Published
2024
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38. British Society for Rheumatology guideline on management of adult and juvenile onset Sjögren disease

Author

Price, Elizabeth J, primary, Benjamin, Stuart, additional, Bombardieri, Michele, additional, Bowman, Simon, additional, Carty, Sara, additional, Ciurtin, Coziana, additional, Crampton, Bridget, additional, Dawson, Annabel, additional, Fisher, Benjamin A, additional, Giles, Ian, additional, Glennon, Peter, additional, Gupta, Monica, additional, Hackett, Katie L, additional, Larkin, Genevieve, additional, Ng, Wan-Fai, additional, Ramanan, Athimalaipet V, additional, Rassam, Saad, additional, Rauz, Saaeha, additional, Smith, Guy, additional, Sutcliffe, Nurhan, additional, Tappuni, Anwar, additional, and Walsh, Stephen B, additional

Published
2024
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40. Safety and efficacy of subcutaneous iscalimab (CFZ533) in two distinct populations of patients with Sjögren's disease (TWINSS): week 24 results of a randomised, double-blind, placebo-controlled, phase 2b dose-ranging study

Author

Fisher, Benjamin A, Mariette, Xavier, Papas, Athena, Grader-Beck, Thomas, Bootsma, Hendrika, Ng, Wan-Fai, van Daele, P L A, Finzel, Stephanie, Noaiseh, Ghaith, Elgueta, Sergio, Hermann, Josef, McCoy, Sara S, Akpek, Esen, Bookman, Arthur, Sopala, Monika, Montecchi-Palmer, Michela, Luo, Wen-Lin, Scheurer, Cornelia, Hueber, Wolfgang, Maid, Pablo, Rillo, Oscar, Inderjeeth, Charles, Scheinecker, Clemens, Hermann, Josef, Marcolino, Flora Maria D'Andrea, Dias, Laiza H, Scafuto, Antonio, Bookman, Arthur AM, Fortin, Isabelle, Morin, Frederic, Goio, Elizabeth Jean Moreno, Pezo Ruiz, Ninette, Roman Zamoran, Carlos Patricio, Gonzalez Abarzua, Ivan Antonio, Elgueta, Sergio Fabian, Forero Illera, Elias Gonzalo, Marquez Herndez, Javier Dario, Garcia, Alex Echeverri, Pensec, Valerie Devauchelle, Hachulla, Eric, Mariette, Xavier, Gottenberg, Jacques-Eric, Le Guern, Veronique, Finzel, Stephanie, Schaefer, Valentin, Tony, Hans-Peter, Thomas Schmalzing, Marc, Tausche-Wunderlich, Anne-Kathrin, Tzioufas, Athanasios, Balog, Attila, Rojkovich, Bernadette, Varga, Tunde, Lidar, Merav, Rosner, Itzhak, Levy, Yair, Dagna, Lorenzo, Mosca, Marta, Quartuccio, Luca, Nishiyama, Susumu, Kodera, Masanari, Kaneko, Yuko, Okada, Masato, Ueki, Yukitaka, Hwan Park, Sung, van Daele, Paulus Leon Arthur, Bootsma, Hendrika, Duarte Barcelos, Filipe Alexandre, Crispim Romao, Vasco Madeira, Raimundo Vinagre, Filipe Manuel, Tavaresda Costa, Jose Antonio, Rednic, Simona, Duca, Liliana, Maslyanskiy, Alexey, Yakupova, Svetlana, Bugrova, Olga, Izmozherova, Nadezhda, Zotkin, Evgenyi, Nikolaevna Anoshenkova, Olga, Kvarnstrom, Marika, Tufan, Abdurrahman, Fisher, Benjamin, Yee, Chee Seng, Parker, Benjamin Joseph, Grader Beck, Thomas, Lawrence Ford, Theresa, Papas, Athena, Carsons, Steven, Thiagarajan, Saravanan, Zero, Domenick, McCoy, Sara, and Sandorfi, Nora

Abstract

Sjögren's disease is a chronic autoimmune disease with an unmet need for targeted therapies. The aim of the TWINSS study is to evaluate the safety and efficacy of iscalimab, a monoclonal antibody against CD40, in patients with active Sjögren's disease.

Published
2024
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41. Examining School Security Measures as Moderators of the Association between Homophobic Victimization and School Avoidance

Author

Fisher, Benjamin W. and Tanner-Smith, Emily E.

Abstract

Homophobic victimization is a pervasive problem in U.S. schools that leads to negative outcomes for students. Those who experience homophobic victimization are at greater risk for avoiding particular spaces in school because they feel unsafe or afraid. Visible school security measures (e.g., security guards, metal detectors, and cameras) offer spatial guardianship that may reduce students' place-specific avoidance behaviors. To test this moderating effect of school security, we analyzed data from six panels of the School Crime Supplement to the National Crime Victimization Survey (N = 41,229). Logistic regression models were used to examine the moderating effect of three types of school security measures on the association between homophobic victimization and avoidance of six specific locations in school and overall fear of victimization at school. Results suggest that visible security measures did not meaningfully moderate the association between homophobic victimization and school avoidance. [At time of submission to ERIC this article was in press with "Journal of School Violence."]

Published
2015
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42. Visible School Security Measures and Student Academic Performance, Attendance, and Postsecondary Aspirations

Author

Tanner-Smith, Emily E. and Fisher, Benjamin W.

Abstract

Many U.S. schools use visible security measures (security cameras, metal detectors, security personnel) in an effort to keep schools safe and promote adolescents' academic success. This study examined how different patterns of visible security utilization were associated with U.S. middle and high school students' academic performance, attendance, and postsecondary educational aspirations. The data for this study came from two large national surveys--the School Crime Supplement to the National Crime Victimization Survey (N = 38,707 students; 51% male, 77% White, M[subscript Age] = 14.72) and the School Survey on Crime & Safety (N = 10,340 schools; average student composition of 50% male, 57% White). The results provided no evidence that visible security measures had consistent beneficial effects on adolescents' academic outcomes; some security utilization patterns had modest detrimental effects on adolescents' academic outcomes, particularly the heavy surveillance patterns observed in a small subset of high schools serving predominantly low socioeconomic students. The findings of this study provide no evidence that visible security measures have any sizeable effects on academic performance, attendance, or postsecondary aspirations among U.S. middle and high school students. The following are appended: (1) Variables Used in Propensity Score Models (table); and (2) Effects of Visible Security Measures on Academic Outcomes, SCS Student Surveys (N = 38,707) (table). [At time of submission to ERIC this article was in press with "Journal of Youth and Adolescence."]

Published
2015
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45. Examining the biological pathways underlying clinical heterogeneity in Sjogren's syndrome : proteomic and network analysis

Author

Berry, Joe Scott, Tarn, Jessica, Casement, John, Duret, Pierre-Marie, Scott, Lauren, Wood, Karl, Johnsen, Svein-Joar, Nordmark, Gunnel, Devauchelle-Pensec, Valerie, Seror, Raphaele, Fisher, Benjamin, Barone, Fransesca, Bowman, Simon J., Bombardieri, Michele, Lendrem, Dennis, Felten, Renaud, Gottenberg, Jacques-Eric, Ng, Wan-Fai, Berry, Joe Scott, Tarn, Jessica, Casement, John, Duret, Pierre-Marie, Scott, Lauren, Wood, Karl, Johnsen, Svein-Joar, Nordmark, Gunnel, Devauchelle-Pensec, Valerie, Seror, Raphaele, Fisher, Benjamin, Barone, Fransesca, Bowman, Simon J., Bombardieri, Michele, Lendrem, Dennis, Felten, Renaud, Gottenberg, Jacques-Eric, and Ng, Wan-Fai

Abstract

Objectives: Stratification approaches are vital to address clinical heterogeneity in Sjogren's syndrome (SS). We previously described that the Newcastle Sjogren's Stratification Tool (NSST) identified four distinct clinical subtypes of SS. We performed proteomic and network analysis to analyse the underlying pathobiology and highlight potential therapeutic targets for different SS subtypes. Method: We profiled serum proteins using O-link technology of 180 SS subjects. We used 5 O-link proteomics panels which included a total of 454 unique proteins. Network reconstruction was performed using the ARACNE algorithm, with differential expression estimates overlaid on these networks to reveal the key subnetworks of differential expression. Furthermore, data from a phase III trial of tocilizumab in SS were reanalysed by stratifying patients at baseline using NSST. Results: Our analysis highlights differential expression of chemokines, cytokines and the major autoantigen TRIM21 between the SS subtypes. Furthermore, we observe differential expression of several transcription factors associated with energy metabolism and redox balance namely APE1/Ref-1, FOXO1, TIGAR and BACH1. The differentially expressed proteins were inter-related in our network analysis, supporting the concept that distinct molecular networks underlie the clinical subtypes of SS. Stratification of patients at baseline using NSST revealed improvement of fatigue score only in the subtype expressing the highest levels of serum IL-6. Conclusions: Our data provide clues to the pathways contributing to the glandular and non-glandular manifestations of SS and to potential therapeutic targets for different SS subtypes. In addition, our analysis highlights the need for further exploration of altered metabolism and mitochondrial dysfunction in the context of SS subtypes.

Published
2024
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46. The Sjögren's Working Group:The 2023 OMERACT meeting and provisional domain generation

Author

Gordon, Rachael A., Nguyen, Yann, Foulquier, Nathan, Beydon, Maxime, Gheita, Tamer A., Hajji, Raouf, Sahbudin, Ilfita, Hoi, Alberta, Ng, Wan Fai, Mendonça, Jose Alexandre, Wallace, Daniel J., Shea, Beverley, Bruyn, George AW, Goodman, Susan M., Fisher, Benjamin A., Baldini, Chiara, Torralba, Karina D., Bootsma, Hendrika, Akpek, Esen K., Karakus, Sezen, Baer, Alan N., Chakravarty, Soumya D., Terslev, Lene, D'Agostino, Maria Antonietta, Mariette, Xavier, DiRenzo, Dana, Rasmussen, Astrid, Papas, Athena, Montoya, Cristina, Arends, Suzanne, Yusof, Md Yuzaiful Md, Pintilie, Ionut, Warner, Blake M., Hammitt, Katherine M., Strand, Vibeke, Bouillot, Coralie, Tugwell, Peter, Inanc, Nevsun, Andreu, José Luis, Wahren-Herlenius, Marie, Devauchelle-Pensec, Valerie, Shiboski, Caroline H., Benyoussef, Anas, Masli, Sharmila, Lee, Adrian Y.S., Cornec, Divi, Bowman, Simon, Rischmueller, Maureen, McCoy, Sara S., Seror, Raphaele, Gordon, Rachael A., Nguyen, Yann, Foulquier, Nathan, Beydon, Maxime, Gheita, Tamer A., Hajji, Raouf, Sahbudin, Ilfita, Hoi, Alberta, Ng, Wan Fai, Mendonça, Jose Alexandre, Wallace, Daniel J., Shea, Beverley, Bruyn, George AW, Goodman, Susan M., Fisher, Benjamin A., Baldini, Chiara, Torralba, Karina D., Bootsma, Hendrika, Akpek, Esen K., Karakus, Sezen, Baer, Alan N., Chakravarty, Soumya D., Terslev, Lene, D'Agostino, Maria Antonietta, Mariette, Xavier, DiRenzo, Dana, Rasmussen, Astrid, Papas, Athena, Montoya, Cristina, Arends, Suzanne, Yusof, Md Yuzaiful Md, Pintilie, Ionut, Warner, Blake M., Hammitt, Katherine M., Strand, Vibeke, Bouillot, Coralie, Tugwell, Peter, Inanc, Nevsun, Andreu, José Luis, Wahren-Herlenius, Marie, Devauchelle-Pensec, Valerie, Shiboski, Caroline H., Benyoussef, Anas, Masli, Sharmila, Lee, Adrian Y.S., Cornec, Divi, Bowman, Simon, Rischmueller, Maureen, McCoy, Sara S., and Seror, Raphaele

Abstract

Sjögren's disease (SjD) is a systemic autoimmune exocrinopathy with key features of dryness, pain, and fatigue. SjD can affect any organ system with a variety of presentations across individuals. This heterogeneity is one of the major barriers for developing effective disease modifying treatments. Defining core disease domains comprising both specific clinical features and incorporating the patient experience is a critical first step to define this complex disease. The OMERACT SjD Working Group held its first international collaborative hybrid meeting in 2023, applying the OMERACT 2.2 filter toward identification of core domains. We accomplished our first goal, a scoping literature review that was presented at the Special Interest Group held in May 2023. Building on the domains identified in the scoping review, we uniquely deployed multidisciplinary experts as part of our collaborative team to generate a provisional domain list that captures SjD heterogeneity, Sjögren's disease (SjD) is a systemic autoimmune exocrinopathy with key features of dryness, pain, and fatigue. SjD can affect any organ system with a variety of presentations across individuals. This heterogeneity is one of the major barriers for developing effective disease modifying treatments. Defining core disease domains comprising both specific clinical features and incorporating the patient experience is a critical first step to define this complex disease. The OMERACT SjD Working Group held its first international collaborative hybrid meeting in 2023, applying the OMERACT 2.2 filter toward identification of core domains. We accomplished our first goal, a scoping literature review that was presented at the Special Interest Group held in May 2023. Building on the domains identified in the scoping review, we uniquely deployed multidisciplinary experts as part of our collaborative team to generate a provisional domain list that captures SjD heterogeneity.

Published
2024

47. Abatacept in individuals at high risk of rheumatoid arthritis (APIPPRA): a randomised, double-blind, multicentre, parallel, placebo-controlled, phase 2b clinical trial

Author

Cope, Andrew P, Jasenecova, Marianna, Vasconcelos, Joana C, Filer, Andrew, Raza, Karim, Qureshi, Sumera, D'Agostino, Maria Antonietta, Mcinnes, Iain B, Isaacs, John D, Pratt, Arthur G, Fisher, Benjamin A, Buckley, Christopher D, Emery, Paul, Ho, Pauline, Buch, Maya H, Ciurtin, Coziana, van Schaardenburg, Dirkjan, Huizinga, Thoma, Toes, René, Georgiou, Evangelo, Kelly, Joanna, Murphy, Caroline, Prevost, A Toby, Norton, Sam, Lempp, Heidi, Opena, Maria, Subesinghe, Sujith, Garrood, Toby, Menon, Bina, Ng, Nora, Douglas, Karen, Koutsianas, Christo, Cooles, Faye, Falahee, Marie, Echavez-Naguicnic, Irene, Bharadwaj, Anurag, Villaruel, Michael, Pande, Ira, Collins, David, Pegler, Suzannah, Raizada, Sabrina, Siebert, Stefan, Fragoulis, George, Guinto, Jesusa, Galloway, Jame, Rutherford, Andrew, Barnes, Theresa, Jeffrey, Helen, Patel, Yusuf, Batley, Michael, O'Reilly, Brendan, Venkatachalam, Srivinisan, Sheeran, Thoma, Gorman, Claire, Reynolds, Piero, Khan, Asad, Gullick, Nicola, Banerjee, Siwalik, Mankia, Kulveer, Jordan, Deepak, Rowlands, Jane, Starmans-Kool, Mirian, Taylor, Jame, Nandi, Pradip, Sahbudin, Ilfita, Maybury, Mark, Hider, Samantha, Barcroft, Ann, Mcnally, Jeremy, Kitchen, Jo, Nisar, Muhammad, Quick, Vanessa, D'Agostino, Maria Antonietta (ORCID:0000-0002-5347-0060), Cope, Andrew P, Jasenecova, Marianna, Vasconcelos, Joana C, Filer, Andrew, Raza, Karim, Qureshi, Sumera, D'Agostino, Maria Antonietta, Mcinnes, Iain B, Isaacs, John D, Pratt, Arthur G, Fisher, Benjamin A, Buckley, Christopher D, Emery, Paul, Ho, Pauline, Buch, Maya H, Ciurtin, Coziana, van Schaardenburg, Dirkjan, Huizinga, Thoma, Toes, René, Georgiou, Evangelo, Kelly, Joanna, Murphy, Caroline, Prevost, A Toby, Norton, Sam, Lempp, Heidi, Opena, Maria, Subesinghe, Sujith, Garrood, Toby, Menon, Bina, Ng, Nora, Douglas, Karen, Koutsianas, Christo, Cooles, Faye, Falahee, Marie, Echavez-Naguicnic, Irene, Bharadwaj, Anurag, Villaruel, Michael, Pande, Ira, Collins, David, Pegler, Suzannah, Raizada, Sabrina, Siebert, Stefan, Fragoulis, George, Guinto, Jesusa, Galloway, Jame, Rutherford, Andrew, Barnes, Theresa, Jeffrey, Helen, Patel, Yusuf, Batley, Michael, O'Reilly, Brendan, Venkatachalam, Srivinisan, Sheeran, Thoma, Gorman, Claire, Reynolds, Piero, Khan, Asad, Gullick, Nicola, Banerjee, Siwalik, Mankia, Kulveer, Jordan, Deepak, Rowlands, Jane, Starmans-Kool, Mirian, Taylor, Jame, Nandi, Pradip, Sahbudin, Ilfita, Maybury, Mark, Hider, Samantha, Barcroft, Ann, Mcnally, Jeremy, Kitchen, Jo, Nisar, Muhammad, Quick, Vanessa, and D'Agostino, Maria Antonietta (ORCID:0000-0002-5347-0060)

Abstract

Background: Individuals with serum antibodies to citrullinated protein antigens (ACPA), rheumatoid factor, and symptoms, such as inflammatory joint pain, are at high risk of developing rheumatoid arthritis. In the arthritis prevention in the pre-clinical phase of rheumatoid arthritis with abatacept (APIPPRA) trial, we aimed to evaluate the feasibility, efficacy, and acceptability of treating high risk individuals with the T-cell co-stimulation modulator abatacept. Methods: The APIPPRA study was a randomised, double-blind, multicentre, parallel, placebo-controlled, phase 2b clinical trial done in 28 hospital-based early arthritis clinics in the UK and three in the Netherlands. Participants (aged ≥18 years) at risk of rheumatoid arthritis positive for ACPA and rheumatoid factor with inflammatory joint pain were recruited. Exclusion criteria included previous episodes of clinical synovitis and previous use of corticosteroids or disease-modifying antirheumatic drugs. Participants were randomly assigned (1:1) using a computer-generated permuted block randomisation (block sizes of 2 and 4) stratified by sex, smoking, and country, to 125 mg abatacept subcutaneous injections weekly or placebo for 12 months, and then followed up for 12 months. Masking was achieved by providing four kits (identical in appearance and packaging) with pre-filled syringes with coded labels of abatacept or placebo every 3 months. The primary endpoint was the time to development of clinical synovitis in three or more joints or rheumatoid arthritis according to American College of Rheumatology and European Alliance of Associations for Rheumatology 2010 criteria, whichever was met first. Synovitis was confirmed by ultrasonography. Follow-up was completed on Jan 13, 2021. All participants meeting the intention-to-treat principle were included in the analysis. This trial was registered with EudraCT (2013-003413-18). Findings: Between Dec 22, 2014, and Jan 14, 2019, 280 individuals were evaluated for el

Published
2024

48. The Sjögren's Working Group: The 2023 OMERACT meeting and provisional domain generation

Author

Gordon, Rachael A, Nguyen, Yann, Foulquier, Nathan, Beydon, Maxime, Gheita, Tamer A, Hajji, Raouf, Sahbudin, Ilfita, Hoi, Alberta, Ng, Wan-Fai, Mendonça, Jose Alexandre, Wallace, Daniel J, Shea, Beverley, Bruyn, George Aw, Goodman, Susan M, Fisher, Benjamin A, Baldini, Chiara, Torralba, Karina D, Bootsma, Hendrika, Akpek, Esen K, Karakus, Sezen, Baer, Alan N, Chakravarty, Soumya D, Terslev, Lene, D'Agostino, Maria Antonietta, Mariette, Xavier, Direnzo, Dana, Rasmussen, Astrid, Papas, Athena, Montoya, Cristina, Arends, Suzanne, Yusof, Md Yuzaiful Md, Pintilie, Ionut, Warner, Blake M, Hammitt, Katherine M, Strand, Vibeke, Bouillot, Coralie, Tugwell, Peter, Inanc, Nevsun, Andreu, José Lui, Wahren-Herlenius, Marie, Devauchelle-Pensec, Valerie, Shiboski, Caroline H, Benyoussef, Ana, Masli, Sharmila, Lee, Adrian Y S, Cornec, Divi, Bowman, Simon, Rischmueller, Maureen, Mccoy, Sara S, Seror, Raphaele, D'Agostino, Maria-Antonietta (ORCID:0000-0002-5347-0060), Gordon, Rachael A, Nguyen, Yann, Foulquier, Nathan, Beydon, Maxime, Gheita, Tamer A, Hajji, Raouf, Sahbudin, Ilfita, Hoi, Alberta, Ng, Wan-Fai, Mendonça, Jose Alexandre, Wallace, Daniel J, Shea, Beverley, Bruyn, George Aw, Goodman, Susan M, Fisher, Benjamin A, Baldini, Chiara, Torralba, Karina D, Bootsma, Hendrika, Akpek, Esen K, Karakus, Sezen, Baer, Alan N, Chakravarty, Soumya D, Terslev, Lene, D'Agostino, Maria Antonietta, Mariette, Xavier, Direnzo, Dana, Rasmussen, Astrid, Papas, Athena, Montoya, Cristina, Arends, Suzanne, Yusof, Md Yuzaiful Md, Pintilie, Ionut, Warner, Blake M, Hammitt, Katherine M, Strand, Vibeke, Bouillot, Coralie, Tugwell, Peter, Inanc, Nevsun, Andreu, José Lui, Wahren-Herlenius, Marie, Devauchelle-Pensec, Valerie, Shiboski, Caroline H, Benyoussef, Ana, Masli, Sharmila, Lee, Adrian Y S, Cornec, Divi, Bowman, Simon, Rischmueller, Maureen, Mccoy, Sara S, Seror, Raphaele, and D'Agostino, Maria-Antonietta (ORCID:0000-0002-5347-0060)

Abstract

Sjögren's disease (SjD) is a systemic autoimmune exocrinopathy with key features of dryness, pain, and fatigue. SjD can affect any organ system with a variety of presentations across individuals. This heterogeneity is one of the major barriers for developing effective disease modifying treatments. Defining core disease domains comprising both specific clinical features and incorporating the patient experience is a critical first step to define this complex disease. The OMERACT SjD Working Group held its first international collaborative hybrid meeting in 2023, applying the OMERACT 2.2 filter toward identification of core domains. We accomplished our first goal, a scoping literature review that was presented at the Special Interest Group held in May 2023. Building on the domains identified in the scoping review, we uniquely deployed multidisciplinary experts as part of our collaborative team to generate a provisional domain list that captures SjD heterogeneity.

Published
2024

49. Why and When Do School Resource Officers Engage in School Discipline? The Role of Context in Shaping Disciplinary Involvement

Author

Curran, F. Chris, Fisher, Benjamin W., Viano, Samantha, and Kupchik, Aaron

Abstract

The use of law enforcement in schools raises concerns about impacts on school discipline. Drawing on a large-scale qualitative study of approximately fifty schools across two school districts, this study explores school resource officers' (SROs') involvement in school discipline and how it is shaped by their context. We use interview, focus group, and observation data from nearly 200 participants to document variability in the way SROs conceptualize and are involved in discipline as well as how such involvement is shaped by context. Although 79% of SROs initially report not being involved in discipline, we find that the majority involve themselves in nuanced ways that are shaped by relationships with school staff, official policies, and the characteristics of students served. Our results point to the need for clarity around SROs' involvement in discipline and ways that schools can shape contexts to ensure that SROs are not increasing the use of exclusionary practices.

Published
2019
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50. Teacher Victimization, Turnover, and Contextual Factors Promoting Resilience

Author

Curran, F. Chris, Viano, Samantha L., and Fisher, Benjamin W.

Abstract

Teacher victimization is a relatively understudied phenomenon that may contribute to teacher turnover. The purpose of this study is to explore the relationship between teacher reports of victimization and teachers leaving their school and the profession. Using nationally representative data (n = 104,840) from the Schools and Staffing Survey, we examine the extent to which being threatened or attacked by students predicts higher rates of teacher turnover and whether this relationship differs due to factors that may promote teacher resilience. We utilize conditional multinomial logistic regression, implicitly controlling for school-by-year fixed effects. Findings suggest that perceived victimization predicts an increased probability of leaving the school and profession. School-level promoters of resilience are found to lessen this relationship. We discuss ways schools can mitigate the impact of victimization. This work contributes to a nascent body of literature on teacher victimization and informs a policy lever by which turnover may be reduced.

Published
2019
Full Text
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