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1. Interdisciplinary consensus on indications for transfemoral transcatheter aortic valve implantation (TF-TAVI): Joint Consensus Document of the Arbeitsgemeinschaft Leitende Kardiologische Krankenhausärzte e.V. (ALKK) and cooperating Cardiac Surgery Departments

Author

von Scheidt, Wolfgang, Welz, A., Pauschinger, M., Fischlein, T., Schächinger, V., Treede, H., Zahn, R., Hennersdorf, M., Albes, J. M., Bekeredjian, R., Beyer, M., Brachmann, J., Butter, C., Bruch, L., Dörge, H., Eichinger, W., Franke, U. F. W., Friedel, N., Giesler, T., Gradaus, R., Hambrecht, R., Haude, M., Hausmann, H., Heintzen, M. P., Jung, W., Kerber, S., Mudra, H., Nordt, T., Pizzulli, L., Sack, F.-U., Sack, S., Schumacher, B., Schymik, G., Sechtem, U., Stellbrink, C., Stumpf, C., and Hoffmeister, H. M.

Published
2020
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2. Functionality and Outcome in Older Patients with Severe Aortic Stenosis (FOOPAS): an interdisciplinary study concept for a prospective trial

Author

Vogt F, Wicklein S, Gosch M, Jessl J, Hitzl W, Fischlein T, Pauschinger M, Pfeiffer S, and Eckner D

Subjects
Frailty, Aortic Valve, Geriatric Assessment, Transcatheter Aortic Valve Implantation - TAVI, Aortic Valve Replacement - AVR, Geriatrics, RC952-954.6
Abstract

Ferdinand Vogt,1 Susanne Wicklein,2 Markus Gosch,2 Jürgen Jessl,3 Wolfgang Hitzl,4 Theodor Fischlein,1 Matthias Pauschinger,3 Steffen Pfeiffer,1 Dennis Eckner3 1Department of Cardiac Surgery, Paracelsus Medical University, Nuremberg, Germany; 2Department of Geriatric Medicine, Paracelsus Medical University, Nuremberg, Germany; 3Department of Cardiology, Paracelsus Medical University, Nuremberg, Germany; 4Research Office – Biostatistics, Paracelsus Medical University, Salzburg, Austria Background: Frailty is a geriatric syndrome that can influence mortality and functional recovery after treatment of severe aortic stenosis (AS). The integration of standardized geriatric assessment (GA) in clinical practice is limited by a lack of consensus on how to measure it. Objectives: This study aims to compare the incremental predictive value of different frailty scales to predict the outcomes following surgical aortic valve replacement, transcatheter aortic valve implantation, and conservative treatment of severe AS. Methods: A prospective cohort of 300 older adults with severe AS will be assembled after standard clinical examinations and a comprehensive GA, including 18 different tests and values. Primary outcome parameters are overall mortality, cardiovascular mortality, quality of life, and functionality. Secondary parameters are overall complications, cardiovascular complications, and costs. Results: Expected results will contribute to the growing body of evidence on frailty based on parameters that influence clinical and functional outcome in elderly patients independent of the method of treatment. The pre-procedural assessment is expected to be valuable in discriminating new post-procedural complications from simple exacerbations of pre-existing conditions. Therefore, a new frailty test which is simple and feasible for application in a clinical routine by most medical professionals, may help in identifying patients for whom further GA should be considered. Finally, such a frailty score could support heart teams to find the right treatment for patients suffering from AS. Conclusion: Comparison of different frailty scales has not only the goal of finding a predictive value of mortality but also to bring in a meaningful improvement for each individual patient and to avoid disability or fatal outcomes. Keywords: frailty, aortic valve, geriatric assessment, transcatheter aortic valve implantation, TAVI, aortic valve replacement, AVR

Published
2018

3. Utility of Preopeative Computed Tomography Scans for Predicting Long Term Outcomes after Surgical Aortic Valve Replacement.

Author

Pollari, F., Anjileli, A., Hitzl, W., Ledwon, M., Bagaev, E., and Fischlein, T.

Subjects
AORTIC valve transplantation, ON-demand computing, HEART valve prosthesis implantation, AORTIC valve diseases
Abstract

This article discusses the utility of preoperative computed tomography (CT) scans in predicting long-term outcomes after minimally invasive surgical aortic valve replacement (mSAVR). The study analyzed 203 patients who underwent mSAVR and found that certain anatomical variables assessed by preoperative CT were correlated with survival and major cardiac events. The authors conclude that preoperative CT should be included in the preparatory pathway for patients with severe aortic valve disease. [Extracted from the article]

Published
2024
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6. Partial versus Complete Sternotomy for Surgical Aortic Valve Replacement: Results of a Multicenter Study

Author

Göbel, N., additional, Stankowski, T., additional, Pollari, F., additional, Hassan, K., additional, Jückstock, H., additional, Schubel, J., additional, Sellin, C., additional, Zielezinski, T., additional, Elhmidi, Y., additional, Sack, F. U., additional, Feyrer, R., additional, Dörge, H., additional, Hausmann, H., additional, Massoudy, P., additional, Schmoeckel, M., additional, Fischlein, T., additional, Fritzsche, D., additional, and Franke, U., additional

Published
2023
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13. OC87 VALUE OF SCREENING ASYMPTOMATIC CAROTID ARTERY STENOSIS PRIOR TO CORONARY ARTERY BYPASS GRAFTING: ANALYSIS OF THE E-CABG REGISTRY

Author

Salsano, A., Santarpino, G., Santini, F., Nicolini, F., De Feo, M., Dalén, M., Fischlein, T., Perrotti, A., Reichart, D., Gatti, G., Onorati, F., Franzese, I., Faggian, G., Bancone, C., Chocron, S., Khodabandeh, S., Rubino, A.S., Maselli, D., Nardella, S., Gherli, R., Zanobini, M., Saccocci, M., Bounader, K., Rosato, S., Tauriainen, T., Mariscalco, G., Airaksinen, J., Ruggieri, V.G., and Biancari, F.

Published
2018
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14. OC88 COMPARATIVE ANALYSIS OF PROTHROMBIN COMPLEX CONCENTRATE AND FRESH FROZEN PLASMA IN THE MANAGEMENT OF PERIOPERATIVE BLEEDING AFTER CORONARY ARTERY BYPASS GRAFTING

Author

Salsano, A., Mariscalco, G., Santini, F., Ruggieri, V.G., Perrotti, A., Chocron, S., Gherli, R., Reichart, D., Demal, T., Faggian, G., Franzese, I., Dalén, M., Santarpino, G., Fischlein, T., Rubino, A.S., Maselli, D., Nardella, S., Nicolini, F., Saccocci, M., Gatti, G., Bounader, K., Rosato, S., Kinnunen, E., De Feo, M., Tauriainen, T., Onorati, F., and Biancari, F.

Published
2018
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21. Surgical Aortic Valve Replacement in Patients Aged 50 to 69 Years: Insights from the German Aortic Valve Registry (GARY)

Author

Vogt, F., additional, Santarpino, G., additional, Fujita, B., additional, Frerker, C., additional, Bauer, T., additional, Bekeredjian, R., additional, Bleiziffer, S., additional, Beckmann, A., additional, Möllmann, H., additional, Walther, T., additional, Beyersdorf, F., additional, Hamm, C., additional, Böning, A., additional, Baldus, S., additional, Ensminger, S., additional, Fischlein, T., additional, and Eckner, D., additional

Published
2022
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26. Lungenarterienembolie oder ein seltener Fall von Lungenarterien-Ascariasis?

Author

Schuster, I., Kalisnik, J. M., Kubitz, J. C., and Fischlein, T.

Abstract

Copyright of Anaesthesiologie & Intensivmedizin is the property of DGAI e.V. - Deutsche Gesellschaft fur Anasthesiologie und Intensivmedizin e.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2022
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33. Infectious complications in patients receiving ticagrelor or clopidogrel before coronary artery bypass grafting

Author

Dalén, M., primary, Biancari, F., additional, Perrotti, A., additional, Mariscalco, G., additional, Onorati, F., additional, Faggian, G., additional, Franzese, I., additional, Salsano, A., additional, Santini, F., additional, Ruggieri, V.G., additional, Maselli, D., additional, Nardella, S., additional, Santarpino, G., additional, Fischlein, T., additional, Saccocci, M., additional, Zanobini, M., additional, Musumeci, F., additional, Gherli, R., additional, Rubino, A.S., additional, De Feo, M., additional, Bancone, C., additional, Nicolini, F., additional, Kinnunen, E.-M., additional, Tauriainen, T., additional, Reichart, D., additional, Demal, T., additional, Gatti, G., additional, Khodabandeh, S., additional, and Holm, M., additional

Published
2020
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36. Posters

Author

Ŝifrer, Fronc, Drinovec, Igor, Thomson, G., Baker, L., Mawby, E., Leach, R. M., Jensen, P. J., Michagin, G., Andersen, P. K., Peláez, J., Asensio, M. J., Jiménez, M., Yus, S., Villa, P., Vaquero, C., Imhoff, M., Lehner, J. H., Löhlein, D., Vignali, G., Guadagnucci, A., Mariotti, M., Baratta, A., Vignali, A., Rutili, A., Tulli, G., Sanft, C., Spies, C., Oschmann, G., Schaffartzik, W., Gondos, T., Arkosy, M., Jović M., Popović Z., Radomir B., Ilić V., Panić G., Babić M., Popović A., Bojić M., Pierucci, E., Ghermandi, C., Morigi, A., Morgagni, R., Nastasi, M., Rossi, R., Martinelli, G., Faenza, S., Cuccolini, F., Martinelli, G., Sarti, E., O’Hare, B., Betit, P., Thompson, J. E., Wessel, D. L., Kuhn, T. J., Bauer, B. L., Broomhead, C. J., Wright, S. J., Kiff, K. J., Withington, P. S., Strunin, L., Amaral, J. L. G., Rouby, J. -J., Gallart, L., Munechika, M., Coriat, P., Michard, F., Wysocki, M., Millet, H., Wolff, M. A., Herman, B., Peyerl, M., Gödje, O., Fischlein, T., Pfeiffer, U., Reichart, B., Krenn, C. G., Baker, A., Krafft, P., Narzt, E., Spiss, C. K., Steltzer, H., Theilen, H., Ragaller, M., Albrecht, D. M., Llagunes, J., Catala, J. C., Marques, J. I., Pena, J. J., Barbas, D., Aguar, F., Grau, F., Navarrete-Sánchez I., Ruiz-Bailén H., Guerrero-López F., Colmenero-Ruiz H., Fernández-Hondéjar E., Vázquez-Hata G., Lamb, F. J., Rhodes, A., Duane, D., Grounds, R. M., and Bennett, E. D.

Published
1996
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38. Comparative Analysis of Prothrombin Complex Concentrate and Fresh Frozen Plasma in the Management of Perioperative Bleeding after Coronary Artery Bypass Grafting

Author

Salsano, A., Mariscalco, G., Santini, F., Ruggieri, V. G., Perrotti, A., Chocron, S., Gherli, R., Reichart, D., Demal, T., Faggian, G., Franzese, I., Dalén, M., Santarpino, G., Fischlein, T., Rubino, A. S., Maselli, D., Nardella, S., Nicolini, F., Saccocci, M., Gatti, G., Bounader, K., Rosato, S., Kinnunen, E., De Feo, M., Tauriainen, T., Onorati, F., and Biancari, F.

Published
2018

39. Variation in preoperative antithrombotic strategy, severe bleeding, and use of blood products in coronary artery bypass grafting:results from the multicentre E-CABG registry

Author

Biancari, F. (Fausto), Mariscalco, G. (Giovanni), Gherli, R. (Riccardo), Reichart, D. (Daniel), Onorati, F. (Francesco), Faggian, G. (Giuseppe), Franzese, I. (Ilaria), Santarpino, G. (Giuseppe), Fischlein, T. (Theodor), Rubino, A. S. (Antonino S.), Maselli, D. (Daniele), Nardella, S. (Saverio), Antonio, A. (Antonio), Nicolini, F. (Francesco), Zanobini, M. (Marco), Saccocci, M. (Matteo), Ruggieri, V. G. (Vito G.), Bounader, K. (Karl), Perrotti, A. (Andrea), Rosato, S. (Stefano), D’Errigo, P. (Paola), D’Andrea, V. (Vito), De Feo, M. (Marisa), Tauriainen, T. (Tuomas), Gatti, G. (Giuseppe), and Dalén, M. (Magnus)

Subjects
Antithrombotic, P2Y12, Bleeding, Blood transfusion, Coronary artery bypass grafting, Cardiac surgery
Abstract

Aims: No data exists on inter-institutional differences in terms of adherence to international guidelines regarding the discontinuation of antithrombotics and rates of severe bleeding in coronary artery bypass grafting (CABG). Methods and results: This is an analysis of 7118 patients from the prospective multicentre European CABG (E-CABG) registry who underwent isolated CABG in 15 European centres. Preoperative pause of P2Y12 receptor antagonists shorter than that suggested by the 2017 ESC guidelines (overall 11.6%) ranged from 0.7% to 24.8% between centres (adjusted P

Published
2018

40. Utility of glycated hemoglobin screening in patients undergoing elective coronary artery surgery:prospective, cohort study from the E-CABG registry

Author

Nicolini, F. (Francesco), Santarpino, G. (Giuseppe), Gatti, G. (Giuseppe), Reichart, D. (Daniel), Onorati, F. (Francesco), Faggian, G. (Giuseppe), Dalén, M. (Magnus), Khodabandeh, S. (Sorosh), Fischlein, T. (Theodor), Maselli, D. (Daniele), Nardella, S. (Saverio), Rubino, A. S. (Antonino S.), De Feo, M. (Marisa), Salsano, A. (Antonio), Gherli, R. (Riccardo), Mariscalco, G. (Giovanni), Kinnunen, E.-M. (Eeva-Maija), Ruggieri, V. G. (Vito G.), Bounader, K. (Karl), Saccocci, M. (Matteo), Chocron, S. (Sidney), Airaksinen, J. (Juhani), Perrotti, A. (Andrea), and Biancari, F. (Fausto)

Subjects
HbA1c, diabetes, CABG, coronary artery bypass, glycated hemoglobin
Abstract

Background: Patients with increased glycated hemoglobin (HbA1c) seem to be at increased risk of sternal wound infection (SWI) after coronary artery bypass grafting (CABG). However, it is unclear whether increased baseline HbA1c levels may affect other postoperative outcomes. Material and methods: Data on preoperative levels of HbA1c were collected from 2606 patients undergoing elective isolated CABG from 2015 to 2016 and included in the prospective, multicenter E-CABG registry. Results: The prevalence of HbA1c ≥ 53 mmol/mol (7.0%) among non-diabetics was 5.3%, among non-insulin dependent diabetics was 53.5% and among insulin dependent diabetics was 67.1% (p 75 mmol/mol (9.0%) among non-diabetics was 0.5%, among non-insulin dependent diabetics was 5.8% and among insulin dependent diabetics was 10.6% (p

Published
2018

41. Value of Screening Asymptomatic Carotid Artery Stenosis Prior to Coronary Artery Bypass Grafting: Analysis of the E-CABG Registry

Author

Salsano, A., Santarpino, G., Santini, F., Nicolini, F., De Feo, M., Dalén, M., Fischlein, T., Perrotti, A., Reichart, D., Gatti, G., Onorati, F., Franzese, I., Faggian, G., Bancone, C., Chocron, S., Khodabandeh, S., Rubino, A. S., Maselli, D., Nardella, S., Gherli, R., Zanobini, M., Saccocci, M., Bounader, K., Rosato, S., Tauriainen, T., Mariscalco, G., Airaksinen, J., Ruggieri, V. G., and Biancari, F.

Published
2018

42. Interdisciplinary consensus on indications for transfemoral transcatheter aortic valve implantation (TF-TAVI)

Author

von Scheidt, Wolfgang, primary, Welz, A., additional, Pauschinger, M., additional, Fischlein, T., additional, Schächinger, V., additional, Treede, H., additional, Zahn, R., additional, Hennersdorf, M., additional, Albes, J. M., additional, Bekeredjian, R., additional, Beyer, M., additional, Brachmann, J., additional, Butter, C., additional, Bruch, L., additional, Dörge, H., additional, Eichinger, W., additional, Franke, U. F. W., additional, Friedel, N., additional, Giesler, T., additional, Gradaus, R., additional, Hambrecht, R., additional, Haude, M., additional, Hausmann, H., additional, Heintzen, M. P., additional, Jung, W., additional, Kerber, S., additional, Mudra, H., additional, Nordt, T., additional, Pizzulli, L., additional, Sack, F.-U., additional, Sack, S., additional, Schumacher, B., additional, Schymik, G., additional, Sechtem, U., additional, Stellbrink, C., additional, Stumpf, C., additional, and Hoffmeister, H. M., additional

Published
2019
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48. The rise of new technologies for aortic valve stenosis: A comparison of sutureless and transcatheter aortic valve implantation

Author

D'Onofrio A, Salizzoni S, Rubino AS, Besola L, Filippini C, Colombo A, Agrifoglio M, Fischlein T, Rapetto F, Tarantini G, Dalèn M, Gabbieri D, Meuris B, Savini C, Gatti G, Aiello ML, Biancari F, Livi U, Stefàno PL, Cassese M, Borrello B, Rinaldi M, Mignosa C, Gerosa G, Italian Transcatheter Balloon Expandable Registry, the Sutureless Aortic Valve Implantation Research Groups, ALFIERI , OTTAVIO, D'Onofrio, A, Salizzoni, S, Rubino, A, Besola, L, Filippini, C, Alfieri, Ottavio, Colombo, A, Agrifoglio, M, Fischlein, T, Rapetto, F, Tarantini, G, Dalèn, M, Gabbieri, D, Meuris, B, Savini, C, Gatti, G, Aiello, Ml, Biancari, F, Livi, U, Stefàno, Pl, Cassese, M, Borrello, B, Rinaldi, M, Mignosa, C, Gerosa, G, Italian Transcatheter Balloon Expandable, Registry, and the Sutureless Aortic Valve Implantation Research, Groups

Published
2016

49. Early outcome of bilateral versus single internal mammary artery grafting in the elderly

Author

Rubino, A. S. (Antonino S.), Gatti, G. (Giuseppe), Reichart, D. (Daniel), Tauriainen, T. (Tuomas), De Feo, M. (Marisa), Onorati, F. (Francesco), Pappalardo, A. (Aniello), Chocron, S. (Sidney), Gulbins, H. (Helmut), Dalén, M. (Magnus), Svenarud, P. (Peter), Faggian, G. (Giuseppe), Franzese, I. (Ilaria), Santarpino, G. (Giuseppe), Fischlein, T. (Theodor), Maselli, D. (Daniele), Nardella, S. (Saverio), Gherli, R. (Riccardo), Ahmed, A. (Aamer), Santini, F. (Francesco), Salsano, A. (Antonio), Nicolini, F. (Francesco), Zanobini, M. (Marco), Saccocci, M. (Matteo), Ruggieri, V. G. (Vito G.), Bounader, K. (Karl), Mignosa, C. (Carmelo), D’Errigo, P. (Paola), Rosato, S. (Stefano), Airaksinen, J. (Juhani), Perrotti, A. (Andrea), Biancari, F. (Fausto), Rubino, A. S. (Antonino S.), Gatti, G. (Giuseppe), Reichart, D. (Daniel), Tauriainen, T. (Tuomas), De Feo, M. (Marisa), Onorati, F. (Francesco), Pappalardo, A. (Aniello), Chocron, S. (Sidney), Gulbins, H. (Helmut), Dalén, M. (Magnus), Svenarud, P. (Peter), Faggian, G. (Giuseppe), Franzese, I. (Ilaria), Santarpino, G. (Giuseppe), Fischlein, T. (Theodor), Maselli, D. (Daniele), Nardella, S. (Saverio), Gherli, R. (Riccardo), Ahmed, A. (Aamer), Santini, F. (Francesco), Salsano, A. (Antonio), Nicolini, F. (Francesco), Zanobini, M. (Marco), Saccocci, M. (Matteo), Ruggieri, V. G. (Vito G.), Bounader, K. (Karl), Mignosa, C. (Carmelo), D’Errigo, P. (Paola), Rosato, S. (Stefano), Airaksinen, J. (Juhani), Perrotti, A. (Andrea), and Biancari, F. (Fausto)

Abstract

Background: Bilateral internal mammary artery (BIMA) grafting is increasingly used in elderly patients without evidence of its risks or benefits compared with single internal mammary artery (SIMA) grafting. Methods: In all, 2,899 patients aged 70 years or older (855 [29.5%] underwent BIMA grafting) operated on from January 2015 to December 2016 and included in the prospective multicenter Outcome After Coronary Artery Bypass Grafting (E-CABG) study were considered in this analysis. Results: One-to-one propensity matching resulted in 804 pairs with similar preoperative risk profile. Propensity score matched analysis showed that BIMA grafting was associated with a nonstatistically significant increased risk of inhospital death (2.7% versus 1.6%, p = 0.117). The BIMA grafting cohort had a significantly increased risk of any sternal wound infection (7.7% versus 5.1%, p = 0.031) as well as higher risk of deep sternal wound infection/mediastinitis (4.0% versus 2.2%, p = 0.048). The BIMA grafting cohort required more frequently extracorporeal membrane oxygenation (1.0% versus 0.1%, p = 0.02), and the intensive care unit stay (mean 3.6 versus 2.6 days, p < 0.001) and inhospital stay (mean 11.3 versus 10.0 days, p < 0.001) were significantly longer compared with the SIMA grafting cohort. Test for interaction showed that urgent operation in patients undergoing BIMA grafting was associated with higher risk of inhospital death (5.6% versus 1.3%, p = 0.009). Conclusions: Bilateral internal mammary artery grafting in elderly patients seems to be associated with a worse early outcome compared with SIMA grafting, particularly in patients undergoing urgent operation. Until more conclusive results are gathered, BIMA grafting should be reserved only for elderly patients with stable coronary artery disease, without significant baseline comorbidities and with long life expectancy.

Published
2018

50. Prognostic impact of asymptomatic carotid artery stenosis in patients undergoing coronary artery bypass grafting

Author

Santarpino, G. (Giuseppe), Nicolini, F. (Francesco), De Feo, M. (Marisa), Dalén, M. (Magnus), Fischlein, T. (Theodor), Perrotti, A. (Andrea), Reichart, D. (Daniel), Gatti, G. (Giuseppe), Onorati, F. (Francesco), Franzese, I. (Ilaria), Faggian, G. (Giuseppe), Bancone, C. (Ciro), Chocron, S. (Sidney), Khodabandeh, S. (Sorosh), Rubino, A. S. (Antonino S.), Maselli, D. (Daniele), Nardella, S. (Saverio), Gherli, R. (Riccardo), Salsano, A. (Antonio), Zanobini, M. (Marco), Saccocci, M. (Matteo), Bounader, K. (Karl), Rosato, S. (Stefano), Tauriainen, T. (Tuomas), Mariscalco, G. (Giovanni), Airaksinen, J. (Juhani), Ruggier, V. G. (Vito G.), Biancari, F. (Fausto), Santarpino, G. (Giuseppe), Nicolini, F. (Francesco), De Feo, M. (Marisa), Dalén, M. (Magnus), Fischlein, T. (Theodor), Perrotti, A. (Andrea), Reichart, D. (Daniel), Gatti, G. (Giuseppe), Onorati, F. (Francesco), Franzese, I. (Ilaria), Faggian, G. (Giuseppe), Bancone, C. (Ciro), Chocron, S. (Sidney), Khodabandeh, S. (Sorosh), Rubino, A. S. (Antonino S.), Maselli, D. (Daniele), Nardella, S. (Saverio), Gherli, R. (Riccardo), Salsano, A. (Antonio), Zanobini, M. (Marco), Saccocci, M. (Matteo), Bounader, K. (Karl), Rosato, S. (Stefano), Tauriainen, T. (Tuomas), Mariscalco, G. (Giovanni), Airaksinen, J. (Juhani), Ruggier, V. G. (Vito G.), and Biancari, F. (Fausto)

Abstract

Objectives: The aim of this study was to evaluate the prognostic impact of untreated asymptomatic carotid artery stenosis (CS) in patients undergoing isolated coronary artery bypass grafting (CABG). Methods: This was a post hoc analysis of data from a prospective multicentre observational study. Patients without history of stroke or transient ischaemic attack from the multicentre E-CABG registry who were screened for CS before isolated CABG were included. Results: Among 2813 patients screened by duplex ultrasound and who did not undergo carotid intervention for asymptomatic CS, 11.1% had a stenosis of 50–59%, 6.0% of 60–69%, 3.1% of 70–79%, 1.4% of 80–89%, 0.5% of 90–99%, and 1.1% had carotid occlusion. In the screened population post-operative stroke occurred in 25 patients (0.9%), with an incidence of 1.5% among patients with CS ≥ 50% (n = 649). Pre-operative screening had not found a relevant CS in 15 of 25 patients suffering stroke after CABG. Brain imaging identified cerebral ischaemic injury in 20 patients, which was bilateral in five patients (25%), ipsilateral to a CS ≥ 50% in six (30%), and ipsilateral to a CS ≥ 70% in three (15%). In univariable analysis, the severity of CS was associated with a significantly increased risk of stroke (CS < 50%, 0.7%; 50–59%, 1.0%; 60–69%, 0.6%; 70–79%, 1.2%; 80–89%, 5.1%; 90–99%, 7.7%; occluded, 6.7%, p < .001). In multivariable analysis, a CS of 90–99% (OR 12.03, 95% CI 1.34–108.23) and the presence of an occluded internal carotid artery (OR 8.783, 95% CI 1.820–42.40) were independent predictors of stroke along with urgency of the procedure, severe massive bleeding according to the E-CABG classification, and the presence of a porcelain ascending aorta. Conclusions: Among screened patients with untreated asymptomatic patients, CS ≥ 90% was an independent predictor of post-operative stroke. As this condition has a low prevalence and when left untreated is associated with a relatively low rate of stroke, pre-o

Published
2018

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