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153 results on '"Fiocchi, F."'

1. Sardinia Radio Telescope: General Description, Technical Commissioning and First Light

Author

Bolli, P., Orlati, A., Stringhetti, L., Orfei, A., Righini, S., Ambrosini, R., Bartolini, M., Bortolotti, C., Buffa, F., Buttu, M., Cattani, A., D'Amico, N., Deiana, G., Fara, A., Fiocchi, F., Gaudiomonte, F., Maccaferri, A., Mariotti, S., Marongiu, P., Melis, A., Migoni, C., Morsiani, M., Nanni, M., Nasyr, F., Pellizzoni, A., Pisanu, T., Poloni, M., Poppi, S., Porceddu, I., Prandoni, I., Roda, J., Roma, M., Scalambra, A., Serra, G., Trois, A., Valente, G., Vargiu, G. P., and Zacchiroli, G.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

In the period 2012 June - 2013 October, the Sardinia Radio Telescope (SRT) went through the technical commissioning phase. The characterization involved three first-light receivers, ranging in frequency between 300MHz and 26GHz, connected to a Total Power back-end. It also tested and employed the telescope active surface installed in the main reflector of the antenna. The instrument status and performance proved to be in good agreement with the expectations in terms of surface panels alignment (at present 300 um rms to be improved with microwave holography), gain (~0.6 K/Jy in the given frequency range), pointing accuracy (5 arcsec at 22 GHz) and overall single-dish operational capabilities. Unresolved issues include the commissioning of the receiver centered at 350 MHz, which was compromised by several radio frequency interferences, and a lower-than-expected aperture efficiency for the 22-GHz receiver when pointing at low elevations. Nevertheless, the SRT, at present completing its Astronomical Validation phase, is positively approaching its opening to the scientific community., Comment: 20 pages

Published
2016
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2. Cognitive dysfunction and poor health literacy are common in veterans presenting with acute coronary syndrome: insights from the MEDICATION study

Author

Marzec LN, Carey EP, Lambert-Kerzner AC, Del Giacco EJ, Melnyk SD, Bryson CL, Fahdi IE, Bosworth HB, Fiocchi F, and Ho PM

Subjects
Medicine (General), R5-920
Abstract

Lucas N Marzec,1 Evan P Carey,1 Anne C Lambert-Kerzner,1 Eric J Del Giacco,2 Stephanie D Melnyk,3 Chris L Bryson,4 Ibrahim E Fahdi,2 Hayden B Bosworth,3 Fran Fiocchi,5 P Michael Ho11Division of Cardiology, Denver VA Medical Center, Denver, CO, USA; 2Department of Medicine, Little Rock VA Medical Center, Little Rock, AR, USA; 3Department of Medicine, Durham VA Medical Center, Durham, NC, USA; 4Department of Medicine, Puget Sound VA Medical Center, Seattle, WA, USA; 5American College of Cardiology, Washington, DC, USABackground: Patient nonadherence to cardiac medications following acute coronary syndrome (ACS) is associated with increased risk of recurrent events. However, the prevalence of cognitive dysfunction and poor health literacy among ACS patients and their association with medication nonadherence are poorly understood.Methods: We assessed rates of cognitive dysfunction and poor health literacy among participants of a clinical trial that tested the effectiveness of an intervention to improve medication adherence in patients hospitalized with ACS. Of 254 patients, 249 completed the Rapid Estimate of Adult Literacy in Medicine, Revised (REALM-R) survey, an assessment of risk for poor literacy, and the St Louis University Mental Status (SLUMS) exam, a tool assessing for neurocognitive deficits, during ACS hospitalization. We assessed if SLUMS or REALM-R scores were associated with medication adherence.Results: Based on SLUMS score, 14% of patients were categorized as having dementia, and 52% with mild neurocognitive disorder (MNCD). Based on REALM-R score of ≤6, 34% of patients were categorized as at risk for poor health literacy. There was no association between poor health literacy and medication nonadherence. Of those with MNCD, 35.5% were nonadherent, compared to 17.5% with normal cognitive function and 6.7% with dementia. In multivariable analysis, cognitive dysfunction was associated with medication nonadherence (P=0.007), mainly due to an association between MNCD and nonadherence (odds ratio =12.2, 95% confidence interval =1.9 to 243; P=0.007). Cognitive status was not associated with adherence in patients randomized to the intervention.Conclusion: Cognitive dysfunction and risk for poor health literacy are common in patients hospitalized with ACS. We found an association between MNCD and medication nonadherence in the usual care group but not in the intervention group. These findings suggest efforts to screen for MNCD are needed during ACS hospitalization to identify patients at risk for nonadherence and who may benefit from an adherence intervention.Keyword: medication adherence

Published
2015

3. Stimulus generalization in mice during Pavlovian eyeblink conditioning

Author

Fiocchi, F R, Dijkhuizen, S, Koekkoek, S K E, De Zeeuw, C I, Boele, H J, Fiocchi, F R, Dijkhuizen, S, Koekkoek, S K E, De Zeeuw, C I, and Boele, H J

Abstract

Here we investigate stimulus generalization in a cerebellar learning paradigm, called eyeblink conditioning. Mice were conditioned to close their eyes in response to a 10 kHz tone by repeatedly pairing this tone with an air puff to the eye 250 ms after tone onset. After ten consecutive days of training, when mice showed reliable conditioned eyelid responses to the 10 kHz tone, we started to expose them to tones with other frequencies, ranging from 2 to 20 kHz. We found that mice had a strong generalization gradient, whereby the probability and amplitude of conditioned eyelid responses gradually decreases depending on the dissimilarity with the 10 kHz tone. Tones with frequencies closest to 10kHz evoked the most and largest conditioned eyelid responses and each step away from the 10 kHz tone resulted in fewer and smaller conditioned responses. In addition, we found that tones with lower frequencies resulted in conditioned responses that peaked earlier after tone onset compared to those to tones with higher frequencies. Together, our data show prominent generalization patterns in cerebellar learning. Since the known function of cerebellum is rapidly expanding from pure motor control to domains that include cognition, reward-learning, fear-learning, social function, and even addiction, our data implies generalization controlled by cerebellum in all these domains.Significance StatementConditioned stimuli that resemble each other will evoke a rather similar behavioral response. Here, we investigate this phenomenon of stimulus generalization using Pavlovian eyeblink conditioning to probe cerebellar function. Cerebellum is a brain structure whose known function is rapidly expanding from pure motor control to domains that include cognition, reward-learning, fear-learning, social function, and even addiction. Since we found a strong generalization of the auditory stimulus in eyeblink conditioning, our data implies an important role for generalization in motor and non-moto

Published
2022

4. Stimulus Generalization in Mice during Pavlovian Eyeblink Conditioning

Author

Fiocchi, F. R., Dijkhuizen, S., Koekkoek, S. K.E., De Zeeuw, C. I., Boele, H. J., Fiocchi, F. R., Dijkhuizen, S., Koekkoek, S. K.E., De Zeeuw, C. I., and Boele, H. J.

Abstract

Here, we investigate stimulus generalization in a cerebellar learning paradigm, called eyeblink conditioning. Mice were conditioned to close their eyes in response to a 10-kHz tone by repeatedly pairing this tone with an air puff to the eye 250 ms after tone onset. After 10 consecutive days of training, when mice showed reliable conditioned eyelid responses to the 10-kHz tone, we started to expose them to tones with other frequencies, ranging from 2 to 20 kHz. We found that mice had a strong generalization gradient, whereby the probability and amplitude of conditioned eyelid responses gradually decreases depending on the dissimilarity with the 10-kHz tone. Tones with frequencies closest to 10 kHz evoked the most and largest conditioned eyelid responses and each step away from the 10-kHz tone resulted in fewer and smaller conditioned responses (CRs). In addition, we found that tones with lower frequencies resulted in CRs that peaked earlier after tone onset compared with those to tones with higher frequencies. Together, our data show prominent generalization patterns in cerebellar learning. Since the known function of cerebellum is rapidly expanding from pure motor control to domains that include cognition, reward-learning, fear-learning, social function, and even ad-diction, our data imply generalization controlled by cerebellum in all these domains.

Published
2022

11. Cardiac Magnetic Resonance Characterization of Myocarditis-Like Acute Cardiac Syndrome in COVID-19

Author

Esposito, A., Palmisano, A., Natale, Luigi, Ligabue, G., Peretto, G., Lovato, L., Vignale, D., Fiocchi, F., Marano, Riccardo, Russo, V., Natale L. (ORCID:0000-0002-7949-5119), Marano R. (ORCID:0000-0003-2710-2093), Esposito, A., Palmisano, A., Natale, Luigi, Ligabue, G., Peretto, G., Lovato, L., Vignale, D., Fiocchi, F., Marano, Riccardo, Russo, V., Natale L. (ORCID:0000-0002-7949-5119), and Marano R. (ORCID:0000-0003-2710-2093)

Abstract

Novel coronavirus infection causes a systemic disease (coronavirus disease-2019 [COVID-19]) with, most frequently, respiratory involvement. In addition to systemic and respiratory complications, COVID-19 can reveal itself as a myocarditis-like syndrome (AMCovS), whose underlying mechanism is largely unknown. A limited number of case reports have described cardiac magnetic resonance (CMR) findings in AMCovS; only 2 of which included mapping.

Published
2020

20. Mancanza di correlazione tra segni radiologici di tubercolosi inattiva e risposta immune specifica nei confronti di M. Tuberculosis in pazienti con malattie ematolinfoproliferative

Author

Fantini, R, Losi, M, Ferrari, A, Luppi, F, Spagnolo, P, D'Amico, R, Torricelli, P, Fiocchi, F, Roversi, P, Cerri, S, Rumpianesi, F, Meacci, M, Meccugni, B, Fabbri LM., T, Luppi, M, Richeldi, L, Fantini R, Losi M, Ferrari A, Luppi F, Spagnolo P, D'Amico R, Torricelli P, Fiocchi F, Roversi P, Cerri S, Rumpianesi F, Meacci M, Meccugni B, Fabbri LM. Torelli G, Luppi M, Richeldi L., Fantini, R, Losi, M, Ferrari, A, Luppi, F, Spagnolo, P, D'Amico, R, Torricelli, P, Fiocchi, F, Roversi, P, Cerri, S, Rumpianesi, F, Meacci, M, Meccugni, B, Fabbri LM., T, Luppi, M, Richeldi, L, Fantini R, Losi M, Ferrari A, Luppi F, Spagnolo P, D'Amico R, Torricelli P, Fiocchi F, Roversi P, Cerri S, Rumpianesi F, Meacci M, Meccugni B, Fabbri LM. Torelli G, Luppi M, and Richeldi L.

Published
2010

23. Radiological findings of inactive tuberculosis do not correlate with M. tuberculosis-specific T-cell immunity in high risk patients

Author

Luppi, F, Torricelli, P, Roversi, P, Fiocchi, F, Ferrari, A, Luppi, M, D’Amico, R, Losi, M, Meacci, M, Meccugni, B, Rumpianesi, F, Fabbri, L, Richeldi, L, Luppi F, Torricelli P, Roversi P, Fiocchi F, Ferrari A, Luppi M, D’Amico R, Losi M, Meacci M, Meccugni B, Rumpianesi F, Fabbri L, Richeldi L, Luppi, F, Torricelli, P, Roversi, P, Fiocchi, F, Ferrari, A, Luppi, M, D’Amico, R, Losi, M, Meacci, M, Meccugni, B, Rumpianesi, F, Fabbri, L, Richeldi, L, Luppi F, Torricelli P, Roversi P, Fiocchi F, Ferrari A, Luppi M, D’Amico R, Losi M, Meacci M, Meccugni B, Rumpianesi F, Fabbri L, and Richeldi L

Published
2008

24. Mancanza di correlazione tra segni radiologici di tubercolosi inattiva e risposta immune specifica nei confronti di M. Tuberculosis in pazienti con malattie ematolinfoproliferative

Author

Fantini R, Losi M, Ferrari A, Luppi F, Spagnolo P, D'Amico R, Torricelli P, Fiocchi F, Roversi P, Cerri S, Rumpianesi F, Meacci M, Meccugni B, Fabbri LM. Torelli G, Luppi M, Richeldi L., Fantini, R, Losi, M, Ferrari, A, Luppi, F, Spagnolo, P, D'Amico, R, Torricelli, P, Fiocchi, F, Roversi, P, Cerri, S, Rumpianesi, F, Meacci, M, Meccugni, B, Fabbri LM., T, Luppi, M, and Richeldi, L

Subjects
Malattie ematolinfoproliferative, Tuberculosis, IFN-gamma based tests
Published
2010

25. Radiological findings of inactive tuberculosis do not correlate with M. tuberculosis-specific T-cell immunity in high risk patients

Author

Luppi F, Torricelli P, Roversi P, Fiocchi F, Ferrari A, Luppi M, D’Amico R, Losi M, Meacci M, Meccugni B, Rumpianesi F, Fabbri L, Richeldi L, Luppi, F, Torricelli, P, Roversi, P, Fiocchi, F, Ferrari, A, Luppi, M, D’Amico, R, Losi, M, Meacci, M, Meccugni, B, Rumpianesi, F, Fabbri, L, and Richeldi, L

Subjects
TB Infection. IFN-gamma-based test
Published
2008

26. Status of the radio receiver system of the Sardina Radio Telescope

Author

Valente, G., additional, Orfei, A., additional, Nesti, R., additional, Navarrini, A., additional, Mariotti, S., additional, Bolli, P., additional, Pisanu, T., additional, Roda, J., additional, Cresci, L., additional, Marongiu, P., additional, Scalambra, A., additional, Panella, D., additional, Ladu, A., additional, Cattani, A., additional, Carbonaro, L., additional, Urru, E., additional, Cremonini, A., additional, Fiocchi, F., additional, Maccaferri, A., additional, Morsiani, M., additional, and Poloni, M., additional

Published
2016
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30. Sardinia Radio Telescope: General Description, Technical Commissioning and First Light

Author

Bolli, P., primary, Orlati, A., additional, Stringhetti, L., additional, Orfei, A., additional, Righini, S., additional, Ambrosini, R., additional, Bartolini, M., additional, Bortolotti, C., additional, Buffa, F., additional, Buttu, M., additional, Cattani, A., additional, D'Amico, N., additional, Deiana, G., additional, Fara, A., additional, Fiocchi, F., additional, Gaudiomonte, F., additional, Maccaferri, A., additional, Mariotti, S., additional, Marongiu, P., additional, Melis, A., additional, Migoni, C., additional, Morsiani, M., additional, Nanni, M., additional, Nasyr, F., additional, Pellizzoni, A., additional, Pisanu, T., additional, Poloni, M., additional, Poppi, S., additional, Porceddu, I., additional, Prandoni, I., additional, Roda, J., additional, Roma, M., additional, Scalambra, A., additional, Serra, G., additional, Trois, A., additional, Valente, G., additional, Vargiu, G. P., additional, and Zacchiroli, G., additional

Published
2015
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31. Le bois dans les tombes de Souvigny

Author

Blondel, François, Fiocchi, F., Archéologie, Terre, Histoire, Sociétés [Dijon] (ARTeHiS), Centre National de la Recherche Scientifique (CNRS)-Université de Bourgogne (UB)-Ministère de la Culture et de la Communication (MCC), Archéologie, Terre, Histoire, Sociétés [Dijon] ( ARTeHiS ), Ministère de la Culture et de la Communication ( MCC ) -Université de Bourgogne ( UB ) -Centre National de la Recherche Scientifique ( CNRS ), and Desbois-Garcia, Sophie

Subjects
[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and Prehistory, Archéologie, [SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory, [ SHS.ARCHEO ] Humanities and Social Sciences/Archaeology and Prehistory
Published
2010

43. Commissioning of the Sardinia Radio Telescope in Italy: Results and perspectives

Author

Ambrosini, Roberto, primary, Ambrosini, R., additional, Bocchinu, A., additional, Bolli, P., additional, Buffa, F., additional, Buttu, M., additional, Cattani, A., additional, D'Amico, N., additional, Deiana, G.L., additional, Fara, A., additional, Fiocchi, F., additional, Gaudiomonte, F., additional, Maccaferri, A., additional, Mariotti, S., additional, Marongiu, P., additional, Melis, A., additional, Melis, G., additional, Migoni, C., additional, Morsiani, M., additional, Nanni, M., additional, Nasyr, F., additional, Nesti, R., additional, Orfei, A., additional, Orlati, A., additional, Perini, F., additional, Pernechele, C., additional, Pilloni, S., additional, Pisanu, T., additional, Poloni, M., additional, Poppi, S., additional, Porceddu, I., additional, Righini, S., additional, Roda, J., additional, Scalambra, A., additional, Schirru, M. R., additional, Serra, G., additional, Stringhetti, L., additional, Trois, A., additional, Tuveri, A., additional, Valente, G., additional, Vargiu, G., additional, and Zacchiroli, G., additional

Published
2014
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45. The sardinia radio telescope: Overview and status

Author

Ambrosini, R., primary, Bocchinu, A., additional, Bolli, P., additional, Buffa, F., additional, Buttu, M., additional, Cattani, A., additional, D'Amico, N., additional, Deiana, G. L., additional, Fara, A., additional, Fiocchi, F., additional, Gaudiomonte, F., additional, Maccaferri, A., additional, Mariotti, S., additional, Marongiu, P., additional, Melis, A., additional, Melis, G., additional, Migoni, C., additional, Morsiani, M., additional, Nanni, M., additional, Nasyr, F., additional, Nesti, R., additional, Orfei, A., additional, Orlati, A., additional, Perini, F., additional, Pernechele, C., additional, Pilloni, S., additional, Pisanu, T., additional, Poloni, M., additional, Poppi, S., additional, Porceddu, I., additional, Righini, S., additional, Roda, J., additional, Scalambra, A., additional, Schirru, M. R., additional, Serra, G., additional, Stringhetti, L., additional, Trois, A., additional, Tuveri, A., additional, Valente, G., additional, Vargiu, G., additional, and Zacchiroli, G., additional

Published
2013
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47. Diving into the Sardinia Radio Telescope minor servo system

Author

Buttu, M., primary, Orlati, A., additional, Zacchiroli, G., additional, Morsiani, M., additional, Fiocchi, F., additional, Buffa, F., additional, Maccaferri, G., additional, Vargiu, G. P., additional, Migoni, C., additional, Poppi, S., additional, Righini, S., additional, and Melis, A., additional

Published
2012
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50. Activated platelets are the source of elevated levels of soluble CD40 ligand in the circulation of inflammatory bowel disease patients.

Author

Danese, Silvio, Katz, Ja, Saibeni, S, Papa, Alfredo, Gasbarrini, Antonio, Vecchi, M, Fiocchi, F., Papa, Alfredo (ORCID:0000-0002-4186-7298), Gasbarrini, Antonio (ORCID:0000-0002-7278-4823), Danese, Silvio, Katz, Ja, Saibeni, S, Papa, Alfredo, Gasbarrini, Antonio, Vecchi, M, Fiocchi, F., Papa, Alfredo (ORCID:0000-0002-4186-7298), and Gasbarrini, Antonio (ORCID:0000-0002-7278-4823)

Abstract

BACKGROUND: The CD40/CD40L system, a key regulator and amplifier of immune reactivity, is activated in inflammatory bowel disease (IBD) mucosa. AIMS: To determine whether plasma levels of sCD40L are elevated in Crohn's disease (CD) and ulcerative colitis (UC) patients compared with normal controls, to investigate the cellular source of sCD40L, and to explore CD40L induction mechanisms. PATIENTS: CD, UC, and normal control subjects were studied. METHODS: The concentration of sCD40L in plasma and supernatants of freshly isolated platelets and autologous peripheral blood T cells (PBT) was measured by ELISA. Surface CD40L expression level was measured by flow cytometry in resting and thrombin activated platelets, and unstimulated and CD3/CD28 stimulated PBT before and after coculture with human intestinal microvascular endothelial cells (HIMEC). RESULTS: Compared with normal controls, plasma sCD40L levels were significantly higher in both CD and UC patients and proportional to the extent of mucosal inflammation. Platelets from IBD patients displayed a significantly higher surface CD40L expression than those from control subjects, and released greater amounts of sCD40L than autologous PBT. Contact with IL-1beta activated HIMEC induced significant upregulation of CD40L surface expression and release by platelets. CONCLUSIONS: Elevated levels of sCD40L in the circulation of IBD patients reflect enhanced surface expression and release of CD40L by platelets. This phenomenon translates to an increased platelet activation state apparently induced by passage through an inflamed mucosal microvascular bed, a conclusion supported by the positive correlation of plasma sCD40L levels with the extent of anatomical involvement by IBD. These results suggest that platelet-endothelial interactions critically contribute to activation of the CD40 pathway in IBD.

Published
2003

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