Search

Your search keyword '"Finlay, Jonathan L"' showing total 884 results
Start Over Author "Finlay, Jonathan L"
884 results on '"Finlay, Jonathan L"'

2. Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis

Author

Light, Nicholas, Layeghifard, Mehdi, Attery, Ayush, Subasri, Vallijah, Zatzman, Matthew, Anderson, Nathaniel D., Hatkar, Rupal, Blay, Sasha, Chen, David, Novokmet, Ana, Fuligni, Fabio, Tran, James, de Borja, Richard, Agarwal, Himanshi, Waldman, Larissa, Abegglen, Lisa M., Albertson, Daniel, Finlay, Jonathan L., Hansford, Jordan R., Behjati, Sam, Villani, Anita, Gerstung, Moritz, Alexandrov, Ludmil B., Somers, Gino R., Schiffman, Joshua D., Rotter, Varda, Malkin, David, and Shlien, Adam

Published
2023
Full Text
View/download PDF

3. Marrow-ablative consolidation chemotherapy (HDCT) to decrease the development of choroid plexus carcinoma (CPC) specific relapse in high-risk TP53-mutated (germline or somatic) young children with newly diagnosed CPC.

Author

Osorio, Diana S., primary, Yankelevich, Maxim, additional, Zaky, Wafik Tharwat, additional, Lafay-Cousin, Lucie, additional, Margol, Ashley S., additional, Toll, Stephanie, additional, Quiroz, Lina, additional, Fox, Javier E., additional, Hanson, Derek, additional, Gardner, Sharon L., additional, Prados, Michael, additional, Mueller, Sabine, additional, and Finlay, Jonathan L., additional

Published
2024
Full Text
View/download PDF

5. Molecular characterization of gliomas and glioneuronal tumors amid Noonan syndrome: cancer predisposition examined.

Author

Shatara, Margaret, Schieffer, Kathleen M., Melas, Marilena, Varga, Elizabeth A., Thomas, Diana, Bucknor, Brianna A., Costello, Heather M., Wheeler, Gregory, Kelly, Benjamin J., Miller, Katherine E., Rodriguez, Diana P., Mathew, Mariam T., Lee, Kristy, Crotty, Erin, Leary, Sarah, Paulson, Vera A., Cole, Bonnie, Abdelbaki, Mohamed S., Finlay, Jonathan L., and Lazow, Margot A.

Subjects
NOONAN syndrome, TUMOR classification, YOUNG adults, DNA analysis, NUCLEOTIDE sequencing
Abstract

Introduction: In the setting of pediatric and adolescent young adult cancer, increased access to genomic profiling has enhanced the detection of genetic variation associated with cancer predisposition, including germline syndromic conditions. Noonan syndrome (NS) is associated with the germline RAS pathway activating alterations and increased risk of cancer. Herein, we describe our comprehensive molecular profiling approach, the association of NS with glioma and glioneuronal tumors, and the clinical and histopathologic characteristics associated with the disease. Methods: Within an institutional pediatric cancer cohort (n = 314), molecular profiling comprised of paired somatic disease-germline comparator exome analysis, RNA sequencing, and tumor classification by DNA methylation analysis was performed. Results: Through the implementation of paired analysis, this study identified 4 of 314 (1.3%) individuals who harbored a germline PTPN11 variant associated with NS, of which 3 individuals were diagnosed with a glioma or glioneuronal tumor. Furthermore, we extend this study through collaboration with a peer institution to identify two additional individuals with NS and a glioma or glioneuronal tumor. Notably, in three of five (60%) individuals, paired genomic profiling led to a previously unrecognized diagnosis of Noonan syndrome despite an average age of cancer diagnosis of 16.8 years. The study of the disease-involved tissue identified signaling pathway dysregulation through somatic alteration of genes involved in cellular proliferation, survival, and differentiation. Discussion: Comparative pathologic findings are presented to enable an indepth examination of disease characteristics. This comprehensive analysis highlights the association of gliomas and glioneuronal tumors with RASopathies and the potential therapeutic challenges and importantly demonstrates the utility of genomic profiling for the identification of germline cancer predisposition. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

6. Intracranial non-germinomatous germ cell tumors in children and adolescents: how can the experience from an uppermiddle-income country contribute to the worldwide effort to improve outcomes?

Author

Cappellano, Andrea M., primary, Dassi, Natalia, additional, Mançano, Bruna M., additional, Epelman, Sidnei, additional, Almeida, Daniela B., additional, Cavalheiro, Sergio, additional, Dastoli, Patricia A., additional, Alves, Maria T. S., additional, Nicacio, Jardel M., additional, Costa, Marcos D. S., additional, Silva, Frederico A., additional, Aguiar, Simone S., additional, Figueiredo, Maria L., additional, Chen, Michael, additional, Silva, Nasjla S., additional, and Finlay, Jonathan L., additional

Published
2024
Full Text
View/download PDF

8. Diffusion Tensor Imaging and Neurobehavioral Outcome in Children With Brain Tumors Treated With Chemotherapy

Author

Nelson, Mary Baron, Compton, Peggy, Macey, Paul M, Patel, Sunita K, Jacob, Eufemia, O’Neil, Sharon, Ogren, Jennifer, Finlay, Jonathan L, and Harper, Ronald M

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Rare Diseases, Clinical Research, Brain Cancer, Behavioral and Social Science, Pediatric, Basic Behavioral and Social Science, Stem Cell Research - Nonembryonic - Human, Neurosciences, Brain Disorders, Stem Cell Research, Childhood Injury, Mental Health, Cancer, Physical Injury - Accidents and Adverse Effects, Biomedical Imaging, Anisotropy, Antineoplastic Agents, Brain, Brain Neoplasms, Case-Control Studies, Child, Child, Preschool, Cognition Disorders, Diffusion Tensor Imaging, Female, Hematopoietic Stem Cell Transplantation, Humans, Male, Neuropsychological Tests, Quality of Life, Survivors, adverse effects, central nervous system tumors, chemotherapy, cognitive functioning
Abstract

BackgroundChildhood brain tumor survivors (CBTS) often experience treatment-related neurocognitive deficits affecting quality of life (QOL), but systemic chemotherapy contributions to outcomes are unclear. Our objective was to relate brain tissue changes to neurocognitive and QOL effects after systemic myeloablative chemotherapy with autologous hematopoietic progenitor cell rescue in CBTS.ProcedureRegional brain volumes and diffusion tensor indices were correlated with neurocognitive, behavioral, and QOL measures, and compared between 8 CBTS (mean age 8.5 years, mean age at diagnosis 32 months), and 9 healthy controls (mean 9.3 years).ResultsOverall QOL, school, and psychosocial functioning were significantly lower in patients (P < .05). Most patients scored within normative ranges on neurocognitive and behavioral assessment. Elevated mean diffusivity and decreased fractional anisotropy, indicating gray and white matter injury, respectively, appeared in memory and executive functioning areas. Low scores on Inhibition on the Neuropsychological Assessment-II were correlated with elevated mean diffusivity in prefrontal cortex.ConclusionsBrain injury, decreased QOL, and to a lesser extent, executive functioning deficits appear in CBTS treated with myeloablative chemotherapy and autologous hematopoietic progenitor cell rescue. Early cognitive and psychological assessment and intervention are warranted in this population.

Published
2016

9. Discovery of clinically relevant fusions in pediatric cancer

Author

LaHaye, Stephanie, Fitch, James R., Voytovich, Kyle J., Herman, Adam C., Kelly, Benjamin J., Lammi, Grant E., Arbesfeld, Jeremy A., Wijeratne, Saranga, Franklin, Samuel J., Schieffer, Kathleen M., Bir, Natalie, McGrath, Sean D., Miller, Anthony R., Wetzel, Amy, Miller, Katherine E., Bedrosian, Tracy A., Leraas, Kristen, Varga, Elizabeth A., Lee, Kristy, Gupta, Ajay, Setty, Bhuvana, Boué, Daniel R., Leonard, Jeffrey R., Finlay, Jonathan L., Abdelbaki, Mohamed S., Osorio, Diana S., Koo, Selene C., Koboldt, Daniel C., Wagner, Alex H., Eisfeld, Ann-Kathrin, Mrózek, Krzysztof, Magrini, Vincent, Cottrell, Catherine E., Mardis, Elaine R., Wilson, Richard K., and White, Peter

Published
2021
Full Text
View/download PDF

10. Clinically aggressive pediatric spinal ependymoma with novel MYC amplification demonstrates molecular and histopathologic similarity to newly described MYCN-amplified spinal ependymomas

Author

Shatara, Margaret, Schieffer, Kathleen M., Klawinski, Darren, Thomas, Diana L., Pierson, Christopher R., Sribnick, Eric A., Jones, Jeremy, Rodriguez, Diana P., Deeg, Carol, Hamelberg, Elizabeth, LaHaye, Stephanie, Miller, Katherine E., Fitch, James, Kelly, Benjamin, Leraas, Kristen, Pfau, Ruthann, White, Peter, Magrini, Vincent, Wilson, Richard K., Mardis, Elaine R., Abdelbaki, Mohamed S., Finlay, Jonathan L., Boué, Daniel R., Cottrell, Catherine E., Ghasemi, David R., Pajtler, Kristian W., and Osorio, Diana S.

Published
2021
Full Text
View/download PDF

12. Molecular classification of a complex structural rearrangement of the RB1 locus in an infant with sporadic, isolated, intracranial, sellar region retinoblastoma

Author

Schieffer, Kathleen M., Feldman, Alexander Z., Kautto, Esko A., McGrath, Sean, Miller, Anthony R., Hernandez-Gonzalez, Maria Elena, LaHaye, Stephanie, Miller, Katherine E., Koboldt, Daniel C., Brennan, Patrick, Kelly, Benjamin, Wetzel, Amy, Agarwal, Vibhuti, Shatara, Margaret, Conley, Suzanne, Rodriguez, Diana P., Abu-Arja, Rolla, Shaikhkhalil, Ala, Snuderl, Matija, Orr, Brent A., Finlay, Jonathan L., Osorio, Diana S., Drapeau, Annie I., Leonard, Jeffrey R., Pierson, Christopher R., White, Peter, Magrini, Vincent, Mardis, Elaine R., Wilson, Richard K., Cottrell, Catherine E., and Boué, Daniel R.

Published
2021
Full Text
View/download PDF

13. Impact of tumor location and pathological discordance on survival of children with midline high-grade gliomas treated on Children’s Cancer Group high-grade glioma study CCG-945

Author

Eisenstat, David D, Pollack, Ian F, Demers, Alain, Sapp, Mark V, Lambert, Pascal, Weisfeld-Adams, James D, Burger, Peter C, Gilles, Floyd, Davis, Richard L, Packer, Roger, Boyett, James M, and Finlay, Jonathan L

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Rare Diseases, Brain Cancer, Neurosciences, Cancer, Brain Disorders, Adolescent, Brain Neoplasms, Child, Child, Preschool, Combined Modality Therapy, Disease-Free Survival, Female, Glioma, Humans, Infant, Infant, Newborn, Kaplan-Meier Estimate, Male, Neoplasm Grading, Prognosis, Childhood malignant gliomas, Anaplastic astrocytoma, Glioblastoma multiforme, Chemotherapy, Midline tumors, Thalamus, Hypothalamus, Basal ganglia, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract

Children with high-grade glioma (HGG) have a poor prognosis compared to those with low-grade glioma (LGG). Adjuvant chemotherapy may be beneficial, but its optimal use remains undetermined. Histology and extent of resection are important prognostic factors. We tested the hypothesis that patients with midline HGG treated on Children's Cancer Group Study (CCG) CCG-945 have a worse prognosis compared to the entire group. Of 172 children eligible for analysis, 60 had midline tumors primarily localized to the thalamus, hypothalamus and basal ganglia. Time-to-progression and death were determined from the date of initial diagnosis, and survival curves were calculated. Univariate analyses were undertaken for extent of resection, chemotherapy regimen, anatomic location, histology, proliferation index, MGMT status and p53 over-expression. For the entire midline tumor group, 5-year PFS and OS were 18.3 ± 4.8 and 25 ± 5.4 %, respectively. Many patients only had a biopsy (43.3 %). The sub-groups with near/total resection and hypothalamic location appeared to have better PFS and OS. However, the effect of tumor histology on OS was significant for children with discordant diagnoses on central pathology review of LGG compared to HGG. Proliferative index (MIB-1 > 36 %), MGMT and p53 over-expression correlated with poor outcomes. Children treated on CCG-945 with midline HGG have a worse prognosis when compared to the entire group. The midline location may directly influence the extent of resection. Central pathology review and entry of patients on clinical trials continue to be priorities to improve outcomes for children with HGG.

Published
2015

15. Structural brain alterations in children an average of 5 years after surgery and chemotherapy for brain tumors

Author

Nelson, Mary Baron, Macey, Paul M, Harper, Ronald M, Jacob, Eufemia, Patel, Sunita K, Finlay, Jonathan L, Nelson, Marvin D, and Compton, Peggy

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Neurosciences, Brain Cancer, Childhood Injury, Brain Disorders, Pediatric, Cancer, Biomedical Imaging, Clinical Research, Physical Injury - Accidents and Adverse Effects, Rare Diseases, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Neurological, Adolescent, Anisotropy, Brain, Brain Neoplasms, Child, Child, Preschool, Cross-Sectional Studies, Diffusion Tensor Imaging, Female, Gray Matter, Humans, Magnetic Resonance Imaging, Male, White Matter, Mean diffusivity, Diffusion tensor imaging, Pediatrics, Medulloblastoma, Oncology and Carcinogenesis, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract

Young children with brain tumors are often treated with high-dose chemotherapy after surgery to avoid brain tissue injury associated with irradiation. The effects of systemic chemotherapy on healthy brain tissue in this population, however, are unclear. Our objective was to compare gray and white matter integrity using MRI procedures in children with brain tumors (n = 7, mean age 8.3 years), treated with surgery and high-dose chemotherapy followed by autologous hematopoietic cell rescue (AuHCR) an average of 5.4 years earlier, to age- and gender-matched healthy controls (n = 9, mean age 9.3 years). Diffusion tensor imaging data were collected to evaluate tissue integrity throughout the brain, as measured by mean diffusivity (MD), a marker of glial, neuronal, and axonal status, and fractional anisotropy (FA), an index of axonal health. Individual MD and FA maps were calculated, normalized, smoothed, and compared between groups using analysis of covariance, with age and sex as covariates. Higher MD values, indicative of injury, emerged in patients compared with controls (p < .05, corrected for multiple comparisons), and were especially apparent in the central thalamus, external capsule, putamen, globus pallidus and pons. Reduced FA values in some regions did not reach significance after correction for multiple comparisons. Children treated with surgery and high-dose chemotherapy with AuHCR for brain tumors an average of 5.4 years earlier show alterations in white and gray matter in multiple brain areas distant from the tumor site, raising the possibility for long-term consequences of the tumor or treatment.

Published
2014

16. Final report of the phase II NEXT/CNS-GCT-4 trial: GemPOx followed by marrow-ablative chemotherapy for recurrent intracranial germ cell tumors.

Author

Shatara, Margaret, Blue, Megan, Stanek, Joseph, Liu, Yin A, Prevedello, Daniel M, Giglio, Pierre, Puduvalli, Vinay K, Gardner, Sharon L, Allen, Jeffrey C, Wong, Kenneth K, Nelson, Marvin D, Gilles, Floyd H, Adams, Roberta H, Pauly, Jasmine, O'Halloran, Katrina, Margol, Ashley S, Dhall, Girish, and Finlay, Jonathan L

Subjects
GERM cell tumors, ADVERSE health care events, CANCER chemotherapy, TUMOR markers, PROGENITOR cells, DISEASE progression, GERMINOMA
Abstract

Background Patients with relapsed intracranial germinoma can achieve durable remission with standard chemotherapy regimens and/or reirradiation; however, innovative therapies are required for patients with relapsed and/or refractory intracranial nongerminomatous germ cell tumors (NGGCTs) due to their poor prognosis. Improved outcomes have been reported using reinduction chemotherapy to achieve minimal residual disease, followed by marrow-ablative chemotherapy (HDCx) with autologous hematopoietic progenitor cell rescue (AuHPCR). We conducted a phase II trial evaluating the response and toxicity of a 3-drug combination developed for recurrent intracranial germ cell tumors consisting of gemcitabine, paclitaxel, and oxaliplatin (GemPOx). Methods A total of 9 patients with confirmed relapsed or refractory intracranial GCT were enrolled after signing informed consent, and received at least 2 cycles of GemPOx, of which all but 1 had relapsed or refractory NGGCTs. One patient with progressive disease was found to have pathologically confirmed malignant transformation to pure embryonal rhabdomyosarcoma (without GCT elements), hence was ineligible and not included in the analysis. Patients who experienced sufficient responses proceeded to receive HDCx with AuHPCR. Treatment response was determined based on radiographic tumor assessments and tumor markers. Results A total of 7 patients achieved sufficient response and proceeded with HDCx and AuHPCR, and 5 subsequently received additional radiotherapy. A total of 2 patients developed progressive disease while receiving GemPOx. Myelosuppression and transaminitis were the most common treatment-related adverse events. With a mean follow-up of 44 months, 4 patients (3 NGGCTs, 1 germinoma) are alive without evidence of disease. Conclusions GemPOx demonstrates efficacy in facilitating stem cell mobilization, thus facilitating the feasibility of both HDCx and radiotherapy. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

17. Final Report of the Phase II NEXT/CNS-GCT-4 Trial: GemPOx followed by Marrow-ablative Chemotherapy for Recurrent Intracranial Germ Cell Tumors

Author

Shatara, Margaret, primary, Blue, Megan, additional, Stanek, Joseph, additional, Liu, Yin A, additional, Prevedello, Daniel M, additional, Giglio, Pierre, additional, Puduvalli, Vinay K, additional, Gardner, Sharon L, additional, Allen, Jeffrey C, additional, Wong, Kenneth K, additional, Nelson, Marvin D, additional, Gilles, Floyd H, additional, Adams, Roberta H, additional, Pauly, Jasmine, additional, O’Halloran, Katrina, additional, Margol, Ashley S, additional, Dhall, Girish, additional, and Finlay, Jonathan L, additional

Published
2023
Full Text
View/download PDF

20. YAP1-FAM118B Fusion Defines a Rare Subset of Childhood and Young Adulthood Meningiomas

Author

Schieffer, Kathleen M., Agarwal, Vibhuti, LaHaye, Stephanie, Miller, Katherine E., Koboldt, Daniel C., Lichtenberg, Tara, Leraas, Kristen, Brennan, Patrick, Kelly, Benjamin J., Crist, Erin, Rusin, Jerome, Finlay, Jonathan L., Osorio, Diana S., Sribnick, Eric A., Leonard, Jeffrey R., Feldman, Alexander, Orr, Brent A., Serrano, Jonathan, Vasudevaraja, Varshini, Snuderl, Matija, White, Peter, Magrini, Vincent, Wilson, Richard K., Mardis, Elaine R., Boué, Daniel R., and Cottrell, Catherine E.

Published
2020
Full Text
View/download PDF

23. Pre-irradiation intensive induction and marrow-ablative consolidation chemotherapy in young children with newly diagnosed high-grade brainstem gliomas: report of the “head-start” I and II clinical trials

Author

Osorio, Diana S., Patel, Neha, Ji, Lingyun, Sposto, Richard, Stanek, Joseph, Gardner, Sharon L., Allen, Jeffrey C., Cornelius, Albert, McCowage, Geoffrey B., Termuhlen, Amanda, Dunkel, Ira J., Comito, Melanie, Garvin, James, and Finlay, Jonathan L.

Published
2018
Full Text
View/download PDF

25. Characterizing temporal genomic heterogeneity in pediatric low-grade gliomas

Author

Lazow, Margot A., Hoffman, Lindsey, Schafer, Austin, Osorio, Diana S., Boué, Daniel R., Rush, Sarah, Wright, Erin, Lane, Adam, DeWire-Schottmiller, Mariko D., Smolarek, Teresa, Sipple, Jared, Taggert, Heather, Reuss, Jaime, Salloum, Ralph, Hummel, Trent R., de Blank, Peter, Pillay-Smiley, Natasha, Sutton, Mary E., Asher, Anthony, Stevenson, Charles B., Drissi, Rachid, Finlay, Jonathan L., Fouladi, Maryam, and Fuller, Christine

Published
2020
Full Text
View/download PDF

26. Evaluation of the Pediatric Neuro-Oncology Resources Available in Chile

Author

Abu-Arja, Mohammad H., Rojas del Río, Nicolás, Morales La Madrid, Andres, Lassaletta, Alvaro, Coven, Scott L., Moreno, Rosa, Valero, Miguel, Perez, Veronica, Espinoza, Felipe, Fernandez, Eduardo, Santander, José, Tordecilla, Juan, Oyarce, Veronica, Kopp, Katherine, Bartels, Ute, Qaddoumi, Ibrahim, Finlay, Jonathan L., Cáceres, Adrián, Reyes, Adrián, Espinoza, Ximena, and Osorio, Diana S.

Published
2021
Full Text
View/download PDF

27. Supplementary Data S3 from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
Full Text
View/download PDF

28. FIGURE 2 from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
Full Text
View/download PDF

29. FIGURE 3 from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
Full Text
View/download PDF

30. TABLE 1 from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
Full Text
View/download PDF

31. TABLE 2 from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
Full Text
View/download PDF

32. FIGURE 1 from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
Full Text
View/download PDF

33. FIGURE 5 from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
Full Text
View/download PDF

34. FIGURE 4 from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
Full Text
View/download PDF

35. Supplementary Figures S1-S12 from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
Full Text
View/download PDF

36. Data from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
Full Text
View/download PDF

38. Contributors

Author

Abu-Gheida, Ibrahim, primary, Allen, Deborah Hutchinson, additional, Anderson, John, additional, Aquino, Anthony, additional, Bayik, Defne, additional, Bourekas, Eric C., additional, Braun, Sarah Ellen, additional, Buckner, Jan C., additional, Byer, Lennox, additional, Cachia, David, additional, Carpenter, Candice, additional, Chamberlain, Marc C., additional, Chao, Samuel T., additional, Chukwueke, Ugonma N., additional, Coven, Scott L., additional, Donovan, Laura E., additional, Elder, J. Bradley, additional, Ferguson, Sherise D., additional, Field, Melvin, additional, Finlay, Jonathan L., additional, Goumnerova, Liliana C., additional, Guha-Thakurta, Nandita, additional, Gupta, Shabarni, additional, Gwyn, P. Gage, additional, Halasz, Lia M., additional, Heimberger, Amy B., additional, Henson, John W., additional, Kardan, Arash, additional, Kline-Nunnally, Cassie, additional, Kreth, Friedrich-Wilhelm, additional, Lach, Michael A., additional, Lassman, Andrew B., additional, Lathia, Justin D., additional, Lee, Christine K., additional, Lo, Simon S., additional, Loughan, Ashlee R., additional, Mamoun, Ihsan, additional, Makar, Sherif M., additional, Mandel, Jacob J., additional, Marcus, Karen J., additional, Marta, Gustavo Nader, additional, Maschio, Marta, additional, Mehta, Minesh P., additional, Miller, Julie J., additional, Mohyeldin, Ahmed, additional, Moraes, Fabio Y., additional, Mueller, Sabine, additional, Murphy, Erin S., additional, Newman, William C., additional, Newton, Herbert B., additional, Paladin, Francesco, additional, Paleologos, Nina A., additional, Patel, Akash J., additional, Petras, Katarina, additional, Pham, Lily C., additional, Phillips, Kester A., additional, Poelstra, Raymond, additional, Prayson, R.A., additional, Reardon, David, additional, Reed, Marilyn, additional, Richards, Tyler, additional, Richard, Hope T., additional, Ruff, Michael W., additional, Sachdev, Sean, additional, Satter, Martin, additional, Schiff, David, additional, Sejpal, Samir, additional, Sittenfeld, Sarah, additional, Slone, H. Wayne, additional, Srivastava, Sanjeeva, additional, Straehla, Joelle P., additional, Suh, John H., additional, Taillibert, Sophie, additional, Thon, Niklas, additional, Tihan, Tarik, additional, Tonn, Joerg-Christian, additional, Volovetz, Josephine, additional, Wang, Joshua L., additional, Weathers, Shiao-Pei, additional, Wen, Patrick Y., additional, Williams, Vonetta M., additional, and Yamamoto, E., additional

Published
2019
Full Text
View/download PDF

39. Neurologic Emergencies

Author

Sabnis, Amit, Finlay, Jonathan L., Mueller, Sabine, Feusner, James H., editor, Hastings, Caroline A., editor, and Agrawal, Anurag K., editor

Published
2015
Full Text
View/download PDF

42. Multiple germline events contribute to cancer development in patients with Li-Fraumeni syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, additional, Kanwar, Nisha, additional, Brzezinski, Jack, additional, Luo, Ping, additional, Hansford, Jordan R, additional, Cairney, Elizabeth, additional, Portwine, Carol, additional, Elser, Christine, additional, Finlay, Jonathan L., additional, Nichols, Kim E., additional, Alon, Noa, additional, Brunga, Ledia, additional, Anson, Jo, additional, Kohlmann, Wendy, additional, de Andrade, Kelvin C., additional, Khincha, Payal P., additional, Savage, Sharon A., additional, Schiffman, Joshua D, additional, Weksberg, Rosanna, additional, Pugh, Trevor J., additional, Villani, Anita, additional, Shlien, Adam, additional, Goldenberg, Anna, additional, and Malkin, David, additional

Published
2023
Full Text
View/download PDF

43. Outcome of Children and Adolescents With Primary Intracranial Germinoma Treated With Chemotherapy and Reduced Dose-Field Irradiation: A Prospective Brazilian Experience

Author

Cappellano, Andrea Maria, primary, Dassi, Natalia, additional, Mançano, Bruna, additional, Epelman, Sidnei, additional, Almeida, Daniela B., additional, Cavalheiro, Sergio, additional, Dastoli, Patricia A., additional, Seixas, Maria Teresa, additional, Nicacio, Jardel M., additional, Costa, Marcos D., additional, Silva, Frederico A., additional, Aguiar, Simone S., additional, Almeida, Carlos R., additional, Teixeira, Gustavo R., additional, Chen, Michael, additional, Figueiredo, Maria Luisa, additional, Silva, Nasjla S., additional, and Finlay, Jonathan L., additional

Published
2023
Full Text
View/download PDF

44. Figure S4 from Molecular Characterization of Choroid Plexus Tumors Reveals Novel Clinically Relevant Subgroups

Author

Merino, Diana M., primary, Shlien, Adam, primary, Villani, Anita, primary, Pienkowska, Malgorzata, primary, Mack, Stephen, primary, Ramaswamy, Vijay, primary, Shih, David, primary, Tatevossian, Ruth, primary, Novokmet, Ana, primary, Choufani, Sanaa, primary, Dvir, Rina, primary, Ben-Arush, Myran, primary, Harris, Brent T., primary, Hwang, Eugene I., primary, Lulla, Rishi, primary, Pfister, Stefan M., primary, Achatz, Maria Isabel, primary, Jabado, Nada, primary, Finlay, Jonathan L., primary, Weksberg, Rosanna, primary, Bouffet, Eric, primary, Hawkins, Cynthia, primary, Taylor, Michael D., primary, Tabori, Uri, primary, Ellison, David W., primary, Gilbertson, Richard J., primary, and Malkin, David, primary

Published
2023
Full Text
View/download PDF

45. Appendix from Molecular Characterization of Choroid Plexus Tumors Reveals Novel Clinically Relevant Subgroups

Author

Merino, Diana M., primary, Shlien, Adam, primary, Villani, Anita, primary, Pienkowska, Malgorzata, primary, Mack, Stephen, primary, Ramaswamy, Vijay, primary, Shih, David, primary, Tatevossian, Ruth, primary, Novokmet, Ana, primary, Choufani, Sanaa, primary, Dvir, Rina, primary, Ben-Arush, Myran, primary, Harris, Brent T., primary, Hwang, Eugene I., primary, Lulla, Rishi, primary, Pfister, Stefan M., primary, Achatz, Maria Isabel, primary, Jabado, Nada, primary, Finlay, Jonathan L., primary, Weksberg, Rosanna, primary, Bouffet, Eric, primary, Hawkins, Cynthia, primary, Taylor, Michael D., primary, Tabori, Uri, primary, Ellison, David W., primary, Gilbertson, Richard J., primary, and Malkin, David, primary

Published
2023
Full Text
View/download PDF

46. supplemental figure and table legend from Molecular Characterization of Choroid Plexus Tumors Reveals Novel Clinically Relevant Subgroups

Author

Merino, Diana M., primary, Shlien, Adam, primary, Villani, Anita, primary, Pienkowska, Malgorzata, primary, Mack, Stephen, primary, Ramaswamy, Vijay, primary, Shih, David, primary, Tatevossian, Ruth, primary, Novokmet, Ana, primary, Choufani, Sanaa, primary, Dvir, Rina, primary, Ben-Arush, Myran, primary, Harris, Brent T., primary, Hwang, Eugene I., primary, Lulla, Rishi, primary, Pfister, Stefan M., primary, Achatz, Maria Isabel, primary, Jabado, Nada, primary, Finlay, Jonathan L., primary, Weksberg, Rosanna, primary, Bouffet, Eric, primary, Hawkins, Cynthia, primary, Taylor, Michael D., primary, Tabori, Uri, primary, Ellison, David W., primary, Gilbertson, Richard J., primary, and Malkin, David, primary

Published
2023
Full Text
View/download PDF

47. Table S1-S3 from Molecular Characterization of Choroid Plexus Tumors Reveals Novel Clinically Relevant Subgroups

Author

Merino, Diana M., primary, Shlien, Adam, primary, Villani, Anita, primary, Pienkowska, Malgorzata, primary, Mack, Stephen, primary, Ramaswamy, Vijay, primary, Shih, David, primary, Tatevossian, Ruth, primary, Novokmet, Ana, primary, Choufani, Sanaa, primary, Dvir, Rina, primary, Ben-Arush, Myran, primary, Harris, Brent T., primary, Hwang, Eugene I., primary, Lulla, Rishi, primary, Pfister, Stefan M., primary, Achatz, Maria Isabel, primary, Jabado, Nada, primary, Finlay, Jonathan L., primary, Weksberg, Rosanna, primary, Bouffet, Eric, primary, Hawkins, Cynthia, primary, Taylor, Michael D., primary, Tabori, Uri, primary, Ellison, David W., primary, Gilbertson, Richard J., primary, and Malkin, David, primary

Published
2023
Full Text
View/download PDF

48. Supplemental Tables 1-6 from Tumor-Associated Macrophages in SHH Subgroup of Medulloblastomas

Author

Margol, Ashley S., primary, Robison, Nathan J., primary, Gnanachandran, Janahan, primary, Hung, Long T., primary, Kennedy, Rebekah J., primary, Vali, Marzieh, primary, Dhall, Girish, primary, Finlay, Jonathan L., primary, Erdreich-Epstein, Anat, primary, Krieger, Mark D., primary, Drissi, Rachid, primary, Fouladi, Maryam, primary, Gilles, Floyd H., primary, Judkins, Alexander R., primary, Sposto, Richard, primary, and Asgharzadeh, Shahab, primary

Published
2023
Full Text
View/download PDF

49. Supplemental Methods and Supplemental Figures 1-9 from Tumor-Associated Macrophages in SHH Subgroup of Medulloblastomas

Author

Margol, Ashley S., primary, Robison, Nathan J., primary, Gnanachandran, Janahan, primary, Hung, Long T., primary, Kennedy, Rebekah J., primary, Vali, Marzieh, primary, Dhall, Girish, primary, Finlay, Jonathan L., primary, Erdreich-Epstein, Anat, primary, Krieger, Mark D., primary, Drissi, Rachid, primary, Fouladi, Maryam, primary, Gilles, Floyd H., primary, Judkins, Alexander R., primary, Sposto, Richard, primary, and Asgharzadeh, Shahab, primary

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results