Search

Your search keyword '"Finazzi S"' showing total 194 results
Start Over Author "Finazzi S"
194 results on '"Finazzi S"'

2. One-year survival and Quality of Life of first wave COVID-19 invasively ventilated patients in Lombardy, Italy

Author

Lorini, L, Labanca, R, Bugada, D, Cazzaniga, S, D'Amico, F, Grazioli, L, Marmiere, M, Novelli, L, Pozzi, M, Rona, R, Giani, M, Bellin, V, Lucchini, A, Raimondi, F, Rocchi, M, Salvioni, M, Foti, G, Landoni, G, Andreossi, M, Annoni, A, Azzolini, M, Baiardo Redaelli, M, Belletti, A, Belmonte, G, Benigni, A, Benini, A, Bonfanti, P, Borghi, G, Butovska, L, Cadone Ughi, E, Calabria, M, Celona, S, Ciceri, F, Consalvo, L, Farina, A, Ferlicca, D, Finazzi, S, Fominskiy, E, Grieco, S, Guzzo, F, Landini, S, Lo-Catelli, S, Lorini, A, Lorini, G, Magri, F, Manildo, E, Nava, C, Ortalda, A, Palumbo, D, Real, G, Rezoagli, E, Ripa, C, Saracino, M, Sosio, S, Trocchia, R, Villa, M, Zangrillo, A, Lorini L. F., Labanca R., Bugada D., Cazzaniga S., D'Amico F., Grazioli L., Marmiere M., Novelli L., Pozzi M., Rona R., Giani M., Bellin V., Lucchini A., Raimondi F., Rocchi M., Salvioni M. T., Foti G., Landoni G., Andreossi M., Annoni A., Azzolini M. L., Baiardo Redaelli M., Belletti A., Belmonte G., Benigni A., Benini A., Bonfanti P., Borghi G., Butovska L., Cadone Ughi E., Calabria M., Celona S., Ciceri F., Consalvo L., Farina A., Ferlicca D., Finazzi S., Fominskiy E. V., Grieco S., Guzzo F., Landini S., Lo-Catelli S., Lorini A., Lorini G., Magri F., Manildo E., Nava C., Ortalda A., Palumbo D., Real G., Rezoagli E., Ripa C., Saracino M., Sosio S., Trocchia R., Villa M., Zangrillo A., Lorini, L, Labanca, R, Bugada, D, Cazzaniga, S, D'Amico, F, Grazioli, L, Marmiere, M, Novelli, L, Pozzi, M, Rona, R, Giani, M, Bellin, V, Lucchini, A, Raimondi, F, Rocchi, M, Salvioni, M, Foti, G, Landoni, G, Andreossi, M, Annoni, A, Azzolini, M, Baiardo Redaelli, M, Belletti, A, Belmonte, G, Benigni, A, Benini, A, Bonfanti, P, Borghi, G, Butovska, L, Cadone Ughi, E, Calabria, M, Celona, S, Ciceri, F, Consalvo, L, Farina, A, Ferlicca, D, Finazzi, S, Fominskiy, E, Grieco, S, Guzzo, F, Landini, S, Lo-Catelli, S, Lorini, A, Lorini, G, Magri, F, Manildo, E, Nava, C, Ortalda, A, Palumbo, D, Real, G, Rezoagli, E, Ripa, C, Saracino, M, Sosio, S, Trocchia, R, Villa, M, Zangrillo, A, Lorini L. F., Labanca R., Bugada D., Cazzaniga S., D'Amico F., Grazioli L., Marmiere M., Novelli L., Pozzi M., Rona R., Giani M., Bellin V., Lucchini A., Raimondi F., Rocchi M., Salvioni M. T., Foti G., Landoni G., Andreossi M., Annoni A., Azzolini M. L., Baiardo Redaelli M., Belletti A., Belmonte G., Benigni A., Benini A., Bonfanti P., Borghi G., Butovska L., Cadone Ughi E., Calabria M., Celona S., Ciceri F., Consalvo L., Farina A., Ferlicca D., Finazzi S., Fominskiy E. V., Grieco S., Guzzo F., Landini S., Lo-Catelli S., Lorini A., Lorini G., Magri F., Manildo E., Nava C., Ortalda A., Palumbo D., Real G., Rezoagli E., Ripa C., Saracino M., Sosio S., Trocchia R., Villa M., and Zangrillo A.

Abstract

BACKGROUND: Lombardy was the epicenter of the first coronavirus disease 2019 (COVID-19) outbreak in western countries. The outbreak began in February 2020 and rapidly disseminated throughout the region. ICU beds were vastly insufficient and clinical knowledge of disease was poor at that time. Unfortunately, data on long-term mortality, morbidity, and Quality of Life are scarce and controversial. The aim of this study was to evaluate 1-year survival, Quality of Life, and functional recovery in patients with COVID-19 admitted to Intensive Care Units. METHODS: All COVID-19 patients invasively ventilated and successfully discharged from 3 important academic hospitals in Lombardy were evaluated. Evaluations were performed by qualified medical staff and monitoring over time was performed by telephone call. Functional, cognitive, and psychological outcomes were explored using validated questionnaires. Selected patients were offered a follow-up chest computed tomography (CT) scan. RESULTS: Four hundred twenty-seven patients were invasively ventilated and 268 (63%) were successfully discharged. Out of these 268 patients, 266 (99%) were alive at one year with no patient loss during follow-up. Very severe or severe dyspnea was reported by 7% of patients, while most patients (84%) did not experience dyspnea at rest. A small proportion of patients (17%) reported severe anxiety/depression. Good Quality of Life was reported by 64% of survivors. In patients complaining of dyspnea on exertion, fibrotic-like changes were observed at chest CT scans in 32/37 (86%) and 7/11 (63%) patients who underwent CT at 3 months and 1 year, respectively. CONCLUSIONS: COVID-19 patients discharged from the hospital after invasive ventilation had excellent one-year survival and good overall recovery and Quality of Life.

Published
2024

4. Time-dependent study of a black-hole laser in a flowing atomic condensate

Author

de Nova, J. R. M., Finazzi, S., and Carusotto, I.

Subjects
Condensed Matter - Quantum Gases, General Relativity and Quantum Cosmology, Nonlinear Sciences - Pattern Formation and Solitons
Abstract

We numerically study the temporal evolution of a black-hole laser configuration displaying a pair of black and white hole horizons in a flowing atomic condensate. This configuration is initially prepared starting from a homogeneous flow via a suitable space-dependent change of the interaction constant and the evolution is then followed up to long times. Depending on the values of the system parameters, the system typically either converges to the lowest energy solution by evaporating away the horizons or displays a continuous and periodic coherent emission of solitons. By making a physical comparison with optical laser devices, we identify the latter regime of continuous emission of solitons as the proper black-hole laser effect. We include some movies of the temporal evolution of the spatial density and velocity profiles in the most significant cases., Comment: 14 pages, 5 figures, 12 videos

Published
2015
Full Text
View/download PDF

5. Corner space renormalization method for driven-dissipative 2D correlated systems

Author

Finazzi, S., Boité, A. Le, Storme, F., Baksic, A., and Ciuti, C.

Subjects
Quantum Physics, Condensed Matter - Quantum Gases
Abstract

We present a theoretical method to study driven-dissipative correlated systems on lattices with two spatial dimensions (2D). The steady-state density-matrix of the lattice is obtained by solving the master equation in a corner of the Hilbert space. The states spanning the corner space are determined through an iterative procedure, using eigenvectors of the density-matrix of smaller lattice systems, merging in real space two lattices at each iteration and selecting M pairs of states by maximizing their joint probability. Accuracy of the results is then improved by increasing M, the number of states of the corner space, until convergence is reached. We demonstrate the efficiency of such an approach by applying it to the driven-dissipative 2D Bose-Hubbard model, describing, e.g., lattices of coupled cavities with quantum optical nonlinearities.

Published
2015
Full Text
View/download PDF

6. Instability of the superfluid flow as black-hole lasing effect

Author

Finazzi, S., Piazza, F., Abad, M., Smerzi, A., and Recati, A.

Subjects
Condensed Matter - Quantum Gases, General Relativity and Quantum Cosmology
Abstract

We show that the instability leading to the decay of the one-dimensional superfluid flow through a penetrable barrier are due to the black-hole lasing effect. This dynamical instability is triggered by modes resonating in an effective cavity formed by two horizons enclosing the barrier. The location of the horizons is set by $v(x)=c(x)$, with $v(x),c(x)$ being the local fluid velocity and sound speed, respectively. We compute the critical velocity analytically and show that it is univocally determined by the horizons configuration. In the limit of broad barriers, the continuous spectrum at the origin of the Hawking-like radiation and of the Landau energetic instability is recovered., Comment: 18 pages, 3 figures

Published
2014
Full Text
View/download PDF

7. SARS-CoV-2 breakthrough infections in vaccinated individuals requiring ventilatory support for severe acute respiratory failure

Author

Finazzi, S, Perego, M, Tricella, G, Poole, D, Ranieri, V, Rizzo, C, Fumagalli, R, Antonella, J, Nicola, P, Andrea, D, Rita, T, Francesco, C, Manuela, B, Francesca, C, Romano, G, Vieri, P, Giampiero, B, Stefano, F, Rita, C, Monica, G, Omar, A, Loredana, F, Riccardo, G, Alessandra, P, Dino, D, Cleto, A, Paolo, M, Manuela, C, Andrea, B, Maria, B, Gianluca, Z, Michela, Z, Alessandro, M, Mario, P, Alic, P, Finazzi S., Perego M., Tricella G., Poole D., Ranieri V. M., Rizzo C., Fumagalli R., Antonella J., Nicola P., Andrea D. S., Rita T., Francesco C., Manuela B., Francesca C. F., Romano G., Vieri P., Giampiero B., Stefano F., Rita C., Monica G., Omar A., Loredana F., Riccardo G., Alessandra P., Dino D. P., Cleto A., Paolo M., Manuela C., Andrea B., Maria B., Gianluca Z., Michela Z., Alessandro M., Mario P., Alic P., Finazzi, S, Perego, M, Tricella, G, Poole, D, Ranieri, V, Rizzo, C, Fumagalli, R, Antonella, J, Nicola, P, Andrea, D, Rita, T, Francesco, C, Manuela, B, Francesca, C, Romano, G, Vieri, P, Giampiero, B, Stefano, F, Rita, C, Monica, G, Omar, A, Loredana, F, Riccardo, G, Alessandra, P, Dino, D, Cleto, A, Paolo, M, Manuela, C, Andrea, B, Maria, B, Gianluca, Z, Michela, Z, Alessandro, M, Mario, P, Alic, P, Finazzi S., Perego M., Tricella G., Poole D., Ranieri V. M., Rizzo C., Fumagalli R., Antonella J., Nicola P., Andrea D. S., Rita T., Francesco C., Manuela B., Francesca C. F., Romano G., Vieri P., Giampiero B., Stefano F., Rita C., Monica G., Omar A., Loredana F., Riccardo G., Alessandra P., Dino D. P., Cleto A., Paolo M., Manuela C., Andrea B., Maria B., Gianluca Z., Michela Z., Alessandro M., Mario P., and Alic P.

Published
2023

9. Persistent currents in two-component condensates in a toroidal trap

Author

Abad, M., Sartori, A., Finazzi, S., and Recati, A.

Subjects
Condensed Matter - Quantum Gases
Abstract

The stability of persistent currents in a two-component Bose-Einstein condensate in a toroidal trap is studied both in the miscible and immiscible regimes. In the miscible regime we show that superflow decay is related to linear instabilities of the spin-density Bogoliubov mode. We find a region of partial stability, where the flow is stable in the majority component while it decays in the minority component. We also characterize the dynamical instability appearing for a large relative velocity between the two components. In the immiscible regime the stability criterion is modified and depends on the specific density distribution of the two components. The effect of a coherent coupling between the two components is also discussed., Comment: 11 pages, 8 figures

Published
2013
Full Text
View/download PDF

12. The prognostic importance of chronic end-stage diseases in geriatric patients admitted to 163 Italian ICUs

Author

Poole, D., Finazzi, S., Nattino, G., Radrizzani, D., Gristina, G., Malacarne, P., Livigni, S., Bertolini, G., Sorgato, C., Mannoni, R., Agnelli, V., Chiani, C., Lanza, G., Venturini, E., Gianni, M., Olivieri, M. C., Guerriero, B., Della Mora, E., Palmer, M., Blasetti, A., Coletta, R., Covani Frigieri, F., Guarducci, M. D., Caracciolo, A., Lain, G., Bernard, M., DE Blasio, E., Zanni, V., Marchesi, G., Madeira, S. M., Spagarino, E., Potalivo, A., Mengoli, F., Parrini, V., Sagliaschi, U., Prandini, A., Rosano, A., Natalini, G., Piccioni, G., Schiavuzzi, M., Bronzini, N., Piva, S., Besozzi, A., Napoleone, A., Patrignani, L., Pisu, M., Mancosu, S., Chiarello, M., Pastorini, S., Bassi, G., Negro, G., Orsini, I., Marifoglou, D., Pota, V., Pegoraro, M., Sucre, M. J., DI Masi, P., Castiglione, G., Morello, G., Garofalo, G., Caroleo, S., Visconti, M. G., Gamberini, E., Mastroianni, A., Liccardi, M. M., Anelati, D., Martinelli, S., Bonato, A., Adorni, A., Colombo, D., Dal Cero, P., Crema, L., Petrucci, N., Beck, E., Alleva, S., Giuntini, R., DA Re, D., Casalini, P., Fabi, M. C., Galeotti, E., Bagalini, G., Bellonzi, A., Zoppellari, R., Lamborghini, S., Pera, L., Doni, L., Bonizzoli, M., Librenti, M., Barattini, M., Mangani, V., Terzitta, M., Guagliardi, C., Bruzzone, C., Arditi, E., Cerana, M., Tavola, M., Falini, S., Vespignani, M. G., Salvi, G., Ramello, P. L., Molesi, A., Ceradelli, M., Buonanno, R., Righini, E., DI Cocco, A., DI Martino, R., Cinque, E., Bonfiglio, M., Ciceri, R., Colombo, L., Nardini, M., Rossi, G., Boccalatte-Rosa, D. L., Babini, M., Zompanti, V., Negri, G., Antonini, B., Baratta, A., Zuccaro, F., Rossi, M., Pedeferri, M., Bellin, M., Sicignano, A., Pezzi, A., Leggieri, C., Fontana, G., Faraldi, L., Cigada, M. G., Magenta, P., Colombo, R., Colombo, S., Gonzi, S., Pizzali, M., Girardis, M., Piccinini, P., Bignone, P., Padovan, L., Bianchin, A., Caria, F. C., Randellini, R., Roticiani, V., Grassi, M., Belluomo Anello, C., Decristofaro, M., Postiglione, M., Giacomello, S., Olivieri, C., Vaccari, C., Dal Ferro, M., Messina, M., Belgiorno, N., Odetto, L., Pasetti, G. S., Balicco, B., Pizzaballa, M. L., Muraro, L., Pignataro, A., Guadagna, A., Fabbri, P. G., Tetamo, R., Bottazzi, A., Mediani, T. S., Gorietti, A., Breschi, C., Ciani, A., Segalini, P., Codeluppi, V., Berruto, F., Pastorelli, M., Comite, C., Pelati, E., Bertolini, R., Lefons, U., DI Pasquale, D. A., Mannolini, G., Vlassich, F., Becarelli, S., Garelli, A., Salsi, P., Rossi, S., Facondini, F., Alampi, D., Cingolani, E., Molino, F. M., Nardi, G., Casula, M., DE Blasi, R. A., Vulcano, G. A., Azzolini, M., Bernasconi, M. O., Bellato, V., Calicchio, G., Righetti, F., Turati, M., Dei Poli, M., Zaro, G., Brizio, E., Coaloa, M., Falzetti, G., Mamprin, F., Liverani, C. M., Clementi, S., Bonucci, P., Varesio, V., Pannacci, R., Fiore, G., Gallo, M., Torta, M., Selvaggi, P., Bert, P. P., Segala, V., Pettazzi, G., Bensi, M., Bocchi, A., Cima, M., Morbelli, M., Peta, M., DI Stella, R., Maggiolo, C., Lembo, R., Pero, A., Marafon, S., Carnevale, L., Vanzino, R., Vecchiarelli, P., and Marino, G.

Subjects
Male, medicine.medical_specialty, Cirrhosis, Disease, Severity of Illness Index, law.invention, 03 medical and health sciences, 0302 clinical medicine, Patient Admission, Postoperative Complications, law, Internal medicine, 80 and over, aged, critical care, prognosis, Medicine, Dementia, Humans, Hospital Mortality, Elective surgery, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Critical care, Prognosis, Female, Intensive Care Units, Italy, Chronic Disease, 030208 emergency & critical care medicine, Odds ratio, medicine.disease, Comorbidity, Intensive care unit, Anesthesiology and Pain Medicine, 030228 respiratory system, Cohort, business
Abstract

BACKGROUND The number of elderly patients undergoing major surgical interventions and then needing admission to intensive care unit (ICU) grows steadily. We investigated this issue in a cohort of 232,278 patients admitted in five years (2011-2015) to 163 Italian general ICUs. METHODS Surgical patients older than 75 registered in the GiViTI MargheritaPROSAFE project were analyzed. The impact on hospital mortality of important chronic conditions (severe COPD, NYHA class IV, dementia, end-stage renal disease, cirrhosis with portal hypertension) was investigated with two prognostic models developed yearly on patients staying in the ICU less or more than 24 hours. RESULTS 44,551 elderly patients (19.2%) underwent emergency (47.3%) or elective surgery (52.7%). At least one severe comorbidity was present in 14.6% of them, yielding a higher hospital mortality (32.4%, vs. 21.1% without severe comorbidity). In the models for patients staying in the ICU 24 hours or more, cirrhosis, NYHA class IV, and severe COPD were constant independent predictors of death (adjusted odds ratios [ORs] range 1.67-1.97, 1.54-1.91, and 1.34-1.50, respectively), while dementia was statistically significant in four out of five models (adjusted ORs 1.23-1.28). End-stage renal disease, instead, never resulted to be an independent prognostic factor. For patients staying in the ICU less than 24 hours, chronic comorbidities were only occasionally independent predictors of death. CONCLUSIONS Our study confirms that elderly surgical patients represent a relevant part of all ICUs admissions. About one of seven bear at least one severe chronic comorbidity, that, excluding end-stage renal disease, are all strong independent predictors of hospital death.

Published
2017

13. Corner space renormalization method for driven-dissipative 2D correlated systems

Author

Finazzi, S, Le Boité, A, Storme, F, Baksic, A, Ciuti, C, Laboratoire Matériaux et Phénomènes Quantiques (MPQ (UMR_7162)), and Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Quantum Physics, [PHYS.QPHY]Physics [physics]/Quantum Physics [quant-ph], Quantum Gases (cond-mat.quant-gas), FOS: Physical sciences, [PHYS.COND]Physics [physics]/Condensed Matter [cond-mat], Condensed Matter - Quantum Gases, Quantum Physics (quant-ph)
Abstract

We present a theoretical method to study driven-dissipative correlated systems on lattices with two spatial dimensions (2D). The steady-state density-matrix of the lattice is obtained by solving the master equation in a corner of the Hilbert space. The states spanning the corner space are determined through an iterative procedure, using eigenvectors of the density-matrix of smaller lattice systems, merging in real space two lattices at each iteration and selecting M pairs of states by maximizing their joint probability. Accuracy of the results is then improved by increasing M, the number of states of the corner space, until convergence is reached. We demonstrate the efficiency of such an approach by applying it to the driven-dissipative 2D Bose-Hubbard model, describing, e.g., lattices of coupled cavities with quantum optical nonlinearities.

Published
2015

14. Fecal calproctectin and elastase 1 determinations in patients with pancreatic disease: a possible link between pancreatic insufficiency and intestinal inflammation

Author

Pezzilli R., Barassi A., Fantini L., Finazzi S., Melzi D'Eril G., MORSELLI LABATE, ANTONIO MARIA, TOMASSETTI, PAOLA, CAMPANA, DAVIDE, CASADEI, RICCARDO, CORINALDESI, ROBERTO, Pezzilli R., Barassi A., Morselli Labate A.M., Fantini L., Tomassetti P., Campana D., Casadei R., Finazzi S., Melzi D'Eril G., and Corinaldesi R.

Subjects
fluids and secretions, BINDING PROTEINS, PANCREATITIS, CHRONIC PANCREATITIS, LEUKOCYTE L1 ANTIGEN COMPLEX, CALCIUM
Abstract

Background Fecal calprotectin determination has been demonstrated to be useful in diagnosing various inflammatory diseases of the gastrointestinal tract; however, data available for patients with pancreatic diseases are scarce. Our aim was to assess fecal calprotectin in order to evaluate the presence of intestinal inflammation in patients with pancreatic disease. Methods Eligible patients with suspected pancreatic illness were enrolled, and in all of them fecal calprotectin and elastase-1, as well as serum amylase and lipase activities, were assayed using commercially available kits. Results A total of 90 subjects (47 men, 43 women, mean age 58.6 ± 14.9 years) were enrolled: 20 (22.2%) had chronic pancreatitis; 15 (16.7%) had pancreatic cancer; six (6.7%) had chronic nonpathological pancreatic hyperenzymemia; 16 (17.8%) had nonpancreatic diseases; and 23 (25.6%) had no detectable diseases. Diarrhea was present in 19 patients (21.1%). In univariate analyses, the presence of diarrhea and low fecal elastase-1 concentrations were significantly associated (P = 0.019 and P = 0.002, respectively) with abnormally high fecal calprotectin concentration, and the multivariate analysis demonstrated that low fecal elastase-1 concentration was the only variable independently associated with a high fecal calprotectin concentration. Conclusions Pancreatic insufficiency may cause intestinal inflammation, probably because of a modification of the intestinal ecology.

Published
2007

41. Calibration belt for quality-of-care assessment based on dichotomous outcomes

Author

Finazzi, S, Poole, D, Luciani, D, Cogo, P, Bertolini, G, Bertolini, G., LUCIANI, DAVIDE, Finazzi, S, Poole, D, Luciani, D, Cogo, P, Bertolini, G, Bertolini, G., and LUCIANI, DAVIDE

Abstract

Prognostic models applied in medicine must be validated on independent samples, before their use can be recommended. The assessment of calibration, i.e., the model's ability to provide reliable predictions, is crucial in external validation studies. Besides having several shortcomings, statistical techniques such as the computation of the standardized mortality ratio (SMR) and its confidence intervals, the Hosmer-Lemeshow statistics, and the Cox calibration test, are all non-informative with respect to calibration across risk classes. Accordingly, calibration plots reporting expected versus observed outcomes across risk subsets have been used for many years. Erroneously, the points in the plot (frequently representing deciles of risk) have been connected with lines, generating false calibration curves. Here we propose a methodology to create a confidence band for the calibration curve based on a function that relates expected to observed probabilities across classes of risk. The calibration belt allows the ranges of risk to be spotted where there is a significant deviation from the ideal calibration, and the direction of the deviation to be indicated. This method thus offers a more analytical view in the assessment of quality of care, compared to other approaches. © 2011 Finazzi et al.

Published
2011

Catalog

Books, media, physical & digital resources
See catalog results