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18. Vingt-quatrième réunion du comité local de la Société de pathologie exotique, 18 mars 2014

Author

Gaüzère, B.-A., Malvy, D., Aubry, P., Brottet, E., Jaffar-Bandjee, M.-C., Filleul, L., Vandroux, D., Jabot, J., Angue, M., Belcour, D., Bouchet, B., Chanareille, P., Gauvin, T., Rakotoarisoa, A., Halm, A., Rakotomanga, L. M., Randrianarivo-Solofoniaina, A. E., Champion, S., Lefort, Y., Durasnel, P., Lion, F., Blondé, R., Valyi, L., Allyn, J., and Martinet, O.

Published
2014
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39. Mise en place d&8217;une surveillance spatialisée des malformations congénitales à La Réunion : choix méthodologiques

Author

Randrianaivo H., Bertaut-Nativel, B., André, M., Irabe, M., Robillard, P.Y., Boumahni, B., Mangeas, Morgan, Roux, Emmanuel, Yao Brou, Télesphore, Gérardin, P., Filleul, L., and Herbreteau, Vincent

Subjects
MEDECINE, SYSTEME D'INFORMATION GEOGRAPHIQUE, MALFORMATION CONGENITALE, SURVEILLANCE, SANTE PUBLIQUE, PREVALENCE, GEOLOCALISATION
Abstract

Introduction: Le Registre des malformations congénitales de La Réunion (Remacor) assure la surveillance de ces pathologies à des fins de santé publique et de recherche. Cette surveillance consiste en un recueil exhaustif des cas et en l'analyse temporelle de leur survenue. Afin de permettre leur analyse spatiale et la détection de signaux sanitaires, le Remacor a géocodé rétroactivement les données et mis en place une surveillance spatialisée, dont les choix méthodologiques sont présentés ici. Matériel et méthodes: Chaque cas est géolocalisé conformément à l'adresse de la mère. Les prévalences relatives aux naissances sont ensuite calculées par agrégation des cas selon les différentes échelles administratives. Le choix de l'échelle est déterminé à l'aide d'un test de Poisson qui permet d'estimer le nombre de naissances minimum nécessaire pour réaliser l'analyse de manière statistiquement significative, puis d'un compromis entre cette significativité de l'information, la complétude des données et la résolution spatiale. Résultats: Il a été possible de géolocaliser 95% des cas. Différentes méthodes de détection d'agrégats de cas ont été utilisées afin de repérer les zones les plus touchées. Enfin, les agrégats détectés à différentes échelles ont été intersectés pour calculer un indice d'appartenance à 1, 2 ou 3 échelles. Discussion et conclusion: La base de données spatialisée mise en place permet aujourd'hui au Remacor de prendre en compte l'hétérogénéité spatiale de la distribution des malformations congénitales les plus fréquentes pour informer les acteurs de la santé publique.

Published
2017

43. Emergence of dengue virus serotype 3 on Mayotte Island, Indian Ocean

Author

Lernout T, Giry C, Binder P, Zumbo B, Durquety E, Lajoinie G, Eric D'Ortenzio, and Filleul L

Subjects
Dengue, Immunoglobulin M, Aedes, Seroepidemiologic Studies, Immunoglobulin G, Animals, Humans, Dengue Virus, Antibodies, Viral, Communicable Diseases, Emerging, Sentinel Surveillance, Comoros, Disease Outbreaks
Abstract

A serosurvey carried out in 2006 in Mayotte, a French overseas collectivity in the Indian Ocean, confirmed previous circulation of dengue virus (DENV) on the island, but since the set up of a laboratory-based surveillance of dengue-like illness in 2007, no case of DENV has been confirmed. In response to an outbreak of DENV-3 on Comoros Islands in March 2010 surveillance of dengue-like illness in Mayotte was enhanced. By September 15, 76 confirmed and 31 probable cases of DENV have been identified in Mayotte. In urban andperiurban settings on the island, Aedes albopictus is the predominant Aedes species, but Ae. aegyptii remains the most common species in rural areas. Given the epidemic potential of dengue virus in Mayotte, adequate monitoring including early detection of cases, timely investigation and sustained mosquito control actions remain essential.

Published
2011

44. Agrégats spatiotemporels de cancers en milieu professionnel : réponse de santé publique par l’Institut de veille sanitaire (InVS) – apport et limite de l’épidémiologie d’investigation

Author

Empereur-Bissonnet, P., primary, Fréry, N., additional, Provost, D., additional, Saura, C., additional, Brière, J., additional, Buisson, C., additional, Berneron, B., additional, Garnier, R., additional, Castor, C., additional, Filleul, L., additional, Poujol, I., additional, Pilorget, C., additional, Gault, G., additional, Lapostolle, A., additional, and Rolland, P., additional

Published
2015
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45. Investigation of a leptospirosis outbreak in triathlon participants, Réunion Island, 2013

Author

PAGÈS, F., primary, LARRIEU, S., additional, SIMOES, J., additional, LENABAT, P., additional, KURTKOWIAK, B., additional, GUERNIER, V., additional, LE MINTER, G., additional, LAGADEC, E., additional, GOMARD, Y., additional, MICHAULT, A., additional, JAFFAR-BANDJEE, M. C., additional, DELLAGI, K., additional, PICARDEAU, M., additional, TORTOSA, P., additional, and FILLEUL, L., additional

Published
2015
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48. Emergence of murine typhus in Reunion Island, South West Ocean Indian Island: Epidemiological, clinical, laboratory features of 10 cases

Author

Balleydier, E., primary, Camuset, G., additional, Socolovsci, C., additional, Moiton, M.P., additional, Kuli, B., additional, Foucher, A., additional, Poubeau, P., additional, Borgherini, G., additional, Wartel, G., additional, Audin, H., additional, Parola, P., additional, Raoult, D., additional, Pagès, F., additional, and Filleul, L., additional

Published
2014
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50. Pandemic Influenza Due to pH1N1/2009 Virus: Estimation of Infection Burden in Reunion Island through a Prospective Serosurvey, Austral Winter 2009

Author

Dellagi, K, Rollot, O, Temmam, S, Salez, N, Guernier, Vanina, Pascalis, H, Gerardin, P, Fianu, A, Lapidus, N, Naty, N, Tortosa, P, Boussaid, K, Jaffar-Banjee, M-C, Filleul, L, Flahault, A, Carrat, F, Favier, F, de Lamballerie, X, Dellagi, K, Rollot, O, Temmam, S, Salez, N, Guernier, Vanina, Pascalis, H, Gerardin, P, Fianu, A, Lapidus, N, Naty, N, Tortosa, P, Boussaid, K, Jaffar-Banjee, M-C, Filleul, L, Flahault, A, Carrat, F, Favier, F, and de Lamballerie, X

Abstract

Background To date, there is little information that reflects the true extent of spread of the pH1N1/2009v influenza pandemic at the community level as infection often results in mild or no clinical symptoms. This study aimed at assessing through a prospective study, the attack rate of pH1N1/2009 virus in Reunion Island and risk factors of infection, during the 2009 season. Methodology/Principal Findings A serosurvey was conducted during the 2009 austral winter, in the frame of a prospective population study. Pairs of sera were collected from 1687 individuals belonging to 772 households, during and after passage of the pandemic wave. Antibodies to pH1N1/2009v were titered using the hemagglutination inhibition assay (HIA) with titers ≥1/40 being considered positive. Seroprevalence during the first two weeks of detection of pH1N1/2009v in Reunion Island was 29.8% in people under 20 years of age, 35.6% in adults (20–59 years) and 73.3% in the elderly (≥60 years) (P<0.0001). Baseline corrected cumulative incidence rates, were 42.9%, 13.9% and 0% in these age groups respectively (P<0.0001). A significant decline in antibody titers occurred soon after the passage of the epidemic wave. Seroconversion rates to pH1N1/2009 correlated negatively with age: 63.2%, 39.4% and 16.7%, in each age group respectively (P<0.0001). Seroconversion occurred in 65.2% of individuals who were seronegative at inclusion compared to 6.8% in those who were initially seropositive. Conclusions Seroincidence of pH1N1/2009v infection was three times that estimated from clinical surveillance, indicating that almost two thirds of infections occurring at the community level have escaped medical detection. People under 20 years of age were the most affected group. Pre-epidemic titers ≥1/40 prevented seroconversion and are likely protective against infection. A concern was raised about the long term stability of the antibody

Published
2011

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