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240 results on '"Figueiredo, Fabiano Borges"'

1. Comparative study of colorimetric in situ hybridization and quantitative real-time polymerase chain reaction for diagnosis of infection by 'Leishmania infantum' in dogs in formalin-fixed and paraffin-embedded skin

Author

Silva, Ricardo Goncalves, Kiupel, Matti, Langohr, Ingeborg Maria, Wise, Annabel, Pereira, Sandro Antonio, Goncalves, Natalia Pedra, da Conceicao, Greice Maria Silva, Ferreira, Luiz Claudio, de Campos, Monique Paiva, de Freitas Campos Miranda, Luciana, Figueiredo, Fabiano Borges, de Vasconcellos Carvalhaes de Oliveira, Raquel, Keidel, Lucas, and Menezes, Rodrigo Caldas

Published
2024

2. Seropositivity of anti-'Toxoplasma gondii' antibodies in owners and their dogs living on Island and mainland seashore areas of Southern Brazil

Author

Freitas, Aaronson Ramathan, Delai, Ruana Renostro, Kmetiuk, Louise Bach, da Silva, Evelyn Cristine, Martini, Rafaella, Brandao, Ana Perola Drulla, Giuffrida, Rogerio, Barros-Filho, Ivan Roque de, Costa da Silva, Rodrigo, Langoni, Helio, Figueiredo, Fabiano Borges, Pimpao, Claudia Turra, Santos, Andrea Pires Dos, Santarem, Vamilton Alvares, and Biondo, Alexander Welker

Published
2022

4. Factors associated with adherence to the principles of responsible companion animal guardianship in a municipality in southeastern Brazil

Author

Penaforte, Klauber Menezes, da Silva, Eduardo Sérgio, de Melo, Saulo Nascimento, Soares, Paulo Henrique Araújo, Gonçalves, Cláudia Maria de Souza, Ribeiro, Renata Aparecida Nascimento, Horta, Marco Aurélio Pereira, Lélis, Sarah de Faria, Silveira, Clara Guimarães, Figueiredo, Fabiano Borges, Teixeira-Neto, Rafael Gonçalves, and Belo, Vinícius Silva

Published
2024
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5. Bartonella spp. and Typhus Group Rickettsiae among Persons Experiencing Homelessness, Sao Paulo, Brazil

Author

Faccini-Martinez, Alvaro A., Kmetiuk, Louise Bach, Blanton, Lucas S., Felipetto, Lais Giuliane, Gravinatti, Mara Lucia, Timenetsky, Jorge, Goncalves, Luiz Ricardo, Machado, Rosangela Zacarias, Andre, Marcos Rogerio, Figueiredo, Fabiano Borges, dos Santos, Andrea Pires, Labruna, Marcelo B., Monti, Gustavo, Biondo, Alexander Welker, and Walker, David H.

Subjects
São Paulo, Brazil (City) -- Health aspects, Homeless persons -- Health aspects -- Statistics, Rickettsiales infections -- Risk factors -- Demographic aspects -- Statistics, Health
Abstract

Persons experiencing homelessness might be predisposed to vectorborne infections because of increased exposure to ectoparasites (1). Members of the genera Bartonella and Rickettsia, particularly the louseborne pathogens B. quintana and [...]

Published
2023
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8. In Vitro Evaluation of the Combinatorial Effect of Naringenin and Miltefosine against Leishmania amazonensis.

Author

Lessa, Vinícius Lopes, Gonçalves, Gustavo, Santos, Beatriz, Cavalari, Victoria Cruz, da Costa Vieira, Rafael Felipe, and Figueiredo, Fabiano Borges

Subjects
CUTANEOUS leishmaniasis, MILTEFOSINE, FOOD additives, DRUG toxicity, DOSAGE forms of drugs
Abstract

Leishmania amazonensis causes a clinical form called diffuse cutaneous leishmaniasis (DCL) with challenges to treatment, like low efficiency and drug toxicity. Therefore, it is necessary to investigate new therapies using less toxic leishmanicidal compounds, such as flavonoids like naringenin, and their combination with conventional drugs, such as miltefosine. Antileishmanial dose/response activity, isobologram, calculation of dose reduction index (DRI), and fractional inhibitory concentration index (FICI) tests were performed on in vitro assays using reference promastigote forms of L. amazonensis (IFLA/BR/67/PH8) to assess the combinatorial effect between naringenin and miltefosine. The in vitro results of isobologram, DRI, and FICI calculations showed that the combination of the compounds had an additive effect and was able to reduce the half maximal inhibitory concentration (IC50) of miltefosine in the promastigote forms of the parasite compared to the treatment of the drug alone. This study demonstrated in vitro the viability of a combination action of the flavonoid with the treatment with miltefosine, opening space for further investigations on the association of natural compounds with the drugs used for the treatment of L. amazonensis. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Frequency of detection and load of amastigotes in the pancreas of Leishmania infantum-seropositive dogs: clinical signs and histological changes

Author

Kost, William de Oliveira, Pereira, Sandro Antonio, Figueiredo, Fabiano Borges, Mendes Junior, Artur Augusto Velho, Madeira, Maria de Fátima, Miranda, Luciana de Freitas Campos, de Oliveira, Raquel de Vasconcellos Carvalhaes, Ferreira, Luiz Cláudio, Morgado, Fernanda Nazaré, and Menezes, Rodrigo Caldas

Published
2021
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18. Serological survey of leptospirosis in horses with historical displacement through different geographic regions in Brazil

Author

De Vasconcelos, Tassia Cristina Bello, primary, De Castro, Marina Pinheiro, additional, Da Silva, Daniela Barbosa, additional, Barros, Renata Simões, additional, De Almeida, Adilson Benedito, additional, Mendes Júnior, Artur Augusto Velho, additional, Langoni, Helio, additional, and Figueiredo, Fabiano Borges, additional

Published
2023
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21. A case of canine visceral leishmaniasis of unknown origin in Curitiba (state of Paraná, Brazil) treated successfully with miltefosine

Author

Gonçalves, Gustavo, primary, Campos, Monique Paiva, additional, Tirado, Thais Cristina, additional, Negrão, Dayane Domingos, additional, Silva, Gabriela Mayoral Pedroso da, additional, Poleto, Ana Paula Coninck Mafra, additional, Hartin, Tatianna Paula, additional, Silva, Juliana Batista Andrade, additional, Castilhos, Marilia de Melo Santos de, additional, and Figueiredo, Fabiano Borges, additional

Published
2023
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22. Pro-Cellular Exhaustion Markers are Associated with Splenic Microarchitecture Disorganization and Parasite Load in Dogs with Visceral Leishmaniasis

Author

de Souza, Tainã Luís, da Silva, Aurea Virginia Andrade, Pereira, Luiza de Oliveira Ramos, Figueiredo, Fabiano Borges, Mendes Junior, Artur Augusto Velho, Menezes, Rodrigo Caldas, Mendes-da-Cruz, Daniella Areas, Boité, Mariana Côrtes, Cupolillo, Elisa, Porrozzi, Renato, and Morgado, Fernanda Nazaré

Published
2019
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24. Epidemiology of Rickettsia spp. in Atlantic rainforest areas of island and seashore mainland, southern Brazil

Author

Kmetiuk, Louise Bach, primary, Paula, Warley Vieira de Freitas, additional, Pádua, Gracielle Teles, additional, Delai, Ruana Renostro, additional, Freitas, Aaronson Ramathan, additional, Farinhas, João Henrique, additional, de Paula, Luiza Gabriella Ferreira, additional, Giuffrida, Rogério, additional, Pimpão, Claudia Turra, additional, Álvares Santarém, Vamilton, additional, dos Santos, Andrea Pires, additional, Figueiredo, Fabiano Borges, additional, Krawczak, Felipe da Silva, additional, and Biondo, Alexander Welker, additional

Published
2022
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25. Parasite load, iNOS and cytokine profiles, and histopathological aspects of Leishmania infantum infection in dogs with different clinical presentations/Carga Parasitaria, iNOS, citocinas e histopatologia na infeccao por Leishmania infantum em caes com apresentacoes clinicas distintas

Author

de Vasconcelos, Tassia Cristina Bello, Bruno, Savio Freire, de Miranda, Luisa Helena Monteiro, Conceicao-Silva, Fatima, Belo, Vinicius Silva, and Figueiredo, Fabiano Borges

Published
2019
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26. Posibilidades terapéuticas para el tratamiento de la Leishmaniosis Visceral Canina en Brasil: Revisión de la literatura

Author

Krolow, Mariana Timm, Gomes, Mariana Reis, Versteg, Nielle, Waller, Stefanie Bressan, Figueiredo, Fabiano Borges, Cleff, Marlete Brum, and Dias, Tábata Pereira

Subjects
Zoonose, Novas terapias, Fármacos, Medicamentos, Nuevas terapias, Drugs, Zoonosis, New therapies, L. infantum
Abstract

Canine Visceral Leishmaniasis (CVL) is considered an endemic disease in several regions of Brazil, being the focus of several public policies because of its zoonotic potential. The only medication regulated by the Ministry of Agriculture, Livestock and Supply (MAPA) in the country for the treatment of the disease in animals is miltefosine. Thus, the search for innovative drugs is necessary, some of which are already in phases of laboratory trials and others have been indicated for use in clinical routine in other countries. Therefore, the objective of the present study was to highlight the therapeutic possibilities against CVL, trying to emphasize, mainly, the new drugs frequently used in clinical routine, as well as those that have the potential to become viable options for the approach of CVL in Brazil. For the review, we implemented a manual systematic search in the main scientific databases, using indexers related to the theme in the period from 1994 to 2022. The results of the systematic search revealed that the therapeutic options potentially active against Leishmania infantum include marbofloxacin, beta-glucans, immunomodulators, and essential oils from medicinal plants and their derivative compounds, which are considered promising candidates for the treatment and control of CVL. Therefore, from the data gathered, it was possible to verify that there are many studies about the therapeutics of the disease and that understanding them can be decisive in providing good care to the sick animal, as well as in the implementation of an adequate drug planning. La leishmaniosis visceral canina (LVC) es considerada una enfermedad endémica en varias regiones de Brasil, siendo el foco de varias políticas públicas debido a su potencial zoonótico. El único medicamento regulado por el Ministerio de Agricultura, Ganadería y Abastecimiento (MAPA) en el país para el tratamiento de la enfermedad en los animales es la miltefosina. Por ello, es necesaria la búsqueda de fármacos innovadores, algunos de los cuales ya se encuentran en fase de ensayos de laboratorio y otros han sido indicados para su uso en la rutina clínica en otros países. Por lo tanto, el objetivo del presente estudio fue destacar las posibilidades terapéuticas contra la CVL, tratando de enfatizar, principalmente, los nuevos fármacos frecuentemente utilizados en la rutina clínica, así como aquellos que tienen el potencial de convertirse en opciones viables para el abordaje de la CVL en Brasil. Para la revisión, se implementó una búsqueda sistemática manual en las principales bases de datos científicas, utilizando indizadores relacionados con el tema en el período comprendido entre 1994 y 2022. Los resultados de la búsqueda sistemática revelaron que las opciones terapéuticas potencialmente activas contra Leishmania infantum incluyen la marbofloxacina, los betaglucanos, los inmunomoduladores, así como los aceites esenciales de plantas medicinales y sus compuestos derivados, que se consideran candidatos prometedores para el tratamiento y el control de la CVL. Por lo tanto, a partir de los datos recogidos, se pudo comprobar que existen muchos estudios sobre la terapéutica de la enfermedad y que su comprensión puede ser decisiva para proporcionar una buena atención al animal enfermo, así como para la aplicación de un plan farmacológico adecuado. A Leishmaniose Visceral Canina (LVC) é considerada uma enfermidade endêmica em diversas regiões do Brasil, sendo foco de diversas políticas públicas em virtude de seu potencial zoonótico. A única medicação regulamentada pelo Ministério de Agricultura, Pecuária e Abastecimento (MAPA) no país, para o tratamento da enfermidade em animais, é a miltefosina. Desta forma, a busca por fármacos inovadores é necessária, os quais alguns já se encontram em fases de ensaios laboratoriais e outros têm sido indicados para uso na rotina clínica em outros países. Assim sendo, o objetivo do presente trabalho foi evidenciar as possibilidades terapêuticas contra a LVC, buscando ressaltar, principalmente, os novos fármacos frequentemente utilizados na rotina clínica, bem como aqueles que possuem potencial para se tornarem opções viáveis para a abordagem da LVC no Brasil. Para a revisão, implementou-se uma busca sistemática manual nas principais bases de dados científicos, a partir da utilização de indexadores relacionados à temática no período de 1994 a 2022. Os resultados da busca sistemática revelaram que as opções terapêuticas potencialmente atuantes contra Leishmania infantum incluem marbofloxacina, beta-glucanas, imunomoduladores, além de óleos essenciais de plantas medicinais e seus compostos derivativos, sendo esses considerados candidatos promissores para o tratamento e controle da LVC. Portanto, a partir dos dados reunidos, foi possível verificar que existem muitos estudos acerca da terapêutica da enfermidade e, que o entendimento pode ser decisivo no fornecimento de um bom atendimento ao animal doente, bem como na implementação de um planejamento medicamentoso adequado.

Published
2022

28. Leishmaniasis visceral en el sur de Brasil: análisis critic frente a la evolución epidemiológica

Author

Dias, Tábata Pereira, Versteg, Nielle, Jardim, Gabriela de Carvalho, Borges, Laura Vieira, Leal, Karine Bastos, Gressler, Renata Pierobom, Figueiredo, Fabiano Borges, and Cleff, Marlete Brum

Subjects
Inquérito Epidemiológico, Doenças tropicais negligenciadas, Enfermedades tropicales desatendidas, Neglected tropical diseases, Leishmania Infantum, Epidemiologic survey, Encuesta epidemiológica
Abstract

Visceral leishmaniasis (VL) was considered non-endemic in the southern region of the country until 2006 when there was the first notification of na autochthonous canine case in the municipality of São Borja in Rio Grande do Sul. The states of Santa Catarina and Paraná the autochthony in canines occurred in the years 2010 and 2012 respectively. In the southern region, dueto its recent installation in addition to the few notifications, there is a lack of inclusion of the disease in differential diagnoses in human and veterinary clinics being the prevalence of VL is greater than the record on notified cases.Thus, the objective was to review the situation of human and canine VL and the presence of vectors in the southern region of the country. Official publications on the disease between 2009 and 2020 were considered and online journal data bases were consulted. Conflicting in formation was found regarding the number of cases and location of the infection, which maybe a consequence of the change in the standardization of human VL records, decentralization and lack of uniformity in CVL records, in addition to the dissemination of diagnoses through out dated annual epidemiological bulletins The sandfly Lutzomyia gaminarai, an endemic species in southern Brazil, requires attention from surveillance and researchers dueto its phylogenetic proximity to Lutzomyia longipalpis. La leishmaniasis visceral (LV) fue considerada indemne en la región sur del país hasta 2006, cuando hubo la primera notificación de un caso canino autóctono en el municipio de São Borja, Rio Grande do Sul. En los estados de Santa Catarina y Paraná, la autoctonía en caninos ocurrió en 2010 y 2012 respectivamente. En la región sur, como fue instalada recientemente, además de las pocas notificaciones, hay falta de inclusión de la enfermedad en los diagnósticos diferenciales en la clínica humana y veterinaria, con prevalencia de LV superior al registro de casos notificados. Así, el objetivo fue revisar la situación de la LV humana y canina (LVC) y la presencia de vectores en la región sur del país. Se consideraron las publicaciones oficiales sobre la enfermedad entre 2009 y 2020 y se consultaron las bases de datos de revistas en línea. Se encontró información contradictoria en cuanto al número de casos y localización de la infección, lo que puede ser consecuencia del cambio en la estandarización de los registros de LV em humanos, la descentralización y falta de uniformidad en los registros de LVC, además de la difusión de diagnósticos a través de boletines epidemiológicos anuales desactualizados. La mosca de la arena Lutzomyia gaminarai, una especie endémica del sur de Brasil, requiere la atención de la vigilancia y los investigadores, debido a su proximidad filogenética a Lutzomyia longipalpis. A leishmaniose visceral (LV) foi considerada indene na região sul do país até 2006, quando houve a primeira notificação de caso autóctone canino no município de São Borja no Rio Grande do Sul. Nos estados de Santa Catarina e Paraná, a autoctonia em caninos ocorreu nos anos 2010 e 2012 respectivamente. Na região sul, por ser de instalação recente, além das poucas notificações, observa-se a falta da inclusão da enfermidade nos diagnósticos diferenciais na clínica humana e veterinária, sendo a prevalência da LV maior que o registro de casos notificados. Assim, objetivou-se revisar a situação da LV humana e canina (LVC) e a presença dos vetores na região sul do país. Foram consideradas publicações oficiais sobre a doença entre 2009 e 2020 e consultadas as bases de periódicos online. Foram encontradas informações conflitantes quanto ao número de casos e localidade da infecção, que podem ser consequência da mudança na padronização dos registros de LV humana, da descentralização e falta de uniformidade nos registros de LVC, além da divulgação dos diagnósticos através de boletins epidemiológicos anuais desatualizados. Requer atenção da vigilância e dos pesquisadores o flebotomíneo Lutzomyia gaminarai, espécie endêmica no sul do Brasil, pela proximidade filogenética com a Lutzomyia longipalpis.

Published
2022

32. One Health approach on human seroprevalence of anti-Toxocara antibodies, Toxocara spp. eggs in dogs and sand samples between seashore mainland and island areas of southern Brazil

Author

Delai, Ruana Renostro, primary, Freitas, Aaronson Ramathan, additional, Kmetiuk, Louise Bach, additional, Merigueti, Yslla Fernanda Fitz Balo, additional, Ferreira, Isabella Braghin, additional, Lescano, Susana Angélica Zevallos, additional, Gonzáles, William Henry Roldan, additional, Brandão, Ana Pérola Drulla, additional, de Barros-Filho, Ivan Roque, additional, Pettan-Brewer, Christina, additional, Figueiredo, Fabiano Borges, additional, dos Santos, Andrea Pires, additional, Pimpão, Cláudia Turra, additional, Santarém, Vamilton Alvares, additional, and Biondo, Alexander Welker, additional

Published
2021
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35. Frequency of co-seropositivities for certain pathogens and their relationship with clinical and histopathological changes and parasite load in dogs infected with Leishmania infantum

Author

Oliveira, Valéria da Costa, primary, Junior, Artur Augusto Velho Mendes, additional, Ferreira, Luiz Claudio, additional, Calvet, Tatiana Machado Quinates, additional, dos Santos, Shanna Araujo, additional, Figueiredo, Fabiano Borges, additional, Campos, Monique Paiva, additional, Rodrigues, Francisco das Chagas de Carvalho, additional, de Oliveira, Raquel de Vasconcellos Carvalhaes, additional, de Lemos, Elba Regina Sampaio, additional, Rozental, Tatiana, additional, da Silva, Raphael Gomes, additional, Amendoeira, Maria Regina Reis, additional, Teles-de-Freitas, Rayane, additional, Bruno, Rafaela Vieira, additional, Morgado, Fernanda Nazaré, additional, Miranda, Luciana de Freitas Campos, additional, and Menezes, Rodrigo Caldas, additional

Published
2021
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37. Phase II validation study of the rK39 ELISA prototype for the diagnosis of canine visceral leishmaniasis in Brazil

Author

Medeiros, Fernanda Alvarenga Cardoso, primary, Souza Filho, Job Alves de, additional, Barbosa, José Ronaldo, additional, Donato, Lucas Edel, additional, Figueiredo, Fabiano Borges, additional, Werneck, Guilherme Loureiro, additional, Paz, Gustavo Fontes, additional, Thompson, Mayerson, additional, and Marcelino, Andreza Pain, additional

Published
2021
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42. Frequency, active infection and load of Leishmania infantum and associated histological alterations in the genital tract of male and female dogs

Author

Boechat, Viviane Cardoso, primary, Pereira, Sandro Antonio, additional, Júnior, Artur Augusto Velho Mendes, additional, dos Santos, Shanna Araujo, additional, Miranda, Luciana de Freitas Campos, additional, Figueiredo, Fabiano Borges, additional, Ferreira, Luiz Claudio, additional, de Carvalho Rodrigues, Francisco das Chagas, additional, de Oliveira, Raquel de Vasconcellos Carvalhaes, additional, -de-Freitas, Rayane Teles, additional, Bruno, Rafaela Vieira, additional, Morgado, Fernanda Nazaré, additional, and Menezes, Rodrigo Caldas, additional

Published
2020
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43. ‘ Candidatus Mycoplasma haemoalbiventris’, a novel hemoplasma species in white‐eared opossums ( Didelphis albiventris ) from Brazil

Author

Pontarolo, Giane Helenita, primary, Kühl, Luís Felipe, additional, Pedrassani, Daniela, additional, Campos, Monique, additional, Figueiredo, Fabiano Borges, additional, Valente, Jessica Damiana Marinho, additional, Gonçalves, Luiz Ricardo, additional, André, Marcos Rogério, additional, Vieira, Thállitha Samih Wischral Jayme, additional, Vieira, Rafael Felipe da Costa, additional, and Roque de Barros Filho, Ivan, additional

Published
2020
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44. First description of parasite load and clinicopathological and anatomopathological changes in a dog naturally coinfected with Dioctophyme renale and Leishmania infantum in Brazil

Author

Oliveira, Valéria da Costa, primary, Mendes Junior, Artur Augusto Velho, additional, Cavalcanti, Maíra Cruz de Holanda, additional, Madeira, Maria de Fátima, additional, Ferreira, Luiz Cláudio, additional, Figueiredo, Fabiano Borges, additional, Campos, Monique Paiva de, additional, Nadal, Niara Vanat, additional, Almosny, Nádia Regina Pereira, additional, and Menezes, Rodrigo Caldas, additional

Published
2019
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46. Correction: Frequency of co-seropositivities for certain pathogens and their relationship with clinical and histopathological changes and parasite load in dogs infected with Leishmania infantum.

Author

Oliveira, Vale´ria da Costa, Junior, Artur Augusto Velho Mendes, Ferreira, Luiz Claudio, Calvet, Tatiana Machado Quinates, Santos, Shanna Araujo dos, Figueiredo, Fabiano Borges, Campos, Monique Paiva, Rodrigues, Francisco das Chagas de Carvalho, Oliveira, Raquel de Vasconcellos Carvalhaes de, Lemos, Elba Regina Sampaio de, Rozental, Tatiana, Silva, Raphael Gomes da, Amendoeira, Maria Regina Reis, Teles-de-Freitas, Rayane, Bruno, Rafaela Vieira, Morgado, Fernanda Nazare, Miranda, Luciana de Freitas Campos, and Menezes, Rodrigo Caldas

Subjects
LEISHMANIA infantum, DOG parasites, HISTOPATHOLOGY, MAMMARY glands, SPELLING errors, PATHOGENIC microorganisms
Abstract

This document is a correction notice for an article titled "Frequency of co-seropositivities for certain pathogens and their relationship with clinical and histopathological changes and parasite load in dogs infected with Leishmania infantum." The correction addresses an error in the spelling of the fourth author's name and an error in Table 2, where the histological change in the sample "Mammary gland" should be "Non-granulomatous mastitis" instead of "Non-granulomatous endocarditis." The correct citation for the article is provided, along with the correct information for Table 2. The document also includes copyright information and a reference to the original article. [Extracted from the article]

Published
2023
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49. Circulation of spotted fever group rickettsiae among dogs seropositive for Leishmania spp. in an urban area of Brazil

Author

Campos, Sabrina Destri Emmerick, primary, Nadal, Niara Vanat, additional, Toma, Helena Keiko, additional, Almeida, Adilson Benedito de, additional, Cordeiro, Matheus Dias, additional, Fonseca, Adivaldo Henrique da, additional, Figueiredo, Fabiano Borges, additional, Verícimo, Maurício Afonso, additional, Cunha, Nathalie Costa da, additional, and Almosny, Nádia Regina Pereira, additional

Published
2019
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