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6. Effects of a Novel High-Quality Protein Infant Formula on Energetic Efficiency and Tolerance: A Randomized Trial

Author

Kuehn, Devon, Zeisel, Steven H, Orenstein, Diana F, German, J Bruce, Field, Catherine J, Teerdhala, Shiva, Knezevic, Andrea, Patil, Sujata, Donovan, Sharon M, and Lönnerdal, Bo

Subjects
Digestive Diseases, Pediatric, Clinical Trials and Supportive Activities, Clinical Research, Prevention, Nutrition, Metabolic and endocrine, Oral and gastrointestinal, Child, Humans, Infant, Infant Formula, Lactalbumin, Lactoferrin, Milk, Human, Pediatric Obesity, Tryptophan, alpha-lactalbumin, growth, nutrition, tryptophan, Medical and Health Sciences, Gastroenterology & Hepatology
Abstract

ObjectivesProtein overfeeding in infants can have negative effects, such as diabetes and childhood obesity; key to reducing protein intake from formula is improving protein quality. The impact of a new infant formula [study formula (SF)] containing alpha-lactalbumin, lactoferrin, partially hydrolyzed whey, and whole milk on growth and tolerance compared to a commercial formula (CF) and a human milk reference arm was evaluated.MethodsThis randomized, double-blind trial included healthy, singleton, term infants, enrollment age ≤14 days. Primary outcome was mean daily weight gain. Secondary outcomes were anthropometrics, formula intake, serum amino acids, adverse events, gastrointestinal characteristics, and general disposition.ResultsNon-inferiority was demonstrated. There were no differences between the formula groups for z scores over time. Formula intake [-0.33 oz/kg/day, 95% confidence interval (CI): -0.66 to -0.01, P = 0.05] and mean protein intake (-0.13 g/kg/day, 95% CI: -0.26 to 0.00, P = 0.05) were lower in the SF infants, with higher serum essential amino acid concentrations (including tryptophan) compared to the CF infants. Energetic efficiency was 14.0% (95% CI: 8.3%, 19.7%), 13.0% (95% CI: 6.0%, 20.0%), and 18.1% (95% CI: 9.4%, 26.8%) higher for weight, length, and head circumference, respectively, in SF infants compared to the CF infants. SF infants had significantly fewer spit-ups and softer stool consistency than CF infants.ConclusionsThe SF resulted in improved parent-reported gastrointestinal tolerance and more efficient growth with less daily formula and protein intake supporting that this novel formula may potentially reduce the metabolic burden of protein overfeeding associated with infant formula.

Published
2022

10. Maternal pre-pregnancy BMI influences the associations between bisphenol and phthalate exposures and maternal weight changes and fat accumulation

Author

Kaplan, B.J., Field, C.J., Bell, R.C., Bernier, F.P., Cantell, M., Casey, L.M., Eliasziw, M., Farmer, A., Gagnon, L., Giesbrecht, G.F., Goonewardene, L., Johnston, D., Kooistra, L., Letourneau, N., Manca, D.P., Martin, J.W., McCargar, L.J., O'Beirne, M., Pop, V.J., Deane, A.J., Singhal, N., Letourneau (current Pi), N., Dewey, D., Forbes, L., Giesbrecht, G., Lebel, C., Leung, B., McMorris, C., Ross, K., Irvine, Nathalie, Bell, Rhonda C., Subhan, Fatheema B., Field, Catherine J., Liu, Jiaying, MacDonald, Amy M., Kinniburgh, David W., Martin, Jonathan W., Dewey, Deborah, and England-Mason, Gillian

Published
2024
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11. Psychosocial Interventions for Alcohol Use Among Problem Drug Users: Protocol for a Feasibility Study in Primary Care

Author

Klimas, Jan, Anderson, Rolande, Bourke, Margaret, Bury, Gerard, Field, Catherine Anne, Kaner, Eileen, Keane, Rory, Keenan, Eamon, Meagher, David, Murphy, Brian, O'Gorman, Clodagh SM, O'Toole, Thomas P, Saunders, Jean, Smyth, Bobby P, Dunne, Colum, and Cullen, Walter

Subjects
Medicine, Computer applications to medicine. Medical informatics, R858-859.7
Abstract

BackgroundAlcohol use is an important issue among problem drug users. Although screening and brief intervention (SBI) are effective in reducing problem alcohol use in primary care, no research has examined this issue among problem drug users. ObjectiveThe objective of this study is to determine if a complex intervention including SBI for problem alcohol use among problem drug users is feasible and acceptable in practice. This study also aims to evaluate the effectiveness of the intervention in reducing the proportion of patients with problem alcohol use. MethodsPsychosocial intervention for alcohol use among problem drug users (PINTA) is a pilot feasibility study of a complex intervention comprising SBI for problem alcohol use among problem drug users with cluster randomization at the level of general practice, integrated qualitative process evaluation, and involving general practices in two socioeconomically deprived regions. Practices (N=16) will be eligible to participate if they are registered to prescribe methadone and/or at least 10 patients of the practice are currently receiving addiction treatment. Patient must meet the following inclusion criteria to participate in this study: 18 years of age or older, receiving addiction treatment/care (eg, methadone), or known to be a problem drug user. This study is based on a complex intervention supporting SBI for problem alcohol use among problem drug users (experimental group) compared to an “assessment-only” control group. Control practices will be provided with a delayed intervention after follow-up. Primary outcomes of the study are feasibility and acceptability of the intervention to patients and practitioners. Secondary outcome includes the effectiveness of the intervention on care process (documented rates of SBI) and outcome (proportion of patients with problem alcohol use at the follow-up). A stratified random sampling method will be used to select general practices based on the level of training for providing addiction-related care and geographical area. In this study, general practitioners and practice staff, researchers, and trainers will not be blinded to treatment, but patients and remote randomizers will be unaware of the treatment. ResultsThis study is ongoing and a protocol system is being developed for the study. This study may inform future research among the high-risk population of problem drug users by providing initial indications as to whether psychosocial interventions for problem alcohol use are feasible, acceptable, and also effective among problem drug users attending primary care. ConclusionsThis is the first study to examine the feasibility and acceptability of complex intervention in primary care to enhance alcohol SBI among problem drug users. Results of this study will inform future research among this high-risk population and guide policy and service development locally and internationally.

Published
2013
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39. Exposure

Author

Field, Catherine

Subjects
Library and information science, Publishing industry
Abstract

Emerson, Ramona. Exposure. Soho Crime. (A Rita Todacheene Novel, Bk. 2). Oct. 2024. 288p. ISBN 9781641294768. $29.95. M Photographer and crime scene specialist Rita Todacheene is back at work after [...]

Published
2024

41. science & technology

Author

Peterson, Kelsy, Tansley, Sarah, Hoover, Danise, Gardiner, P.J., DeWild, Melissa, Field, Catherine, Wyatt, Neal, Charles, John, Dixon, Steve, Moore, Jennifer, Toftness, Naomi, Pugl, Dave, Cooper, Elissa, and Lee-Smith, Wade

Subjects
Five Marys Family Style: Recipes and Traditions from the Ranch (Nonfiction work) -- Heffernan, Mary -- Thomson, Jess, Seeing Science: The Art of Making the Invisible Visible (Nonfiction work) -- Challoner, Jack, Smitten Kitchen Keepers: New Classics for Your Forever Files (Nonfiction work) -- Perelman, Deb, Back to the Moon: The Next Giant Leap for Humankind (Nonfiction work) -- Silk, Joseph, Nadiya's Everyday Baking: From Weeknight Dinners to Celebration Cakes, Let Your Oven Do the Work (Nonfiction work) -- Hussain, Nadiya, Enebla: Recipes from an Ethiopian Kitchen (Nonfiction work) -- Moges, Luladey, Very Good Salads: Middle-Eastern Salads and Plates for Sharing (Nonfiction work) -- Allan, Louisa -- Rosenboim, Shuki, The Rescue Effect: The Key to Saving Life on Earth (Nonfiction work) -- Webster, Michael Mehta, The Vegan Chinese Kitchen: Recipes and Modern Stories from a Thousand-Year-Old Tradition (Nonfiction work) -- Che, Hannah, Home Is Where the Eggs Are (Nonfiction work) -- Yeh, Molly, The Battle Cry of the Siamese Kitten: Even More Tales from the Accidental Veterinarian (Nonfiction work) -- Schott, Philipp, Time to Think Small: How Nimble Environmental Technologies Can Solve the Planet's Biggest Problems (Nonfiction work) -- Myers, Todd, Prep And Rally: An Hour of Prep, a Week of Delicious Meals (Nonfiction work) -- Klein, Dini, Northern Soul: Southern-Inspired Home Cooking from a Northern Kitchen (Nonfiction work) -- Sutherland, Justin, Everyday Cake: 45 Simple Recipes for Layer, Bundt, Loaf, and Sheet Cakes (Nonfiction work) -- Chesnakova, Polina, Soup Broth Bread: 120 Vibrant and Heartwarming Recipes (Nonfiction work) -- Allen, Rachel, Darwin's Love of Life: A Singular Case of Biophilia (Nonfiction work) -- Harel, Kay, BUDMO! Recipes from a Ukrainian Kitchen (Nonfiction work) -- Voloshyna, Anna, Books -- Book reviews, Library and information science
Abstract

HOME ECONOMICS Allan, Louisa & Shuki Rosenboim. Very Good Salads: Middle-Eastern Salads and Plates for Sharing. Smith Street. Oct. 2022.192p. ISBN 9781922417862. COOKING Since 2016, Allan and Rosenheim's wildly popular [...]

Published
2022

43. Elucidating the role of the gut microbiota in the physiological effects of dietary fiber

Author

Deehan, Edward C., Zhang, Zhengxiao, Riva, Alessandra, Armet, Anissa M., Perez-Muñoz, Maria Elisa, Nguyen, Nguyen K., Krysa, Jacqueline A., Seethaler, Benjamin, Zhao, Yuan-Yuan, Cole, Janis, Li, Fuyong, Hausmann, Bela, Spittler, Andreas, Nazare, Julie-Anne, Delzenne, Nathalie M., Curtis, Jonathan M., Wismer, Wendy V., Proctor, Spencer D., Bakal, Jeffrey A., Bischoff, Stephan C., Knights, Dan, Field, Catherine J., Berry, David, Prado, Carla M., and Walter, Jens

Published
2022
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44. LEAF HAIR TUFTS FUNCTION AS DOMATIA FOR MITES IN QUERCUS AGRIFOLIA (FAGACEAE)

Author

Coltharp, Erin, Knowd, Chloe, Abelli-Amen, Ella, Abounayan, Andrew, Alcaraz, Sophia, Auer, Rachael, Beilman, Sarah, Breit, Emma, Brennan, Jillian, Brown, Hannah, Cancroft, Owen, Carlson, James M, Carpenter, Melissa, Carreiro, Nalana, Couser, Rhys, Diaz, Stephanie, Gonzalez, Shannon Nadine Erpenbach, Field, Catherine, Fields, Lindsay, Fowler, Myles, Goldston, Brittany, Griego, Ella, Hale, Desiree, Hunter, Rachel, Inman, Jared, Krumins, Benjamin, Mattern, Evan, Mccollum, Maxwell, Mcneill, Erik, Miller, Katie, Mistry, Marshall, Plastina, Gabrielle, Rarig, Keelan, Roge, Adam, Selfridge, Hannah, Staats, Theodore, Tran, Emily, Trinh, Benjamin, Waitkus, Sonja, Walsh, Peter, Weiss, Adam, Willcox, Alexander, Young, Oliver, Zervas, James, Grossenbacher, Dena, and Weber, Marjorie

Published
2020

46. Maternal smoking during pregnancy increases the risk of gut microbiome-associated childhood overweight and obesity

Author

Peng, Ye, primary, Tun, Hein M, additional, Ng, Siew C, additional, Wai, Hogan Kok-Fung, additional, Zhang, Xi, additional, Parks, Jaclyn, additional, Field, Catherine J, additional, Mandhane, Piush, additional, Moraes, Theo J, additional, Simons, Elinor, additional, Turvey, Stuart E, additional, Subbarao, Padmaja, additional, Brook, Jeffrey R, additional, Takaro, Tim K, additional, Scott, James A, additional, Chan, Francis KL, additional, and Kozyrskyj, Anita L, additional

Published
2024
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48. The metabolic load‐capacity model and cardiometabolic health in children and youth with obesity

Author

Orsso, Camila E., primary, Vieira, Flavio T., additional, Basuray, Nandini, additional, Duke, Reena L., additional, Pakseresht, Mohammadreza, additional, Rubin, Daniela A., additional, Ajamian, Faria, additional, Ball, Geoff D. C., additional, Field, Catherine J., additional, Heymsfield, Steven B., additional, Siervo, Mario, additional, Prado, Carla M., additional, and Haqq, Andrea M., additional

Published
2024
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