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The paper presents the results of the analysis of demographic and medico-social data characterizing the dynamics of morbidity and mortality from environmental diseases, in particular, diseases of the cardiovascular system. The trend of negative natural population growth was revealed, amounting to -6.9 per 1,000 persons by 2019. The number of patients with cardiovascular diseases was 13 817,4 persons, with the overwhelming majority of the working-age population (9020,2 persons). Ischemic heart disease had the largest share in the structure of the studied diseases (62,25 %). There was also a decrease in life expectancy over the past 30 years and an increase in mortality of young and middle-aged people.