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4 results on '"Festus Adzaku"'

1. Presentations of sickle cell disease patients to hospital in Ghana: key findings from a preliminary study at Volta Regional Hospital

Author

Augustine K. Y. Oduro, Paul Telfer, Amelia E. Fisher, and Festus Adzaku

Subjects
Male, Pediatrics, medicine.medical_specialty, 030231 tropical medicine, Cell, Anemia, Sickle Cell, Comorbidity, Disease, Ghana, Miscarriage, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, Acute Chest Syndrome, parasitic diseases, medicine, Humans, 030212 general & internal medicine, Ulcer, Red blood cell disorders, business.industry, Hematology, medicine.disease, Abortion, Spontaneous, Hospitalization, Regional hospital, Phenotype, medicine.anatomical_structure, Female, Symptom Assessment, business, human activities, Biomarkers, Malaria
Abstract

Keywords: haemoglobinopathies; malaria; miscarriage; red blood cell disorders; sickle cell disease

Published
2016
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2. Carpal tunnel syndrome in haemodialysis patients: early detection by electroneurophysiological studies

Author

Mohammed A. Al-Homrany, M. G. Harding, M. R. H. Khan, and Festus Adzaku

Subjects
medicine.medical_specialty, medicine.diagnostic_test, business.industry, Decompression, medicine.medical_treatment, Physical examination, General Medicine, Electromyography, medicine.disease, Median nerve, nervous system diseases, Surgery, medicine.anatomical_structure, Nephrology, Anesthesia, medicine, Carpal tunnel, medicine.symptom, business, Carpal tunnel syndrome, Wasting, Dialysis
Abstract

SUMMARY: Carpal tunnel syndrome (CTS) is the most common nerve entrapment disorder. It is characterized by pain, paraesthesia and, ultimately, muscle wasting of the hand. The purpose of this study was to evaluate the prevalence of CTS among haemodialysis patients both clinically and with the use of electromyography (EMG). Fifty-five dialysis patients on regular haemodialysis treatment were included. There were 34 (62%) female and 21 (38%) male patients. The mean age was 47.3 ± 13.7 years. The mean age at commencement of dialysis was 44.4 ± 14.5 years. The mean duration on dialysis was 37 months. Twenty-two patients (40.8%) showed normal examination and normal EMG findings. Thirty-two patients (59.2%) had either abnormal EMG findings or positive physical signs or both. Further analysis of these 32 patients indicated that 13 patients (24%) had abnormal EMG finding compatible with the diagnosis of CTS and there were abnormal clinical features in 26 patients (48%) (seven patients with positive EMG findings and 19 patients with negative EMG studies). There was not a good correlation between EMG and the clinical examination. There was a statistically significant positive correlation between the finding of abnormal EMG suggesting CTS and the duration on dialysis, with increasing prevalence observed in patients treated for more than 5 years (P = 0.039). CTS was also diagnosed by EMG in 18% of patients remaining on dialysis for less than 5 years. This study revealed the high prevalence of CTS in dialysis patients and emphasizes the importance of EMG studies in the detection of early cases of CTS. It also provides quantitative data for timely surgical intervention before irreversible changes and during the follow-up of patients after decompression of the median nerve.

Published
2001
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3. Asymptomatic Plasmodium falciparum infection and poor school performance in primary school children in the Volta Region of Ghana.

Author

Verner, Orish, Kokou, Amegan Aho, Jones, Ofori-Amoah, James, Osei-Yobah, Ibrahim, Jamfaru, Innocent, Afeke, Lennox, Mac-Ankrah, and Festus, Adzaku

Subjects
PLASMODIUM falciparum, PRIMARY schools, SCHOOL children, CHI-squared test, INTELLECTUAL development
Abstract

BACKGROUND: This study aimed to evaluate the association between asymptomatic Plasmodium falciparum infection and poor intellectual development in primary school children in the Volta Region of Ghana. METHODS: This was a cross-sectional study conducted among children from 5 primary schools in 3 districts in the Volta region of Ghana. Questionnaires were administered, and blood samples collected for malaria investigation using Rapid diagnostic test (RDT) and microscopy. School performance was used to assess intellectual development in the children. Arithmetic was the subject of choice for the standardized test. Pearson chi square test was used to evaluate the association between Plasmodium falciparum and poor school performance. Multivariate analysis was used to identify factors independently associated with risk of poor school performance. RESULTS: Out of 550 children, 305(55.45%) tested positive for malaria with RDT and 249(45.27%) positive with microscopy. Children from the Evangelical Presbyterian (EP) primary school in Afegame had the highest prevalence of Plasmodium falciparum infection with both RDT (92, 74.80%) and microscopy (73, 59.35%). Two hundred and fifteen students (39.09%) failed the arithmetic school test. EP primary school in Afegame recorded the highest frequency of poor school performance among the children (53.66%). School performance was significantly associated with RDT malaria diagnosis with failure rate higher among children who were RDT positive (135, 62.79%, p=0.005). Lower mean scores were seen in children with positive RDT result (47.35, [SD 30.85], p=0.021). Plasmodium falciparum infection (RDT) was independently associated with increased risk of poor school performance (AOR, 1.92, p=0.003). CONCLUSION: An urgent scale-up of malaria control program targeting school-going children in this region is needed to mitigate the possible negative impact of Plasmodium falciparum infection on their intellectual development. [ABSTRACT FROM AUTHOR]

Published
2018
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