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21 results on '"Ferrucci, Massimo"'

3. Nodal Burden and Oncologic Outcomes in Patients With Residual Isolated Tumor Cells After Neoadjuvant Chemotherapy (ypN0i+): The OPBC-05/ICARO Study

Author

Montagna, Giacomo, Laws, Alison, Ferrucci, Massimo, Mrdutt, Mary M., Sun, Susie X., Bademler, Suleyman, Balbaloglu, Hakan, Balint-Lahat, Nora, Banys-Paluchowski, Maggie, Barrio, Andrea V., Benson, John, Bese, Nuran, Boughey, Judy C., Boyle, Marissa K., Diego, Emilia J., Eden, Claire, Eller, Ruth, Goldschmidt, Maite, Hlavin, Callie, Heidinger, Martin, Jelinska, Justyna, Karadeniz Cakmak, Güldeniz, Kesmodel, Susan B., King, Tari A., Kuerer, Henry M., Loesch, Julie, Milardi, Francesco, Murawa, Dawid, Moo, Tracy-Ann, Menes, Tehillah S., Passeri, Daniele, Pastoriza, Jessica M., Perhavec, Andraz, Pislar, Nina, Polidorio, Natália, Rami, Avina, Ryu, Jai Min, Schulz, Alexandra, Sevilimedu, Varadan, Ugurlu, M. Umit, Uras, Cihan, van Hemert, Annemiek, Wong, Stephanie M., Yoo, Tae-Kyung Robyn, Zhang, Jennifer Q., Karanlik, Hasan, Cabioğlu, Neslihan, Peeters, Marie-Jeanne Vrancken, Morrow, Monica, Weber, Walter P., Ahn, Sung Gwe, Andreozzi, Mariacarla, Barbalho, Daniel Meirelles, Boileau, Jean François, Brogi, Edi, Cabero, Flavia Vidal, Cocco, Daniela, Corsi, Fabio, Crown, Angelena, de Bree, Eelco, del Mar Vernet-Tomas, Maria, Deutschmann, Christine, Ditsch, Nina, Esposito, Emanuela, Fayanju, Oluwadamilola M., Fick, Franziska, Fitzal, Florian, Flanagan, Meghan R., Gentile, Damiano, Gentilini, Oreste D., Grabenstetter, Anne, Gulcelik, Mehmet Ali, Heil, Jörg, Holtschmidt, Johannes, Krawczyk, Natalia, Kühn, Thorsten, Kümmel, Sherko, Leo, Cornelia, Muslumanoglu, Mahmut, Nekljudova, Valentina, Newman, Lisa A., Pilewskie, Melissa L., Poulakaki, Fiorita, Riedel, Fabian, Rocco, Nicola, Schnabel, Freya R., Schwartz, Christopher, Siegel, Emily L., Simonson, Colin, Singer, Christian, Soares, Leonardo Ribeiro, Christina Tampaki, Ekaterini, Tampakis, Athanasios, Tasoulis, Marios Konstantinos, Tausch, Christoph, Urban, Cicero, Van den Bruele, Astrid Botty, Vergauwen, Glenn, Vorburger, Denise, Wärnberg, Fredrik, Weiss, Anna, Williams, Austin D., Wimmer, Kerstin, Woodward, Steven G., and Ziauddin, Firdos M.

Published
2024
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7. Nodal Burden and Oncologic Outcomes in Patients With Residual Isolated Tumor Cells After Neoadjuvant Chemotherapy (ypN0i+): The OPBC-05/ICARO Study.

Author

Montagna, Giacomo, Laws, Alison, Ferrucci, Massimo, Mrdutt, Mary M., Sun, Susie X., Bademler, Suleyman, Balbaloglu, Hakan, Balint-Lahat, Nora, Banys-Paluchowski, Maggie, Barrio, Andrea V., Benson, John, Bese, Nuran, Boughey, Judy C., Boyle, Marissa K., Diego, Emilia J., Eden, Claire, Eller, Ruth, Goldschmidt, Maite, Hlavin, Callie, and Heidinger, Martin

Published
2025
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11. Exosomes as novel prognostic biomarker in potentially resectable colorectal cancer liver metastatic (CCLM) patients.

Author

Zurlo, Ina Valeria, primary, Di Salvatore, Mariantonietta, additional, Lucchetti, Donatella, additional, Colella, Filomena, additional, Ricciardi Tenore, Claudio, additional, Perelli, Luigi, additional, Ferrucci, Massimo, additional, Basso, Michele, additional, Vellone, Maria, additional, Calegari, Maria Alessandra, additional, Salvatore, Lisa, additional, Pozzo, Carmelo, additional, Giuliante, Felice, additional, Cassano, Alessandra, additional, Sgambato, Alessandro, additional, and Tortora, Giampaolo, additional

Published
2019
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16. Penile cancer metastasizing to the breast: a case report

Author

Franceschini, Gianluca, Sanchez, Alejandro Martin, Di Leone, Alba, Scaldaferri, Assunta, Ferrucci, Massimo, Mulè, Antonio, Costantini, Melania, Masetti, Riccardo, Franceschini, Gianluca (ORCID:0000-0002-2950-3395), Masetti, Riccardo (ORCID:0000-0002-7520-9111), Franceschini, Gianluca, Sanchez, Alejandro Martin, Di Leone, Alba, Scaldaferri, Assunta, Ferrucci, Massimo, Mulè, Antonio, Costantini, Melania, Masetti, Riccardo, Franceschini, Gianluca (ORCID:0000-0002-2950-3395), and Masetti, Riccardo (ORCID:0000-0002-7520-9111)

Abstract

BACKGROUND: Penile cancer is a relatively uncommon cancer in developed nations. Metastatic disease is rare, but lymphatic or vascular spreading has been previously reported to the liver, lungs, bones, brain, heart and skin. CASE PRESENTATION: We report a case of a 49-year-old white man with a penile squamous cell carcinoma previously treated with partial penectomy and bilateral inguinal lymph node dissection, followed by adjuvant therapy. Three years after treatment, the primitive neoplasm metastasized to the breast, presenting as a painful lump. Differentials of a secondary versus a malignant primary tumor were considered and in view of a diagnostic dilemma the lesion was excised. CONCLUSIONS: This case is unusual in its site of metastatic progression as well as in its pattern of clinical presentation. Awareness of such a condition by physicians is mandatory in order to make an early diagnosis and start prompt and correct therapeutic planning.

Published
2016

17. Penile cancer metastasizing to the breast: a case report

Author

Franceschini, Gianluca, primary, Sanchez, Alejandro Martin, additional, Di Leone, Alba, additional, Scaldaferri, Assunta, additional, Ferrucci, Massimo, additional, Mulè, Antonio, additional, Costantini, Melania, additional, and Masetti, Riccardo, additional

Published
2016
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18. Improvement in perioperative and long-term outcome after surgical treatment of hilar cholangiocarcinoma: results of an Italian multicenter analysis of 440 patients

Author

Nuzzo, Gennaro, Giuliante, Felice, Ardito, Francesco, Giovannini, Ivo, Aldrighetti, Luca, Belli, Giulio, Bresadola, Fabrizio, Calise, Fulvio, Dalla Valle, Raffaele, D'Amico, Davide F, Gennari, Leandro, Giulini, Stefano M, Guglielmi, Alfredo, Jovine, Elio, Pellicci, Riccardo, Pernthaler, Heinrich, Pinna, Antonio D, Puleo, Stefano, Torzilli, Guido, Capussotti, Lorenzo, Cillo, Umberto, Ercolani, Giorgio, Ferrucci, Massimo, Mastrangelo, Laura, Portolani, Nazario, Pulitano', Carlo, Ribero, Dario, Ruzzenente, Andrea, Scuderi, Vincenzo, Federico, Bruno, Giuliante, Felice (ORCID:0000-0001-9517-8220), Ardito, Francesco (ORCID:0000-0003-1596-2862), Nuzzo, Gennaro, Giuliante, Felice, Ardito, Francesco, Giovannini, Ivo, Aldrighetti, Luca, Belli, Giulio, Bresadola, Fabrizio, Calise, Fulvio, Dalla Valle, Raffaele, D'Amico, Davide F, Gennari, Leandro, Giulini, Stefano M, Guglielmi, Alfredo, Jovine, Elio, Pellicci, Riccardo, Pernthaler, Heinrich, Pinna, Antonio D, Puleo, Stefano, Torzilli, Guido, Capussotti, Lorenzo, Cillo, Umberto, Ercolani, Giorgio, Ferrucci, Massimo, Mastrangelo, Laura, Portolani, Nazario, Pulitano', Carlo, Ribero, Dario, Ruzzenente, Andrea, Scuderi, Vincenzo, Federico, Bruno, Giuliante, Felice (ORCID:0000-0001-9517-8220), and Ardito, Francesco (ORCID:0000-0003-1596-2862)

Abstract

OBJECTIVE: To evaluate improvements in operative and long-term results following surgery for hilar cholangiocarcinoma. DESIGN: Retrospective multicenter study including 17 Italian hepatobiliary surgery units. PATIENTS: A total of 440 patients who underwent resection for hilar cholangiocarcinoma from January 1, 1992, through December 31, 2007. MAIN OUTCOME MEASURES: Postoperative mortality, morbidity, overall survival, and disease-free survival. RESULTS: Postoperative mortality and morbidity after liver resection were 10.1% and 47.6%, respectively. At multivariate logistic regression, extent of resection (right or right extended hepatectomy) and intraoperative blood transfusion were independent predictors of postoperative mortality (P = .03 and P = .006, respectively); in patients with jaundice, mortality was also higher without preoperative biliary drainage than with biliary drainage (14.3% vs 10.7%). During the study period, there was an increasingly aggressive approach, with more frequent caudate lobectomies, vascular resections, and resections for advanced tumors (T stage of 3 or greater and tumors with poor differentiation). Despite the aggressive approach, the blood transfusion rate decreased from 81.0% to 53.2%, and mortality slightly decreased from 13.6% to 10.8%. Median overall survival significantly increased from 16 to 30 months (P = .05). At multivariate analysis, R1 resection, lymph node metastases, and T stage of 3 or greater independently predicted overall and disease-free survival. CONCLUSIONS: Surgery for hilar cholangiocarcinoma has improved with decreased operative risk despite a more aggressive surgical policy. Long-term survival after liver resection has also increased, despite the inclusion of cases with more advanced hilar cholangiocarcinoma. Preoperative biliary drainage was a safe strategy before right or right extended hepatectomy in patients with jaundice. Pathologic factors independently predicted overall and disease-free survival at multi

Published
2012

20. Improvement in perioperative and long-term outcome after surgical treatment of hilar cholangiocarcinoma: results of an Italian multicenter analysis of 440 patients

Author

Nuzzo G, Giuliante F, Ardito F, Giovannini I, Aldrighetti L, Belli G, Bresadola F, Calise F, Dalla Valle R, D'Amico DF, Gennari L, Giulini SM, Guglielmi A, Jovine E, Pellicci R, Pernthaler H, Pinna AD, Puleo S, Torzilli G, Capussotti L, Italian Chapter of the International Hepato-Pancreato-Biliary Association, Cillo U, Ercolani G, Ferrucci M, Mastrangelo L, Portolani N, Pulitanò C, Ribero D, Ruzzenente A, Scuderi V, Federico B, Nuzzo, Gennaro, Giuliante, Felice, Ardito, Francesco, Giovannini, Ivo, Aldrighetti, Luca, Belli, Giulio, Bresadola, Fabrizio, Calise, Fulvio, Dalla Valle, Raffaele, D'Amico, Davide F., Gennari, Leandro, Giulini, Stefano M., Guglielmi, Alfredo, Jovine, Elio, Pellicci, Riccardo, Pernthaler, Heinrich, Pinna, Antonio D., Puleo, Stefano, Torzilli, Guido, Capussotti, Lorenzo, Cillo, Umberto, Ercolani, Giorgio, Ferrucci, Massimo, Mastrangelo, Laura, Portolani, Nazario, Pulitanò, Carlo, Ribero, Dario, Ruzzenente, Andrea, Scuderi, Vincenzo, Federico, Bruno, Nuzzo, G, Giuliante, F, Ardito, F, Giovannini, I, Aldrighetti, L, Belli, G, Bresadola, F, Calise, F, Dalla Valle, R, D'Amico, Df, Gennari, L, Giulini, Sm, Guglielmi, A, Jovine, E, Pellicci, R, Pernthaler, H, Pinna, Ad, Puleo, S, Torzilli, G, and Capussotti, L

Subjects
Male, Blood transfusion, Time Factors, medicine.medical_treatment, Settore MED/18 - CHIRURGIA GENERALE, Adult Aged Aged, Cholangiocarcinoma, Klatskin tumor, Retrospective Studie, 80 and over, Improved results, Main biliary confluence excision, Intrahepatic Cholangiocarcinoma, Outcome, Intrahepatic, Aged, 80 and over, Liver resection, 80 and over Bile Duct Neoplasms/surgery* Bile Ducts, Intrahepatic* Cholangiocarcinoma/surgery* Female Humans Italy Male Middle Aged Retrospective Studies Time Factors Treatment Outcome, Jaundice, Middle Aged, Treatment Outcome, Italy, Female, medicine.symptom, Human, Adult, medicine.medical_specialty, Time Factor, Preoperative care, medicine, Humans, Results, Bile Duct Neoplasm, Adult, Aged, Aged, 80 and over, Bile Duct Neoplasms, surgery, Bile Ducts, Intrahepatic, Cholangiocarcinoma, surgery, Female, Humans, Italy, Male, Middle Aged, Retrospective Studies, Time Factors, Treatment Outcome, Retrospective Studies, Aged, business.industry, Retrospective cohort study, Perioperative, Hilar cholangiocarcinoma, medicine.disease, Surgery, Bile Ducts, Intrahepatic, Bile Duct Neoplasms, Bile Ducts, Hepatectomy, business
Abstract

Objective: To evaluate improvements in operative and long-term results following surgery for hilar cholangiocarcinoma. Design: Retrospective multicenter study including 17 Italian hepatobiliary surgery units. Patients: A total of 440 patients who underwent resection for hilar cholangiocarcinoma from January 1, 1992, through December 31, 2007. Main Outcome Measures: Postoperative mortality, morbidity, overall survival, and disease-free survival. Results: Postoperative mortality and morbidity after liver resection were 10.1% and 47.6%, respectively. At multivariate logistic regression, extent of resection (rightor right extended hepatectomy) and intraoperative blood transfusion were independent predictors of postoperative mortality (P =. 03 and P =. 006, respectively); in patients with jaundice, mortality was also higher without preoperative biliary drainage than with biliary drainage (14.3% vs 10.7%). During the study period, there was an increasingly aggressive approach, with more frequent caudate lobectomies, vascular resections, and resections for advanced tumors (T stage of 3 or greater and tumors with poor differentiation). Despite the aggressive approach, the blood transfusion rate decreased from 81.0% to 53.2%, and mortality slightly decreased from 13.6% to 10.8%. Median overall survival significantly increased from 16 to 30 months (P =. 05). At multivariate analysis, R1 resection, lymph node metastases, and T stage of 3 or greater independently predicted overall and disease-free survival. Conclusions: Surgery for hilar cholangiocarcinoma has improved with decreased operative risk despite a more aggressive surgical policy. Long-term survival after liver resection has also increased, despite the inclusion of cases with more advanced hilar cholangiocarcinoma. Preoperative biliary drainage was a safe strategy before right or right extended hepatectomy in patients with jaundice. Pathologic factors independently predicted overall and disease-free survival at multivariate analysis. Arch Surg. 2012; 147(1): 26-34

Published
2012
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21. Intraoperative ultrasound-guided breast-conserving surgery: A performance analysis on the basis of novel cancer lesion classification and patients' cosmetic satisfaction.

Author

Ferrucci M, Milardi F, Passeri D, Cagol M, Del Bianco P, Grossi U, and Marchet A

Abstract

Background: Intraoperative ultrasound-guided breast-conserving surgery guarantees real-time direct visualization of tumor and resection margins. We compared surgical, oncologic, and cosmetic outcomes between intraoperative ultrasound-guided breast-conserving surgery and traditional (palpation- or wire-guided) surgery across all breast cancer lesion types., Methods: This prospective observational cohort study was conducted at the Veneto Institute of Oncology between January 2021 and October 2022. Patients with ductal carcinoma in situ, T1-2 invasive breast cancer, or post-neoadjuvant residual lesions, who were suitable for breast-conserving surgery were enrolled. A novel classification system categorized all breast cancer lesion types: solid palpable (type A); solid non-palpable (B); non-solid non-palpable (C); and post-neoadjuvant residual lesions (D). Main outcomes included involved margin rates, excision volumes, and cosmetic satisfaction., Results: In total, 206 patients were enrolled, with 103 receiving traditional (palpation- or wire-guided) surgery and 103 undergoing intraoperative ultrasound-guided breast-conserving surgery. Despite similar tumor volumes, intraoperative ultrasound-guided breast-conserving surgery resulted in significantly smaller excised volumes (P = .024), greater tumor volume to specimen volume ratios (P = .002), and lower involved margin and reoperation rates (P = .002 and P = .01, respectively), in addition to a wider closest margin width (P < .001). Stratified analyses demonstrated superior performance of intraoperative ultrasound-guided breast-conserving surgery across all breast cancer lesion types, with notable improvements observed in the most challenging ones (types C and D). One-year follow-up assessments revealed significantly greater patient satisfaction levels after intraoperative ultrasound-guided breast-conserving surgery (P < .001), with specimen volume identified as the sole significant predictor of cosmetic satisfaction (P = .001)., Conclusion: Intraoperative ultrasound-guided breast-conserving surgery showed clear superiority over traditional (palpation- or wire-guided) surgery in oncologic, surgical, and cosmetic outcomes, as demonstrated by a comprehensive stratified analysis encompassing all breast cancer lesion types. Intraoperative ultrasound-guided breast-conserving surgery represents the latest and most effective paradigm for precision breast-conserving surgery., Competing Interests: Conflict of Interest/Disclosure The authors have indicated that they have no conflicts of interest regarding the content of this article., (Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.)

Published
2025
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