Author: "Ferroni V." - Searchworks@Jio Institute Digital Library Search Results

Your search keyword '"Ferroni V."' showing total 161 results

Start Over Author "Ferroni V."

161 results on '"Ferroni V."'

1. Tilt-to-length coupling in LISA Pathfinder: long-term stability

Author: Armano, M, Audley, H, Baird, J, Binetruy, P, Born, M, Bortoluzzi, D, Castelli, E, Cavalleri, A, Cesarini, A, Cruise, A M, Danzmann, K, Silva, M de Deus, Diepholz, I, Dixon, G, Dolesi, R, Ferraioli, L, Ferroni, V, Fitzsimons, E D, Freschi, M, Gesa, L, Giardini, D, Gibert, F, Giusteri, R, Grimani, C, Grzymisch, J, Harrison, I, Hartig, M-S, Heinzel, G, Hewitson, M, Hollington, D, Hoyland, D, Hueller, M, Inchauspé, H, Jennrich, O, Jetzer, P, Johann, U, Johlander, B, Karnesis, N, Kaune, B, Killow, C J, Korsakova, N, Lobo, J A, López-Zaragoza, J P, Maarschalkerweerd, R, Mance, D, Martín, V, Martin-Polo, L, Martin-Porqueras, F, Martino, J, McNamara, P W, Mendes, J, Mendes, L, Meshksar, N, Nofrarias, M, Paczkowski, S, Perreur-Lloyd, M, Petiteau, A, Plagnol, E, Ramos-Castro, J, Reiche, J, Rivas, F, Robertson, D I, Russano, G, Sanjuan, J, Slutsky, J, Sopuerta, C F, Sumner, T, Texier, D, Thorpe, J I, Vetrugno, D, Vitale, S, Wanner, G, Ward, H, Wass, P J, Weber, W J, Wissel, L, Wittchen, A, and Zweifel, P
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: The tilt-to-length coupling during the LISA Pathfinder mission has been numerically and analytically modeled for particular timespans. In this work, we investigate the long-term stability of the coupling coefficients of this noise. We show that they drifted slowly (by 1\,$\mu$m/rad and 6$\times10^{-6}$ in 100 days) and strongly correlated to temperature changes within the satellite (8\,$\mu$m/rad/K and 30$\times10^{-6}$/K). Based on analytical TTL coupling models, we attribute the temperature-driven coupling changes to rotations of the test masses and small distortions in the optical setup. Particularly, we show that LISA Pathfinder's optical baseplate was bent during the cooldown experiment, which started in late 2016 and lasted several months.
Published: 2024
Full Text: View/download PDF

2. Precision measurements of the magnetic parameters of LISA Pathfinder test masses

Author: Armano, M, Audley, H, Baird, J, Binetruy, P, Born, M, Bortoluzzi, D, Castelli, E, Cavalleri, A, Cesarini, A, Cruise, A M, Danzmann, K, Silva, M De Deus, Diepholz, I, Dixon, G, Dolesi, R, Ferraioli, L, Ferroni, V, Fitzsimons, E D, Freschi, M, Gesa, L, Giardini, D, Gibert, F, Giusteri, R, Grimani, C, Grzymisch, J, Harrison, I, Hartig, M S, Heinzel, G, Hewitson, M, Hollington, D, Hoyland, D, Hueller, M, Inchauspé, H, Jennrich, O, Jetzer, P, Karnesis, N, Kaune, B, Korsakova, N, Killow, C J, Liu, L, Lobo, J A, López-Zaragoza, J P, Maarschalkerweerd, R, Mance, D, Martín, V, Martino, J, Martin-Polo, L, Martin-Porqueras, F, McNamara, P W, Mendes, J, Mendes, L, Meshksar, N, Nofrarias, M, Paczkowski, S, Perreur-Lloyd, M, Petiteau, A, Pivato, P, Plagnol, E, Ramos-Castro, J, Reiche, J, Rivas, F, Robertson, D I, Russano, G, Serrano, D, Slutsky, J, Sopuerta, C F, Sumner, T, Texier, D, Thorpe, J I, Vetrugno, D, Vitale, S, Wanner, G, Ward, H, Wass, P, Weber, W J, Wissel, L, Wittchen, A, and Zweifel, P
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics, General Relativity and Quantum Cosmology
Abstract: A precise characterization of the magnetic properties of LISA Pathfinder free falling test-masses is of special interest for future gravitational wave observatory in space. Magnetic forces have an important impact on the instrument sensitivity in the low frequency regime below the millihertz. In this paper we report on the magnetic injection experiments performed throughout LISA Pathfinder operations. We show how these experiments allowed a high precision estimate of the instrument magnetic parameters. The remanent magnetic moment was found to have a modulus of $(0.245\pm0.081)\,\rm{nAm}^2$, the x-component of the background magnetic field within the test masses position was measured to be $(414 \pm 74)$ nT and its gradient had a value of $(-7.4\pm 2.1)\,\mu$T/m. Finally, we also measured the test mass magnetic susceptibility to be $(-3.35\pm0.15)\times$10$^{-5}$ in the low frequency regime. All results are in agreement with on-ground estimates.
Published: 2024

3. Magnetic-induced force noise in LISA Pathfinder free-falling test masses

Author: Armano, M, Audley, H, Baird, J, Binetruy, P, Born, M, Bortoluzzi, D, Castelli, E, Cavalleri, A, Cesarini, A, Cruise, A M, Danzmann, K, Silva, M De Deus, Diepholz, I, Dixon, G, Dolesi, R, Ferraioli, L, Ferroni, V, Fitzsimons, E D, Freschi, M, Gesa, L, Giardini, D, Gibert, F, Giusteri, R, Grimani, C, Grzymisch, J, Harrison, I, Hartig, M S, Heinzel, G, Hewitson, M, Hollington, D, Hoyland, D, Hueller, M, Inchauspé, H, Jennrich, O, Jetzer, P, Karnesis, N, Kaune, B, Korsakova, N, Killow, C J, Liu, L, Lobo, J A, López-Zaragoza, J P, Maarschalkerweerd, R, Mance, D, Martín, V, Martino, J, Martin-Polo, L, Martin-Porqueras, F, McNamara, P W, Mendes, J, Mendes, L, Meshksar, N, Nofrarias, M, Paczkowski, S, Perreur-Lloyd, M, Petiteau, A, Pivato, P, Plagnol, E, Ramos-Castro, J, Reiche, J, Rivas, F, Robertson, D I, Russano, G, Serrano, D, Slutsky, J, Sopuerta, C F, Sumner, T, Texier, D, Thorpe, J I, Vetrugno, D, Vitale, S, Wanner, G, Ward, H, Wass, P, Weber, W J, Wissel, L, Wittchen, A, and Zweifel, P
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics, General Relativity and Quantum Cosmology
Abstract: LISA Pathfinder was a mission designed to test key technologies required for gravitational wave detection in space. Magnetically driven forces play a key role in the instrument sensitivity in the low-frequency regime, which corresponds to the measurement band of interest for future space-borne gravitational wave observatories. Magnetic-induced forces couple to the test mass motion, introducing a contribution to the relative acceleration noise between the free falling test masses. In this Letter we present the first complete estimate of this term of the instrument performance model. Our results set the magnetic-induced acceleration noise during the February 2017 noise run of $\rm 0.25_{-0.08}^{+0.15}\,fm\,s^{-2}/\sqrt{Hz}$ at 1 mHz and $\rm 1.01_{-0.24}^{+0.73}\, fm\,s^{-2}/\sqrt{Hz}$ at 0.1 mHz. We also discuss how the non-stationarities of the interplanetary magnetic field can affect these values during extreme space weather conditions.
Published: 2024

4. In-depth analysis of LISA Pathfinder performance results: Time evolution, noise projection, physical models, and implications for LISA

Author: Armano, M., Audley, H., Baird, J., Binetruy, P., Born, M., Bortoluzzi, D., Castelli, E., Cavalleri, A., Cesarini, A., Chiavegato, V., Cruise, A. M., Bosco, D. Dal, Danzmann, K., Silva, M. De Deus, Diepholz, I., Dixon, G., Dolesi, R., Ferraioli, L., Ferroni, V., Fitzsimons, E. D., Freschi, M., Gesa, L., Giardini, D., Gibert, F., Giusteri, R., Grimani, C., Grzymisch, J., Harrison, I., Hartig, M. S., Heinzel, G., Hewitson, M., Hollington, D., Hoyland, D., Hueller, M., Inchauspé, H., Jennrich, O., Jetzer, P., Johlander, B., Karnesis, N., Kaune, B., Korsakova, N., Killow, C. J., Lobo, J. A., Lopez-Zaragoza, J. P., Maarschalkerweerd, R., Mance, D., Martın, V., Martin-Polo, L., Martin-Porqueras, F., Martino, J., McNamara, P. W., Mendes, J., Mendes, L., Meshksar, N., Nofrarias, M., Paczkowski, S., Perreur-Lloyd, M., Petiteau, A., Plagnol, E., Ramos-Castro, J., Reiche, J., Rivas, F., Robertson, D. I., Russano, G., Sala, L., Slutsky, J., Sopuerta, C. F., Sumner, T., Texier, D., Thorpe, J. I., Vetrugno, D., Vitale, S., Wanner, G., Ward, H., Wass, P., Weber, W. J., Wissel, L., Wittchen, A., Zanoni, C., and Zweifel, P.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: We present an in-depth analysis of the LISA Pathfinder differential acceleration performance over the entire course of its science operations, spanning approximately 500 days. We find that: 1) the evolution of the Brownian noise that dominates the acceleration amplitude spectral density (ASD), for frequencies $f\gtrsim 1\,\text{mHz}$, is consistent with the decaying pressure due to the outgassing of a single gaseous species. 2) between $f=36\,\mu\text{Hz}$ and $1\,\text{mHz}$, the acceleration ASD shows a $1/f$ tail in excess of the Brownian noise of almost constant amplitude, with $\simeq 20\%$ fluctuations over a period of a few days, with no particular time pattern over the course of the mission; 3) at the lowest considered frequency of $f=18\,\mu\text{Hz}$, the ASD significantly deviates from the $1/f$ behavior, because of temperature fluctuations that appear to modulate a quasi-static pressure gradient, sustained by the asymmetries of the outgassing pattern. We also present the results of a projection of the observed acceleration noise on the potential sources for which we had either a direct correlation measurement, or a quantitative estimate from dedicated experiments. These sources account for approximately $40\%$ of the noise power in the $1/f$ tail. Finally, we analyze the possible sources of the remaining unexplained fraction, and identify the possible measures that may be taken to keep those under control in LISA.
Published: 2024
Full Text: View/download PDF

5. Tilt-to-length coupling in LISA Pathfinder: a data analysis

Author: Armano, M, Audley, H, Baird, J, Binetruy, P, Born, M, Bortoluzzi, D, Castelli, E, Cavalleri, A, Cesarini, A, Cruise, A M, Danzmann, K, Silva, M de Deus, Diepholz, I, Dixon, G, Dolesi, R, Ferraioli, L, Ferroni, V, Fitzsimons, E D, Freschi, M, Gesa, L, Giardini, D, Gibert, F, Giusteri, R, Grimani, C, Grzymisch, J, Harrison, I, Hartig, M-S, Heinzel, G, Hewitson, M, Hollington, D, Hoyland, D, Hueller, M, Inchauspé, H, Jennrich, O, Jetzer, P, Johann, U, Johlander, B, Karnesis, N, Kaune, B, Killow, C J, Korsakova, N, Lobo, J A, López-Zaragoza, J P, Maarschalkerweerd, R, Mance, D, Martín, V, Martin-Polo, L, Martin-Porqueras, F, Martino, J, McNamara, P W, Mendes, J, Mendes, L, Meshksar, N, Nofrarias, M, Paczkowski, S, Perreur-Lloyd, M, Petiteau, A, Plagnol, E, Ramos-Castro, J, Reiche, J, Rivas, F, Robertson, D I, Russano, G, Sanjuan, J, Slutsky, J, Sopuerta, C F, Sumner, T, Tevlin, L, Texier, D, Thorpe, J I, Vetrugno, D, Vitale, S, Wanner, G, Ward, H, Wass, P J, Weber, W J, Wissel, L, Wittchen, A, and Zweifel, P
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: We present a study of the tilt-to-length coupling noise during the LISA Pathfinder mission and how it depended on the system's alignment. Tilt-to-length coupling noise is the unwanted coupling of angular and lateral spacecraft or test mass motion into the primary interferometric displacement readout. It was one of the major noise sources in the LISA Pathfinder mission and is likewise expected to be a primary noise source in LISA. We demonstrate here that a recently derived and published analytical model describes the dependency of the LISA Pathfinder tilt-to-length coupling noise on the alignment of the two freely falling test masses. This was verified with the data taken before and after the realignments performed in March (engineering days) and June 2016, and during a two-day experiment in February 2017 (long cross-talk experiment). The latter was performed with the explicit goal of testing the tilt-to-length coupling noise dependency on the test mass alignment. Using the analytical model, we show that all realignments performed during the mission were only partially successful and explain the reasons why. In addition to the analytical model, we computed another physical tilt-to-length coupling model via a minimising routine making use of the long cross-talk experiment data. A similar approach could prove useful for the LISA mission.
Published: 2023
Full Text: View/download PDF

6. Charging of free-falling test masses in orbit due to cosmic rays: results from LISA Pathfinder

Author: LISA Pathfinder Collaboration, Armano, M., Audley, H., Baird, J., Binetruy, P., Born, M., Bortoluzzi, D., Castelli, E., Cesarini, A. Cavalleri A., Cruise, A. M, Danzmann, K., Silva, M. de Deus, Diepholz, I., Dixon, G., Dolesi, R., Ferraioli, L., Ferroni, V., Fitzsimons, E. D., Freschi, M., Gesa, L., Giardini, D., Gibert, F., Giusteri, R., Grimani, C., Grzymisch, J., Harrison, I., Hartig, M. -S., Heinzel, G., Hewitson, M., Hollington, D., Hoyland, D., Hueller, M., Inchauspé, H., Jennrich, O., Jetzer, P., Karnesis, N., Kaune, B., Killow, C. J., Korsakova, N., Lobo, J. A., López-Zaragoza, J. P., Maarschalkerweerd, R., Mance, D., Martín, V., Martino, J., Martin-Polo, L., Martin-Porqueras, F., McNamara, P. W., Mendes, J., Mendes, L., Meshksar, N., Nofrarias, M., Paczkowski, S., Perreur-Lloyd, M., Petiteau, A., Plagnol, E., Ramos-Castro, J., Reiche, J., Rivas, F., Robertson, D. I., Russano, G., Slutsky, J., Sopuerta, C. F., Sumner, T. J., Texier, D., Thorpe, J. I., Vetrugno, D., Vitale, S., Wanner, G., Ward, H., Wass, P. J., Weber, W. J., Wissel, L., Wittchen, A., and Zweifel, P.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: A comprehensive summary of the measurements made to characterize test mass charging due to the space environment during the LISA Pathfinder mission is presented. Measurements of the residual charge of the test mass after release by the grabbing and positioning mechanism, show that the initial charge of the test masses was negative after all releases, leaving the test mass with a potential in the range $-12$ mV to $-512$ mV. Variations in the neutral test mass charging rate between $21.7$ e s$^{-1}$ and $30.7$ e s$^{-1}$ were observed over the course of the 17-month science operations produced by cosmic ray flux changes including a Forbush decrease associated with a small solar energetic particle event. A dependence of the cosmic ray charging rate on the test mass potential between $-30.2$ e s$^{-1}$ V$^{-1}$ and $-40.3$ e s$^{-1}$ V$^{-1}$ was observed and this is attributed to a contribution to charging from low-energy electrons emitted from the gold surfaces of the gravitational reference sensor. Data from the on-board particle detector show a reliable correlation with the charging rate and with other environmental monitors of the cosmic ray flux. This correlation is exploited to extrapolate test mass charging rates to a 20-year period giving useful insight into the expected range of charging rate that may be observed in the LISA mission., Comment: 17 pages, 10 figures
Published: 2022
Full Text: View/download PDF

7. Study of quantum electron diffraction for the LISA test-mass charging

Author: Villani, M., Fabi, M., Grimani, C., Sabbatini, F., Dimiccoli, F., Dolesi, R., Ferroni, V., and Weber, W.J.
Published: 2024
Full Text: View/download PDF

8. Spacecraft and interplanetary contributions to the magnetic environment on-board LISA Pathfinder

Author: Armano, M., Audley, H., Baird, J., Binetruy, P., Born, M., Bortoluzzi, D., Castelli, E., Cavalleri, A., Cesarini, A., Cruise, A. M., Danzmann, K., Silva, M. de Deus, Diepholz, I., Dixon, G., Dolesi, R., Ferraioli, L., Ferroni, V., Fitzsimons, E. D., Freschi, M., Gesa, L., Gibert, F., Giardini, D., Giusteri, R., Grimani, C., Grzymisch, J., Harrison, I., Hartig, M-S., Heinzel, G., Hewitson, M., Hollington, D., Hoyland, D., Hueller, M., Inchauspé, H., Jennrich, O., Jetzer, P., Karnesis, N., Kaune, B., Korsakova, N., Killow, C. J., Lobo, J. A., Liu, L., López-Zaragoza, J. P., Maarschalkerweerd, R., Mance, D., Martín, V., Martin-Polo, L., Martino, J., Martin-Porqueras, F., Mateos, I., McNamara, P. W., Mendes, J., Mendes, L., Meshksar, N., Nofrarias, M., Paczkowski, S., Perreur-Lloyd, M., Petiteau, A., Pivato, P., Plagnol, E., Ramos-Castro, J., Reiche, J., Rivas, F., Robertson, D. I., Roma-Dollase, D., Russano, G., Slutsky, J., Sopuerta, C. F., Sumner, T., Telloni, D., Texier, D., Thorpe, J. I., Trenkel, C., Vetrugno, D., Vitale, S., Wanner, G., Ward, H., Wass, P. J., Wealthy, D., Weber, W. J., Wissel, L., Wittchen, A., and Zweifel, P.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: LISA Pathfinder (LPF) has been a space-based mission designed to test new technologies that will be required for a gravitational wave observatory in space. Magnetically driven forces play a key role in the instrument sensitivity in the low-frequency regime (mHz and below), the measurement band of interest for a space-based observatory. The magnetic field can couple to the magnetic susceptibility and remanent magnetic moment from the test masses and disturb them from their geodesic movement. LISA Pathfinder carried on-board a dedicated magnetic measurement subsystem with noise levels of 10 $ \rm nT \ Hz^{-1/2}$ from 1 Hz down to 1 mHz. In this paper we report on the magnetic measurements throughout LISA Pathfinder operations. We characterise the magnetic environment within the spacecraft, study the time evolution of the magnetic field and its stability down to 20 $\mu$Hz, where we measure values around 200 $ \rm nT \ Hz^{-1/2}$ and identify two different frequency regimes, one related to the interplanetary magnetic field and the other to the magnetic field originating inside the spacecraft. Finally, we characterise the non-stationary component of the fluctuations of the magnetic field below the mHz and relate them to the dynamics of the solar wind., Comment: 16 pages, 17 figures. MNRAS LaTeX style file version 3.0
Published: 2020
Full Text: View/download PDF

9. LISA Pathfinder Performance Confirmed in an Open-Loop Configuration: Results from the Free-Fall Actuation Mode

Author: Armano, M., Audley, H., Baird, J., Binetruy, P., Born, M., Bortoluzzi, D., Castelli, E., Cavalleri, A., Cesarini, A., Cruise, A. M., Danzmann, K., Silva, M. de Deus, Diepholz, I., Dixon, G., Dolesi, R., Ferraioli, L., Ferroni, V., Fitzsimons, E. D., Freschi, M., Gesa, L., Gibert, F., Giardini, D., Giusteri, R., Grimani, C., Grzymisch, J., Harrison, I., Hartig, M-S., Heinzel, G., Hewitson, M., Hollington, D., Hoyland, D., Hueller, M., Inchauspé, H., Jennrich, O., Jetzer, P., Karnesis, N., Kaune, B., Korsakova, N., Killow, C. J., Lobo, J. A., Liu, L., Llopez-Zaragoza, J. P., Maarschalkerweerd, R., Mance, D., Meshksar, N., Martìn, V., Martin-Polo, L., Martino, J., Martin-Porqueras, F., Mateos, I., McNamara, P. W., Mendes, J., Mendes, L., Nofrarias, M., Paczkowski, S., Perreur-Lloyd, M., Petiteau, A., Pivato, P., Plagnol, E., Ramos-Castro, J., Reiche, J., Robertson, D. I., Rivas, F., Russano, G., Slutsky, J., Sopuerta, C. F., Sumner, T., Texier, D., Thorpe, J. I., Vetrugno, D., Vitale, S., Wanner, G., Ward, H., Wass, P. J., Weber, W. J., Wissel, L., Wittchen, A., and Zweifel, P.
Subjects: Physics - Space Physics, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: We report on the results of the LISA Pathfinder (LPF) free-fall mode experiment, in which the control force needed to compensate the quasistatic differential force acting on two test masses is applied intermittently as a series of "impulse" forces lasting a few seconds and separated by roughly 350 s periods of true free fall. This represents an alternative to the normal LPF mode of operation in which this balancing force is applied continuously, with the advantage that the acceleration noise during free fall is measured in the absence of the actuation force, thus eliminating associated noise and force calibration errors. The differential acceleration noise measurement presented here with the free-fall mode agrees with noise measured with the continuous actuation scheme, representing an important and independent confirmation of the LPF result. An additional measurement with larger actuation forces also shows that the technique can be used to eliminate actuation noise when this is a dominant factor.
Published: 2019
Full Text: View/download PDF

10. Temperature stability in the sub-milliHertz band with LISA Pathfinder

Author: Armano, M., Audley, H., Baird, J., Binetruy, P., Born, M., Bortoluzzi, D., Castelli, E., Cavalleri, A., Cesarini, A., Cruise, A. M., Danzmann, K., Silva, M. de Deus, Diepholz, I., Dixon, G., Dolesi, R., Ferraioli, L., Ferroni, V., Fitzsimons, E. D., Freschi, M., Gesa, L., Gibert, F., Giardini, D., Giusteri, R., Grimani, C., Grzymisch, J., Harrison, I., Heinzel, G., Hewitson, M., Hollington, D., Hoyland, D., Hueller, M., Inchauspé, H., Jennrich, O., Jetzer, P., Karnesis, N., Kaune, B., Korsakova, N., Killow, C. J., Lobo, J. A., Lloro, I., Liu, L., López-Zaragoza, J. P., Maarschalkerweerd, R., Mance, D., Mansanet, C., Martín, V., Martin-Polo, L., Martino, J., Martin-Porqueras, F., Mateos, I., McNamara, P. W., Mendes, J., Mendes, L., Meshksar, N., Nofrarias, M., Paczkowski, S., Perreur-Lloyd, M., Petiteau, A., Pivato, P., Plagnol, E., Ramos-Castro, J., Reiche, J., Robertson, D. I., Rivas, F., Russano, G., Sanjuán, J., Slutsky, J., Sopuerta, C. F., Sumner, T., Texier, D., Thorpe, J. I., Trenkel, C., Vetrugno, D., Vitale, S., Wanner, G., Ward, H., Wass, P. J., Wealthy, D., Weber, W. J., Wissel, L., Wittchen, A., and Zweifel, P.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics, General Relativity and Quantum Cosmology
Abstract: LISA Pathfinder (LPF) was a technology pioneering mission designed to test key technologies required for gravitational wave detection in space. In the low frequency regime (milli-Hertz and below), where space-based gravitational wave observatories will operate, temperature fluctuations play a crucial role since they can couple into the interferometric measurement and the test masses' free-fall accuracy in many ways. A dedicated temperature measurement subsystem, with noise levels in 10$\,\mu$K$\,$Hz$^{-1/2}$ down to $1\,$mHz was part of the diagnostics unit on board LPF. In this paper we report on the temperature measurements throughout mission operations, characterize the thermal environment, estimate transfer functions between different locations and report temperature stability (and its time evolution) at frequencies as low as 10$\,\mu$Hz, where typically values around $1\,$K$\,$Hz$^{-1/2}$ were measured., Comment: 13 pages, 16 figures. MNRAS LaTeX style file version 3.0
Published: 2019
Full Text: View/download PDF

11. Micrometeoroid Events in LISA Pathfinder

Author: Thorpe, James Ira, Slutsky, Jacob, Baker, John, Littenberg, Tyson, Hourihane, Sophie, Pagane, Nicole, Pokorny, Petr, Janches, Diego, Armano, Michele, Audley, Heather, Auger, G., Baird, Jonathan, Bassan, Massimo, Binetruy, Pierre, Born, Michael, Bortoluzzi, D., Brandt, N., Caleno, M., Cavalleri, A, Cesarini, A, Cruise, A. M., Danzmann, K., Silva, M. de Deus, De Rosa, R., Di Fiore, L., Diepholz, I., Dixon, G., Dolesi, R., Dunbar, N., Ferraioli, L., Ferroni, V., Fitzsimons, E., Flatscher, R., Freschi, M., Marirrodriga, C. Garcia, Gerndt, R., Gesa, L., Gibert, F., Giardini, D., Giusteri, R., Grado, A., Grimani, C., Gryzmisch, J., Harrison, I., Heinzel, G., Hewitson, M., Hollington, D., Hoyland, D., Hueller, M., Inchauspe, H., Jennrich, O., Jetzer, P., Johlander, B., Karnesis, N., Kaune, B., Korsakova, N., Killow, C., Lobo, J. A., Lloro, I., Liu, L., Lopez-Zaragoza, J. P., Maarschalkerweerd, R., Mance, D., Martin, V., Martin-Polo, L., Martino, J., Martin-Porqueras, F., Madden, S., Mateos, I., McNamara, P. W., Mendes, J., Mendes, L., Nofarias, M., Paczkowski, S., Perreur-Lloyd, M., Petiteau, A., Pivato, P., Plagnol, E., Prat, P., Ragnit, U., Ramos-Castro, J., Reiche, J., Robertson, D., Rozemeijer, H., Rivas, F., Russano, G., Sarra, P., Schleicher, A., Shaul, D., Soperta, C., Stanga, R., Sumner, T., Texier, D., Trobs, M., Vetrungno, D., Vitale, S., Wanner, G., Ward, H., Wass, P., Wealthy, D., Weber, W. J., Wissel, L., Wittchen, A., Zambotti, A., Zanoni, C., Ziegler, T., and Zweifel, P.
Subjects: Astrophysics - Earth and Planetary Astrophysics
Abstract: The zodiacal dust complex, a population of dust and small particles that pervades the Solar System, provides important insight into the formation and dynamics of planets, comets, asteroids, and other bodies. Here we present a new set of data obtained using a novel technique: direct measurements of momentum transfer to a spacecraft from individual particle impacts. This technique is made possible by the extreme precision of the instruments flown on the LISA Pathfinder spacecraft, a technology demonstrator for a future space-based gravitational wave observatory that operated near the first Sun-Earth Lagrange point from early 2016 through Summer of 2017. Using a simple model of the impacts and knowledge of the control system, we show that it is possible to detect impacts and measure properties such as the transferred momentum (related to the particle's mass and velocity), direction of travel, and location of impact on the spacecraft. In this paper, we present the results of a systematic search for impacts during 4348 hours of Pathfinder data. We report a total of 54 candidates with momenta ranging from 0.2$\,\mu\textrm{Ns}$ to 230$\,\mu\textrm{Ns}$. We furthermore make a comparison of these candidates with models of micrometeoroid populations in the inner solar system including those resulting from Jupiter-family comets, Oort-cloud comets, Hailey-type comets, and Asteroids. We find that our measured population is consistent with a population dominated by Jupiter-family comets with some evidence for a smaller contribution from Hailey-type comets. This is in agreement with consensus models of the zodiacal dust complex in the momentum range sampled by LISA Pathfinder., Comment: 22 pages, 14 figures, accepted in ApJ
Published: 2019
Full Text: View/download PDF

12. Forbush decreases and $<$ 2-day GCR flux non-recurrent variations studied with LISA Pathfinder

Author: Grimani, C., Armano, M., Audley, H., Baird, J., Benella, S., Binetruy, P., Born, M., Bortoluzzi, D., Castelli, E., Cavalleri, A., Cesarini, A., Cruise, A. M., Danzmann, K., Silva, M. de Deus, Diepholz, I., Dixon, G., Dolesi, R., Fabi, M., Ferraioli, L., Ferroni, V., Finetti, N., Fitzsimons, E. D., Freschi, M., Gesa, L., Gibert, F., Giardini, D., Giusteri, R., Grzymisch, J., Harrison, I., Heinzel, G., Hewitson, M., Hollington, D., Hoyland, D., Hueller, M., Inchauspé, H., Jennrich, O., Jetzer, P., Karnesis, N., Kaune, B., Korsakova, N., Killow, C. J., Kudela, K., Laurenza, M., Lobo, J. A., Lloro, I., Liu, L., López-Zaragoza, J. P., Maarschalkerweerd, R., Mance, D., Meshksar, N., Martín, V., Martin-Polo, L., Martino, J., Martin-Porqueras, F., Mateos, I., McNamara, P. W., Mendes, J., Mendes, L., Nofrarias, M., Paczkowski, S., Perreur-Lloyd, M., Petiteau, A., Pivato, P., Plagnol, E., Ramos-Castro, J., Reiche, J., Robertson, D. I., Rivas, F., Russano, G., Slutsky, J., Sopuerta, C. F., Sumner, T., Telloni, D., Texier, D., Thorpe, J. I., Vetrugno, D., Villani, M., Vitale, S., Wanner, G., Ward, H., Wass, P., Weber, W. J., Wissel, L., Wittchen, A., and Zweifel, P.
Subjects: Physics - Space Physics, Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Solar and Stellar Astrophysics
Abstract: Non-recurrent short term variations of the galactic cosmic-ray (GCR) flux above 70 MeV n$^{-1}$ were observed between 2016 February 18 and 2017 July 3 aboard the European Space Agency LISA Pathfinder (LPF) mission orbiting around the Lagrange point L1 at 1.5$\times$10$^6$ km from Earth. The energy dependence of three Forbush decreases (FDs) is studied and reported here. A comparison of these observations with others carried out in space down to the energy of a few tens of MeV n$^{-1}$ shows that the same GCR flux parameterization applies to events of different intensity during the main phase. FD observations in L1 with LPF and geomagnetic storm occurrence is also presented. Finally, the characteristics of GCR flux non-recurrent variations (peaks and depressions) of duration $<$ 2 days and their association with interplanetary structures are investigated. It is found that, most likely, plasma compression regions between subsequent corotating high-speed streams cause peaks, while heliospheric current sheet crossing cause the majority of the depressions.
Published: 2019
Full Text: View/download PDF

13. Experimental results from the ST7 mission on LISA Pathfinder

Author: Anderson, G, Anderson, J, Anderson, M, Aveni, G, Bame, D, Barela, P, Blackman, K, Carmain, A, Chen, L, Cherng, M, Clark, S, Connally, M, Connolly, W, Conroy, D, Cooper, M, Cutler, C, D'Agostino, J, Demmons, N, Dorantes, E, Dunn, C, Duran, M, Ehrbar, E, Evans, J, Fernandez, J, Franklin, G, Girard, M, Gorelik, J, Hruby, V, Hsu, O, Jackson, D, Javidnia, S, Kern, D, Knopp, M, Kolasinski, R, Kuo, C, Le, T, Li, I, Liepack, O, Littlefield, A, Maghami, P, Malik, S, Markley, L, Martin, R, Marrese-Reading, C, Mehta, J, Mennela, J, Miller, D, Nguyen, D, O'Donnell, J, Parikh, R, Plett, G, Ramsey, T, Randolph, T, Rhodes, S, Romero-Wolf, A, Roy, T, Ruiz, A, Shaw, H, Slutsky, J, Spence, D, Stocky, J, Tallon, J, Thorpe, I, Tolman, W, Umfress, H, Valencia, R, Valerio, C, Warner, W, Wellman, J, Willis, P, Ziemer, J, Zwahlen, J, Armano, M, Audley, H, Baird, J, Binetruy, P, Born, a M, Bortoluzzi, D, Castelli, E, Cavalleri, A, Cesarini, A, Cruise, A M, Danzmann, K, Silva, M de Deus, Diepholz, I, Dixon, G, Dolesi, R, Ferraioli, L, Ferroni, V, Fitzsimons, E D, Freschi, M, Gesa, L, Gibert, F, Giardini, D, Giusteri, R, Grimani, C, Grzymisch, J, Harrison, I, Heinzel, G, Hewitson, M, Hollington, D, Hoyland, D, Hueller, M, Inchauspe, H, Jennrich, O, Jetzer, P, Karnesis, N, Kaune, B, Korsakova, N, Killow, C J, Lobo, J A, Lloro, I, Liu, L, Lopez-Zaragoza, J P, Maarschalkerweerd, R, Mance, D, Meshksar, N, Martin, V, Martin-Polo, L, Martino, J, Martin-Porqueras, F, Mateos, I, McNamara, P W, Mendes, J, Mendes, L, Nofrarias, M, Paczkowski, S, Perreur-Lloyd, M, Petiteau, A, Pivato, P, Plagnol, E, Ramos-Castro, J, Reiche, J, Robertson, D I, Rivas, F, Russano, G, Sopuerta, C F, Sumner, T, Texier, D, Vetrugno, D, Vitale, S, Wanner, G, Ward, H, Wass, P J, Weber, W J, Wissel, L, Wittchen, A, and Zweifel, P
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: The Space Technology 7 Disturbance Reduction System (ST7-DRS) is a NASA technology demonstration payload that operated from January 2016 through July of 2017 on the European Space Agency's LISA Pathfinder spacecraft. The joint goal of the NASA and ESA missions was to validate key technologies for a future space-based gravitational wave observatory targeting the source-rich milliHertz band. The two primary components of ST7-DRS are a micropropulsion system based on colloidal micro-Newton thrusters (CMNTs) and a control system that simultaneously controls the attitude and position of the spacecraft and the two free-flying test masses (TMs). This paper presents our main experimental results and summarizes the overall the performance of the CMNTs and control laws. We find that the CMNT performance to be consistent with pre-flight predictions, with a measured system thrust noise on the order of $100\,\textrm{nN}/\sqrt{\textrm{Hz}}$ in the $1\,\textrm{mHz}\leq f \leq 30\,\textrm{mHz}$ band. The control system maintained the TM-spacecraft separation with an RMS error of less than 2$\,$nm and a noise spectral density of less than $3\,\textrm{nm}/\sqrt{\textrm{Hz}}$ in the same band. Thruster calibration measurements yield thrust values consistent with the performance model and ground-based thrust-stand measurements, to within a few percent. We also report a differential acceleration noise between the two test masses with a spectral density of roughly $3\,\textrm{fm}/\textrm{s}^2/\sqrt{\textrm{Hz}}$ in the $1\,\textrm{mHz}\leq f \leq 30\,\textrm{mHz}$ band, slightly less than twice as large as the best performance reported with the baseline LISA Pathfinder configuration and below the current requirements for the Laser Interferometer Space Antenna (LISA) mission.
Published: 2018
Full Text: View/download PDF

14. Precision Charge Control for Isolated Free-Falling Test Masses: LISA Pathfinder Results

Author: Armano, M., Audley, H., Baird, J., Binetruy, P., Born, M., Bortoluzzi, D., Castelli, E., Cavalleri, A., Cesarini, A., Cruise, A. M., Danzmann, K., Silva, M. de Deus, Diepholz, I., Dixon, G., Dolesi, R., Ferraioli, L., Ferroni, V., Fitzsimons, E. D., Freschi, M., Gesa, L., Giardini, D., Gibert, F., Giusteri, R., Grimani, C., Grzymisch, J., Harrison, I., Heinzel, G., Hewitson, M., Hollington, D., Hoyland, D., Hueller, M., Inchauspé, H., Jennrich, O., Jetzer, P., Karnesis, N., Kaune, B., Korsakova, N., Killow, C. J., Liu, L., Lloro, I., Lobo, J. A., López-Zaragoza, J. P., Maarschalkerweerd, R., Mailland, F., Mance, D., Martín, V., Martin-Polo, L., Martin-Porqueras, F., Martino, J., Mateos, I., McNamara, P. W., Mendes, J., Mendes, L., Meshskar, N., Nofrarias, M., Paczkowski, S., Perreur-Lloyd, M., Petiteau, A., Pfeil, M., Pivato, P., Plagnol, E., Ramos-Castro, J., Reiche, J., Robertson, D. I., Rivas, F., Russano, G., Santoruvo, G., Sarra, P., Shaul, D., Slutsky, J., Sopuerta, C. F., Sumner, T., Texier, D., Thorpe, J. I., Trenkel, C., Vetrugno, D., Vitale, S., Wanner, G., Ward, H., Waschke, S., Wass, P. J., Weber, W. J., Wissel, L., Wittchen, A., and Zweifel, P.
Subjects: Physics - Instrumentation and Detectors
Abstract: The LISA Pathfinder charge management device was responsible for neutralising the cosmic ray induced electric charge that inevitably accumulated on the free-falling test masses at the heart of the experiment. We present measurements made on ground and in-flight that quantify the performance of this contactless discharge system which was based on photo-emission under UV illumination. In addition, a two-part simulation is described that was developed alongside the hardware. Modelling of the absorbed UV light within the Pathfinder sensor was carried out with the GEANT4 software toolkit and a separate MATLAB charge transfer model calculated the net photocurrent between the test masses and surrounding housing in the presence of AC and DC electric fields. We confront the results of these models with observations and draw conclusions for the design of discharge systems for future experiments like LISA that will also employ free-falling test masses.
Published: 2018
Full Text: View/download PDF

15. Calibrating the system dynamics of LISA Pathfinder

Author: Armano, M., Audley, H., Baird, J., Binetruy, P., Born, M., Bortoluzzi, D., Castelli, E., Cavalleri, A., Cesarini, A., Cruise, A. M., Danzmann, K., Silva, M. de Deus, Diepholz, I., Dixon, G., Dolesi, R., Ferraioli, L., Ferroni, V., Fitzsimons, E. D., Freschi, M., Gesa, L., Gibert, F., Giardini, D., Giusteri, R., Grimani, C., Grzymisch, J., Harrison, I., Heinzel, G., Hewitson, M., Hollington, D., Hoyland, D., Hueller, M., Inchauspé, H., Jennrich, O., Jetzer, P., Karnesis, N., Kaune, B., Korsakova, N., Killow, C. J., Lobo, J. A., Lloro, I., Liu, L., López-Zaragoza, J. P., Maarschalkerweerd, R., Mance, D., Meshksar, N., Martín, V., Martin-Polo, L., Martino, J., Martin-Porqueras, F., Mateos, I., McNamara, P. W., Mendes, J., Mendes, L., Nofrarias, M., Paczkowski, S., Perreur-Lloyd, M., Petiteau, A., Pivato, P., Plagnol, E., Ramos-Castro, J., Reiche, J., Robertson, D. I., Rivas, F., Russano, G., Slutsky, J., Sopuerta, C. F., Sumner, T., Texier, D., Thorpe, J. I., Vetrugno, D., Vitale, S., Wanner, G., Ward, H., Wass, P., Weber, W. J., Wissel, L., Wittchen, A., and Zweifel, P.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: LISA Pathfinder (LPF) was a European Space Agency mission with the aim to test key technologies for future space-borne gravitational-wave observatories like LISA. The main scientific goal of LPF was to demonstrate measurements of differential acceleration between free-falling test masses at the sub-femto-g level, and to understand the residual acceleration in terms of a physical model of stray forces, and displacement readout noise. A key step toward reaching the LPF goals was the correct calibration of the dynamics of LPF, which was a three-body system composed by two test-masses enclosed in a single spacecraft, and subject to control laws for system stability. In this work, we report on the calibration procedures adopted to calculate the residual differential stray force per unit mass acting on the two test-masses in their nominal positions. The physical parameters of the adopted dynamical model are presented, together with their role on LPF performance. The analysis and results of these experiments show that the dynamics of the system was accurately modeled and the dynamical parameters were stationary throughout the mission. Finally, the impact and importance of calibrating system dynamics for future space-based gravitational wave observatories is discussed.
Published: 2018
Full Text: View/download PDF

16. Characteristics and energy dependence of recurrent galactic cosmic-ray flux depressions and of a Forbush decrease with LISA Pathfinder

Author: Armano, M., Audley, H., Baird, J., Bassan, M., Benella, S., Binetruy, P., Born, M., Bortoluzzi, D., Cavalleri, A., Cesarini, A., Cruise, A. M., Danzmann, K., Silva, M. de Deus, Diepholz, I., Dixon, G., Dolesi, R., Fabi, M., Ferraioli, L., Ferroni, V., Finetti, N., Fitzsimons, E. D., Freschi, M., Gesa, L., Gibert, F., Giardini, D., Giusteri, R., Grimani, C., Grzymisch, J., Harrison, I., Heinzel, G., Hewitson, M., Hollington, D., Hoyland, D., Hueller, M., Inchauspé, H., Jennrich, O., Jetzer, P., Karnesis, N., Kaune, B., Korsakova, N., Killow, C. J., Laurenza, M., Lobo, J. A., Lloro, I., Liu, L., López-Zaragoza, J. P., Maarschalkerweerd, R., Mance, D., Martín, V., Martin-Polo, L., Martino, J., Martin-Porqueras, F., Mateos, I., McNamara, P. W., Mendes, J., Mendes, L., Nofrarias, M., Paczkowski, S., Perreur-Lloyd, M., Petiteau, A., Pivato, P., Plagnol, E., Ramos-Castro, J., Reiche, J., Robertson, D. I., Rivas, F., Russano, G., Sabbatini, F., Slutsky, J., Sopuerta, C. F., Sumner, T., Telloni, D., Texier, D., Thorpe, J. I., Vetrugno, D., Vitale, S., Wanner, G., Ward, H., Wass, P., Weber, W. J., Wissel, L., Wittchen, A., Zambotti, A., Zanoni, C., and Zweifel, P.
Subjects: Physics - Space Physics, Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Solar and Stellar Astrophysics
Abstract: Galactic cosmic-ray (GCR) energy spectra observed in the inner heliosphere are modulated by the solar activity, the solar polarity and structures of solar and interplanetary origin. A high counting rate particle detector (PD) aboard LISA Pathfinder (LPF), meant for subsystems diagnostics, was devoted to the measurement of galactic cosmic-ray and solar energetic particle integral fluxes above 70 MeV n$^{-1}$ up to 6500 counts s$^{-1}$. PD data were gathered with a sampling time of 15 s. Characteristics and energy-dependence of GCR flux recurrent depressions and of a Forbush decrease dated August 2, 2016 are reported here. The capability of interplanetary missions, carrying PDs for instrument performance purposes, in monitoring the passage of interplanetary coronal mass ejections (ICMEs) is also discussed.
Published: 2018
Full Text: View/download PDF

17. Measuring the Galactic Cosmic Ray Flux with the LISA Pathfinder Radiation Monitor

Author: Armano, M, Audley, H, Baird, J, Binetruy, P, Born, M, Bortoluzzi, D, Castelli, E, Cavalleri, A, Cesarini, A, Cruise, M, Danzmann, K, Silva, M de Deus, Diepholz, I, Dixon, G, Dolesi, R, Ferraioli, L, Ferroni, V, Finetti, N, Fitzsimons, E D, Freschi, M, Gesa, L, Gibert, F, Giardini, D, Giusteri, R, Grimani, C, Grzymisch, J, Harrison, I, Heinzel, G, Hewitson, M, Hollington, D, Hoyland, D, Hueller, M, Inchauspe, H, Jennrich, O, Jetzer, P, Karnesis, N, Kaune, B, Korsakova, N, Killow, C J, Lobo, J A, Lloro, I, Liu, L, Lopez-Zaragoza, J P, Maarschalkerweerd, R, Mance, D, Meshskar, N, Martin, V, Martin-Polo, L, Martino, J, Martin-Porqueras, F, Mateos, I, McNamara, P W, Mendes, J, Mendes, L, Nofrarias, M, Paczkowski, S, Perreur-Lloyd, M, Petiteau, A, Pivato, P, Plagnol, E, Ramos-Castro, J, Reiche, J, Robertson, D I, Rivas, F, Russano, G, Slutsky, J, Sopuerta, C F, Sumner, T, Texier, D, Thorpe, J I, Vetrugno, D, Vitale, S, Wanner, G, Ward, H, Wass, P, Weber, W J, Wissel, L, Wittchen, A, and Zweifel, P
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: Test mass charging caused by cosmic rays will be a significant source of acceleration noise for space-based gravitational wave detectors like LISA. Operating between December 2015 and July 2017, the technology demonstration mission LISA Pathfinder included a bespoke monitor to help characterise the relationship between test mass charging and the local radiation environment. The radiation monitor made in situ measurements of the cosmic ray flux while also providing information about its energy spectrum. We describe the monitor and present measurements which show a gradual 40% increase in count rate coinciding with the declining phase of the solar cycle. Modulations of up to 10% were also observed with periods of 13 and 26 days that are associated with co-rotating interaction regions and heliospheric current sheet crossings. These variations in the flux above the monitor detection threshold (approximately 70 MeV) are shown to be coherent with measurements made by the IREM monitor on-board the Earth orbiting INTEGRAL spacecraft. Finally we use the measured deposited energy spectra, in combination with a GEANT4 model, to estimate the galactic cosmic ray differential energy spectrum over the course of the mission.
Published: 2017
Full Text: View/download PDF

18. Charge-induced force-noise on free-falling test masses: results from LISA Pathfinder

Author: Armano, M., Audley, H., Auger, G., Baird, J. T., Binetruy, P., Born, M., Bortoluzzi, D., Brandt, N., Bursi, A., Caleno, M., Cavalleri, A., Cesarini, A., Cruise, M., Danzmann, K., Silva, M. de Deus, Diepholz, I., Dolesi, R., Dunbar, N., Ferraioli, L., Ferroni, V., Fitzsimons, E. D., Flatscher, R., Freschi, M., Gallegos, J., Marirrodriga, C. García, Gerndt, R., Gesa, L., Gibert, F., Giardini, D., Giusteri, R., Grimani, C., Grzymisch, J., Harrison, I., Heinzel, G., Hewitson, M., Hollington, D., Hueller, M., Huesler, J., Inchauspé, H., Jennrich, O., Jetzer, P., Johlander, B., Karnesis, N., Kaune, B., Killow, C. J., Korsakova, N., Lloro, I., Liu, L., Maarschalkerweerd, R., Madden, S., Mance, D., Martín, V., Martin-Polo, L., Martino, J., Martin-Porqueras, F., Mateos, I., McNamara, P. W., Mendes, J., Mendes, L., Moroni, A., Nofrarias, M., Paczkowski, S., Perreur-Lloyd, M., Petiteau, A., Pivato, P., Plagnol, E., Prat, P., Ragnit, U., Ramos-Castro, J., Reiche, J., Perez, J. A. Romera, Robertson, D. I., Rozemeijer, H., Rivas, F., Russano, G., Sarra, P., Schleicher, A., Slutsky, J., Sopuerta, C., Sumner, T. J., Texier, D., Thorpe, J. I., Trenkel, C., Vetrugno, D., Vitale, S., Wanner, G., Ward, H., Wass, P. J., Wealthy, D., Weber, W. J., Wittchen, A., Zanoni, C., Ziegler, T., and Zweifel, P.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: We report on electrostatic measurements made on board the European Space Agency mission LISA Pathfinder. Detailed measurements of the charge-induced electrostatic forces exerted on free-falling test masses (TMs) inside the capacitive gravitational reference sensor are the first made in a relevant environment for a space-based gravitational wave detector. Employing a combination of charge control and electric-field compensation, we show that the level of charge-induced acceleration noise on a single TM can be maintained at a level close to 1.0 fm/s^2/sqrt(Hz) across the 0.1-100 mHz frequency band that is crucial to an observatory such as LISA. Using dedicated measurements that detect these effects in the differential acceleration between the two test masses, we resolve the stochastic nature of the TM charge build up due to interplanetary cosmic rays and the TM charge-to-force coupling through stray electric fields in the sensor. All our measurements are in good agreement with predictions based on a relatively simple electrostatic model of the LISA Pathfinder instrument., Comment: 9 Pages, 3 figures
Published: 2017
Full Text: View/download PDF

19. Sensor noise in LISA Pathfinder : Laser frequency noise and its coupling to the optical test mass readout

Author: Armano, M., primary, Audley, H., additional, Baird, J., additional, Binetruy, P., additional, Born, M., additional, Bortoluzzi, D., additional, Brandt, N., additional, Castelli, E., additional, Cavalleri, A., additional, Cesarini, A., additional, Cruise, A. M., additional, Danzmann, K., additional, de Deus Silva, M., additional, Diepholz, I., additional, Dixon, G., additional, Dolesi, R., additional, Ferraioli, L., additional, Ferroni, V., additional, Fitzsimons, E. D., additional, Flatscher, R., additional, Freschi, M., additional, García, A., additional, Gerndt, R., additional, Gesa, L., additional, Giardini, D., additional, Gibert, F., additional, Giusteri, R., additional, Grimani, C., additional, Grzymisch, J., additional, Guzman, F., additional, Harrison, I., additional, Hartig, M.-S., additional, Hechenblaikner, G., additional, Heinzel, G., additional, Hewitson, M., additional, Hollington, D., additional, Hoyland, D., additional, Hueller, M., additional, Inchauspé, H., additional, Jennrich, O., additional, Jetzer, P., additional, Johann, U., additional, Johlander, B., additional, Karnesis, N., additional, Kaune, B., additional, Killow, C. J., additional, Korsakova, N., additional, Lobo, J. A., additional, López-Zaragoza, J. P., additional, Maarschalkerweerd, R., additional, Mance, D., additional, Martín, V., additional, Martin-Polo, L., additional, Martin-Porqueras, F., additional, Martino, J., additional, McNamara, P. W., additional, Mendes, J., additional, Mendes, L., additional, Meshksar, N., additional, Monsky, A., additional, Nofrarias, M., additional, Paczkowski, S., additional, Perreur-Lloyd, M., additional, Petiteau, A., additional, Plagnol, E., additional, Ramos-Castro, J., additional, Reiche, J., additional, Rivas, F., additional, Robertson, D. I., additional, Russano, G., additional, Sanjuan, J., additional, Slutsky, J., additional, Sopuerta, C. F., additional, Steier, F., additional, Sumner, T., additional, Texier, D., additional, Thorpe, J. I., additional, Vetrugno, D., additional, Vitale, S., additional, Wand, V., additional, Wanner, G., additional, Ward, H., additional, Wass, P. J., additional, Weber, W. J., additional, Wissel, L., additional, Wittchen, A., additional, and Zweifel, P., additional
Published: 2024
Full Text: View/download PDF

20. Optimal design of calibration signals in space borne gravitational wave detectors

Author: Nofrarias, M., Karnesis, N., Gibert, F., Armano, M., Danzmann, H. Audley. K., Diepholz, I., Dolesi, R., Ferraioli, L., Ferroni, V., Hewitson, M., Hueller, M., Inchauspe, H., Jennrich, O., McNamara, N. Korsakova. P. W., Plagnol, E., Thorpe, J. I., Vetrugno, D., Vitale, S., Wass, P., and Weber, W. J.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics, General Relativity and Quantum Cosmology
Abstract: Future space borne gravitational wave detectors will require a precise definition of calibration signals to ensure the achievement of their design sensitivity. The careful design of the test signals plays a key role in the correct understanding and characterisation of these instruments. In that sense, methods achieving optimal experiment designs must be considered as complementary to the parameter estimation methods being used to determine the parameters describing the system. The relevance of experiment design is particularly significant for the LISA Pathfinder mission, which will spend most of its operation time performing experiments to characterise key technologies for future space borne gravitational wave observatories. Here we propose a framework to derive the optimal signals ---in terms of minimum parameter uncertainty--- to be injected to these instruments during its calibration phase. We compare our results with an alternative numerical algorithm which achieves an optimal input signal by iteratively improving an initial guess. We show agreement of both approaches when applied to the LISA Pathfinder case., Comment: 12 pages, 6 figures
Published: 2015
Full Text: View/download PDF

21. In-flight testing of the injection of the LISA Pathfinder test mass into a geodesic

Author: Bortoluzzi, D., Vignotto, D., Zambotti, A., Armano, M., Audley, H., Baird, J., Binetruy, P., Born, M., Castelli, E., Cavalleri, A., Cesarini, A., Cruise, A.M., Danzmann, K., de Deus Silva, M., Diepholz, I., Dixon, G., Dolesi, R., Ferraioli, L., Ferroni, V., Fitzsimons, E.D., Freschi, M., Gesa, L., Gibert, F., Giardini, D., Giusteri, R., Grimani, C., Grzymisch, J., Harrison, I., Hartig, M.-S., Heinzel, G., Hewitson, M., Hollington, D., Hoyland, D., Hueller, M., Inchauspé, H., Jennrich, O., Jetzer, P., Karnesis, N., Kaune, B., Korsakova, N., Killow, C.J., Lobo, J.A., Liu, L., López-Zaragoza, J.P., Maarschalkerweerd, R., Mance, D., Meshksar, N., Martín, V., Martin-Polo, L., Martino, J., Martin-Porqueras, F., McNamara, P.W., Mendes, J., Mendes, L., Nofrarias, M., Paczkowski, S., Perreur-Lloyd, M., Petiteau, A., Pivato, P., Plagnol, E., Ramos-Castro, J., Reiche, J., Robertson, D.I., Rivas, F., Russano, G., Slutsky, J., Sopuerta, C.F., Sumner, T., Texier, D., Thorpe, J.I., Vetrugno, D., Vitale, S., Wanner, G., Ward, H., Wass, P.J., Weber, W.J., Wissel, L., Wittchen, A., Zweifel, P., and Zanoni, Carlo
Published: 2021
Full Text: View/download PDF

22. Clinical characteristics and outcomes of vaccinated patients hospitalised with SARS-CoV-2 breakthrough infection: Multi-IPV, a multicentre study in Northern Italy

Author: Lombardi, A, Villa, S, Colaneri, M, Scaglione, G, Bai, F, Varisco, B, Bono, V, Vena, A, Dentone, C, Russo, C, Tettamanti, M, Renisi, G, Viero, G, Azzarà, C, Mantero, M, Peyvandi, F, Bassetti, M, Marchetti, G, Muscatello, A, Nobili, A, Gori, A, Bandera, A, Bosari, S, Scudeller, L, Fusetti, G, Rusconi, L, Dell’Orto, S, Prati, D, Valenti, L, Giovannelli, S, Manunta, M, Lamorte, G, Ferarri, F, Gori., A, Mangioni, D, Alagna, L, Bozzi, G, Lombardi., A, Ungaro, R, Ancona, G, Mussa, M, Mariani, B, Bolis, M, Iannotti, N, Ludovisi, S, Comelli, A, Biscarini, S, Castelli, V, Palomba, E, Fava, M, Peri, C, Saltini, P, Itri, T, Ferroni, V, Pastore, V, Massafra, R, Liparoti, A, Muheberimana, T, Giommi, A, Bianco, R, Chitani, G, Bobbio, C, De Matteis, I, Bonomi, A, Gualtierotti, R, Ferrari, B, Rossio, R, Boasi, N, Pagliaro, E, Massimo, C, De Caro, M, Giachi, A, Montano, N, Vigone, B, Bellocchi, C, Carandina, A, Fiorelli, E, Melli, V, Tobaldini, E, Blasi, F, Aliberti, S, Spotti, M, Terranova, L, Misuraca, S, D’Adda, A, Della Fiore, S, Di Pasquale, M, Mantero., M, Contarini, M, Ori, M, Morlacchi, L, Rossetti, V, Gramegna, A, Pappalettera, M, Cavallini, M, Buscemi, A, Vicenzi, M, Rota, I, Costantino, G, Solbiati, M, Furlan, L, Mancarella, M, Colombo, G, Fanin, A, Passarella, M, Monzani, V, Canetta, C, Rovellini, A, Barbetta, L, Billi, F, Folli, C, Accordino, S, Maira, D, Hu, C, Motta, I, Scaramellini, N, Fracanzani, A, Lombardi, R, Cespiati, A, Cesari, M, Lucchi, T, Proietti, M, Calcaterra, L, Mandelli, C, Coppola, C, Cerizza, A, Pesenti, A, Grasselli, G, Galazzi, A, Nobili., A, Monti, I, Galbussera, A, Crisafulli, E, Girelli, D, Maroccia, A, Gabbiani, D, Busti, F, Vianello, A, Biondan, M, Sartori, F, Faverio, P, Pesci, A, Zucchetti, S, Bonfanti, P, Rossi, M, Beretta, I, Spolti, A, Harari, S, Elia, D, Cassandro, R, Caminati, A, Cipollone, F, Guagnano, M, D’Ardes, D, Rossi, I, Vezzani, F, Spanevello, A, Cherubino, F, Visca, D, Contoli, M, Papi, A, Morandi, L, Battistini, N, Moreo, G, Iannuzzi, P, Fumagalla, D, Leone, S, Lombardi, Andrea, Villa, Simone, Colaneri, Marta, Scaglione, Giovanni, Bai, Francesca, Varisco, Benedetta, Bono, Valeria, Vena, Antonio, Dentone, Chiara, Russo, Chiara, Tettamanti, Mauro, Renisi, Giulia, Viero, Giulia, Azzarà, Cecilia, Mantero, Marco, Peyvandi, Flora, Bassetti, Matteo, Marchetti, Giulia, Muscatello, Antonio, Nobili, Alessandro, Gori, Andrea, Bandera, Alessandra, Bosari, Silvano, Scudeller, Luigia, Fusetti, Giuliana, Rusconi, Laura, Dell’Orto, Silvia, Prati, Daniele, Valenti, Luca, Giovannelli, Silvia, Manunta, Maria, Lamorte, Giuseppe, Ferarri, Francesca, Gori. , Andrea, Mangioni, Davide, Alagna, Laura, Bozzi, Giorgio, Lombardi. , Andrea, Ungaro, Riccardo, Ancona, Giuseppe, Mussa, Marco, Mariani, Bianca Veronica, Bolis, Matteo, Iannotti, Nathalie, Ludovisi, Serena, Comelli, Agnese, Biscarini, Simona, Castelli, Valeria, Palomba, Emanuele, Fava, Marco, Peri, Carlo Alberto, Saltini, Paola, Itri, Teresa, Ferroni, Valentina, Pastore, Valeria, Massafra, Roberta, Liparoti, Arianna, Muheberimana, Toussaint, Giommi, Alessandro, Bianco, Rosaria, Chitani, Grazia Eliana, Bobbio, Chiara, De Matteis, Irene, Bonomi, Angelo Bianchi, Gualtierotti, Roberta, Ferrari, Barbara, Rossio, Raffaella, Boasi, Nadia, Pagliaro, Erica, Massimo, Costanza, De Caro, Michele, Giachi, Andrea, Montano, Nicola, Vigone, Barbara, Bellocchi, Chiara, Carandina, Angelica, Fiorelli, Elisa, Melli, Valerie, Tobaldini, Eleonora, Blasi, Francesco, Aliberti, Stefano, Spotti, Maura, Terranova, Leonardo, Misuraca, Sofia, D’Adda, Alice, Della Fiore, Silvia, Di Pasquale, Marta, Mantero. , Marco, Contarini, Martina, Ori, Margherita, Morlacchi, Letizia, Rossetti, Valeria, Gramegna, Andrea, Pappalettera, Maria, Cavallini, Mirta, Buscemi, Agata, Vicenzi, Marco, Rota, Irena, Costantino, Giorgio, Solbiati, Monica, Furlan, Ludovico, Mancarella, Marta, Colombo, Giulia, Colombo, Giorgio, Fanin, Alice, Passarella, Mariele, Monzani, Valter, Canetta, Ciro, Rovellini, Angelo, Barbetta, Laura, Billi, Filippo, Folli, Christian, Accordino, Silvia, Maira, Diletta, Hu, Cinzia Maria, Motta, Irene, Scaramellini, Natalia, Fracanzani, Anna Ludovica, Lombardi, Rosa, Cespiati, Annalisa, Cesari, Matteo, Lucchi, Tiziano, Proietti, Marco, Calcaterra, Laura, Mandelli, Clara, Coppola, Carlotta, Cerizza, Arturo, Pesenti, Antonio Maria, Grasselli, Giacomo, Galazzi, Alessandro, Nobili. , Alessandro, Monti, Igor, Galbussera, Alessia Antonella, Crisafulli, Ernesto, Girelli, Domenico, Maroccia, Alessio, Gabbiani, Daniele, Busti, Fabiana, Vianello, Alice, Biondan, Marta, Sartori, Filippo, Faverio, Paola, Pesci, Alberto, Zucchetti, Stefano, Bonfanti, Paolo, Rossi, Marianna, Beretta, Ilaria, Spolti, Anna, Harari, Sergio, Elia, Davide, Cassandro, Roberto, Caminati, Antonella, Cipollone, Francesco, Guagnano, Maria Teresa, D’Ardes, Damiano, Rossi, Ilaria, Vezzani, Francesca, Spanevello, Antonio, Cherubino, Francesca, Visca, Dina, Contoli, Marco, Papi, Alberto, Morandi, Luca, Battistini, Nicholas, Moreo, Guido Luigi, Iannuzzi, Pasqualina, Fumagalla, Daniele, Leone, Sara, Lombardi, A, Villa, S, Colaneri, M, Scaglione, G, Bai, F, Varisco, B, Bono, V, Vena, A, Dentone, C, Russo, C, Tettamanti, M, Renisi, G, Viero, G, Azzarà, C, Mantero, M, Peyvandi, F, Bassetti, M, Marchetti, G, Muscatello, A, Nobili, A, Gori, A, Bandera, A, Bosari, S, Scudeller, L, Fusetti, G, Rusconi, L, Dell’Orto, S, Prati, D, Valenti, L, Giovannelli, S, Manunta, M, Lamorte, G, Ferarri, F, Gori., A, Mangioni, D, Alagna, L, Bozzi, G, Lombardi., A, Ungaro, R, Ancona, G, Mussa, M, Mariani, B, Bolis, M, Iannotti, N, Ludovisi, S, Comelli, A, Biscarini, S, Castelli, V, Palomba, E, Fava, M, Peri, C, Saltini, P, Itri, T, Ferroni, V, Pastore, V, Massafra, R, Liparoti, A, Muheberimana, T, Giommi, A, Bianco, R, Chitani, G, Bobbio, C, De Matteis, I, Bonomi, A, Gualtierotti, R, Ferrari, B, Rossio, R, Boasi, N, Pagliaro, E, Massimo, C, De Caro, M, Giachi, A, Montano, N, Vigone, B, Bellocchi, C, Carandina, A, Fiorelli, E, Melli, V, Tobaldini, E, Blasi, F, Aliberti, S, Spotti, M, Terranova, L, Misuraca, S, D’Adda, A, Della Fiore, S, Di Pasquale, M, Mantero., M, Contarini, M, Ori, M, Morlacchi, L, Rossetti, V, Gramegna, A, Pappalettera, M, Cavallini, M, Buscemi, A, Vicenzi, M, Rota, I, Costantino, G, Solbiati, M, Furlan, L, Mancarella, M, Colombo, G, Fanin, A, Passarella, M, Monzani, V, Canetta, C, Rovellini, A, Barbetta, L, Billi, F, Folli, C, Accordino, S, Maira, D, Hu, C, Motta, I, Scaramellini, N, Fracanzani, A, Lombardi, R, Cespiati, A, Cesari, M, Lucchi, T, Proietti, M, Calcaterra, L, Mandelli, C, Coppola, C, Cerizza, A, Pesenti, A, Grasselli, G, Galazzi, A, Nobili., A, Monti, I, Galbussera, A, Crisafulli, E, Girelli, D, Maroccia, A, Gabbiani, D, Busti, F, Vianello, A, Biondan, M, Sartori, F, Faverio, P, Pesci, A, Zucchetti, S, Bonfanti, P, Rossi, M, Beretta, I, Spolti, A, Harari, S, Elia, D, Cassandro, R, Caminati, A, Cipollone, F, Guagnano, M, D’Ardes, D, Rossi, I, Vezzani, F, Spanevello, A, Cherubino, F, Visca, D, Contoli, M, Papi, A, Morandi, L, Battistini, N, Moreo, G, Iannuzzi, P, Fumagalla, D, Leone, S, Lombardi, Andrea, Villa, Simone, Colaneri, Marta, Scaglione, Giovanni, Bai, Francesca, Varisco, Benedetta, Bono, Valeria, Vena, Antonio, Dentone, Chiara, Russo, Chiara, Tettamanti, Mauro, Renisi, Giulia, Viero, Giulia, Azzarà, Cecilia, Mantero, Marco, Peyvandi, Flora, Bassetti, Matteo, Marchetti, Giulia, Muscatello, Antonio, Nobili, Alessandro, Gori, Andrea, Bandera, Alessandra, Bosari, Silvano, Scudeller, Luigia, Fusetti, Giuliana, Rusconi, Laura, Dell’Orto, Silvia, Prati, Daniele, Valenti, Luca, Giovannelli, Silvia, Manunta, Maria, Lamorte, Giuseppe, Ferarri, Francesca, Gori. , Andrea, Mangioni, Davide, Alagna, Laura, Bozzi, Giorgio, Lombardi. , Andrea, Ungaro, Riccardo, Ancona, Giuseppe, Mussa, Marco, Mariani, Bianca Veronica, Bolis, Matteo, Iannotti, Nathalie, Ludovisi, Serena, Comelli, Agnese, Biscarini, Simona, Castelli, Valeria, Palomba, Emanuele, Fava, Marco, Peri, Carlo Alberto, Saltini, Paola, Itri, Teresa, Ferroni, Valentina, Pastore, Valeria, Massafra, Roberta, Liparoti, Arianna, Muheberimana, Toussaint, Giommi, Alessandro, Bianco, Rosaria, Chitani, Grazia Eliana, Bobbio, Chiara, De Matteis, Irene, Bonomi, Angelo Bianchi, Gualtierotti, Roberta, Ferrari, Barbara, Rossio, Raffaella, Boasi, Nadia, Pagliaro, Erica, Massimo, Costanza, De Caro, Michele, Giachi, Andrea, Montano, Nicola, Vigone, Barbara, Bellocchi, Chiara, Carandina, Angelica, Fiorelli, Elisa, Melli, Valerie, Tobaldini, Eleonora, Blasi, Francesco, Aliberti, Stefano, Spotti, Maura, Terranova, Leonardo, Misuraca, Sofia, D’Adda, Alice, Della Fiore, Silvia, Di Pasquale, Marta, Mantero. , Marco, Contarini, Martina, Ori, Margherita, Morlacchi, Letizia, Rossetti, Valeria, Gramegna, Andrea, Pappalettera, Maria, Cavallini, Mirta, Buscemi, Agata, Vicenzi, Marco, Rota, Irena, Costantino, Giorgio, Solbiati, Monica, Furlan, Ludovico, Mancarella, Marta, Colombo, Giulia, Colombo, Giorgio, Fanin, Alice, Passarella, Mariele, Monzani, Valter, Canetta, Ciro, Rovellini, Angelo, Barbetta, Laura, Billi, Filippo, Folli, Christian, Accordino, Silvia, Maira, Diletta, Hu, Cinzia Maria, Motta, Irene, Scaramellini, Natalia, Fracanzani, Anna Ludovica, Lombardi, Rosa, Cespiati, Annalisa, Cesari, Matteo, Lucchi, Tiziano, Proietti, Marco, Calcaterra, Laura, Mandelli, Clara, Coppola, Carlotta, Cerizza, Arturo, Pesenti, Antonio Maria, Grasselli, Giacomo, Galazzi, Alessandro, Nobili. , Alessandro, Monti, Igor, Galbussera, Alessia Antonella, Crisafulli, Ernesto, Girelli, Domenico, Maroccia, Alessio, Gabbiani, Daniele, Busti, Fabiana, Vianello, Alice, Biondan, Marta, Sartori, Filippo, Faverio, Paola, Pesci, Alberto, Zucchetti, Stefano, Bonfanti, Paolo, Rossi, Marianna, Beretta, Ilaria, Spolti, Anna, Harari, Sergio, Elia, Davide, Cassandro, Roberto, Caminati, Antonella, Cipollone, Francesco, Guagnano, Maria Teresa, D’Ardes, Damiano, Rossi, Ilaria, Vezzani, Francesca, Spanevello, Antonio, Cherubino, Francesca, Visca, Dina, Contoli, Marco, Papi, Alberto, Morandi, Luca, Battistini, Nicholas, Moreo, Guido Luigi, Iannuzzi, Pasqualina, Fumagalla, Daniele, and Leone, Sara
Abstract: Background: Despite the well-known efficacy of anti-COVID-19 vaccines in preventing morbidity and mortality, several vaccinated individuals are diagnosed with SARS-CoV-2 breakthrough infection, which might require hospitalisation. This multicentre, observational, and retrospective study aimed to investigate the clinical characteristics and outcomes of vaccinated vs. non-vaccinated patients, both hospitalised with SARS-CoV-2 infection in 3 major hospitals in Northern Italy. Methods: Data collection was retrospective, and paper and electronic medical records of adult patients with a diagnosed SARS-CoV-2 infection were pseudo-anonymised and analysed. Vaccinated and non-vaccinated individuals were manually paired, using a predetermined matching criterion (similar age, gender, and date of hospitalisation). Demographic, clinical, treatment, and outcome data were compared between groups differing by vaccination status using Pearson's Chi-square and Mann-Whitney tests. Moreover, multiple logistic regression analyses were performed to assess the impact of vaccination status on ICU admission or intra-hospital mortality. Results: Data from 360 patients were collected. Vaccinated patients presented with a higher prevalence of relevant comorbidities, like kidney replacement therapy or haematological malignancy, despite a milder clinical presentation at the first evaluation. Non-vaccinated patients required intensive care more often than their vaccinated counterparts (8.8% vs. 1.7%, p = 0.002). Contrariwise, no difference in intra-hospital mortality was observed between the two groups (19% vs. 20%, p = 0.853). These results were confirmed by multivariable logistic regressions, which showed that vaccination was significantly associated with decreased risk of ICU admission (aOR=0.172, 95%CI: 0.039–0.542, p = 0.007), but not of intra-hospital mortality (aOR=0.996, 95%CI: 0.582–1.703, p = 0.987). Conclusions: This study provides real-world data on vaccinated patients hospitalised wit
Published: 2024

23. Free-flight experiments in LISA Pathfinder

Author: Armano, M., Audley, H., Auger, G., Baird, J., Binetruy, P., Born, M., Bortoluzzi, D., Brandt, N., Bursi, A., Caleno, M., Cavalleri, A., Cesarini, A., Cruise, M., Cutler, C., Danzmann, K., Diepholz, I., Dolesi, R., Dunbar, N., Ferraioli, L., Ferroni, V., Fitzsimons, E., Freschi, M., Gallegos, J., Marirrodriga, C. Garcia., Gerndt, R., Gesa, LI., Gibert, F., Giardini, D., Giusteri, R., Grimani, C., Harrison, I., Heinzel, G., Hewitson, M., Hollington, D., Hueller, M., Huesler, J., Inchauspe, H., Jennrich, O., Jetzer, P., Johlander, B., Karnesis, N., Kaune, B., Korsakova, N., Killow, C., Lloro, I., Maarschalkerweerd, R., Madden, S., Maghami, P., Mance, D., Martin, V., Martin-Porqueras, F., Mateos, I., McNamara, P., Mendes, J., Mendes, L., Moroni, A., Nofrarias, M., Paczkowski, S., Perreur-Lloyd, M., Petiteau, A., Pivato, P., Plagnol, E., Prat, P., Ragnit, U., Ramos-Castro, J., Reiche, J., Perez, J. A. Romera., Robertson, D., Rozemeijer, H., Russano, G., Sarra, P., Schleicher, A., Slutsky, J., Sopuerta, C. F., Sumner, T., Texier, D., Thorpe, J., Trenkel, C., Tu, H. B., Vetrugno, D., Vitale, S., Wanner, G., Ward, H., Waschke, S., Wass, P., Wealthy, D., Wen, S., Weber, W., Wittchen, A., Zanoni, C., Ziegler, T., and Zweifel, P.
Subjects: General Relativity and Quantum Cosmology, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: The LISA Pathfinder mission will demonstrate the technology of drag-free test masses for use as inertial references in future space-based gravitational wave detectors. To accomplish this, the Pathfinder spacecraft will perform drag-free flight about a test mass while measuring the acceleration of this primary test mass relative to a second reference test mass. Because the reference test mass is contained within the same spacecraft, it is necessary to apply forces on it to maintain its position and attitude relative to the spacecraft. These forces are a potential source of acceleration noise in the LISA Pathfinder system that are not present in the full LISA configuration. While LISA Pathfinder has been designed to meet it's primary mission requirements in the presence of this noise, recent estimates suggest that the on-orbit performance may be limited by this `suspension noise'. The drift-mode or free-flight experiments provide an opportunity to mitigate this noise source and further characterize the underlying disturbances that are of interest to the designers of LISA-like instruments. This article provides a high-level overview of these experiments and the methods under development to analyze the resulting data., Comment: 13 pages, 5 figures. Accepted to Journal Of Physics, Conference Series. Presented at 10th International LISA Symposium, May 2014, Gainesville, FL, USA
Published: 2014
Full Text: View/download PDF

24. Lung consolidation in a young-age active smoker: An unexpected diagnosis

Author: Bertuccio, F.R., primary, Baio, N., additional, Chino, V., additional, Ferroni, V., additional, Montini, S., additional, Pisanu, L., additional, Cascina, A., additional, Conio, V., additional, Corsico, A.G., additional, and Stella, G.M., additional
Published: 2024
Full Text: View/download PDF

25. Tilt-to-length coupling in LISA Pathfinder: A data analysis

Author: Armano, M., primary, Audley, H., additional, Baird, J., additional, Binetruy, P., additional, Born, M., additional, Bortoluzzi, D., additional, Castelli, E., additional, Cavalleri, A., additional, Cesarini, A., additional, Cruise, A. M., additional, Danzmann, K., additional, de Deus Silva, M., additional, Diepholz, I., additional, Dixon, G., additional, Dolesi, R., additional, Ferraioli, L., additional, Ferroni, V., additional, Fitzsimons, E. D., additional, Freschi, M., additional, Gesa, L., additional, Giardini, D., additional, Gibert, F., additional, Giusteri, R., additional, Grimani, C., additional, Grzymisch, J., additional, Harrison, I., additional, Hartig, M-S., additional, Heinzel, G., additional, Hewitson, M., additional, Hollington, D., additional, Hoyland, D., additional, Hueller, M., additional, Inchauspé, H., additional, Jennrich, O., additional, Jetzer, P., additional, Johann, U., additional, Johlander, B., additional, Karnesis, N., additional, Kaune, B., additional, Killow, C. J., additional, Korsakova, N., additional, Lobo, J. A., additional, López-Zaragoza, J. P., additional, Maarschalkerweerd, R., additional, Mance, D., additional, Martín, V., additional, Martin-Polo, L., additional, Martin-Porqueras, F., additional, Martino, J., additional, McNamara, P. W., additional, Mendes, J., additional, Mendes, L., additional, Meshksar, N., additional, Nofrarias, M., additional, Paczkowski, S., additional, Perreur-Lloyd, M., additional, Petiteau, A., additional, Plagnol, E., additional, Ramos-Castro, J., additional, Reiche, J., additional, Rivas, F., additional, Robertson, D. I., additional, Russano, G., additional, Sanjuan, J., additional, Slutsky, J., additional, Sopuerta, C. F., additional, Sumner, T., additional, Tevlin, L., additional, Texier, D., additional, Thorpe, J. I., additional, Vetrugno, D., additional, Vitale, S., additional, Wanner, G., additional, Ward, H., additional, Wass, P. J., additional, Weber, W. J., additional, Wissel, L., additional, Wittchen, A., additional, and Zweifel, P., additional
Published: 2023
Full Text: View/download PDF

26. The Gravitational Universe

Author: Consortium, The eLISA, Seoane, P. Amaro, Aoudia, S., Audley, H., Auger, G., Babak, S., Baker, J., Barausse, E., Barke, S., Bassan, M., Beckmann, V., Benacquista, M., Bender, P. L., Berti, E., Binétruy, P., Bogenstahl, J., Bonvin, C., Bortoluzzi, D., Brause, N. C., Brossard, J., Buchman, S., Bykov, I., Camp, J., Caprini, C., Cavalleri, A., Cerdonio, M., Ciani, G., Colpi, M., Congedo, G., Conklin, J., Cornish, N., Danzmann, K., de Vine, G., DeBra, D., Freitag, M. Dewi, Di Fiore, L., Aguilo, M. Diaz, Diepholz, I., Dolesi, R., Dotti, M., Barranco, G. Fernández, Ferraioli, L., Ferroni, V., Finetti, N., Fitzsimons, E., Gair, J., Galeazzi, F., Garcia, A., Gerberding, O., Gesa, L., Giardini, D., Gibert, F., Grimani, C., Groot, P., Cervantes, F. Guzman, Haiman, Z., Halloin, H., Heinzel, G., Hewitson, M., Hogan, C., Holz, D., Hornstrup, A., Hoyland, D., Hoyle, C. D., Hueller, M., Hughes, S., Jetzer, P., Kalogera, V., Karnesis, N., Kilic, M., Killow, C., Klipstein, W., Kochkina, E., Korsakova, N., Krolak, A., Larson, S., Lieser, M., Littenberg, T., Livas, J., Lloro, I., Mance, D., Madau, P., Maghami, P., Mahrdt, C., Marsh, T., Mateos, I., Mayer, L., McClelland, D., McKenzie, K., McWilliams, S., Merkowitz, S., Miller, C., Mitryk, S., Moerschell, J., Mohanty, S., Monsky, A., Mueller, G., Müller, V., Nelemans, G., Nicolodi, D., Nissanke, S., Nofrarias, M., Numata, K., Ohme, F., Otto, M., Perreur-Lloyd, M., Petiteau, A., Phinney, E. S., Plagnol, E., Pollack, S., Porter, E., Prat, P., Preston, A., Prince, T., Reiche, J., Richstone, D., Robertson, D., Rossi, E. M., Rosswog, S., Rubbo, L., Ruiter, A., Sanjuan, J., Sathyaprakash, B. S., Schlamminger, S., Schutz, B., Schütze, D., Sesana, A., Shaddock, D., Shah, S., Sheard, B., Sopuerta, C. F., Spector, A., Spero, R., Stanga, R., Stebbins, R., Stede, G., Steier, F., Sumner, T., Sun, K. -X., Sutton, A., Tanaka, T., Tanner, D., Thorpe, I., Tröbs, M., Tinto, M., Tu, H. -B., Vallisneri, M., Vetrugno, D., Vitale, S., Volonteri, M., Wand, V., Wang, Y., Wanner, G., Ward, H., Ware, B., Wass, P., Weber, W. J., Yu, Y., Yunes, N., and Zweifel, P.
Subjects: Astrophysics - Cosmology and Extragalactic Astrophysics, General Relativity and Quantum Cosmology
Abstract: The last century has seen enormous progress in our understanding of the Universe. We know the life cycles of stars, the structure of galaxies, the remnants of the big bang, and have a general understanding of how the Universe evolved. We have come remarkably far using electromagnetic radiation as our tool for observing the Universe. However, gravity is the engine behind many of the processes in the Universe, and much of its action is dark. Opening a gravitational window on the Universe will let us go further than any alternative. Gravity has its own messenger: Gravitational waves, ripples in the fabric of spacetime. They travel essentially undisturbed and let us peer deep into the formation of the first seed black holes, exploring redshifts as large as z ~ 20, prior to the epoch of cosmic re-ionisation. Exquisite and unprecedented measurements of black hole masses and spins will make it possible to trace the history of black holes across all stages of galaxy evolution, and at the same time constrain any deviation from the Kerr metric of General Relativity. eLISA will be the first ever mission to study the entire Universe with gravitational waves. eLISA is an all-sky monitor and will offer a wide view of a dynamic cosmos using gravitational waves as new and unique messengers to unveil The Gravitational Universe. It provides the closest ever view of the early processes at TeV energies, has guaranteed sources in the form of verification binaries in the Milky Way, and can probe the entire Universe, from its smallest scales around singularities and black holes, all the way to cosmological dimensions., Comment: 20 pages; submitted to the European Space Agency on May 24th, 2013 for the L2/L3 selection of ESA's Cosmic Vision program
Published: 2013

27. Measuring the Galactic Cosmic Ray flux with the LISA Pathfinder radiation monitor

Author: Armano, M., Audley, H., Baird, J., Binetruy, P., Born, M., Bortoluzzi, D., Castelli, E., Cavalleri, A., Cesarini, A., Cruise, A.M., Danzmann, K., de Deus Silva, M., Diepholz, I., Dixon, G., Dolesi, R., Ferraioli, L., Ferroni, V., Finetti, N., Fitzsimons, E.D., Freschi, M., Gesa, L., Gibert, F., Giardini, D., Giusteri, R., Grimani, C., Grzymisch, J., Harrison, I., Heinzel, G., Hewitson, M., Hollington, D., Hoyland, D., Hueller, M., Inchauspé, H., Jennrich, O., Jetzer, P., Karnesis, N., Kaune, B., Korsakova, N., Killow, C.J., Lobo, J.A., Lloro, I., Liu, L., Lopez-Zaragoza, J.P., Maarschalkerweerd, R., Mance, D., Meshskar, N., Martín, V., Martin-Polo, L., Martino, J., Martin-Porqueras, F., Mateos, I., McNamara, P.W., Mendes, J., Mendes, L., Nofrarias, M., Paczkowski, S., Perreur-Lloyd, M., Petiteau, A., Pivato, P., Plagnol, E., Ramos-Castro, J., Reiche, J., Robertson, D.I., Rivas, F., Russano, G., Slutsky, J., Sopuerta, C.F., Sumner, T., Texier, D., Thorpe, J.I., Vetrugno, D., Vitale, S., Wanner, G., Ward, H., Wass, P., Weber, W.J., Wissel, L., Wittchen, A., and Zweifel, P.
Published: 2018
Full Text: View/download PDF

28. External validation of risk scores to predict in-hospital mortality in patients hospitalized due to coronavirus disease 2019

Author: Hassan, S, Ramspek, C, Ferrari, B, van Diepen, M, Rossio, R, Knevel, R, la Mura, V, Artoni, A, Martinelli, I, Bandera, A, Nobili, A, Gori, A, Blasi, F, Canetta, C, Montano, N, Rosendaal, F, Peyvandi, F, Bosari, S, Scudeller, L, Fusetti, G, Rusconi, L, Dell'Orto, S, Prati, D, Valenti, L, Giovannelli, S, Manunta, M, Lamorte, G, Ferarri, F, Muscatello, A, Mangioni, D, Alagna, L, Bozzi, G, Lombardi, A, Ungaro, R, Ancona, G, Zuglian, G, Bolis, M, Iannotti, N, Ludovisi, S, Comelli, A, Renisi, G, Biscarini, S, Castelli, V, Palomba, E, Fava, M, Fortina, V, Peri, C, Saltini, P, Viero, G, Itri, T, Ferroni, V, Pastore, V, Massafra, R, Liparoti, A, Muheberimana, T, Giommi, A, Bianco, R, De Azevedo, R, Chitani, G, Gualtierotti, R, Boasi, N, Pagliaro, E, Massimo, C, De Caro, M, Giachi, A, Vigone, B, Bellocchi, C, Carandina, A, Fiorelli, E, Melli, V, Tobaldini, E, Aliberti, S, Spotti, M, Terranova, L, Misuraca, S, D'Adda, A, Fiore, S, Di Pasquale, M, Mantero, M, Contarini, M, Ori, M, Morlacchi, L, Rossetti, V, Gramegna, A, Pappalettera, M, Cavallini, M, Buscemi, A, Vicenzi, M, Rota, I, Costantino, G, Solbiati, M, Furlan, L, Mancarella, M, Colombo, G, Fanin, A, Passarella, M, Monzani, V, Rovellini, A, Barbetta, L, Billi, F, Folli, C, Accordino, S, Maira, D, Hu, C, Motta, I, Scar-Amellini, N, Fracanzani, A, Lombardi, R, Cespiati, A, Cesari, M, Lucchi, T, Proietti, M, Calcaterra, L, Mandelli, C, Coppola, C, Cerizza, A, Maria Pesenti, A, Grasselli, G, Galazzi, A, Tet-Tamanti, M, Monti, I, Galbussera, A, Crisafulli, E, Girelli, D, Maroccia, A, Gabbiani, D, Busti, F, Vianello, A, Biondan, M, Sartori, F, Faverio, P, Pesci, A, Zucchetti, S, Bonfanti, P, Rossi, M, Beretta, I, Spolti, A, Harari, S, Elia, D, Cassandro, R, Caminati, A, Cipollone, F, Guagnano, M, D'Ardes, D, Rossi, I, Vezzani, F, Spanevello, A, Cherubino, F, Visca, D, Contoli, M, Papi, A, Morandi, L, Battistini, N, Luigi Moreo, G, Iannuzzi, P, Fumagalli, D, Leone, S, Oud, J, Baysan, M, Wigb, J, van Heurn, L, ter Haar, S, Toppenberg, A, Heerdink, L, van IJlzinga Veenstra, A, Eikenboom, A, Wubbolts, J, Uzorka, J, Lijferink, W, Meier, R, de Jonge, I, Arbous, S, de Boer, M, van der Bom, J, Dekkers, O, Hassan S., Ramspek C. L., Ferrari B., van Diepen M., Rossio R., Knevel R., la Mura V., Artoni A., Martinelli I., Bandera A., Nobili A., Gori A., Blasi F., Canetta C., Montano N., Rosendaal F. R., Peyvandi F., Bosari S., Scudeller L., Fusetti G., Rusconi L., Dell'Orto S., Prati D., Valenti L., Giovannelli S., Manunta M., Lamorte G., Ferarri F., Muscatello A., Mangioni D., Alagna L., Bozzi G., Lombardi A., Ungaro R., Ancona G., Zuglian G., Bolis M., Iannotti N., Ludovisi S., Comelli A., Renisi G., Biscarini S., Castelli V., Palomba E., Fava M., Fortina V., Peri C. A., Saltini P., Viero G., Itri T., Ferroni V., Pastore V., Massafra R., Liparoti A., Muheberimana T., Giommi A., Bianco R., De Azevedo R. M., Chitani G. E., Gualtierotti R., Boasi N., Pagliaro E., Massimo C., De Caro M., Giachi A., Vigone B., Bellocchi C., Carandina A., Fiorelli E., Melli V., Tobaldini E., Aliberti S., Spotti M., Terranova L., Misuraca S., D'Adda A., Fiore S. D., Di Pasquale M., Mantero M., Contarini M., Ori M., Morlacchi L., Rossetti V., Gramegna A., Pappalettera M., Cavallini M., Buscemi A., Vicenzi M., Rota I., Costantino G., Solbiati M., Furlan L., Mancarella M., Colombo G., Fanin A., Passarella M., Monzani V., Rovellini A., Barbetta L., Billi F., Folli C., Accordino S., Maira D., Hu C. M., Motta I., Scar-Amellini N., Fracanzani A. L., Lombardi R., Cespiati A., Cesari M., Lucchi T., Proietti M., Calcaterra L., Mandelli C., Coppola C., Cerizza A., Maria Pesenti A., Grasselli G., Galazzi A., Tet-Tamanti M., Monti I., Galbussera A. A., Crisafulli E., Girelli D., Maroccia A., Gabbiani D., Busti F., Vianello A., Biondan M., Sartori F., Faverio P., Pesci A., Zucchetti S., Bonfanti P., Rossi M., Beretta I., Spolti A., Harari S., Elia D., Cassandro R., Caminati A., Cipollone F., Guagnano M. T., D'Ardes D., Rossi I., Vezzani F., Spanevello A., Cherubino F., Visca D., Contoli M., Papi A., Morandi L., Battistini N., Luigi Moreo G., Iannuzzi P., Fumagalli D., Leone S., Oud J. A., Baysan M., Wigb J., van Heurn L. J., ter Haar S. B., Toppenberg A. G. L., Heerdink L., van IJlzinga Veenstra A. A., Eikenboom A. M., Wubbolts J., Uzorka J., Lijferink W., Meier R., de Jonge I. -B., Arbous S. M., de Boer M. G. J., van der Bom J. G., Dekkers O. M., Hassan, S, Ramspek, C, Ferrari, B, van Diepen, M, Rossio, R, Knevel, R, la Mura, V, Artoni, A, Martinelli, I, Bandera, A, Nobili, A, Gori, A, Blasi, F, Canetta, C, Montano, N, Rosendaal, F, Peyvandi, F, Bosari, S, Scudeller, L, Fusetti, G, Rusconi, L, Dell'Orto, S, Prati, D, Valenti, L, Giovannelli, S, Manunta, M, Lamorte, G, Ferarri, F, Muscatello, A, Mangioni, D, Alagna, L, Bozzi, G, Lombardi, A, Ungaro, R, Ancona, G, Zuglian, G, Bolis, M, Iannotti, N, Ludovisi, S, Comelli, A, Renisi, G, Biscarini, S, Castelli, V, Palomba, E, Fava, M, Fortina, V, Peri, C, Saltini, P, Viero, G, Itri, T, Ferroni, V, Pastore, V, Massafra, R, Liparoti, A, Muheberimana, T, Giommi, A, Bianco, R, De Azevedo, R, Chitani, G, Gualtierotti, R, Boasi, N, Pagliaro, E, Massimo, C, De Caro, M, Giachi, A, Vigone, B, Bellocchi, C, Carandina, A, Fiorelli, E, Melli, V, Tobaldini, E, Aliberti, S, Spotti, M, Terranova, L, Misuraca, S, D'Adda, A, Fiore, S, Di Pasquale, M, Mantero, M, Contarini, M, Ori, M, Morlacchi, L, Rossetti, V, Gramegna, A, Pappalettera, M, Cavallini, M, Buscemi, A, Vicenzi, M, Rota, I, Costantino, G, Solbiati, M, Furlan, L, Mancarella, M, Colombo, G, Fanin, A, Passarella, M, Monzani, V, Rovellini, A, Barbetta, L, Billi, F, Folli, C, Accordino, S, Maira, D, Hu, C, Motta, I, Scar-Amellini, N, Fracanzani, A, Lombardi, R, Cespiati, A, Cesari, M, Lucchi, T, Proietti, M, Calcaterra, L, Mandelli, C, Coppola, C, Cerizza, A, Maria Pesenti, A, Grasselli, G, Galazzi, A, Tet-Tamanti, M, Monti, I, Galbussera, A, Crisafulli, E, Girelli, D, Maroccia, A, Gabbiani, D, Busti, F, Vianello, A, Biondan, M, Sartori, F, Faverio, P, Pesci, A, Zucchetti, S, Bonfanti, P, Rossi, M, Beretta, I, Spolti, A, Harari, S, Elia, D, Cassandro, R, Caminati, A, Cipollone, F, Guagnano, M, D'Ardes, D, Rossi, I, Vezzani, F, Spanevello, A, Cherubino, F, Visca, D, Contoli, M, Papi, A, Morandi, L, Battistini, N, Luigi Moreo, G, Iannuzzi, P, Fumagalli, D, Leone, S, Oud, J, Baysan, M, Wigb, J, van Heurn, L, ter Haar, S, Toppenberg, A, Heerdink, L, van IJlzinga Veenstra, A, Eikenboom, A, Wubbolts, J, Uzorka, J, Lijferink, W, Meier, R, de Jonge, I, Arbous, S, de Boer, M, van der Bom, J, Dekkers, O, Hassan S., Ramspek C. L., Ferrari B., van Diepen M., Rossio R., Knevel R., la Mura V., Artoni A., Martinelli I., Bandera A., Nobili A., Gori A., Blasi F., Canetta C., Montano N., Rosendaal F. R., Peyvandi F., Bosari S., Scudeller L., Fusetti G., Rusconi L., Dell'Orto S., Prati D., Valenti L., Giovannelli S., Manunta M., Lamorte G., Ferarri F., Muscatello A., Mangioni D., Alagna L., Bozzi G., Lombardi A., Ungaro R., Ancona G., Zuglian G., Bolis M., Iannotti N., Ludovisi S., Comelli A., Renisi G., Biscarini S., Castelli V., Palomba E., Fava M., Fortina V., Peri C. A., Saltini P., Viero G., Itri T., Ferroni V., Pastore V., Massafra R., Liparoti A., Muheberimana T., Giommi A., Bianco R., De Azevedo R. M., Chitani G. E., Gualtierotti R., Boasi N., Pagliaro E., Massimo C., De Caro M., Giachi A., Vigone B., Bellocchi C., Carandina A., Fiorelli E., Melli V., Tobaldini E., Aliberti S., Spotti M., Terranova L., Misuraca S., D'Adda A., Fiore S. D., Di Pasquale M., Mantero M., Contarini M., Ori M., Morlacchi L., Rossetti V., Gramegna A., Pappalettera M., Cavallini M., Buscemi A., Vicenzi M., Rota I., Costantino G., Solbiati M., Furlan L., Mancarella M., Colombo G., Fanin A., Passarella M., Monzani V., Rovellini A., Barbetta L., Billi F., Folli C., Accordino S., Maira D., Hu C. M., Motta I., Scar-Amellini N., Fracanzani A. L., Lombardi R., Cespiati A., Cesari M., Lucchi T., Proietti M., Calcaterra L., Mandelli C., Coppola C., Cerizza A., Maria Pesenti A., Grasselli G., Galazzi A., Tet-Tamanti M., Monti I., Galbussera A. A., Crisafulli E., Girelli D., Maroccia A., Gabbiani D., Busti F., Vianello A., Biondan M., Sartori F., Faverio P., Pesci A., Zucchetti S., Bonfanti P., Rossi M., Beretta I., Spolti A., Harari S., Elia D., Cassandro R., Caminati A., Cipollone F., Guagnano M. T., D'Ardes D., Rossi I., Vezzani F., Spanevello A., Cherubino F., Visca D., Contoli M., Papi A., Morandi L., Battistini N., Luigi Moreo G., Iannuzzi P., Fumagalli D., Leone S., Oud J. A., Baysan M., Wigb J., van Heurn L. J., ter Haar S. B., Toppenberg A. G. L., Heerdink L., van IJlzinga Veenstra A. A., Eikenboom A. M., Wubbolts J., Uzorka J., Lijferink W., Meier R., de Jonge I. -B., Arbous S. M., de Boer M. G. J., van der Bom J. G., and Dekkers O. M.
Abstract: Background: The coronavirus disease 2019 (COVID-19) presents an urgent threat to global health. Prediction models that accurately estimate mortality risk in hospitalized patients could assist medical staff in treatment and allocating limited resources. Aims: To externally validate two promising previously published risk scores that predict in-hospital mortality among hospitalized COVID-19 patients. Methods: Two prospective cohorts were available; a cohort of 1028 patients admitted to one of nine hospitals in Lombardy, Italy (the Lombardy cohort) and a cohort of 432 patients admitted to a hospital in Leiden, the Netherlands (the Leiden cohort). The endpoint was in-hospital mortality. All patients were adult and tested COVID-19 PCR-positive. Model discrimination and calibration were assessed. Results: The C-statistic of the 4C mortality score was good in the Lombardy cohort (0.85, 95CI: 0.82−0.89) and in the Leiden cohort (0.87, 95CI: 0.80−0.94). Model calibration was acceptable in the Lombardy cohort but poor in the Leiden cohort due to the model systematically overpredicting the mortality risk for all patients. The C-statistic of the CURB-65 score was good in the Lombardy cohort (0.80, 95CI: 0.75−0.85) and in the Leiden cohort (0.82, 95CI: 0.76−0.88). The mortality rate in the CURB-65 development cohort was much lower than the mortality rate in the Lombardy cohort. A similar but less pronounced trend was found for patients in the Leiden cohort. Conclusion: Although performances did not differ greatly, the 4C mortality score showed the best performance. However, because of quickly changing circumstances, model recalibration may be necessary before using the 4C mortality score.
Published: 2022

29. Clinical factors associated with death in 3044 COVID-19 patients managed in internal medicine wards in Italy: comment

Author: Bandera, A, Nobili, A, Tettamanti, M, Harari, S, Bosari, S, Mannucci, P, Scudeller, L, Fusetti, G, Rusconi, L, Dell'Orto, S, Prati, D, Valenti, L, Giovannelli, S, Manunta, M, Lamorte, G, Ferrari, F, Gori, A, Muscatello, A, Mangioni, D, Alagna, L, Bozzi, G, Lombardi, A, Ungaro, R, Ancona, G, Zuglian, G, Bolis, M, Iannotti, N, Ludovisi, S, Comelli, A, Renisi, G, Biscarini, S, Castelli, V, Palomba, E, Fava, M, Fortina, V, Peri, C, Saltini, P, Viero, G, Itri, T, Ferroni, V, Pastore, V, Massafra, R, Liparoti, A, Muheberimana, T, Giommi, A, Bianco, R, De Azevedo, R, Chitani, G, Peyvandi, F, Gualtierotti, R, Ferrari, B, Rossio, R, Boasi, N, Pagliaro, E, Massimo, C, De Caro, M, Montano, N, Vigone, B, Bellocchi, C, Carandina, A, Fiorelli, E, Melli, V, Tobaldini, E, Blasi, F, Aliberti, S, Spotti, M, Terranova, L, Misuraca, S, D'Adda, A, Della Fiore, S, Di Pasquale, M, Contarini, M, Ori, M, Morlacchi, L, Rossetti, V, Gramegna, A, Pappalettera, M, Cavallini, M, Buscemi, A, Vicenzi, M, Rota, I, Costantino, G, Solbiati, M, Furlan, L, Mancarella, M, Colombo, G, Fanin, A, Passarella, M, Monzani, V, Canetta, C, Rovellini, A, Barbetta, L, Billi, F, Folli, C, Accordino, S, Maira, D, Hu, C, Motta, I, Scaramellini, N, Fracanzani, A, Lombardi, R, Cespiati, A, Cesari, M, Lucchi, T, Proietti, M, Calcaterra, L, Mandelli, C, Coppola, C, Cerizza, A, Pesenti, A, Grasselli, G, Galazzi, A, Monti, I, Galbussera, A, Crisafulli, E, Girelli, D, Maroccia, A, Gabbiani, D, Busti, F, Vianello, A, Biondan, M, Sartori, F, Faverio, P, Pesci, A, Zucchetti, S, Bonfanti, P, Rossi, M, Beretta, I, Spolti, A, Elia, D, Cassandro, R, Caminati, A, Cipollone, F, Guagnano, M, D'Ardes, D, Rossi, I, Vezzani, F, Spanevello, A, Cherubino, F, Visca, D, Contoli, M, Papi, A, Morandi, L, Battistini, N, Moreo, G, Iannuzzi, P, Fumagalli, D, Leone, S, Bandera A., Nobili A., Tettamanti M., Harari S., Bosari S., Mannucci P. M., Scudeller L., Fusetti G., Rusconi L., Dell'Orto S., Prati D., Valenti L., Giovannelli S., Manunta M., Lamorte G., Ferrari F., Gori A., Muscatello A., Mangioni D., Alagna L., Bozzi G., Lombardi A., Ungaro R., Ancona G., Zuglian G., Bolis M., Iannotti N., Ludovisi S., Comelli A., Renisi G., Biscarini S., Castelli V., Palomba E., Fava M., Fortina V., Peri C. A., Saltini P., Viero G., Itri T., Ferroni V., Pastore V., Massafra R., Liparoti A., Muheberimana T., Giommi A., Bianco R., De Azevedo R. M., Chitani G. E., Peyvandi F., Gualtierotti R., Ferrari B., Rossio R., Boasi N., Pagliaro E., Massimo C., De Caro M., Montano N., Vigone B., Bellocchi C., Carandina A., Fiorelli E., Melli V., Tobaldini E., Blasi F., Aliberti S., Spotti M., Terranova L., Misuraca S., D'Adda A., Della Fiore S., Di Pasquale M., Contarini M. M. M., Ori M., Morlacchi L., Rossetti V., Gramegna A., Pappalettera M., Cavallini M., Buscemi A., Vicenzi M., Rota I., Costantino G., Solbiati M., Furlan L., Mancarella M., Colombo G., Fanin A., Passarella M., Monzani V., Canetta C., Rovellini A., Barbetta L., Billi F., Folli C., Accordino S., Maira D., Hu C. M., Motta I., Scaramellini N., Fracanzani A. L., Lombardi R., Cespiati A., Cesari M., Lucchi T., Proietti M., Calcaterra L., Mandelli C., Coppola C., Cerizza A., Pesenti A. M., Grasselli G., Galazzi A., Monti I., Galbussera A. A., Crisafulli E., Girelli D., Maroccia A., Gabbiani D., Busti F., Vianello A., Biondan M., Sartori F., Faverio P., Pesci A., Zucchetti S., Bonfanti P., Rossi M., Beretta I., Spolti A., Elia D., Cassandro R., Caminati A., Cipollone F., Guagnano M. T., D'Ardes D., Rossi I., Vezzani F., Spanevello A., Cherubino F., Visca D., Contoli M., Papi A., Morandi L., Battistini N., Moreo G. L., Iannuzzi P., Fumagalli D., Leone S., Bandera, A, Nobili, A, Tettamanti, M, Harari, S, Bosari, S, Mannucci, P, Scudeller, L, Fusetti, G, Rusconi, L, Dell'Orto, S, Prati, D, Valenti, L, Giovannelli, S, Manunta, M, Lamorte, G, Ferrari, F, Gori, A, Muscatello, A, Mangioni, D, Alagna, L, Bozzi, G, Lombardi, A, Ungaro, R, Ancona, G, Zuglian, G, Bolis, M, Iannotti, N, Ludovisi, S, Comelli, A, Renisi, G, Biscarini, S, Castelli, V, Palomba, E, Fava, M, Fortina, V, Peri, C, Saltini, P, Viero, G, Itri, T, Ferroni, V, Pastore, V, Massafra, R, Liparoti, A, Muheberimana, T, Giommi, A, Bianco, R, De Azevedo, R, Chitani, G, Peyvandi, F, Gualtierotti, R, Ferrari, B, Rossio, R, Boasi, N, Pagliaro, E, Massimo, C, De Caro, M, Montano, N, Vigone, B, Bellocchi, C, Carandina, A, Fiorelli, E, Melli, V, Tobaldini, E, Blasi, F, Aliberti, S, Spotti, M, Terranova, L, Misuraca, S, D'Adda, A, Della Fiore, S, Di Pasquale, M, Contarini, M, Ori, M, Morlacchi, L, Rossetti, V, Gramegna, A, Pappalettera, M, Cavallini, M, Buscemi, A, Vicenzi, M, Rota, I, Costantino, G, Solbiati, M, Furlan, L, Mancarella, M, Colombo, G, Fanin, A, Passarella, M, Monzani, V, Canetta, C, Rovellini, A, Barbetta, L, Billi, F, Folli, C, Accordino, S, Maira, D, Hu, C, Motta, I, Scaramellini, N, Fracanzani, A, Lombardi, R, Cespiati, A, Cesari, M, Lucchi, T, Proietti, M, Calcaterra, L, Mandelli, C, Coppola, C, Cerizza, A, Pesenti, A, Grasselli, G, Galazzi, A, Monti, I, Galbussera, A, Crisafulli, E, Girelli, D, Maroccia, A, Gabbiani, D, Busti, F, Vianello, A, Biondan, M, Sartori, F, Faverio, P, Pesci, A, Zucchetti, S, Bonfanti, P, Rossi, M, Beretta, I, Spolti, A, Elia, D, Cassandro, R, Caminati, A, Cipollone, F, Guagnano, M, D'Ardes, D, Rossi, I, Vezzani, F, Spanevello, A, Cherubino, F, Visca, D, Contoli, M, Papi, A, Morandi, L, Battistini, N, Moreo, G, Iannuzzi, P, Fumagalli, D, Leone, S, Bandera A., Nobili A., Tettamanti M., Harari S., Bosari S., Mannucci P. M., Scudeller L., Fusetti G., Rusconi L., Dell'Orto S., Prati D., Valenti L., Giovannelli S., Manunta M., Lamorte G., Ferrari F., Gori A., Muscatello A., Mangioni D., Alagna L., Bozzi G., Lombardi A., Ungaro R., Ancona G., Zuglian G., Bolis M., Iannotti N., Ludovisi S., Comelli A., Renisi G., Biscarini S., Castelli V., Palomba E., Fava M., Fortina V., Peri C. A., Saltini P., Viero G., Itri T., Ferroni V., Pastore V., Massafra R., Liparoti A., Muheberimana T., Giommi A., Bianco R., De Azevedo R. M., Chitani G. E., Peyvandi F., Gualtierotti R., Ferrari B., Rossio R., Boasi N., Pagliaro E., Massimo C., De Caro M., Montano N., Vigone B., Bellocchi C., Carandina A., Fiorelli E., Melli V., Tobaldini E., Blasi F., Aliberti S., Spotti M., Terranova L., Misuraca S., D'Adda A., Della Fiore S., Di Pasquale M., Contarini M. M. M., Ori M., Morlacchi L., Rossetti V., Gramegna A., Pappalettera M., Cavallini M., Buscemi A., Vicenzi M., Rota I., Costantino G., Solbiati M., Furlan L., Mancarella M., Colombo G., Fanin A., Passarella M., Monzani V., Canetta C., Rovellini A., Barbetta L., Billi F., Folli C., Accordino S., Maira D., Hu C. M., Motta I., Scaramellini N., Fracanzani A. L., Lombardi R., Cespiati A., Cesari M., Lucchi T., Proietti M., Calcaterra L., Mandelli C., Coppola C., Cerizza A., Pesenti A. M., Grasselli G., Galazzi A., Monti I., Galbussera A. A., Crisafulli E., Girelli D., Maroccia A., Gabbiani D., Busti F., Vianello A., Biondan M., Sartori F., Faverio P., Pesci A., Zucchetti S., Bonfanti P., Rossi M., Beretta I., Spolti A., Elia D., Cassandro R., Caminati A., Cipollone F., Guagnano M. T., D'Ardes D., Rossi I., Vezzani F., Spanevello A., Cherubino F., Visca D., Contoli M., Papi A., Morandi L., Battistini N., Moreo G. L., Iannuzzi P., Fumagalli D., and Leone S.
Published: 2022

30. Clinical risk scores for the early prediction of severe outocomes in patients hospitalized for COVID-19: comment

Author: Rossio, R, Tettamanti, M, Nobili, A, Harari, S, Mannucci, P, Bandera, A, Peyvandi, F, Bosari, S, Scudeller, L, Fusetti, G, Rusconi, L, Dell'Orto, S, Prati, D, Valenti, L, Giovannelli, S, Manunta, M, Lamorte, G, Ferrari, F, Gori, A, Muscatello, A, Mangioni, D, Alagna, L, Bozzi, G, Lombardi, A, Ungaro, R, Ancona, G, Zuglian, G, Bolis, M, Iannotti, N, Ludovisi, S, Comelli, A, Renisi, G, Biscarini, S, Castelli, V, Palomba, E, Fava, M, Fortina, V, Peri, C, Saltini, P, Viero, G, Itri, T, Ferroni, V, Pastore, V, Massafra, R, Liparoti, A, Muheberimana, T, Giommi, A, Bianco, R, De Azevedo, R, Chitani, G, Gualtierotti, R, Ferrari, B, Boasi, N, Pagliaro, E, Massimo, C, De Caro, M, Giachi, A, Montano, N, Vigone, B, Bellocchi, C, Carandina, A, Fiorelli, E, Melli, V, Tobaldini, E, Blasi, F, Aliberti, S, Spotti, M, Terranova, L, Misuraca, S, D'Adda, A, Fiore, S, Di Pasquale, M, Mantero, M, Contarini, M, Ori, M, Morlacchi, L, Rossetti, V, Gramegna, A, Pappalettera, M, Cavallini, M, Buscemi, A, Vicenzi, M, Rota, I, Costantino, G, Solbiati, M, Furlan, L, Mancarella, M, Colombo, G, Fanin, A, Passarella, M, Monzani, V, Canetta, C, Rovellini, A, Barbetta, L, Billi, F, Folli, C, Accordino, S, Maira, D, Hu, C, Motta, I, Scaramellini, N, Fracanzani, A, Lombardi, R, Cespiati, A, Cesari, M, Lucchi, T, Proietti, M, Calcaterra, L, Mandelli, C, Coppola, C, Cerizza, A, Pesenti, A, Grasselli, G, Galazzi, A, Monti, I, Galbussera, A, Crisafulli, E, Girelli, D, Maroccia, A, Gabbiani, D, Busti, F, Vianello, A, Biondan, M, Sartori, F, Faverio, P, Pesci, A, Zucchetti, S, Bonfanti, P, Rossi, M, Beretta, I, Spolti, A, Elia, D, Cassandro, R, Caminati, A, Cipollone, F, Guagnano, M, D'Ardes, D, Rossi, I, Vezzani, F, Spanevello, A, Cherubino, F, Visca, D, Contoli, M, Papi, A, Morandi, L, Battistini, N, Moreo, G, Iannuzzi, P, Fumagalli, D, Leone, S, Rossio R., Tettamanti M., Nobili A., Harari S., Mannucci P. M., Bandera A., Peyvandi F., Bosari S., Scudeller L., Fusetti G., Rusconi L., Dell'Orto S., Prati D., Valenti L., Giovannelli S., Manunta M., Lamorte G., Ferrari F., Gori A., Muscatello A., Mangioni D., Alagna L., Bozzi G., Lombardi A., Ungaro R., Ancona G., Zuglian G., Bolis M., Iannotti N., Ludovisi S., Comelli A., Renisi G., Biscarini S., Castelli V., Palomba E., Fava M., Fortina V., Peri C. A., Saltini P., Viero G., Itri T., Ferroni V., Pastore V., Massafra R., Liparoti A., Muheberimana T., Giommi A., Bianco R., De Azevedo R. M., Chitani G. E., Gualtierotti R., Ferrari B., Boasi N., Pagliaro E., Massimo C., De Caro M., Giachi A., Montano N., Vigone B., Bellocchi C., Carandina A., Fiorelli E., Melli V., Tobaldini E., Blasi F., Aliberti S., Spotti M., Terranova L., Misuraca S., D'Adda A., Fiore S. D., Di Pasquale M., Mantero M., Contarini M., Ori M., Morlacchi L., Rossetti V., Gramegna A., Pappalettera M., Cavallini M., Buscemi A., Vicenzi M., Rota I., Costantino G., Solbiati M., Furlan L., Mancarella M., Colombo G., Fanin A., Passarella M., Monzani V., Canetta C., Rovellini A., Barbetta L., Billi F., Folli C., Accordino S., Maira D., Hu C. M., Motta I., Scaramellini N., Fracanzani A. L., Lombardi R., Cespiati A., Cesari M., Lucchi T., Proietti M., Calcaterra L., Mandelli C., Coppola C., Cerizza A., Pesenti A. M., Grasselli G., Galazzi A., Monti I., Galbussera A. A., Crisafulli E., Girelli D., Maroccia A., Gabbiani D., Busti F., Vianello A., Biondan M., Sartori F., Faverio P., Pesci A., Zucchetti S., Bonfanti P., Rossi M., Beretta I., Spolti A., Elia D., Cassandro R., Caminati A., Cipollone F., Guagnano M. T., D'Ardes D., Rossi I., Vezzani F., Spanevello A., Cherubino F., Visca D., Contoli M., Papi A., Morandi L., Battistini N., Moreo G. L., Iannuzzi P., Fumagalli D., Leone S., Rossio, R, Tettamanti, M, Nobili, A, Harari, S, Mannucci, P, Bandera, A, Peyvandi, F, Bosari, S, Scudeller, L, Fusetti, G, Rusconi, L, Dell'Orto, S, Prati, D, Valenti, L, Giovannelli, S, Manunta, M, Lamorte, G, Ferrari, F, Gori, A, Muscatello, A, Mangioni, D, Alagna, L, Bozzi, G, Lombardi, A, Ungaro, R, Ancona, G, Zuglian, G, Bolis, M, Iannotti, N, Ludovisi, S, Comelli, A, Renisi, G, Biscarini, S, Castelli, V, Palomba, E, Fava, M, Fortina, V, Peri, C, Saltini, P, Viero, G, Itri, T, Ferroni, V, Pastore, V, Massafra, R, Liparoti, A, Muheberimana, T, Giommi, A, Bianco, R, De Azevedo, R, Chitani, G, Gualtierotti, R, Ferrari, B, Boasi, N, Pagliaro, E, Massimo, C, De Caro, M, Giachi, A, Montano, N, Vigone, B, Bellocchi, C, Carandina, A, Fiorelli, E, Melli, V, Tobaldini, E, Blasi, F, Aliberti, S, Spotti, M, Terranova, L, Misuraca, S, D'Adda, A, Fiore, S, Di Pasquale, M, Mantero, M, Contarini, M, Ori, M, Morlacchi, L, Rossetti, V, Gramegna, A, Pappalettera, M, Cavallini, M, Buscemi, A, Vicenzi, M, Rota, I, Costantino, G, Solbiati, M, Furlan, L, Mancarella, M, Colombo, G, Fanin, A, Passarella, M, Monzani, V, Canetta, C, Rovellini, A, Barbetta, L, Billi, F, Folli, C, Accordino, S, Maira, D, Hu, C, Motta, I, Scaramellini, N, Fracanzani, A, Lombardi, R, Cespiati, A, Cesari, M, Lucchi, T, Proietti, M, Calcaterra, L, Mandelli, C, Coppola, C, Cerizza, A, Pesenti, A, Grasselli, G, Galazzi, A, Monti, I, Galbussera, A, Crisafulli, E, Girelli, D, Maroccia, A, Gabbiani, D, Busti, F, Vianello, A, Biondan, M, Sartori, F, Faverio, P, Pesci, A, Zucchetti, S, Bonfanti, P, Rossi, M, Beretta, I, Spolti, A, Elia, D, Cassandro, R, Caminati, A, Cipollone, F, Guagnano, M, D'Ardes, D, Rossi, I, Vezzani, F, Spanevello, A, Cherubino, F, Visca, D, Contoli, M, Papi, A, Morandi, L, Battistini, N, Moreo, G, Iannuzzi, P, Fumagalli, D, Leone, S, Rossio R., Tettamanti M., Nobili A., Harari S., Mannucci P. M., Bandera A., Peyvandi F., Bosari S., Scudeller L., Fusetti G., Rusconi L., Dell'Orto S., Prati D., Valenti L., Giovannelli S., Manunta M., Lamorte G., Ferrari F., Gori A., Muscatello A., Mangioni D., Alagna L., Bozzi G., Lombardi A., Ungaro R., Ancona G., Zuglian G., Bolis M., Iannotti N., Ludovisi S., Comelli A., Renisi G., Biscarini S., Castelli V., Palomba E., Fava M., Fortina V., Peri C. A., Saltini P., Viero G., Itri T., Ferroni V., Pastore V., Massafra R., Liparoti A., Muheberimana T., Giommi A., Bianco R., De Azevedo R. M., Chitani G. E., Gualtierotti R., Ferrari B., Boasi N., Pagliaro E., Massimo C., De Caro M., Giachi A., Montano N., Vigone B., Bellocchi C., Carandina A., Fiorelli E., Melli V., Tobaldini E., Blasi F., Aliberti S., Spotti M., Terranova L., Misuraca S., D'Adda A., Fiore S. D., Di Pasquale M., Mantero M., Contarini M., Ori M., Morlacchi L., Rossetti V., Gramegna A., Pappalettera M., Cavallini M., Buscemi A., Vicenzi M., Rota I., Costantino G., Solbiati M., Furlan L., Mancarella M., Colombo G., Fanin A., Passarella M., Monzani V., Canetta C., Rovellini A., Barbetta L., Billi F., Folli C., Accordino S., Maira D., Hu C. M., Motta I., Scaramellini N., Fracanzani A. L., Lombardi R., Cespiati A., Cesari M., Lucchi T., Proietti M., Calcaterra L., Mandelli C., Coppola C., Cerizza A., Pesenti A. M., Grasselli G., Galazzi A., Monti I., Galbussera A. A., Crisafulli E., Girelli D., Maroccia A., Gabbiani D., Busti F., Vianello A., Biondan M., Sartori F., Faverio P., Pesci A., Zucchetti S., Bonfanti P., Rossi M., Beretta I., Spolti A., Elia D., Cassandro R., Caminati A., Cipollone F., Guagnano M. T., D'Ardes D., Rossi I., Vezzani F., Spanevello A., Cherubino F., Visca D., Contoli M., Papi A., Morandi L., Battistini N., Moreo G. L., Iannuzzi P., Fumagalli D., and Leone S.
Published: 2022

31. Charging of free-falling test masses in orbit due to cosmic rays: Results from LISA Pathfinder

Author: Armano, M., primary, Audley, H., additional, Baird, J., additional, Binetruy, P., additional, Born, M., additional, Bortoluzzi, D., additional, Castelli, E., additional, Cavalleri, A., additional, Cesarini, A., additional, Cruise, A. M., additional, Danzmann, K., additional, de Deus Silva, M., additional, Diepholz, I., additional, Dixon, G., additional, Dolesi, R., additional, Ferraioli, L., additional, Ferroni, V., additional, Fitzsimons, E. D., additional, Freschi, M., additional, Gesa, L., additional, Giardini, D., additional, Gibert, F., additional, Giusteri, R., additional, Grimani, C., additional, Grzymisch, J., additional, Harrison, I., additional, Hartig, M.-S., additional, Heinzel, G., additional, Hewitson, M., additional, Hollington, D., additional, Hoyland, D., additional, Hueller, M., additional, Inchauspé, H., additional, Jennrich, O., additional, Jetzer, P., additional, Karnesis, N., additional, Kaune, B., additional, Killow, C. J., additional, Korsakova, N., additional, Lobo, J. A., additional, López-Zaragoza, J. P., additional, Maarschalkerweerd, R., additional, Mance, D., additional, Martín, V., additional, Martino, J., additional, Martin-Polo, L., additional, Martin-Porqueras, F., additional, McNamara, P. W., additional, Mendes, J., additional, Mendes, L., additional, Meshksar, N., additional, Nofrarias, M., additional, Paczkowski, S., additional, Perreur-Lloyd, M., additional, Petiteau, A., additional, Plagnol, E., additional, Ramos-Castro, J., additional, Reiche, J., additional, Rivas, F., additional, Robertson, D. I., additional, Russano, G., additional, Slutsky, J., additional, Sopuerta, C. F., additional, Sumner, T. J., additional, Texier, D., additional, Thorpe, J. I., additional, Vetrugno, D., additional, Vitale, S., additional, Wanner, G., additional, Ward, H., additional, Wass, P. J., additional, Weber, W. J., additional, Wissel, L., additional, Wittchen, A., additional, and Zweifel, P., additional
Published: 2023
Full Text: View/download PDF

32. Charging of free-falling test masses in orbit due to cosmic rays: Results from LISA Pathfinder

Author: Armano, M., Audley, H., Baird, J., Binetruy, P., Born, M., Bortoluzzi, D., Castelli, E., Cavalleri, A., Cesarini, A., Cruise, A.M., Danzmann, K., De Deus, Silva M., Diepholz, I., Dixon, G., Dolesi, R., Ferraioli, L., Ferroni, V., Fitzsimons, E.D., Freschi, M., Gesa, L., Giardini, D., Gibert, F., Giusteri, R., Grimani, C., Grzymisch, J., Harrison, I., Hartig, M.-S., Heinzel, G., Hewitson, M., Hollington, D., Hoyland, D., Hueller, M., Inchauspé, H., Jennrich, O., Jetzer, P., Karnesis, N., Kaune, B., Killow, C.J., Korsakova, N., Lobo, J.A., López-Zaragoza, J.P., Maarschalkerweerd, R., Mance, D., Martín, V., Martino, J., Martin-Polo, L., Martin-Porqueras, F., McNamara, P.W., Mendes, J., Mendes, L., Meshksar, N., Nofrarias, M., Paczkowski, S., Perreur-Lloyd, M., Petiteau, A., Plagnol, E., Ramos-Castro, J., Reiche, J., Rivas, F., Robertson, D.I., Russano, G., Slutsky, J., Sopuerta, C.F., Sumner, T.J., Texier, D., Thorpe, J.I., Vetrugno, D., Vitale, S., Wanner, G., Ward, H., Wass, P.J., Weber, W.J., Wissel, L., Wittchen, A., Zweifel, P., Armano, M., Audley, H., Baird, J., Binetruy, P., Born, M., Bortoluzzi, D., Castelli, E., Cavalleri, A., Cesarini, A., Cruise, A.M., Danzmann, K., De Deus, Silva M., Diepholz, I., Dixon, G., Dolesi, R., Ferraioli, L., Ferroni, V., Fitzsimons, E.D., Freschi, M., Gesa, L., Giardini, D., Gibert, F., Giusteri, R., Grimani, C., Grzymisch, J., Harrison, I., Hartig, M.-S., Heinzel, G., Hewitson, M., Hollington, D., Hoyland, D., Hueller, M., Inchauspé, H., Jennrich, O., Jetzer, P., Karnesis, N., Kaune, B., Killow, C.J., Korsakova, N., Lobo, J.A., López-Zaragoza, J.P., Maarschalkerweerd, R., Mance, D., Martín, V., Martino, J., Martin-Polo, L., Martin-Porqueras, F., McNamara, P.W., Mendes, J., Mendes, L., Meshksar, N., Nofrarias, M., Paczkowski, S., Perreur-Lloyd, M., Petiteau, A., Plagnol, E., Ramos-Castro, J., Reiche, J., Rivas, F., Robertson, D.I., Russano, G., Slutsky, J., Sopuerta, C.F., Sumner, T.J., Texier, D., Thorpe, J.I., Vetrugno, D., Vitale, S., Wanner, G., Ward, H., Wass, P.J., Weber, W.J., Wissel, L., Wittchen, A., and Zweifel, P.
Abstract: A comprehensive summary of the measurements made to characterize test-mass charging due to the space environment during the LISA Pathfinder mission is presented. Measurements of the residual charge of the test mass after release by the grabbing and positioning mechanism show that the initial charge of the test masses was negative after all releases, leaving the test mass with a potential in the range from -12 to -512. Variations in the neutral test-mass charging rate between 21.7 and 30.7 e s-1 were observed over the course of the 17-month science operations produced by cosmic ray flux changes including a Forbush decrease associated with a small solar energetic particle event. A dependence of the cosmic ray charging rate on the test-mass potential between -30.2 and -40.3 e s-1 V-1 was observed resulting in an equilibrium test-mass potential between 670 and 960 mV, and this is attributed to a contribution to charging from low-energy electrons emitted from the gold surfaces of the gravitational reference sensor. Data from the onboard particle detector show a reliable correlation with the charging rate and with other environmental monitors of the cosmic ray flux. This correlation is exploited to extrapolate test-mass charging rates to a 20-year period giving useful insight into the expected range of charging rate that may be observed in the LISA mission.
Published: 2023

33. Charging of free-falling test masses in orbit due to cosmic rays: Results from LISA Pathfinder

Author: Armano, M, Audley, H, Baird, J, Jetzer, Philippe, Born, M, Bortoluzzi, D, Castelli, E, Cavalleri, A, Cesarini, A, Cruise, A M, Danzmann, K, de Deus Silva, M, Diepholz, I, Dixon, G, Dolesi, R, Ferraioli, L, Ferroni, V, Fitzsimons, E D, Freschi, M, Gesa, L, Giardini, D, Gibert, F, Giusteri, R, Grimani, C, Grzymisch, J, Harrison, I, Hartig, M-S; https://orcid.org/0000-0002-1078-3497, Heinzel, G, Hewitson, M, Hollington, D, et al, Armano, M, Audley, H, Baird, J, Jetzer, Philippe, Born, M, Bortoluzzi, D, Castelli, E, Cavalleri, A, Cesarini, A, Cruise, A M, Danzmann, K, de Deus Silva, M, Diepholz, I, Dixon, G, Dolesi, R, Ferraioli, L, Ferroni, V, Fitzsimons, E D, Freschi, M, Gesa, L, Giardini, D, Gibert, F, Giusteri, R, Grimani, C, Grzymisch, J, Harrison, I, Hartig, M-S; https://orcid.org/0000-0002-1078-3497, Heinzel, G, Hewitson, M, Hollington, D, and et al
Abstract: A comprehensive summary of the measurements made to characterize test-mass charging due to the space environment during the LISA Pathfinder mission is presented. Measurements of the residual charge of the test mass after release by the grabbing and positioning mechanism show that the initial charge of the test masses was negative after all releases, leaving the test mass with a potential in the range from −12 to −512. Variations in the neutral test-mass charging rate between 21.7 and 30.7 e s$^{−1}$ were observed over the course of the 17-month science operations produced by cosmic ray flux changes including a Forbush decrease associated with a small solar energetic particle event. A dependence of the cosmic ray charging rate on the test-mass potential between −30.2 and −40.3 e s$^{−1}$ V$^{−1}$ was observed resulting in an equilibrium test-mass potential between 670 and 960 mV, and this is attributed to a contribution to charging from low-energy electrons emitted from the gold surfaces of the gravitational reference sensor. Data from the onboard particle detector show a reliable correlation with the charging rate and with other environmental monitors of the cosmic ray flux. This correlation is exploited to extrapolate test-mass charging rates to a 20-year period giving useful insight into the expected range of charging rate that may be observed in the LISA mission.
Published: 2023

34. Tilt-to-length coupling in LISA Pathfinder: A data analysis

Author: Jetzer, P, Audley, H, Baird, J, Binetruy, P, Born, M, Bortoluzzi, D, Castelli, E, Cavalleri, A, Cesarini, A, Cruise, A M, Danzmann, K, de Deus Silva, M, Diepholz, I, Dixon, G, Dolesi, R, Ferraioli, L, Ferroni, V, Fitzsimons, E D, Freschi, M, Gesa, L, Giardini, D, Gibert, F, Giusteri, R, Grimani, C, Grzymisch, J, Harrison, I, Hartig, M-S; https://orcid.org/0000-0002-1078-3497, Heinzel, G, Hewitson, M, Hollington, D, et al, Jetzer, P, Audley, H, Baird, J, Binetruy, P, Born, M, Bortoluzzi, D, Castelli, E, Cavalleri, A, Cesarini, A, Cruise, A M, Danzmann, K, de Deus Silva, M, Diepholz, I, Dixon, G, Dolesi, R, Ferraioli, L, Ferroni, V, Fitzsimons, E D, Freschi, M, Gesa, L, Giardini, D, Gibert, F, Giusteri, R, Grimani, C, Grzymisch, J, Harrison, I, Hartig, M-S; https://orcid.org/0000-0002-1078-3497, Heinzel, G, Hewitson, M, Hollington, D, and et al
Abstract: We present a study of the tilt-to-length coupling noise during the LISA Pathfinder mission and how it depended on the system’s alignment. Tilt-to-length coupling noise is the unwanted coupling of angular and lateral spacecraft or test mass motion into the primary interferometric displacement readout. It was one of the major noise sources in the LISA Pathfinder mission and is likewise expected to be a primary noise source in LISA. We demonstrate here that a recently derived and published analytical model describes the dependency of the LISA Pathfinder tilt-to-length coupling noise on the alignment of the two freely falling test masses. This was verified with the data taken before and after the realignments performed in March (engineering days) and June 2016, and during a two-day experiment in February 2017 (long cross-talk experiment). The latter was performed with the explicit goal of testing the tilt-to-length coupling noise dependency on the test mass alignment. Using the analytical model, we show that all realignments performed during the mission were only partially successful and explain the reasons why. In addition to the analytical model, we computed another physical tilt-to-length coupling model via a minimizing routine making use of the long cross-talk experiment data. A similar approach could prove useful for the LISA mission.
Published: 2023

35. Dark gravitomagnetism with LISA and gravitational waves space detectors

Author: Tartaglia, A., primary, Bassan, M., additional, Pucacco, G., additional, Ferroni, V., additional, and Vetrugno, D., additional
Published: 2023
Full Text: View/download PDF

36. Sensor noise in LISA Pathfinder: An extensive in-flight review of the angular and longitudinal interferometric measurement system

Author: Jetzer, P, Tiwari, S, Lopez, D, Haney, M, Ebersold, M, Boitier, A, Hamilton, E, Xu, Y, Cavalleri, A, Cesarini, A, Cruise, A M, Danzmann, K, de Deus Silva, M, Diepholz, I, Dixon, G, Dolesi, R, Ferraioli, L, Ferroni, V, Fitzsimons, E D, Flatscher, R, Freschi, M, García, A, Gerndt, R, Gesa, L, Giardini, D, Gibert, F, Giusteri, R, Grimani, C, Grzymisch, J, Guzman, F, et al, and University of Zurich
Subjects: 530 Physics, 10192 Physics Institute
Published: 2022

37. Transient acceleration events in LISA Pathfinder data: Properties and possible physical origin

Author: Jetzer, P, Tiwari, S, Lopez, D, Haney, M, Ebersold, M, Boitier, A, Hamilton, Eleanor Z, Xu, Y, Cesarini, A, Chiavegato, V, Cruise, A M, Dal Bosco, D, Danzmann, K, De Deus Silva, M, Diepholz, I, Dixon, G, Dolesi, R, Ferraioli, L, Ferroni, V, Fitzsimons, E D, Freschi, M, Gesa, L, Giardini, D, Gibert, F, Giusteri, R, Grimani, C, Grzymisch, J, Harrison, I, Hartig, M S, Heinzel, G, et al, and University of Zurich
Subjects: 530 Physics, 10192 Physics Institute, 3106 Nuclear and High Energy Physics
Published: 2022

38. Sensor noise in LISA Pathfinder : An extensive in-flight review of the angular and longitudinal interferometric measurement system

Author: Armano, M., primary, Audley, H., additional, Baird, J., additional, Binetruy, P., additional, Born, M., additional, Bortoluzzi, D., additional, Brandt, N., additional, Castelli, E., additional, Cavalleri, A., additional, Cesarini, A., additional, Cruise, A. M., additional, Danzmann, K., additional, de Deus Silva, M., additional, Diepholz, I., additional, Dixon, G., additional, Dolesi, R., additional, Ferraioli, L., additional, Ferroni, V., additional, Fitzsimons, E. D., additional, Flatscher, R., additional, Freschi, M., additional, García, A., additional, Gerndt, R., additional, Gesa, L., additional, Giardini, D., additional, Gibert, F., additional, Giusteri, R., additional, Grimani, C., additional, Grzymisch, J., additional, Guzman, F., additional, Harrison, I., additional, Hartig, M-S, additional, Hechenblaikner, G., additional, Heinzel, G., additional, Hewitson, M., additional, Hollington, D., additional, Hoyland, D., additional, Hueller, M., additional, Inchauspé, H., additional, Jennrich, O., additional, Jetzer, P., additional, Johann, U., additional, Johlander, B., additional, Karnesis, N., additional, Kaune, B., additional, Killow, C. J., additional, Korsakova, N., additional, Lobo, J. A., additional, López-Zaragoza, J. P., additional, Maarschalkerweerd, R., additional, Mance, D., additional, Martín, V., additional, Martin-Polo, L., additional, Martin-Porqueras, F., additional, Martino, J., additional, McNamara, P. W., additional, Mendes, J., additional, Mendes, L., additional, Meshksar, N., additional, Monsky, A., additional, Nofrarias, M., additional, Paczkowski, S., additional, Perreur-Lloyd, M., additional, Petiteau, A., additional, Plagnol, E., additional, Ramos-Castro, J., additional, Reiche, J., additional, Rivas, F., additional, Robertson, D. I., additional, Russano, G., additional, Sanjuan, J., additional, Slutsky, J., additional, Sopuerta, C. F., additional, Steier, F., additional, Sumner, T., additional, Texier, D., additional, Thorpe, J. I., additional, Vetrugno, D., additional, Vitale, S., additional, Wand, V., additional, Wanner, G., additional, Ward, H., additional, Wass, P. J., additional, Weber, W. J., additional, Wissel, L., additional, Wittchen, A., additional, and Zweifel, P., additional
Published: 2022
Full Text: View/download PDF

39. Detecting gravitomagnetism with space-based gravitational wave observatories

Author: Tartaglia, A, primary, Bassan, M, additional, Pucacco, G, additional, Ferroni, V, additional, and Vetrugno, D, additional
Published: 2022
Full Text: View/download PDF

40. Adjuvant surgical treatment of non-tuberculous mycobacterial lung disease in chronic thromboembolic pulmonary hypertension: A first case report

Author: Bertuccio, F.R., Baio, N., Montini, S., Ferroni, V., Chino, V., Pisanu, L., Russo, M., Giana, I., Cascina, A., Conio, V., Primiceri, C., Stella, G.M., and Corsico, A.G.
Published: 2024
Full Text: View/download PDF

41. Clinical factors associated with death in 3044 COVID-19 patients managed in internal medicine wards in Italy: comment

Author: Bandera, A., Nobili, A., Tettamanti, M., Harari, S., Bosari, S., Mannucci, P. M., Scudeller, L., Fusetti, G., Rusconi, L., Dell'Orto, S., Prati, D., Valenti, L., Giovannelli, S., Manunta, M., Lamorte, G., Ferrari, F., Gori, A., Muscatello, A., Mangioni, D., Alagna, L., Bozzi, G., Lombardi, A., Ungaro, R., Ancona, G., Zuglian, G., Bolis, M., Iannotti, N., Ludovisi, S., Comelli, A., Renisi, G., Biscarini, S., Castelli, V., Palomba, E., Fava, M., Fortina, V., Peri, C. A., Saltini, P., Viero, G., Itri, T., Ferroni, V., Pastore, V., Massafra, R., Liparoti, A., Muheberimana, T., Giommi, A., Bianco, R., De Azevedo, R. M., Chitani, G. E., Peyvandi, F., Gualtierotti, R., Ferrari, B., Rossio, R., Boasi, N., Pagliaro, E., Massimo, C., De Caro, M., Montano, N., Vigone, B., Bellocchi, C., Carandina, A., Fiorelli, E., Melli, V., Tobaldini, E., Blasi, F., Aliberti, S., Spotti, M., Terranova, L., Misuraca, S., D'Adda, A., Della Fiore, S., Di Pasquale, M., Contarini, M. M. M., Ori, M., Morlacchi, L., Rossetti, V., Gramegna, A., Pappalettera, M., Cavallini, M., Buscemi, A., Vicenzi, M., Rota, I., Costantino, G., Solbiati, M., Furlan, L., Mancarella, M., Colombo, G., Fanin, A., Passarella, M., Monzani, V., Canetta, C., Rovellini, A., Barbetta, L., Billi, F., Folli, C., Accordino, S., Maira, D., C. M., Hu, Motta, I., Scaramellini, N., Fracanzani, A. L., Lombardi, R., Cespiati, A., Cesari, M., Lucchi, T., Proietti, M., Calcaterra, L., Mandelli, C., Coppola, C., Cerizza, A., Pesenti, A. M., Grasselli, G., Galazzi, A., Monti, I., Galbussera, A. A., Crisafulli, E., Girelli, D., Maroccia, A., Gabbiani, D., Busti, F., Vianello, A., Biondan, M., Sartori, F., Faverio, P., Pesci, A., Zucchetti, S., Bonfanti, P., Rossi, M., Beretta, I., Spolti, A., Elia, D., Cassandro, R., Caminati, A., Cipollone, F., Guagnano, M. T., D'Ardes, D., Rossi, I., Vezzani, F., Spanevello, A., Cherubino, F., Visca, D., Contoli, M., Papi, A., Morandi, L., Battistini, N., Moreo, G. L., Iannuzzi, P., Fumagalli, D., Leone, S., Bandera, A, Nobili, A, Tettamanti, M, Harari, S, Bosari, S, Mannucci, P, Scudeller, L, Fusetti, G, Rusconi, L, Dell'Orto, S, Prati, D, Valenti, L, Giovannelli, S, Manunta, M, Lamorte, G, Ferrari, F, Gori, A, Muscatello, A, Mangioni, D, Alagna, L, Bozzi, G, Lombardi, A, Ungaro, R, Ancona, G, Zuglian, G, Bolis, M, Iannotti, N, Ludovisi, S, Comelli, A, Renisi, G, Biscarini, S, Castelli, V, Palomba, E, Fava, M, Fortina, V, Peri, C, Saltini, P, Viero, G, Itri, T, Ferroni, V, Pastore, V, Massafra, R, Liparoti, A, Muheberimana, T, Giommi, A, Bianco, R, De Azevedo, R, Chitani, G, Peyvandi, F, Gualtierotti, R, Ferrari, B, Rossio, R, Boasi, N, Pagliaro, E, Massimo, C, De Caro, M, Montano, N, Vigone, B, Bellocchi, C, Carandina, A, Fiorelli, E, Melli, V, Tobaldini, E, Blasi, F, Aliberti, S, Spotti, M, Terranova, L, Misuraca, S, D'Adda, A, Della Fiore, S, Di Pasquale, M, Contarini, M, Ori, M, Morlacchi, L, Rossetti, V, Gramegna, A, Pappalettera, M, Cavallini, M, Buscemi, A, Vicenzi, M, Rota, I, Costantino, G, Solbiati, M, Furlan, L, Mancarella, M, Colombo, G, Fanin, A, Passarella, M, Monzani, V, Canetta, C, Rovellini, A, Barbetta, L, Billi, F, Folli, C, Accordino, S, Maira, D, Hu, C, Motta, I, Scaramellini, N, Fracanzani, A, Lombardi, R, Cespiati, A, Cesari, M, Lucchi, T, Proietti, M, Calcaterra, L, Mandelli, C, Coppola, C, Cerizza, A, Pesenti, A, Grasselli, G, Galazzi, A, Monti, I, Galbussera, A, Crisafulli, E, Girelli, D, Maroccia, A, Gabbiani, D, Busti, F, Vianello, A, Biondan, M, Sartori, F, Faverio, P, Pesci, A, Zucchetti, S, Bonfanti, P, Rossi, M, Beretta, I, Spolti, A, Elia, D, Cassandro, R, Caminati, A, Cipollone, F, Guagnano, M, D'Ardes, D, Rossi, I, Vezzani, F, Spanevello, A, Cherubino, F, Visca, D, Contoli, M, Papi, A, Morandi, L, Battistini, N, Moreo, G, Iannuzzi, P, Fumagalli, D, and Leone, S
Subjects: Adult, medicine.medical_specialty, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), Critical Care, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Ce - Letter to the Editor, MEDLINE, Cohort Studies, Hospital, Internal Medicine, Medicine, Humans, Hospital Mortality, Intensive care medicine, Aged, Aged, 80 and over, business.industry, SARS-CoV-2, COVID-19, Middle Aged, Respiration, Artificial, Hospitals, Hospitalization, Survival Rate, Italy, Emergency Medicine, business, Human
Abstract: During the COVID-19 2020 outbreak, a large body of data has been provided on general management and outcomes of hospitalized COVID-19 patients. Yet, relatively little is known on characteristics and outcome of patients managed in Internal Medicine Units (IMU). To address this gap, the Italian Society of Internal Medicine has conducted a nationwide cohort multicentre study on death outcome in adult COVID-19 patients admitted and managed in IMU. This study assessed 3044 COVID-19 patients at 41 referral hospitals across Italy from February 3rd to May 8th 2020. Demographics, comorbidities, organ dysfunction, treatment, and outcomes including death were assessed. During the study period, 697 patients (22.9%) were transferred to intensive care units, and 351 died in IMU (death rate 14.9%). At admission, factors independently associated with in-hospital mortality were age (OR 2.46, p = 0.000), productive cough (OR 2.04, p = 0.000), pre-existing chronic heart failure (OR 1.58, p = 0.017) and chronic obstructive pulmonary disease (OR 1.17, p = 0.048), the number of comorbidities (OR 1.34, p = 0.000) and polypharmacy (OR 1.20, p = 0.000). Of note, up to 40% of elderly patients did not report fever at admission. Decreasing PaO
Published: 2022

42. High rates of sustained virological response despite premature discontinuation of directly acting antivirals in HCV-infected patients treated in a real-life setting

Author: Fabbiani, M, Lombardi, A, Colaneri, M, Del Poggio, P, Perini, P, D'Ambrosio, R, Degasperi, E, Dibenedetto, C, Giorgini, A, Pasulo, L, Maggiolo, F, Castelli, F, Brambilla, P, Spinelli, O, Re, T, Lleo, A, Rumi, M, Uberti-Foppa, C, Soria, A, Aghemo, A, Lampertico, P, Baiguera, C, Schiavini, M, Fagiuoli, S, Bruno, R, Borghi, M, Soffredini, R, Perbellini, R, Gori, A, Ferroni, V, Colpani, M, Manini, M, Cologni, G, Lazzaroni, S, Vinci, M, De Nicola, S, Mazzarelli, C, Angelini Zucchetti, T, Picciotto, V, Puoti, M, Rossotti, R, Landonio, S, Magni, C, Rizzardini, G, Colella, E, Columpsi, P, Gambaro, A, Spolti, A, Magnani, C, Vigano, P, Mena, M, Villa, M, Caramma, I, Basilico, C, Capelli, F, Biagiotti, S, Mazzone, A, Saladino, V, Baldacci, M, Gatti, F, Varalli, L, Morini, L, Menzaghi, B, Farinazzo, M, Meli, R, Plaz Torres, M, Fanetti, I, Orellana, D, Zermiani, P, Zuin, M, De Bona, A, D'Arminio Monforte, A, Capretti, A, Taddei, M, Soncini, M, Spinetti, A, Zaltron, S, Pigozzi, M, Rossini, A, Pan, A, Dal Zoppo, S, Zoncada, A, Memoli, M, Salpietro, S, Hamid, H, Messina, E, Colombo, A, Giglio, O, Bonfanti, P, Molteni, C, Terreni, N, Spinzi, G, Conforti, S, Clerici, E, Menozzi, F, Buscarini, E, Centenaro, R, Corbellini, A, Noventa, F, Gritti, S, Giani, P, Fabbiani M., Lombardi A., Colaneri M., Del Poggio P., Perini P., D'Ambrosio R., Degasperi E., Dibenedetto C., Giorgini A., Pasulo L., Maggiolo F., Castelli F., Brambilla P., Spinelli O., Re T., Lleo A., Rumi M., Uberti-Foppa C., Soria A., Aghemo A., Lampertico P., Baiguera C., Schiavini M., Fagiuoli S., Bruno R., Borghi M., Soffredini R., Perbellini R., Gori A., Ferroni V., Colpani M., Manini M., Cologni G., Lazzaroni S., Vinci M., De Nicola S., Mazzarelli C., Angelini Zucchetti T., Picciotto V., Puoti M., Rossotti R., Landonio S., Magni C. F., Rizzardini G., Colella E., Columpsi P., Gambaro A., Spolti A., Magnani C., Vigano P., Mena M., Villa M., Caramma I., Basilico C., Capelli F., Biagiotti S., Mazzone A., Saladino V., Baldacci M. P., Gatti F., Varalli L., Morini L., Menzaghi B., Farinazzo M., Meli R., Plaz Torres M. C., Fanetti I., Orellana D., Zermiani P., Zuin M., De Bona A., D'Arminio Monforte A., Capretti A., Taddei M. T., Soncini M., Spinetti A., Zaltron S., Pigozzi M. G., Rossini A., Pan A., Dal Zoppo S., Zoncada A., Memoli M., Salpietro S., Hamid H., Messina E., Colombo A. E., Giglio O., Bonfanti P., Molteni C., Terreni N., Spinzi G., Conforti S., Clerici E., Menozzi F., Buscarini E., Centenaro R., Corbellini A., Noventa F., Gritti S., Giani P., Fabbiani, M, Lombardi, A, Colaneri, M, Del Poggio, P, Perini, P, D'Ambrosio, R, Degasperi, E, Dibenedetto, C, Giorgini, A, Pasulo, L, Maggiolo, F, Castelli, F, Brambilla, P, Spinelli, O, Re, T, Lleo, A, Rumi, M, Uberti-Foppa, C, Soria, A, Aghemo, A, Lampertico, P, Baiguera, C, Schiavini, M, Fagiuoli, S, Bruno, R, Borghi, M, Soffredini, R, Perbellini, R, Gori, A, Ferroni, V, Colpani, M, Manini, M, Cologni, G, Lazzaroni, S, Vinci, M, De Nicola, S, Mazzarelli, C, Angelini Zucchetti, T, Picciotto, V, Puoti, M, Rossotti, R, Landonio, S, Magni, C, Rizzardini, G, Colella, E, Columpsi, P, Gambaro, A, Spolti, A, Magnani, C, Vigano, P, Mena, M, Villa, M, Caramma, I, Basilico, C, Capelli, F, Biagiotti, S, Mazzone, A, Saladino, V, Baldacci, M, Gatti, F, Varalli, L, Morini, L, Menzaghi, B, Farinazzo, M, Meli, R, Plaz Torres, M, Fanetti, I, Orellana, D, Zermiani, P, Zuin, M, De Bona, A, D'Arminio Monforte, A, Capretti, A, Taddei, M, Soncini, M, Spinetti, A, Zaltron, S, Pigozzi, M, Rossini, A, Pan, A, Dal Zoppo, S, Zoncada, A, Memoli, M, Salpietro, S, Hamid, H, Messina, E, Colombo, A, Giglio, O, Bonfanti, P, Molteni, C, Terreni, N, Spinzi, G, Conforti, S, Clerici, E, Menozzi, F, Buscarini, E, Centenaro, R, Corbellini, A, Noventa, F, Gritti, S, Giani, P, Fabbiani M., Lombardi A., Colaneri M., Del Poggio P., Perini P., D'Ambrosio R., Degasperi E., Dibenedetto C., Giorgini A., Pasulo L., Maggiolo F., Castelli F., Brambilla P., Spinelli O., Re T., Lleo A., Rumi M., Uberti-Foppa C., Soria A., Aghemo A., Lampertico P., Baiguera C., Schiavini M., Fagiuoli S., Bruno R., Borghi M., Soffredini R., Perbellini R., Gori A., Ferroni V., Colpani M., Manini M., Cologni G., Lazzaroni S., Vinci M., De Nicola S., Mazzarelli C., Angelini Zucchetti T., Picciotto V., Puoti M., Rossotti R., Landonio S., Magni C. F., Rizzardini G., Colella E., Columpsi P., Gambaro A., Spolti A., Magnani C., Vigano P., Mena M., Villa M., Caramma I., Basilico C., Capelli F., Biagiotti S., Mazzone A., Saladino V., Baldacci M. P., Gatti F., Varalli L., Morini L., Menzaghi B., Farinazzo M., Meli R., Plaz Torres M. C., Fanetti I., Orellana D., Zermiani P., Zuin M., De Bona A., D'Arminio Monforte A., Capretti A., Taddei M. T., Soncini M., Spinetti A., Zaltron S., Pigozzi M. G., Rossini A., Pan A., Dal Zoppo S., Zoncada A., Memoli M., Salpietro S., Hamid H., Messina E., Colombo A. E., Giglio O., Bonfanti P., Molteni C., Terreni N., Spinzi G., Conforti S., Clerici E., Menozzi F., Buscarini E., Centenaro R., Corbellini A., Noventa F., Gritti S., and Giani P.
Abstract: In routine clinical practice, hepatitis C virus-infected patients can prematurely discontinue the prescribed regimen for several reasons. The aim of our study was to investigate sustained virological response (SVR12) rates in patients who prematurely discontinued directly acting antiviral (DAA) regimens and to assess the shortest effective duration of DAA able to lead to SVR12. We retrospectively collected the SVR rates of patients, registered in the NAVIGATORE-Lombardia Network database from January 2015, who discontinued DAAs before the predefined end of treatment. Overall, we included 365 patients, males were the majority (213, 58.4%), mean age was 60.5 years, and 53 (14.5%) patients were HIV-co-infected. Liver cirrhosis was observed in 251 (68.8%) subjects, and the most represented genotypes were 1b (n = 168, 46%) and 3 (n = 59, 16.2%). DAA was discontinued a median of 1 (IQR 1–4) weeks before the predefined EOT, with 164 (44.9%) patients stopping DAAs at least 2 weeks before the planned schedule. In patients with F0–F3 liver fibrosis, lower rates of SVR12 were observed in patients treated for <4 weeks: 50% (n = 2/4) vs. 99.1% (n = 109/110) for ≥4 weeks, p = 0.003. In patients with liver cirrhosis, lower rates of SVR12 were observed in patients treated <8 weeks: 83.3% (n = 25/30) vs. 94.6% (n = 209/221) for ≥8 weeks, p = 0.038. Despite premature discontinuation of DAA, high SVR12 rates were observed in a real-life setting for treatment lasting at least 4 weeks in patients with liver fibrosis F0–F3 and 8 weeks in those with liver cirrhosis. On this basis, feasibility of reducing DAA treatment duration should be explored in randomized clinical trials.
Published: 2021

43. Burden of Disease in PWH Harboring a Multidrug-Resistant Virus: Data from the PRESTIGIO Registry

Author: Galli, L, Parisi, M, Poli, A, Menozzi, M, Fiscon, M, Garlassi, E, Francisci, D, DI Biagio, A, Sterrantino, G, Fornabaio, C, Degli Antoni, A, Angarano, G, Fusco, F, D'Arminio Monforte, A, Corbelli, G, Santoro, M, Zazzi, M, Castagna, A, Gianotti, N, Maggiolo, F, Calza, L, Foca, E, Cenderello, G, Rusconi, S, Mussini, C, Antinori, A, Gagliardini, R, Bonora, S, Ferrara, M, Galli, A, Carini, E, Bigoloni, A, Tavio, M, Butini, L, Giacometti, A, Vaccher, E, Martellotta, F, Da Ros, V, Saracino, A, Balena, F, Comi, L, DI Filippo, E, Valenti, D, Suardi, C, Mazzola, B, Viale, P, Del Turco, E, Ramirez, M, Castelli, F, Celotti, A, Brognoli, F, Bonoldi, G, Menzaghi, B, Abeli, C, Farinazzo, M, Ortu, F, Campus, M, Cacopardo, B, Celesia, M, Pan, A, Bartoloni, A, Rinaldi, F, Giache, S, Pierluigi, B, Vichi, F, Santantonio, T, Ferrara, S, Bruno, S, Cassola, G, Marcello, F, Calautti, F, Bassetti, M, Bruzzone, B, Artioli, S, Lazzarin, A, Canetti, D, Galli, M, Formenti, T, Morena, V, Gabrieli, A, Gazzola, L, Merlini, E, Minieri, V, Gori, A, Bandera, A, Pastore, V, Ferroni, V, Puoti, M, Moioli, C, Vassalli, S, Enrica, R, Giulia, N, Beghetto, B, Manzillo, E, Franco, A, Cattelan, A, Marinello, S, Cavinato, S, Macario, A, Cascio, A, Mazzola, G, Antoni, A, Ferrari, C, Laccabue, D, Filice, G, Gulminetti, R, Pagnucco, L, Asti, A, Schiaroli, E, Papalini, C, Italiani, F, DI Pietro, M, Magnani, G, Elisa, G, Barchi, E, Corsini, R, Vergori, A, Cicalini, S, Onnelli, G, Giannetti, A, Cauda, R, Ciccullo, A, La Monica, S, Vullo, V, Dettorre, G, Cavallari, E, Andreoni, M, Malagnino, V, Ceccarelli, L, Viviani, F, Sasset, L, Dentone, C, Rossetti, B, Modica, S, Borgo, V, DI Perri, G, Carcieri, C, Malena, M, Padovani, B, Luzzati, R, Centonze, S, Valentinotti, R, Galli L., Parisi M. R., Poli A., Menozzi M., Fiscon M., Garlassi E., Francisci D., DI Biagio A., Sterrantino G., Fornabaio C., Degli Antoni A., Angarano G., Fusco F. M., D'Arminio Monforte A., Corbelli G. M., Santoro M. M., Zazzi M., Castagna A., Gianotti N., Maggiolo F., Calza L., Foca E., Cenderello G., Rusconi S., Mussini C., Antinori A., Gagliardini R., Bonora S., Ferrara M., Santoro M., Galli A., Carini E., Bigoloni A., Tavio M., Butini L., Giacometti A., Vaccher E., Martellotta F., Da Ros V., Saracino A., Balena F., Comi L., DI Filippo E., Valenti D., Suardi C., Mazzola B., Viale P., Del Turco E. R., Ramirez M. V., Castelli F., Celotti A., Brognoli F., Bonoldi G., Menzaghi B., Abeli C., Farinazzo M., Ortu F., Campus M., Cacopardo B., Celesia M., Pan A., Bartoloni A., Rinaldi F., Giache S., Pierluigi B., Vichi F., Santantonio T., Ferrara S., Bruno S. R., Cassola G., Marcello F., Calautti F., Bassetti M., Bruzzone B., Artioli S., Lazzarin A., Canetti D., Galli M., Formenti T., Morena V., Gabrieli A., Gazzola L., Merlini E., Minieri V., Gori A., Bandera A., Pastore V., Ferroni V., Puoti M., Moioli C., Vassalli S., Enrica R., Giulia N., Beghetto B., Manzillo E., Franco A., Cattelan A. M., Marinello S., Cavinato S., MacArio A., Cascio A., Mazzola G., Antoni A. M. D., Ferrari C., Laccabue D., Filice G., Gulminetti R., Pagnucco L., Asti A., Schiaroli E., Papalini C., Italiani F., DI Pietro M., Magnani G., Elisa G., Barchi E., Corsini R., Vergori A., Cicalini S., Onnelli G., Giannetti A., Cauda R., Ciccullo A., La Monica S., Vullo V., Dettorre G., Cavallari E. N., Andreoni M., Malagnino V., Ceccarelli L., Viviani F., Sasset L., Dentone C., Rossetti B., Modica S., Borgo V., DI Perri G., Carcieri C., Malena M., Padovani B., Luzzati R., Centonze S., Valentinotti R., Galli, L, Parisi, M, Poli, A, Menozzi, M, Fiscon, M, Garlassi, E, Francisci, D, DI Biagio, A, Sterrantino, G, Fornabaio, C, Degli Antoni, A, Angarano, G, Fusco, F, D'Arminio Monforte, A, Corbelli, G, Santoro, M, Zazzi, M, Castagna, A, Gianotti, N, Maggiolo, F, Calza, L, Foca, E, Cenderello, G, Rusconi, S, Mussini, C, Antinori, A, Gagliardini, R, Bonora, S, Ferrara, M, Galli, A, Carini, E, Bigoloni, A, Tavio, M, Butini, L, Giacometti, A, Vaccher, E, Martellotta, F, Da Ros, V, Saracino, A, Balena, F, Comi, L, DI Filippo, E, Valenti, D, Suardi, C, Mazzola, B, Viale, P, Del Turco, E, Ramirez, M, Castelli, F, Celotti, A, Brognoli, F, Bonoldi, G, Menzaghi, B, Abeli, C, Farinazzo, M, Ortu, F, Campus, M, Cacopardo, B, Celesia, M, Pan, A, Bartoloni, A, Rinaldi, F, Giache, S, Pierluigi, B, Vichi, F, Santantonio, T, Ferrara, S, Bruno, S, Cassola, G, Marcello, F, Calautti, F, Bassetti, M, Bruzzone, B, Artioli, S, Lazzarin, A, Canetti, D, Galli, M, Formenti, T, Morena, V, Gabrieli, A, Gazzola, L, Merlini, E, Minieri, V, Gori, A, Bandera, A, Pastore, V, Ferroni, V, Puoti, M, Moioli, C, Vassalli, S, Enrica, R, Giulia, N, Beghetto, B, Manzillo, E, Franco, A, Cattelan, A, Marinello, S, Cavinato, S, Macario, A, Cascio, A, Mazzola, G, Antoni, A, Ferrari, C, Laccabue, D, Filice, G, Gulminetti, R, Pagnucco, L, Asti, A, Schiaroli, E, Papalini, C, Italiani, F, DI Pietro, M, Magnani, G, Elisa, G, Barchi, E, Corsini, R, Vergori, A, Cicalini, S, Onnelli, G, Giannetti, A, Cauda, R, Ciccullo, A, La Monica, S, Vullo, V, Dettorre, G, Cavallari, E, Andreoni, M, Malagnino, V, Ceccarelli, L, Viviani, F, Sasset, L, Dentone, C, Rossetti, B, Modica, S, Borgo, V, DI Perri, G, Carcieri, C, Malena, M, Padovani, B, Luzzati, R, Centonze, S, Valentinotti, R, Galli L., Parisi M. R., Poli A., Menozzi M., Fiscon M., Garlassi E., Francisci D., DI Biagio A., Sterrantino G., Fornabaio C., Degli Antoni A., Angarano G., Fusco F. M., D'Arminio Monforte A., Corbelli G. M., Santoro M. M., Zazzi M., Castagna A., Gianotti N., Maggiolo F., Calza L., Foca E., Cenderello G., Rusconi S., Mussini C., Antinori A., Gagliardini R., Bonora S., Ferrara M., Santoro M., Galli A., Carini E., Bigoloni A., Tavio M., Butini L., Giacometti A., Vaccher E., Martellotta F., Da Ros V., Saracino A., Balena F., Comi L., DI Filippo E., Valenti D., Suardi C., Mazzola B., Viale P., Del Turco E. R., Ramirez M. V., Castelli F., Celotti A., Brognoli F., Bonoldi G., Menzaghi B., Abeli C., Farinazzo M., Ortu F., Campus M., Cacopardo B., Celesia M., Pan A., Bartoloni A., Rinaldi F., Giache S., Pierluigi B., Vichi F., Santantonio T., Ferrara S., Bruno S. R., Cassola G., Marcello F., Calautti F., Bassetti M., Bruzzone B., Artioli S., Lazzarin A., Canetti D., Galli M., Formenti T., Morena V., Gabrieli A., Gazzola L., Merlini E., Minieri V., Gori A., Bandera A., Pastore V., Ferroni V., Puoti M., Moioli C., Vassalli S., Enrica R., Giulia N., Beghetto B., Manzillo E., Franco A., Cattelan A. M., Marinello S., Cavinato S., MacArio A., Cascio A., Mazzola G., Antoni A. M. D., Ferrari C., Laccabue D., Filice G., Gulminetti R., Pagnucco L., Asti A., Schiaroli E., Papalini C., Italiani F., DI Pietro M., Magnani G., Elisa G., Barchi E., Corsini R., Vergori A., Cicalini S., Onnelli G., Giannetti A., Cauda R., Ciccullo A., La Monica S., Vullo V., Dettorre G., Cavallari E. N., Andreoni M., Malagnino V., Ceccarelli L., Viviani F., Sasset L., Dentone C., Rossetti B., Modica S., Borgo V., DI Perri G., Carcieri C., Malena M., Padovani B., Luzzati R., Centonze S., and Valentinotti R.
Abstract: Background: Currently, no data are available on the burden of morbidity and mortality in people with HIV-1 (PWH) harboring a 4-class drug-resistant (4DR) virus (nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, protease inhibitors, integrase strand transfer inhibitors). The study aimed to assess the incidence of clinical events and death in this population. Methods: This was a cohort study on PWH from the PRESTIGIO Registry with a documented 4DR virus. Burden of disease was defined as the occurrence of any new event including an AIDS-defining event (ADE) or non-AIDS-defining event (NADE) or death from any cause after 4DR evidence (baseline). Cox regression models evaluated factors associated with the risk of new clinical events/death. Results: Among 148 PWH followed for a median (interquartile range) of 47 (32-84) months after 4DR evidence, 38 PWH had 62 new events or died from any cause (incidence rate, 9.12/100 person-years of follow-up; 95% CI = 6.85-11.39): 12 deaths (6 AIDS-related and 6 non-AIDS-related), 18 ADEs, 32 NADEs; 20 of the 38 NADEs (45%) of the incident clinical events were malignancies. The 4-year cumulative incidence of death was 6% (95% CI, 3%-13%), and that of ≥1 event or death was 22% (95% CI, 16%-31%). A higher risk of new clinical events/death was more likely in PWH with previous clinical events (adjusted hazard ratio [aHR], 2.67; 95% CI, 1.07-6.67) and marginally associated with lower baseline CD4+/CD8+ ratio (aHR, 0.82; 95% CI, 0.65-1.02). Conclusions: PWH harboring 4DR have a high burden of disease with a worrying incidence of malignancies, strongly advising for close prevention and monitoring interventions as well as access to innovative therapeutic strategies, especially in people with a history of clinical events and low CD4+/CD8+ ratio.
Published: 2020

44. Burden of Disease in PWH Harboring a Multidrug-Resistant Virus: Data from the PRESTIGIO Registry

Author: Galli, L., Parisi, M. R., Poli, A., Menozzi, M., Fiscon, M., Garlassi, E., Francisci, D., DI Biagio, A., Sterrantino, G., Fornabaio, C., Degli Antoni, A., Angarano, G., Fusco, F. M., D'Arminio Monforte, A., Corbelli, G. M., Santoro, M. M., Zazzi, M., Castagna, A., Gianotti, N., Maggiolo, F., Calza, L., Foca, E., Cenderello, G., Rusconi, S., Mussini, C., Antinori, A., Gagliardini, R., Bonora, S., Ferrara, M., Santoro, M., Galli, A., Carini, E., Bigoloni, A., Tavio, M., Butini, L., Giacometti, A., Vaccher, E., Martellotta, F., Da Ros, V., Saracino, A., Balena, F., Comi, L., DI Filippo, E., Valenti, D., Suardi, C., Mazzola, B., Viale, P., Del Turco, E. R., Ramirez, M. V., Castelli, F., Celotti, A., Brognoli, F., Bonoldi, G., Menzaghi, B., Abeli, C., Farinazzo, M., Ortu, F., Campus, M., Cacopardo, B., Celesia, M., Pan, A., Bartoloni, A., Rinaldi, F., Giache, S., Pierluigi, B., Vichi, F., Santantonio, T., Ferrara, S., Bruno, S. R., Cassola, G., Marcello, F., Calautti, F., Bassetti, M., Bruzzone, B., Artioli, S., Lazzarin, A., Canetti, D., Galli, M., Formenti, T., Morena, V., Gabrieli, A., Gazzola, L., Merlini, E., Minieri, V., Gori, A., Bandera, A., Pastore, V., Ferroni, V., Puoti, M., Moioli, C., Vassalli, S., Enrica, R., Giulia, N., Beghetto, B., Manzillo, E., Franco, A., Cattelan, A. M., Marinello, S., Cavinato, S., Macario, A., Cascio, A., Mazzola, G., Antoni, A. M. D., Ferrari, C., Laccabue, D., Filice, G., Gulminetti, R., Pagnucco, L., Asti, A., Schiaroli, E., Papalini, C., Italiani, F., DI Pietro, M., Magnani, G., Elisa, G., Barchi, E., Corsini, R., Vergori, A., Cicalini, S., Onnelli, G., Giannetti, A., Cauda, R., Ciccullo, A., La Monica, S., Vullo, V., Dettorre, G., Cavallari, E. N., Andreoni, M., Malagnino, V., Ceccarelli, L., Viviani, F., Sasset, L., Dentone, C., Rossetti, B., Modica, S., Borgo, V., DI Perri, G., Carcieri, C., Malena, M., Padovani, B., Luzzati, R., Centonze, S., Valentinotti, R., Galli L., Parisi M.R., Poli A., Menozzi M., Fiscon M., Garlassi E., Francisci D., DI Biagio A., Sterrantino G., Fornabaio C., Degli Antoni A., Angarano G., Fusco F.M., D'Arminio Monforte A., Corbelli G.M., Santoro M.M., Zazzi M., Castagna A., Gianotti N., Maggiolo F., Calza L., Foca E., Cenderello G., Rusconi S., Mussini C., Antinori A., Gagliardini R., Bonora S., Ferrara M., Santoro M., Galli A., Carini E., Bigoloni A., Tavio M., Butini L., Giacometti A., Vaccher E., Martellotta F., Da Ros V., Saracino A., Balena F., Comi L., DI Filippo E., Valenti D., Suardi C., Mazzola B., Viale P., Del Turco E.R., Ramirez M.V., Castelli F., Celotti A., Brognoli F., Bonoldi G., Menzaghi B., Abeli C., Farinazzo M., Ortu F., Campus M., Cacopardo B., Celesia M., Pan A., Bartoloni A., Rinaldi F., Giache S., Pierluigi B., Vichi F., Santantonio T., Ferrara S., Bruno S.R., Cassola G., Marcello F., Calautti F., Bassetti M., Bruzzone B., Artioli S., Lazzarin A., Canetti D., Galli M., Formenti T., Morena V., Gabrieli A., Gazzola L., Merlini E., Minieri V., Gori A., Bandera A., Pastore V., Ferroni V., Puoti M., Moioli C., Vassalli S., Enrica R., Giulia N., Beghetto B., Manzillo E., Franco A., Cattelan A.M., Marinello S., Cavinato S., MacArio A., Cascio A., Mazzola G., Antoni A.M.D., Ferrari C., Laccabue D., Filice G., Gulminetti R., Pagnucco L., Asti A., Frsdi E., Schiaroli E., Papalini C., Italiani F., DI Pietro M., Magnani G., Elisa G., Barchi E., Corsini R., Vergori A., Cicalini S., Onnelli G., Giannetti A., Cauda R., Ciccullo A., La Monica S., Vullo V., Dettorre G., Cavallari E.N., Andreoni M., Malagnino V., Ceccarelli L., Viviani F., Sasset L., Dentone C., Rossetti B., Modica S., Borgo V., DI Perri G., Carcieri C., Malena M., Padovani B., Luzzati R., Centonze S., Valentinotti R., Galli, L, Parisi, M, Poli, A, Menozzi, M, Fiscon, M, Garlassi, E, Francisci, D, DI Biagio, A, Sterrantino, G, Fornabaio, C, Degli Antoni, A, Angarano, G, Fusco, F, D'Arminio Monforte, A, Corbelli, G, Santoro, M, Zazzi, M, Castagna, A, Gianotti, N, Maggiolo, F, Calza, L, Foca, E, Cenderello, G, Rusconi, S, Mussini, C, Antinori, A, Gagliardini, R, Bonora, S, Ferrara, M, Galli, A, Carini, E, Bigoloni, A, Tavio, M, Butini, L, Giacometti, A, Vaccher, E, Martellotta, F, Da Ros, V, Saracino, A, Balena, F, Comi, L, DI Filippo, E, Valenti, D, Suardi, C, Mazzola, B, Viale, P, Del Turco, E, Ramirez, M, Castelli, F, Celotti, A, Brognoli, F, Bonoldi, G, Menzaghi, B, Abeli, C, Farinazzo, M, Ortu, F, Campus, M, Cacopardo, B, Celesia, M, Pan, A, Bartoloni, A, Rinaldi, F, Giache, S, Pierluigi, B, Vichi, F, Santantonio, T, Ferrara, S, Bruno, S, Cassola, G, Marcello, F, Calautti, F, Bassetti, M, Bruzzone, B, Artioli, S, Lazzarin, A, Canetti, D, Galli, M, Formenti, T, Morena, V, Gabrieli, A, Gazzola, L, Merlini, E, Minieri, V, Gori, A, Bandera, A, Pastore, V, Ferroni, V, Puoti, M, Moioli, C, Vassalli, S, Enrica, R, Giulia, N, Beghetto, B, Manzillo, E, Franco, A, Cattelan, A, Marinello, S, Cavinato, S, Macario, A, Cascio, A, Mazzola, G, Antoni, A, Ferrari, C, Laccabue, D, Filice, G, Gulminetti, R, Pagnucco, L, Asti, A, Schiaroli, E, Papalini, C, Italiani, F, DI Pietro, M, Magnani, G, Elisa, G, Barchi, E, Corsini, R, Vergori, A, Cicalini, S, Onnelli, G, Giannetti, A, Cauda, R, Ciccullo, A, La Monica, S, Vullo, V, Dettorre, G, Cavallari, E, Andreoni, M, Malagnino, V, Ceccarelli, L, Viviani, F, Sasset, L, Dentone, C, Rossetti, B, Modica, S, Borgo, V, DI Perri, G, Carcieri, C, Malena, M, Padovani, B, Luzzati, R, Centonze, S, Valentinotti, R, Galli, Laura, Parisi, Maria Rita, Poli, Andrea, Menozzi, Marianna, Fiscon, Marta, Garlassi, Elisa, Francisci, Daniela, Di Biagio, Antonio, Sterrantino, Gaetana, Fornabaio, Chiara, Degli Antoni, Anna, Angarano, Gioacchino, Fusco, Francesco Maria, D'Arminio Monforte, Antonella, Corbelli, Giulio Maria, Santoro, Maria Mercede, Zazzi, Maurizio, and Castagna, Antonella
Subjects: 0301 basic medicine, medicine.medical_specialty, 4-class drug resistance, AIDS-defining event, cancer, death, non-AIDS-defining event, Population, Major Articles, Settore MED/07, 03 medical and health sciences, 0302 clinical medicine, Interquartile range, Internal medicine, medicine, Cumulative incidence, 030212 general & internal medicine, education, Disease burden, education.field_of_study, Proportional hazards model, business.industry, Incidence (epidemiology), Hazard ratio, 030112 virology, AcademicSubjects/MED00290, Infectious Diseases, Oncology, business, Cohort study
Abstract: BackgroundCurrently, no data are available on the burden of morbidity and mortality in people with HIV-1 (PWH) harboring a 4-class drug-resistant (4DR) virus (nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, protease inhibitors, integrase strand transfer inhibitors). The study aimed to assess the incidence of clinical events and death in this population.MethodsThis was a cohort study on PWH from the PRESTIGIO Registry with a documented 4DR virus. Burden of disease was defined as the occurrence of any new event including an AIDS-defining event (ADE) or non-AIDS-defining event (NADE) or death from any cause after 4DR evidence (baseline). Cox regression models evaluated factors associated with the risk of new clinical events/death.ResultsAmong 148 PWH followed for a median (interquartile range) of 47 (32–84) months after 4DR evidence, 38 PWH had 62 new events or died from any cause (incidence rate, 9.12/100 person-years of follow-up; 95% CI = 6.85–11.39): 12 deaths (6 AIDS-related and 6 non-AIDS-related), 18 ADEs, 32 NADEs; 20 of the 38 NADEs (45%) of the incident clinical events were malignancies. The 4-year cumulative incidence of death was 6% (95% CI, 3%–13%), and that of ≥1 event or death was 22% (95% CI, 16%–31%). A higher risk of new clinical events/death was more likely in PWH with previous clinical events (adjusted hazard ratio [aHR], 2.67; 95% CI, 1.07–6.67) and marginally associated with lower baseline CD4+/CD8+ ratio (aHR, 0.82; 95% CI, 0.65–1.02).ConclusionsPWH harboring 4DR have a high burden of disease with a worrying incidence of malignancies, strongly advising for close prevention and monitoring interventions as well as access to innovative therapeutic strategies, especially in people with a history of clinical events and low CD4+/CD8+ ratio.
Published: 2020

45. Clinical risk scores for the early prediction of severe outocomes in patients hospitalized for COVID-19: comment

Author: Rossio R., Tettamanti M., Nobili A., Harari S., Mannucci P. M., Bandera A., Peyvandi F., Bosari S., Scudeller L., Fusetti G., Rusconi L., Dell'Orto S., Prati D., Valenti L., Giovannelli S., Manunta M., Lamorte G., Ferrari F., Gori A., Muscatello A., Mangioni D., Alagna L., Bozzi G., Lombardi A., Ungaro R., Ancona G., Zuglian G., Bolis M., Iannotti N., Ludovisi S., Comelli A., Renisi G., Biscarini S., Castelli V., Palomba E., Fava M., Fortina V., Peri C. A., Saltini P., Viero G., Itri T., Ferroni V., Pastore V., Massafra R., Liparoti A., Muheberimana T., Giommi A., Bianco R., De Azevedo R. M., Chitani G. E., Gualtierotti R., Ferrari B., Boasi N., Pagliaro E., Massimo C., De Caro M., Giachi A., Montano N., Vigone B., Bellocchi C., Carandina A., Fiorelli E., Melli V., Tobaldini E., Blasi F., Aliberti S., Spotti M., Terranova L., Misuraca S., D'Adda A., Fiore S. D., Di Pasquale M., Mantero M., Contarini M., Ori M., Morlacchi L., Rossetti V., Gramegna A., Pappalettera M., Cavallini M., Buscemi A., Vicenzi M., Rota I., Costantino G., Solbiati M., Furlan L., Mancarella M., Colombo G., Fanin A., Passarella M., Monzani V., Canetta C., Rovellini A., Barbetta L., Billi F., Folli C., Accordino S., Maira D., Hu C. M., Motta I., Scaramellini N., Fracanzani A. L., Lombardi R., Cespiati A., Cesari M., Lucchi T., Proietti M., Calcaterra L., Mandelli C., Coppola C., Cerizza A., Pesenti A. M., Grasselli G., Galazzi A., Monti I., Galbussera A. A., Crisafulli E., Girelli D., Maroccia A., Gabbiani D., Busti F., Vianello A., Biondan M., Sartori F., Faverio P., Pesci A., Zucchetti S., Bonfanti P., Rossi M., Beretta I., Spolti A., Elia D., Cassandro R., Caminati A., Cipollone F., Guagnano M. T., D'Ardes D., Rossi I., Vezzani F., Spanevello A., Cherubino F., Visca D., Contoli M., Papi A., Morandi L., Battistini N., Moreo G. L., Iannuzzi P., Fumagalli D., Leone S., Rossio, R, Tettamanti, M, Nobili, A, Harari, S, Mannucci, P, Bandera, A, Peyvandi, F, Bosari, S, Scudeller, L, Fusetti, G, Rusconi, L, Dell'Orto, S, Prati, D, Valenti, L, Giovannelli, S, Manunta, M, Lamorte, G, Ferrari, F, Gori, A, Muscatello, A, Mangioni, D, Alagna, L, Bozzi, G, Lombardi, A, Ungaro, R, Ancona, G, Zuglian, G, Bolis, M, Iannotti, N, Ludovisi, S, Comelli, A, Renisi, G, Biscarini, S, Castelli, V, Palomba, E, Fava, M, Fortina, V, Peri, C, Saltini, P, Viero, G, Itri, T, Ferroni, V, Pastore, V, Massafra, R, Liparoti, A, Muheberimana, T, Giommi, A, Bianco, R, De Azevedo, R, Chitani, G, Gualtierotti, R, Ferrari, B, Boasi, N, Pagliaro, E, Massimo, C, De Caro, M, Giachi, A, Montano, N, Vigone, B, Bellocchi, C, Carandina, A, Fiorelli, E, Melli, V, Tobaldini, E, Blasi, F, Aliberti, S, Spotti, M, Terranova, L, Misuraca, S, D'Adda, A, Fiore, S, Di Pasquale, M, Mantero, M, Contarini, M, Ori, M, Morlacchi, L, Rossetti, V, Gramegna, A, Pappalettera, M, Cavallini, M, Buscemi, A, Vicenzi, M, Rota, I, Costantino, G, Solbiati, M, Furlan, L, Mancarella, M, Colombo, G, Fanin, A, Passarella, M, Monzani, V, Canetta, C, Rovellini, A, Barbetta, L, Billi, F, Folli, C, Accordino, S, Maira, D, Hu, C, Motta, I, Scaramellini, N, Fracanzani, A, Lombardi, R, Cespiati, A, Cesari, M, Lucchi, T, Proietti, M, Calcaterra, L, Mandelli, C, Coppola, C, Cerizza, A, Pesenti, A, Grasselli, G, Galazzi, A, Monti, I, Galbussera, A, Crisafulli, E, Girelli, D, Maroccia, A, Gabbiani, D, Busti, F, Vianello, A, Biondan, M, Sartori, F, Faverio, P, Pesci, A, Zucchetti, S, Bonfanti, P, Rossi, M, Beretta, I, Spolti, A, Elia, D, Cassandro, R, Caminati, A, Cipollone, F, Guagnano, M, D'Ardes, D, Rossi, I, Vezzani, F, Spanevello, A, Cherubino, F, Visca, D, Contoli, M, Papi, A, Morandi, L, Battistini, N, Moreo, G, Iannuzzi, P, Fumagalli, D, and Leone, S
Subjects: Male, Outcome Assessment, Disease, 030204 cardiovascular system & hematology, Respiratory failure, 0302 clinical medicine, Risk Factors, Epidemiology, Early prediction, Outcome Assessment, Health Care, 030212 general & internal medicine, Framingham Risk Score, Respiration, Area under the curve, Middle Aged, Hospitalization, Survival Rate, Italy, Artificial, Emergency Medicine, Female, Clinical risk factor, 2019-20 coronavirus outbreak, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Ce - Letter to the Editor, MEDLINE, Risk Assessment, 03 medical and health sciences, Predictive Value of Tests, Internal medicine, Internal Medicine, medicine, Intubation, Intratracheal, Humans, In patient, Derivation, COVID-19, Risk prediction model, SARS-CoV 2, Selection (genetic algorithm), Aged, Retrospective Studies, SARS-CoV-2, business.industry, Retrospective cohort study, Respiration, Artificial, Im - Original, Health Care, Intratracheal, ROC Curve, Intubation, business
Abstract: Coronavirus disease of 2019 (COVID-19) is associated with severe acute respiratory failure. Early identification of high-risk COVID-19 patients is crucial. We aimed to derive and validate a simple score for the prediction of severe outcomes. A retrospective cohort study of patients hospitalized for COVID-19 was carried out by the Italian Society of Internal Medicine. Epidemiological, clinical, laboratory, and treatment variables were collected at hospital admission at five hospitals. Three algorithm selection models were used to construct a predictive risk score: backward Selection, Least Absolute Shrinkage and Selection Operator (LASSO), and Random Forest. Severe outcome was defined as the composite of need for non-invasive ventilation, need for orotracheal intubation, or death. A total of 610 patients were included in the analysis, 313 had a severe outcome. The subset for the derivation analysis included 335 patients, the subset for the validation analysis 275 patients. The LASSO selection identified 6 variables (age, history of coronary heart disease, CRP, AST, D-dimer, and neutrophil/lymphocyte ratio) and resulted in the best performing score with an area under the curve of 0.79 in the derivation cohort and 0.80 in the validation cohort. Using a cut-off of 7 out of 13 points, sensitivity was 0.93, specificity 0.34, positive predictive value 0.59, and negative predictive value 0.82. The proposed score can identify patients at low risk for severe outcome who can be safely managed in a low-intensity setting after hospital admission for COVID-19.
Published: 2021

46. High rates of sustained virological response despite premature discontinuation of directly acting antivirals in HCV-infected patients treated in a real-life setting

Author: Fabbiani M., Lombardi A., Colaneri M., Del Poggio P., Perini P., D'Ambrosio R., Degasperi E., Dibenedetto C., Giorgini A., Pasulo L., Maggiolo F., Castelli F., Brambilla P., Spinelli O., Re T., Lleo A., Rumi M., Uberti-Foppa C., Soria A., Aghemo A., Lampertico P., Baiguera C., Schiavini M., Fagiuoli S., Bruno R., Borghi M., Soffredini R., Perbellini R., Gori A., Ferroni V., Colpani M., Manini M., Cologni G., Lazzaroni S., Vinci M., De Nicola S., Mazzarelli C., Angelini Zucchetti T., Picciotto V., Puoti M., Rossotti R., Landonio S., Magni C. F., Rizzardini G., Colella E., Columpsi P., Gambaro A., Spolti A., Magnani C., Vigano P., Mena M., Villa M., Caramma I., Basilico C., Capelli F., Biagiotti S., Mazzone A., Saladino V., Baldacci M. P., Gatti F., Varalli L., Morini L., Menzaghi B., Farinazzo M., Meli R., Plaz Torres M. C., Fanetti I., Orellana D., Zermiani P., Zuin M., De Bona A., D'Arminio Monforte A., Capretti A., Taddei M. T., Soncini M., Spinetti A., Zaltron S., Pigozzi M. G., Rossini A., Pan A., Dal Zoppo S., Zoncada A., Memoli M., Salpietro S., Hamid H., Messina E., Colombo A. E., Giglio O., Bonfanti P., Molteni C., Terreni N., Spinzi G., Conforti S., Clerici E., Menozzi F., Buscarini E., Centenaro R., Corbellini A., Noventa F., Gritti S., Giani P., Fabbiani, Massimiliano, Lombardi, Andrea, Colaneri, Marta, Del Poggio, Paolo, Perini, Paolo, D'Ambrosio, Roberta, Degasperi, Elisabetta, Dibenedetto, Clara, Giorgini, Alessia, Pasulo, Luisa, Maggiolo, Franco, Castelli, Francesco, Brambilla, Paola, Spinelli, Ombretta, Tiziana, Re, Lleo, Ana, Rumi, Mariagrazia, Uberti-Foppa, Caterina, Soria, Alessandro, Aghemo, Alessio, Lampertico, Pietro, Baiguera, Chiara, Schiavini, Monica, Fagiuoli, Stefano, Bruno, Raffaele, Fabbiani, M, Lombardi, A, Colaneri, M, Del Poggio, P, Perini, P, D'Ambrosio, R, Degasperi, E, Dibenedetto, C, Giorgini, A, Pasulo, L, Maggiolo, F, Castelli, F, Brambilla, P, Spinelli, O, Re, T, Lleo, A, Rumi, M, Uberti-Foppa, C, Soria, A, Aghemo, A, Lampertico, P, Baiguera, C, Schiavini, M, Fagiuoli, S, Bruno, R, Borghi, M, Soffredini, R, Perbellini, R, Gori, A, Ferroni, V, Colpani, M, Manini, M, Cologni, G, Lazzaroni, S, Vinci, M, De Nicola, S, Mazzarelli, C, Angelini Zucchetti, T, Picciotto, V, Puoti, M, Rossotti, R, Landonio, S, Magni, C, Rizzardini, G, Colella, E, Columpsi, P, Gambaro, A, Spolti, A, Magnani, C, Vigano, P, Mena, M, Villa, M, Caramma, I, Basilico, C, Capelli, F, Biagiotti, S, Mazzone, A, Saladino, V, Baldacci, M, Gatti, F, Varalli, L, Morini, L, Menzaghi, B, Farinazzo, M, Meli, R, Plaz Torres, M, Fanetti, I, Orellana, D, Zermiani, P, Zuin, M, De Bona, A, D'Arminio Monforte, A, Capretti, A, Taddei, M, Soncini, M, Spinetti, A, Zaltron, S, Pigozzi, M, Rossini, A, Pan, A, Dal Zoppo, S, Zoncada, A, Memoli, M, Salpietro, S, Hamid, H, Messina, E, Colombo, A, Giglio, O, Bonfanti, P, Molteni, C, Terreni, N, Spinzi, G, Conforti, S, Clerici, E, Menozzi, F, Buscarini, E, Centenaro, R, Corbellini, A, Noventa, F, Gritti, S, and Giani, P
Subjects: Simeprevir, Male, medicine.medical_specialty, Cirrhosis, SVR, Sofosbuvir, Sustained Virologic Response, liver cirrhosis, antiviral treatment, Hepacivirus, Antiviral Agents, law.invention, Randomized controlled trial, law, Virology, Internal medicine, Medicine, Humans, chronic hepatitis C, Prospective cohort study, DAA, Retrospective Studies, Hepatology, liver cirrhosi, business.industry, Hepatitis C, Hepatitis C, Chronic, Middle Aged, medicine.disease, Discontinuation, Regimen, Infectious Diseases, Treatment Outcome, business, medicine.drug
Abstract: In routine clinical practice, hepatitis C virus-infected patients can prematurely discontinue the prescribed regimen for several reasons. The aim of our study was to investigate sustained virological response (SVR12) rates in patients who prematurely discontinued directly acting antiviral (DAA) regimens and to assess the shortest effective duration of DAA able to lead to SVR12. We retrospectively collected the SVR rates of patients, registered in the NAVIGATORE-Lombardia Network database from January 2015, who discontinued DAAs before the predefined end of treatment. Overall, we included 365 patients, males were the majority (213, 58.4%), mean age was 60.5years, and 53 (14.5%) patients were HIV-co-infected. Liver cirrhosis was observed in 251 (68.8%) subjects, and the most represented genotypes were 1b (n=168, 46%) and 3 (n=59, 16.2%). DAA was discontinued a median of 1 (IQR 1–4) weeks before the predefined EOT, with 164 (44.9%) patients stopping DAAs at least 2weeks before the planned schedule. In patients with F0–F3 liver fibrosis, lower rates of SVR12 were observed in patients treated for
Published: 2021

47. Injection of a Body into a Geodesic: Lessons Learnt from the LISA Pathfinder Case

Author: Bortoluzzi, Daniele, Armano, M, Audley, H, Auger, G, Baird, J, Binetruy, P, Born, M, Bortoluzzi, D, Brandt, N, Bursi, A, Caleno, M, Cavalleri, A, Cesarini, A, Conklin, J, Cruise, M, Danzmann, K, Diepholz, I, Dolesi, R, Dunbar, N, Ferraioli, L, Ferroni, V, Fitzsimons, E, Freschi, M, Slutsky, J, and Thorpe, J
Subjects: Mechanical Engineering
Abstract: Launch lock and release mechanisms constitute a common space business, however, some science missions due to very challenging functional and performance requirements need the development and testing of dedicated systems. In the LISA Pathfinder mission, a gold-coated 2-kg test mass must be injected into a nearly pure geodesic trajectory with a minimal residual velocity with respect to the spacecraft. This task is performed by the Grabbing Positioning and Release Mechanism, which has been tested on-ground to provide the required qualification. In this paper, we describe the test method that analyzes the main contributions to the mechanism performance and focuses on the critical parameters affecting the residual test mass velocity at the injection into the geodesic trajectory. The test results are also presented and discussed.
Published: 2016

48. Sensor Noise in LISA Pathfinder: In-Flight Performance of the Optical Test Mass Readout

Author: Armano, M., Audley, H., Baird, J., Binetruy, P., Born, M., Bortoluzzi, D., Brandt, N., Castelli, E., Cavalleri, A., Cesarini, A., Cruise, A. M., Danzmann, K., de Deus Silva, M., Diepholz, I., Dixon, G., Dolesi, R., Ferraioli, L., Ferroni, V., Fitzsimons, E.D., Flatscher, R., Freschi, M., García, A., Gerndt, R., Gesa, L., Giardini, D., Gibert, F., Giusteri, R., Grimani, C., Grzymisch, J., Guzman, F., Harrison, I., Hartig, M.-S., Heinzel, G., Hewitson, M., Hollington, D., Hoyland, D., Hueller, M., Inchauspé, H., Jennrich, O., Jetzer, P., Johann, U., Johlander, B., Karnesis, N., Kaune, B., Killow, C.J., Korsakova, N., Lobo, J.A., Liu, L., López-Zaragoza, J. P., Maarschalkerweerd, R., Mance, D., Martín, V., Martin-Polo, L., Martin-Porqueras, F., Martino, J., McNamara, P.W., Mendes, J., Mendes, L., Meshksar, N., Monsky, A., Nofrarias, M., Paczkowski, S., Perreur-Lloyd, M., Petiteau, A., Pivato, P., Plagnol, E., Ramos-Castro, J., Reiche, J., Rivas, F., Robertson, D.I., Russano, G., Sanjuan, J., Slutsky, J., Sopuerta, C.F., Steier, F., Sumner, T., Texier, D., Thorpe, J.I., Vetrugno, D., Vitale, S., Wand, V., Wanner, G., Ward, H., Wass, P. J., Weber, W.J., Wissel, L., Wittchen, A., Zweifel, P., Armano, M., Audley, H., Baird, J., Binetruy, P., Born, M., Bortoluzzi, D., Brandt, N., Castelli, E., Cavalleri, A., Cesarini, A., Cruise, A. M., Danzmann, K., de Deus Silva, M., Diepholz, I., Dixon, G., Dolesi, R., Ferraioli, L., Ferroni, V., Fitzsimons, E.D., Flatscher, R., Freschi, M., García, A., Gerndt, R., Gesa, L., Giardini, D., Gibert, F., Giusteri, R., Grimani, C., Grzymisch, J., Guzman, F., Harrison, I., Hartig, M.-S., Heinzel, G., Hewitson, M., Hollington, D., Hoyland, D., Hueller, M., Inchauspé, H., Jennrich, O., Jetzer, P., Johann, U., Johlander, B., Karnesis, N., Kaune, B., Killow, C.J., Korsakova, N., Lobo, J.A., Liu, L., López-Zaragoza, J. P., Maarschalkerweerd, R., Mance, D., Martín, V., Martin-Polo, L., Martin-Porqueras, F., Martino, J., McNamara, P.W., Mendes, J., Mendes, L., Meshksar, N., Monsky, A., Nofrarias, M., Paczkowski, S., Perreur-Lloyd, M., Petiteau, A., Pivato, P., Plagnol, E., Ramos-Castro, J., Reiche, J., Rivas, F., Robertson, D.I., Russano, G., Sanjuan, J., Slutsky, J., Sopuerta, C.F., Steier, F., Sumner, T., Texier, D., Thorpe, J.I., Vetrugno, D., Vitale, S., Wand, V., Wanner, G., Ward, H., Wass, P. J., Weber, W.J., Wissel, L., Wittchen, A., and Zweifel, P.
Abstract: We report on the first subpicometer interferometer flown in space. It was part of ESA's Laser Interferometer Space Antenna (LISA) Pathfinder mission and performed the fundamental measurement of the positional and angular motion of two free-falling test masses. The interferometer worked immediately, stably, and reliably from switch on until the end of the mission with exceptionally low residual noise of 32.0-1.7+2.4 fm/Hz, significantly better than required. We present an upper limit for the sensor performance at millihertz frequencies and a model for the measured sensitivity above 200 mHz.
Published: 2021

49. COVID-19 Network: the response of an Italian Reference Institute to research challenges about a new pandemia

Author: Bosari, S., Scudeller, L., Fusetti, G., Rusconi, L., Dell Orto, S., Prati, D., Valenti, L., Lamorte, G., Manunta, M., Baselli, G., Santoro, L., Gori, A., Bandera, A., Muscatello, A., Mangioni, D., Alagna, L., Bozzi, G., Lombardi, A., Ungaro, R., Itri, T., Ferroni, V., Pastore, V., Massafra, R., Rondolini, I., Peyvandi, F., Gualtierotti, R., Ferrari, B., Rossio, R., Corona, E., Rampi, N., Massimo, C., Montano, N., Vigone, B., Bellocchi, C., Fiorelli, E., Melli, V., Tobaldini, E., Blasi, F., Aliberti, S., Spotti, M., Simonetta, E., Terranova, L., Amati, F., Miele, C., Misuraca, S., D'Adda, A., Della Fiore, S., Di Pasquale, M., Contarini, M.M.M., Ori, M., Morlacchi, L., Rossetti, V., Gramegna, A., Pappalettera, M., Cavallini, M., Vigni, A., Vicenzi, M., Rota, I., Costantino, G., Solbiati, M., Furlan, L., Mancarella, M., Colombo, G., Fanin, A., Monzani, V., Rovellini, A., Barbetta, L., Billi, F., Folli, C., Baldini, M., Motta, I., Scaramellini, N., Fracanzani, A.L., Lombardi, R., Iuculano, F., Cesari, M., Proietti, M., Calcaterra, L., Nobili, A., Tettamanti, M., Monti, I., and Pesenti, A.
Published: 2020
Full Text: View/download PDF

50. Sensor Noise in LISA Pathfinder : In-Flight Performance of the Optical Test Mass Readout

Author: Armano, M., primary, Audley, H., additional, Baird, J., additional, Binetruy, P., additional, Born, M., additional, Bortoluzzi, D., additional, Brandt, N., additional, Castelli, E., additional, Cavalleri, A., additional, Cesarini, A., additional, Cruise, A. M., additional, Danzmann, K., additional, de Deus Silva, M., additional, Diepholz, I., additional, Dixon, G., additional, Dolesi, R., additional, Ferraioli, L., additional, Ferroni, V., additional, Fitzsimons, E. D., additional, Flatscher, R., additional, Freschi, M., additional, García, A., additional, Gerndt, R., additional, Gesa, L., additional, Giardini, D., additional, Gibert, F., additional, Giusteri, R., additional, Grimani, C., additional, Grzymisch, J., additional, Guzman, F., additional, Harrison, I., additional, Hartig, M.-S., additional, Heinzel, G., additional, Hewitson, M., additional, Hollington, D., additional, Hoyland, D., additional, Hueller, M., additional, Inchauspé, H., additional, Jennrich, O., additional, Jetzer, P., additional, Johann, U., additional, Johlander, B., additional, Karnesis, N., additional, Kaune, B., additional, Killow, C. J., additional, Korsakova, N., additional, Lobo, J. A., additional, Liu, L., additional, López-Zaragoza, J. P., additional, Maarschalkerweerd, R., additional, Mance, D., additional, Martín, V., additional, Martin-Polo, L., additional, Martin-Porqueras, F., additional, Martino, J., additional, McNamara, P. W., additional, Mendes, J., additional, Mendes, L., additional, Meshksar, N., additional, Monsky, A., additional, Nofrarias, M., additional, Paczkowski, S., additional, Perreur-Lloyd, M., additional, Petiteau, A., additional, Pivato, P., additional, Plagnol, E., additional, Ramos-Castro, J., additional, Reiche, J., additional, Rivas, F., additional, Robertson, D. I., additional, Russano, G., additional, Sanjuan, J., additional, Slutsky, J., additional, Sopuerta, C. F., additional, Steier, F., additional, Sumner, T., additional, Texier, D., additional, Thorpe, J. I., additional, Vetrugno, D., additional, Vitale, S., additional, Wand, V., additional, Wanner, G., additional, Ward, H., additional, Wass, P. J., additional, Weber, W. J., additional, Wissel, L., additional, Wittchen, A., additional, and Zweifel, P., additional
Published: 2021
Full Text: View/download PDF

Catalog

Books, media, physical & digital resources

See catalog results

Searchworks

Select search scope, currently: Articles Catalog books, media & more in Jio Institute collections Articles journal articles & other e-resources

Search

Search Constraints

Refine your results

Search Limiters

Topic

Publication Year Range

Language

Publication Type

Journal

Database

Publisher

161 results on '"Ferroni V."'

Search Results

Catalog

Select search scope, currently: Articles

Catalog

books, media & more in Jio Institute collections

Articles

journal articles & other e-resources