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1. Cost-effectiveness of robotic vs laparoscopic distal pancreatectomy. Results from the national prospective trial ROBOCOSTES

Author

Guerrero-Ortiz, María Alejandra, Sánchez-Velazquez, Patricia, Burdío, Fernando, Gimeno, Marta, Podda, Mauro, Pellino, Gianluca, Toledano, Miguel, Nuñez, Javier, Bellido, Juan, Acosta-Mérida, María Asunción, Vicente, Emilio, Lopez-Ben, Santiago, Pacheco, David, Pando, Elizabeth, Jorba, Rosa, Trujillo, Juan Pablo Arjona, Ausania, Fabio, Alvarez, Mario, Fernandes, Nair, Castro-Boix, Sandra, Gantxegi, Amaia, Carré, Miquel Kraft-, Pinto-Fuentes, Pilar, Bueno-Cañones, Alejandro, Valdes-Hernandez, Javier, Tresierra, Luis, Caruso, Riccardo, Ferri, Valentina, Tio, Berta, Babiloni-Simon, Sonia, Lacasa-Martin, David, González-Abós, Carolina, Guevara-Martinez, Jenny, Gutierrez-Iscar, Eduardo, Sanchez-Santos, Raquel, Cano-Valderrama, Oscar, Nogueira-Sixto, Manuel, Alvarez-Garrido, Nicolas, Martinez-Cortijo, Sagrario, Lasaia, Manuel Alberto, Linacero, Santiago, Morante, Ana Pilar, Rotellar, Fernando, Arredondo, Jorge, Marti, Pablo, Sabatella, Lucas, Zozaya, Gabriel, and Ielpo, Benedetto

Published
2024
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2. Correction: Cost-efectiveness of robotic vs laparoscopic distal pancreatectomy. Results from the national prospective trial ROBOCOSTES

Author

Guerrero-Ortiz, María Alejandra, Sánchez-Velazquez, Patricia, Burdío, Fernando, Gimeno, Marta, Podda, Mauro, Pellino, Gianluca, Toledano, Miguel, Nuñez, Javier, Bellido, Juan, Acosta-Mérida, María Asunción, Vicente, Emilio, Lopez-Ben, Santiago, Pacheco, David, Pando, Elizabeth, Jorba, Rosa, Trujillo, Juan Pablo Arjona, Ausania, Fabio, Alvarez, Mario, Fernandes, Nair, Castro-Boix, Sandra, Gantxegi, Amaia, Carré, Miquel Kraft-, Pinto-Fuentes, Pilar, Bueno-Cañones, Alejandro, Valdes-Hernandez, Javier, Tresierra, Luis, Caruso, Riccardo, Ferri, Valentina, Tio, Berta, Babiloni-Simon, Sonia, Lacasa-Martin, David, González-Abós, Carolina, Guevara-Martinez, Jenny, Gutierrez-Iscar, Eduardo, Sanchez-Santos, Raquel, Cano-Valderrama, Oscar, Nogueira-Sixto, Manuel, Alvarez-Garrido, Nicolas, Martinez-Cortijo, Sagrario, Lasaia, Manuel Alberto, Linacero, Santiago, Morante, Ana Pilar, Rotellar, Fernando, Arredondo, Jorge, Marti, Pablo, Sabatella, Lucas, Zozaya, Gabriel, and Ielpo, Benedetto

Published
2024
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4. Phase 2, Multicenter, Open-label, Nonrandomized Study of Neoadjuvant Chemotherapy Liposomal Irinotecan With 5-Fluorouracil, Leucovorin, and Oxaliplatin, Followed by Chemoradiotherapy in Patients With Rectal Cancer in a Watch-and-Wait Program

Author

Muñoz, César, Riesco Martinez, María-C., Ugidos, Lisardo, García-Alfonso, Pilar, Alvarez-Gallego, Rafael, Peinado, Paloma, Toledano, Carmen, Mihic-Góngora, Luka, Ortega Anselmi, Justo Gabriel, Sanz Garcia, Enrique, Vicente, Emilio, Quijano, Yolanda, Durán, Hipólito J., Díaz, Eduardo, Ferri, Valentina, Rubio, Carmen, HernandoRequejo, Ovidio, López González, Mercedes, Prados, Susana, López, Ulpiano, Allona, María, PérezDueñas, Virginia, Perez-Escutia, María Angeles, and Cubillo, Antonio

Published
2024
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6. IRON: A retrospective international multicenter study on robotic versus laparoscopic versus open approach in gallbladder cancer

Author

Ielpo, Benedetto, Vittoria d’Addetta, Maria, Burdio, Fernando, Sanchez-Velazquez, Patricia, Vellalta, Gemma, Cremona, Simone, Villamonte, Maria, Morelli, Luca, Furbetta, Niccoló, Di Franco, Gregorio, Comandatore, Annalisa, Mastrangelo, Mattia, Mazzone, Chiara, Masetti, Michele, Offi, Maria Fortuna, Geraldi, Eleonora, Aldrighetti, Luca, Ingallinella, Sara, Ratti, Francesca, Rosso, Edoardo, De Blasi, Vito, Anselmo, Alessandro, Conte, Luigi Eduardo, Memeo, Riccardo, Delvecchio, Antonella, Sukandy, Iswanto, Moraldi, Luca, Grazi, Gian Luca, Spampinato, Marcello G., D'Ugo, Stefano, Heng Chiow, Adrian Kah, Yi Yee, Francis Zheng, Tan, Hiang Jin, Thiruchelvam, Nita, Lancellotti, Francesco, Satyadas, Thomas, Fedi, Massimo, De Vincenti, Rosita, Leo, Francesca, Pesi, Benedetta, Belli, Andrea, Izzo, Francesco, Cutolo, Carmen, Romano, Fabrizio, Scotti, Mauro Alessandro, Carissimi, Francesca, Garancini, Mattia, Ciulli, Cristina, Mazzola, Michele, Ferrari, Giovanni, Zironda, Andrea, Giani, Alessandro, Giuliani, Giuseppe, Federica Dorma, Maria Pia, Guerra, Francesco, Di Marino, Michele, Coratti, Andrea, Mina, Elisa, Romanzi, Andrea, Prieto, Mikel, Perfecto, Arkaitz, Ioannidis, Orestis, Lombardeas, Odysseas, Ardito, Francesco, Giuliante, Felice, Lopez-Lopez, Victor, Robles-Campos, Ricardo, Martinie, John, Mccarron, Frances, Romito, Raffaele, Nicolosi, Filadelfio Massimiliano, Ben Dhaou, Anis, Chamekh, Atef, Rezgui, Bochra, Pacilli, Mario, Pavone, Giovanna, Tartaglia, Nicola, Gupta, Rahul, Grego, Davide Giovanni, Ricci, Claudio, Pata, Francesco, Nardo, Bruno, Facundo, Helena, Guevara, Oscar, Lorenzin, Dario, Guglielmi, Alfredo, Ruzzenente, Andrea, Valle, Valentina, Alberto, Mangano, Giulianotti, PierCristoforo, Vicente, Emilio, Ferri, Valentina, Avella, Pasquale, Calise, Fulvio, Rocca, Aldo, Bianchi, Paolo, Rompianesi, Gianluca, Troisi, Roberto I., Donadon, Matteo, di Martino, Marcello, Podda, Mauro, Pisanu, Adolfo, Torzilli, Guido, Vittoria d'Addetta, Maria, Di Martino, Marcello, and Giulianotti, Pier Cristoforo

Published
2024
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13. Onset and mortality of Parkinson’s disease in relation to type II diabetes

Author

Pezzoli, Gianni, Cereda, Emanuele, Amami, Paolo, Colosimo, Santo, Barichella, Michela, Sacilotto, Giorgio, Zecchinelli, Anna, Zini, Michela, Ferri, Valentina, Bolliri, Carlotta, Calandrella, Daniela, Bonelli, Maria Grazia, Cereda, Viviana, Reali, Elisa, Caronni, Serena, Cassani, Erica, Canesi, Margherita, del Sorbo, Francesca, Soliveri, Paola, Zecca, Luigi, Klersy, Catherine, Cilia, Roberto, and Isaias, Ioannis U.

Published
2023
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14. The Higher Educated, the Lower Paid: The Fixed-Term Wage Penalty within Highly Educated Workers in Italy

Author

Brunetti, Irene, Cirillo, Valeria, and Ferri, Valentina

Abstract

This paper explores the temporary-permanent wage gap experienced by Italian graduate workers. To evaluate the wage gap along the entire wage distribution and account for heterogeneous effects of temporary employment, we apply the Recentered Influence Function (RIF) regression approach. The results suggest that the monthly net wage earned by Italian highly educated workers having a temporary contract is lower than that of their 'permanent' counterparts even after controlling for a plethora of individual and job characteristics. More than 50% of the wage gap is due to unobserved characteristics. The field of study, more than the location of the University, explains this discrimination effect due to contractual arrangement. Although the latter is verified along the entire distribution, major effects arise among high-paid and low-paid jobs depicting a U-shape pattern. Results are robust to self-selection, endogeneity, and gender controls.

Published
2022
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18. Predicting treatment response and survival in rectal cancer: insights from 18 FDG-PET/MRI post-neoadjuvant therapy.

Author

Ferri, Valentina, Vicente, Emilio, Quijano, Yolanda, Duran, Hipolito, Diaz, Eduardo, Fabra, Isabel, Malave, Luis, Ruiz, Pablo, Ballelli, Luca, Broglio, Alessandro, Cañamaque, Lina Garcia, Segui, Andrea Verdu, Dueñas, Virginia Perez, and Caruso, Riccardo

Abstract

Introduction: Accurate identification of patients with pathologic complete response (pCR) following neoadjuvant radiochemotherapy (RCT) for locally advanced rectal cancer (LARC) is essential. 18-FDG PET/MRI provides metabolic information that complements the morphological assessment of standard MRI, potentially enhancing the differentiation between fibrotic and tumorous tissues post-treatment. This study aims to evaluate the performance of 18-FDG PET/MRI in assessing treatment response compared to standard MRI. Materials and methods: A prospective study was conducted at HM Sanchinarro University Hospital, Madrid, from 2018 to 2021. Patients with LARC undergoing RCT were included and staged at diagnosis and restaged 8–12 weeks post-neoadjuvant treatment using 18-FDG PET/MRI. The primary outcome was to compare the performance of PET/MRI and standard MRI in detecting pCR and tumor regression grade (TRG) confirmed via histopathological examination. Quantitative analysis assessed the apparent diffusion coefficient (ADC) and standardized uptake value (SUV). A secondary outcome included survival analysis using the Kaplan–Meier method and Cox regression analysis for radiological and pathological prognostic markers. Results: Among 33 patients, pCR was observed in 45% (14/33). PET/MRI demonstrated sensitivity, specificity, and accuracy values of 0.88, 0.80, and 0.84, respectively, for detecting pCR, compared to 0.82, 0.50, and 0.67 for standard MRI (p < 0.001). PET/MRI accurately identified TRG stages in 72% of cases, compared to 50% for standard MRI. Post-SUV, post-ADC, and delta-ADC were the most precise PET/MRI predictors for pCR, with AUC values of 0.81, 0.75, and 0.55, respectively. Patients with mrEMVI and mrTRG showed worse disease-free survival (DFS). Conclusion: 18-FDG PET/MRI emerges as a promising imaging tool for predicting response to neoadjuvant treatment in rectal cancer, with superior diagnostic accuracy compared to standard MRI. Radiological findings, such as EMVI, can identify high-risk patients, offering valuable prognostic insights. [ABSTRACT FROM AUTHOR]

Published
2025
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19. MIRD Pamphlet No. 31: MIRDcell V4—Artificial Intelligence Tools to Formulate Optimized Radiopharmaceutical Cocktails for Therapy.

Author

Katugampola, Sumudu, Wang, Jianchao, Howell, Roger W., Barbee, Rachel Marie, Bertolet, Alejandro, Bolch, Wesley E., Dewaraja, Yuni K., Erwin, William D., Ferri, Valentina, Ivashchenko, Oleksandra V., Kesner, Adam L., Laforest, Richard, Peterson, Todd E., Rajendran, Joseph G., Sgouros, George, Uribe, Carlos F., and Zanzonico, Pat B.

Published
2024
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20. α-Synuclein Oligomers in Skin Biopsies Predict the Worsening of Cognitive Functions in Parkinson's Disease: A Single-Center Longitudinal Cohort Study.

Author

Contaldi, Elena, Basellini, Milo Jarno, Mazzetti, Samanta, Calogero, Alessandra Maria, Colombo, Aurora, Cereda, Viviana, Innocenti, Gionata, Ferri, Valentina, Calandrella, Daniela, Isaias, Ioannis U., Pezzoli, Gianni, and Cappelletti, Graziella

Subjects
PARKINSON'S disease, MONTREAL Cognitive Assessment, PERIPHERAL nervous system, SKIN biopsy, MINI-Mental State Examination
Abstract

α-synuclein oligomers within synaptic terminals of autonomic fibers of the skin reliably discriminate Parkinson's disease (PD) patients from healthy controls. Nonetheless, the prognostic role of oligomers for disease progression is unknown. We explored whether α-synuclein oligomers evaluated as proximity ligation assay (PLA) score may predict the worsening of cognitive functions in patients with Parkinson's disease. Thirty-four patients with PD and thirty-four healthy controls (HC), matched 1:1 for age and sex, were enrolled. Patients with PD underwent baseline skin biopsy and an assessment of cognitive domains including Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Clock Drawing Test, and Frontal Assessment Battery. At the last follow-up visit available, patients were either cognitively stable (PD-CS) or cognitively deteriorated (PD-CD). α-synuclein oligomers were quantified as PLA scores. Differences between groups were assessed, controlling for potential confounders. The relationship between skin biopsy measures and cognitive changes was explored using correlation and multivariable regression analyses. The discrimination power of the PLA score was assessed via ROC curve. To elucidate the relationship between skin biopsy and longitudinal cognitive measures, we conducted multivariable regression analyses using delta scores of cognitive tests (Δ) as dependent variables. We found that PD-CD had higher baseline PLA scores than PD-CS (p = 0.0003), and they were correctly identified in the ROC curve analysis (AUC = 0.872, p = 0.0003). Furthermore, ANCOVA analysis with Bonferroni correction, considering all groups (PD-CS, PD-CD, and HC), showed significant differences between PD-CS and PD-CD (p = 0.003), PD-CS and HC (p = 0.002), and PD-CD and HC (p < 0.001). In the regression model using ΔMMSE as the dependent variable, the PLA score was found to be a significant predictor (β = −0.441, p = 0.016). Similar results were observed when evaluating the model with ΔMoCA (β = −0.378, p = 0.042). In conclusion, patients with Parkinson's disease with higher α-synuclein burden in the peripheral nervous system may be more susceptible to cognitive decline. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Comparing GBA1‐Parkinson's disease and idiopathic Parkinson's disease: α‐Synuclein oligomers and synaptic density as biomarkers in the skin biopsy.

Author

Mazzetti, Samanta, Contaldi, Elena, Basellini, Milo Jarno, Novello, Claudia, Calogero, Alessandra Maria, Straniero, Letizia, Garrì, Federica, Ferri, Valentina, Calandrella, Daniela, Del Sorbo, Francesca, Asselta, Rosanna, Cereda, Emanuele, Cappelletti, Graziella, Isaias, Ioannis Ugo, and Pezzoli, Gianni

Subjects
PARKINSON'S disease, CLINICAL trials monitoring, NEUROLOGICAL disorders, AUTONOMIC nervous system, SKIN biopsy, SWEAT glands
Abstract

The main genetic risk factors for Parkinson's disease (PD) are presently represented by variants in GBA1 gene encoding for the β‐glucocerebrosidase (GCase). Searching for a peripheral biomarker that can be used for selecting and monitoring patients in clinical trials targeting GBA1‐associated PD (GBA1‐PD) is a current challenge. We previously demonstrated that α‐synuclein oligomers expressed as proximity ligation assay (PLA) score in synaptic terminals of skin biopsy are a reliable biomarker for distinguishing idiopathic PD (iPD) from healthy controls (HC). This cross‐sectional study investigates an unexplored cohort of GBA1‐PD (n = 27) compared to 28 HC, and 36 iPD cases to (i) analyze α‐synuclein oligomers and quantify them throughout PLA score, (ii) investigate GCase expression in brain and synaptic terminals targeting the sweat gland, (iii) unravel indicators that could differentiate patients with specific GBA1 mutations. PLA score discriminates GBA1‐PD from HC with sensitivity = 88.9% (95% CI 70.84–97.65), specificity = 88.5% (95% CI 69.85–97.55), and PPV = 88.9% (95% CI 73.24–95.90), AUC value = 0.927 (95% CI 0.859–0.996). No difference was found between GBA1‐PD patients and iPD, suggesting a common pathological pathway based on α‐synuclein oligomers. GCase score did not differ in GBA1‐PD, iPD, and HC in the synaptic terminals, whereas a positive correlation was found between PLA score and GCase score. Moreover, a significant increase in synaptic density was observed in GBA1‐PD compared to iPD and HC (P < 0.0001). Employing ROC curve to discriminate GBA1‐PD from iPD, we found an AUC value for synaptic density = 0.855 (95% CI 0.749–0.961) with sensitivity = 85.2% (95% CI 66.27%–95.81%), specificity = 77.1% (95% CI 59.86%–89.58%), and PPV = 74.19% (60.53%–84.35%). The highest synaptic density values were observed in p.N409S patients. This work points out to the value of both PLA score and synaptic density in distinguishing GBA1‐PD from iPD and to their potential to stratify and monitor patients in the context of new pathway‐specific therapeutic options. [ABSTRACT FROM AUTHOR]

Published
2024
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22. MIRD Pamphlet No. 30: MIRDfit—A Tool for Fitting of Biodistribution Time–Activity Data for Internal Dosimetry.

Author

Carter, Lukas M., Ocampo Ramos, Juan Camilo, Schuerrle, Seval Beykan, Marquis, Harry, Lassmann, Michael, Bolch, Wesley E., Kesner, Adam L., Adhikarla, Vikram, Barbee, Rachael, Bolch, Wesley, Dewaraja, Yuni, Erwin, William, Ferri, Valentina, Fisher, Darrell, Howell, Roger, Ivaschenko, Oleksandra, Kesner, Adam, Laforest, Richard, Meridith, Ruby, and Rajendran, Joseph

Published
2024
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24. Variation in complications and mortality following ALPPS at early-adopting centers

Author

Wanis, Kerollos N., Linecker, Michael, Madenci, Arin L., Müller, Philip C., Nüssler, Natascha, Brusadin, Roberto, Robles-Campos, Ricardo, Hahn, Oszkar, Serenari, Matteo, Jovine, Elio, Lehwald, Nadja, Knoefel, Wolfram T., Reese, Tim, Oldhafer, Karl, de Santibañes, Martin, Ardiles, Victoria, Lurje, Georg, Capelli, Rafaela, Enne, Marcelo, Ratti, Francesca, Aldrighetti, Luca, Zhurbin, Alexey S., Voskanyan, Sergey, Machado, Marcel, Kitano, Yuki, Adam, René, Chardarov, Nikita, Skipenko, Oleg, Ferri, Valentina, Vicente, Emilio, Tomiyama, Koji, and Hernandez-Alejandro, Roberto

Published
2021
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34. Same-day post-therapy imaging with a new generation whole-body digital SPECT/CT in assessing treatment response to [177Lu]Lu-PSMA-617 in metastatic castration-resistant prostate cancer.

Author

Song, Hong, Leonio, Maria Isabel, Ferri, Valentina, Duan, Heying, Aparici, Carina Mari, Davidzon, Guido, Franc, Benjamin L., Moradi, Farshad, Shah, Jagruti, Bergstrom, Colin P., Fan, Alice C., Shah, Sumit, Khaki, Ali Raza, Srinivas, Sandy, and Iagaru, Andrei

Subjects
CASTRATION-resistant prostate cancer, SINGLE-photon emission computed tomography, COMPUTED tomography, PROGRESSION-free survival, IMAGE analysis
Abstract

Purpose: Lutetium-177 [177Lu]Lu-PSMA-617 radioligand therapy (RLT) represents a significant advancement for metastatic castration-resistant prostate cancer (mCRPC), demonstrating improvements in radiographic progression free survival (rPFS) and overall survival (OS) with a low rate of associated side effects. Currently, most post-therapy SPECT/CT is conducted at 24 h after infusion. This study examines the clinical utility of a next-generation multi-detector Cadmium-Zinc-Telluride (CZT) SPECT/CT system (StarGuide) in same-day post-infusion assessment and early treatment response to [177Lu]Lu-PSMA-617. Methods: In this retrospective study, 68 men with progressive mCRPC treated with [177Lu]Lu-PSMA-617 at our center from June 2022 to June 2023 were evaluated. Digital whole-body SPECT/CT imaging was performed after [177Lu]Lu-PSMA-617infusion (mean ± SD: 1.8 ± 0.6 h, range 1.1–4.9 h). Quantitative analysis of [177Lu]Lu-PSMA-617 positive lesions was performed in patients who underwent at least 2 post-therapy SPECT/CT, using liver parenchyma uptake as reference. Metrics including [177Lu]Lu-PSMA-617 positive total tumor volume (Lu-TTV), SUVmax and SUVmean were calculated. These quantitative metrics on post-infusion SPECT/CT images after cycles 1, 2 and 3 were correlated with overall survival (OS), prostate specific antigen-progression free survival (PSA-PFS) as defined by prostate cancer working group 3 (PCWG3), and PSA decrease over 50% (PSA50) response rates. Results: 56 patients (means age 76.2 ± 8.1 years, range: 60–93) who underwent at least 2 post-therapy SPECT/CT were included in the image analysis. The whole-body SPECT/CT scans (~ 12 min per scan) were well tolerated, with 221 same-day scans performed (89%). At a median of 10-months follow-up, 33 (58.9%) patients achieved PSA50 after [177Lu]Lu-PSMA-617 treatment and median PSA-PFS was 5.0 months (range: 1.0–15 months) while median OS was not reached. Quantitative analysis of SPECT/CT images showed that 37 patients (66%) had > 30% reduction in Lu-TTV, associated with significantly improved overall survival (median not reached vs. 6 months, P = 0.008) and PSA-PFS (median 6 months vs. 1 months, P < 0.001). However, changes in SUVmax or SUVmean did not correlate with PSA-PFS or OS. Conclusion: We successfully implemented same-day post-therapy SPECT/CT after [177Lu]Lu-PSMA-617 infusions. Quantitation of 1–2 h post-therapy SPECT/CT images is a promising method for assessing treatment response. However, the approach is currently limited by its suboptimal detection of small tumor lesions and the necessity of incorporating a third-cycle SPECT/CT to mitigate the effects of any potential treatment-related flare-up. Further investigation in a larger patient cohort and prospective validation is essential to confirm these findings and to explore the role of SPECT/CT as a potential adjunct to PSMA PET/CT in managing mCRPC. [ABSTRACT FROM AUTHOR]

Published
2024
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42. Dietary habits in Parkinson's disease: Adherence to Mediterranean diet

Author

Cassani, Erica, Barichella, Michela, Ferri, Valentina, Pinelli, Giovanna, Iorio, Laura, Bolliri, Carlotta, Caronni, Serena, Faierman, Samanta A., Mottolese, Antonia, Pusani, Chiara, Monajemi, Fatemeh, Pasqua, Marianna, Lubisco, Alessandro, Cereda, Emanuele, Frazzitta, Giuseppe, Petroni, Maria L., and Pezzoli, Gianni

Published
2017
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43. Dietary habits and neurological features of Parkinson's disease patients: Implications for practice

Author

Barichella, Michela, Cereda, Emanuele, Cassani, Erica, Pinelli, Giovanna, Iorio, Laura, Ferri, Valentina, Privitera, Giulia, Pasqua, Marianna, Valentino, Angela, Monajemi, Fatemeh, Caronni, Serena, Lignola, Caterina, Pusani, Chiara, Bolliri, Carlotta, Faierman, Samanta A., Lubisco, Alessandro, Frazzitta, Giuseppe, Petroni, Maria L., and Pezzoli, Gianni

Published
2017
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44. Total and anatomically contextualized quantitative 18 F-DCFPyL PET at biochemical recurrence to predict subsequent biochemical progression-free survival in patients with prostate cancer.

Author

Song, Hong, Anand, Aseem, Sjöstrand, Karl, Ferri, Valentina, Duan, Heying, Shah, Jagruti, Moradi, Farshad, Mari Aparici, Carina, Franc, Benjamin Lewis, Davidzon, Guido, Bergstrom, Colin P, Fan, Alice C., Shah, Sumit, Khaki, Ali Raza, Srinivas, Sandy, and Iagaru, Andrei

Published
2024
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46. Extra‐EU immigrants and labour productivity: New evidence from Italian firms.

Author

Vittori, Claudia, Ricci, Andrea, and Ferri, Valentina

Subjects
LABOR productivity, COST control, IMMIGRANTS, ACCOUNTING firms, BUSINESS enterprises
Abstract

This paper investigates the impact of extra‐EU workers on labour productivity in Italy. To this aim, we take advantage of firm‐level data derived from the Rilevazione Imprese e Lavoro (RIL‐AIDA) surveys merged with the AIDA‐Bureau Van Dijk archive over the period 2007–2015. Using an econometric strategy that accounts for firms' observed heterogeneity and endogeneity issues, we obtain the following results. First, an increase in the share of extra‐EU workers leads to a decline in labour productivity. Second, the relationship between extra‐EU workers and productivity appears to be different between firms located in centre‐north and those in southern regions. Third, the share of extra‐EU workers is also associated with a decline in average wages and sales per employee, even though this effect is less than that observed for productivity. Our findings support the hypothesis that the demand of immigrants arises as a labour cost reduction strategy and hence tends to weaken firms' competitiveness. [ABSTRACT FROM AUTHOR]

Published
2024
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