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3. Sex Differences in Albumin Quotient and Cerebrospinal Fluid Total Protein Content Do Not Depend on Anthropometric Factors.

Author

Castellazzi, Massimiliano, Candeloro, Raffaella, Trevisan, Caterina, Permunian, Samantha, Buscemi, Gaia, Ghisellini, Sara, Negri, Giovanna, Gilli, Giada, Ferri, Caterina, Bellini, Tiziana, Pizzicotti, Stefano, and Pugliatti, Maura

Subjects
CEREBROSPINAL fluid, ALBUMINS, BLOOD-brain barrier, BODY mass index, STATURE
Abstract

(1) Background: Cerebrospinal fluid (CSF)/serum albumin quotient (QAlb) and CSF total protein (TP) are more elevated in males than females, and this has been hypothesised to be due to anthropometric differences between the sexes. This study aimed to investigate QAlb and CSF TP as a function of body height, weight, and body mass index (BMI). (2) Methods: A total of 207 patients were included in the study and analysed blinded to clinical diagnosis. (3) Results: Multivariable linear regressions were run to predict log-transformed Qalb and log-transformed CSF TP value from age, sex, weight, and height (first model) or from age, sex, and BMI (second model). In both models, age (β = 0.004, 95% CI = 0.002 to 0.006) and sex (β = −0.095, 95% CI = −0.169 to −0.021, and β = −0.135, 95% CI = −0.191 to −0.079) were significant predictors for QAlb, but weight, height, and BMI were not. Similarly, age (β = 0.004, 95% CI = 0.003 to 0.006) and sex (β = −0.077, 95% CI = −0.142 to −0.013, and β = −0.109, 95% CI = −0.157 to −0.060) were significant predictors for CSF TP, while anthropometric characteristics were not. No differences in QAlb and CSF TP were found when grouping males and females by BMI status. (4) Conclusions: Our data suggest that anthropometric characteristics could not explain the sex-related differences in QAlb and CSF TP. [ABSTRACT FROM AUTHOR]

Published
2024
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11. The Sexual Dimorphism in Cerebrospinal Fluid Protein Content Does Not Affect Intrathecal IgG Synthesis in Multiple Sclerosis

Author

Castellazzi, Massimiliano, primary, Ferri, Caterina, additional, Tecilla, Ginevra, additional, Huss, André, additional, Crociani, Paola, additional, Desina, Gaetano, additional, Barbella, Gianvito, additional, Piola, Alice, additional, Permunian, Samantha, additional, Senel, Makbule, additional, Leone, Maurizio, additional, Tumani, Hayrettin, additional, and Pugliatti, Maura, additional

Published
2022
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16. Sexual dimorphism in the cerebrospinal fluid total protein content

Author

Castellazzi, Massimiliano, primary, Pizzicotti, Stefano, additional, Lombardo, Ilenia, additional, Alfiero, Sarah, additional, Morotti, Andrea, additional, Pellegatti, Patrizia, additional, Negri, Giovanna, additional, Natali, Lara, additional, Ferri, Caterina, additional, Fainardi, Enrico, additional, Bellini, Tiziana, additional, and Pugliatti, Maura, additional

Published
2020
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18. Airports and air quality: A critical synthesis of the literature | Aeroporti e qualità dell'aria: Una sintesi critica della letteratura scientifica

Author

Cattani, Giorgio, Di Menno Di Bucchianico, Alessandro, Gaeta, Alessandra, Romano, Daniela, Fontana, Luca, Iavicoli, Ivo, Ancona, Carla, Ancona, Laura, Badaloni, Chiara, Cesaroni, Giulia, Bucci, Simone, Golini, Martina N., Mataloni, Francesca, Morciano, Claudio, Salatino, Chelo G., Zirro, Eleonora, Forastiere, Francesco, Barberini, Silvia, Bignardi, Gianmario, Bolignano, Andrea, Briotti, Valerio, Caleprico, Roberta, Damizia, Sesto, Fabozzi, Tina, Piatti, Raffaele, Troiano, Francesco, Sozzi, Roberto, Caricchia, Anna Maria, De Lauretis, Riccardo, Angelini, Francesco, Barnaba, Francesca, Costabile, Francesca, Gobbi, Gian Paolo, Inglessis, Marco, Tancredi, Francesco, Amadasi, Claudia, Cestari, Laura, Dorio, Roberta, Palazzi, Barbara, Zangrando, Dorelia, Simonato, Lorenzo, Sepulcri, Daniele, Arcadi, Celestina, Bandroco, Luisa, Barra, Graziella, Bellone, Fulvia, Carnà, Paolo, Casu, Pierina, Conchedda, Maria, De Fano, Carmela, Di Gilio, Piera, Macario, Antonella, Peritore, Maria, Sapetti, Stefania, Signorile, Luisa, Tempia, Vilma, Ottino, Marina, Chiusolo, Monica, Fogola, Jacopo, Cadum, Ennio, Camerino, Donatella, Consonni, Dario, Pesatori, Angela, Bertazzi, Pier Alberto, Ferri, Caterina, Minniti, Caterina, Nanni, Maddalena, Petri, Davide, Vigotti, Maria Angela, Licitra, Gaetano, Ascari., Elena, Antoniotti, Maria Chiara, Balconi, Lorena, Bonarrigo, Domenico, Stefani, Cristina Degli, Esposito, Aniello, Gambino, Maria, Speziali, Sabina, Pisani, Salvatore, Angius, Silvana, Galbusera, Emanuele, Maggi, Paola, and Pollini, Roberta

Subjects
Models, Air quality, Ground measurements, Airport
Abstract

This work reviewed existing literature on airport related activities that could worsen surrounding air quality; its aim is to underline the progress coming from recent-year studies, the knowledge emerging from new approaches, the development of semi-empiric analytical methods as well as the questions still needing to be clarified. To estimate pollution levels, spatial and temporal variability, and the sources relative contributions integrated assessment, using both fixed point measurement and model outputs, are needed. The general picture emerging from the studies was a non-negligible and highly spatially variable (within 2-3 km from the fence line) airport contribution; even if it is often not dominant compared to other concomitant pollution sources. Results were highly airport-specific. Traffic volumes, landscape and meteorology were the key variables that drove the impacts. Results were thus hardly exportable to other contexts. Airport related pollutant sources were found to be characterized by unusual emission patterns (particularly ultrafine particles, black carbon and nitrogen oxides during take-off); high time-resolution measurements allow to depict the rapidly changing take-off effect on air quality that could not be adequately observed otherwise. Few studies used high time resolution data in a successful way as statistical models inputs to estimate the aircraft take-off contribution to the observed average levels. These findings should not be neglected when exposure of people living near airports is to be assessed.

Published
2014

19. Health Impact Assessment of airport noise on people living nearby six Italian airports

Author

Ancona, Carla, Golini, Martina Nicole, Mataloni, Francesca, Camerino, Donatella, Chiusolo, Monica, Licitra, Gaetano, Ottino, Marina, Pisani, Salvatore, Cestari, Laura, Vigotti, Maria Angela, Davoli, Marina, Forastiere, Francesco, Ancona, Laura, Badaloni, Chiara, Cesaroni, Giulia, Bucci, Simone, Morciano, Claudio, Salatino, Chelo G., Zirro, Eleonora, Barberini, Silvia, Bignardi, Gianmario, Bolignano, Andrea, Briotti, Valerio, Caleprico, Roberta, Damizia, Sesto, Fabozzi, Tina, Piatti, Raffaele, Troiano, Francesco, Sozzi, Roberto, Caricchia, Anna Maria, De Lauretis, Riccardo, Di Menno Di Bucchianico, Alessandro, Gaeta, Alessandra, Romano, Daniela, Cattani, Giorgio, Angelini, Francesco, Barnaba, Francesca, Costabile, Francesca, Gobbi, Gian Paolo, Fontana, Luca, Iavicoli, Ivo, Inglessis, Marco, Tancredi, Francesco, Amadasi, Claudia, Dorio, Roberta, Palazzi, Barbara, Zangrando, Dorelia, Simonato, Lorenzo, Sepulcri, Daniele, Arcadi, Celestina, Bandroco, Luisa, Barra, Graziella, Bellone, Fulvia, Carnà, Paolo, Casu, Pierina, Conchedda, Maria, De Fano, Carmela, Di Gilio, Piera, Macario, Antonella, Peritore, Maria, Sapetti, Stefania, Signorile, Luisa, Tempia, Vilma, Fogola, Jacopo, Cadum, Ennio, Consonni, Dario, Pesatori, Angela, Bertazzi, Pier Alberto, Ferri, Caterina, Minniti, Caterina, Nanni, Maddalena, Petri, Davide, Ascari, Elena, Antoniotti, Maria Chiara, Balconi, Lorena, Bonarrigo, Domenico, Stefani, Cristina Degli, Esposito, Aniello, Gambino, Maria, Speziali, Sabina, Angius, Silvana, Galbusera, Emanuele, Maggi, Paola, Pollini, Roberta, Ancona, C., Golini, M. N., Mataloni, F., Camerino, D., Chiusolo, M., Licitra, G., Ottino, M., Pisani, S., Cestari, L., Vigotti, M. A., Davoli, M., Forastiere, F., Ancona, L., Badaloni, C., Cesaroni, G., Bucci, S., Morciano, C., Salatino, C. G., Zirro, E., Barberini, S., Bignardi, G., Bolignano, A., Briotti, V., Caleprico, R., Damizia, S., Fabozzi, T., Piatti, R., Troiano, F., Sozzi, R., Caricchia, A. M., De Lauretis, R., Di Menno Di Bucchianico, A., Gaeta, A., Romano, D., Cattani, G., Angelini, F., Barnaba, F., Costabile, F., Gobbi, G. P., Fontana, L., Iavicoli, Ivo, Inglessis, M., Tancredi, F., Amadasi, C., Dorio, R., Palazzi, B., Zangrando, D., Simonato, L., Sepulcri, D., Arcadi, C., Bandroco, L., Barra, G., Bellone, F., Carna, P., Casu, P., Conchedda, M., De Fano, C., Di Gilio, P., Macario, A., Peritore, M., Sapetti, S., Signorile, L., Tempia, V., Fogola, J., Cadum, E., Consonni, D., Pesatori, A., Bertazzi, P. A., Ferri, C., Minniti, C., Nanni, M., Petri, D., Ascari, E., Antoniotti, M. C., Balconi, L., Bonarrigo, D., Stefani, C. D., Esposito, A., Gambino, M., Speziali, S., Angius, S., Galbusera, E., Maggi, P., and Pollini, R.

Subjects
Annoyance, Health impact assessment, Hypertension, Sleep disturbances, Aircraft noise
Abstract

BACKGROUND: aircraft noise has been associated with several health effects. Because of the great success of low-cost flights, small airports have been turned into international airports thus exposing nearby residents to an increase in noise levels and potential disturbances and health disorders. OBJECTIVE: to estimate the exposure levels and evaluate the health impact of aircraft noise on residents nearby six airports in Italy (Rome: Ciampino; Milan: Linate and Malpensa; Pisa; Turin; Venice) focusing on hypertension, acute myocardial infarction (AMI), annoyance and sleep disturbances. METHODS: residents in the local Municipalities considered at 31.12.2010 were included in the study and their addresses were geocoded. Aircraft noise exposure in 2011 was defined using the Integrated Noise Model linked to each participant s address. Lden (55dB were considered: 55,915 (76.3%) were exposed to 55-60 dB; 16,562 (22.6%) to 60-65 dB; 795 (1.2%) to 65-70 dB. Exposure to aircraft noise levels above 55 dB was estimated to be responsible each year of 4,607 (95%CI 0-9,923) additional cases of hypertension; 3.4 (95%CI 0-10.7) cases of AMI; 9,789 (95%CI 6,895-11,962) cases of annoyance; 5,084 (95%CI 1,894-10,509) cases of sleep disturbances. CONCLUSIONS: a significant impact of airport noise on the health of residents nearby six Italian airports was estimated. Epidemiological evaluation and noise mitigation measures should be introduced to protect the health of residents.

Published
2014

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