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Your search keyword '"Ferreira, Natália R."' showing total 7 results
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7 results on '"Ferreira, Natália R."'

2. The Contribution of Endogenous Modulatory Systems to TMS- and tDCS-Induced Analgesia: Evidence from PET Studies

Author

DosSantos, Marcos F., Oliveira, Aleli T., Ferreira, Natália R., Carvalho, Antônio C. P., and Rosado de Castro, Paulo Henrique

Subjects
Article Subject
Abstract

Chronic pain is an important public health issue. Moreover, its adequate management is still considered a major clinical problem, mainly due to its incredible complexity and still poorly understood pathophysiology. Recent scientific evidence coming from neuroimaging research, particularly functional magnetic resonance (fMRI) and positron emission tomography (PET) studies, indicates that chronic pain is associated with structural and functional changes in several brain structures that integrate antinociceptive pathways and endogenous modulatory systems. Furthermore, the last two decades have witnessed a huge increase in the number of studies evaluating the clinical effects of noninvasive neuromodulatory methods, especially transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), which have been proved to effectively modulate the cortical excitability, resulting in satisfactory analgesic effects with minimal adverse events. Nevertheless, the precise neuromechanisms whereby such methods provide pain control are still largely unexplored. Recent studies have brought valuable information regarding the recruitment of different modulatory systems and related neurotransmitters, including glutamate, dopamine, and endogenous opioids. However, the specific neurocircuits involved in the analgesia produced by those therapies have not been fully elucidated. This review focuses on the current literature correlating the clinical effects of noninvasive methods of brain stimulation to the changes in the activity of endogenous modulatory systems.

Published
2018
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3. The efficacy of transcranial direct current stimulation and transcranial magnetic stimulation for chronic orofacial pain: A systematic review

Author

Ferreira, Natália R., primary, Junqueira, Ygor N., additional, Corrêa, Nathália B., additional, Fonseca, Estevão O., additional, Brito, Nathália B. M., additional, Menezes, Thayná A., additional, Magini, Márcio, additional, Fidalgo, Tatiana K. S., additional, Ferreira, Daniele M. T. P., additional, de Lima, Rodrigo L., additional, Carvalho, Antônio C., additional, and DosSantos, Marcos F., additional

Published
2019
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6. A 70-year-old man with severe deep paroxysmal ear pain

Author

Oliveira, Aleli T., primary, Ferreira, Natália R., additional, Marques, Marise P.C., additional, Cunha, Ricardo, additional, Bahia, Paulo R.V., additional, Carvalho, Antônio C.P., additional, DosSantos, Marcos F., additional, and Monteiro, André A., additional

Published
2017
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7. Noninvasive transcranial brain stimulation in central post-stroke pain: A systematic review.

Author

Mayor RS, Ferreira NR, Lanzaro C, Castelo-Branco M, Valentim A, Donato H, and Lapa T

Subjects
Humans, Randomized Controlled Trials as Topic, Pain Management methods, Stroke complications, Stroke therapy, Transcranial Direct Current Stimulation methods, Transcranial Magnetic Stimulation methods
Abstract

Background: The aim of this systematic review is to analyze the efficacy of noninvasive brain stimulation (NBS) in the treatment of central post-stroke pain (CPSP)., Methods: We included randomized controlled trials testing the efficacy of transcranial magnetic stimulation (TMS) or transcranial direct current stimulation versus placebo or other usual therapy in patients with CPSP. Articles in English, Portuguese, Spanish, Italian, and French were included. A bibliographic search was independently conducted on June 1, 2022, by two authors, using the databases MEDLINE (PubMed), Embase (Elsevier), Cochrane Central Register of Controlled Trials (CENTRAL), Scopus, and Web of Science Core Collection. The risk of bias was assessed using the second version of the Cochrane risk of bias (RoB 2) tool and the certainty of the evidence was evaluated through Grading of Recommendations Assessment, Development and Evaluation., Results: A total of 2,674 records were identified after removing duplicates, of which 5 eligible studies were included, involving a total of 119 patients. All five studies evaluated repetitive TMS, four of which stimulated the primary motor cortex (M1) and one stimulated the premotor/dorsolateral prefrontal cortex. Only the former one reported a significant pain reduction in the short term, while the latter one was interrupted due to a consistent lack of analgesic effect., Conclusion: NBS in the M1 area seems to be effective in reducing short-term pain; however, more high-quality homogeneous studies, with long-term follow-up, are required to determine the efficacy of this treatment in CSPS., (© 2024 the author(s), published by De Gruyter.)

Published
2024
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