286 results on '"Ferrario, E"'
Search Results
2. Improvement of LPBF processability of equiatomic MoNbTaTiZr RHEA powder by in-situ precipitation of boride particles
- Author
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Carlucci, G., Fiocchi, J., Ferrario, E., Biffi, C.A., and Casati, R.
- Published
- 2024
- Full Text
- View/download PDF
3. NADase from Aspergillus fumigatus with replaced C-terminus from Neurospora crassa
- Author
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Kallio, J.P., primary, Ferrario, E., additional, Stromland, O., additional, and Ziegler, M., additional
- Published
- 2023
- Full Text
- View/download PDF
4. NADase from Aspergillus fumigatus with mutated calcium binding motif (D219A/E220A)
- Author
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Kallio, J.P., primary, Ferrario, E., additional, Stromland, O., additional, and Ziegler, M., additional
- Published
- 2023
- Full Text
- View/download PDF
5. Bootstrapped Artificial Neural Networks for the seismic analysis of structural systems
- Author
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Ferrario, E., Pedroni, N., Zio, E., and Lopez-Caballero, F.
- Published
- 2017
- Full Text
- View/download PDF
6. Evaluation of the robustness of critical infrastructures by Hierarchical Graph representation, clustering and Monte Carlo simulation
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Ferrario, E., Pedroni, N., and Zio, E.
- Published
- 2016
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- View/download PDF
7. Assessing nuclear power plant safety and recovery from earthquakes using a system-of-systems approach
- Author
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Ferrario, E. and Zio, E.
- Published
- 2014
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- View/download PDF
8. Goal Tree Success Tree–Dynamic Master Logic Diagram and Monte Carlo simulation for the safety and resilience assessment of a multistate system of systems
- Author
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Ferrario, E. and Zio, E.
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- 2014
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- View/download PDF
9. Crystal structure of human trans-3-Hydroxy-L-proline dehydratase
- Author
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Ferrario, E., primary, Miggiano, R., additional, Rizzi, M., additional, and Ferraris, D.M., additional
- Published
- 2022
- Full Text
- View/download PDF
10. A framework for the system-of-systems analysis of the risk for a safety-critical plant exposed to external events
- Author
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Zio, E. and Ferrario, E.
- Published
- 2013
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- View/download PDF
11. Application of metamodel-based techniques for the efficient seismic analysis of structural systems
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Ferrario, E, primary, Pedroni, N, additional, Zio, E, additional, and Lopez-Caballero, F, additional
- Published
- 2015
- Full Text
- View/download PDF
12. Ticagrelor in patients with diabetes and stable coronary artery disease with a history of previous percutaneous coronary intervention (THEMIS-PCI): a phase 3, placebo-controlled, randomised trial
- Author
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Bhatt, D, Steg, P, Mehta, S, Leiter, L, Simon, T, Fox, K, Held, C, Andersson, M, Himmelmann, A, Ridderstrale, W, Chen, J, Song, Y, Diaz, R, Goto, S, James, S, Ray, K, Parkhomenko, A, Kosiborod, M, Mcguire, D, Harrington, R, Santos, V, Jain, A, Lendel, I, Russo, M, Haught, W, Bouza, M, Gogia, H, Banerjee, S, Kichura, G, Kantaros, L, Padron, F, Passi, R, Stone, J, Pursley, M, D'Urso, M, Gardner, T, Bennett, J, Nour, K, Saini, S, Zhang, W, Kumbhani, D, Thomas, D, Angiolillo, D, Bertolet, B, Roman-Miranda, A, Black, R, Manshadi, R, Vaca, C, Blanco, A, Napoli, M, Brabham, D, Akyea-Djamson, A, Desai, P, Prasada, S, Khaira, A, Forgosh, L, Lieber, I, Umpierrez, G, Singal, D, Londono, J, Fraser, N, Ruiz, J, Vega, D, Rodriguez, L, Brown, C, Syed, F, Aggarwala, G, Eaves, W, Foster, M, Gupta, D, Avino, D, Asfour, W, Tonnessen, G, Zhao, X, Singh, N, Brockmyre, A, Lepor, N, Shammas, N, Blick, D, Hearne, S, Prodafikas, J, Carell, E, Izzo, M, Karim, A, Zakhary, B, Atieh, M, Leichter, S, Meadows, C, Hotchkiss, D, Abu-Fadel, M, Wiseman, A, Bander, J, Shah, M, Ganim, R, Sopko, K, Khan, M, Lloret, R, Weirick, T, Mehta, R, Thadani, U, Bhargava, A, Moya, J, Staniloae, C, Guerra, Y, Chhabra, A, Kosmicki, D, Shaheen, W, Mohammed, A, Bitters, J, Pattanayak, J, Javier, J, Srivastava, S, Phillips, R, Al-Amin, J, Lillestol, M, Simpson, P, Hazan, L, Amin, A, Shah, G, Korpas, D, Platt, B, Dickert, J, Puente, O, Hiotis, L, Doyle, T, Rajan, R, Meholick, A, Gring, C, Hage-Korban, E, Feldman, R, Colfer, H, Butman, S, Hart, T, Huling, R, Eshaghian, S, Quintana, O, Cheung, D, Handel, F, Rodriguez, M, Suh, D, Gordon, P, Pressman, G, Bauer, M, French, W, Barettella, M, Chatrathi, S, Suresh, D, Goldberg, R, Huth, M, Younis, L, Rahman, A, Mascolo, R, Welch, M, Suneja, R, Smith, S, Shurmur, S, Agaiby, J, Jingo, A, Johnston, J, Beth, M, Vlastaris, A, Kemp, S, Taheri, H, Pereira, E, Deyoung, M, Hawa, Z, Smith, R, Galski, T, Garas, S, Reddy, M, Sharma, S, Hargrove, J, Treasure, C, Emerson, R, Haddad, T, Rohr, K, Levinson, L, Gaona, R, Uretsky, B, Maheshwari, H, Lee, D, Kinnaman, S, Singal, R, Geohas, J, Gigliotti, O, Raisinghani, A, Khurana, C, Hella, B, Kelberman, M, Voyce, S, Singh, S, Lo, E, Singh, P, Goodfellow, R, Fischer, S, Lorraine, R, Turner, T, Shanes, J, Busch, R, Broker, R, Zaniewski, M, Pounds, K, Debs-Perez, G, Ong, S, Frandsen, B, Fullington, D, Jaffrani, N, Khan, A, Lee, M, Pouzar, J, Revtyak, G, Gonzalez, J, Nakhle, S, Murillo, A, Young, D, Makam, S, Syed, M, Woolf, K, Grena, P, Alfata, S, Mahal, S, Hoffman, D, Kizhakekuttu, T, Deering, J, Bhavsar, J, Mikesell, S, Wilson, W, Wilson, V, El, S, Spinale, F, Kannarkat, V, Rao, S, Hanson, L, Bertsch, J, Gonzalez-Ortiz, E, Severino, N, Willis, J, Schock, J, Bakhtari, L, Gazmuri, R, Ansari, S, Hall, J, Mehta, A, Shealy, N, Zarich, S, Singh, D, Vora, K, Andrawis, N, Molter, D, Maron, D, Cardona, J, D'Agostino, R, Arshad, T, Samaan, R, Jones, D, Presser, D, Heath, J, Green, S, Bittar, G, Henry, S, Korn, D, Schmedtje, J, Nadar, V, Graham, B, Labroo, A, Clavijo, L, Roseman, H, Ledesma, G, Rosen, R, Dor, I, Kirby, W, Sutton, J, Eder, F, Iteld, B, Gomez-Cortes, J, Buchbinder, M, Kasper, J, Terrelonge, A, Torres, G, Jagielo, T, Alvarez, J, Handelsman, Y, Guillen, M, Richwine, R, Lewy-Alterbaum, L, Corder, C, Arvind, M, Bolshoun, D, Mikhail, M, Minton, S, Alvarado, O, Abbott, J, Cauthen, B, Welter, R, Mintz, R, Cox, J, Quick, A, Weiss, M, Dy, J, Zebrack, J, Gandelman, G, Hegde, V, Silver, M, Degregorio, M, Lawson, W, Paa, C, Bortnick, A, Krolick, M, Sotolongo, R, Cheirif, J, Kumar, P, Jetty, P, Patel, A, Kruk, M, Kobielusz-Gembala, I, Rewerska, B, Madrzejewski, A, Milewski, K, Cygler, J, Petryka-Mazurkiewicz, J, Jastrzebski, W, Korecki, J, Fil, W, Prokopczuk, J, Bochenek, A, Wujkowski, M, Witek, R, Konczakowski, P, Miekus, P, Szczasny, M, Musial, W, Cymerman, K, Lampart, J, Mikosinski, J, Szynal, S, Fares, I, Opolski, G, Mazur, S, Wozakowska-Kaplon, B, Bijata-Bronisz, R, Wierucki, L, Losa, B, Drelich, G, Konieczny, M, Starczewski, P, Pawlowicz, L, Jesionowski, P, Jurowiecki, J, Gniot, J, Czyzycki, M, Stania, K, Kucharczyk-Bauman, I, Busz-Papiez, B, Karczmarczyk, A, Sudnik, W, Koszek, A, Kolodziej, P, Skwarna, B, Jaramillo, N, Jankowski, M, Czochra, W, Kinasz, L, Miklaszewicz, B, Stasinska, T, Pluta, W, Basiak, M, Rusicka, T, Niedbal-Yahfouf, I, Popenda, G, Korzeniak, R, Mirek, A, Mariankowski, R, Wojnowski, L, Korol, M, Baszak, J, Podolec, P, Piesiewicz, W, Zurakowski, A, Luengas, C, Skura, M, Pilecki, P, Majchrzak, P, Krzyzagorska, E, Drozd, M, Kaczmarek, B, Sliwinska, T, Zelazowska, K, Sztembis, R, Landa, K, Matyszczak-Toniak, L, Strojek, K, Piepiorka, M, Malinowski, R, Gorska, M, Stolarczyk-Sowa, E, Romanowski, L, Zinka, E, Reszka, Z, Skierkowska, J, Uzunow, A, Laskowska-Derlaga, E, Puntus, E, Kosmacheva, E, Koziolova, N, Pavlov, P, Supryadkina, T, Didenko, Y, Kopylov, P, Kazakov, A, Aksentiev, S, Vishneva, E, Repin, A, Smolenskaya, O, Mantserova, O, Khrustalev, O, Privalova, E, Konstantinov, V, Boldueva, S, Ezhov, A, Chernyavsky, A, Kamalov, G, Galyavich, A, Zubeeva, G, Nechaeva, G, Shustov, S, Dzhaiani, N, Treshkur, T, Osokina, N, Panov, A, Shutemova, E, Makukhin, V, Kropotina, T, Tsyba, L, Karpov, Y, Sizova, J, Ballyuzek, M, Tarasov, N, Demchenko, E, Barbarash, O, Moiseev, V, Markov, V, Kuznetsov, V, Viktorova, I, Sergienko, I, Ermoshkina, L, Khasanov, N, Khlevchuk, T, Baglikov, A, Shalaev, S, Zonova, E, Reznik, E, Haisheva, L, Morugova, T, Lomakin, N, Vishnevsky, A, Shvarts, Y, Magnitskaya, O, Mikhailusova, M, Pavlysh, E, Libov, I, Zateyschikova, A, Kostenko, V, Edin, A, Khovaeva, Y, Zakharov, K, Stryuk, R, Khirmanov, V, Kanorskiy, S, Yakushin, S, Barabashkina, A, Li, H, Zhao, Q, Zhang, J, Ma, J, He, Y, Luo, M, Zhang, A, Zhang, N, Chai, Y, Ma, G, Wang, H, Liu, Z, He, L, Song, Z, Dong, X, Tao, L, Li, Z, Su, X, Kong, X, Niu, H, Ge, J, Luo, Z, Huang, W, Peng, D, Yuan, Z, Milanova, M, Tenev, D, Gogov, A, Karageorgiev, D, Kolchev, T, Rusev, N, Georgieva, N, Kondov, R, Rusinov, V, Petrov, I, Stanchev, G, Konteva, M, Dincheva, A, Yaneva, Z, Vatova, R, Ilieva, K, Runev, N, Kolomanov, B, Iliev, N, Tisheva, S, Chompalova, B, Tokmakova, M, Raev, D, Byanov, K, Markov, D, Mihov, L, Mihov, A, Milcheva, N, Minchev, M, Mollov, M, Borisov, B, Tihchev, T, Karakolev, V, Dimov, B, Georgiev, S, Smilov, L, Koo, B, Ahn, T, Hong, S, Yoon, J, Oh, S, Jeong, M, Kim, D, Chang, K, Kim, W, Hahn, J, Cha, K, Lee, J, Choi, S, Nam, C, Chae, I, Park, Y, Tahk, S, Shin, W, Chae, J, Kim, B, Bae, J, Park, W, Rha, S, Choi, Y, Hwang, J, Park, H, Baracioli, L, Guimaraes, F, Vasconcellos, E, Saraiva, J, Pereira, A, Santos, Q, Rossi, P, Maia, L, Madeira, M, Pereira, M, Botelho, R, Reis, G, Eliaschewitz, F, Borges, J, Nascimento, C, Fortes, J, de Souza, W, Pimentel, P, Hissa, M, Franchetti, M, Precoma, D, Ortiz, C, Hernandes, M, Saporito, W, dos Santos, F, Kormann, A, Neuenschwander, F, Dutra, O, Rassi, N, Tanajura, L, Souza, J, Junior, D, Leaes, P, Forte, A, Bonansea, T, Marin, J, Machado, B, Cerqueira, M, Silva, F, Michalaros, Y, Manenti, E, Cercato, C, Figueiredo, E, Liu, M, Wang, Y, Lee, T, Fang, C, Wu, Y, Ueng, K, Sheu, H, Lai, W, Hsieh, I, Chen, Z, Chiang, C, Shyu, K, Hsia, C, Mar, G, Chan, S, Wu, C, Tseng, W, Yeh, H, Wang, J, Hou, C, Sorokina, I, Dolzhenko, M, Horoshko, O, Karpenko, O, Rudenko, L, Vakaliuk, I, Kulyk, A, Levchenko, O, Prokhorov, O, Reshotko, D, Sorokivskyy, M, Velichko, N, Maslovskyi, V, Teliatnikova, Z, Dotsenko, S, Krakhmalova, O, Kraiz, I, Zharinova, V, Bula, L, Kaydashev, I, Molodtsov, V, Rasputina, L, Pidlisna, V, Lysunets, O, Kravchenko, A, Glushko, L, Khomazyuk, T, Svyshchenko, Y, Parkhomenko, O, Mankovsky, B, Abrahamovych, O, Yagensky, A, Stanislavchuk, M, Vasilyeva, L, Sokolova, L, Sychov, O, Tseluyko, V, Kyrychenko, I, Rishko, M, Furkalo, S, Gallo, R, Bertrand, O, Constance, C, Sussex, B, Zadra, R, Kouz, S, Chehayeb, R, Pandey, A, Dion, D, Bailey, G, Hill, L, Ramanathan, K, Dorsch, M, Nanji, A, Babapulle, M, Montigny, M, Gosselin, G, Dehghani, P, Rupka, D, Le May, M, Pichette, F, St-Maurice, F, Teefy, P, Mansour, S, Kassam, S, Cheung, S, Siega, A, O'Keefe, D, Sabbah, E, Bell, A, Chouinard, G, Wong, B, Miller, M, Gaudet, D, Lachance, P, Bata, I, Petrella, R, Gossard, D, Dumas, R, Ing, D, Boyrazian, H, Bessoudo, R, Huynh, T, Hart, R, Belle-Isle, J, Shukla, D, Kelly, A, Mazza, G, Cha, J, Henein, S, Frechette, A, Vizel, S, Liutkus, J, O'Mahony, M, Halperin, F, Kooy, J, Graham, J, Bailey, A, Wojcik, R, Wilderman, I, Turi, T, Motyovszki, A, Merkely, B, Kiss, R, Kiraly, C, Andrassy, P, Sarszegi, Z, Fulop, T, Zilahi, Z, Edes, I, Papp, A, Muller, G, Czigany, A, Zolyomi, S, Koranyi, L, Takacs, J, Juhasz, F, Benczur, B, Kancz, S, Foldi, A, Nagy, A, Bakai, J, Greschik, I, Puski, L, Nagy, L, Kirschner, R, Kuchar, R, Hajek, P, Busak, L, Michalik, D, Matyasek, I, Marusincova, I, Kucera, D, Jerabek, O, Honkova, M, Dedek, V, Rihacek, I, Kos, P, Slaby, J, Machkova, M, Zidkova, E, Elbl, L, Grunfeldova, H, Carda, J, Mrozek, V, Maly, J, Milkovic, R, Malecha, J, Skalicka, H, Oral, I, Krcova, E, Lisa, L, Belohlavek, J, Miklik, R, Cermak, O, Bednarova, J, Peroutka, Z, Spinar, J, Wilke, A, Appel, K, Taggeselle, J, Forster, A, Toursarkissian, N, Schmidt, E, Bott, J, Al-Zoebi, A, Hennig, D, Schon, N, Sauter, J, Simonis, G, Nischik, R, Rieker, W, Schenkenberger, I, Behnke, T, Klausmann, G, Jeserich, M, Trenk, D, Weigmann, I, Reuter, H, Rummel, R, von Munchhausen, C, von Engelhardt, C, Horibe, E, Shibasaki, T, Sato, T, Kakuta, T, Michishita, I, Tan, M, Ishiki, R, Aoyama, T, Higashiue, S, Niijima, Y, Idogaki, A, Hasegawa, T, Kiyosue, A, Tomobuchi, Y, Kawamitsu, K, Kawasaki, S, Hata, Y, Fukui, K, Seki, K, Takenaka, T, Abe, M, Utsu, N, Oono, A, Mitsuo, K, Sueyoshi, A, Hirohata, A, Tsujimoto, M, Ueda, O, Takase, S, Suzuki, M, Sakuragi, S, Yamamoto, F, Fujimoto, N, Kakinoki, S, Sugiura, T, Sugino, H, Nakamura, T, Kadokami, T, Uehara, H, Ono, M, Yokoya, K, Koike, A, Komatsu, S, Sonoda, M, Ueno, H, Doi, T, Takagi, Y, Fujimoto, K, Eki, Y, Okubo, M, Sasaki, K, van Eck, M, Ronner, E, The, S, van de Wal, R, Nierop, P, de Nooijer, C, Werner, H, Westendorp, I, van der Zwaan, C, Crijns, H, Cornel, J, Strikwerda, S, Bos, R, de Melker, E, Kuijper, A, Louwerenburg, H, Plomp, J, Dantzig, J, Prins, F, van Kesteren, H, Willems, F, Amoroso, G, Carnero, G, Duronto, E, Besada, D, Chacon, C, Zangroniz, P, Solis, S, Liberman, A, Sernia, V, Alvarisqueta, A, Maffei, L, Vilamajo, O, Garcia, C, Sicer, M, Muntaner, J, Bordonava, A, Albisu, J, Zanini, A, Rista, L, Hominal, M, Estrada, J, Prado, A, Gosparini, D, Schiavi, B, Castillo, A, Martinez, G, Lopez, V, Rosas, E, Lopez, G, Cantu, E, de los Rios Ibarra, M, Padilla, F, Carrasco, J, Carrillo, L, Garcia, J, Askar, A, Salinas, C, Gamba, M, Sanchez, C, Cantu, A, Sanchez, R, Madrigal, J, Urbano, R, Romo, A, Gonzalez Juanatey, J, Racugno, P, Fillat, A, de la Torre Hernandez, J, Pelaez, J, Cortada, J, Pavia, P, Navarro, M, Asenjo, R, Diaz, F, Peligero, E, Manterola, F, Ortiz, A, Mediavilla Garcia, J, Ortuno, F, Vera, T, Gonzalez, A, Vinas, J, Fernandez Portales, F, Mayordomo, P, Ojeda, F, Dominguez, A, Gonzalez, R, Guerrero, D, Ruiz Nodar, J, Marimon, X, Margaez, J, Aguilera, R, Diaz Fernandez, J, Zamorano Gomez, J, Gonzalez, V, del Blanco, B, Perez, I, Moreno, M, Ereno, A, Garcia Lledo, J, Prieto, J, Villablanca, A, Raffo, C, Pincetti, C, Conejeros, C, Roman, O, Varleta, P, Goldberg, C, Sandoval, J, Arriagada, G, Corbalan, R, Leon, L, Potthoff, S, Cobos, J, Figueroa, C, Makotoko, E, Fourie, N, Burgess, L, Nortje, H, Theron, R, Pillai, P, Ranjith, N, Trokis, J, Pillay, S, Reddy, J, Nunkoo, T, Kapp, C, Urbach, D, Distiller, L, Horak, A, van Zyl, L, Coetzee, K, Punt, Z, Bayat, J, Dawood, S, Mitha, I, Padayachee, T, Hoosen, F, Dalby, A, Prabhavathi, Gowdaiah, P, Mehta, V, Chag, M, Gadkari, M, Ramamurthee, K, Das, A, Sawhney, J, Sathe, P, Adhyapak, S, Nguyen, T, Pham, V, Do, H, Nguyen, A, Nguyen, H, Truong, B, Jamil-Copley, S, Lang, C, Pell, A, Zaman, A, Storey, R, Swanson, N, Sharman, D, Braganza, D, Hammond, P, Moriarty, A, Bain, S, Pye, M, Sharp, A, Blagden, M, Randeva, H, Myhill, T, Viswanathan, G, Keeling, P, Clifford, P, Saxena, M, Lyons, K, Mcmurray, J, Jaafar, F, Murphy, C, Cartwright, S, Abouglila, K, Antalik, L, Krajci, P, Urban, M, Fazekas, F, Pella, D, Koleny, D, Vykoukalova, T, Macek, V, Vinanska, D, Jamriskova, L, Such, S, Fulop, P, Farsky, S, Bugan, V, Strbova, J, Micko, K, Palka Jr, J, Sivak, V, Kristensen, D, Refsgaard, J, Holmvang, L, Dixen, U, Nielsen, H, Egstrup, K, Jensen, L, Sykulski, R, Rasmussen, O, Andries, A, Luckow, A, Nielsen, G, Sorensen, T, Wongvipaporn, C, Chamnarnphol, N, Srimahachota, S, Sansanayudh, N, Kuanprasert, S, Tresukosol, D, Sookananchai, B, Kanadasi, M, Ozcan, T, Kucuk, M, Ongen, Z, Okuyan, E, Arat, A, Acikel, S, Yalcin, A, Guray, U, Ceyhan, C, Ozer, N, Arslan, S, Angeras, O, Johnston, N, Weiderman, A, Bandh, S, Hansen, O, Larnefeldt, H, Kusiak, D, Lindholm, C, Hedman, A, Erlinge, D, Curiac, D, Lundman, P, Zucconi-Mazzini, R, Aladellie, L, Jensen, J, Verwerft, J, Vrolix, M, Faes, D, Striekwold, H, Sinnaeve, P, Timmermans, P, Guedes, A, Delforge, M, Nimmegeers, J, Stammen, F, Buysschaert, I, Hoffer, E, Hollanders, G, Vervoort, G, Coussement, P, de Maeseneire, S, Janssens, L, Gravdal, S, Risberg, K, Gullestad, L, Hofseth, O, Nilsen, D, Lappegard, K, van den Heuvel, C, Gibbs, C, Khusrawi, A, Arora, S, Tomala, T, Kjaernli, T, Berg-Johansen, J, Hagemeier, R, Skjelvan, G, Colquhoun, D, Amerena, J, Morbey, C, Hammett, C, Dart, A, Lehman, R, Hamilton, A, Worthley, M, Purnell, P, Whelan, A, Macisaac, R, Arya, K, Linjawi, S, Proietto, J, Prasad, L, Rodriguez, A, Godoy, A, Rodriguez, V, Berrospi, P, Chavez, C, Negron, S, Heredia, J, Medina, F, Manrique, H, Cabrera, W, Cordova, F, Quinteros, T, Haro, J, Regalado, S, Guitton, J, Arbanil, H, Pansieri, M, Decoulx, E, Goube, P, de Labriolle, A, Labeque, J, Range, G, Cottin, Y, Montalescot, G, Cayla, G, Danchin, N, Angoulvant, D, Ferrario, E, Elbaz, M, Dubreuil, O, Fontaine, C, Sorbets, E, Omer, H, Al-Saif, S, Al-Faleh, H, Al-Shehri, A, El-Amin, O, Alshehri, H, Bazari, R, Hei, P, Ying, M, Chan, M, Wong, M, Ma, R, Siu, S, Tsang, C, Ferrario, M, Assanelli, E, Senni, M, Piatti, P, Calabro, P, Urbinati, S, Michisanti, M, Varbella, F, de Cosmo, S, Trevisan, R, Bellotti, S, Di Pasquale, G, Bongo, A, Uguccioni, M, Mannucci, E, Mauro, C, Ragonese, M, Fresco, C, Turturo, M, Marcucci, R, Lievano Triana, M, Arana, C, Accini, J, Botero, R, Muzyk-Osikowicz, M, Dada, F, Vallejo, G, Manzur, F, Isaza, D, Molina, D, Mesa, J, Quintero, A, Nyman, K, Makela, J, Strand, J, Nieminen, S, Taurio, J, Kuusela, M, Valle, T, Pietila, M, Kekki, S, Strandberg, T, Klutstein, M, Greenberg, G, Rozenman, Y, Chorin, E, Roguin, A, Lewis, B, Bashkin, A, Tan, E, Prado, J, Ferrolino, A, Babilonia, N, Barbas, B, Matiga, G, Coching, R, Drexel, H, Brath, H, Schnack, C, Hanusch, U, Fliesser-Gorzer, E, Paulweber, B, Ebenbichler, C, Prager, R, Huber, K, Wolzt, M, Auer, J, Berger, R, Schernthaner, G, Stanciulescu, G, Creteanu, M, Spiridon, M, Dobreanu, V, Vinereanu, D, Iosipescu, L, Istratoaie, O, Coman, I, Militaru, C, Cinteza, M, Nicolau, J, Kerr Saraiva, J, Widimsky, P, Kristensen, S, Hartikainen, J, Darius, H, Tse, H, Pais, P, Lev, E, de Luca, L, Ramos Lopez, G, Kontny, F, Zateyshchikov, D, Ruda, M, Elamin, O, Kovar, F, Bueno, H, Leonsson-Zachrisson, M, Bhatt D. 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D., O'Keefe D., Sabbah E., Bell A., Chouinard G., Wong B., Miller M., Gaudet D., Lachance P., Bata I., Petrella R., Gossard D., Dumas R., Ing D., Boyrazian H., Bessoudo R., Huynh T. T., Hart R., Belle-Isle J., Shukla D., Kelly A., Mazza G., Cha J., Henein S., Frechette A., Vizel S., Liutkus J. F., O'Mahony M., Halperin F., Kooy J., Graham J., Bailey A., Wojcik R., Wilderman I., Turi T., Motyovszki A., Merkely B., Kiss R. G., Kiraly C., Andrassy P., Sarszegi Z., Fulop T., Zilahi Z., Edes I., Papp A., Muller G., Czigany A., Zolyomi S., Koranyi L., Takacs J., Juhasz F., Benczur B., Kancz S., Foldi A., Nagy A. 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H., Strikwerda S., Bos R., de Melker E., Kuijper A., Louwerenburg H., Plomp J., Dantzig J. -M., Prins F., van Kesteren H., Willems F., Amoroso G., Carnero G., Duronto E., Besada D., Chacon C., Zangroniz P., Solis S., Liberman A., Sernia V., Alvarisqueta A., Maffei L., Vilamajo O. G., Garcia C., Sicer M., Muntaner J., Bordonava A., Albisu J., Zanini A., Rista L., Hominal M., Estrada J. N., Prado A., Gosparini D. M., Schiavi B., Castillo A. G., Ruiz J. G., Martinez G. R., Lopez V. G., Rosas E. L., Lopez G. R., Cantu E. G., de los Rios Ibarra M., Padilla F. P., Carrasco J. P., Carrillo L. V., Garcia J. D., Askar A. N., Salinas C. A., Gamba M. A., Sanchez C. G., Cantu A. G., Sanchez R. V., Madrigal J. C., Urbano R. H., Romo A. I., Gonzalez Juanatey J. R., Racugno P., Fillat A. C., de la Torre Hernandez J. M., Pelaez J. A., Cortada J. B., Pavia P. G., Navarro M. J., Asenjo R. M., Diaz F. F., Peligero E. B., Manterola F. A., Ortiz A. F., Mediavilla Garcia J. D., Ortuno F. M., Vera T. 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S., Sathe P., Adhyapak S., Nguyen T., Pham V., Do H., Nguyen A., Nguyen H., Truong B., Jamil-Copley S., Lang C., Pell A., Zaman A., Storey R., Swanson N., Sharman D., Braganza D., Hammond P., Moriarty A., Bain S., Pye M., Sharp A., Blagden M., Randeva H., Myhill T., Viswanathan G., Keeling P., Clifford P., Saxena M., Lyons K., McMurray J., Jaafar F., Murphy C., Cartwright S., Abouglila K., Antalik L., Krajci P., Urban M., Fazekas F., Pella D., Koleny D., Vykoukalova T., Macek V., Vinanska D., Jamriskova L., Such S., Fulop P., Farsky S., Bugan V., Strbova J., Micko K., Palka Jr J., Sivak V., Kristensen D., Refsgaard J., Holmvang L., Dixen U., Nielsen H., Egstrup K., Jensen L. 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C., Istratoaie O., Coman I., Militaru C., Cinteza M., Sinnaeve P. R., Nicolau J. C., Kerr Saraiva J. F., Widimsky P., Kristensen S. D., Hartikainen J., Darius H., Tse H. F., Pais P., Lev E., de Luca L., Ramos Lopez G. A., Kontny F., Babilonia N. A., Zateyshchikov D. A., Ruda M., Elamin O., Kovar F., Dalby A. J., Bueno H., Chiang C. -E., Parkhomenko A., Nguyen T. Q., and Leonsson-Zachrisson M.
- Abstract
Background: Patients with stable coronary artery disease and diabetes with previous percutaneous coronary intervention (PCI), particularly those with previous stenting, are at high risk of ischaemic events. These patients are generally treated with aspirin. In this trial, we aimed to investigate if these patients would benefit from treatment with aspirin plus ticagrelor. Methods: The Effect of Ticagrelor on Health Outcomes in diabEtes Mellitus patients Intervention Study (THEMIS) was a phase 3 randomised, double-blinded, placebo-controlled trial, done in 1315 sites in 42 countries. Patients were eligible if 50 years or older, with type 2 diabetes, receiving anti-hyperglycaemic drugs for at least 6 months, with stable coronary artery disease, and one of three other mutually non-exclusive criteria: a history of previous PCI or of coronary artery bypass grafting, or documentation of angiographic stenosis of 50% or more in at least one coronary artery. Eligible patients were randomly assigned (1:1) to either ticagrelor or placebo, by use of an interactive voice-response or web-response system. The THEMIS-PCI trial comprised a prespecified subgroup of patients with previous PCI. The primary efficacy outcome was a composite of cardiovascular death, myocardial infarction, or stroke (measured in the intention-to-treat population). Findings: Between Feb 17, 2014, and May 24, 2016, 11 154 patients (58% of the overall THEMIS trial) with a history of previous PCI were enrolled in the THEMIS-PCI trial. Median follow-up was 3·3 years (IQR 2·8–3·8). In the previous PCI group, fewer patients receiving ticagrelor had a primary efficacy outcome event than in the placebo group (404 [7·3%] of 5558 vs 480 [8·6%] of 5596; HR 0·85 [95% CI 0·74–0·97], p=0·013). The same effect was not observed in patients without PCI (p=0·76, pinteraction=0·16). The proportion of patients with cardiovascular death was similar in both treatment groups (174 [3·1%] with ticagrelor vs 183 (3·3%) with placebo
- Published
- 2019
13. Mucuna pruriens: A new strategy for Parkinsonʼs disease treatment in Africa. An update: 354
- Author
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Cassani, E., Barichella, M., Cilia, R., Akpalu, A., Ofosu-Budu, K., Cham, M., Ferrario, E., Faceli, E., Zecca, L., Sparvoli, F., Privitera, G., De Marco, P., Zecchinelli, A., Bonetti, A., Iorio, L., Amboni, M., Cereda, E., and Pezzoli, G.
- Published
- 2014
14. Uncertainty analysis of a model of an energy distribution system with solar panel generation by time-varying data analysis, Monte Carlo Simulation and Fuzzy Interval Analysis
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Ferrario, E, primary and Pini, A, additional
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- 2013
- Full Text
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15. Line sampling and Fuzzy Interval Analysis for the propagation
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Ferrario, E., primary, Pedroni, N., additional, and Zio, E., additional
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- 2013
- Full Text
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16. Monte Carlo and fuzzy interval propagation of hybrid uncertainties on a risk model
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Baraldi, P, primary, Pedroni, N, additional, Zio, E, additional, Ferrario, E, additional, Pasanisi, A, additional, and Couplet, M, additional
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- 2011
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17. Structure of Thermococcus litoralis Delta(1)-pyrroline-2-carboxylate reductase in complex with NADH and L-proline
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Ferraris, D.M., primary, Miggiano, R., additional, Ferrario, E., additional, and Rizzi, M., additional
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- 2020
- Full Text
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18. Capecitabine plus oxaliplatin and irinotecan regimen every other week: a phase I/II study in first-line treatment of metastatic colorectal cancer
- Author
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Bajetta, E., Celio, L., Ferrario, E., Di Bartolomeo, M., Denaro, A., Dotti, K., Mancin, M., Bajetta, R., Colombo, A., and Pusceddu, S.
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- 2007
19. Pathological features as predictors of recurrence after radical resection of gastric cancer
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Buzzoni, R., Bajetta, E., Di Bartolomeo, M., Miceli, R., Beretta, E., Ferrario, E., and Mariani, L.
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- 2006
20. Behavioral sensitization to different dopamine agonists in a parkinsonian rodent model of drug-induced dyskinesias
- Author
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Delfino, A M., Stefano, V A., Ferrario, E J., Taravini, E I.R., Murer, G M., and Gershanik, S O.
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- 2004
- Full Text
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21. Efficacy of a chemotherapy combination for the treatment of metastatic neuroendocrine tumours
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Bajetta, E., Ferrari, L., Procopio, G., Catena, L., Ferrario, E., Martinetti, A., Di Bartolomeo, M., Buzzoni, R., Celio, L., Vitali, M., Beretta, E., Seregni, E., and Bombardieri, E.
- Published
- 2002
22. Capecitabine in combination with two schedules of irinotecan (CPT-11) in advanced colorectal cancer: A pilot experience.
- Author
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Cassata, Antonino, Alù, M., Beretta, E., Ferrario, E., Lambiase, A., Comis, S., and Bajetta, E.
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- 2000
23. THE TREATMENT OF METASTATIC NEUROENDOCRINE TUMORS: ACTIVITY OF A COMBINATION CHEMOTHERAPY
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Procopio, G, Catena, L, Di Bartolomeo, M, Artale, S, Ferrari, L, Martinetti, A, Ferrario, E, Stani, S C, Alù, M, Buzzoni, R, Celio, L, and Bajetta, E
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- 2000
24. Representation and Modeling of the Chilean Electric Power Network for Seismic Resilience Analysis
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Ferrario, E., primary, Poulos, A., additional, la Llera, J. C. de, additional, Lorca, A., additional, Oneto, A., additional, and Magnere, C., additional
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- 2019
- Full Text
- View/download PDF
25. Luigi Preti (1881-1941) e la Clinica del Lavoro tra Devoto e Vigliani
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RIVA, MICHELE AUGUSTO, Deflorian, N, Ferrario, E, Mendola, M, Paticchia, V, Turato, M., Riva, M, Deflorian, N, Ferrario, E, Mendola, M, Paticchia, V, and Turato, M
- Subjects
History ,MED/02 - STORIA DELLA MEDICINA - Published
- 2016
26. Resilience Analysis Framework for Interconnected Critical Infrastructures
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Liu, X., primary, Ferrario, E., additional, and Zio, E., additional
- Published
- 2017
- Full Text
- View/download PDF
27. Luigi Preti (1881-1941) e la Clinica del Lavoro tra Devoto e Vigliani.
- Author
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Riva, M, Deflorian, N, Ferrario, E, Mendola, M, Paticchia, V, Turato, M, RIVA, MICHELE AUGUSTO, Turato, M., Riva, M, Deflorian, N, Ferrario, E, Mendola, M, Paticchia, V, Turato, M, RIVA, MICHELE AUGUSTO, and Turato, M.
- Published
- 2016
28. Centenariansin good health conditions
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Motta, M., Maugeri, D., Malaguarnera, M., Capurso, A., Colacicco, A. M., Solfrizzi, V., Bonafe', M., Barbi, C., Gaddi, A., D'Addato, S., Sangiorgi, Z., Trabucchi, M., Boffelli, S., Rozzini, R., Rapisarda, R., Tomasello, F. B., Bennati, E., Ferito, L., Frantone, A., Zoccolo, A., Perticone, F., Nardi, L., Berardelli, M., De Benedictis, G., Falcone, E., De Luca, M., Casotti, G., Monti, D., Petruzzi, E., Sorbi, S., Grassi, E., Latorraca, S., Bertolini, S., Agretti, M., Costelli, P., Nicita Mauro, V., Basile, G., Mari, D., Duca, F., Terrazzi, P., Bosi, E., Manzoni, M., Salvioli, G., Baldeli, M. V., Neri, M., Cossarizza, A., Troiano, L., Pini, G., Varricchio, M., Gambardella, A., Prolisso, G., Frada', G., Barbagallo, M., Pollina, R., Passeri, M., Sansoni, P., Lavagetto, G., Ferrari, E., Battegazzore, C., Molla, G., Senin, U., Cherubini, A., Polidori, M. C., Marigliano, V., Bauco, C., Borriello, C., Deiana, L., Carru, C., Pes, G. M., Baggio, G., Forconi, S., Boschi, S., Guerrini, M., Fabris, F., Cappa, G., and Ferrario, E.
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Aging ,Health (social science) ,Successful aging ,business.industry ,Centenarians ,Healthy centenarians ,Data science ,Text mining ,Medicine ,Geriatrics and Gerontology ,business ,Gerontology - Published
- 2002
29. Raltitrexed plus oxaliplatin in the treatment of metastatic colorectal cancer
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Cortinovis, D, Bajetta, E, Di Bartolomeo, M, Dognini, G, Beretta, E, Ferrario, E, Ricotta, R, Buzzoni, R, Cortinovis D, Bajetta E, Di Bartolomeo M, Dognini G, Beretta E, Ferrario E, Ricotta R, Buzzoni R., Cortinovis, D, Bajetta, E, Di Bartolomeo, M, Dognini, G, Beretta, E, Ferrario, E, Ricotta, R, Buzzoni, R, Cortinovis D, Bajetta E, Di Bartolomeo M, Dognini G, Beretta E, Ferrario E, Ricotta R, and Buzzoni R.
- Abstract
Aims and background: As raltitrexed and oxaliplatin (L-OHP) are both effective in the treatment of colorectal cancer but have different mechanisms of action, we studied the antitumoral activity and safety of their combined use in patients with advanced colorectal cancer. Methods: A 15-min intravenous infusion of raltitrexed (2.5 mg/m(2)) and a 180-min infusion of oxaliplatin (100 mg/m(2)) were administered on day 1 every three weeks for a maximum of six cycles. Results: The study involved 51 patients (27 males and 24 females) with a median age of 65 years (range, 43-78); 28 were aged >65 years. The primary tumor site was the colon in 35 patients and the rectum in 16. Thirty-four patients had received prior chemotherapy: 20 as adjuvant treatment and 14 as pre-treatment. The most frequent metastatic sites were liver (18 cases), lung (10 cases), liver + lung (8 cases) and lymph nodes (3 cases). Twenty-four patients completed the entire treatment plan. The most common toxicities were transaminitis (16 patients, grade 3-4), diarrhea (six patients, grade 3), nausea/vomiting (one patient, grade 4), and asthenia (one patient, grade 3). The treatment was stopped in one patient because of prolonged grade 4 transaminitis. The adverse event profile was similar in the patients aged >65 years and <65 years. Complete responses were observed in 2 patients, partial responses in 12, stable disease in 23, and progression in 8. Conclusions: The results of the study suggest that the raltitrexed plus oxaliplatin regimen is feasible and clinically active in advanced colorectal cancer.
- Published
- 2005
30. Role of ambulatory blood pressure monitoring in long-term follow-up of gestational hypertension
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Gessi, V., Maresca, ANDREA MARIA, Mongiardi, Christian, Merletti, F., Annoni, F., Vacirca, V., Gadaleta, C., Robustelli Test, L., Ferrari, V., Ferrario, E., Messina, P., and Grandi, ANNA MARIA
- Published
- 2014
31. Vitalità culturale in contesti di declino demografico? Il caso del Comelico
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Ferrario, E. and Ferrario, Viviana
- Subjects
Sviluppo locale ,vitalità culturale ,Alpi - Published
- 2014
32. Randomized multicenter Phase II trial of two different schedules of irinotecan combined with capecitabine as first-line treatment in metastatic colorectal carcinoma
- Author
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Bajetta, E, Di Bartolomeo, M, Mariani, L, Cassata, A, Artale, S, Frustaci, S, Pinotti, G, Bonetti, A, Carreca, I, Biasco, G, Bonaglia, L, Marini, G, Iannelli, A, Cortinovis, D, Ferrario, E, Beretta, E, Lambiase, A, Buzzoni, R, Bajetta E, Di Bartolomeo M, Mariani L, Cassata A, Artale S, Frustaci S, Pinotti G, Bonetti A, Carreca I, Biasco G, Bonaglia L, Marini G, Iannelli A, Cortinovis D, Ferrario E, Beretta E, Lambiase A, Buzzoni R, Bajetta, E, Di Bartolomeo, M, Mariani, L, Cassata, A, Artale, S, Frustaci, S, Pinotti, G, Bonetti, A, Carreca, I, Biasco, G, Bonaglia, L, Marini, G, Iannelli, A, Cortinovis, D, Ferrario, E, Beretta, E, Lambiase, A, Buzzoni, R, Bajetta E, Di Bartolomeo M, Mariani L, Cassata A, Artale S, Frustaci S, Pinotti G, Bonetti A, Carreca I, Biasco G, Bonaglia L, Marini G, Iannelli A, Cortinovis D, Ferrario E, Beretta E, Lambiase A, and Buzzoni R
- Abstract
BACKGROUND. The aim of the current randomized Phase II study was to investigate the efficacy and safety of capecitabine combined with irinotecan as first-line treatment in metastatic colorectal carcinoma (CRC). METHODS. A total of 140 patients received capecitabine at a dose of 1250 mg/m2 twice daily on Days 2-15 and irinotecan at a dose of either 300 mg/m2 on Day 1 (Arm A) or 150 mg/m2 on Days 1 and 8 (Arm B) every 3 weeks. During the course of the study, enrollment was continued using lower doses of capecitabine (1000 mg/m2 twice daily) and irinotecan (Arm A: 240 mg/m2; Arm B: 120 mg/m2) to improve the safety profile of the combinations. RESULTS. Efficacy was evaluable in 134 patients (68 in Arm A, 66 in Arm B). Objective responses were observed in 46% of the patients (8% complete response [CR]), including 47% in Arm A (9% CR; 38% partial response [PR]) and 44% in Arm B (8% CR; 36% PR). The median progression-free survival was 8.3 months in Arm A and 7.6 months in Arm B. Among the first 52 patients treated with the higher doses, the most frequent Grade 3-4 adverse event was diarrhea (27%). The lower doses adopted in the subsequent 88 patients led to better diarrhea control, particularly in Arm A, and significant reductions in the incidence of all-grade hand-foot syndrome and abdominal pain. CONCLUSIONS. The capecitabine and irinotecan combination was a highly active first-line therapy in metastatic CRC. An acceptable safety profile was observed after dose reduction, particularly when irinotecan was administered on 1 day.
- Published
- 2004
33. Efficacy of treatment with irinotecan and oxaliplatin combination in FU-resistant metastatic colorectal cancer patients
- Author
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Bajetta, E, Beretta, E, Di Bartolomeo, M, Cortinovis, D, Ferrario, E, Dognini, G, Toffolatti, L, Buzzoni, R, Bajetta E, Beretta E, Di Bartolomeo M, Cortinovis D, Ferrario E, Dognini G, Toffolatti L, Buzzoni R, Bajetta, E, Beretta, E, Di Bartolomeo, M, Cortinovis, D, Ferrario, E, Dognini, G, Toffolatti, L, Buzzoni, R, Bajetta E, Beretta E, Di Bartolomeo M, Cortinovis D, Ferrario E, Dognini G, Toffolatti L, and Buzzoni R
- Abstract
Objectives: As single agents, irinotecan and oxaliplatin are active in colorectal cancer after fluorouracil (FU)-containing regimen failure. Their synergistic activity and non-overlapping toxicity profile are well documented, but more data are needed to explore their exact sequence. The aim of this study was to evaluate the activity and tolerability of irinotecan followed by oxaliplatin in patients with FU-resistant colorectal cancer. Methods: FU resistance was defined as disease progression during or within 6 months of discontinuing first-line or adjuvant FU/leucovorin chemotherapy. The study treatment consisted of irinotecan 150 mg/m2 on days 1 and 8 followed by oxaliplatin 85 mg/m2 on day 1 every 3 weeks. In order to improve the safety profile, we changed the schedule during the study to irinotecan 300 mg/m2 on day 1 and oxaliplatin 85 mg/m2on day 2 every 3 weeks. Results: Of 54 patients treated, the 45 patients with measurable disease were assessed in the efficacy analysis, whereas all patients receiving at least one cycle were evaluated in the safety analysis. Of the patients assessed for efficacy analysis, 19 cases received the first schedule and 26 patients received the second schedule. Twenty-two patients (49%) responded, 10 of the first schedule and 12 of the second schedule group. Stable disease was observed in 35% of all patients. The median response duration was 6.5 months (range 3-10), the median time to progression was 8 months (range 6-10), and the overall survival was 15 months (10-26+). The NCI-CTC grade 3 side effects documented in all of the treated patients were: nausea/vomiting (11%), diarrhea (18%), and neutropenia (7%); grade 4 diarrhea was observed in 2% of patients. Conclusion: The combination of irinotecan followed by oxaliplatin combination is well tolerated and highly active in FU-resistant metastatic colorectal cancer patients.
- Published
- 2004
34. Treatment of cancer-related anemia with epoetin alfa: A review
- Author
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Ferrario, E, Ferrari, L, Bidoli, P, De Candis, D, Del Vecchio, M, De Dosso, S, Buzzoni, R, Bajetta, E, Ferrario E, Ferrari L, Bidoli P, De Candis D, Del Vecchio M, De Dosso S, Buzzoni R, Bajetta E., Ferrario, E, Ferrari, L, Bidoli, P, De Candis, D, Del Vecchio, M, De Dosso, S, Buzzoni, R, Bajetta, E, Ferrario E, Ferrari L, Bidoli P, De Candis D, Del Vecchio M, De Dosso S, Buzzoni R, and Bajetta E.
- Abstract
Erythropoietin (EPO) is a hematopoietic growth hormone that regulates survival, proliferation, and differentiation of erythroid progenitor cells. A reduction in tissue oxygenation stimulates EPO production, through a complex feedback mechanism. Patients with cancer-related anemia have an inadequate EPO response that is further impaired by cancer treatments such as chemotherapy. Cancer-related anemia substantially impairs patient functioning and may contribute to poor treatment outcomes. A significant number of studies demonstrates that treatment of anemia in cancer patients using recombinant human EPO (rHuEPO, epoetin alfa) significantly increases haemoglobin (Hb) levels, reduces transfusion requirements, and improves quality of life, particularly by relieving fatigue. Recent data also show that epoetin alfa therapy may improve cognitive function in patients receiving chemotherapy. In addition, the correction of anemia may prolong survival by enhancing tumor oxygenation, thus increasing tumor sensitivity to chemotherapy or radiation. The indicated dose of epoetin alfa is 150-300 IU/kg three times per week, but it is commonly dosed at 40,000-60,000 IU once weekly based on trial data and extensive clinical use. Determining the timing of initiation of epoetin alfa is a clinical judgement; however, data suggest that patient functioning declines and the risk of transfusion increases when the Hb level falls under 12 g/dL
- Published
- 2004
35. Assessment of sense of taste in Italian centenarians
- Author
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Baggio, G., Dalla Vestra, M., Donazzan, S., Barbagallo Sangiorgi, G., Barbagallo, M., Frada, G., Bertolini, S., Agretti, M., Costelli, P., Bosi, E., Manzoni, M., Tomasello, F. B., Capurso, A., Colacicco, A. M., Solfrizzi, V., Fabris, F., Cappa, G., Ferrario, E., Forconi, S., Guerrini, M., Boschi, S., Franceschi, C., Cossarizza, A., Monti, D., Gaddi, A., D'Addato, S., Galletti, C., Giarelli, L., Cavalieri, F., Stanta, G., Mari, D., Duca, F., Ferrazzi, P., Marigliano, V., Bauco, C., Cacciafesta, M., Masotti, G., Marchionni, N., Petruzzi, E., Mattace, R., Motta, M., Pansini, L., Motta, L., Rapisarda, R., Receputo, G., Passeri, M., Fagnoni, F., Sansoni, P., Salvioli, G., Baldelli, M. V., Neri, M., Senin, U., Cherubini, A., Polidori, M. C., Trabucchi, M., Boffelli, S., Rozzini, R., Varricchio, M., Gambardella, A., and Paolisso, G.
- Subjects
Aging ,medicine.medical_specialty ,Study groups ,Taste ,Health (social science) ,Mini–Mental State Examination ,medicine.diagnostic_test ,business.industry ,Sense of taste ,Mean age ,Audiology ,Control subjects ,Centenarians ,Elderly ,medicine ,Wine tasting ,Geriatrics and Gerontology ,business ,Gerontology - Abstract
The Italian multicentric study on centenarians (IMSC) was aimed at assessing the level of preservation of the sense of taste, and at estimating to what extent the recognition of various gustative stimuli can give satisfaction and information regarding the surrounding environment for the centenarians. Taste sensitivity has been qualitatively established in a group of 126 Italian centenarians (mean age 101.9+/-1.4 years) and compared to that of a group of 100 elderly subjects (mean age 70.5+/-5.0 years). All the individuals included in the study groups had a mini mental state examination (MMSE) score larger than 19. The results revealed that taste sensitivity is significantly reduced in the centenarians; as a matter of fact, the elderly control subjects are able to perceive taste stimuli in 84.25+/-3.40% of the testing, while the centenarians were successful only in 74.23+/-6.19% of the experiments (P
- Published
- 1998
36. Randomized Multicenter Phase II Trial of Two Different Schedules of Irinotecan Combined with Capecitabine as First-Line Treatment in Metastatic Colorectal Carcinoma
- Author
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BAJETTA E, DI BARTOLOMEO M, MARIANI L, CASSATA A, ARTALE S, FRUSTACI S, PINOTTI G, BONETTI A, CARRECA I, BONAGLIA L, MARINI G, IANNELLI A, CORTINOVIS D, FERRARIO E, BERETTA E, LAMBIASE A, BUZZONI R, ITALIAN TRIALS IN MEDICAL ONCOLOGY I. T. M. O. GROUP, BIASCO, GUIDO, EMILIO BAJETTA, MARIA DI BARTOLOMEO, LUIGI MARIANI, ANTONIO CASSATA, SALVATORE ARTALE, SERGIO FRUSTACI, GRAZIELLA PINOTTI, ANDREA BONETTI, CARRECA I, GUIDO BIASCO, LUIGI BONAGLIA, GIOVANNI MARINI, ANTONIO IANNELLI, DIEGO CORTINOVIS, ERMINA FERRARIO, ELENA BERETTA, ANTONIO LAMBIASE, ROBERTO BUZZONI, BAJETTA E, DI BARTOLOMEO M, MARIANI L, CASSATA A, ARTALE S, FRUSTACI S, PINOTTI G, BONETTI A, BIASCO G., BONAGLIA L, MARINI G, IANNELLI A, CORTINOVIS D, FERRARIO E, BERETTA E, LAMBIASE A, BUZZONI R, and ITALIAN TRIALS IN MEDICAL ONCOLOGY I.T.M.O. GROUP.
- Subjects
Adult ,Male ,Cancer Research ,medicine.medical_specialty ,Colorectal cancer ,Phases of clinical research ,COLON CANCER ,Irinotecan ,Gastroenterology ,Deoxycytidine ,Drug Administration Schedule ,colorectal carcinoma, first-line treatment, irinotecan and capecitabine combination, Phase II trial ,law.invention ,Capecitabine ,Randomized controlled trial ,law ,Internal medicine ,Antineoplastic Combined Chemotherapy Protocols ,medicine ,Humans ,Neoplasm Metastasis ,Adverse effect ,Aged ,XELIRI ,business.industry ,Carcinoma ,Cancer ,Middle Aged ,medicine.disease ,Surgery ,Oncology ,Drug Evaluation ,Camptothecin ,Female ,Fluorouracil ,business ,Colorectal Neoplasms ,medicine.drug - Abstract
BACKGROUND The aim of the current randomized Phase II study was to investigate the efficacy and safety of capecitabine combined with irinotecan as first-line treatment in metastatic colorectal carcinoma (CRC). METHODS A total of 140 patients received capecitabine at a dose of 1250 mg/m2 twice daily on Days 2–15 and irinotecan at a dose of either 300 mg/m2 on Day 1 (Arm A) or 150 mg/m2 on Days 1 and 8 (Arm B) every 3 weeks. During the course of the study, enrollment was continued using lower doses of capecitabine (1000 mg/m2 twice daily) and irinotecan (Arm A: 240 mg/m2; Arm B: 120 mg/m2) to improve the safety profile of the combinations. RESULTS Efficacy was evaluable in 134 patients (68 in Arm A, 66 in Arm B). Objective responses were observed in 46% of the patients (8% complete response [CR]), including 47% in Arm A (9% CR; 38% partial response [PR]) and 44% in Arm B (8% CR; 36% PR). The median progression-free survival was 8.3 months in Arm A and 7.6 months in Arm B. Among the first 52 patients treated with the higher doses, the most frequent Grade 3–4 adverse event was diarrhea (27%). The lower doses adopted in the subsequent 88 patients led to better diarrhea control, particularly in Arm A, and significant reductions in the incidence of all-grade hand-foot syndrome and abdominal pain. CONCLUSIONS The capecitabine and irinotecan combination was a highly active first-line therapy in metastatic CRC. An acceptable safety profile was observed after dose reduction, particularly when irinotecan was administered on 1 day. Cancer 2004;100:279–87. © 2003 American Cancer Society.
- Published
- 2004
37. long term follow up of hypertensive disorders of pregnancy: case control study with ambulatory blood pressure monitoring
- Author
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Gessi, V, Maresca, ANDREA MARIA, Mongiardi, Christian, Lippi, A, Molaro, M, Ferrario, E, Cromi, Antonella, Ghezzi, F, Serratì, M, Bertolini, A, and Grandi, ANNA MARIA
- Published
- 2013
38. Follow up a lungo termine di ipertensione gestazionale: studio caso-controllo con monitoraggio ambulatorio della pressione arteriosa
- Author
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Gessi, V, Maresca, ANDREA MARIA, Mongiardi, Christian, Lippi, A, Molaro, M, Ferrario, E, Cromi, Antonella, Ghezzi, F, Serratì, M, Bertolini, A, and Grandi, ANNA MARIA
- Published
- 2013
39. Analysis of the Robustness and Recovery of Critical Infrastructures by Goal Tree–Success Tree: Dynamic Master Logic Diagram, Within a Multistate System-of-Systems Framework, in the Presence of Epistemic Uncertainty
- Author
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Ferrario, E., primary, Pedroni, N., additional, and Zio, E., additional
- Published
- 2015
- Full Text
- View/download PDF
40. Circle time for social and emotional learning in primary school
- Author
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Cefai, C, Ferrario, E, Cavioni, V, Carter, A, Grech, T, Grech, T., Cefai, C, Ferrario, E, Cavioni, V, Carter, A, Grech, T, and Grech, T.
- Abstract
This paper discusses the findings and implications of a semi-randomised control trial study on the effectiveness of circle time (CT) on primary school students' social and emotional learning, as well as classroom teachers' and students' experience of CT. A social and emotional learning programme was delivered through CT by trained classroom teachers across the years in one primary school, with other classrooms serving as control groups. The classroom teachers completed the Strengths and Difficulties Questionnaire (SDQ) at pre- and post-intervention, while the CT teachers also completed a questionnaire on their experience of implementing CT in the classroom. The CT students also completed a questionnaire on their own experience of CT. The SDQ scores suggest that CT students showed less internalised difficulties when compared to their control peers, while the qualitative data from both teachers and students suggest that the CT students also exhibited less behaviour problems and more prosocial behaviour. The study identifies various strengths and weaknesses of the programme and makes recommendations on how it could be organised more effectively in the classroom. The paper concludes that rather than taking CT as the default option for nurturing such values as student empowerment, inclusion and equity, there is a need for further rigorous studies on the impact of CT not only on students' social and emotional learning and behaviour but also on the classroom relationships and climate.
- Published
- 2014
41. Uncertainty analysis of a model of an energy distribution system with solar panel generation by time-varying data analysis, Monte carlo simulation and fuzzy interval analysis
- Author
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Ferrario, E., Pini, Alessia, Pini, A. (ORCID:0000-0001-9235-3062), Ferrario, E., Pini, Alessia, and Pini, A. (ORCID:0000-0001-9235-3062)
- Abstract
The uncertainties in the model of an energy distribution system made of a solar panel, a storage energy system and loads (power demanded by the end-users) are investigated, treating the epistemic variables as possibilistic and the aleatory ones as probabilistic. In particular, time-varying probabilistic distributions of the solar irradiation and the power demanded by the end-users is inferred from historical data. Then a computational framework for the joint propagation of both types of uncertainty is applied through the model of the energy distribution system to compute the Expected Energy Not Supplied. © 2014 Taylor & Francis Group, London.
- Published
- 2014
42. Clinical epidemiology of IgE-mediated cutaneous and oculo-conjunctival allergic diseases
- Author
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Renzi, G., Nicolotti, N., Filippi, M., Lovato, L., Feyles, G., Ferrario, E., Siclari, N., Mazzarello, M. G., Torriglia, A. M., Perfumo, M., Cremonte, L. G., Capizzi, S., and Giuseppe La Torre
- Subjects
specific IgEs ,lcsh:Public aspects of medicine ,Allergic oculo-conjunctivitis ,allergic dermatitis ,lcsh:R ,DOAJ:Public Health ,lcsh:Medicine ,lcsh:RA1-1270 ,DOAJ:Health Sciences - Abstract
Background: IgE-mediated allergic disease may clinically manifest itself with either a single symptom or a multisymptomatic disease involving different organs. In this work we investigated whether gender and age of the patients and reactivity to specific allergens are related to different clinical presentations of IgE-mediated allergic disease, considering in particular eye-conjunctival and cutaneous symptoms, alone or in combination.Methods: Epidemiological and clinical data related to patients of the Local Health Unit of Torino and Alessandria were collected. Measuring of specific Immunoglobulin E (IgE) was carried out by using allergenic extracts and by the employment of the chemiluminescence method. Clinical outcomes were the presence of eye-conjunctival, cutaneous (with also other symptom), and only cutaneous symptoms. The covariates under study were the type of allergen (mite, epithelium, poaceae, food, trees and grasses), number and localisation of the allergic reactions, gender, age over 30 years. For each clinical outcome, a logistic regression analysis was performed. Statistical significance was set at p < 0.05.Results: 844 patients with allergic problems (clinical manifestations of allergic disease) entered the study. We found that exposure to epithelium [OR=3,61; IC 95% (2,17; 6,00)], poaceae [OR=2,24; IC 95% (1,46; 3,42)], grasses [OR=2,06; IC 95% (1.35; 3,14)] and age over 30 years [OR=2,05; IC 95% (1,35; 3,13)] are risk factors for the development of eye-conjunctival symptoms. With regard to cutaneous allergic reactions, exposure to mite [OR=1,49; IC 95% (1,07; 2,08)], food [OR=4,16; IC 95% (3,01; 5,75)] and multidistrict symptoms [OR=3,63; IC 95% (2,54; 5,20)] should be risk factors. Instead, considering only cutaneous reactions, possible risk factor is the exposure to food [OR=3,58; IC 95% (2,54; 5,03)]. The exposure to trees is associated with a reduction of the likelihood to have cutaneous [OR=0,45; IC 95% (0,26; 0,76)] and only cutaneous reactions [OR=0,24; IC 95% (0,11; 0,53)]. For only cutaneous symptoms, a reduction in probability is present for the exposure to the grasses [OR=0,60; IC 95% (0,38; 0,94)] too.Conclusions: The study highlighted significant associations between subgroups of allergens and specific symptoms. As a consequence, in the presence of cutaneous symptoms, IgE tests could be restricted to mite and food, and to epithelium, poaceae and grasses in the presence of oculo-conjunctival symptoms.
- Published
- 2008
43. Analysis of the Robustness of Critical Infrastructures Within a Multistate Systems-of-Systems Framework in the Presence of Epistemic Uncertainties
- Author
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Ferrario, E., primary, Pedroni, N., additional, and Zio, E., additional
- Published
- 2014
- Full Text
- View/download PDF
44. Salute mentale e dinamiche relazionali nei gruppi professionali. Il 'conosciuto non pensato' nei contesti educativi e formativi e il ruolo del 'gruppo resiliente'
- Author
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PALMIERI, CRISTINA, Ferrario, E, RIVA, MARIA GRAZIA, FERRARIO, ERIKA, PALMIERI, CRISTINA, Ferrario, E, RIVA, MARIA GRAZIA, and FERRARIO, ERIKA
- Abstract
Mental health in the educative workplace is the theme of this research. It is pregnant because the mental health was a fundamental right declared at the European conference of Bruxelles, organized by World Health Organization last June. The promotion and the support of the well-being in workplace was one of the most important focus to assure a good quality of life. However, often just in the contests of the help-professions, where mental health should be promoted, the staff lives distressing experiences in the relationships with users, peers and institution, without a place for nominate, think and elaborate the discomfort in relation at the device where it shows itself. The emotions and the representations become a “knew didn’t think” that remains like a shadow, a loop that only if released can transform itself in a precious resource for “learn to experience”. This is the point of my qualitative intervention on the field based on the model of the “clinic of the formation”: reflecting how the group works has re-launch a formative project that’s useful for think back to the roles, the emotions, the organization and the planning of the activities; it makes the group “resilient”, that is capable to cope the difficulty and the stress that every day the educative work causes at the educators.
- Published
- 2010
45. Hierarchical propagation of probabilistic and non-probabilistic uncertainty in the parameters of a risk model
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Pedroni, N., primary, Zio, E., additional, Ferrario, E., additional, Pasanisi, A., additional, and Couplet, M., additional
- Published
- 2013
- Full Text
- View/download PDF
46. Determinants of depression in 111 italian patients with systemic sclerosis
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Beretta, L., primary, Astori, S., additional, Ferrario, E., additional, Caronni, M., additional, Raimondi, M., additional, and Scorza, R., additional
- Published
- 2011
- Full Text
- View/download PDF
47. 6510 Sequential therapy with FOLFIRI followed by docetaxel plus cisplatin: a promising adjuvant chemotherapy in gastric adenocarcinoma. 5-year follow-up results of the I.T.M.O. Group study
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Bartolomeo, M. Di, primary, Buzzoni, R., additional, Lo Vullo, S., additional, Ferrario, E., additional, Manzoni, M., additional, Gevorgyan, A., additional, Bochicchio, A.M., additional, Cordio, S., additional, Ardizzoni, A., additional, and Bajetta, E., additional
- Published
- 2009
- Full Text
- View/download PDF
48. Rediscovering immunotherapy in combination with molecularly targeted agents in renal cell cancer
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Procopio, G., primary, Pietrantonio, F., additional, Verzoni, E., additional, Guadalupi, V., additional, Ducceschi, M., additional, and Ferrario, E., additional
- Published
- 2008
- Full Text
- View/download PDF
49. Reduced natural killer cell activity and IL-2 production in malnourished cancer patients
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L. Cozzaglio, Ferrario E, Maria Luisa Villa, Bergamasco E, F. Bozzetti, and E. Clerici
- Subjects
Interleukin 2 ,Adult ,Cytotoxicity, Immunologic ,Male ,Cancer Research ,medicine.medical_specialty ,Interferon alpha-2 ,Peripheral blood mononuclear cell ,Natural killer cell ,Cell Line ,Immune system ,Reference Values ,Internal medicine ,Immunopathology ,Neoplasms ,medicine ,Humans ,Phytohaemagglutinin ,Aged ,biology ,Cancer ,Interferon-alpha ,Middle Aged ,medicine.disease ,Reduced natural killer cell activity ,Recombinant Proteins ,Nutrition Disorders ,Killer Cells, Natural ,Endocrinology ,medicine.anatomical_structure ,Oncology ,Immunology ,biology.protein ,Interleukin-2 ,Female ,medicine.drug ,Research Article - Abstract
Natural killer (NK) cell activity was measured in the peripheral blood mononuclear cells (PBMC) from malnourished (MN) and well-nourished (WN) cancer patients and in healthy controls. A marked depression of NK activity was observed in MN cancer patients with moderate protein-calorie malnutrition (PCM), but not in WN cancer patients nor in the healthy controls. The depression of NK activity did not correlate with the localisation of the tumour, patient's age or body weight reduction. The defective NK activity of PBMC from MN cancer patients was restored to normal by rIL-2, but not by alfa-rIFN. Parenteral nutrition of MN patients with the proper amount of proteins and calories quickly corrected the depressed NK activity, indicating a central role of malnutrition in the genesis of their immune disfunction. PBMC from MN cancer patients produced lower amounts of IL-2, as compared with healthy controls, when stimulated in vitro; the most frequently affected were the responses to recall antigens such as influenza virus vaccine (FLU), while those to allogeneic PBMC (ALLO) and phytohaemagglutinin (PHA) were less affected. However, for each patient the ability to produce IL-2 in vitro did not correlate with NK activity, thus showing how the impairment of NK activity is not subsequent to a decreased production of endogenous IL-2. In summary, it can be concluded that malnutrition, rather than malignancy, plays a major role in the immune dysfunction of cancer patients.
- Published
- 1991
50. A dose finding study with erlotinib in combination to irinotecan and capecitabine in metastatic colorectal cancer (mCRC) patients
- Author
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Di Bartolomeo, M., primary, Bajetta, E., additional, Buzzoni, R., additional, Ferrario, E., additional, Mariani, L., additional, Gevorgyan, A., additional, Dotti, K., additional, Longarini, R., additional, Platania, M., additional, and Canova, S., additional
- Published
- 2006
- Full Text
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