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1,405 results on '"Ferrarese, P."'

1. A Virgo Environmental Survey Tracing Ionised Gas Emission (VESTIGE): XVI. The ubiquity of truncated star-forming disks across the Virgo cluster environment

Author

Morgan, C. R., Balogh, M. L., Boselli, A., Fossati, M., Lawlor-Forsyth, C., Sazonova, E., Amram, P., Boquien, M., Braine, J., Cortese, L., Côté, P., Cuillandre, J. C., Ferrarese, L., Gwyn, S., Hensler, G., Junais, and Roediger, J.

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

We examine the prevalence of truncated star-forming disks in the Virgo cluster down to $M_* \simeq 10^7 ~\text{M}_{\odot}$. This work makes use of deep, high-resolution imaging in the H$\alpha$+[NII] narrow-band from the Virgo Environmental Survey Tracing Ionised Gas Emission (VESTIGE) and optical imaging from the Next Generation Virgo Survey (NGVS). To aid in understanding the effects of the cluster environment on star formation in Virgo galaxies, we take a physically-motivated approach to define the edge of the star-forming disk via a drop-off in the radial specific star formation rate profile. Comparing with the expected sizes of normal galactic disks provides a measure of how truncated star-forming disks are in the cluster. We find that truncated star-forming disks are nearly ubiquitous across all regions of the Virgo cluster, including beyond the virial radius (0.974 Mpc). The majority of truncated disks at large clustercentric radii are of galaxies likely on first infall. As the intra-cluster medium density is low in this region, it is difficult to explain this population with solely ram-pressure stripping. A plausible explanation is that these galaxies are undergoing starvation of their gas supply before ram-pressure stripping becomes the dominant quenching mechanism. A simple model of starvation shows that this mechanism can produce moderate disk truncations within 1-2 Gyr. This model is consistent with `slow-then-rapid' or `delayed-then-rapid' quenching, where the early starvation mode drives disk truncations without significant change to the integrated star formation rate, and the later ram-pressure stripping mode rapidly quenches the galaxy. The origin of starvation may be in the group structures that exist around the main Virgo cluster, which indicates the importance of understanding pre-processing of galaxies beyond the cluster virial radius., Comment: 22 pages, 12 figures, accepted in Astronomy&Astrophysics

Published
2024

2. The EUSO-SPB2 Fluorescence Telescope for the Detection of Ultra-High Energy Cosmic Rays

Author

Adams Jr., James H., Allard, Denis, Alldredge, Phillip, Anchordoqui, Luis, Anzalone, Anna, Battisti, Matteo, Belov, Alexander A., Bertaina, Mario, Bertone, Peter F., Blin-Bondil, Sylvie, Burton, Julia, Cafagna, Francesco S., Casolino, Marco, Černý, Karel, Christ, Mark J., Colalillo, Roberta, Crawford, Hank J., Creusot, Alexandre, Cummings, Austin, Diesing, Rebecca, Di Nola, Alessandro, Ebisuzaki, Toshikazu, Eser, Johannes, Ferrarese, Silvia, Filippatos, George, Finch, William W., Flaminio, Flavia, Fornaro, Claudio, Fuehne, Duncan, Fuglesang, Christer, Garg, Diksha, Golzio, Alessio, Guarino, Fausto, Guépin, Claire, Heibges, Tobias, Judd, Eleanor G., Klimov, Pavel A., Krizmanic, John F., Kungel, Viktoria, Kupari, Luke, Kuznetsov, Evgeny, Manfrin, Massimiliano, Marszal, Wlodzimierz, Matthews, John N., Mese, Marco, Meyer, Stephan S., Mignone, Marco, Miyamoto, Hiroko, Murashov, Alexey S., Nachtman, Jane M., Olinto, Angela V., Onel, Yasar, Osteria, Giuseppe, Panico, Beatrice, Parizot, Ètienne, Paul, Tom, Pech, Miroslav, Perfetto, Francesco, Piotrowski, Lech W., Plebaniak, Zbigniew, Posligua, Jonatan, Prévôt, Guillaume, Przybylak, Marika, Reardon, Patrick, Reno, Mary Hall, Ricci, Marco, Sarazin, Fred, Schovánek, P., Scotti, Valentina, Shinozaki, Kenji, Soriano, Jorge F., Stillwell, Ben K., Szabelski, Jacek, Takizawa, Yoshiyuki, Trofimov, Daniil, Unel, Fredrik, Valore, Laura, Venters, Tonia M., Watts Jr., John, Wiencke, Lawrence, Wistrand, Hannah, and Young, Roy

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena
Abstract

The Extreme Universe Space Observatory on a Super Pressure Balloon 2 (EUSO-SPB2) flew on May 13$^{\text{th}}$ and 14$^{\text{th}}$ of 2023. Consisting of two novel optical telescopes, the payload utilized next-generation instrumentation for the observations of extensive air showers from near space. One instrument, the fluorescence telescope (FT) searched for Ultra-High Energy Cosmic Rays (UHECRs) by recording the atmosphere below the balloon in the near-UV with a 1~$\mu$s time resolution using 108 multi-anode photomultiplier tubes with a total of 6,912 channels. Validated by pre-flight measurements during a field campaign, the energy threshold was estimated around 2~EeV with an expected event rate of approximately 1 event per 10 hours of observation. Based on the limited time afloat, the expected number of UHECR observations throughout the flight is between 0 and 2. Consistent with this expectation, no UHECR candidate events have been found. The majority of events appear to be detector artifacts that were not rejected properly due to a shortened commissioning phase. Despite the earlier-than-expected termination of the flight, data were recorded which provide insights into the detectors stability in the near-space environment as well as the diffuse ultraviolet emissivity of the atmosphere, both of which are impactful to future experiments.

Published
2024
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3. Instantaneous control strategies for magnetically confined fusion plasma

Author

Albi, Giacomo, Dimarco, Giacomo, Ferrarese, Federica, and Pareschi, Lorenzo

Subjects
Mathematics - Numerical Analysis
Abstract

The principle behind magnetic fusion is to confine high temperature plasma inside a device in such a way that the nuclei of deuterium and tritium joining together can release energy. The high temperatures generated needs the plasma to be isolated from the wall of the device to avoid damages and the scope of external magnetic fields is to achieve this goal. In this paper, to face this challenge from a numerical perspective, we propose an instantaneous control mathematical approach to steer a plasma into a given spatial region. From the modeling point of view, we focus on the Vlasov equation in a bounded domain with self induced electric field and an external strong magnetic field. The main feature of the control strategy employed is that it provides a feedback on the equation of motion based on an instantaneous prediction of the discretized system. This permits to directly embed the minimization of a given cost functional into the particle interactions of the corresponding Vlasov model. The numerical results demonstrate the validity of our control approach and the capability of an external magnetic field, even if in a simplified setting, to lead the plasma far from the boundaries.

Published
2024

4. The Next Generation Virgo Cluster Survey (NGVS). XXVII.The Size and Structure of Globular Cluster Systems and their Connection to Dark Matter Halos

Author

Lim, Sungsoon, Peng, Eric W., Côté, Patrick, Ferrarese, Laura, Roediger, Joel C., Liu, Chengze, Spengler, Chelsea, Sola, Elisabeth, Duc, Pierre-Alain, Sales, Laura V., Blakeslee, John P., Cuillandre, Jean-Charles, Durrell, Patrick R., Emsellem, Eric, Gwyn, Stephen D. J., Lançon, Ariane, Marleau, Francine R., Mihos, J. Christopher, Müller, Oliver, Puzia, Thomas H., and Sánchez-Janssen, Rubén

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

We study the size and structure of globular clusters (GC) systems of 118 early-type galaxies from the NGVS, MATLAS, and ACSVCS surveys. Fitting S\'ersic profiles, we investigate the relationship between effective radii of GC systems ($R_{e, \rm gc}$) and galaxy properties. GC systems are 2--4 times more extended than host galaxies across the entire stellar mass range of our sample ($10^{8.3} < M_* < 10^{11.6}~M_{\odot}$). The relationship between $R_{e, \rm gc}$ and galaxy stellar mass exhibits a characteristic "knee" at a stellar mass of $M_p \simeq 10^{10.8}$, similar to galaxy $R_e$--stellar mass relationship. We present a new characterization of the traditional blue and red GC color sub-populations, describing them with respect to host galaxy $(g'-i')$ color ($\Delta_{gi}$): GCs with similar colors to their hosts have a "red" $\Delta_{gi}$, and those significantly bluer GCs have a "blue" $\Delta_{gi}$. The GC populations with red $\Delta_{gi}$, even in dwarf galaxies, are twice as extended as the stars, suggesting that formation or survival mechanisms favor the outer regions. We find a tight correlation between $R_{e, \rm gc}$ and the total number of GCs, with intrinsic scatter $\lesssim 0.1$ dex spanning two and three orders of magnitude in size and number, respectively. This holds for both red and blue subpopulations, albeit with different slopes. Assuming that $N_{GC, Total}$ correlates with $M_{200}$, we find that the red GC systems have effective radii of roughly 1-5\% $R_{\rm 200}$, while the blue GC systems in massive galaxies can have sizes as large as $\sim$10\% $R_{\rm 200}$. Environmental dependence on $R_{e, \rm gc}$ is also found, with lower density environments exhibiting more extended GC systems at fixed mass., Comment: 28 pages, 18 Figures, 3 tables, accepted for publication in ApJ

Published
2024

7. FORECASTOR -- I. Finding Optics Requirements and Exposure times for the Cosmological Advanced Survey Telescope for Optical and UV Research mission

Author

Cheng, Isaac, Woods, Tyrone E., Côté, Patrick, Glover, Jennifer, Bansal, Dhananjhay, Amenouche, Melissa, Marshall, Madeline A., Amen, Laurie, Hutchings, John, Ferrarese, Laura, Venn, Kim A., Balogh, Michael, Blouin, Simon, Cloutier, Ryan, Dickson, Nolan, Gallagher, Sarah, Hellmich, Martin, Hénault-Brunet, Vincent, Khatu, Viraja, Lawlor-Forsyth, Cameron, Morgan, Cameron, Richer, Harvey, Sawicki, Marcin, and Sorba, Robert

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Astrophysics of Galaxies, Astrophysics - Solar and Stellar Astrophysics
Abstract

The Cosmological Advanced Survey Telescope for Optical and ultraviolet Research (CASTOR) is a proposed Canadian-led 1m-class space telescope that will carry out ultraviolet and blue-optical wide-field imaging, spectroscopy, and photometry. CASTOR will provide an essential bridge in the post-Hubble era, preventing a protracted UV-optical gap in space astronomy and enabling an enormous range of discovery opportunities from the solar system to the nature of the Cosmos, in conjunction with the other great wide-field observatories of the next decade (e.g., Euclid, Roman, Vera Rubin). FORECASTOR (Finding Optics Requirements and Exposure times for CASTOR) will supply a coordinated suite of mission-planning tools that will serve as the one-stop shop for proposal preparation, data reduction, and analysis for the CASTOR mission. We present the first of these tools: a pixel-based, user-friendly, extensible, multi-mission exposure time calculator (ETC) built in Python, including a modern browser-based graphical user interface that updates in real time. We then provide several illustrative examples of FORECASTOR's use that advance the design of planned legacy surveys for the CASTOR mission: a search for the most massive white dwarfs in the Magellanic Clouds; a study of the frequency of flaring activity in M stars, their distribution and impacts on habitability of exoplanets; mapping the proper motions of faint stars in the Milky Way; wide and deep galaxy surveys; and time-domain studies of active galactic nuclei., Comment: Updated references and acknowledgements to match published version. 24 pages, 16 figures, 3 tables, published in AJ

Published
2024
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8. The Next Generation Virgo Cluster Survey. XXXVII. Distant RR Lyrae Stars and the Milky Way Stellar Halo out to 300 kpc

Author

Feng, Yuting, Guhathakurta, Puragra, Peng, Eric W., Gwyn, Stephen D. J., Ferrarese, Laura, Côté, Patrick, Cuillandre, Jean-Charles, Munsell, Jeffrey, and Talukdar, Manjima

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

RR Lyrae stars are standard candles with characteristic photometric variability and serve as powerful tracers of Galactic structure, substructure, accretion history, and dark matter content. Here we report the discovery of distant RR Lyrae stars, including some of the most distant stars known in the Milky Way halo, with Galactocentric distances of approximately 300 kpc. We use time-series u*g'i'z' Canada-France-Hawaii Telescope/MegaCam photometry from the Next Generation Virgo Cluster Survey (NGVS). We employ a template light curve fitting method based on empirical Sloan Digital Sky Survey (SDSS) Stripe 82 RR Lyrae data to identify RR Lyrae candidates in the NGVS data set. We eliminate several hundred suspected quasars and identify 180 RR Lyrae candidates, with heliocentric distances of approximately 20--300 kpc. The halo stellar density distribution is consistent with an r^(-4.09 +/- 0.10) power-law radial profile over most of this distance range with no signs of a break. The distribution of ab-type RR Lyrae in a period-amplitude plot (Bailey diagram) suggests that the mean metallicity of the halo decreases outwards. Compared to other recent RR Lyrae surveys, like Pan-STARRS1 (PS1), the High Cadence Transient Survey (HiTS), and the Dark Energy Survey (DES), our NGVS study has better single-epoch photometric precision and a comparable number of epochs but smaller sky coverage. At large distances, our RR Lyrae sample appears to be relatively pure and complete, with well-measured periods and amplitudes. These newly discovered distant RR Lyrae stars are important additions to the few secure stellar tracers beyond 150 kpc in the Milky Way halo., Comment: Accepted by ApJ

Published
2024

9. EUSO-SPB1 Mission and Science

Author

Collaboration, JEM-EUSO, Abdellaoui, G., Abe, S., Adams. Jr., J. H., Allard, D., Alonso, G., Anchordoqui, L., Anzalone, A., Arnone, E., Asano, K., Attallah, R., Attoui, H., Pernas, M. Ave, Bachmann, R., Bacholle, S., Bagheri, M., Bakiri, M., Baláz, J., Barghini, D., Bartocci, S., Battisti, M., Bayer, J., Beldjilali, B., Belenguer, T., Belkhalfa, N., Bellotti, R., Belov, A. A., Benmessai, K., Bertaina, M., Bertone, P. F., Biermann, P. L., Bisconti, F., Blaksley, C., Blanc, N., Blin-Bondil, S., Bobik, P., Bogomilov, M., Bolmgren, K., Bozzo, E., Briz, S., Bruno, A., Caballero, K. S., Cafagna, F., Cambié, G., Campana, D., Capdevielle, J. N., Capel, F., Caramete, A., Caramete, L., Caruso, R., Casolino, M., Cassardo, C., Castellina, A., Catalano, O., Cellino, A., Černý, K., Chikawa, M., Chiritoi, G., Christl, M. J., Colalillo, R., Conti, L., Cotto, G., Crawford, H. J., Cremonini, R., Creusot, A., Cummings, A., Gónzalez, A. de Castro, de la Taille, C., del Peral, L., Desiato, J., Damian, A. Diaz, Diesing, R., Dinaucourt, P., Djakonow, A., Djemil, T., Ebersoldt, A., Ebisuzaki, T., Eser, J., Fenu, F., Fernández-González, S., Ferrarese, S., Filippatos, G., Finch, W., Fornaro, C., Fouka, M., Franceschi, A., Franchini, S., Fuglesang, C., Fujii, T., Fukushima, M., Galeotti, P., García-Ortega, E., Gardiol, D., Garipov, G. K., Gascón, E., Gazda, E., Genci, J., Golzio, A., Gorodetzky, P., Gregg, R., Green, A., Guarino, F., Guépin, C., Guzmán, A., Hachisu, Y., Haungs, A., Heigbes, T., Carretero, J. Hernández, Hulett, L., Ikeda, D., Inoue, N., Inoue, S., Isgrò, F., Itow, Y., Jammer, T., Jeong, S., Jochum, J., Joven, E., Judd, E. G., Jung, A., Kajino, F., Kajino, T., Kalli, S., Kaneko, I., Kasztelan, M., Katahira, K., Kawai, K., Kawasaki, Y., Kedadra, A., Khales, H., Khrenov, B. A., Kim, Jeong-Sook, Kim, Soon-Wook, Kleifges, M., Klimov, P. A., Kreykenbohm, I., Krizmanic, J. F., Królik, K., Kungel, V., Kurihara, Y., Kusenko, A., Kuznetsov, E., Lahmar, H., Lakhdari, F., Licandro, J., Campano, L. López, Martínez, F. López, Mackovjak, S., Mahdi, M., Mandát, D., Manfrin, M., Marcelli, L., Marcos, J. L., Marszał, W., Martín, Y., Martinez, O., Mase, K., Mastafa, M., Matthews, J. N., Mebarki, N., Medina-Tanco, G., Menshikov, A., Merino, A., Mese, M., Meseguer, J., Meyer, S. S., Mimouni, J., Miyamoto, H., Mizumoto, Y., Monaco, A., Ríos, J. A. Morales de los, Nachtman, J. M., Nagataki, S., Naitamor, S., Napolitano, T., Neronov, A., Nomoto, K., Nonaka, T., Ogawa, T., Ogio, S., Ohmori, H., Olinto, A. V., Onel, Y., Osteria, G., Otte, A. N., Pagliaro, A., Painter, W., Panasyuk, M. I., Panico, B., Parizot, E., Park, I. H., Pastircak, B., Paul, T., Pech, M., Pérez-Grande, I., Perfetto, F., Peter, T., Picozza, P., Pindado, S., Piotrowski, L. W., Piraino, S., Plebaniak, Z., Pollini, A., Popescu, E. M., Prevete, R., Prévôt, G., Prieto, H., Przybylak, M., Puehlhofer, G., Putis, M., Reardon, P., Reno, M. H., Reyes, M., Ricci, M., Frías, M. D. Rodríguez, Matamala, O. F. Romero, Ronga, F., Sabau, M. D., Saccá, G., Sagawa, H., Sahnoune, Z., Saito, A., Sakaki, N., Salazar, H., Sánchez, J. L., Balanzar, J. C. Sanchez, Santangelo, A., Sanz-Andrés, A., Saprykin, O. A., Sarazin, F., Sato, M., Scagliola, A., Schanz, T., Schieler, H., Schovánek, P., Scotti, V., Serra, M., Sharakin, S. A., Shimizu, H. M., Shinozaki, K., Soriano, J. F., Sotgiu, A., Stan, I., Strharský, I., Sugiyama, N., Supanitsky, D., Suzuki, M., Szabelski, J., Tajima, N., Tajima, T., Takahashi, Y., Takeda, M., Takizawa, Y., Talai, M. C., Tameda, Y., Tenzer, C., Thomas, S. B., Tibolla, O., Tkachev, L. G., Tomida, T., Tone, N., Toscano, S., Traïche, M., Tsunesada, Y., Tsuno, K., Turriziani, S., Uchihori, Y., Valdés-Galicia, J. F., Vallania, P., Valore, L., Vankova-Kirilova, G., Venters, T. M., Vigorito, C., Villaseñor, L., Vlcek, B., von Ballmoos, P., Vrabel, M., Wada, S., Watanabe, J., Watts. Jr., J., Muñoz, R. Weigand, Weindl, A., Wiencke, L., Wille, M., Wilms, J., Yamamoto, T., Yang, J., Yano, H., Yashin, I. V., Yonetoku, D., Yoshida, S., Young, R., Zgura, I. S., Zotov, M. Yu., and Marchi, A. Zuccaro

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena
Abstract

The Extreme Universe Space Observatory on a Super Pressure Balloon 1 (EUSO-SPB1) was launched in 2017 April from Wanaka, New Zealand. The plan of this mission of opportunity on a NASA super pressure balloon test flight was to circle the southern hemisphere. The primary scientific goal was to make the first observations of ultra-high-energy cosmic-ray extensive air showers (EASs) by looking down on the atmosphere with an ultraviolet (UV) fluorescence telescope from suborbital altitude (33~km). After 12~days and 4~hours aloft, the flight was terminated prematurely in the Pacific Ocean. Before the flight, the instrument was tested extensively in the West Desert of Utah, USA, with UV point sources and lasers. The test results indicated that the instrument had sensitivity to EASs of approximately 3 EeV. Simulations of the telescope system, telescope on time, and realized flight trajectory predicted an observation of about 1 event assuming clear sky conditions. The effects of high clouds were estimated to reduce this value by approximately a factor of 2. A manual search and a machine-learning-based search did not find any EAS signals in these data. Here we review the EUSO-SPB1 instrument and flight and the EAS search., Comment: 18 pages, 19 figures

Published
2024
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10. The dynamical state of bars in cluster dwarf galaxies: The cases of NGC 4483 and NGC 4516

Author

Cuomo, V., Morelli, L., Aguerri, J. A. L., Corsini, E. M., Debattista, V. P., Coccato, L., Pizzella, A., Boselli, A., Buttitta, C., de Lorenzo-Cáceres, A., Ferrarese, L., Gasparri, D., Lee, Y. H., Mendez-Abreu, J., Roediger, J., and Zarattini, S.

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

Dwarf barred galaxies are the perfect candidates for hosting slowly-rotating bars. They are common in dense environments and they have a relatively shallow potential well, making them prone to heating by interactions. When an interaction induces bar formation, the bar should rotate slowly. They reside in massive and centrally-concentrated dark matter halos, which slow down the bar rotation through dynamical friction. While predictions suggest that slow bars should be common, measurements of bar pattern speed, using the Tremaine-Weinberg method, show that bars are mostly fast in the local Universe. We present a photometric and kinematic characterisation of bars hosted by two dwarf galaxies in the Virgo Cluster, NGC 4483 and NGC 4516. We derive the bar length and strength using the Next Generation Virgo Survey imaging and the circular velocity, bar pattern speed, and rotation rate using spectroscopy from the Multi Unit Spectroscopic Explorer. Including the previously studied galaxy IC 3167, we compare the bar properties of the three dwarf galaxies with those of their massive counterparts from literature. Bars in the dwarf galaxies are shorter and weaker, and rotate slightly slower with respect to those in massive galaxies. This could be due to a different bar formation mechanism and/or to a large dark matter fraction in the centre of dwarf galaxies. We show that it is possible to push the application of the Tremaine-Weinberg method to the galaxy low mass regime., Comment: Accepted for publication in MNRAS

Published
2023

11. JEM-EUSO Collaboration contributions to the 38th International Cosmic Ray Conference

Author

Abe, S., Adams Jr., J. H., Allard, D., Alldredge, P., Aloisio, R., Anchordoqui, L., Anzalone, A., Arnone, E., Bagheri, M., Baret, B., Barghini, D., Battisti, M., Bellotti, R., Belov, A. A., Bertaina, M., Bertone, P. F., Bianciotto, M., Bisconti, F., Blaksley, C., Blin-Bondil, S., Bolmgren, K., Briz, S., Burton, J., Cafagna, F., Cambiè, G., Campana, D., Capel, F., Caruso, R., Casolino, M., Cassardo, C., Castellina, A., Černý, K., Christl, M. J., Colalillo, R., Conti, L., Cotto, G., Crawford, H. J., Cremonini, R., Creusot, A., Cummings, A., Gónzalez, A. de Castro, de la Taille, C., Diesing, R., Dinaucourt, P., Di Nola, A., Ebisuzaki, T., Eser, J., Fenu, F., Ferrarese, S., Filippatos, G., Finch, W. W., Flaminio, F., Fornaro, C., Fuehne, D., Fuglesang, C., Fukushima, M., Gadamsetty, S., Gardiol, D., Garipov, G. K., Gazda, E., Golzio, A., Guarino, F., Guépin, C., Haungs, A., Heibges, T., Isgrò, F., Judd, E. G., Kajino, F., Kaneko, I., Kim, S. -W., Klimov, P. A., Krizmanic, J. F., Kungel, V., Kuznetsov, E., Martínez, F. López, Mandát, D., Manfrin, M., Marcelli, A., Marcelli, L., Marszał, W., Matthews, J. N., Mese, M., Meyer, S. S., Mimouni, J., Miyamoto, H., Mizumoto, Y., Monaco, A., Nagataki, S., Nachtman, J. M., Naumov, D., Neronov, A., Nonaka, T., Ogawa, T., Ogio, S., Ohmori, H., Olinto, A. V., Onel, Y., Osteria, G., Otte, A. N., Pagliaro, A., Panico, B., Parizot, E., Park, I. H., Paul, T., Pech, M., Perfetto, F., Picozza, P., Piotrowski, L. W., Plebaniak, Z., Posligua, J., Potts, M., Prevete, R., Prévôt, G., Przybylak, M., Reali, E., Reardon, P., Reno, M. H., Ricci, M., Matamala, O. F. Romero, Romoli, G., Sagawa, H., Sakaki, N., Saprykin, O. A., Sarazin, F., Sato, M., Schovánek, P., Scotti, V., Selmane, S., Sharakin, S. A., Shinozaki, K., Stepanoff, S., Soriano, J. F., Szabelski, J., Tajima, N., Tajima, T., Takahashi, Y., Takeda, M., Takizawa, Y., Thomas, S. B., Tkachev, L. G., Tomida, T., Toscano, S., Traïche, M., Trofimov, D., Tsuno, K., Vallania, P., Valore, L., Venters, T. M., Vigorito, C., Vrábel, M., Wada, S., Watts Jr., J., Wiencke, L., Winn, D., Wistrand, H., Yashin, I. V., Young, R., and Zotov, M. Yu.

Subjects
Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

This is a collection of papers presented by the JEM-EUSO Collaboration at the 38th International Cosmic Ray Conference (Nagoya, Japan, July 26-August 3, 2023)

Published
2023

15. Supermassive black holes in a mass-limited galaxy sample

Author

Byrne, Zachary, Drinkwater, Michael J., Baumgardt, Holger, Blyth, David, Côté, Patrick, Lüetzgendorf, Nora, Spengler, Chelsea, Ferrarese, Laura, Mahajan, Smriti, Pfeffer, Joel, and Sweet, Sarah

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

The observed scaling relations between supermassive black hole masses and their host galaxy properties indicate that supermassive black holes influence the evolution of galaxies. However, the scaling relations may be affected by selection biases. We propose to measure black hole masses in a mass-limited galaxy sample including all non-detections to inprove constraints on galaxy mass - black hole mass scaling relations and test for selection bias. We use high spatial resolution spectroscopy from the Keck and Gemini telescopes, and the Jeans Anisotropic Modelling method to measure black hole masses in early type galaxies from the Virgo Cluster. We present four new black hole masses and one upper limit in our mass-selected sample of galaxies of galaxy mass (1.0-3.2) x $10^{10} M_\odot$. This brings the total measured to 11 galaxies out of a full sample of 18 galaxies, allowing us to constrain scaling relations. We calculate a lower limit for the average black hole mass in our sample of 3.7 x $10^{7} M_\odot$. This is at an average galaxy stellar mass of (1.81 +/- 0.14) x $10^{10} M_\odot $ and an average bulge mass of (1.31 +/- 0.15) x $10^{10} M_\odot$. This lower limit shows that black hole masses in early type galaxies are not strongly affected by selection biases.

Published
2023
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16. Developments and results in the context of the JEM-EUSO program obtained with the ESAF Simulation and Analysis Framework

Author

Abe, S., Adams Jr., J. H., Allard, D., Alldredge, P., Anchordoqui, L., Anzalone, A., Arnone, E., Baret, B., Barghini, D., Battisti, M., Bayer, J., Bellotti, R., Belov, A. A., Bertaina, M., Bertone, P. F., Bianciotto, M., Biermann, P. L., Bisconti, F., Blaksley, C., Blin-Bondil, S., Bobik, P., Bolmgren, K., Briz, S., Burton, J., Cafagna, F., Cambié, G., Campana, D., Capel, F., Caruso, R., Casolino, M., Cassardo, C., Castellina, A., Černý, K., Christl, M. J., Colalillo, R., Conti, L., Cotto, G., Crawford, H. J., Cremonini, R., Creusot, A., Cummings, A., Gónzalez, A. de Castro, de la Taille, C., del Peral, L., Diesing, R., Dinaucourt, P., Di Nola, A., Ebersoldt, A., Ebisuzaki, T., Eser, J., Fenu, F., Ferrarese, S., Filippatos, G., Finch, W. W., Flaminio, F., Fornaro, C., Fuehne, D., Fuglesang, C., Fukushima, M., Gardiol, D., Garipov, G. K., Golzio, A., Gorodetzky, P., Guarino, F., Guépin, C., Guzmán, A., Haungs, A., Heibges, T., Hernández-Carretero, J., Isgrò, F., Judd, E. G., Kajino, F., Kaneko, I., Kawasaki, Y., Kleifges, M., Klimov, P. A., Kreykenbohm, I., Krizmanic, J. F., Kungel, V., Kuznetsov, E., Martínez, F. López, Mackovjak, S., Mandát, D., Manfrin, M., Marcelli, A., Marcelli, L., Marszał, W., Matthews, J. N., Menshikov, A., Mernik, T., Mese, M., Meyer, S. S., Mimouni, J., Miyamoto, H., Mizumoto, Y., Monaco, A., Ríos, J. A Morales de los, Nagataki, S., Nachtman, J. M., Naumov, D., Neronov, A., Nonaka, T., Ogawa, T., Ogio, S., Ohmori, H., Olinto, A. V., Onel, Y., Osteria, G., Pagliaro, A., Panico, B., Parizot, E., Park, I. H., Pastircak, B., Paul, T., Pech, M., Perfetto, F., Picozza, P., Piotrowski, L. W., Plebaniak, Z., Posligua, J., Prevete, R., Prévôt, G., Prieto, H., Przybylak, M., Putis, M., Reali, E., Reardon, P., Reno, M. H., Ricci, M., Frías, M. Rodríguez, Romoli, G., Cano, G. Sáez, Sagawa, H., Sakaki, N., Santangelo, A., Saprykin, O. A., Sarazin, F., Sato, M., Schieler, H., Schovánek, P., Scotti, V., Selmane, S., Sharakin, S. A., Shinozaki, K., Soriano, J. F., Szabelski, J., Tajima, N., Tajima, T., Takahashi, Y., Takeda, M., Takizawa, Y., Tenzer, C., Thomas, S. B., Tkachev, L. G., Tomida, T., Toscano, S., Traïche, M., Trofimov, D., Tsuno, K., Vallania, P., Valore, L., Venters, T. M., Vigorito, C., von Ballmoos, P., Vrabel, M., Wada, S., Watts Jr., J., Weindl, A., Wiencke, L., Wilms, J., Winn, D., Wistrand, H., Yashin, I. V., Young, R., and Zotov, M. Yu.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, High Energy Physics - Experiment
Abstract

JEM--EUSO is an international program for the development of space-based Ultra-High Energy Cosmic Ray observatories. The program consists of a series of missions which are either under development or in the data analysis phase. All instruments are based on a wide-field-of-view telescope, which operates in the near-UV range, designed to detect the fluorescence light emitted by extensive air showers in the atmosphere. We describe the simulation software ESAFin the framework of the JEM--EUSO program and explain the physical assumptions used. We present here the implementation of the JEM--EUSO, POEMMA, K--EUSO, TUS, Mini--EUSO, EUSO--SPB1 and EUSO--TA configurations in ESAF. For the first time ESAF simulation outputs are compared with experimental data.

Published
2023
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17. An evolutionary continuum from nucleated dwarf galaxies to star clusters

Author

Wang, Kaixiang, Peng, Eric W., Liu, Chengze, Mihos, J. Christopher, Côté, Patrick, Ferrarese, Laura, Taylor, Matthew A., Blakeslee, John P., Cuillandre, Jean-Charles, Duc, Pierre-Alain, Guhathakurta, Puragra, Gwyn, Stephen, Ko, Youkyung, Lançon, Ariane, Lim, Sungsoon, MacArthur, Lauren A., Puzia, Thomas, Roediger, Joel, Sales, Laura V., Sánchez-Janssen, Rubén, Spengler, Chelsea, Toloba, Elisa, Zhang, Hongxin, and Zhu, Mingcheng

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

Systematic studies have revealed hundreds of ultra-compact dwarf galaxies (UCDs) in the nearby Universe. With half-light radii $r_h$ of approximately 10-100 parsecs and stellar masses $M_*$ $\approx$ $10^6-10^8$ solar masses, UCDs are among the densest known stellar systems. Although similar in appearance to massive globular clusters, the detection of extended stellar envelopes, complex star formation histories, elevated mass-to-light ratio, and supermassive black holes suggest that some UCDs are remnant nuclear star clusters of tidally-stripped dwarf galaxies, or even ancient compact galaxies. However, only a few objects have been found in the transient stage of tidal stripping, and this assumed evolutionary path has never been fully traced by observations. Here we show that 106 galaxies in the Virgo cluster have morphologies that are intermediate between normal, nucleated dwarf galaxies and single-component UCDs, revealing a continuum that fully maps this morphological transition, and fills the `size gap' between star clusters and galaxies. Their spatial distribution and redder color are also consistent with stripped satellite galaxies on their first few pericentric passages around massive galaxies. The `ultra-diffuse' tidal features around several of these galaxies directly show how UCDs are forming through tidal stripping, and that this evolutionary path can include an early phase as a nucleated ultra-diffuse galaxy (UDG). These UCDs represent substantial visible fossil remnants of ancient dwarf galaxies in galaxy clusters, and more low-mass remnants probably remain to be found., Comment: Published in Nature. Accepted on September 15

Published
2023
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18. Rapidly Progressive Dementia Due To Primary Central Nervous System Lymphoma: A Case Report

Author

Eduardo Magalhães da Costa, Alessandra Ferrarese Barbosa, Camila Pourbaix Morisson Ferreira, Mariangela Perez, Roberto Alves Lourenço, Monique de França Silva, and Flávio Assad Garcia

Subjects
mental status and dementia tests, lymphoma, elderly, Nursing, RT1-120, Geriatrics, RC952-954.6, Public aspects of medicine, RA1-1270
Abstract

Rapidly progressive dementias are conditions that worsening the patient’s life; however they are not always considered during the investigation of dementia syndrome. This report describes the case of a patient with rheumatoid arthritis and chronic use of corticosteroid therapy, who developed rapidly progressive dementia within 5 months. During the investigation, the primary lymphoma of the central nervous system was evidenced as the cause of its dementia syndrome. Importantly, prolonged use of corticosteroids may be associated with a state of immunosuppression, which is a risk factor for the onset of central nervous system lymphoma.

Published
2024
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19. Internal Consistency and Floor/Ceiling Effects of the Gross Motor Function Measure for Use with Children Affected by Cancer: A Cross-Sectional Study

Author

Francesca Rossi, Monica Valle, Giovanni Galeoto, Marco Tofani, Paola Berchialla, Veronica Sciannameo, Daniele Bertin, Annalisa Calcagno, Roberto Casalaz, Margherita Cerboneschi, Marta Cervo, Annalisa Cornelli, Chiara Di Pede, Maria Esposito, Miriana Ferrarese, Paola Imazio, Maria Lorenzon, Lucia Longo, Andrea Martinuzzi, Gabriella Naretto, Nicoletta Orsini, Daniele Panzeri, Chiara Pellegrini, Michela Peranzoni, Fabiola Picone, Marco Rabusin, Federica Ricci, Claudia Zigrino, Giulia Zucchetti, and Franca Fagioli

Subjects
physical therapy, rehabilitative evaluation, GMFM-88, pediatric oncology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Children/adolescents with cancer can develop adverse effects impacting gross motor function. There is a lack of gross motor function assessment tools that have been validated for this population. The aim of this multicenter cross-sectional study was to preliminary validate the 88-item Gross Motor Function Measure (GMFM-88) for use in children/adolescents with cancer, exploring internal consistency and floor/ceiling effect. Inclusion criteria regarded children/adolescents diagnosed with cancer on treatment or

Published
2024
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20. Kinetic description of swarming dynamics with topological interaction and transient leaders

Author

Albi, Giacomo and Ferrarese, Federica

Subjects
Mathematics - Numerical Analysis, Quantitative Biology - Populations and Evolution
Abstract

In this paper, we present a model describing the collective motion of birds. The model introduces spontaneous changes in direction which are initialized by few agents, here referred as leaders, whose influence act on their nearest neighbors, in the following referred as followers. Starting at the microscopic level, we develop a kinetic model that characterizes the behaviour of large flocks with transient leadership. One significant challenge lies in managing topological interactions, as identifying nearest neighbors in extensive systems can be computationally expensive. To address this, we propose a novel stochastic particle method to simulate the mesoscopic dynamics and reduce the computational cost of identifying closer agents from quadratic to logarithmic complexity using a $k$-nearest neighbours search algorithm with a binary tree. Lastly, we conduct various numerical experiments for different scenarios to validate the algorithm's effectiveness and investigate collective dynamics in both two and three dimensions.

Published
2023

21. Gathering Galaxy Distances in Abundance with Roman Wide-Area Data

Author

Blakeslee, John P., Cantiello, Michele, Hudson, Michael J., Ferrarese, Laura, Hazra, Nandini, Jensen, Joseph B., Peng, Eric W., and Raimondo, Gabriella

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - Astrophysics of Galaxies
Abstract

The extragalactic distance scale is fundamental to our understanding of astrophysics and cosmology. In recent years, the surface brightness fluctuation (SBF) method, applied in the near-IR, has proven especially powerful for measuring galaxy distances, first with HST and now with a new JWST program to calibrate the method directly from the tip of the red giant branch (TRGB). So far, however, the distances from space have been gathered slowly, one or two at a time. With the Roman Space Telescope, we have the opportunity to measure uniformly high-quality SBF distances to thousands of galaxies out to hundreds of Mpc. The impact of these data on cosmology and galaxy studies depends on the specifics of the survey, including the filter selection, exposure depth, and (especially) the sky coverage. While the baseline HLWAS survey in four filters plus the grism would yield useful data, the impact would be limited by the relatively small area. A more optimal approach would concentrate on the most efficient passband (F146), adopt an exposure time sufficient to measure good quality distances well out into the Hubble flow, and then maximize the sky coverage within the total time constraints. Grism observations over the same area can provide the needed information on redshifts and spectral energy distributions for compact sources, while colors for larger objects can be obtained from lower resolution surveys. The proposed plan will enable accurate determination of the physical properties of thousands of nearby galaxies, an independent measure of the Hubble constant $H_0$ with negligible statistical error, and competitive constraints on $S_8{\,=\,}\sigma_8(\Omega_m/0.3)^{0.5}$. The resulting data set will be a phenomenal resource for a wide range of studies in astrophysics and cosmology., Comment: 5 pages; submitted to the call for Roman Core Community Survey white papers (revised version corrects a couple references)

Published
2023

22. ViCTORIA project: MeerKAT HI observations of the ram pressure stripped galaxy NGC 4523

Author

Boselli, A., Serra, P., de Gasperin, F., Vollmer, B., Amram, P., Edler, H. W., Fossati, M., Consolandi, G., Cote, P., Cuillandre, J. C., Ferrarese, L., Gwyn, S., Postma, J., Boquien, M., Braine, J., Combes, F., Gavazzi, G., Hensler, G., Miville-Deschenes, M. A., Murgia, M., Roediger, J., Roehlly, Y., Smith, R., Zhang, H. X., and Zabel, N.

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

We present the first results of a 21 cm HI line pilot observation carried out with MeerKAT in preparation for the ViCTORIA project, an untargeted survey of the Virgo galaxy cluster. The extraordinary quality of the data in terms of sensitivity and angular resolution (rms~0.65 mJy beam^-1 at ~27"x39" and 11 km/s resolution) allowed us to detect an extended (~10 kpc projected length) low column density (N(HI) < 2.5x10^20 cm^-2) HI gas tail associated with the dwarf irregular galaxy NGC4523 at the northern edge of the cluster. The morphology of the tail and of the stellar disc suggest that the galaxy is suffering a hydrodynamic interaction with the surrounding hot intracluster medium (ICM; ram pressure stripping). The orientation of the trailing tail, the gradient in the HI gas column density at the interface between the cold ISM and the hot ICM, the velocity of the galaxy with respect to that of the cluster, and its position indicate that NGC4523 is infalling for the first time into Virgo from the NNW background of the cluster. Using a grid of hydrodynamic simulations we derive the impact parameters with the surrounding ICM, and estimate that the galaxy will be at pericentre (D~500-600 kpc) in ~1 Gyr, where ram pressure stripping will be able to remove most, if not all, of its gas. The galaxy is located on the star formation main sequence when its star formation rate is derived using Halpha images obtained during the VESTIGE survey, suggesting that NGC4523 is only at the beginning of its interaction with the surrounding environment. A few HII regions are detected in the Halpha images within the HI gas tail outside the stellar disc. Their ages, derived by comparing their Halpha, FUV, NUV, and optical colours with the predictions of SED fitting models, are <30 Myr, and suggest that these HII regions have formed within the stripped gas., Comment: Accepted for publication in A&A

Published
2023
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23. Kinetic based optimization enhanced by genetic dynamics

Author

Albi, Giacomo, Ferrarese, Federica, and Totzeck, Claudia

Subjects
Mathematics - Optimization and Control, Mathematics - Numerical Analysis
Abstract

We propose and analyse a variant of the recently introduced kinetic based optimization method that incorporates ideas like survival-of-the-fittest and mutation strategies well-known from genetic algorithms. Thus, we provide a first attempt to reach out from the class of consensus/kinetic-based algorithms towards genetic metaheuristics. Different generations of genetic algorithms are represented via two species identified with different labels, binary interactions are prescribed on the particle level and then we derive a mean-field approximation in order to analyse the method in terms of convergence. Numerical results underline the feasibility of the approach and show in particular that the genetic dynamics allows to improve the efficiency, of this class of global optimization methods in terms of computational cost.

Published
2023

24. The Near Infrared Imager and Slitless Spectrograph for the James Webb Space Telescope -- I. Instrument Overview and in-Flight Performance

Author

Doyon, Rene, Willott, C. J, Hutchings, John B., Sivaramakrishnan, Anand, Albert, Loic, Lafreniere, David, Rowlands, Neil, Vila, M. Begona, Martel, Andre R., LaMassa, Stephanie, Aldridge, David, Artigau, Etienne, Cameron, Peter, Chayer, Pierre, Cook, Neil J., Cooper, Rachel A., Darveau-Bernier, Antoine, Dupuis, Jean, Earnshaw, Colin, Espinoza, Nestor, Filippazzo, Joseph C., Fullerton, Alexander W., Gaudreau, Daniel, Gawlik, Roman, Goudfrooij, Paul, Haley, Craig, Kammerer, Jens, Kendall, David, Lambros, Scott D., Ignat, Luminita Ilinca, Maszkiewicz, Michael, McColgan, Ashley, Morishita, Takahiro, Ouellette, Nathalie N. -Q., Pacifici, Camilla, Philippi, Natasha, Radica, Michael, Ravindranath, Swara, Rowe, Jason, Roy, Arpita, Saad, Karl, Sohn, Sangmo Tony, Talens, Geert Jan, Thatte, Deepashri, Taylor, Joanna M., Vandal, Thomas, Volk, Kevin, Wander, Michel, Warner, Gerald, Zheng, Sheng-Hai, Zhou, Julia, Abraham, Roberto, Beaulieu, Mathilde, Benneke, Bjorn, Ferrarese, Laura, Johnstone, Doug, Kaltenegger, Lisa, Meyer, Michael R., Pipher, Judy L., Rameau, Julien, Rieke, Marcia, Salhi, Salma, and Sawicki, Marcin

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

The Near-Infrared Imager and Slitless Spectrograph (NIRISS) is the science module of the Canadian-built Fine Guidance Sensor (FGS) onboard the James Webb Space Telescope (JWST). NIRISS has four observing modes: 1) broadband imaging featuring seven of the eight NIRCam broadband filters, 2) wide-field slitless spectroscopy (WFSS) at a resolving power of $\sim$150 between 0.8 and 2.2 $\mu$m, 3) single-object cross-dispersed slitless spectroscopy (SOSS) enabling simultaneous wavelength coverage between 0.6 and 2.8 $\mu$m at R$\sim$700, a mode optimized for exoplanet spectroscopy of relatively bright ($J<6.3$) stars and 4) aperture masking interferometry (AMI) between 2.8 and 4.8 $\mu$m enabling high-contrast ($\sim10^{-3}-10^{-4}$) imaging at angular separations between 70 and 400 milliarcsec for relatively bright ($M<8$) sources. This paper presents an overview of the NIRISS instrument, its design, its scientific capabilities, and a summary of in-flight performance. NIRISS shows significantly better response shortward of $\sim2.5\,\mu$m resulting in 10-40% sensitivity improvement for broadband and low-resolution spectroscopy compared to pre-flight predictions. Two time-series observations performed during instrument commissioning in the SOSS mode yield very stable spectro-photometry performance within $\sim$10% of the expected noise. The first space-based companion detection of the tight binary star AB Dor AC through AMI was demonstrated.

Published
2023

32. A Virgo Environmental Survey Tracing Ionised Gas Emission (VESTIGE) XV. The Halpha luminosity function of the Virgo cluster

Author

Boselli, A., Fossati, M., Cote, P., Cuillandre, J. C., Ferrarese, L., Gwyn, S., Amram, P., Ayromlou, M., Balogh, M., Bellusci, G., Boquien, M., Gavazzi, G., Hensler, G., Longobardi, A., Nelson, D., Pillepich, A., Roediger, J., Sanchez-Jansen, R., Sun, M., and Trinchieri, G.

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

We use a complete set of deep narrow-band imaging data for 384 galaxies gathered during the VESTIGE survey to derive the first Halpha luminosity function (LF) of the Virgo cluster within R200. The data allow us to cover the whole dynamic range of the Halpha LF (10^3610^14 Mo. The comparison with the IllustrisTNG cosmological hydrodynamical simulations shows a more pronounced decrease at the faint end of the distribution. If Virgo is representative of typical nearby clusters of similar mass, this difference suggests that the stripping process in simulated galaxies in these environments is more efficient than observed., Comment: Accepted for publication on A&A

Published
2023
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33. The Next Generation Virgo Cluster Survey (NGVS). XXXV. First Kinematical Clues of Overly-Massive Dark Matter Halos in Several Ultra-Diffuse Galaxies in the Virgo Cluster

Author

Toloba, Elisa, Sales, Laura V., Lim, Sungsoon, Peng, Eric W., Guhathakurta, Puragra, Roediger, Joel, Wang, Kaixiang, Mihos, J. Christopher, Cote, Patrick, Durrell, Patrick R., and Ferrarese, Laura

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

We present Keck/DEIMOS spectroscopy of the first complete sample of ultra-diffuse galaxies (UDGs) in the Virgo cluster. We select all UDGs in Virgo that contain at least 10 globular cluster (GC) candidates and are more than $2.5\sigma$ outliers in scaling relations of size, surface brightness, and luminosity (a total of 10 UDGs). We use the radial velocity of their GC satellites to measure the velocity dispersion of each UDG. We find a mixed bag of galaxies: from one UDG that shows no signs of dark matter, to UDGs that follow the luminosity-dispersion relation of early-type galaxies, to the most extreme examples of heavily dark matter dominated galaxies that break well-known scaling relations such as the luminosity-dispersion or the U-shaped total mass-to-light ratio relations. This is indicative of a number of mechanisms at play forming these peculiar galaxies. Some of them may be the most extended version of dwarf galaxies, while others are so extreme that they seem to populate dark matter halos consistent with that of the Milky-Way or even larger. Even though Milky-Way stars and other GC interlopers contaminating our sample of GCs cannot be fully ruled-out, our assessment of this potential problem and simulations indicate that the probability is low and, if present, unlikely to be enough to explain the extreme dispersions measured. Further confirmation from stellar kinematics studies in these UDGs would be desirable. The lack of such extreme objects in any of the state-of-the-art simulations, opens an exciting avenue of new physics shaping these galaxies., Comment: 27 pages, 12 figures. Accepted for publication in ApJ

Published
2023
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34. The James Webb Space Telescope Mission

Author

Gardner, Jonathan P., Mather, John C., Abbott, Randy, Abell, James S., Abernathy, Mark, Abney, Faith E., Abraham, John G., Abraham, Roberto, Abul-Huda, Yasin M., Acton, Scott, Adams, Cynthia K., Adams, Evan, Adler, David S., Adriaensen, Maarten, Aguilar, Jonathan Albert, Ahmed, Mansoor, Ahmed, Nasif S., Ahmed, Tanjira, Albat, Rüdeger, Albert, Loïc, Alberts, Stacey, Aldridge, David, Allen, Mary Marsha, Allen, Shaune S., Altenburg, Martin, Altunc, Serhat, Alvarez, Jose Lorenzo, Álvarez-Márquez, Javier, de Oliveira, Catarina Alves, Ambrose, Leslie L., Anandakrishnan, Satya M., Andersen, Gregory C., Anderson, Harry James, Anderson, Jay, Anderson, Kristen, Anderson, Sara M., Aprea, Julio, Archer, Benita J., Arenberg, Jonathan W., Argyriou, Ioannis, Arribas, Santiago, Artigau, Étienne, Arvai, Amanda Rose, Atcheson, Paul, Atkinson, Charles B., Averbukh, Jesse, Aymergen, Cagatay, Bacinski, John J., Baggett, Wayne E., Bagnasco, Giorgio, Baker, Lynn L., Balzano, Vicki Ann, Banks, Kimberly A., Baran, David A., Barker, Elizabeth A., Barrett, Larry K., Barringer, Bruce O., Barto, Allison, Bast, William, Baudoz, Pierre, Baum, Stefi, Beatty, Thomas G., Beaulieu, Mathilde, Bechtold, Kathryn, Beck, Tracy, Beddard, Megan M., Beichman, Charles, Bellagama, Larry, Bely, Pierre, Berger, Timothy W., Bergeron, Louis E., Darveau-Bernier, Antoine, Bertch, Maria D., Beskow, Charlotte, Betz, Laura E., Biagetti, Carl P., Birkmann, Stephan, Bjorklund, Kurt F., Blackwood, James D., Blazek, Ronald Paul, Blossfeld, Stephen, Bluth, Marcel, Boccaletti, Anthony, Boegner Jr., Martin E., Bohlin, Ralph C., Boia, John Joseph, Böker, Torsten, Bonaventura, N., Bond, Nicholas A., Bosley, Kari Ann, Boucarut, Rene A., Bouchet, Patrice, Bouwman, Jeroen, Bower, Gary, Bowers, Ariel S., Bowers, Charles W., Boyce, Leslye A., Boyer, Christine T., Boyer, Martha L., Boyer, Michael, Boyer, Robert, Bradley, Larry D., Brady, Gregory R., Brandl, Bernhard R., Brannen, Judith L., Breda, David, Bremmer, Harold G., Brennan, David, Bresnahan, Pamela A., Bright, Stacey N., Broiles, Brian J., Bromenschenkel, Asa, Brooks, Brian H., Brooks, Keira J., Brown, Bob, Brown, Bruce, Brown, Thomas M., Bruce, Barry W., Bryson, Jonathan G., Bujanda, Edwin D., Bullock, Blake M., Bunker, A. J., Bureo, Rafael, Burt, Irving J., Bush, James Aaron, Bushouse, Howard A., Bussman, Marie C., Cabaud, Olivier, Cale, Steven, Calhoon, Charles D., Calvani, Humberto, Canipe, Alicia M., Caputo, Francis M., Cara, Mihai, Carey, Larkin, Case, Michael Eli, Cesari, Thaddeus, Cetorelli, Lee D., Chance, Don R., Chandler, Lynn, Chaney, Dave, Chapman, George N., Charlot, S., Chayer, Pierre, Cheezum, Jeffrey I., Chen, Bin, Chen, Christine H., Cherinka, Brian, Chichester, Sarah C., Chilton, Zachary S., Chittiraibalan, Dharini, Clampin, Mark, Clark, Charles R., Clark, Kerry W., Clark, Stephanie M., Claybrooks, Edward E., Cleveland, Keith A., Cohen, Andrew L., Cohen, Lester M., Colón, Knicole D., Coleman, Benee L., Colina, Luis, Comber, Brian J., Comeau, Thomas M., Comer, Thomas, Reis, Alain Conde, Connolly, Dennis C., Conroy, Kyle E., Contos, Adam R., Contreras, James, Cook, Neil J., Cooper, James L., Cooper, Rachel Aviva, Correia, Michael F., Correnti, Matteo, Cossou, Christophe, Costanza, Brian F., Coulais, Alain, Cox, Colin R., Coyle, Ray T., Cracraft, Misty M., Noriega-Crespo, Alberto, Crew, Keith A., Curtis, Gary J., Cusveller, Bianca, Maciel, Cleyciane Da Costa, Dailey, Christopher T., Daugeron, Frédéric, Davidson, Greg S., Davies, James E., Davis, Katherine Anne, Davis, Michael S., Day, Ratna, de Chambure, Daniel, de Jong, Pauline, De Marchi, Guido, Dean, Bruce H., Decker, John E., Delisa, Amy S., Dell, Lawrence C., Dellagatta, Gail, Dembinska, Franciszka, Demosthenes, Sandor, Dencheva, Nadezhda M., Deneu, Philippe, DePriest, William W., Deschenes, Jeremy, Dethienne, Nathalie, Detre, Örs Hunor, Diaz, Rosa Izela, Dicken, Daniel, DiFelice, Audrey S., Dillman, Matthew, Disharoon, Maureen O., van Dishoeck, Ewine F., Dixon, William V., Doggett, Jesse B., Dominguez, Keisha L., Donaldson, Thomas S., Doria-Warner, Cristina M., Santos, Tony Dos, Doty, Heather, Douglas Jr., Robert E., Doyon, René, Dressler, Alan, Driggers, Jennifer, Driggers, Phillip A., Dunn, Jamie L., DuPrie, Kimberly C., Dupuis, Jean, Durning, John, Dutta, Sanghamitra B., Earl, Nicholas M., Eccleston, Paul, Ecobichon, Pascal, Egami, Eiichi, Ehrenwinkler, Ralf, Eisenhamer, Jonathan D., Eisenhower, Michael, Eisenstein, Daniel J., Hamel, Zaky El, Elie, Michelle L., Elliott, James, Elliott, Kyle Wesley, Engesser, Michael, Espinoza, Néstor, Etienne, Odessa, Etxaluze, Mireya, Evans, Leah, Fabreguettes, Luce, Falcolini, Massimo, Falini, Patrick R., Fatig, Curtis, Feeney, Matthew, Feinberg, Lee D., Fels, Raymond, Ferdous, Nazma, Ferguson, Henry C., Ferrarese, Laura, Ferreira, Marie-Héléne, Ferruit, Pierre, Ferry, Malcolm, Filippazzo, Joseph Charles, Firre, Daniel, Fix, Mees, Flagey, Nicolas, Flanagan, Kathryn A., Fleming, Scott W., Florian, Michael, Flynn, James R., Foiadelli, Luca, Fontaine, Mark R., Fontanella, Erin Marie, Forshay, Peter Randolph, Fortner, Elizabeth A., Fox, Ori D., Framarini, Alexandro P., Francisco, John I., Franck, Randy, Franx, Marijn, Franz, David E., Friedman, Scott D., Friend, Katheryn E., Frost, James R., Fu, Henry, Fullerton, Alexander W., Gaillard, Lionel, Galkin, Sergey, Gallagher, Ben, Galyer, Anthony D., Marín, Macarena García, Gardner, Lisa E., Garland, Dennis, Garrett, Bruce Albert, Gasman, Danny, Gáspár, András, Gastaud, René, Gaudreau, Daniel, Gauthier, Peter Timothy, Geers, Vincent, Geithner, Paul H., Gennaro, Mario, Gerber, John, Gereau, John C., Giampaoli, Robert, Giardino, Giovanna, Gibbons, Paul C., Gilbert, Karolina, Gilman, Larry, Girard, Julien H., Giuliano, Mark E., Gkountis, Konstantinos, Glasse, Alistair, Glassmire, Kirk Zachary, Glauser, Adrian Michael, Glazer, Stuart D., Goldberg, Joshua, Golimowski, David A., Gonzaga, Shireen P., Gordon, Karl D., Gordon, Shawn J., Goudfrooij, Paul, Gough, Michael J., Graham, Adrian J., Grau, Christopher M., Green, Joel David, Greene, Gretchen R., Greene, Thomas P., Greenfield, Perry E., Greenhouse, Matthew A., Greve, Thomas R., Greville, Edgar M., Grimaldi, Stefano, Groe, Frank E., Groebner, Andrew, Grumm, David M., Grundy, Timothy, Güdel, Manuel, Guillard, Pierre, Guldalian, John, Gunn, Christopher A., Gurule, Anthony, Gutman, Irvin Meyer, Guy, Paul D., Guyot, Benjamin, Hack, Warren J., Haderlein, Peter, Hagan, James B., Hagedorn, Andria, Hainline, Kevin, Haley, Craig, Hami, Maryam, Hamilton, Forrest Clifford, Hammann, Jeffrey, Hammel, Heidi B., Hanley, Christopher J., Hansen, Carl August, Hardy, Bruce, Harnisch, Bernd, Harr, Michael Hunter, Harris, Pamela, Hart, Jessica Ann, Hartig, George F., Hasan, Hashima, Hashim, Kathleen Marie, Hashimoto, Ryan, Haskins, Sujee J., Hawkins, Robert Edward, Hayden, Brian, Hayden, William L., Healy, Mike, Hecht, Karen, Heeg, Vince J., Hejal, Reem, Helm, Kristopher A., Hengemihle, Nicholas J., Henning, Thomas, Henry, Alaina, Henry, Ronald L., Henshaw, Katherine, Hernandez, Scarlin, Herrington, Donald C., Heske, Astrid, Hesman, Brigette Emily, Hickey, David L., Hilbert, Bryan N., Hines, Dean C., Hinz, Michael R., Hirsch, Michael, Hitcho, Robert S., Hodapp, Klaus, Hodge, Philip E., Hoffman, Melissa, Holfeltz, Sherie T., Holler, Bryan Jason, Hoppa, Jennifer Rose, Horner, Scott, Howard, Joseph M., Howard, Richard J., Huber, Jean M., Hunkeler, Joseph S., Hunter, Alexander, Hunter, David Gavin, Hurd, Spencer W., Hurst, Brendan J., Hutchings, John B., Hylan, Jason E., Ignat, Luminita Ilinca, Illingworth, Garth, Irish, Sandra M., Isaacs III, John C., Jackson Jr., Wallace C., Jaffe, Daniel T., Jahic, Jasmin, Jahromi, Amir, Jakobsen, Peter, James, Bryan, James, John C., James, LeAndrea Rae, Jamieson, William Brian, Jandra, Raymond D., Jayawardhana, Ray, Jedrzejewski, Robert, Jeffers, Basil S., Jensen, Peter, Joanne, Egges, Johns, Alan T., Johnson, Carl A., Johnson, Eric L., Johnson, Patricia, Johnson, Phillip Stephen, Johnson, Thomas K., Johnson, Timothy W., Johnstone, Doug, Jollet, Delphine, Jones, Danny P., Jones, Gregory S., Jones, Olivia C., Jones, Ronald A., Jones, Vicki, Jordan, Ian J., Jordan, Margaret E., Jue, Reginald, Jurkowski, Mark H., Justis, Grant, Justtanont, Kay, Kaleida, Catherine C., Kalirai, Jason S., Kalmanson, Phillip Cabrales, Kaltenegger, Lisa, Kammerer, Jens, Kan, Samuel K., Kanarek, Graham Childs, Kao, Shaw-Hong, Karakla, Diane M., Karl, Hermann, Kassin, Susan A., Kauffman, David D., Kavanagh, Patrick, Kelley, Leigh L., Kelly, Douglas M., Kendrew, Sarah, Kennedy, Herbert V., Kenny, Deborah A., Keski-Kuha, Ritva A., Keyes, Charles D., Khan, Ali, Kidwell, Richard C., Kimble, Randy A., King, James S., King, Richard C., Kinzel, Wayne M., Kirk, Jeffrey R., Kirkpatrick, Marc E., Klaassen, Pamela, Klingemann, Lana, Klintworth, Paul U., Knapp, Bryan Adam, Knight, Scott, Knollenberg, Perry J., Knutsen, Daniel Mark, Koehler, Robert, Koekemoer, Anton M., Kofler, Earl T., Kontson, Vicki L., Kovacs, Aiden Rose, Kozhurina-Platais, Vera, Krause, Oliver, Kriss, Gerard A., Krist, John, Kristoffersen, Monica R., Krogel, Claudia, Krueger, Anthony P., Kulp, Bernard A., Kumari, Nimisha, Kwan, Sandy W., Kyprianou, Mark, Labador, Aurora Gadiano, Labiano, Álvaro, Lafrenière, David, Lagage, Pierre-Olivier, Laidler, Victoria G., Laine, Benoit, Laird, Simon, Lajoie, Charles-Philippe, Lallo, Matthew D., Lam, May Yen, LaMassa, Stephanie Marie, Lambros, Scott D., Lampenfield, Richard Joseph, Lander, Matthew Ed, Langston, James Hutton, Larson, Kirsten, Larson, Melora, LaVerghetta, Robert Joseph, Law, David R., Lawrence, Jon F., Lee, David W., Lee, Janice, Lee, Yat-Ning Paul, Leisenring, Jarron, Leveille, Michael Dunlap, Levenson, Nancy A., Levi, Joshua S., Levine, Marie B., Lewis, Dan, Lewis, Jake, Lewis, Nikole, Libralato, Mattia, Lidon, Norbert, Liebrecht, Paula Louisa, Lightsey, Paul, Lilly, Simon, Lim, Frederick C., Lim, Pey Lian, Ling, Sai-Kwong, Link, Lisa J., Link, Miranda Nicole, Lipinski, Jamie L., Liu, XiaoLi, Lo, Amy S., Lobmeyer, Lynette, Logue, Ryan M., Long, Chris A., Long, Douglas R., Long, Ilana D., Long, Knox S., López-Caniego, Marcos, Lotz, Jennifer M., Love-Pruitt, Jennifer M., Lubskiy, Michael, Luers, Edward B., Luetgens, Robert A., Luevano, Annetta J., Lui, Sarah Marie G. Flores, Lund III, James M., Lundquist, Ray A., Lunine, Jonathan, Lützgendorf, Nora, Lynch, Richard J., MacDonald, Alex J., MacDonald, Kenneth, Macias, Matthew J., Macklis, Keith I., Maghami, Peiman, Maharaja, Rishabh Y., Maiolino, Roberto, Makrygiannis, Konstantinos G., Malla, Sunita Giri, Malumuth, Eliot M., Manjavacas, Elena, Marini, Andrea, Marrione, Amanda, Marston, Anthony, Martel, André R, Martin, Didier, Martin, Peter G., Martinez, Kristin L., Maschmann, Marc, Masci, Gregory L., Masetti, Margaret E., Maszkiewicz, Michael, Matthews, Gary, Matuskey, Jacob E., McBrayer, Glen A., McCarthy, Donald W., McCaughrean, Mark J., McClare, Leslie A., McClare, Michael D., McCloskey, John C., McClurg, Taylore D., McCoy, Martin, McElwain, Michael W., McGregor, Roy D., McGuffey, Douglas B., McKay, Andrew G., McKenzie, William K., McLean, Brian, McMaster, Matthew, McNeil, Warren, De Meester, Wim, Mehalick, Kimberly L., Meixner, Margaret, Meléndez, Marcio, Menzel, Michael P., Menzel, Michael T., Merz, Matthew, Mesterharm, David D., Meyer, Michael R., Meyett, Michele L., Meza, Luis E., Midwinter, Calvin, Milam, Stefanie N., Miller, Jay Todd, Miller, William C., Miskey, Cherie L., Misselt, Karl, Mitchell, Eileen P., Mohan, Martin, Montoya, Emily E., Moran, Michael J., Morishita, Takahiro, Moro-Martín, Amaya, Morrison, Debra L., Morrison, Jane, Morse, Ernie C., Moschos, Michael, Moseley, S. H., Mosier, Gary E., Mosner, Peter, Mountain, Matt, Muckenthaler, Jason S., Mueller, Donald G., Mueller, Migo, Muhiem, Daniella, Mühlmann, Prisca, Mullally, Susan Elizabeth, Mullen, Stephanie M., Munger, Alan J, Murphy, Jess, Murray, Katherine T., Muzerolle, James C., Mycroft, Matthew, Myers, Andrew, Myers, Carey R., Myers, Fred Richard R., Myers, Richard, Myrick, Kaila, Nagle IV, Adrian F., Nayak, Omnarayani, Naylor, Bret, Neff, Susan G., Nelan, Edmund P., Nella, John, Nguyen, Duy Tuong, Nguyen, Michael N., Nickson, Bryony, Nidhiry, John Joseph, Niedner, Malcolm B., Nieto-Santisteban, Maria, Nikolov, Nikolay K., Nishisaka, Mary Ann, Nota, Antonella, O'Mara, Robyn C., Oboryshko, Michael, O'Brien, Marcus B., Ochs, William R., Offenberg, Joel D., Ogle, Patrick Michael, Ohl, Raymond G., Olmsted, Joseph Hamden, Osborne, Shannon Barbara, O'Shaughnessy, Brian Patrick, Östlin, Göran, O'Sullivan, Brian, Otor, O. Justin, Ottens, Richard, Ouellette, Nathalie N. -Q., Outlaw, Daria J., Owens, Beverly A., Pacifici, Camilla, Page, James Christophe, Paranilam, James G., Park, Sang, Parrish, Keith A., Paschal, Laura, Patapis, Polychronis, Patel, Jignasha, Patrick, Keith, Pattishall Jr., Robert A., Paul, Douglas William, Paul, Shirley J., Pauly, Tyler Andrew, Pavlovsky, Cheryl M., Peña-Guerrero, Maria, Pedder, Andrew H., Peek, Matthew Weldon, Pelham, Patricia A., Penanen, Konstantin, Perriello, Beth A., Perrin, Marshall D., Perrine, Richard F., Perrygo, Chuck, Peslier, Muriel, Petach, Michael, Peterson, Karla A., Pfarr, Tom, Pierson, James M., Pietraszkiewicz, Martin, Pilchen, Guy, Pipher, Judy L., Pirzkal, Norbert, Pitman, Joseph T., Player, Danielle M., Plesha, Rachel, Plitzke, Anja, Pohner, John A., Poletis, Karyn Konstantin, Pollizzi, Joseph A., Polster, Ethan, Pontius, James T., Pontoppidan, Klaus, Porges, Susana C., Potter, Gregg D., Prescott, Stephen, Proffitt, Charles R., Pueyo, Laurent, Neira, Irma Aracely Quispe, Radich, Armando, Rager, Reiko T., Rameau, Julien, Ramey, Deborah D., Alarcon, Rafael Ramos, Rampini, Riccardo, Rapp, Robert, Rashford, Robert A., Rauscher, Bernard J., Ravindranath, Swara, Rawle, Timothy, Rawlings, Tynika N., Ray, Tom, Regan, Michael W., Rehm, Brian, Rehm, Kenneth D., Reid, Neill, Reis, Carl A., Renk, Florian, Reoch, Tom B., Ressler, Michael, Rest, Armin W., Reynolds, Paul J., Richon, Joel G., Richon, Karen V., Ridgaway, Michael, Riedel, Adric Richard, Rieke, George H., Rieke, Marcia, Rifelli, Richard E., Rigby, Jane R., Riggs, Catherine S., Ringel, Nancy J., Ritchie, Christine E., Rix, Hans-Walter, Robberto, Massimo, Robinson, Michael S., Robinson, Orion, Rock, Frank W., Rodriguez, David R., del Pino, Bruno Rodríguez, Roellig, Thomas, Rohrbach, Scott O., Roman, Anthony J., Romelfanger, Frederick J., Romo Jr., Felipe P., Rosales, Jose J., Rose, Perry, Roteliuk, Anthony F., Roth, Marc N., Rothwell, Braden Quinn, Rouzaud, Sylvain, Rowe, Jason, Rowlands, Neil, Roy, Arpita, Royer, Pierre, Rui, Chunlei, Rumler, Peter, Rumpl, William, Russ, Melissa L., Ryan, Michael B., Ryan, Richard M., Saad, Karl, Sabata, Modhumita, Sabatino, Rick, Sabbi, Elena, Sabelhaus, Phillip A., Sabia, Stephen, Sahu, Kailash C., Saif, Babak N., Salvignol, Jean-Christophe, Samara-Ratna, Piyal, Samuelson, Bridget S., Sanders, Felicia A., Sappington, Bradley, Sargent, B. A., Sauer, Arne, Savadkin, Bruce J., Sawicki, Marcin, Schappell, Tina M., Scheffer, Caroline, Scheithauer, Silvia, Scherer, Ron, Schiff, Conrad, Schlawin, Everett, Schmeitzky, Olivier, Schmitz, Tyler S., Schmude, Donald J., Schneider, Analyn, Schreiber, Jürgen, Schroeven-Deceuninck, Hilde, Schultz, John J., Schwab, Ryan, Schwartz, Curtis H., Scoccimarro, Dario, Scott, John F., Scott, Michelle B., Seaton, Bonita L., Seely, Bruce S., Seery, Bernard, Seidleck, Mark, Sembach, Kenneth, Shanahan, Clare Elizabeth, Shaughnessy, Bryan, Shaw, Richard A., Shay, Christopher Michael, Sheehan, Even, Sheth, Kartik, Shih, Hsin-Yi, Shivaei, Irene, Siegel, Noah, Sienkiewicz, Matthew G., Simmons, Debra D., Simon, Bernard P., Sirianni, Marco, Sivaramakrishnan, Anand, Slade, Jeffrey E., Sloan, G. C., Slocum, Christine E., Slowinski, Steven E., Smith, Corbett T., Smith, Eric P., Smith, Erin C., Smith, Koby, Smith, Robert, Smith, Stephanie J., Smolik, John L., Soderblom, David R., Sohn, Sangmo Tony, Sokol, Jeff, Sonneborn, George, Sontag, Christopher D., Sooy, Peter R., Soummer, Remi, Southwood, Dana M., Spain, Kay, Sparmo, Joseph, Speer, David T., Spencer, Richard, Sprofera, Joseph D., Stallcup, Scott S., Stanley, Marcia K., Stansberry, John A., Stark, Christopher C., Starr, Carl W., Stassi, Diane Y., Steck, Jane A., Steeley, Christine D., Stephens, Matthew A., Stephenson, Ralph J., Stewart, Alphonso C., Stiavelli, Massimo, Stockman Jr., Hervey, Strada, Paolo, Straughn, Amber N., Streetman, Scott, Strickland, David Kendal, Strobele, Jingping F., Stuhlinger, Martin, Stys, Jeffrey Edward, Such, Miguel, Sukhatme, Kalyani, Sullivan, Joseph F., Sullivan, Pamela C., Sumner, Sandra M., Sun, Fengwu, Sunnquist, Benjamin Dale, Swade, Daryl Allen, Swam, Michael S., Swenton, Diane F., Swoish, Robby A., Litten, Oi In Tam, Tamas, Laszlo, Tao, Andrew, Taylor, David K., Taylor, Joanna M., Plate, Maurice te, Van Tea, Mason, Teague, Kelly K., Telfer, Randal C., Temim, Tea, Texter, Scott C., Thatte, Deepashri G., Thompson, Christopher Lee, Thompson, Linda M., Thomson, Shaun R., Thronson, Harley, Tierney, C. M., Tikkanen, Tuomo, Tinnin, Lee, Tippet, William Thomas, Todd, Connor William, Tran, Hien D., Trauger, John, Trejo, Edwin Gregorio, Truong, Justin Hoang Vinh, Tsukamoto, Christine L., Tufail, Yasir, Tumlinson, Jason, Tustain, Samuel, Tyra, Harrison, Ubeda, Leonardo, Underwood, Kelli, Uzzo, Michael A., Vaclavik, Steven, Valenduc, Frida, Valenti, Jeff A., Van Campen, Julie, van de Wetering, Inge, Van Der Marel, Roeland P., van Haarlem, Remy, Vandenbussche, Bart, Vanterpool, Dona D., Vernoy, Michael R., Costas, Maria Begoña Vila, Volk, Kevin, Voorzaat, Piet, Voyton, Mark F., Vydra, Ekaterina, Waddy, Darryl J., Waelkens, Christoffel, Wahlgren, Glenn Michael, Walker Jr., Frederick E., Wander, Michel, Warfield, Christine K., Warner, Gerald, Wasiak, Francis C., Wasiak, Matthew F., Wehner, James, Weiler, Kevin R., Weilert, Mark, Weiss, Stanley B., Wells, Martyn, Welty, Alan D., Wheate, Lauren, Wheeler, Thomas P., White, Christy L., Whitehouse, Paul, Whiteleather, Jennifer Margaret, Whitman, William Russell, Williams, Christina C., Willmer, Christopher N. A., Willott, Chris J., Willoughby, Scott P., Wilson, Andrew, Wilson, Debra, Wilson, Donna V., Windhorst, Rogier, Wislowski, Emily Christine, Wolfe, David J., Wolfe, Michael A., Wolff, Schuyler, Wondel, Amancio, Woo, Cindy, Woods, Robert T., Worden, Elaine, Workman, William, Wright, Gillian S., Wu, Carl, Wu, Chi-Rai, Wun, Dakin D., Wymer, Kristen B., Yadetie, Thomas, Yan, Isabelle C., Yang, Keith C., Yates, Kayla L., Yeager, Christopher R., Yerger, Ethan John, Young, Erick T., Young, Gary, Yu, Gene, Yu, Susan, Zak, Dean S., Zeidler, Peter, Zepp, Robert, Zhou, Julia, Zincke, Christian A., Zonak, Stephanie, and Zondag, Elisabeth

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

Twenty-six years ago a small committee report, building on earlier studies, expounded a compelling and poetic vision for the future of astronomy, calling for an infrared-optimized space telescope with an aperture of at least $4m$. With the support of their governments in the US, Europe, and Canada, 20,000 people realized that vision as the $6.5m$ James Webb Space Telescope. A generation of astronomers will celebrate their accomplishments for the life of the mission, potentially as long as 20 years, and beyond. This report and the scientific discoveries that follow are extended thank-you notes to the 20,000 team members. The telescope is working perfectly, with much better image quality than expected. In this and accompanying papers, we give a brief history, describe the observatory, outline its objectives and current observing program, and discuss the inventions and people who made it possible. We cite detailed reports on the design and the measured performance on orbit., Comment: Accepted by PASP for the special issue on The James Webb Space Telescope Overview, 29 pages, 4 figures

Published
2023
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35. Bacterial Infections in End-Stage Liver Disease: Implications for Liver Transplantation

Author

Alberto Ferrarese, Marco Senzolo, Anna Maria Cattelan, Lolita Sasset, Sara Battistella, Alberto Zanetto, Giacomo Germani, Francesco Paolo Russo, Martina Gambato, Filippo Pelizzaro, Stefania Vio, Domenico Bassi, Umberto Cillo, and Patrizia Burra

Subjects
enterobacterales, sepsis, acute on chronic liver failure, Surgery, RD1-811
Abstract

Bacterial infections are a common complication in patients with decompensated liver cirrhosis. The complex landscape of cirrhosis, characterized by immune paralysis and an exhausted response to exogenous triggers, explains the higher prevalence of such infections, particularly in advanced disease stages. In clinical practice, the onset of a bacterial infection can lead to further deterioration of hepatic and extra-hepatic function, potentially resulting in acute decompensation or acute-on-chronic liver failure. This has significant clinical implications, particularly for patients awaiting a transplant. In this review, we will discuss the latest evidence on the diagnosis and therapy of bacterial infections in patients with decompensated cirrhosis. Additionally, we will analyze the impact of bacterial infections in the context of liver transplantation, discussing debated topics such as the timing of transplantation in patients with infections, potential implications for prioritization, effects on post-operative recovery, grafts, and patient survival.

Published
2024
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36. AGN STORM 2: II. Ultraviolet Observations of Mrk817 with the Cosmic Origins Spectrograph on the Hubble Space Telescope

Author

Homayouni, Y., De Rosa, Gisella, Plesha, Rachel, Kriss, Gerard A., Barth, Aaron J., Cackett, Edward M., Horne, Keith, Kara, Erin A., Landt, Hermine, Arav, Nahum, Boizelle, Benjamin D., Bentz, Misty C., Brink, Thomas G., Brotherton, Michael S., Chelouche, Doron, Bonta, Elena Dalla, Dehghanian, Maryam, Du, Pu, Ferland, Gary J., Ferrarese, Laura, Fian, Carina, Filippenko, Alexei V., Fischer, Travis, Foley, Ryan J., Gelbord, Jonathan, Goad, Michael R., Buitrago, Diego H. Gonzalez, Gorjian, Varoujan, Grier, Catherine J., Hall, Patrick B., Santisteban, Juan V. Hernandez, Hu, Chen, Ilic, Dragana, Joner, Michael D., Kaastra, Jelle, Kaspi, Shai, Kochanek, Christopher S., Korista, Kirk T., Kovacevic, Andjelka B., Kynoch, Daniel, Li, Yan-Rong, McHardy, Ian M., McLane, Jacob N., Mehdipour, Missagh, Miller, Jake A., Mitchell, Jake, Montano, John, Netzer, Hagai, Panagiotou, Christos, Partington, Ethan, Pogge, Richard W., Popovic, Luka C., Proga, Daniel, Rogantini, Daniele, Storchi-Bergmann, Thaisa, Sanmartim, David, Siebert, Matthew R., Treu, Tommaso, Vestergaard, Marianne, Wang, Jian-Min, Ward, Martin J., Waters, Tim, Williams, Peter R., Zaidouni, Fatima, and Zu, Ying

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

We present reverberation mapping measurements for the prominent ultraviolet broad emission lines of the active galactic nucleus Mrk817 using 165 spectra obtained with the Cosmic Origins Spectrograph on the Hubble Space Telescope. Our ultraviolet observations are accompanied by X-ray, optical, and near-infrared observations as part of the AGN Space Telescope and Optical Reverberation Mapping Program 2 (AGN STORM 2). Using the cross-correlation lag analysis method, we find significant correlated variations in the continuum and emission-line light curves. We measure rest-frame delayed responses between the far-ultraviolet continuum at 1180 A and Ly$\alpha$ $\lambda1215$ A ($10.4_{-1.4}^{+1.6}$ days), N V $\lambda1240$ A ($15.5_{-4.8}^{+1.0}$days), SiIV + OIV] $\lambda1397$ A ($8.2_{-1.4}^{+1.4}$ days), CIV $\lambda1549$ A ($11.8_{-2.8}^{+3.0}$ days), and HeII $\lambda1640$ A ($9.0_{-1.9}^{+4.5}$ days) using segments of the emission-line profile that are unaffected by absorption and blending, which results in sampling different velocity ranges for each line. However, we find that the emission-line responses to continuum variations are more complex than a simple smoothed, shifted, and scaled version of the continuum light curve. We also measure velocity-resolved lags for the Ly$\alpha$, and CIV emission lines. The lag profile in the blue wing of Ly$\alpha$ is consistent with virial motion, with longer lags dominating at lower velocities, and shorter lags at higher velocities. The CIV lag profile shows the signature of a thick rotating disk, with the shortest lags in the wings, local peaks at $\pm$ 1500 $\rm km\,s^{-1}$, and a local minimum at line center. The other emission lines are dominated by broad absorption lines and blending with adjacent emission lines. These require detailed models, and will be presented in future work., Comment: Submitted to ApJ. 25 pages, 8 figures, and 6 tables

Published
2023
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37. A Fully Edible Transistor Based on a Toothpaste Pigment

Author

Elena Feltri, Pierluigi Mondelli, Bojan Petrović, Fabrizio Mario Ferrarese, Alina Sharova, Goran Stojanović, Alessandro Luzio, and Mario Caironi

Subjects
copper phthalocyanine, edible electronics, edible semiconductor, EGOFET, organic transistor, Science
Abstract

Abstract Edible electronics is emerging in recent years motivated by a diverse number of healthcare applications, where sensors can be safely ingested without the need for any medical supervision. However, the current lack of stable and well‐performing edible semiconductors needs to be addressed to reach technological maturity and allow the surge of a new generation of edible circuits. In the quest for good‐performing edible semiconductors, this study has explored the possibility of considering materials that are not regulated for intentional ingestion, yet are daily swallowed with no adverse reactions, such as pigments contained in toothpaste. This work first elaborates on the basis of inadvertent ingestion data to estimate the quantity of daily ingested Copper(II) Phthalocyanine (CuPc), a whitening pigment and well‐known organic semiconductor. Subsequently, CuPc is employed in the first demonstration of fully edible electrolyte‐gated transistors operating at low voltage (

Published
2024
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38. A holistic evaluation of patients with chronic Hepatitis D virus (HDV) infection enrolled in the Italian PITER-B and delta cohort

Author

Loreta A. Kondili, Giuseppina Brancaccio, Maria Elena Tosti, Barbara Coco, Maria Giovanna Quaranta, Vincenzo Messina, Alessia Ciancio, Filomena Morisco, Valentina Cossiga, Ernesto Claar, Valerio Rosato, Marianna Ciarallo, Irene Cacciola, Francesca Romana Ponziani, Lucia Cerrito, Roberta Coppola, Francesco Longobardi, Elisa Biliotti, Alessia Rianda, Francesco Barbaro, Nicola Coppola, Maria Stanzione, Francesco Barchiesi, Stefano Fagiuoli, Mauro Viganò, Marco Massari, Francesco Paolo Russo, Alberto Ferrarese, Diletta Laccabue, Vito Di Marco, Pierluigi Blanc, Aldo Marrone, Giulia Morsica, Alessandro Federico, Donatella Ieluzzi, Alba Rocco, Francesco Giuseppe Foschi, Alessandro Soria, Ivana Maida, Luchino Chessa, Michele Milella, Elena Rosselli Del Turco, Salvatore Madonia, Liliana Chemello, Ivan Gentile, Pierluigi Toniutto, Matteo Bassetti, Lorenzo Surace, Leonardo Baiocchi, Adriano Pellicelli, Adriano De Santis, Massimo Puoti, Elisabetta Degasperi, Grazia Anna Niro, Anna Linda Zignego, Antonio Craxi, Giovanni Raimondo, Teresa Antonia Santantonio, Maurizia Rossana Brunetto, Giovanni Battista Gaeta, Alessio Aghemo, Chiara Baiguera, Pier Maria Battezzati, Sara Battistella, Maria Grazia Bavetta, Costanza Bertoni, Carolina Boni, Paola Brambilla, Antonella Bray, Federica Briano, Enrico Carmenini, Francesco Castelli, Luisa Cavalletto, Federica Cerini, Luciana Chidichimo, Elisa Colella, Giuliana Cologni, Silvia Como, Romina Corsini, Chiara Costa, Rosa Cotugno, Silvia Cretella, Fernando De Angelis, Pasqualina De Leo, Giovanni Di Perri, Elisabetta Falbo, Luigina Ferrigno, Ezio Fornasiere, Daniela Francisci, Pietro Gatti, Pietro Lampertico, Ilaria Lenci, Anna Licata, Alfredo Marzano, Antonio Mastroianni, Cesare Mazzaro, Monica Monti, Gerardo Nardone, Laura Ambra Nicolini, Nicola Passigato, Maria Bruna Pasticci, Piera Pierotti, Biagio Pinchera, Teresa Pollicino, Carmen Porcu, Giulia Quartini, Gabriele Rancatore, Mario Romeo, Maria Grazia Rumi, Annalisa Saracino, Ornella Schioppa, Ilaria Serio, Roberta Soffredini, Xhimi Tata, Marco Tizzani, Matteo Tonnini, Carlo Torti, Daniela Valenti, Serena Zaltron, and Alessia Zoncada

Subjects
Cohort, IFN treatment, Comorbidities, Infectious and parasitic diseases, RC109-216
Abstract

Background and Aims: We aimed to characterize the epidemiologic and comorbidities profiles of patients with chronic Hepatitis D (CHD) followed in clinical practice in Italy and explored their interferon (IFN) eligibility. Methods: This was a cross-sectional study of the PITER cohort consisting of consecutive HBsAg-positive patients from 59 centers over the period 2019-2023. Multivariable analysis was performed by logistic regression model. Results: Of 5492 HBsAg-positive enrolled patients, 4152 (75.6%) were screened for HDV, 422 (10.2%) were anti-HDV positive. Compared with HBsAg mono-infected, anti-HDV positive patients were more often younger, non-Italians, with a history of drug use, had elevated alanine transaminase (ALT), cirrhosis, or hepatocellular carcinoma (HCC). Compared with Italians, anti-HDV positive non-Italians were younger (42.2% age ≤ 40 years vs. 2.1%; P < 0.001), more often females (males 43.0% vs. 68.6%; P < 0.001) with less frequent cirrhosis and HCC. HDV-RNA was detected in 63.2% of anti-HDV-positive patients, who were more likely to have elevated ALT, cirrhosis, and HCC. Extrahepatic comorbidities were present in 47.4% of anti-HDV positive patients and could affect the eligibility of IFN-containing therapies in at least 53.0% of patients in care. Conclusions: CHD affects young, foreign-born patients and older Italians, of whom two-thirds had cirrhosis or HCC. Comorbidities were frequent in both Italians and non-Italians and impacted eligibility for IFN.

Published
2024
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39. A Virgo Environmental Survey Tracing Ionised Gas Emission (VESTIGE).XIV. The main sequence relation in a rich environment down to M_star ~ 10^6 Mo

Author

Boselli, A., Fossati, M., Roediger, J., Boquien, M., Fumagalli, M., Balogh, M., Boissier, S., Braine, J., Ciesla, L., Côté, P., Cuillandre, J. C., Ferrarese, L., Gavazzi, G., Gwyn, S., Junais, Hensler, G., Longobardi, A., and Sun, M.

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

Using a compilation of Halpha fluxes for 384 star forming galaxies detected during the VESTIGE survey, we study several important scaling relations for a complete sample of galaxies in a rich environment. The extraordinary sensitivity of the data allows us to sample the whole dynamic range of the Halpha luminosity function, from massive (M*~10^11 Mo) to dwarf systems (M*~10^6 Mo). This extends previous works to a dynamic range in stellar mass and star formation rate (10^-4

Published
2022
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41. Two-year cardio-pulmonary follow-up after severe COVID-19: a prospective study

Author

Faverio, Paola, Paciocco, Giuseppe, Tassistro, Elena, Rebora, Paola, Rossi, Emanuela, Monzani, Anna, Tundo, Marta, Milano, Chiara, Messa, Martina, Marocchi, Raffaele, Pesci, Alberto, Foti, Giuseppe, Squillace, Nicola, Cogliandro, Viola, Lettino, Maddalena, Strepparava, Maria Grazia, Bellelli, Giuseppe, Ferrarese, Carlo, Valsecchi, Maria Grazia, Bonfanti, Paolo, and Luppi, Fabrizio

Published
2024
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42. A Virgo Environmental Survey Tracing Ionised Gas Emission (VESTIGE).XIII. The role of ram-pressure stripping in transforming the diffuse and ultra-diffuse galaxies in the Virgo cluster

Author

Junais, Boissier, S., Boselli, A., Ferrarese, L., Côté, P., Gwyn, S., Roediger, J., Lim, S., Peng, E. W., Cuillandre, J. -C., Longobardi, A., Fossati, M., Hensler, G., Koda, J., Bautista, J., Boquien, M., Małek, K., Amram, P., and Roehlly, Y.

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

Low-surface-brightness galaxies (LSBs) contribute to a significant fraction of all the galaxies in the Universe. Ultra-diffuse galaxies (UDGs) form a subclass of LSBs that has attracted a lot of attention in recent years (although its definition may vary between studies). Although UDGs are found in large numbers in galaxy clusters, groups, and in the field, their formation and evolution are still very much debated. Using a comprehensive set of multiwavelength data from the NGVS (optical), VESTIGE (H$\alpha$ narrowband), and GUViCS (UV) surveys, we studied a sample of 64 diffuse galaxies and UDGs in the Virgo cluster to investigate their formation history. We analyzed the photometric colors and surface-brightness profiles of these galaxies and then compared them to models of galaxy evolution, including ram-pressure stripping (RPS) events to infer any possible strong interactions with the hot cluster gas in the past. While our sample consists mainly of red LSBs, which is typical in cluster environments, we found evidence of a color variation with the cluster-centric distance. Blue, HI-bearing, star-forming diffuse galaxies are found at larger distances from the cluster center than the rest of the sample. The comparison of our models with multifrequency observations suggests that most of the galaxies of the sample might have undergone a strong RPS event in their lifetime, on average 1.6 Gyr ago (with a large dispersion, and RPS still ongoing for some of them). This process resulted in the transformation of initially gas-rich diffuse blue galaxies into gas-poor and red ones that form the dominant population now, the more extreme UDGs having undergone the process in a more distant past on average. The RPS in dense environments could be one of the major mechanisms for the formation of the large number of quiescent UDGs we observe in galaxy clusters., Comment: 57 pages, 14 Figures, accepted for publication in A&A

Published
2022
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43. The Spectroscopy and H-band Imaging of Virgo cluster galaxies (SHIVir) Survey: Data Catalogue and Kinematic Profiles

Author

Ouellette, Nathalie N. -Q., Courteau, Stéphane, Holtzman, Jon A., McDonald, Michael, Cappellari, Michele, Roediger, Joel C., Côté, Patrick, Dalcanton, Julianne J., Bontà, Elena Dalla, Ferrarese, Laura, Tully, R. Brent, Stone, Connor, and Peng, Eric W.

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

The ``Spectroscopy and H-band Imaging of Virgo cluster galaxies'' (SHIVir) survey is an optical and near-infrared survey which combines SDSS photometry, deep H-band photometry, and long-slit optical spectroscopy for 190 Virgo cluster galaxies (VCGs) covering all morphological types over the stellar mass range log (M_*/M_Sun) = 7.8-11.5$. We present the spectroscopic sample selection, data reduction, and analysis for this SHIVir sample. We have used and optimised the \texttt{pPXF} routine to extract stellar kinematics from our data. Ultimately, resolved kinematic profiles (rotation curves and velocity dispersion profiles) are available for 133 SHIVir galaxies. A comprehensive database of photometric and kinematic parameters for the SHIVir sample is presented with: grizH magnitudes, effective surface brightnesses, effective and isophotal radii, rotational velocities, velocity dispersions, and stellar and dynamical masses. Parameter distributions highlight some bimodal distributions and possible sample biases. A qualitative study of resolved extended velocity dispersion profiles suggests a link between the so-called ``sigma-drop'' kinematic profile and the presence of rings in lenticular S0 galaxies. Rising dispersion profiles are linked to early-type spirals or dwarf ellipticals for which a rotational component is significant, whereas peaked profiles are tied to featureless giant ellipticals., Comment: 21 pages, 16 figures, accepted for publication in MNRAS (doi: 10.1093/mnras/stac1347). Supplemental material available at https://www.queensu.ca/academia/courteau/links

Published
2022
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44. Soybean and maize differentially metabolize deuterated ferulic and sinapic acids before polymerizing them into the root cell wall

Author

Aline Marengoni Almeida, Diany Lucy Silveira dos Reis, Eduardo Jorge Pilau, Rogério Barbosa de Lima, Rodrigo Polimeni Constantin, Rogério Marchiosi, Osvaldo Ferrarese-Filho, and Wanderley Dantas dos Santos

Subjects
Allelopathy, Hydroxycinnamic acids, Lignin, Phenylpropanoid pathway, Phenolic compounds, Secondary metabolism, Botany, QK1-989
Abstract

Hydroxycinnamates induce lignification in young plants, leading to the overproduction of lignin as a defense mechanism. Phenylpropanoids-containing oligosaccharides are thought to be a signal of pathogen attack on the cell wall polysaccharides. However, it is unclear if hydroxycinnamates induce lignification by acting solely as stress elicitors or feeding the phenylpropanoid pathway as lignin precursors. To examine this hypothesis, we added 1 mM deuterated ferulic acid (FA) or sinapic acid (SA) to the nutrient solution in which we cultivated soybean or maize plantlets. After 24 h, we assessed the biometric parameters and the contents of ester-linked FA and SA, total lignin, monolignol ratio, and heavy monolignols. FA treatment increased the content of ester-linked FA, syringyl, and guaiacyl monomers measured by nitrobenzene oxidation, lignin content, and reduced root growth in both soybean and maize plants. p-Coumaric acid content ester-linked to the cell wall increased in soybean but decreased in maize after treatment with FA. Treatment with SA also induced lignification in soybean but not in maize. SA increased S-lignin and sinapoyl esters content in the cell wall polymers in both soybean and maize. Residues of deuterated hydroxycinnamates were detected in the lignin of both plants in both treatments. The assay demonstrated that exogenously applied SA and FA were metabolized through the phenylpropanoid pathway. Furthermore, they were, at least partially, exported to the apoplast, where they were ester-linked to cell wall polymers. This suggests hydroxycinnamic acids are metabolized differently by plants with different types of cell walls.

Published
2024
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45. Ultra-High-Energy Cosmic Rays: The Intersection of the Cosmic and Energy Frontiers

Author

Coleman, A., Eser, J., Mayotte, E., Sarazin, F., Schröder, F. G., Soldin, D., Venters, T. M., Aloisio, R., Alvarez-Muñiz, J., Batista, R. Alves, Bergman, D., Bertaina, M., Caccianiga, L., Deligny, O., Dembinski, H. P., Denton, P. B., di Matteo, A., Globus, N., Glombitza, J., Golup, G., Haungs, A., Hörandel, J. R., Jaffe, T. R., Kelley, J. L., Krizmanic, J. F., Lu, L., Matthews, J. N., Mariş, I., Mussa, R., Oikonomou, F., Pierog, T., Santos, E., Tinyakov, P., Tsunesada, Y., Unger, M., Yushkov, A., Albrow, M. G., Anchordoqui, L. A., Andeen, K., Arnone, E., Barghini, D., Bechtol, E., Bellido, J. A., Casolino, M., Castellina, A., Cazon, L., Conceição, R., Cremonini, R., Dujmovic, H., Engel, R., Farrar, G., Fenu, F., Ferrarese, S., Fujii, T., Gardiol, D., Gritsevich, M., Homola, P., Huege, T., Kampert, K. -H., Kang, D., Kido, E., Klimov, P., Kotera, K., Kozelov, B., Leszczyńska, A., Madsen, J., Marcelli, L., Marisaldi, M., Martineau-Huynh, O., Mayotte, S., Mulrey, K., Murase, K., Muzio, M. S., Ogio, S., Olinto, A. V., Onel, Y., Paul, T., Piotrowski, L., Plum, M., Pont, B., Reininghaus, M., Riedel, B., Riehn, F., Roth, M., Sako, T., Schlüter, F., Shoemaker, D., Sidhu, J., Sidelnik, I., Timmermans, C., Tkachenko, O., Veberič, D., Verpoest, S., Verzi, V., Vícha, J., Winn, D., Zas, E., and Zotov, M.

Subjects
Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Instrumentation and Methods for Astrophysics, High Energy Physics - Experiment
Abstract

The present white paper is submitted as part of the "Snowmass" process to help inform the long-term plans of the United States Department of Energy and the National Science Foundation for high-energy physics. It summarizes the science questions driving the Ultra-High-Energy Cosmic-Ray (UHECR) community and provides recommendations on the strategy to answer them in the next two decades., Comment: Prepared as a solicited white paper for the 2021 Snowmass process. To be published in the Journal of High Energy Astrophysics. v2: fixed typos in author list. v3: included all community feedback received by July 1st 2022 and added the list of endorsers. v4 is the post-reviewer preprint accepted to Astroparticle Physics vol. 149

Published
2022
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46. The Next Generation Virgo Cluster Survey. XXXIII. Stellar Population Gradients in the Virgo Cluster Core Globular Cluster System

Author

Ko, Youkyung, Peng, Eric W., Côté, Patrick, Ferrarese, Laura, Liu, Chengze, Longobardi, Alessia, Lançon, Ariane, Muñoz, Roberto P., Puzia, Thomas H., Alamo-Martínez, Karla A., Sales, Laura V., Ramos-Almendares, Felipe, Abadi, Mario G., Lee, Myung Gyoon, Hwang, Ho Seong, Caldwell, Nelson, Blakeslee, John P., Boselli, Alessandro, Cuillandre, Jean-Charles, Duc, Pierre-Alain, Eyheramendy, Susana, Guhathakurta, Puragra, Gwyn, Stephen, Jordán, Andrés, Lim, Sungsoon, Sánchez-Janssen, Rubén, and Toloba, Elisa

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

We present a study of the stellar populations of globular clusters (GCs) in the Virgo Cluster core with a homogeneous spectroscopic catalog of 692 GCs within a major axis distance $R_{\rm maj} = $ 840 kpc from M87. We investigate radial and azimuthal variations in the mean age, total metallicity, [Fe/H], and $\alpha$-element abundance, of blue (metal-poor) and red (metal-rich) GCs using their co-added spectra. We find that the blue GCs have a steep radial gradient in [Z/H] within $R_{\rm maj} =$ 165 kpc, with roughly equal contributions from [Fe/H] and [$\alpha$/Fe], and flat gradients beyond. By contrast, the red GCs show a much shallower gradient in [Z/H], which is entirely driven by [Fe/H]. We use GC-tagged Illustris simulations to demonstrate an accretion scenario where more massive satellites (with more metal- and $\alpha$-rich GCs) sink further into the central galaxy than less massive ones, and where the gradient flattening occurs because of the low GC occupation fraction of low-mass dwarfs disrupted at larger distances. The dense environment around M87 may also cause the steep [$\alpha$/Fe] gradient of the blue GCs, mirroring what is seen in the dwarf galaxy population. The progenitors of red GCs have a narrower mass range than those of blue GCs, which makes their gradients shallower. We also explore spatial inhomogeneity in GC abundances, finding that the red GCs to the northwest of M87 are slightly more metal-rich. Future observations of GC stellar population gradients will be useful diagnostics of halo merger histories., Comment: 22 pages, 8 figures, 4 tables, accepted for publication in ApJ

Published
2022
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47. VOC emissions from Euro 6 vehicles

Author

Christian Ferrarese, Jacopo Franzetti, Tommaso Selleri, and Ricardo Suarez-Bertoa

Subjects
Volatile organic compounds, Pollutants emissions, Laboratory vehicle testing, Euro6d, Euro6d-TEMP, FTIR, Environmental sciences, GE1-350, Environmental law, K3581-3598
Abstract

Abstract Background Air pollution is a major health concern in worldwide. Non-methane volatile organic compounds (NMVOCs) are precursors of secondary air pollutants, with road transport being responsible of ~ 90% for the EU-27’s NMVOCs transport emissions in 2021. A series of VOC emissions from 17 modern gasoline, Diesel and Plug-in hybrid (PHEV) vehicles were investigated under various driving conditions and temperatures. All tested vehicles meet the latest European emission standard (Euro 6d and Euro 6d-TEMP). The different VOC species were measured with a Fourier-Transform Infrared Analyzer (FTIR). Results Diesel vehicles presented the lowest VOC emissions, while PHEVs operating in charge sustaining mode, with a depleted battery, exhibited very similar behavior to conventional gasoline. Among the VOCs, C5 compounds were the primary contributors to total NMVOCs over WLTC at 23 °C for gasoline and PHEV vehicles. A proportional increase in VOC emissions at colder temperatures, affecting all the studied species, was observed. Significant increases were observed for Aromatics, with an important contribution of

Published
2024
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48. Corticosteroid treatment for acute hydrocephalus in neurosarcoidosis: a case report

Author

Edoardo Dalmato Schilke, Giulia Remoli, Claudia Cutellé, Claudia Balducci, Diletta Cereda, Maria Letizia Fusco, Lucio Tremolizzo, Carlo Ferrarese, Ildebrando Appollonio, and Maura Frigo

Subjects
Neuroimmunology, Neurosarcoidosis, Obstructive hydrocephalus, Neurosurgery in sarcoidosis, Medicine
Abstract

Abstract Background Neurosarcoidosis occurs symptomatically in 5–10% of patients with sarcoidosis, and hydrocephalus is a rare complication of neurosarcoidosis, with either acute or subacute onset and presenting symptoms related to increased intracranial pressure. It represents a potentially fatal manifestation with a mortality rate of 22% (increased to 75% in case of coexistence of seizures) that requires a prompt initiation of treatment. High-dose intravenous corticosteroid treatment and neurosurgical treatment must be considered in all cases of neurosarcoidosis hydrocephalus. Case presentation Here we present a case of hydrocephalus in neurosarcoidosis, complicated by generalized seizures, in a 29-year-old Caucasian male patient treated with medical treatment only, with optimal response. Conclusion Since neurosurgery treatment can lead to severe complications, this case report underlines the possibility to undergo only medical treatment in selected cases. Further studies are needed to stratify patients and better identify those eligible for only medical approach.

Published
2024
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49. ACOD1 deficiency offers protection in a mouse model of diet-induced obesity by maintaining a healthy gut microbiota

Author

Tanja Eberhart, Federico Uchenna Stanley, Luisa Ricci, Tiziana Chirico, Roberto Ferrarese, Sofia Sisti, Alessandra Scagliola, Andreina Baj, Sylvia Badurek, Andreas Sommer, Rachel Culp-Hill, Monika Dzieciatkowska, Engy Shokry, David Sumpton, Angelo D’Alessandro, Nicola Clementi, Nicasio Mancini, and Simone Cardaci

Subjects
Cytology, QH573-671
Abstract

Abstract Aconitate decarboxylase 1 (ACOD1) is the enzyme synthesizing itaconate, an immuno-regulatory metabolite tuning host-pathogen interactions. Such functions are achieved by affecting metabolic pathways regulating inflammation and microbe survival. However, at the whole-body level, metabolic roles of itaconate remain largely unresolved. By using multiomics-integrated approaches, here we show that ACOD1 responds to high-fat diet consumption in mice by promoting gut microbiota alterations supporting metabolic disease. Genetic disruption of itaconate biosynthesis protects mice against obesity, alterations in glucose homeostasis and liver metabolic dysfunctions by decreasing meta-inflammatory responses to dietary lipid overload. Mechanistically, fecal metagenomics and microbiota transplantation experiments demonstrate such effects are dependent on an amelioration of the intestinal ecosystem composition, skewed by high-fat diet feeding towards obesogenic phenotype. In particular, unbiased fecal microbiota profiling and axenic culture experiments point towards a primary role for itaconate in inhibiting growth of Bacteroidaceae and Bacteroides, family and genus of Bacteroidetes phylum, the major gut microbial taxon associated with metabolic health. Specularly to the effects imposed by Acod1 deficiency on fecal microbiota, oral itaconate consumption enhances diet-induced gut dysbiosis and associated obesogenic responses in mice. Unveiling an unrecognized role of itaconate, either endogenously produced or exogenously administered, in supporting microbiota alterations underlying diet-induced obesity in mice, our study points ACOD1 as a target against inflammatory consequences of overnutrition.

Published
2024
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50. Neuropathological hints from CSF and serum biomarkers in corticobasal syndrome (CBS): a systematic review

Author

Giulia Remoli, Edoardo Dalmato Schilke, Andrea Magi, Antonio Ancidoni, Giulia Negro, Fulvio Da Re, Maura Frigo, Martina Giordano, Nicola Vanacore, Marco Canevelli, Carlo Ferrarese, Lucio Tremolizzo, and Ildebrando Appollonio

Subjects
Corticobasal syndrome, Fluid biomarkers, CBS biomarkers, CBS neuropathology, Dementia biomarkers, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429
Abstract

Abstract Corticobasal syndrome (CBS) is a clinical syndrome determined by various underlying neurodegenerative disorders requiring a pathological assessment for a definitive diagnosis. A literature review was performed following the methodology described in the Cochrane Handbook for Systematic Reviews to investigate the additional value of traditional and cutting-edge cerebrospinal fluid (CSF) and serum/plasma biomarkers in profiling CBS. Four databases were screened applying predefined inclusion criteria: (1) recruiting patients with CBS; (2) analyzing CSF/plasma biomarkers in CBS. The review highlights the potential role of the association of fluid biomarkers in diagnostic workup of CBS, since they may contribute to a more accurate diagnosis and patient selection for future disease-modifying agent; for example, future trial designs should consider baseline CSF Neurofilament Light Chains (NfL) or progranulin dosage to stratify treatment arms according to neuropathological substrates, and serum NfL dosage might be used to monitor the evolution of CBS. In this scenario, prospective cohort studies, starting with neurological examination and neuropsychological tests, should be considered to assess the correlations of clinical profiles and various biomarkers.

Published
2024
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