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7 results on '"Fernicola, Federica"'

2. Useful Clinical Criteria for Identifying Neonates with Congenital Cytomegalovirus Infection at Birth in the Context of an Expanded Targeted Screening Program.

Author

Poletti de Chaurand, Valeria, Scandella, Gaia, Zicoia, Marianna, Arienti, Francesca, Fernicola, Federica, Lanteri, Laura, Guglielmi, Diletta, Carli, Anna, Vasarri, Maria Viola, Iozzi, Lucia, Cavallero, Annalisa, Malandrin, Sergio Maria Ivano, Locatelli, Anna, Ventura, Maria Luisa, Sinelli, Mariateresa, and Ornaghi, Sara

Subjects
CYTOMEGALOVIRUS diseases, NEWBORN screening, SENSORINEURAL hearing loss, CONGENITAL disorders, MEDICAL screening
Abstract

Cytomegalovirus (CMV) is the leading infectious cause of brain defects and neurological dysfunctions, including sensorineural hearing loss (SNHL). Targeted screening in neonates failing the hearing screen is currently recommended in Italy according to national guidelines. However, SNHL may not be present at birth; also, congenital CMV (cCMV) may manifest with subtle signs other than SNHL. Therefore, the inclusion of additional criteria for cCMV screening appears clinically valuable. Starting January 2021, we have implemented expanded targeted cCMV screening at our center, with testing in case of maternal CMV infection during pregnancy, inadequate antenatal care, maternal HIV infection or immunosuppression, birthweight and/or head circumference < 10th centile, failed hearing screen, and prematurity. During the first three years of use of this program (2021–2023), 940 (12.3%) of 7651 live-born infants were tested. The most common indication was birthweight < 10th centile (n = 633, 67.3%). Eleven neonates were diagnosed as congenitally infected, for a prevalence of 1.17% (95%CI 0.48–1.86) on tested neonates and of 0.14% (95%CI 0.06–0.23) on live-born infants. None of the cCMV-infected newborns had a failed hearing screen as a testing indication. Implementation of an expanded cCMV screening program appears feasible and of clinical value. [ABSTRACT FROM AUTHOR]

Published
2024
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3. Letter to Editor: Asymptomatic CMV infection at birth following maternal infection, valacyclovir treatment, and a subsequent negative amniocentesis

Author

Fernicola, Federica, primary, Carli, Anna, additional, Arienti, Francesca, additional, Vasarri, Maria Viola, additional, Lanteri, Laura, additional, Scandella, Gaia, additional, De Chaurand, Valeria Poletti, additional, Zicoia, Marianna, additional, Iozzi, Lucia, additional, Ventura, Maria Luisa, additional, Sinelli, Mariateresa, additional, Locatelli, Anna, additional, and Ornaghi, Sara, additional

Published
2024
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4. 72 Increased risk of postpartum hemorrhage in women with resolved low placentation: a multicenter prospective study

Author

Sara, Ornaghi, primary, Arienti, Francesca, additional, Fernicola, Federica, additional, Abbamondi, Alessandra, additional, Giani, Sofia, additional, Colciago, Elisabetta, additional, Fumagalli, Simona, additional, Catalano, Anna, additional, Giuseppe, Meroni Mario, additional, Benedetti, Sara, additional, Bulfoni, Camilla, additional, Callegari, Clelia, additional, Sala, Andrea, additional, Barbolini, Edoardo, additional, Zangheri, Giulia, additional, Molin, Giulia Dal, additional, Vignali, Michele, additional, Pozzoni, Mirko, additional, Castoldi, Maria, additional, Candiani, Massimo, additional, Consonni, Sara, additional, Cetin, Irene, additional, Fabbri, Elisa, additional, Sala, Valentina, additional, and Locatelli, Anna, additional

Published
2024
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6. Fatal severe persistent pulmonary hypertension with lung microvasculature parietal hyperplasia in a neonate with congenital cytomegalovirus infection treated in-utero with valacyclovir: A case report

Author

Fernicola, Federica, Carli, Anna, Arienti, Francesca, Viola Vasarri, Maria, Lanteri, Laura, Scandella, Gaia, Poletti De Chaurand, Valeria, Zicoia, Marianna, Iozzi, Lucia, Gorla, Sonia, Luisa Ventura, Maria, Locatelli, Anna, Sinelli, Mariateresa, and Ornaghi, Sara

Published
2024
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7. Letter to Editor: Asymptomatic CMV infection at birth following maternal infection, valacyclovir treatment, and a subsequent negative amniocentesis.

Author

Fernicola F, Carli A, Arienti F, Vasarri MV, Lanteri L, Scandella G, De Chaurand VP, Zicoia M, Iozzi L, Ventura ML, Sinelli M, Locatelli A, and Ornaghi S

Subjects
Pregnancy, Infant, Newborn, Female, Humans, Valacyclovir therapeutic use, Amniocentesis, Antiviral Agents therapeutic use, Infectious Disease Transmission, Vertical prevention & control, Cytomegalovirus Infections diagnosis, Cytomegalovirus Infections drug therapy, Pregnancy Complications, Infectious diagnosis, Pregnancy Complications, Infectious drug therapy
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Published
2024
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