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11 results on '"Fernandes, Maria Gabriela O."'

1. Future perspective for the application of predictive biomarker testing in advanced stage non-small cell lung cancer

Author

de Jager, Vincent D., Timens, Wim, Bayle, Arnaud, Botling, Johan, Brcic, Luka, Büttner, Reinhard, Fernandes, Maria Gabriela O., Havel, Libor, Hochmair, Maximilian, Hofman, Paul, Janssens, Annelies, van Kempen, Léon, Kern, Izidor, Machado, José Carlos, Mohorčič, Katja, Popat, Sanjay, Ryška, Aleš, Wolf, Jürgen, Schuuring, Ed, and van der Wekken, Anthonie J.

Published
2024
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2. Developments in predictive biomarker testing and targeted therapy in advanced stage non-small cell lung cancer and their application across European countries

Author

de Jager, Vincent D., Timens, Wim, Bayle, Arnaud, Botling, Johan, Brcic, Luka, Büttner, Reinhard, Fernandes, Maria Gabriela O., Havel, Libor, Hochmair, Maximilian J., Hofman, Paul, Janssens, Annelies, Johansson, Mikael, van Kempen, Léon, Kern, Izidor, Lopez-Rios, Fernando, Lüchtenborg, Margreet, Machado, José Carlos, Mohorcic, Katja, Paz-Ares, Luis, Popat, Sanjay, Ryška, Aleš, Taniere, Phillipe, Wolf, Jürgen, Schuuring, Ed, and van der Wekken, Anthonie J.

Published
2024
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5. Liquid Biopsy for Disease Monitoring in Non-Small Cell Lung Cancer: The Link between Biology and the Clinic

Author

Fernandes, Maria Gabriela O., primary, Sousa, Catarina, additional, Pereira Reis, Joana, additional, Cruz-Martins, Natália, additional, Souto Moura, Conceição, additional, Guimarães, Susana, additional, Justino, Ana, additional, Pina, Maria João, additional, Magalhães, Adriana, additional, Queiroga, Henrique, additional, Marques, José Agostinho, additional, Machado, José Carlos, additional, Costa, José Luís, additional, and Hespanhol, Venceslau, additional

Published
2021
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7. Clinical Application of Next-Generation Sequencing of Plasma Cell-Free DNA for Genotyping Untreated Advanced Non-Small Cell Lung Cancer

Author

Fernandes, Maria Gabriela O., primary, Cruz-Martins, Natália, additional, Souto Moura, Conceição, additional, Guimarães, Susana, additional, Pereira Reis, Joana, additional, Justino, Ana, additional, Pina, Maria João, additional, Magalhães, Adriana, additional, Queiroga, Henrique, additional, Machado, José Carlos, additional, Hespanhol, Venceslau, additional, and Costa, José Luis, additional

Published
2021
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9. Resistance Profile of Osimertinib in Pre-treated Patients With EGFR T790M-Mutated Non-small Cell Lung Cancer

Author

Fernandes, Maria Gabriela O., primary, Sousa, Catarina, additional, Jacob, Maria, additional, Almeida, Leonor, additional, Santos, Vanessa, additional, Araújo, David, additional, Novais Bastos, Hélder, additional, Magalhães, Adriana, additional, Cirnes, Luís, additional, Moura, Conceição Souto, additional, Queiroga, Henrique, additional, Cruz-Martins, Natália, additional, and Hespanhol, Venceslau, additional

Published
2021
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10. Targeted Gene Next-Generation Sequencing Panel in Patients with Advanced Lung Adenocarcinoma: Paving the Way for Clinical Implementation

Author

Fernandes, Maria Gabriela O., primary, Jacob, Maria, additional, Martins, Natália, additional, Moura, Conceição Souto, additional, Guimarães, Susana, additional, Reis, Joana Pereira, additional, Justino, Ana, additional, Pina, Maria João, additional, Cirnes, Luís, additional, Sousa, Catarina, additional, Pinto, Josué, additional, Marques, José Agostinho, additional, Machado, José Carlos, additional, Hespanhol, Venceslau, additional, and Costa, José Luis, additional

Published
2019
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11. Endobronchial Ultrasound under Moderate Sedation versus General Anesthesia.

Author

Fernandes, Maria Gabriela O., Santos, Vanessa F., Martins, Natália, Sucena, Maria C., Passos, Madalena M., Marques, Maria Manuel, Magalhães, Adriana M., and Bugalho, António

Subjects
*ULTRASONIC imaging, *GENERAL anesthesia, *PATIENT satisfaction, *SYSTOLIC blood pressure, *HYPERTENSION
Abstract

Background: Different anesthetic protocols may influence endobronchial ultrasound-guided needle aspiration (EBUS-TBNA) outcomes, patient comfort, and even safety. In this study, two anesthesia techniques were assessed and compared for EBUS-TBNA. Methods: A prospective, multicenter study was carried out. Patients were allocated to Group 1 (general anesthesia with neuromuscular blockade and controlled ventilation) and Group 2 (intravenous sedation). EBUS-TBNA accuracy was the primary outcome. Safety, patient comfort and satisfaction, and operators' difficulties were defined as secondary outcomes. Results: Of the 115 patients enrolled (Group 1 = 59, Group 2 = 56), EBUS-TBNA was performed for hilar or mediastinal lesion diagnosis and lung cancer staging in, respectively, 77 (67%) and 38 (33%) patients. The numbers of lymph nodes stations (1.8 ± 1.0 vs. 1.7 ± 1.0, p = 0.472) and punctures per station (6.9 ± 3.1 vs. 6.0 ± 2.5, p = 0.084) were similar between groups. Adequate samples were obtained from 109 patients (97.3%) with similar diagnostic accuracy. Procedure duration was not significantly different (p = 0.348). Hemodynamic parameters and systolic and diastolic blood pressures were higher in Group 1 at the beginning and at the end of the procedure. Adverse events were equally distributed, and no significant differences were found regarding patient satisfaction and bronchoscopist/anesthesiologist difficulties. Conclusions: The type of anesthesia used did not influence EBUS-TBNA outcomes. EBUS-TBNA performed under sedation or general anesthesia did not affect the diagnostic yield, complication rate, and patients' comfort and satisfaction. [ABSTRACT FROM AUTHOR]

Published
2018
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