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For institutions of higher learning such as universities, the performance evaluation teaching staff is profoundly significant in the realization of the institution’s goals and objectives. It is also the social responsibility of these universities to ensure that the quality of education offered at their facilities is contextual and relevant to the graduates careers and the professions, which they undertake upon successful completion of these studies. As a nation committed to human capacity development, Angola recognizes and is continuously seek means to uphold exceptionally high standards of teacher performance as well as the general quality of services offered by the Angolan public universities. This chapter offers a summary of a comprehensive investigation dealing with 360° and competency evaluation for teaching staff at universities. The objective of this study was to develop and implement a system of evaluation of the teacher and lecturer performance at the José Eduardo dos Santos University of the Republic of Angola. The methodology used for evaluation the strengths and weaknesses of 122 teachers, the strengths and weaknesses in their individual performance; it also presents an improvement plan based on their competences to enhance individual teacher performance.

Recent advances in imaging studies and treatment approaches have greatly improved our knowledge about Giant Cell Arteritis (GCA). Previously thought of as a predominantly cranial disease, we now know that GCA is a systemic disease that may involve other medium and large vessel territories. Several imaging studies have shown that between 30 and 70% of patients with GCA present with large-vessel vasculitis. Moreover, a significant proportion of patients present large-vessel disease in the absence of cranial involvement. Extra-cranial disease also poses management challenges as these patients may have a more refractory-relapsing disease course and need additional therapies. Aortic dilation and aneurysms are well-described late complications of GCA involving the large artery territories. In this chapter, we discuss the clinical picture of extra-cranial involvement in GCA, focusing on improved diagnostic protocols and suitable treatment strategies.

Introdu����o: A reabilita����o card��aca tem-se revelado uma estrat��gia interventiva eficaz na promo����o da sa��de, maximizando a qualidade de vida (QV) do doente card��aco. Assim, este estudo tem por objetivo, avaliar os efeitos dos programas de reabilita����o na qualidade de vida da Pessoa com doen��a card��aca Objetivo: Avaliar os efeitos dos programas de reabilita����o na qualidade de vida da Pessoa com doen��a card��aca M��todos: Realizou-se uma revis��o integrativa da literatura, com pesquisa em plataformas eletr��nicas de bases de dados Scielo, Medline�� (via PubMed��),Cochrane Central Register of Controlled Trials, MEDLINE, Embase e CINAHL (EBSCO) e Reposit��rios Cient��ficos de Acesso Aberto em Portugal. Pesquisaram-se estudos publicados entre janeiro de 2015 a janeiro de 2021, respeitando-se os crit��rios de inclus��o e exclus��o previamente estabelecidos. O corpus darevis��o ficou constitu��do por 7 artigos. Resultados: Ficou demonstrado que os programas de reabilita����o card��aca melhoram globalmente a QV dos pacientes card��acos. Essas melhorias verificaram-se aos n��veis f��sico, emocional e social, bem como na gest��o dos fatores de risco cardiovascular. Existe evid��ncia de um benef��cio a curto prazo, atrav��s do treinof��sico e da aplica����o de exerc��cios adaptados na QV das pessoas. Conclus��o: Os programas de reabilita����o card��aca s��o efetivamente um recurso terap��utico com efic��cia transversalmente positiva na qualidade de vida dasPessoas com doen��a card��aca. Assim, torna-se imperativo que os Enfermeiros de reabilita����o desenvolvam programas de interven����o que proporcionem ganhosem sa��de e otimizem a qualidade de vida global dos Pacientes., Servir, N.�� 01 (2021): S��rie 2, n.�� 1

Catasetum �� sheyllae Krahl, Cantu��ria & J.B.F.Silva nothosp. nov. Type:��� BRAZIL. Par��: Aveiro, Mamuru River, epiphyte in Igap��, 3��14���20.41���S; 56��33���17.51���W, 11 m, 03 September 2020, J. B. F. da Silva 5488 (holotype INPA; Figs. 2, 3, 4, 5A���C). A natural hybrid between C. boyi and C. garnettianum with intermediate morphological features. It is characterized by the trilobed lip with two small triangular and erect calluses at the base of the lateral lobes, semi-oval and laciniate lateral lobes, an ovate-oblong median lobe with sparsely denticulate margins, and a small, dentiform, acute callus Epiphytic, cespitose plant. Rhizome short, inconspicuous. Pseudobulb fusiform, 6.8���14.5 �� 1.9���2.7 cm, 6���7-leaved, covered by leaf sheaths. Leaves oblanceolate, 28.6���51.2 �� 4.4���6.6 cm, membranous, plicate, prominently 5���7-veined, margin entire, base constricted, acute. Male inflorescence basal, 24.2���27.1 cm long, racemose, 11���14-flowers, first erect then arched due to the weight of the flowers; peduncle cylindrical, green, becoming purple towards apex; floral bract lanceolate, 0.9���1.1 �� 0.4���0.5 cm, concave, purplish-green, margin entire, apex acute. Female inflorescence basal, 18.2���22.5 cm long, racemose, 4���5-flowers; peduncle cylindrical, greenish; floral bract ovate, 1.0���1.2 �� 0.7���0.8 cm, concave, greenish, margin entire, apex acute. Male flowers with petals and sepals greenish with deep brownish spots and lip brownish outside and whitish inside, resupinate; pedicel 2.8���3.2 cm long, cylindrical, erect, purplish; dorsal sepal lanceolate, 3.0���3.3 �� 0.9���1.0 cm, concave, symmetrical, margin entire, acute; lateral sepals lanceolate, 3.0���3.3 �� 1.0��� 1.1 cm, concave, symmetrical, margin entire, involute, apex acute; petals elliptic, 2.6���2.8 �� 0.6���0.7 cm, symmetrical, margin entire, apex acute; lip trilobed, 1.3���1.4 �� 0.7���0.9 cm, with a saccate near the base, sac 0.4���0.5 cm deep, rounded, with two small calli at the base of the lateral lobes, calli 0.1���0.2 cm high, triangular, erect, acute; lateral lobes semi-ovate, 0.5���0.7 �� 0.5���0.6 cm, erect, margin laciniate, median lobe ovate-oblong, 0.6���0.8 �� 0.3���0.4 cm, margin sparsely dentate, apex acute with a small apical, tooth-shaped, acute, callus 0.1���0.2 cm high; column subtriangular, 1.9���2.1 cm long, fleshy, rostrate, contracted at base, brownish; rostellum 0.3���0.4 cm long, brownish; antennae 0.6���0.7 cm long, symmetrical, parallel to convergent, projected towards the bottom of the lip saccus; anther 0.8���0.9 cm long, purplish; anther cap 0.8���1.0 cm long, rostrate; viscidium 0.1���0.2 �� 0.1���0.15 cm long, whitish; stipe 0.2���0.3 �� 0.1 cm long, laminar, rolled, yellowish; pollinia 2, obovate, 0.3���0.4 �� 0.1���0.2 cm, hard, compressed, yellowish. Female flowers greenish-yellow with brownish spots on the sepals and petals, resupinate; pedicel 3.0��� 3.3 cm long, cylindrical, arched; sepals lanceolate, symmetrical, margin entire, apex acute, the dorsal sepal 2.0���2.2 �� 0.7���0.8 cm, the lateral sepals 2.1���2.3 �� 0.8���1.0 cm, with involute margins; petals elliptic, 2.0���2.2 �� 0.8���0.9 cm, symmetrical, apically acute; lip globular, 2.0���2.2 �� 1.9���2.1 cm, 1.0��� 1.2 cm deep, entire, striated inside, margin entire and thick, apex acute; column rounded, 2.8���3.0 cm long, fleshy, shortly rostrate, greenish; stigma 0.2���0.3 cm long, viscous. Fruit not seen. Etymology: ���The specific epithet is a tribute to the Brazilian pharmacist Sheylla Susan Moreira da Silva de Almeida, who has contributed to the studies of new bioactive molecules for multiple uses, and recently began to do prospective studies on Catasetinae. Distribution and habitat: ���This new natural hybrid has been collected on a fallen phorophyte in an anthropized forest de igap�� (floodplain) having suffered fire damage, on the river Mamuru in the municipality of Aveiro, PA, Brazil. Given that part of this river also runs in the Amazonas state we think that the taxon should also occur there. The putative parent species has also been observed in this area (see more below). According to Petini-Benelli (2020), C. boyi is distributed to the states of Amazonas and Par��. It has been registered to occur in the municipality of Aveiro on the basis of material collected by one of the present authors (J.B.F. da Silva) and deposited at MG (151046). Meanwhile, according to Petini-Benelli (2020) C. garnettianum has restricted distribution to the state of Amazonas. However, its occurrence in Par�� is also confirmed on the basis of material collected by one of the present authors (J.B.F. da Silva) in the municipality of Aveiro and deposited at MG (198317). The occurrence of putative parental species is therefore confirmed for the municipality where the new natural hybrid was found. Phenology and floral visitors: ���the flowering time of the new taxon occurs from June to August. As for the putative parental species, both can be observed flowering during the first half of the year, mainly between the months of April and June; between April and May for C. boyi and between February and June for C. garnettianum (personal observations by A.H. Krahl and J.B.F. da Silva). Thus, the flowering times of the taxa overlap at least partly in the area of the study, making the cross-pollination possible. Male bees of belonging to the genus Euglossa spp. (Euglossini) are the main floral visitors of the parental species (personal observations by J.B.F. da Silva). These bees appear to visit the flowers in order to collect volatile compounds present in the lip. Morphological affinities: ���the new entity presents a morphology that is intermediate between that of the two putative parents, C. boyi and C. garnettianum (Table 1). Vegetatively, Catasetum species are practically indistinguishable (Holst 1999, Walker-Larsen & Harder 2000). However, the new nothospecies has large pseudobulbs similar to those of C. boyi, rather than the short pseudobulbs reported for C. garnettianum (Petini-Benelli 2020). The leaves of C. �� sheyllae are oblanceolate, as in C. boyi, rather than oblong-lanceolate as in C. garnettianum (Petini-Benelli 2020). The most notorious features of C. �� sheyllae lie in the male flowers. The elliptic petals and lanceolate sepals are similar to those of C. garnettianum, whereas the lip is trilobed, as in C. boyi, rather than entire. The lip has a rounded sac as in C. boyi and shows the same small triangular erect acute calli at the base of both lateral lobes. The lateral lobes are ovate and erect (as in C. boyi) but their margins are laciniate. They are more similar to those of C. garnettianum, which has sparsely ciliate margin, rather than the denticulate margin of the lateral lobes with obliquely rising teeth seen in C. boyi. The median lobe is ovate as in C. boyi and oblong as in C. garnettianum. The margin of the new taxon is sparsely dentate as in C. garnettianum (margins sparsely ciliate) and shows a small tooth-like callus at apex, probably inherited from C. garnettianum that has a prominent callus at the lip apex (Rolfe 1888, Mansfeld 1930, Petini-Benelli 2020, table 1). The antennas are parallel and directed towards the center (parallel to convergent), as in C. boyi (Petini-Benelli 2020)., Published as part of Cantu��ria, Patrick De Castro, Krahl, Dayse Raiane Passos, Krahl, Amauri Herbert, Chiron, Guy & Silva, Jo��o Batista Fernandes Da, 2021, Catasetum �� sheyllae (Orchidaceae: Catasetinae), a new natural hybrid from Brazilian Amazon, pp. 257-265 in Phytotaxa 527 (4) on pages 259-262, DOI: 10.11646/phytotaxa.527.4.3, http://zenodo.org/record/5766200, {"references":["Petini-Benelli, A. (2020) Catasetum. Flora do Brasil 2020 by Jardim Botanico do Rio de Janeiro, JBRJ. Avaiable from: http: // floradobrasil. jbrj. gov. br / reflora / floradobrasil / FB 11312 (Accessed 6 July 2021).","Holst, A. W. (1999) The world of Catasetums. Timber Press, Portland, 560 pp.","Walker-Larsen, J. & Harder, L. D. (2000) The evolution of staminodes in Angiosperms: patterns of stamen reduction, loss, and functional re-invention. American Journal of Botany 87: 1367 - 1384. https: // doi. org / 10.2307 / 2656866","Rolfe, R. A. (1888) Catasetum garnettianum. The Gardeners Chronicle & Agricultural Gazette 2: 692.","Mansfeld, R. (1930) Catasetum boyi. Repertorium Specierum Novarum Regni Vegetabilis 28: 94. https: // doi. org / 10.1002 / fedr. 4870280603"]}

Submitted by Jorge Silva (jorgelmsilva@ufrrj.br) on 2022-08-04T18:42:53Z No. of bitstreams: 1 2021 - Jo?o Fernandes Fogel.pdf: 1452884 bytes, checksum: 93f16e7d63ccec6d8037bacf53e4b215 (MD5) Made available in DSpace on 2022-08-04T18:42:53Z (GMT). No. of bitstreams: 1 2021 - Jo?o Fernandes Fogel.pdf: 1452884 bytes, checksum: 93f16e7d63ccec6d8037bacf53e4b215 (MD5) Previous issue date: 2021-08-30 CAPES - Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior Passion fruit is a crop of great economic importance for Brazil. The country present itself as the major world producer of the fruit and also the major consumer. Lately, it is observed the growth of studies with genetic materials cultivated under organic management of passion-fruit crop cultures, what equally indicates the necessity of works focusing over the following the fertilization with organic sources attending nutritional requirements of the culture. Tephrosia sinapou is a shrub legume with potential for green manure and it is being almost not explored in the country. In this study was evaluated 1) Tephrosia vegetable biomass capacity as fertilizer for attending the nitrogen (N) demand for the passionfruit culture in organic production system, and 2) the decomposing rate and nitrogen (N) release from it?s biomass. The experiment was conducted in the Fazendinha Agroecol?gica Km 47, in the Serop?dica region conditions. For the first evaluated parameter it was adopted the randomized block design (RBD) with 4 treatments, 3 blocks and 3 repetitions. Where: Treatment 1 (T1) ? witness (without fertilization); Treatment 2 (T2) ? castor bean pie (CBP); Treatment3 (T3) ? Tephrosia fresh biomass (TFB); Treatment 4 (T4) a combination of 50% castor bean pie + 50% Tephrosia fresh biomass (CBP +TFB). In the second evaluated parameter, in relation to the determination of vegetable biomass decomposing of different parts of the plant (leaf, stalk, leaf + stalk) using litter bag methodology. It was adopted RBD and each distinct material considered a treatment, being 3 treatments, 3 blocks and 10 repetitions. The obtained results in this study demonstrated that the distinct parts of the plant presented distinct nitrogen decomposing and release times in function of C/N relation, being that as greater the C/N relation, greater were half-life (t1/2) times of the dry matter, being the leaf fraction with the minor half life time (38 days), followed by the leaft + stalk material (66 days) and the stalk (150 days). The half-life time nitrogen release of the leaf was the minor (29 days), followed by leaf + stalk material (38 days) and stalk (102 days). The castor bean pie (T2), for being a small C/N relation compost and quick nitrogen release, was the treatment with major total productivity (13,37 t ha-1), producing around 14% more than the witness treatment (11,5 t ha-1), 27% more than the treatment with Tephrosia biomass (9,7 t ha-1) e 10% more than the treatment with the mixture of castor bean pie (CBP) with Tephrosia (T4). The fertilization with Tephrosia biomass (T3) obtained productivity reduction around 15%, when compared with the witness treatment (T1), suggesting a lack of nitrogen for the sour passion-fruit cultivar of this treatment with the leguminous biomass, maybe due to the nitrogen immobilization in soil. The fertilization did not influence in the soluble solids content (oBrix). O maracujazeiro ? uma cultura de enorme import?ncia para a fruticultura brasileira. O pa?s apresenta-se como o maior produtor mundial da fruta e tamb?m o maior consumidor. Nos ?ltimos tempos, observa-se o crescimento de estudos com materiais gen?ticos cultivados sob manejo org?nico na cultura do maracujazeiro, o que igualmente imprime a necessidade de trabalhos focados no acompanhamento da aduba??o com fontes org?nicas que atendam ?s necessidades nutricionais da cultura. A tefr?sia (Tephrosia sinapou) ? uma leguminosa arbustiva com potencial para aduba??o verde e vem sendo pouco explorada no pa?s. Neste estudo foi avaliado 1) a capacidade da biomassa vegetal da tefr?sia como fertilizante para o atendimento da demanda de nitrog?nio (N) para a cultura do maracuj? amarelo em sistema org?nico de produ??o, e 2) a taxa de decomposi??o e libera??o de N da biomassa da tefr?sia. O experimento foi conduzido na Fazendinha Agroecol?gica Km 47, nas condi??es da baixada fluminense. Para o primeiro par?metro avaliado adotou-se o delineamento de blocos casualizados (DBC) com 4 tratamentos, 3 blocos e 3 repeti??es. Onde: Tratamento 1 (T1) ? testemunha (sem aduba??o); Tratamento 2 (T2) - torta de mamona (TM); Tratamento 3 (T3) - biomassa fresca de tefr?sia (BFT); Tratamento 4 (T4) a combina??o de 50% de torta de mamona + 50% de biomassa fresca de tefr?sia (TM+BFT). J? no segundo par?metro avaliado, relacionado a determina??o da decomposi??o da biomassa vegetal de diferentes partes da planta (folha, caule e folha + caule) foi utilizada a metodologia litter bag. Adotou-se o DBC e cada material distinto considerou-se um tratamento, sendo 3 tratamentos, 3 blocos e 10 repeti??es. Os resultados obtidos nesse estudo demonstram que as distintas partes da planta apresentaram tempos de decomposi??o e libera??o de nitrog?nio distintos em fun??o da rela??o C/N, sendo que, quanto maior a rela??o C/N, maiores foram os tempos de meia vida (t1/2) da mat?ria seca, sendo a fra??o foliar com o menor tempo de meia vida (38 dias), seguido do material de folha + caule (66 dias) e o caule (150 dias). O tempo de meia vida da libera??o de N na folha foi o menor (29 dias), seguido do material de folha + caule (38 dias) e do caule (102 dias). A torta de mamona (T2), por ser um composto com uma baixa rela??o C/N e r?pida libera??o do nitrog?nio, foi o tratamento com maior produtividade total (13,37 t ha-1), produzindo cerca de 14% a mais do que o tratamento testemunha (11,5 t ha-1), 27% a mais do que o tratamento com a biomassa da tefr?sia (9,7 t ha-1) e 10% a mais do que o tratamento com a mistura de torta de mamona com a biomassa da tefr?sia (11,92 t ha-1). O tratamento testemunha (T1) n?o diferiu significativamente da produtividade total do tratamento com a mistura da torta de mamona com tefr?sia (T4). A aduba??o com a biomassa da tefr?sia (T3) obteve redu??o da produtividade em torno de 15%, quando comparada com o tratamento testemunha (T1), o que sugere um d?ficit de nitrog?nio para a cultura do maracujazeiro neste tratamento com a biomassa da leguminosa, talvez devido a imobiliza??o do nitrog?nio no solo. A aduba??o n?o influenciou no teor de s?lidos sol?veis (?Brix) nos frutos do maracuj?.

The objective of the test suite is to validate commercial cloud services for the benefit of scientific workloads in multiple domains. The development of the test suite originates from the HNSciCloud project, where automation was lacking as tests deployments were executed manually, in a scattered manner with no result tracking capabilities. The initial version of the test suite has been developed during the OCRE project, and successfully deployed in a number of cloud providers before the existence of the OCRE Framework. Regarding the validation of cloud services under the OCRE Framework, access to the 27 cloud platforms present in OCRE will be necessary. To this end, CERN proposes to include an obligation to provide access to a billing account with a limited number of funds made available by the cloud vendors of the original 27 cloud platforms represented either directly or via resellers with contracts adjudicated through the OCRE Framework. This limited amount of funds will be used to validate cloud services in each of the platforms, to trial different configurations, billing controls, and to validate exit strategies. The test suite developed by CERN under an AGPL license is expected to become part of best practice, and to be adopted for on-boarding commercial cloud services to research environments in the context of the European Open Science Cloud (EOSC).

This work investigated the biotransformation of ginger constituents (zingerone, [6]-shogaol, [6]-gingerol, and methyl-[6]-gingerol) by the pathogenic fungus Colletotrichum gloeosporioides. Experiments were carried out with and without deuterium-labelled compounds. The product metabolites were analyzed by liquid chromatography coupled to tandem mass spectrometry and liquid chromatography solid phase extraction-nuclear magnetic resonance. Substrates supplied to the fungus were incorporated into metabolic pathways mostly by oxidation reactions, including aromatic carbon���carbon coupling. Zingerone and [6]-gingerol biotransformation products included biphenol dimers. A biodegradation pathway for biphenol formation was proposed based on the presence of the intermediate 4-(2-hydroxyethyl)-2-methoxyphenol, commonly identified from [6]-gingerol and [6]-shogaol biodegradation. This intermediate likely originates from a Baeyer���Villiger reaction followed by hydrolysis. The C���C coupling of molecules could result in phenolic oxidative ortho���ortho coupling, suggesting that biphenol dimers are products of C. gloeosporioides laccase catalysis.

Background & Aims: Individual risk for developing alcohol-related liver disease (ALD) varies greatly. We hypothesized that metabolic risk factors and genetic polymorphisms predict severity of ALD. Methods: Biopsy-controlled, cross-sectional study in patients with a history of excessive drinking. We measured the homeostatic model assessment of insulin resistance (HOMA-IR), plasma triglycerides, high- and low-density lipoproteins (HDL, LDL), and total cholesterol. Moreover, we genotyped four single nucleotide polymorphisms in PNPLA3 (rs738409C>G), TM6SF2 (rs58542926C>T), MBOAT7 (rs641738C>T), and HSD17B13 (rs72613567T>TA). We assessed predictors of higher fibrosis stage using multivariable ordered logistic regression. Results: Of 325 included patients, 25% had severe fibrosis or cirrhosis and 59% had HOMA-IR ≥2.5. HOMA-IR increased for each fibrosis stage, while there was a similar decrease in LDL and total cholesterol. Individuals with risk variant PNPLA3 rs738409-G or TM6SF2 rs58542926-T had higher fibrosis stage. In multivariable regression, HOMA-IR ≥2.5 (OR = 3.04, 95% CI 1.90-4.87), LDL

O presente trabalho foi realizado com apoio da Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - Brasil (CAPES) - C?digo de Financiamento 001. Submitted by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2021-03-25T19:27:53Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) graciene_fernandes_araujo_campos_fonseca.pdf: 1056717 bytes, checksum: b56a755c5ea44672468ccb494035d802 (MD5) Approved for entry into archive by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2021-03-25T19:28:41Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) graciene_fernandes_araujo_campos_fonseca.pdf: 1056717 bytes, checksum: b56a755c5ea44672468ccb494035d802 (MD5) Made available in DSpace on 2021-03-25T19:28:41Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) graciene_fernandes_araujo_campos_fonseca.pdf: 1056717 bytes, checksum: b56a755c5ea44672468ccb494035d802 (MD5) Previous issue date: 2020 Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) O treinamento f?sico ? um importante m?todo terap?utico n?o farmacol?gico para o tratamento e preven??o de diversas doen?as como a obesidade, a resist?ncia ? insulina e o diabetes mellitus tipo 2. O treinamento de subida em escadas para roedores pode ser uma estrat?gia para estudar os efeitos do treinamento no metabolismo da glicose. Anteriormente, nosso grupo de pesquisa observou que o treinamento de subida em escada foi capaz de melhorar a toler?ncia ? glicose e reduzir a adiposidade em camundongos alimentados com dieta hiperlip?dica. No presente estudo utilizamos amostras provenientes daquele estudo para analisarmos a resist?ncia ? insulina, a fun??o mitocondrial no tecido muscular e adiposo, e prote?nas envolvidas com a resist?ncia ? insulina no tecido muscular esquel?tico. Quarenta e oito animais foram divididos em 2 grupos (n=24) sendo grupo chow alimentado com ra??o comercial (10% das calorias de gordura) e grupo HFD (de high fat diet) alimentado com dieta hiperlip?dica (42% das calorias de gordura) por 12 semanas. Na quinta semana todos os animais foram adaptados para a subida em escada e passaram por testes f?sicos para determina??o da carga utilizada no treinamento. Os grupos foram subdivididos em grupos sedent?rios e grupos treinados (n=12/grupo). Na sexta semana experimental se deu o in?cio do protocolo de treinamento de forma progressiva que durou por 6 semanas. O treinamento de for?a de subida em escada melhorou a resist?ncia ? insulina e aumentou o conte?do e fosforila??o de prote?nas relacionadas ao metabolismo de glicose que estavam alterados no animais sedent?rios alimentados com dieta hiperlip?dica. O presente estudo mostrou que o treinamento de for?a de subida em escada foi capaz de melhorar a resist?ncia ? insulina, provavelmente por modular prote?nas intracelulares relacionadas ? via de sinaliza??o da insulina. Disserta??o (Mestrado) ? Programa Multic?ntrico de P?s-gradua??o em Ci?ncias Fisiol?gicas, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2020. Physical training is an important non-pharmacological therapeutic method for the treatment and prevention of diseases such as obesity, insulin resistance and type 2 diabetes mellitus. Rodent ladder training can be a strategy to study the effects of training without glucose metabolism. Previously, our research group noted that stair climbing training was able to improve glucose tolerance and reduce adiposity in mice fed a high-fat diet. In the present study, we used data from that study to analyze insulin resistance, mitochondrial function in muscle and adipose tissue, the proteins involved with insulin resistance in skeletal muscle tissue. Forty-eight animals were divided into 2 groups (n = 24) with a chow group fed commercial feed (10% of the fat calories) and an HFD group (on a high fat diet) fed with a high fat diet (42% of the fat calories) by 12 weeks. In the fifth week, all animals were adapted to climb stairs and underwent physical tests to determine the load used in training. The groups were subdivided into sedentary groups and trained groups (n = 12 / group). In the sixth experimental week, the training protocol started progressively, which lasted for 6 weeks. Stair climbing strength training improved insulin resistance and increased protein content and phosphorylation related to glucose metabolism that was altered in sedentary animals fed a high-fat diet. The present study showed that stair climbing strength training was able to improve insulin resistance, probably due to modular intracellular proteins related to the insulin signaling pathway.

In 1782 Jos�� Monteiro da Rocha, astronomer and professor of the University of Coimbra, presented in a public session of the Royal Academy of Sciences of Lisbon a memoir on the problem of the determination of the comets' orbits. Only in 1799, the "Determina����o das Orbitas dos Cometas" (Determination of the orbits of comets) would be published in the Academy's memoires. In that work, Monteiro da Rocha presents a method for solving the problem of the determination of the parabolic orbit of a comet from three observations. Monteiro da Rocha's method is essentially the same method proposed by Olbers and published under von Zach's sponsorship two years before, in 1797. To have been written and published in Portuguese was certainly a hindrance for its dissemination among the international astronomical community. In this article, we intend to present Monteiro da Rocha's method and trying to see to what extent Gomes Teixeira's assertion (Teixeira 1934) that Monteiro da Rocha and Olbers must figure together in the history of astronomy, as the first inventors of a practical and easy method for the determination of parabolic orbits of comets, is justified., Accepted in Journal for the History of Astronomy

The European Human Biomonitoring Initiative (HBM4EU) is a joint effort of 28 countries(24 European Member States, three associated countries and Switzerland), the EuropeanEnvironment Agency and the European Commission, co-funded under Horizon2020. The main objective of HBM4EU is to use Human Biomonitoring (HBM) to assess human exposure to chemicals in Europe in order to better understand the associated health impacts and to improve chemical risk assessment. HBM4EU will generate knowledge on chemical exposure levels in the population and their health effects. In parallel to HBM studies, health examination surveys (HES) are conducted in many European countries. HES are surveys where information collected by questionnaire(s) is complemented with information obtained by physical measurements such as blood pressure and anthropometric measurements, and by analysis of biomarkers from biological samples. The European Health Examination Survey (EHES)was established in 2010 to coordinate the development of national HESs in Europe. Between 2000 and 2017, 15 European countrieshave conducted a national HES and in many countries smaller, regional or disease specific surveys have been carried out. Since for both HBM studies and HESs, data is collected through fieldwork, which is one of the largest expenses for such studies and needed infrastructures are very similar, the potential to combine these two types of studies has been considered. This could result in more cost-effective ways to conduct health and environmental monitoring. In some countries, such as Germany, Israel and France, this combination has already been done at national or regional level. Human Biomonitoring and health studies have a lot of similarities in terms of the infrastructure and procedures required for their implementation. However, in practice, the opportunity for adding a HBM module to an ongoing/planned health study (and vice versa) is rarely used. Reasons for this may be multifarious and may differ from country to country, and between different study settings. This report will look at different aspects related to combining HBM and health studies, together with possibilities for mortality and morbidity follow-up through linkage to administrative registers. This report will also provide information about identified and possible health effects related to the chemical exposures and how to directly measure those health effects. WP14 has worked in more detail on effect biomarkers for different health effects.3 Therefore, this report has four main parts: Part A. Opportunities and obstacles of combining HBM and health studies Part B. Availability of administrative registers and possibilities for their use in HBM studies Part C. Measuring potential health effects of the priority substances Part D. SOPs for selected health measurements.

Nesta dissertação, fazemos uma discussão teórica e metodológica sobre o que determina fundamentalmente as lutas de emancipação. Em primeiro lugar, identificamos como a consciência é tomada no senso comum como sendo esse fator determinante. Passamos então a analisar alguns trabalhos acadêmicos da Psicologia e das Ciências Humanas que tomam como pressuposto que a consciência de fato ocupa esse lugar. Eles têm em comum algumas características metodológicas: por meio de entrevistas, recolhem dados empíricos sobre o que os trabalhadores pensam e classificam suas consciências em diversos níveis, alguns mais próximos outros mais distantes da possibilidade de emancipação. Nestes trabalhos, criticamos uma concepção de Humano dualista, que cinde corpo e espírito, e identificamos em tal concepção uma impossibilidade de se propor ações efetivas. Em seguida, por meio do recurso ao pensamento dialético, construímos uma concepção monista de sujeito, que foge à cisão e que seria capaz de apontar para uma prática de fato emancipatória. Para compreender de forma mais concreta as possibilidades de emergência desse sujeito na luta de classes, estabelecemos um diálogo com Lukács e suas formulações sobre consciência de classe. Esse autor faz uma tentativa de construir uma teoria materialista e dialética sobre o tema. A consciência de classe dos trabalhadores é, para ele, aquela consciência psicológica necessária para que eles cumpram a meta revolucionária de sua classe, e não a consciência psicológica empiricamente observada. Apesar de Lukács superar os trabalhos empíricos anteriormente citados, também criticamos sua formulação por cair no idealismo e em uma perspectiva política fatalista, que igualmente não é capaz de informar a ação de emancipação. Por fim, a partir de uma crítica materialista aos elementos idealistas que identificamos em Lukács, propomos uma hipótese sobre a determinação fundamental das lutas emancipatórias: tal determinação teria mais relação com a organização dos trabalhadores do que com sua consciência ou com qualquer outro aspecto ideal. Nossa hipótese ainda não é suficientemente aprofundada nesta dissertação, mas apontamos caminhos para delimitá-la e testá-la melhor, a partir de critérios teóricos e históricos In this dissertaton, we present a theoretcal and methodological discussion about what fundamentally determines the struggles for emancipaton. At frst, we identfy that consciousness is popularly taken as if it were the determinant factor in this regard. Then, we analyze a few academic studies from the feld of Psychology and the Human Sciences, which assume that consciousness indeed occupies this determining role in class struggle. They have some methodological features in common: through interviews, they harvest empirical data about what workers think, and, aferwards, rank their consciousnesses in diferent levels, some closer to and some further from the possibility of emancipaton. We critcize, within these researches, a dualist concepton of Human, that splits body and spirit, identfying in such a concepton the impossibility of proposing efectve agency to workers. Furthermore, we call upon the dialectcal reasoning and build a monist concepton of subject, denying the split and trying to enlighten a path to emancipatory practces. To concretely comprehend the possibilites of this kind of subjects emergence in class struggle, we establish a dialogue with Lukács and his formulatons on class consciousness. This author intends to theorize materialistcally and dialectcally about this issue. Class consciousness of workers, for him, is not the empirically observed consciousness, but the psychological consciousness necessary for them to accomplish the revolutonary goal of their class. Despite Lukács surpassing the empirical studies previously mentoned, we also critcize his formulatons because he backslides on idealism and a politcal fatalism, equally unable to guide the acton towards emancipaton. At last, out of materialistc critcism we bring onto idealistc elements in Lukács, we propose a hypothesis on the fundamental determinant of emancipatory struggles: such determinant is more closely related to the organizaton of workers than to their consciousness or any other ideal aspect. Our hypothesis is not yet sufciently explored as of this dissertaton, but here we point towards paths to beter bound it with theoretcal and historical criteria

In this paper we modify and generalize a construction presented by Novotn��: given a groupoid (a set equipped with a binary operation), it is defined a mono-unary algebra corresponding to that specific groupoid. We shall introduce and study a functor from the category of n-ary groupoids to the category of mono-unary algebras. The main result of this paper concerns the construction of homomorphisms between n-ary groupoids, a natural generalization of the method presented by Novotn��., The author was notified that the constructions described in the paper were already described in Construction of all homomorphisms of mono-n-ary algebras, Czechoslovak Mathematical Journal, Vol. 46 (1996), No. 2, 331--333

Submitted by Celso Magalhaes (celsomagalhaes@ufrrj.br) on 2017-05-03T14:33:01Z No. of bitstreams: 1 2016 - Jo?o Kleber da Costa Fernandes.pdf: 3419179 bytes, checksum: 438592497d93b0e2004465d0aa5c057c (MD5) Made available in DSpace on 2017-05-03T14:33:01Z (GMT). No. of bitstreams: 1 2016 - Jo?o Kleber da Costa Fernandes.pdf: 3419179 bytes, checksum: 438592497d93b0e2004465d0aa5c057c (MD5) Previous issue date: 2016-04-29 Lauraceae Juss. is a pantropical and economically important plant family, consisting of 50 genera and approximately 3,000 species, mostly found in humid forests. Several species are important resource in the construction timber, spice, essential oil, and medicinal plants. Among the 22 genera of Lauraceae occurring in Brazil, Urbandodendron Mez. is a genus with three species found in Southeastern Brazil and in Bahia state. Due to the complexity of that group, several classification systems have been proposed to the family. The most recent system suggests the division of the Lauroidea subfamily into three tribes, based on inflorescence morphology and on characters of wood and bark anatomy. On the other hand, Urbanodendron has not been included in that classification, since there are no studies on wood anatomy for that genus up to date. This study aims to provide information that can support Lauraceae taxonomy by describing wood characters of Urbanodendron bahiense (Meisn.) and U. verrucosum (Ness) Mez., followed by a literature review on the wood anatomy of other 21 genera of Lauraceae. Wood samples of both species were collected with an increment borer and processed based on usual techniques of optical and scanning electron microscopy. In order to verify if environmental factors may affect wood structure, samples were collected in Lowland and Submontane Ombrophilous Dense Forest remnants located in two conservation units in Rio de Janeiro state, the Parque Natural Municipal do Curi? and the Reserva Biol?gica de Po?o das Antas. A Principal Coordinates Analysis (PCoA) was used to evaluate how wood anatomy characters may support an intrafamiliar diagnosis in Lauraceae. The comparative analysis between the wood anatomies of U. bahiense e U. verrucosum indicated a homogeneous wood structure for both species, as observed in the other genera of Lauraceae, showing the following wood anatomical characters: growth ring boundaries distinct; porosity diffuse, solitary vessels and radial multiplex of 2-4, circular to oval outline, exclusively simple perforation plates, alternate intervessel pits; septate fibre; axial parenchyma paratracheal vasicentric; uniseriate and multiseriate (2-3 cells) rays; presence of phenolic compounds, mucilage and oil cells. Both species differ only in the location and frequency of oil/mucilage cells. The PCoA showed that wood anatomical characters effectively supported the diagnosis of tribes Cryptocaryeae, Laureae and Perseeae. The structure of the secondary xylem in Urbanodendronhave characters which are common to genera Aniba, Licaria, Nectandra, Ocotea and Persea, all belonging to tribe Perseeae, suggesting the placement of Urbanodendron in that same tribe. There were no quantitative statistically significant differences between cell elements present in individuals from both forest remnants. Lauraceae Juss. ? uma fam?lia de grande import?ncia econ?mica sendo empregada na culin?ria, na perfumaria e na ind?stria farmac?utica, na fabrica??o de papel, em marcenaria e constru??o civil. As esp?cies t?m distribui??o pantropical, ocorrem nas florestas tropicais e subtropicais, em ambientes ?midos. A fam?lia ? constitu?da por 50 g?neros e aproximadamente cerca de 3.000 esp?cies. No Brasil s?o encontrados 22 g?neros, dentre eles Urbandodendron Mez, constitu?do por tr?s esp?cies, cuja distribui??o est? restrita aos estados do Sudeste e Bahia. Diversas classifica??es foram propostas devido a complexidade do grupo. O sistema de classifica??o mais recente sugere a divis?o da subfam?lia Lauroidea em tr?s tribos baseada na morfologia da infloresc?ncia e na anatomia do lenho e da casca. No entanto, Urbanodendron n?o ? citado nesta classifica??o, devido aus?ncia de estudos sobre a anatomia do lenho para o g?nero, at? o momento. O presente estudo tem como objetivo fornecer subs?dios ? taxonomia de Lauraceae, por meio da descri??o das caracter?sticas do lenho de Urbanodendron bahiense (Meisn.) e U. verrucosum (Ness) Mez, e de uma revis?o sobre a anatomia do lenho de 21 g?neros pertencentes ? fam?lia. Al?m de avaliar se as varia??es ambientais encontradas em Floresta Ombr?fila Densa de terras baixas e submontana promovem mudan?as significativas na estrutura do lenho. As amostras foram coletadas atrav?s de m?todos n?o destrutivos e processadas de acordo com as t?cnicas usuais para observa??o do lenho em microscopia ?ptica e microscopia eletr?nica de varredura. Os indiv?duos provem de duas ?reas de estudo do estado do Rio de Janeiro: O Parque Natural Municipal do Curi? e a Reserva Biol?gica de Po?o das Antas. Para a revis?o foram feitos levantamentos em bases de dados e peri?dicos especializados. A an?lise de coordenadas principais (PCoA) foi utilizada para avaliar como os caracteres anat?micos do lenho podem auxiliar no diagn?stico infrafamiliar em Lauraceae A partir do estudo comparativo da anatomia do lenho de U. bahiense e U. verrucosum foi poss?vel verificar que o lenho apresenta uma estrutura homog?nea como os demais g?neros da fam?lia, que incluem: camadas de crescimento distintas; porosidade difusa, vasos solit?rios e m?ltiplos radiais de 2-4 c?lulas, placa de perfura??o exclusivamente simples e pontoa??es intervasculares alternas; fibras septadas; par?nquima axial paratraqueal vasic?ntrico; raios unisseriados e multisseriados (2-3 c?lulas), integrados por c?lulas procumbentes na por??o central e eretas ou quadradas nas margens; presen?a de subst?ncias fen?licas, c?lulas ole?feras/mucilaginosas associadas ao raio. As esp?cies estudadas diferiram apenas na localiza??o e frequ?ncia das c?lulas ole?feras/mucilaginosas. A an?lise de coordenadas principais mostrou que os caracteres anat?micos do lenho auxiliam no diagn?stico das tribos Cryptocaryeae, Laureae e Perseeae. A estrutura do xilema secund?rio de Urbanodendron apresenta caracteres comuns aos g?neros Aniba, Licaria, Nectandra, Ocotea e Persea que pertencem ? tribo Perseeae, sugerindo o posicionamento do g?nero estudado nessa mesma tribo. A an?lise quantitativa dos elementos celulares encontrados nos indiv?duos de ambas as esp?cies, das duas forma??es vegetais, n?o apresentou diferen?as estat?sticas

Data de aprova??o ausente. Submitted by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2017-02-13T18:51:06Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) tatiana_fernandes_araujo_almeida.pdf: 2531556 bytes, checksum: 11a2583c0414dc55d6f907a2566a4de5 (MD5) Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2017-03-06T12:21:52Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) tatiana_fernandes_araujo_almeida.pdf: 2531556 bytes, checksum: 11a2583c0414dc55d6f907a2566a4de5 (MD5) Made available in DSpace on 2017-03-06T12:21:52Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) tatiana_fernandes_araujo_almeida.pdf: 2531556 bytes, checksum: 11a2583c0414dc55d6f907a2566a4de5 (MD5) Previous issue date: 2016 O carcinoma espinocelular oral (CECO) ? uma neoplasia maligna que acomete principalmente idosos. O desencadeamento da doen?a ? relacionado ? exposi??o aos fatores de risco e ao decl?nio da fun??o imune associada ao envelhecimento cronol?gico. Alguns estudos t?m demonstrado um aumento na incid?ncia de CECO em adultos jovens, sugerindo envolvimento de outros fatores na etiologia da doen?a, como uma altera??o do sistema imunol?gico. As c?lulas dendr?ticas (CDs) s?o c?lulas apresentadoras de ant?geno profissionais e estimuladoras eficazes para a expans?o clonal de linf?citos. Acredita-se que uma altera??o da fun??o das CDs em pacientes com c?ncer contribui para a falha da resposta antitumoral, levando a uma consequente progress?o da doen?a. O objetivo deste estudo foi avaliar, atrav?s da imunoistoqu?mica, se h? diferen?a na quantifica??o tissular dos subgrupos de CDs, associada ? idade, em esp?cimes de bi?psias de CECO. Para isso, foram selecionados casos de CECO de pacientes em tr?s diferentes faixas et?rias: G1 (< 40 anos de idade, n = 12), G2 (? 40 at? < 60 anos de idade, n = 15) e G3 (? 60 anos de idade, n = 14). Os marcadores utilizados foram S100, CD1a, CD207 (para CDs imaturas, imCDs), CD83 e CD208 (para CDs maduras, mCDs). As imagens foram capturadas dos campos com maior intensidade de marca??o nas l?minas histol?gicas e a quantifica??o celular foi realizada com o aux?lio do software Image J. A frequ?ncia e localiza??o das CDs foram avaliadas e analizadas estatisticamente nas regi?es intratumoral (intertumoral e ou estromal) e extratumoral. No geral, imCDs foram significativamente mais frequentes que mCDs em todos os grupos. ImCDs e mCDs mostraram preferencialmente localiza??o intratumoral e extratumoral respectivamente. Comparando G1 versus G2 / G3 foi observada um significativo menor n?mero de mCDs em G1. Na compara??o de G1 em rela??o a G2 ou G3 houve um n?mero significativamente menor de ambas, imCDs e mCDs. Nossos resultados mostram que existe uma menor quantidade de imCDs e mCDs em CECO afetando pacientes jovens em compara??o com idosos, sugerindo um comprometimento da resposta imune antitumoral em G1e permitindo a progress?o do tumor. Disserta??o (Mestrado) ? Programa de P?s-Gradua??o em Odontologia, Universidade Federal dos Vales do Jequitinhonha e Mucuri, [2016]. Oral squamous cell carcinoma (OSCC) is a malignant neoplasm that mainly affects elderly people. The onset of the disease is related with exposure to risk factors and the decline of immune function associated with chronological aging. Previous studies have demonstrated an increased incidence of CECO in young adults, suggesting involvement of other factors in the etiology of the disease, such as a change in the immune system. Dendritic cells (DCs) are professional antigen presenting cells and effective for stimulating clonal expansion of lymphocytes. It is believed that a change in the function of DC in cancer patients contributes to the failure of the anti-tumor response, leading to a consequent progression of the disease. The aim of this study was to evaluate, by immunohistochemistry, if there were differences in tissue quantification of DCs subsets, associated with age in specimens of OSCC biopsies. For this OSCC cases were selected at three different ages: G1 (< 40 years old, n = 12), G2 (? 40 to

Business simulation games are considered as effective tools for the empowerment and mediation of business content learning. They act as serious games which contribute to learning through a simulation of real-life situations and business environments. They are especially useful in the area of business management processes and business strategies. The blending of designed simulation technology and content curricula offers participants (players, students) a risk-free opportunity to test out a range of relevant strategies to drive business results. By customizing computer-based business simulations, participants can integrate key strategic and financial priorities. This paper provides a brief review of business simulations that serve learning purposes. The first part presents a short introduction and description of business games and their evaluation properties, and the second part provides a brief evaluation and analysis of selected business simulation games.

One of the most important assets of any company is being able to easily access information on itself and on its business. In this line, it has been observed that this important information is often stored in one of the millions of spreadsheets created every year, due to simplicity in using and manipulating such an artifact. Unfortunately, in many cases it is quite difficult to retrieve the intended information from a spreadsheet: information is often stored in a huge unstructured matrix, with no care for readability or comprehensiveness. In an attempt to aid users in the task of extracting information from a spreadsheet, researchers have been working on models, languages and tools to query. In this paper we present an empirical study evaluating such proposals assessing their usage to query spreadsheets. We investigate the use of the Google Query Function, textual model-driven querying, and visual model-driven querying. To compare these different querying approaches we present an empirical study whose results show that the end-users' productivity increases when using model-driven queries, specially using its visual representation.

This book focuses on various topics related to engineering and management of requirements, in particular elicitation, negotiation, prioritisation, and documentation (whether with natural languages or with graphical models). The book provides methods and techniques that help to characterise, in a systematic manner, the requirements of the intended engineering system. It was written with the goal of being adopted as the main text for courses on requirements engineering, or as a strong reference to the topics of requirements in courses with a broader scope. It can also be used in vocational courses, for professionals interested in the software and information systems domain. Readers who have finished this book will be able to: - establish and plan a requirements engineering process within the development of complex engineering systems; - define and identify the types of relevant requirements in engineering projects; - choose and apply the most appropriate techniques to elicit the requirements of a given system; - conduct and manage negotiation and prioritisation processes for the requirements of a given engineering system; - document the requirements of the system under development, either in natural language or with graphical and formal models. Each chapter includes a set of exercises.

This book contains the refereed proceedings of the 6th International Conference on Software Business, ICSOB 2015, held in Braga, Portugal, in June 2015. The theme of the event was "Enterprising Cities" focusing on a noticeable spillover of software within other industries enabling new business models: Companies bundle their physical products and software services into solutions and start to sell independent software products in addition to physical products. The 16 full, five short, and three doctoral symposium papers accepted for ICSOB were selected from 42 submissions. The papers span a wide range of issues related to contemporary software business—from strategic aspects that include external reuse, ecosystem participation, and acquisitions to operational challenges associated with running software business.

Spreadsheets are widely used, and studies have shown that most end-user spreadsheets contain nontrivial errors. To improve end-users productivity, recent research proposes the use of a model-driven engineering approach to spreadsheets. In this paper we conduct the first systematic empirical study to assess the effectiveness and efficiency of this approach. A set of spreadsheet end users worked with two different model-based spreadsheets, and we present and analyze here the results achieved., 14 Pages, 9 Colour Figures, 2 Tables; Proc. European Spreadsheet Risks Int. Grp. (EuSpRIG) 2011, ISBN 978-0-9566256-9-4

Background and context Creativity and innovation remain vital ingredients to the success of any organisation. Working in silo can stifle teams from maintaining interest in the activities of the wider hospice workforce. A challenge for many clinical teams is to encourage and stimulate the generation of new ideas and innovations that can benefit and sustain a wider and future workforce including addressing the needs of pre-registration nursing students. The hospice in-patient unit established the need for a means of communicating key information/resources to highlight the practices beyond the IPU. Aim To create a resource tool for clinical staff and student nurses to share and disseminate information, forging links and engagement with the wider palliative care teams. For the tool to support the future re-validation process for Registered Nurses. Approaches Development of a colourful, attractive “pick n mix” resource board incorporatingthe hospice logo detailing 26 varied opportunities for staff to engage with the wider multi-disciplinary team, and experience local and national services allied to our care. This tool was developed by a qualified member of the nursing team in the In-Patient Unit and is updated by its originator on a weekly basis to reflect the varied and changing learning opportunities in the Hospice and the wider community. In addition, the board identifies mandatory training and clinical competencies. This acts as a prompt for staff to acknowledge their personal responsibility to the Hospice and the NMC. Outcomes The ‘pick n mix9 board raised awareness of the diverse ways in which we deliver evidence based end of life care. It enhanced creative thinking and encouraged nurses to remain updated. Formal evaluations of the number of study leave applications pertaining to the 26 learning opportunities will be audited. A six month review of the success of the tool will take place through group discussions and an anonymised evaluation form.

Cadernos BAD, N.�� 1 (1983)

Introduction Communication skills training is traditionally directed towards clinicians. At St Francis we identified a need to support our fundraising staff in their confidence in their daily conversations. These conversations often included distressed bereaved relatives. Aims To increase the communication skills and confidence of fundraising staff in the community and public setting. Methods A ½ day interactive workshop using videoed role play with a Connected actor, facilitator and communication skills trainer. The role play was based upon scenarios provided by the fundraisers prior to the workshop. They completed a pre and post workshop confidence questionnaire and a follow-up one 3 months later. Results 11 fundraising staff attended. Scenarios revolved around distressed relatives (expected and unexpected), and questions about care and dying in the context of fundraising for the hospice. Pre and post course questionnaires showed an increase in confidence in challenging conversations. The workshop was highly evaluated. Discussion ▶Fundraising staff do not necessarily have the day to day experience of clinical conversations to draw upon, but bereaved families have the same expectations of them as clinical staff in terms of conveying empathy and compassion. ▶There is a parallel agenda of empathy versus receiving a donation, eliciting a “story” or discussing a fundraising event. ▶The communication challenges are similar to clinicians and the power of silence is a similar take home message. ▶The advantages of using videoed role play include giving participants the chance to see and discuss things they might have missed first time around. Conclusion Fundraising staff have similar communication training motivation as clinical staff. The workshop was a worthwhile education event, albeit seeming too short – in the future it would be beneficial to mix more non-clinical staff to give a wider breadth of discussion and experience – this is planned for later in 2011.

Aims Through the catalyst of ‘pony experience’ bereaved children and parents are facilitated into meaningful conversations with each other and supportive relationships with other families. Method Once a month bereaved children and families are invited to meet in the Hospice Woodland Walk for Pony Experience, including grooming and riding. Results ▶Commonalty of experience: participants meet other bereaved families, enabling them to share “their stories” should they wish and develop co -supportive relationships. ▶Children gain confidence – “Life will go on even without their loved one” ▶Observing other children confirms they are not alone, seeing others having fun gives permission for them to do likewise. ▶Walking side by side feels less intense, enabling easy conversation and ability to explore and chat at differing levels. ▶This informal bereavement group work is well attended with positive oral feedback. Formal evaluation underway- results pending. Discussion Benefits Children feel more at ease when handling a pet or when being “carried” by a pony. They can use the animal as distraction from uncomfortable conversations to disclose intimacies/memories that may otherwise be difficult. Challenges Gaining insurance for the pony component proved challenging but possible. Health and safety issues require stringency. Conclusion Intrinsic to palliative care and bereavement support is focusing upon the little things that make a person feel respected and loved. We have launched a project that is simple in its theory, but complex and diverse in its positive outcomes. Recommendations We appeal to all Hospices to explore whether they could use pets in similar ways to support children requiring essential but difficult pre and post bereavement care. Oral presentation will include photos (consented)and interviews from users.