1. Ocular Adverse Events following Yellow Fever Vaccination: A Case Series
- Author
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Rodolfo Bonatti, André Carvalho Kreuz, Marta Heloísa Lopes, Fernanda Crotti, Renato Rodrigues Pereima, Joyce Hisae Yamamoto, and João M. Furtado
- Subjects
Adult ,Vogt–Koyanagi–Harada disease ,medicine.medical_specialty ,genetic structures ,Disease Outbreaks ,Yellow fever vaccination ,Yellow Fever ,VASCULITE ,medicine ,Humans ,Immunology and Allergy ,Child ,Adverse effect ,business.industry ,Vaccination ,Yellow fever ,medicine.disease ,Dermatology ,eye diseases ,Ophthalmology ,Central Serous Chorioretinopathy ,sense organs ,business ,Vasculitis ,Brazil - Abstract
To describe four cases of ocular adverse events resembling intraocular inflammatory and non-inflammatory conditions following yellow fever vaccination (YFV) during a recent yellow fever (YF) outbreak in Brazil.Charts of patients diagnosed with ocular adverse events after YFV between January 2017 and January 2019 at two tertiary referral centers in Brazil.Four patients (two adults and two children) are reported. Case 1 presented with typical findings of central serous chorioretinopathy which resolved spontaneously; case 2 was diagnosed with acute Vogt-Koyanagi-Harada disease; cases 3 and 4 had bilateral diffuse retinal vasculitis. In the absence of infectious and noninfectious disorders, the temporal association between stand-alone YFV and onset of ocular symptoms within 15 days was interpreted as evidence of causation.Clinicians should be aware of the wide spectrum of possible ocular adverse reactions to stand-alone YFV.
- Published
- 2021
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