Search

Your search keyword '"Feng, Xiangru"' showing total 187 results
Start Over Author "Feng, Xiangru"
187 results on '"Feng, Xiangru"'

27. Mesoporous silica SBA-15 composite for the delivery of amoxicillin against S. aureus skin infection.

Author

Wang, Qingshuang, Cui, Yurui, Ai, Wei, Li, Siqi, Zhang, Zhe, and Feng, Xiangru

Subjects
SKIN infections, MESOPOROUS silica, AMOXICILLIN, ESCHERICHIA coli, DRUG carriers, DRUG resistance in bacteria
Abstract

Currently, frequent and extensive usage of antibiotics is a common treatment for skin infections, which might increase the risk of bacterial resistance. With the emergence of local administration, much attention has been focused on developing a drug carrier for sustained drug release at the infected site. In this study, we synthesized ordered mesoporous silica SBA-15 and amino group-decorated SBA-15 (NH2-SBA-15) for the delivery of the antibiotic amoxicillin. Both nanocomposites had a high drug loading content, showed continuous drug release, and presented an evident anti-bacterial effect against E. coli and S. aureus. By local subcutaneous injection of amoxicillin-loaded nanocomposites, the S. aureus skin infection of mice was well alleviated, and wound recovery was improved. The SBA-15-based drug carrier reduced the frequency of administration and thereby provided a promising prospect for the controlled and sustained release of antibiotics for skin infections. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

30. Underwater wet laser cladding on 316L stainless steel: A protective material assisted method

Author

Lu Bingwen, Fang Yongchao, Wen Xin, Xiufang Cui, Guo Jin, Zhaobing Cai, Zhao Yao, and Feng Xiangru

Subjects
010302 applied physics, Energy loss, Materials science, 02 engineering and technology, engineering.material, 021001 nanoscience & nanotechnology, Laser, Microstructure, 01 natural sciences, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, law.invention, Corrosion, Coating, law, 0103 physical sciences, engineering, Laser power scaling, Electrical and Electronic Engineering, Underwater, Composite material, 0210 nano-technology, Laser processing
Abstract

In this paper, a new underwater processing technology was proposed, called underwater wet laser cladding (UWLC). Protective material assisted UWLC was provided to increase the processed water depth of UWLC and promote the quality of UWLC coatings without changing the laser power. For comparison, the direct UWLC and protective material assisted UWLC were performed under various water depths with uniform experimental parameters. The UWLC processes under water depth of 15 mm were studied in detail. The blue-purple plasma appears during the direct UWLC processes leading to the failure of UWLC. The mental plume appears during the protective material assisted UWLC processes. In addition, the protective material assisted UWLC is more likely to succeed by increasing the content of protective material. The 316L stainless steel coatings were successfully prepared by protective material assisted UWLC. The microstructure of the 316L coatings by protective material assisted UWLC is well in agreement with 316L coatings prepared by laser cladding in air, while the 316L coating by direct UWLC is mainly composed of columnar dendrites. Moreover, the corrosion resistance of 316L coating by direct UWLC in 3.5 wt.% NaCl solutions is improved markedly by applying protective material. The energy loss in the process of underwater wet laser processing is significantly reduced through the protective material assisted method, which provides meaningful theoretical support for underwater wet laser repair.

Published
2019

48. Immunomodulatory Nanosystems

Author

Feng, Xiangru, primary, Xu, Weiguo, additional, Li, Zhongmin, additional, Song, Wantong, additional, Ding, Jianxun, additional, and Chen, Xuesi, additional

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results