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Recently,knowledge base(KB) has been widely adopted to the task of question answering(QA) to provide a proper answer for a given question,known as the KBQA problem.However,knowledge base itself may be incomplete(e.g.KB does not contain the answer to the question,or some of the entities and relationships in the question),limiting the overall performance of existing KBQA models.To resolve this issue,this paper proposes a new model to leverage textual documents for KBQA task by providing additional answers to enhance knowledge base coverage and background information to enhance the representation of questions.Specifically,the proposed model consists of three modules,namely entity and question representation module,document and enhanced-question representation module and answer prediction module.The first module aims to learn the representations of entities from the retrieved subgraph of knowledge base.Then,the question representation can be updated with the fusion of seed entities.The second module attempts to learn a proper representation of the document that is relevant to the given question.Then,the question representation can be further improved by fusing the document information.Finally,the last module makes an answer prediction based on the information of knowledge base,updated question and documents.Extensive experiments are conducted on the WebQuestionsSP dataset,and the results show that better accuracy can be obtained in comparison with other counterparts.

By reasonably simplifying the three-dimensional model of the gearbox of the nuclear power circulating pump, a moving particle semi-implicit method is used to simulate the forced oil injection lubrication flow field of the nuclear power gearbox. The movement state of the complex flow field inside the gearbox is accurately and quickly obtained. The effects of the injection angle, the oil supply force and other injection parameters on the oil flow characteristics in the gearbox are studied; the parameter changes of oil particles near the inner and outer meshing areas and the influence mechanism of oil distribution on the lubrication behavior of planetary gears are analyzed. Results show that high-speed particles are concentrated in the outer meshing region, while the low-speed particles are mainly distributed on the surface of the ring gear and the inner meshing region. The effects of injection parameters on particle fluidity in inner and outer meshing regions are different. The optimization design of forced lubrication shall take into consideration of the lubrication characteristics of different areas.

BACKGROUND: Flax lignan has attracted much attention because of its potential bioactivities. However, the bioavailability of secoisolariciresinol diglucoside (SDG), the main lignan in flaxseed, depends on the bioconversion by the colon bacteria. Lactic acid bacteria (LAB) with β‐glucosidase activity has found wide application in preparing bioactive aglycone. RESULTS: LAB strains with good β‐glucosidase activity were isolated from fermented tofu. Their bioconversion of flax lignan extract was investigated by resting cell catalysis and microbial fermentation, and the metabolism of SDG by Lactiplantibacillus plantarum C5 following fermentation was characterized by widely targeted metabolomics. Five L. plantarum strains producing β‐glucosidase with broad substrate specificity were isolated and identified, and they all can transform SDG into secoisolariciresinol (SECO). L. plantarum C5 resting cell reached a maximum SDG conversion of 49.19 ± 3.75%, and SECO generation of 21.49 ± 1.32% (0.215 ± 0.013 mm) at an SDG substrate concentration of 1 mM and 0.477 ± 0.003 mm SECO was produced at 4 mm within 24 h. Although sixteen flax lignan metabolites were identified following the fermentation of SDG extract by L. plantarum C5, among them, four were produced following the fermentation: SECO, demethyl‐SECO, demethyl‐dehydroxy‐SECO and isolariciresinol. Moreover, seven lignans increased significantly. CONCLUSION: Fermentation significantly increased the profile and level of flax lignan metabolites, and the resting cell catalysis benefits from higher bioconversion efficiency and more straightforward product separation. Resting cell catalysis and microbial fermentation of flax lignan extract by the isolated β‐glucosidase production L. plantarum could be potentially applied in preparing flax lignan ingredients and fermented flaxseed. © 2024 Society of Chemical Industry. [ABSTRACT FROM AUTHOR]

To investigate the role of miR-223-3p in the modulatory effect of paeonol (Pae) on high glucose (HG)-induced endothelial cell apoptosis. HG (25 mmol/L) was used to induce cellular damage and apoptosis in the mouse cardiac microvascular endothelial cells (MCMECs). Various concentration of Pae was tested and 60 μmol/L Pae was selected for the subsequent studies. MCMECs were transfected with exogenous miR-223-3p mimics or anti-miR-223-3p inhibitors. Cell viability was assessed by MTT assay and apoptosis was quantified by flow cytometry. The expression of miR-223-3p and NLRP3 mRNA was measured using real-time quantitative RT-PCR, and protein level of NLRP3 and apoptosis-related proteins was detected by immunoblotting. Pae significantly attenuated HG-induced apoptosis of MCMECs in a concentration-dependent manner. In addition, Pae (60 µmol/L) significantly reversed HG-induced down-regulation of miR-223-3p and up-regulation of NLRP3. Pae (60 µmol/L) also significantly blocked HG-induced up-regulation of Bax and Caspase-3 as well as down-regulation of Bcl-2. Moreover, exogenous miR-223-3p mimics not only significantly attenuated HG-induced apoptosis, but also significantly suppressed NRLP-3 and pro-apoptotic proteins in the MCMECs. In contrast, transfection of exogenous miR-223-3p inhibitors into the MCMECs resulted in not only significantly increased apoptosis of the cells, but also significant suppression of NLRP3 and pro-apoptotic proteins in the cells. Pae attenuated HG-induced apoptosis of MCMECs in a concentration-dependent manner. MiR-223-3p may mediate the modulatory effects of Pae on MCMEC survival or apoptosis through targeting NLRP3 and regulating apoptosis-associated proteins. [ABSTRACT FROM AUTHOR]

Cu2O doped with atomically dispersed Rh (Rh:Cu2O) is synthesized with a wet chemical method. It shows higher activity and faradaic efficiency at lower overpotential for reduction of CO2 to C2+ products, especially C2H4, than pristine Cu2O. We found that introducing Rh promotes CO2 adsorption, *CO hydrogenation to *CHO and their coupling to O*CCHO intermediates, which contributes to enhanced catalytic performance. [ABSTRACT FROM AUTHOR]

The calculation methods of the maximum principal engineering strain,maximum principal logarithmic strain,maximum principal Green-Lagrange strain,and maximum principal Euler strain and octahedron shear strain peak under uniaxial and multiaxial loading stress condition are studied. It is found that the five damage parameters can be calculated only by outputting the deformation gradient tensor of the dangerous area in the finite element analysis. Based on the fatigue crack initiation theory and the fatigue test data of dumbbell rubber test piece,the life prediction models are established by the above five damage parameters,and the accuracy of the five life prediction models is measured by the goodness of fit value. Among them,the life prediction model with octahedron shear strain peak as damage parameter has the best fitting value. The fatigue life prediction model is established based on the fatigue crack growth theory and the crack growth test data of one-sided notch,pure shear specimen. The life prediction model with octahedral shear strain peak as damage parameter and the life prediction model based on crack growth theory were used to predict the life of the same bushing product respectively. It is found that the life prediction model with octahedral shear strain peak as damage parameter has better prediction effect,and the predicted life is near the triple scatter line of the measured life.

The tribological behaviour of articular cartilage plays a key role in joint motion; however, there is a gap in research on the effect of hyperuricemic joint fluid on cartilage friction behaviour in acute gouty arthritis. In this study, we carried out a fixed-load scratch experiment to compare the friction and wear of articular cartilage under the lubrication of gouty arthritis arthritic fluid and normal human arthritic fluid, and the results showed that the cartilage friction coefficient of patients with acute gouty arthritis was significantly larger than that of normal human beings, and that the cartilage friction coefficient decreased with the elevation of normal load and sliding speed, and the change with the sliding speed varied more differently from that of normal human beings, and that the cartilage surface wear was more severe after prolonged friction. The wear and tear of the cartilage surface is more severe after prolonged friction. Patients with gouty arthritis should reduce the sudden speed changes such as fast running and variable speed running to maintain the stability of the cartilage surface friction coefficient. [ABSTRACT FROM AUTHOR]