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1,209 results on '"Felsenberg D"'

3. A comprehensive fracture prevention strategy in older adults: The European union geriatric medicine society (EUGMS) statement

Author

Alvarez, M.N., Annweiler, C., Bernard, P.-L., Beswetherick, N., Bischoff-Ferrari, H.A., Bloch, F., Boddaert, J., Bonnefoy, M., Bousson, V., Bourdel-Marchasson, I., Capisizu, A., Che, H., Clara, J.G., Combe, B., Delignieres, D., Eklund, P., Emmelot-Vonk, M., Freiberger, E., Gauvain, J.-B., Goswami, N., Guldemond, N., Herrero, Á.C., Joël, M.-E., Jónsdóttir, A.B., Kemoun, G., Kiss, I., Kolk, H., Kowalski, M.L., Krajcík, Š., Kutsal, Y.G., Lauretani, F., Macijauskienė, J., Mellingsæter, M., Morel, J., Mourey, F., Nourashemi, F., Nyakas, C., Puisieux, F., Rambourg, P., Ramírez, A.G., Rapp, K., Rolland, Y., Ryg, J., Sahota, O., Snoeijs, S., Stephan, Y., Thomas, E., Todd, C., Treml, J., Adachi, R., Agnusdei, D., Body, J.-J., Breuil, V., Bruyère, O., Burckardt, P., Cannata-Andia, J.B., Carey, J., Chan, D.-C., Chapuis, L., Chevalley, T., Cohen-Solal, M., Dawson-Hughes, B., Dennison, E.M., Devogelaer, J.-P., Fardellone, P., Féron, J.-M., Perez, A.D., Felsenberg, D., Glueer, C., Harvey, N., Hiligsman, M., Javaid, M.K., Jörgensen, N.R., Kendler, D., Kraenzlin, M., Laroche, M., Legrand, E., Leslie, W.D., Lespessailles, E., Lewiecki, E.M., Nakamura, T., Papaioannou, A., Roux, C., Silverman, S., Henriquez, M.S., Thomas, T., Vasikaran, S., Watts, N.B., Weryha, G., Blain, H., Masud, T., Dargent-Molina, P., Martin, F.C., Rosendahl, E., van der Velde, N., Bousquet, J., Benetos, A., Cooper, C., Kanis, J.A., Reginster, J.Y., Rizzoli, R., Cortet, B., Barbagallo, M., Dreinhöfer, K., Vellas, B., Maggi, S., and Strandberg, T.

Published
2016
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6. Age-Related Declines in Lower Limb Muscle Function are Similar in Power and Endurance Athletes of Both Sexes: A Longitudinal Study of Master Athletes

Author

Ireland, A, Mittag, U, Degens, H, Felsenberg, D, Heinonen, A, Koltai, E, Korhonen, MT, McPhee, JS, Mekjavic, I, Pisot, R, Rawer, R, Radak, Z, Simunic, B, Suominen, H, Rittweger, J, Ireland, A, Mittag, U, Degens, H, Felsenberg, D, Heinonen, A, Koltai, E, Korhonen, MT, McPhee, JS, Mekjavic, I, Pisot, R, Rawer, R, Radak, Z, Simunic, B, Suominen, H, and Rittweger, J

Abstract

The age-related decline in muscle function, particularly muscle power, is associated with increased risk of important clinical outcomes. Physical activity is an important determinant of muscle function, and different types of physical activity e.g. power-based versus endurance-based exercise appear to have differential effects on muscle power. Cross-sectional studies suggest that participation in power-based exercise is associated with greater muscle power across adulthood but this has not been investigated longitudinally. We recruited eighty-nine male and female power and endurance master athletes (sprint and distance runners respectively, baseline age 35–90y). Using jumping mechanography, we measured lower limb muscle function during a vertical jump including at least two testing sessions longitudinally over 4.5 ± 2.4y. We examined effects of time, discipline (power/endurance) and sex in addition to two- and three-way interactions using linear mixed-effects models. Peak relative power, relative force and jump height, but not Esslingen Fitness Index (indicating peak power relative to sex and age-matched reference data) declined with time. Peak power, force, height and EFI were greater in power than endurance athletes. There were no sex, discipline or sex*discipline interactions with time for any variable, suggesting that changes were similar over time for athletes of both sexes and disciplines. Advantages in lower limb muscle function in power athletes were maintained with time, in line with previous cross-sectional studies. These results suggest that improvements in lower limb function in less active older individuals following power-based training persist with continued adherence, although this requires further investigation in interventional studies.

Published
2022

7. Prevalence of Physical Frailty: Results from the DO-HEALTH Study

Author

Gagesch, Michael; https://orcid.org/0000-0003-3089-5768, Chocano-Bedoya, P O, Abderhalden, L A, Freystaetter, Gregor, Sadlon, Angélique; https://orcid.org/0000-0002-9316-4113, Kanis, J A, Kressig, R W, Guyonnet, S, DaSilva, J A P, Felsenberg, D, Rizzoli, R; https://orcid.org/0000-0002-1537-422X, Blauth, Michael, Orav, E John, Egli, Adrian; https://orcid.org/0000-0002-3564-8603, Bischoff-Ferrari, H A; https://orcid.org/0000-0002-4554-658X, Gagesch, Michael; https://orcid.org/0000-0003-3089-5768, Chocano-Bedoya, P O, Abderhalden, L A, Freystaetter, Gregor, Sadlon, Angélique; https://orcid.org/0000-0002-9316-4113, Kanis, J A, Kressig, R W, Guyonnet, S, DaSilva, J A P, Felsenberg, D, Rizzoli, R; https://orcid.org/0000-0002-1537-422X, Blauth, Michael, Orav, E John, Egli, Adrian; https://orcid.org/0000-0002-3564-8603, and Bischoff-Ferrari, H A; https://orcid.org/0000-0002-4554-658X

Abstract

Background: Frailty is a geriatric syndrome associated with multiple negative health outcomes. However, its prevalence varies by population and instrument used. We investigated frailty and pre-frailty prevalence by 5 instruments in community-dwelling older adults enrolled to a randomized-controlled trial in 5 European countries. METHODS: Cross-sectional baseline analysis in 2,144 DO-HEALTH participants recruited from Switzerland, Austria, France, Germany, and Portugal with complete data for frailty. Frailty status was assessed by the Physical Frailty Phenotype [PFP], SOF-Frailty Index [SOF-FI], FRAIL-Scale, SHARE-Frailty Instrument [SHARE-FI], and a modified SHARE-FI, and compared by country, age, and gender. Logistic regression was used to determine relevant factors associated with frailty and pre-frailty. RESULTS: Mean age was 74.9 (±4.4) years, 61.6% were women. Based on the PFP, overall frailty and pre-frailty prevalence was 3.0% and 43.0%. By country, frailty prevalence was highest in Portugal (13.7%) and lowest in Austria (0%), and pre-frailty prevalence was highest in Portugal (57.3%) and lowest in Germany (37.1%). By instrument and overall, frailty and pre-frailty prevalence was highest based on SHARE-FI (7.0% / 43.7%) and lowest based on SOF-FI (1.0% / 25.9%). Frailty associated factors were residing in Coimbra (Portugal) [OR 12.0, CI 5.30-27.21], age above 75 years [OR 2.0, CI 1.17-3.45], and female gender [OR 2.8, CI 1.48-5.44]. The same three factors predicted pre-frailty. CONCLUSIONS: Among relatively healthy adults age 70 and older enroled to DO-HEALTH, prevalence of frailty and pre-frailty differed significantly by instrument, country, gender, and age. Among instruments, the highest prevalence of frailty and pre-frailty was documented by the SHARE-FI and the lowest by the SOF-FI.

Published
2022

9. Vertebral Scheuermann’s disease in Europe: prevalence, geographic variation and radiological correlates in men and women aged 50 and over

Author

Armbrecht, G., Felsenberg, D., Ganswindt, M., Lunt, M., Kaptoge, S. K., Abendroth, K., Aroso, A., Banzer, D., Bhalla, A. K., Dequeker, J., Eastell, R., Hoszowski, K., Lyritis, G., Delmas, P. D., Masaryk, P., Miazgowski, T., Cannata, J., Nuti, R., Oei, L., Poor, G., Redlund-Johnell, I., Reid, D. M., Reisinger, W., Schatz, H., Todd, C. J., Woolf, A. D., Javaid, K., Rivadeneira, F., Silman, A. J., Cooper, C., O’Neill, T. W., Reeve, J., and On behalf of the European Vertebral Osteoporosis Study (EVOS) and European Prospective Osteoporosis Study (EPOS) Groups

Published
2015
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46. Greater maintenance of bone mineral content in male than female athletes, and in sprinting and jumping than endurance athletes: a longitudinal study of bone strength in elite masters athletes

Author

Ireland, A, Mittag, U, Degens, H, Felsenberg, D, Ferretti, JL, Heinonen, A, Koltai, E, Korhonen, MT, Mcphee, JS, Mekjavic, I, Piasecki, J, Pisot, R, Radak, Z, Simunic, B, Suominen, H, Wilks, DC, Winwood, K, Rittweger, J, Ferretti, J, Korhonen, M, Mcphee, J, and Wilks, D

Abstract

Summary: We investigated longitudinal changes in tibia bone strength in master power (jumping and sprinting) and endurance (distance) athletes of both sexes. Bone mass but not cross‐sectional moment of inertia was better maintained in power than endurance athletes over time, particularly in men and independent of changes in performance.\ud \ud Objective: Assessment of effects of sex and athletic discipline (lower limb power events e.g. sprint running and jumping versus endurance running events) on longitudinal changes in bone strength in masters athletes.\ud \ud Methods: We examined tibia and fibula bone properties at distal (4% distal‐proximal tibia length) and proximal (66% length) sites using peripheral quantitative computed tomography (pQCT) in seventy‐one track and field masters athletes (30 male, 41 female, age at baseline 57.0±12.2y) in a longitudinal cohort study that included at least two testing sessions over a mean period of 4.2±3.1y. Effects of time, as well as time*sex and time*discipline interactions on bone parameters and calf muscle cross‐sectional area (CSA) were examined.\ud \ud Results: Effects of time were sex and discipline‐dependent, even following adjustment for enrolment age, sex, and changes in muscle CSA and athletic performance. Male sex and participation in power events was associated with better maintenance of tibia bone mineral content (BMC, an indicator of bone compressive strength) at 4% and 66% sites. In contrast, there was no strong evidence of sex or discipline effects on cross‐sectional moment of inertia (CSMI, an indicator of bone bending and torsional strength – P > 0.3 for interactions). Similar sex and discipline‐specific changes were also observed in the fibula.\ud \ud Conclusions: Results suggest that male athletes and those participating in lower limb power‐based rather than endurance‐based disciplines have better maintenance of bone compressive but not bending and torsional strength.

Published
2020

47. Whom to treat? The contribution of vertebral X-rays to risk-based algorithms for fracture prediction. Results from the European Prospective Osteoporosis Study

Author

Kaptoge, S., Armbrecht, G., Felsenberg, D., Lunt, M., Weber, K., Boonen, S., Jajic, I., Stepan, J. J., Banzer, D., Reisinger, W., Janott, J., Kragl, G., Scheidt-Nave, C., Felsch, B., Matthis, C., Raspe, H. H., Lyritis, G., Póor, G, Nuti, R., Miazgowski, T., Hoszowski, K., Armas, J. Bruges, Vaz, A. Lopes, Benevolenskaya, L. I., Masaryk, P., Cannata, J. B., Johnell, O., Reid, D. M., Bhalla, A., Woolf, A. D., Todd, C. J., Cooper, C., Eastell, R., Kanis, J. A., O’Neill, T. W., Silman, A. J., and Reeve, J.

Published
2006
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49. Effects of 8 weeks of bed rest with or without resistance exercise intervention on the volume of the muscle tissue and the adipose tissues of the thigh

Author

Ogawa, M, Belavy, D, Yoshiko, A, Armbrecht, G, Miokovic, T, Felsenberg, D, Akima, H, Ogawa, M, Belavy, D, Yoshiko, A, Armbrecht, G, Miokovic, T, Felsenberg, D, and Akima, H

Abstract

The present study aims to investigate the effects of 8 weeks of bed rest, with or without resistance exercise intervention, on the volumes of muscle tissue and the intramuscular, intermuscular, and subcutaneous adipose tissues of the thigh. Twenty men were included, who were randomly assigned in three groups: resistance exercises group (RE group), resistance exercises with whole‐body vibration group (VRE group), and nonexercise control group (CTR group). The RE and VRE groups performed resistance exercises during 8 weeks of bed rest (3 days per week). Additionally, consecutive axial magnetic resonance images were obtained before and after the bed rest. Using these images, the volumes of the muscle tissue and the intramuscular adipose tissue, intermuscular adipose tissue, and subcutaneous adipose tissue of the thigh were evaluated. No significant time‐by‐group interaction was observed the volumes of the muscle tissue and the intramuscular adipose tissue, intermuscular adipose tissue, and subcutaneous adipose tissue between the RE and VRE groups. Furthermore, the RE and VRE groups were pooled as the resistance exercise intervention group (TR group), wherein their thigh muscle tissue volume was observed to be maintained after the bed rest. However, that of the CTR group significantly decreased. Regarding the thigh intramuscular adipose tissue and intermuscular adipose tissue volumes, no significant difference was observed among the CTR and TR groups. Although subcutaneous adipose tissue volume in the CTR group significantly increased after the bed rest, no changes were observed in that of the TR group. Therefore, the results of the present study suggested that within the 8 weeks of bed rest, adipose tissue adaptation differs depending on the location.

Published
2020

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