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127 results on '"Felix Franke"'

1. Suppression without inhibition: how retinal computation contributes to saccadic suppression

Author

Saad Idrees, Matthias-Philipp Baumann, Maria M. Korympidou, Timm Schubert, Alexandra Kling, Katrin Franke, Ziad M. Hafed, Felix Franke, and Thomas A. Münch

Subjects
Biology (General), QH301-705.5
Abstract

Sequential light stimulation reduces the sensitivity of retinal ganglion cells via three different mechanisms which differentially affect ON and OFF cells.

Published
2022
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2. Perceptual saccadic suppression starts in the retina

Author

Saad Idrees, Matthias P. Baumann, Felix Franke, Thomas A. Münch, and Ziad M. Hafed

Subjects
Science
Abstract

Saccadic suppression is frequently attributed to active suppressive signals derived from eye movement commands. Here, the authors show that visual-only mechanisms starting in the retina can account for perceptual saccadic suppression properties without the need for motor-based suppression commands.

Published
2020
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3. 26th Annual Computational Neuroscience Meeting (CNS*2017): Part 2

Author

Leonid L. Rubchinsky, Sungwoo Ahn, Wouter Klijn, Ben Cumming, Stuart Yates, Vasileios Karakasis, Alexander Peyser, Marmaduke Woodman, Sandra Diaz-Pier, James Deraeve, Eliana Vassena, William Alexander, David Beeman, Pawel Kudela, Dana Boatman-Reich, William S. Anderson, Niceto R. Luque, Francisco Naveros, Richard R. Carrillo, Eduardo Ros, Angelo Arleo, Jacob Huth, Koki Ichinose, Jihoon Park, Yuji Kawai, Junichi Suzuki, Hiroki Mori, Minoru Asada, Sorinel A. Oprisan, Austin I. Dave, Tahereh Babaie, Peter Robinson, Alejandro Tabas, Martin Andermann, André Rupp, Emili Balaguer-Ballester, Henrik Lindén, Rasmus K. Christensen, Mari Nakamura, Tania R. Barkat, Zach Tosi, John Beggs, Davide Lonardoni, Fabio Boi, Stefano Di Marco, Alessandro Maccione, Luca Berdondini, Joanna Jędrzejewska-Szmek, Daniel B. Dorman, Kim T. Blackwell, Christoph Bauermeister, Hanna Keren, Jochen Braun, João V. Dornas, Eirini Mavritsaki, Silvio Aldrovandi, Emma Bridger, Sukbin Lim, Nicolas Brunel, Anatoly Buchin, Clifford Charles Kerr, Anton Chizhov, Gilles Huberfeld, Richard Miles, Boris Gutkin, Martin J. Spencer, Hamish Meffin, David B. Grayden, Anthony N. Burkitt, Catherine E. Davey, Liangyu Tao, Vineet Tiruvadi, Rehman Ali, Helen Mayberg, Robert Butera, Cengiz Gunay, Damon Lamb, Ronald L. Calabrese, Anca Doloc-Mihu, Víctor J. López-Madrona, Fernanda S. Matias, Ernesto Pereda, Claudio R. Mirasso, Santiago Canals, Alice Geminiani, Alessandra Pedrocchi, Egidio D’Angelo, Claudia Casellato, Ankur Chauhan, Karthik Soman, V. Srinivasa Chakravarthy, Vignayanandam R. Muddapu, Chao-Chun Chuang, Nan-yow Chen, Mehdi Bayati, Jan Melchior, Laurenz Wiskott, Amir Hossein Azizi, Kamran Diba, Sen Cheng, Elena Y. Smirnova, Elena G. Yakimova, Anton V. Chizhov, Nan-Yow Chen, Chi-Tin Shih, Dorian Florescu, Daniel Coca, Julie Courtiol, Viktor K. Jirsa, Roberto J. M. Covolan, Bartosz Teleńczuk, Richard Kempter, Gabriel Curio, Alain Destexhe, Jessica Parker, Alexander N. Klishko, Boris I. Prilutsky, Gennady Cymbalyuk, Felix Franke, Andreas Hierlemann, Rava Azeredo da Silveira, Stefano Casali, Stefano Masoli, Martina Rizza, Martina Francesca Rizza, Yinming Sun, Willy Wong, Faranak Farzan, Daniel M. Blumberger, Zafiris J. Daskalakis, Svitlana Popovych, Shivakumar Viswanathan, Nils Rosjat, Christian Grefkes, Silvia Daun, Damiano Gentiletti, Piotr Suffczynski, Vadym Gnatkovski, Marco De Curtis, Hyeonsu Lee, Se-Bum Paik, Woochul Choi, Jaeson Jang, Youngjin Park, Jun Ho Song, Min Song, Vicente Pallarés, Matthieu Gilson, Simone Kühn, Andrea Insabato, Gustavo Deco, Katharina Glomb, Adrián Ponce-Alvarez, Petra Ritter, Adria Tauste Campo, Alexander Thiele, Farah Deeba, P. A. Robinson, Sacha J. van Albada, Andrew Rowley, Michael Hopkins, Maximilian Schmidt, Alan B. Stokes, David R. Lester, Steve Furber, Markus Diesmann, Alessandro Barri, Martin T. Wiechert, David A. DiGregorio, Alexander G. Dimitrov, Catalina Vich, Rune W. Berg, Antoni Guillamon, Susanne Ditlevsen, Romain D. Cazé, Benoît Girard, Stéphane Doncieux, Nicolas Doyon, Frank Boahen, Patrick Desrosiers, Edward Laurence, Louis J. Dubé, Russo Eleonora, Daniel Durstewitz, Dominik Schmidt, Tuomo Mäki-Marttunen, Florian Krull, Francesco Bettella, Christoph Metzner, Anna Devor, Srdjan Djurovic, Anders M. Dale, Ole A. Andreassen, Gaute T. Einevoll, Solveig Næss, Torbjørn V. Ness, Geir Halnes, Eric Halgren, Klas H. Pettersen, Marte J. Sætra, Espen Hagen, Alina Schiffer, Axel Grzymisch, Malte Persike, Udo Ernst, Daniel Harnack, Udo A. Ernst, Nergis Tomen, Stefano Zucca, Valentina Pasquale, Giuseppe Pica, Manuel Molano-Mazón, Michela Chiappalone, Stefano Panzeri, Tommaso Fellin, Kelvin S. Oie, David L. Boothe, Joshua C. Crone, Alfred B. Yu, Melvin A. Felton, Isma Zulfiqar, Michelle Moerel, Peter De Weerd, Elia Formisano, Kelvin Oie, Piotr Franaszczuk, Roland Diggelmann, Michele Fiscella, Domenico Guarino, Jan Antolík, Andrew P. Davison, Yves Frègnac, Benjamin Xavier Etienne, Flavio Frohlich, Jérémie Lefebvre, Encarni Marcos, Maurizio Mattia, Aldo Genovesio, Leonid A. Fedorov, Tjeerd M.H. Dijkstra, Louisa Sting, Howard Hock, Martin A. Giese, Laure Buhry, Clément Langlet, Francesco Giovannini, Christophe Verbist, Stefano Salvadé, Michele Giugliano, James A. Henderson, Hendrik Wernecke, Bulcsú Sándor, Claudius Gros, Nicole Voges, Paulina Dabrovska, Alexa Riehle, Thomas Brochier, Sonja Grün, Yifan Gu, Pulin Gong, Grégory Dumont, Nikita A. Novikov, Boris S. Gutkin, Parul Tewatia, Olivia Eriksson, Andrei Kramer, Joao Santos, Alexandra Jauhiainen, Jeanette H. Kotaleski, Jovana J. Belić, Arvind Kumar, Jeanette Hellgren Kotaleski, Masanori Shimono, Naomichi Hatano, Subutai Ahmad, Yuwei Cui, Jeff Hawkins, Johanna Senk, Karolína Korvasová, Tom Tetzlaff, Moritz Helias, Tobias Kühn, Michael Denker, PierGianLuca Mana, David Dahmen, Jannis Schuecker, Sven Goedeke, Christian Keup, Katja Heuer, Rembrandt Bakker, Paul Tiesinga, Roberto Toro, Wei Qin, Alex Hadjinicolaou, Michael R. Ibbotson, Tatiana Kameneva, William W. Lytton, Lealem Mulugeta, Andrew Drach, Jerry G. Myers, Marc Horner, Rajanikanth Vadigepalli, Tina Morrison, Marlei Walton, Martin Steele, C. Anthony Hunt, Nicoladie Tam, Rodrigo Amaducci, Carlos Muñiz, Manuel Reyes-Sánchez, Francisco B. Rodríguez, Pablo Varona, Joseph T. Cronin, Matthias H. Hennig, Elisabetta Iavarone, Jane Yi, Ying Shi, Bas-Jan Zandt, Werner Van Geit, Christian Rössert, Henry Markram, Sean Hill, Christian O’Reilly, Rodrigo Perin, Huanxiang Lu, Alexander Bryson, Michal Hadrava, Jaroslav Hlinka, Ryosuke Hosaka, Mark Olenik, Conor Houghton, Nicolangelo Iannella, Thomas Launey, Rebecca Kotsakidis, Jaymar Soriano, Takatomi Kubo, Takao Inoue, Hiroyuki Kida, Toshitaka Yamakawa, Michiyasu Suzuki, Kazushi Ikeda, Samira Abbasi, Amber E. Hudson, Detlef H. Heck, Dieter Jaeger, Joel Lee, Skirmantas Janušonis, Maria Luisa Saggio, Andreas Spiegler, William C. Stacey, Christophe Bernard, Davide Lillo, Spase Petkoski, Mark Drakesmith, Derek K. Jones, Ali Sadegh Zadeh, Chandra Kambhampati, Jan Karbowski, Zeynep Gokcen Kaya, Yair Lakretz, Alessandro Treves, Lily W. Li, Joseph Lizier, Cliff C. Kerr, Timothée Masquelier, Saeed Reza Kheradpisheh, Hojeong Kim, Chang Sub Kim, Julia A. Marakshina, Alexander V. Vartanov, Anastasia A. Neklyudova, Stanislav A. Kozlovskiy, Andrey A. Kiselnikov, Kanako Taniguchi, Katsunori Kitano, Oliver Schmitt, Felix Lessmann, Sebastian Schwanke, Peter Eipert, Jennifer Meinhardt, Julia Beier, Kanar Kadir, Adrian Karnitzki, Linda Sellner, Ann-Christin Klünker, Lena Kuch, Frauke Ruß, Jörg Jenssen, Andreas Wree, Paula Sanz-Leon, Stuart A. Knock, Shih-Cheng Chien, Burkhard Maess, Thomas R. Knösche, Charles C. Cohen, Marko A. Popovic, Jan Klooster, Maarten H.P. Kole, Erik A. Roberts, Nancy J. Kopell, Daniel Kepple, Hamza Giaffar, Dima Rinberg, Alex Koulakov, Caroline Garcia Forlim, Leonie Klock, Johanna Bächle, Laura Stoll, Patrick Giemsa, Marie Fuchs, Nikola Schoofs, Christiane Montag, Jürgen Gallinat, Ray X. Lee, Greg J. Stephens, Bernd Kuhn, Luiz Tauffer, Philippe Isope, Katsuma Inoue, Yoshiyuki Ohmura, Shogo Yonekura, Yasuo Kuniyoshi, Hyun Jae Jang, Jeehyun Kwag, Marc de Kamps, Yi Ming Lai, Filipa dos Santos, K. P. Lam, Peter Andras, Julia Imperatore, Jessica Helms, Tamas Tompa, Antonieta Lavin, Felicity H. Inkpen, Michael C. Ashby, Nathan F. Lepora, Aaron R. Shifman, John E. Lewis, Zhong Zhang, Yeqian Feng, Christian Tetzlaff, Tomas Kulvicius, Yinyun Li, Rodrigo F. O. Pena, Davide Bernardi, Antonio C. Roque, Benjamin Lindner, Sebastian Vellmer, Ausra Saudargiene, Tiina Maninen, Riikka Havela, Marja-Leena Linne, Arthur Powanwe, Andre Longtin, Jesús A. Garrido, Joe W. Graham, Salvador Dura-Bernal, Sergio L. Angulo, Samuel A. Neymotin, and Srdjan D. Antic

Subjects
Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurophysiology and neuropsychology, QP351-495
Published
2017
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4. Combination of High-density Microelectrode Array and Patch Clamp Recordings to Enable Studies of Multisynaptic Integration

Author

David Jäckel, Douglas J. Bakkum, Thomas L. Russell, Jan Müller, Milos Radivojevic, Urs Frey, Felix Franke, and Andreas Hierlemann

Subjects
Medicine, Science
Abstract

Abstract We present a novel, all-electric approach to record and to precisely control the activity of tens of individual presynaptic neurons. The method allows for parallel mapping of the efficacy of multiple synapses and of the resulting dynamics of postsynaptic neurons in a cortical culture. For the measurements, we combine an extracellular high-density microelectrode array, featuring 11’000 electrodes for extracellular recording and stimulation, with intracellular patch-clamp recording. We are able to identify the contributions of individual presynaptic neurons - including inhibitory and excitatory synaptic inputs - to postsynaptic potentials, which enables us to study dendritic integration. Since the electrical stimuli can be controlled at microsecond resolution, our method enables to evoke action potentials at tens of presynaptic cells in precisely orchestrated sequences of high reliability and minimum jitter. We demonstrate the potential of this method by evoking short- and long-term synaptic plasticity through manipulation of multiple synaptic inputs to a specific neuron.

Published
2017
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5. Technologies to Study Action Potential Propagation With a Focus on HD-MEAs

Author

Vishalini Emmenegger, Marie Engelene J. Obien, Felix Franke, and Andreas Hierlemann

Subjects
axon, action potential propagation, patch-clamp technique, genetically encoded voltage indicators, high-density microelectrode arrays, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

Axons convey information in neuronal circuits via reliable conduction of action potentials (APs) from the axon initial segment (AIS) to the presynaptic terminals. Recent experimental findings increasingly evidence that the axonal function is not limited to the simple transmission of APs. Advances in subcellular-resolution recording techniques have shown that axons display activity-dependent modulation in spike shape and conduction velocity, which influence synaptic strength and latency. We briefly review here, how recent methodological developments facilitate the understanding of the axon physiology. We included the three most common methods, i.e., genetically encoded voltage imaging (GEVI), subcellular patch-clamp and high-density microelectrode arrays (HD-MEAs). We then describe the potential of using HD-MEAs in studying axonal physiology in more detail. Due to their robustness, amenability to high-throughput and high spatiotemporal resolution, HD-MEAs can provide a direct functional electrical readout of single cells and cellular ensembles at subcellular resolution. HD-MEAs can, therefore, be employed in investigating axonal pathologies, the effects of large-scale genomic interventions (e.g., with RNAi or CRISPR) or in compound screenings. A combination of extracellular microelectrode arrays (MEAs), intracellular microelectrodes and optical imaging may potentially reveal yet unexplored repertoires of axonal functions.

Published
2019
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6. Optimal Electrode Size for Multi-Scale Extracellular-Potential Recording From Neuronal Assemblies

Author

Vijay Viswam, Marie Engelene J. Obien, Felix Franke, Urs Frey, and Andreas Hierlemann

Subjects
electrode size, impedance, microelectrode array, extracellular recording, extracellular action potential, local field potential, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

Advances in microfabrication technology have enabled the production of devices containing arrays of thousands of closely spaced recording electrodes, which afford subcellular resolution of electrical signals in neurons and neuronal networks. Rationalizing the electrode size and configuration in such arrays demands consideration of application-specific requirements and inherent features of the electrodes. Tradeoffs among size, spatial density, sensitivity, noise, attenuation, and other factors are inevitable. Although recording extracellular signals from neurons with planar metal electrodes is fairly well established, the effects of the electrode characteristics on the quality and utility of recorded signals, especially for small, densely packed electrodes, have yet to be fully characterized. Here, we present a combined experimental and computational approach to elucidating how electrode size, and size-dependent parameters, such as impedance, baseline noise, and transmission characteristics, influence recorded neuronal signals. Using arrays containing platinum electrodes of different sizes, we experimentally evaluated the electrode performance in the recording of local field potentials (LFPs) and extracellular action potentials (EAPs) from the following cell preparations: acute brain slices, dissociated cell cultures, and organotypic slice cultures. Moreover, we simulated the potential spatial decay of point-current sources to investigate signal averaging using known signal sources. We demonstrated that the noise and signal attenuation depend more on the electrode impedance than on electrode size, per se, especially for electrodes

Published
2019
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7. Medullary Respiratory Circuit Is Reorganized by a Seasonally-Induced Program in Preparation for Hibernation

Author

Thomas L. Russell, Jichang Zhang, Michal Okoniewski, Felix Franke, Sandrine Bichet, and Andreas Hierlemann

Subjects
microelectrode array, electrophysiology, hibernation, respiratory rhythms, ventral respiratory group, medulla, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

Deep hibernators go through several cycles of profound drops in body temperature during the winter season, with core temperatures sometimes reaching near freezing. Yet unlike non-hibernating mammals, they can sustain breathing rhythms. The physiological processes that make this possible are still not understood. In this study, we focused on the medullary Ventral Respiratory Column of a facultative hibernator, the Syrian hamster. Using shortened day-lengths, we induced a “winter-adapted” physiological state, which is a prerequisite for hibernation. When recording electrophysiological signals from acute slices in the winter-adapted pre-Bötzinger complex (preBötC), spike trains showed higher spike rates, amplitudes, complexity, as well as higher temperature sensitivity, suggesting an increase in connectivity and/or synaptic strength during the winter season. We further examined action potential waveforms and found that the depolarization integral, as measured by the area under the curve, is selectively enhanced in winter-adapted animals. This suggests that a shift in the ion handling kinetics is also being induced by the winter-adaptation program. RNA sequencing of respiratory pre-motor neurons, followed by gene set enrichment analysis, revealed differential regulation and splicing in structural, synaptic, and ion handling genes. Splice junction analysis suggested that differential exon usage is occurring in a select subset of ion handling subunits (ATP1A3, KCNC3, SCN1B), and synaptic structure genes (SNCB, SNCG, RAB3A). Our findings show that the hamster respiratory center undergoes a seasonally-cued alteration in electrophysiological properties, likely protecting against respiratory failure at low temperatures.

Published
2019
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8. Tracking individual action potentials throughout mammalian axonal arbors

Author

Milos Radivojevic, Felix Franke, Michael Altermatt, Jan Müller, Andreas Hierlemann, and Douglas J Bakkum

Subjects
axonal physiology, HD-MEA, electrode-neuron interface, Medicine, Science, Biology (General), QH301-705.5
Abstract

Axons are neuronal processes specialized for conduction of action potentials (APs). The timing and temporal precision of APs when they reach each of the synapses are fundamentally important for information processing in the brain. Due to small diameters of axons, direct recording of single AP transmission is challenging. Consequently, most knowledge about axonal conductance derives from modeling studies or indirect measurements. We demonstrate a method to noninvasively and directly record individual APs propagating along millimeter-length axonal arbors in cortical cultures with hundreds of microelectrodes at microsecond temporal resolution. We find that cortical axons conduct single APs with high temporal precision (~100 µs arrival time jitter per mm length) and reliability: in more than 8,000,000 recorded APs, we did not observe any conduction or branch-point failures. Upon high-frequency stimulation at 100 Hz, successive became slower, and their arrival time precision decreased by 20% and 12% for the 100th AP, respectively.

Published
2017
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14. Technologiekombinationen zur Identifikation und Lokalisierung in der Produktion

Author

Philipp Wilsky, Felix Franke, Daniel Fischer, Franziska Gassenbauer, and Ralph Riedel

Subjects
Strategy and Management, General Engineering, Management Science and Operations Research
Abstract

Digitale Technologien erfahren in der Produktion ein stetiges Wachstum. Für den Erfolg von digitalen Anwendungen ist die produktionsnahe Datenerfassung und -aufbereitung entscheidend. Hierfür sind Technologien zur automatischen Identifikation (z. B. RFID) sowie zur Indoor-Lokalisierung (z. B. BLE) gut geeignet. In der Planung dieser Systeme ergeben sich jedoch Fallstricke: Wenn Know-how über die technologischen Einsatzmöglichkeiten fehlt, kann es durch die unreflektierte Kombination von Technologien zu Störungen und Effizienzverlusten kommen. Der Beitrag stellt daher eine Methode zur Analyse von Technologiekombination vor, die eine zielgerichtete Konzeption im Hinblick auf die Problemanalyse und Lösungsauswahl beim Einsatz mehrerer Technologien ermöglicht.

Published
2022

17. Parallel reconstruction of the excitatory and inhibitory inputs received by single neurons reveals the synaptic basis of recurrent spiking

Author

Julian Bartram, Felix Franke, Sreedhar Saseendran Kumar, Alessio Paolo Buccino, Xiaohan Xue, Tobias Gänswein, Manuel Schröter, Taehoon Kim, Krishna Chaitanya Kasuba, and Andreas Hierlemann

Abstract

Self-sustained recurrent activity in cortical networks is thought to be important for multiple crucial processes, including circuit development and homeostasis. Yet, the precise relationship between the synaptic input patterns and the spiking output of individual neurons remains largely unresolved. Here, we developed, validated and applied a novel in vitro experimental platform and analytical procedures that provide – for individual neurons – simultaneous excitatory and inhibitory synaptic activity estimates during recurrent network activity. Our approach combines whole-network high-density microelectrode array (HD-MEA) recordings from rat neuronal cultures with patch clamping and enables a comprehensive mapping and characterization of active incoming connections to single postsynaptic neurons. We found that, during network states with excitation(E)-inhibition(I) balance, postsynaptic spiking coincided precisely with the maxima of fast fluctuations in the input E/I ratio. These spike-associated E/I ratio escalations were largely due to a rapid bidirectional change in synaptic inhibition that was modulated by the network-activity level. Our approach also uncovered the underlying circuit architecture and we show that individual neurons received a few key inhibitory connections – often from special hub neurons – that were instrumental in controlling postsynaptic spiking. Balanced network theory predicts dynamical regimes governed by small and rapid input fluctuation and featuring a fast neuronal responsiveness. Our findings – obtained in self-organized neuronal cultures – suggest that the emergence of these favorable regimes and associated network architectures is an inherent property of cortical networks in general.

Published
2023

21. Gaia Early Data Release 3 The Gaia Catalogue of Nearby Stars

Author

Zoltan Balog, G. Tauran, Vincenzo Ripepi, Gerry Gilmore, M. Barros, Łukasz Wyrzykowski, Alberto Cellino, E. Poggio, P. Gavras, Simchon Faigler, Marc Audard, C. Nicolas, M. Vaillant, A. Mora, Paolo Tanga, Silvio Leccia, Despina Hatzidimitriou, A. Dapergolas, Eva Sciacca, Alberto Krone-Martins, N. Cheek, M. Hauser, Ulrike Heiter, S. Managau, L. Rohrbasser, Mathias Schultheis, E. Utrilla, Minia Manteiga, Marcella Marconi, Xavier Luri, F. De Angeli, Shay Zucker, Paolo Giacobbe, J. Juaristi Campillo, H. I. Siddiqui, J. Torra, F. X. Pineau, Roy Gomel, Thierry Morel, T. Cornez, Eric Gosset, Mario Gai, Jose M Hernandez, G. Giuffrida, A. de Torres, Laszlo Szabados, S. Ragaini, E. van Dillen, D. Semeux, Leanne P. Guy, R. Drimmel, L. M. Sarro, S. Voutsinas, Johannes Sahlmann, Damien Ségransan, S. Liao, Derek W. Morris, Jan Rybizki, André Moitinho, T. Roegiers, Bengt Edvardsson, Tristan Cantat-Gaudin, Martin Altmann, C. Turon, Laurent Chemin, K. Janßen, D. Garabato, Alejandra Recio-Blanco, Michał Pawlak, Lorenzo Rimoldini, Sergei A. Klioner, F. Torra, Carine Babusiaux, Alfred Castro-Ginard, G. Plum, Mariateresa Crosta, Iain A. Steele, A. Yoldas, Alex Lobel, J.-L. Bassilana, Harry Enke, Rosanna Sordo, Francesca Fragkoudi, F. De Luise, M. Bernet, Alessandro Sozzetti, M. Kontizas, Roberto Molinaro, C. Diener, S. Regibo, D. Barbato, T. Pauwels, R. E. de Souza, C. Fabricius, D. Souami, L. Martin Polo, M. Ramos-Lerate, Douglas J. Marshall, A. G. Butkevich, P. Madrero Pardo, P. Re Fiorentin, J. F. Le Campion, Jérôme Berthier, N. Tonello, Ummi Abbas, Y. Lebreton, M. Biermann, D. Munoz, N. Brouillet, David Teyssier, O. Vanel, P. A. Palicio, A. Jean-Antoine Piccolo, A. F. Lanza, Jesus Salgado, E. del Pozo, Antti Penttilä, R. Geyer, Ramachrisna Teixeira, L. Chaoul, Mike Smith, Rossella Cancelliere, J. M. Martín-Fleitas, D. Baines, M. Romero-Gómez, E. Anglada Varela, E. Livanou, X. Peñalosa Esteller, S. Diakite, Alberto Vecchiato, Thomas Wevers, Daniel Hestroffer, Sebastian L. Hidalgo, M. David, Angela Bragaglia, J. De Ridder, Mark Taylor, Roberto Morbidelli, A. Sagristà Sellés, Nigel Hambly, Arnaud Siebert, R. L. Smart, P. Burgess, Y. Le Fustec, Alessandro Bressan, H. Steidelmüller, Alberto Riva, H. E. Huckle, Morgan Fouesneau, N. Bauchet, P. Osborne, S. Marinoni, Krzysztof A. Rybicki, A. Masip, Laia Casamiquela, R. Messineo, A. Garofalo, Antonella Vallenari, R. Mor, Sahar Shahaf, P. de Laverny, G. Sadowski, Peter G. Jonker, A. Kochoska, F. Taris, A. F. Mulone, M. Ajaj, C. Ducourant, T. A. Lister, F. A. Jansen, Ruth Carballo, J. M. Carrasco, Tatiana Muraveva, W. van Reeven, P. Sartoretti, Jordi Portell, Andreas Korn, E. Salguero, Ana Ulla, P. Di Matteo, Coryn A. L. Bailer-Jones, J. Bakker, F. Riclet, G. Altavilla, Ulrich Bastian, P. Esquej, R. Buzzi, M. Segol, A. C. Lanzafame, L. Balaguer-Núñez, Beatrice Bucciarelli, C. Panem, E. Balbinot, T. Carlucci, Davide Massari, P. de Teodoro, Sébastien Lambert, M. I. Carnerero, Amina Helmi, F. Solitro, C. Robin, Carlos Dafonte, Tsevi Mazeh, A. Panahi, C. Fabre, Sergi Blanco-Cuaresma, Deborah Busonero, Maroussia Roelens, O. Marchal, Tomaz Zwitter, B. Holl, G. Holland, William Thuillot, Michael Davidson, E. Licata, Michele Bellazzini, Teresa Antoja, E. Szegedi-Elek, Francesca Figueras, Eric Slezak, Sergio Messina, N. Samaras, E. Poujoulet, Mark Cropper, A. Burlacu, R. Blomme, Elmé Breedt, Annie C. Robin, H. E. Delgado, Z. Kostrzewa-Rutkowska, Georges Kordopatis, Conny Aerts, L. Noval, Daniel Michalik, P. J. Richards, L. Karbevska, Grigori Fedorets, Maria Süveges, F. Crifo, J. Guiraud, D. Eappachen, K. Kruszyńska, Gisella Clementini, P. Yvard, Carme Jordi, L. Bramante, G. Busso, P. David, E. Fraile, Ugo Becciani, A. Lorca, Sanjeev Khanna, Alex Bombrun, Isabella Pagano, C. Dolding, A. M. Piersimoni, Paolo Montegriffo, A. Abreu Aramburu, Anthony G. A. Brown, Simon Hodgkin, Ennio Poretti, M. Fabrizio, I. Gonzalez-Santamaria, N. A. Walton, P. Panuzzo, Benoit Carry, Raphael Guerra, J. J. González-Vidal, T. Lebzelter, Nami Mowlavi, C. Barache, M. M. S. Marcos Santos, S. Cowell, Marco Castellani, J. J. Aguado, N. R. Millar, A. Baudesson-Stella, N. Leclerc, S. Bartolomé, J. Álvarez Cid-Fuentes, F. van Leeuwen, S. Bouquillon, Uwe Lammers, D. W. Evans, L. Eyer, M. van Leeuwen, A. Guerrier, J. González-Núñez, H. E. P. Lindstrøm, Miguel García-Torres, Ilaria Musella, L. Palaversa, W. Roux, W. Löffler, J.-B. Delisle, Dimitri Pourbaix, Timo Prusti, J. Osinde, M. Riello, G. Orrù, C. Crowley, Alessandra Mastrobuono-Battisti, Hector Canovas, D. L. Harrison, Y. Lasne, E. F. del Peloso, Laurent Galluccio, N. Hładczuk, T. Boch, Martin A. Barstow, László Molnár, Aldo Dell'Oro, C. Pagani, Krzysztof Nienartowicz, Stefano Bertone, Patrick Charlot, Eduard Masana, Elisabetta Caffau, N. Robichon, Luciana Bianchi, Federica Spoto, Felix Franke, J. L. Halbwachs, R. Gutiérrez-Sánchez, L. Pulone, Yassine Damerdji, Frédéric Arenou, Richard I. Anderson, Elena Pancino, David Hobbs, P. Castro Sampol, Yves Fremat, Pierre Kervella, C. Zurbach, Sofia Randich, Robert G. Mann, J. C. Segovia, Diego Bossini, D. Katz, Nicholas Rowell, P. Ramos, E. Racero, G. Gracia-Abril, R. Santoveña, R. Haigron, N. Unger, Enrique Solano, S. G. Baker, W. J. Cooper, F. Royer, S. Accart, George M. Seabroke, João Alves, Emese Plachy, Thomas Hilger, Pedro García-Lario, Gérard Jasniewicz, Kevin Benson, Christos Siopis, J. Souchay, Agnes Fienga, Giovanni Comoretto, F. Julbe, A. Hutton, Pierre Fernique, Céline Reylé, F. Pailler, Stefan Jordan, J. H. J. de Bruijne, C. A. Stephenson, E. Gerlach, Elisa Distefano, Karri Muinonen, Y. Viala, H. Zhao, L. Siltala, C. P. Murphy, Maria-Rosa L. Cioni, Andrea Chiavassa, D. Molina, J. Fernández-Hernández, G. Jevardat de Fombelle, Federico Marocco, Nicoletta Sanna, Alexey Mints, Juan Zorec, Ángel Gómez, I. Bellas-Velidis, M. G. Lattanzi, C. M. Raiteri, E. Brugaletta, Mikael Granvik, O. L. Creevey, Guy Rixon, Francois Mignard, P. M. Marrese, M. A. Álvarez, Caroline Soubiran, Rene Andrae, C. Ordénovic, A. Delgado, V. Sanchez Gimenez, J. Castañeda, D. Vicente, R. De March, A. Garcia-Gutierrez, M. Weiler, F. Thévenin, Lennart Lindegren, Isabelle Lecoeur-Taïbi, Jon Marchant, Monica Rainer, Alessandro Spagna, Andrej Prsa, M. Sarasso, Nicolas Rambaux, Paul J. McMillan, Ludovic Delchambre, M. Garcia-Reinaldos, M. Haywood, C. Fouron, S. Girona, Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Universidad de Barcelona, Xunta de Galicia, Generalitat de Catalunya, INAF - Osservatorio Astrofisico di Torino (OATo), Istituto Nazionale di Astrofisica (INAF), Univers, Transport, Interfaces, Nanostructures, Atmosphère et environnement, Molécules (UMR 6213) (UTINAM), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Institut de Planétologie et d'Astrophysique de Grenoble (IPAG), Centre National d'Études Spatiales [Toulouse] (CNES)-Observatoire des Sciences de l'Univers de Grenoble (OSUG ), Institut national des sciences de l'Univers (INSU - CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Grenoble Alpes (UGA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Grenoble Alpes (UGA), Galaxies, Etoiles, Physique, Instrumentation (GEPI), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Joseph Louis LAGRANGE (LAGRANGE), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Centre National d'Études Spatiales [Toulouse] (CNES), Laboratoire d'Astrophysique de Bordeaux [Pessac] (LAB), Université de Bordeaux (UB)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Astronomische Rechen-Institut [Heidelberg] (ARI), Zentrum für Astronomie der Universität Heidelberg (ZAH), Universität Heidelberg [Heidelberg]-Universität Heidelberg [Heidelberg], Systèmes de Référence Temps Espace (SYRTE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut de Mécanique Céleste et de Calcul des Ephémérides (IMCCE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Lille-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Observatoire astronomique de Strasbourg (ObAS), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS), Mésocentre de calcul (MESOCENTRE), Université de Franche-Comté (UFC), Centre de Données Astronomiques de Strasbourg, Partenaires INRAE, Géoazur (GEOAZUR 7329), Université Côte d'Azur (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Laboratoire Univers et Particules de Montpellier (LUPM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Montpellier 2 - Sciences et Techniques (UM2), Laboratoire d'études spatiales et d'instrumentation en astrophysique (LESIA (UMR_8109)), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut de Physique de Rennes (IPR), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS), Institut de recherche en astrophysique et planétologie (IRAP), Institut national des sciences de l'Univers (INSU - CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Observatoire Midi-Pyrénées (OMP), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS), THALES, Université de Namur [Namur] (UNamur), Institut d'Astrophysique de Paris (IAP), Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut national des sciences de l'Univers (INSU - CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Grenoble Alpes (UGA)-Météo-France -Institut national des sciences de l'Univers (INSU - CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Grenoble Alpes (UGA)-Météo-France, Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Universität Heidelberg [Heidelberg] = Heidelberg University-Universität Heidelberg [Heidelberg] = Heidelberg University, Université de Strasbourg (UNISTRA)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'études spatiales et d'instrumentation en astrophysique = Laboratory of Space Studies and Instrumentation in Astrophysics (LESIA), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), THALES [France], Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS), Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Université Montpellier 2 - Sciences et Techniques (UM2)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Universidad de Cantabria, Gaia Collaboration, Planetary-system research, Department of Physics, Particle Physics and Astrophysics, Astronomy, and ITA

Subjects
trigonometric parallaxes, Solar neighborhood, Stars: luminosity function, mass function, Astronomy, Astrophysics, 01 natural sciences, luminosity function, mass function [Stars], Astronomi, astrofysik och kosmologi, luminosity: mass function [Stars], Astronomy, Astrophysics and Cosmology, MAIN-SEQUENCE, Hertzsprung-Russell-diagram, 010303 astronomy & astrophysics, Stars:low-mass brown-dwarfs, wide binaries, Physics, education.field_of_study, north galactic pole, Astrophysics::Instrumentation and Methods for Astrophysics, Astrometry, BROWN DWARF, Astrophysics - Solar and Stellar Astrophysics, mass function, NORTH GALACTIC POLE, Physical Sciences, symbols, CIRCULAR-VELOCITY CURVE, Halo, astro-ph.SR, Hertzsprung–Russell diagram, stars: luminosity function, astro-ph.GA, Posterior probability, Population, main-sequence, Luminosity-Function, FOS: Physical sciences, Mass-Function, Astronomy & Astrophysics, Computer Science::Digital Libraries, Photometry (optics), DWARF LUMINOSITY-FUNCTION, dwarf luminosity-function, sky-survey, symbols.namesake, Settore FIS/05 - Astronomia e Astrofisica, luminosity function [stars], low-mass [Stars], 0103 physical sciences, Stars: luminosity: mass function, Stars: low-mass, WHITE-DWARFS, education, Solar and Stellar Astrophysics (astro-ph.SR), brown dwarf, catalogs, astrometry, Hertzsprung-Russell and C-M diagrams, stars: low-mass, solar neighborhood, Astrophysics - Astrophysics of Galaxies, SKY-SURVEY, white-dwarfs, Science & Technology, 010308 nuclear & particles physics, Luminosity function, White dwarf, TRIGONOMETRIC PARALLAXES, Astronomy and Astrophysics, Low-mass, 115 Astronomy, Space science, WIDE BINARIES, Stars, Physics::History of Physics, 13. Climate action, Space and Planetary Science, Astrophysics of Galaxies (astro-ph.GA), solar-neighborhood, Catalogs, circular-velocity curve, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
Abstract

Aims. We produce a clean and well-characterised catalogue of objects within 100 pc of the Sun from the Gaia Early Data Release 3. We characterise the catalogue through comparisons to the full data release, external catalogues, and simulations. We carry out a first analysis of the science that is possible with this sample to demonstrate its potential and best practices for its use., Methods. Theselection of objects within 100 pc from the full catalogue used selected training sets, machine-learning procedures, astrometric quantities, and solution quality indicators to determine a probability that the astrometric solution is reliable. The training set construction exploited the astrometric data, quality flags, and external photometry. For all candidates we calculated distance posterior probability densities using Bayesian procedures and mock catalogues to define priors. Any object with reliable astrometry and a non-zero probability of being within 100 pc is included in the catalogue., Results. We have produced a catalogue of 331 312 objects that we estimate contains at least 92% of stars of stellar type M9 within 100 pc of the Sun. We estimate that 9% of the stars in this catalogue probably lie outside 100 pc, but when the distance probability function is used, a correct treatment of this contamination is possible. We produced luminosity functions with a high signal-to-noise ratio for the main-sequence stars, giants, and white dwarfs. We examined in detail the Hyades cluster, the white dwarf population, and wide-binary systems and produced candidate lists for all three samples. We detected local manifestations of several streams, superclusters, and halo objects, in which we identified 12 members of Gaia Enceladus. We present the first direct parallaxes of five objects in multiple systems within 10 pc of the Sun., Conclusions. We provide the community with a large, well-characterised catalogue of objects in the solar neighbourhood. This is a primary benchmark for measuring and understanding fundamental parameters and descriptive functions in astronomy.

Published
2021

22. Robustness evaluation of production plans using Monte Carlo simulation

Author

Felix Franke, Ralph Riedel, and Susanne Franke

Subjects
Production planning, Operations research, Artificial Intelligence, Order (exchange), Computer science, Process (engineering), Monte Carlo method, Production (economics), Plan (drawing), Robustness (economics), Productivity, Industrial and Manufacturing Engineering
Abstract

In order to meet the challenges on the global market and to maximize productivity, production companies need to develop an effective production planning strategy. Production planning is a complex process that underlies a dynamic, fast-paced behavior: influences like machine failure, change of order or absence of employees regularly require an adaptation of the existing production plan. In this paper, we present a methodology that models phenomena influencing the production plan and evaluates their effects on the completion times via a Monte Carlo simulation. Focusing on short-notice incoming orders, the methodology provides statements on the robustness of the production plan by estimating the anticipated change in the completion times under the occurrence of uncertain events.

Published
2021

24. Perceptual saccadic suppression starts in the retina

Author

Thomas Münch, Saad Idrees, Felix Franke, Ziad M. Hafed, and Matthias Baumann

Subjects
Male, Visual perception, genetic structures, Photic Stimulation, Swine, Computer science, General Physics and Astronomy, Visual processing, Mice, chemistry.chemical_compound, 0302 clinical medicine, lcsh:Science, media_common, Neurons, 0303 health sciences, Multidisciplinary, Visual sensitivity, medicine.anatomical_structure, Visual Perception, Female, Adult, media_common.quotation_subject, Science, Image processing, Fixation, Ocular, General Biochemistry, Genetics and Molecular Biology, Article, Retina, Young Adult, 03 medical and health sciences, Perception, Reaction Time, Saccades, medicine, Animals, Humans, Vision, Ocular, 030304 developmental biology, Eye movement, Retinal, General Chemistry, Saccadic masking, eye diseases, Mice, Inbred C57BL, chemistry, Fixation (visual), lcsh:Q, sense organs, Visual Fields, Neuroscience, 030217 neurology & neurosurgery
Abstract

Visual sensitivity, probed through perceptual detectability of very brief visual stimuli, is strongly impaired around the time of rapid eye movements. This robust perceptual phenomenon, called saccadic suppression, is frequently attributed to active suppressive signals that are directly derived from eye movement commands. Here we show instead that visual-only mechanisms, activated by saccade-induced image shifts, can account for all perceptual properties of saccadic suppression that we have investigated. Such mechanisms start at, but are not necessarily exclusive to, the very first stage of visual processing in the brain, the retina. Critically, neural suppression originating in the retina outlasts perceptual suppression around the time of saccades, suggesting that extra-retinal movement-related signals, rather than causing suppression, may instead act to shorten it. Our results demonstrate a far-reaching contribution of visual processing mechanisms to perceptual saccadic suppression, starting in the retina, without the need to invoke explicit motor-based suppression commands., Nature Communications, 11 (1), ISSN:2041-1723

Published
2020

25. Suppression without inhibition: how retinal computation contributes to saccadic suppression

Author

Ziad M. Hafed, Katrin Franke, Felix Franke, Timm Schubert, Saad Idrees, Alexandra Kling, Matthias-Philipp Baumann, Thomas Münch, and Maria M. Korympidou

Subjects
Retina, Visual perception, genetic structures, Swine, Retinal, Biology, Saccadic masking, Mice, Electrophysiology, chemistry.chemical_compound, Calcium imaging, medicine.anatomical_structure, chemistry, Receptive field, Saccades, Visual Perception, Psychophysics, medicine, Animals, Humans, sense organs, Neuroscience, Photic Stimulation, Vision, Ocular
Abstract

Visual perception remains stable across saccadic eye movements, despite the concurrent strongly disruptive visual flow. This stability is partially associated with a reduction in visual sensitivity, known as saccadic suppression, which already starts in the retina with reduced ganglion cell sensitivity. However, the retinal circuit mechanisms giving rise to such suppression remain unknown. Here, we describe these mechanisms using electrophysiology in mouse, pig, and macaque retina, 2-photon calcium imaging, computational modeling, and human psychophysics. We find that sequential stimuli, like those that naturally occur during saccades, trigger three independent suppressive mechanisms in the retina. The main mechanism is triggered by contrast-reversing sequential stimuli and originates within the receptive field center of ganglion cells. It does not involve inhibition or other known suppressive mechanisms like saturation or adaptation. Instead, it relies on temporal filtering of the inherently slow response of cone photoreceptors coupled with downstream nonlinearities. Two further mechanisms of suppression are present predominantly in ON ganglion cells and originate in the receptive field surround, highlighting another disparity between ON and OFF ganglion cells. The mechanisms uncovered here likely play a role in shaping the retinal output following eye movements and other natural viewing conditions where sequential stimulation is ubiquitous., Communications Biology, 5, ISSN:2399-3642

Published
2022
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27. Assessing the Ion Transport Properties of Highly Concentrated Non‐Flammable Electrolytes in a Commercial Li‐Ion Battery Cell

Author

Fabian Sälzer, Felix Franke, Lars Pateras Pescara, Jacqueline Winkler, Michael Schwalm, Clemens Müller, and Bernhard Roling

Subjects
Flammable liquid, Materials science, Battery cell, Energy Engineering and Power Technology, Electrolyte, Ion, Dielectric spectroscopy, chemistry.chemical_compound, chemistry, Chemical engineering, Ionic liquid, Electrochemistry, Electrical and Electronic Engineering, Ion transporter
Published
2019

28. The Galactic Anticentre

Author

Vincenzo Ripepi, A. de Torres, Annie C. Robin, Mariateresa Crosta, C. Diener, L. Noval, Daniel Michalik, P. J. Richards, L. Karbevska, K. Kruszyńska, E. Fraile, André Moitinho, Michał Pawlak, P. Panuzzo, M. Riello, Benoit Carry, A. Yoldas, Harry Enke, N. Tonello, P. Gavras, M. Vaillant, Rosanna Sordo, E. del Pozo, Lorenzo Rimoldini, M. Bernet, G. Orrù, W. van Reeven, J. M. Martín-Fleitas, S. Diakite, P. Burgess, P. Osborne, Derek W. Morris, M. I. Carnerero, Amina Helmi, Mike Smith, Iain A. Steele, Alessandro Sozzetti, M. Kontizas, A. Sagristà Sellés, Roberto Molinaro, B. Holl, D. Baines, D. Molina, J. Fernández-Hernández, S. Marinoni, Michele Bellazzini, Maria Süveges, Teresa Antoja, D. Barbato, Uwe Lammers, Isabella Pagano, Davide Massari, G. Plum, P. Ramos, G. Jevardat de Fombelle, M. Biermann, C. Crowley, Mathias Schultheis, D. W. Evans, P. A. Palicio, Paolo Montegriffo, Ramachrisna Teixeira, R. Blomme, Elmé Breedt, T. A. Lister, F. A. Jansen, Ruth Carballo, Marcella Marconi, A. Abreu Aramburu, J. M. Carrasco, F. Royer, S. Accart, A. Burlacu, S. Regibo, Andrej Prsa, M. Sarasso, Nicolas Rambaux, A. F. Mulone, Ana Ulla, Eric Gosset, Alessandra Mastrobuono-Battisti, George M. Seabroke, H. E. Delgado, Federico Marocco, C. Nicolas, T. Lebzelter, Nami Mowlavi, C. Barache, Nicoletta Sanna, G. Gracia-Abril, R. Santoveña, R. Haigron, N. Unger, Silvio Leccia, A. Jean-Antoine Piccolo, A. F. Lanza, Alberto Vecchiato, Thomas Wevers, F. Figueras, G. Busso, C. Fabre, P. Di Matteo, F. Riclet, F. Solitro, Eric Slezak, N. Samaras, João Alves, Emese Plachy, Timo Prusti, F. van Leeuwen, J. Osinde, O. Marchal, M. Ajaj, C. Ducourant, Tatiana Muraveva, Shay Zucker, H. Steidelmüller, Alberto Riva, D. Semeux, N. Cheek, Laurent Galluccio, Martin A. Barstow, Alex Bombrun, S. Liao, M. van Leeuwen, R. E. de Souza, P. de Laverny, T. Roegiers, Paul J. McMillan, G. Holland, Alexey Mints, G. Giuffrida, L. M. Sarro, Juan Zorec, G. Sadowski, P. Yvard, Carme Jordi, J. L. Halbwachs, Laurent Chemin, Ludovic Delchambre, M. Garcia-Reinaldos, Ugo Becciani, Diego Bossini, Ángel Gómez, Sergi Blanco-Cuaresma, Rossella Cancelliere, C. Fabricius, J. De Ridder, L. Eyer, L. Pulone, Simon Hodgkin, Ennio Poretti, F. De Angeli, M. Haywood, E. Anglada Varela, Antonella Vallenari, F. X. Pineau, D. Garabato, A. Guerrier, H. E. P. Lindstrøm, Thomas Hilger, I. Bellas-Velidis, Frédéric Arenou, Paolo Giacobbe, Ilaria Musella, Tristan Cantat-Gaudin, L. Palaversa, Pedro García-Lario, David Hobbs, C. Turon, E. Balbinot, P. de Teodoro, Sébastien Lambert, D. Katz, Angela Bragaglia, Anthony G. A. Brown, Paolo Tanga, P. Castro Sampol, J. C. Segovia, Alejandra Recio-Blanco, Yves Fremat, Jon Marchant, Jose M Hernandez, S. Ragaini, Sofia Randich, P. Re Fiorentin, J. F. Le Campion, Gisella Clementini, M. Segol, P. David, R. Drimmel, F. Crifo, J. Guiraud, M. David, R. L. Smart, M. Fabrizio, I. Gonzalez-Santamaria, D. Eappachen, M. G. Lattanzi, Miguel García-Torres, Andreas Korn, S. Voutsinas, László Molnár, Simchon Faigler, A. Mora, Nicholas Rowell, Antti Penttilä, R. Geyer, Sanjeev Khanna, Aldo Dell'Oro, H. E. Huckle, C. Dolding, N. Leclerc, Monica Rainer, R. Mor, J. Bakker, Maroussia Roelens, Douglas J. Marshall, A. G. Butkevich, Nigel Hambly, A. Masip, Laia Casamiquela, R. Messineo, Martin Altmann, A. M. Piersimoni, Alessandro Spagna, Gerry Gilmore, Stefano Bertone, Patrick Charlot, O. Vanel, Daniel Hestroffer, Marco Castellani, Sebastian L. Hidalgo, W. Roux, Łukasz Wyrzykowski, Krzysztof A. Rybicki, M. M. S. Marcos Santos, Raphael Guerra, Alberto Cellino, E. Poggio, Gérard Jasniewicz, J. J. González-Vidal, S. Cowell, Peter G. Jonker, C. M. Raiteri, S. Bartolomé, J. Álvarez Cid-Fuentes, Elisabetta Caffau, J. J. Aguado, N. R. Millar, Ulrike Heiter, Federica Spoto, Felix Franke, A. Baudesson-Stella, M. Barros, Tsevi Mazeh, A. Panahi, E. Brugaletta, R. Buzzi, Elena Pancino, G. Altavilla, E. Racero, Enrique Solano, Mikael Granvik, Minia Manteiga, C. Robin, Tomaz Zwitter, Deborah Busonero, Alberto Krone-Martins, Marc Audard, Kevin Benson, Christos Siopis, L. Balaguer-Núñez, C. A. L. Bailer-Jones, E. Poujoulet, O. L. Creevey, E. Szegedi-Elek, C. Fouron, Michael Davidson, E. Licata, Despina Hatzidimitriou, Mark Cropper, Z. Kostrzewa-Rutkowska, S. Managau, A. Dapergolas, Sergio Messina, Laszlo Szabados, H. I. Siddiqui, W. Löffler, Mario Gai, J.-B. Delisle, Leanne P. Guy, S. G. Baker, W. J. Cooper, Alfred Castro-Ginard, Conny Aerts, A. Lorca, Xavier Luri, Damien Ségransan, Grigori Fedorets, A. Garofalo, J. Juaristi Campillo, F. De Luise, F. Pailler, F. Taris, L. Bramante, Thierry Morel, T. Cornez, L. Martin Polo, M. Ramos-Lerate, Jordi Portell, E. Salguero, Sergei A. Klioner, K. Janßen, Ulrich Bastian, Stefan Jordan, P. Esquej, A. C. Lanzafame, Beatrice Bucciarelli, C. Panem, Y. Lebreton, Carlos Dafonte, S. Girona, D. Munoz, Dimitri Pourbaix, William Thuillot, J. H. J. de Bruijne, N. Brouillet, L. Chaoul, F. Torra, Alex Lobel, J.-L. Bassilana, Francesca Fragkoudi, M. Romero-Gómez, C. A. Stephenson, T. Pauwels, Eva Sciacca, Alessandro Bressan, Morgan Fouesneau, E. Livanou, E. Gerlach, X. Peñalosa Esteller, Roberto Morbidelli, L. Rohrbasser, Johannes Sahlmann, Elisa Distefano, P. Sartoretti, Karri Muinonen, Zoltan Balog, Y. Viala, J. Torra, H. Zhao, L. Siltala, G. Tauran, D. Souami, P. Madrero Pardo, David Teyssier, Jesus Salgado, J. Souchay, C. P. Murphy, Maria-Rosa L. Cioni, N. A. Walton, S. Bouquillon, Andrea Chiavassa, Agnes Fienga, Giovanni Comoretto, F. Julbe, A. Hutton, Yassine Damerdji, Richard I. Anderson, Pierre Fernique, Céline Reylé, M. Hauser, E. Utrilla, Pierre Kervella, C. Zurbach, Robert G. Mann, Ummi Abbas, Hector Canovas, D. L. Harrison, Y. Lasne, Mark Taylor, Y. Le Fustec, E. F. del Peloso, N. Bauchet, E. van Dillen, Jan Rybizki, N. Hładczuk, T. Boch, J. González-Núñez, Carine Babusiaux, C. Pagani, Krzysztof Nienartowicz, Eduard Masana, G. Kordopatis, N. Robichon, Luciana Bianchi, R. Gutiérrez-Sánchez, Arnaud Siebert, A. Kochoska, T. Carlucci, Jérôme Berthier, J. Castañeda, D. Vicente, R. De March, A. Garcia-Gutierrez, M. Weiler, F. Thévenin, Lennart Lindegren, Isabelle Lecoeur-Taïbi, Guy Rixon, Francois Mignard, P. M. Marrese, M. A. Álvarez, Caroline Soubiran, Rene Andrae, C. Ordénovic, A. Delgado, V. Sanchez Gimenez, Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Universidad de Barcelona, Xunta de Galicia, European Commission, Centros de Excelencia Severo Ochoa, BARCELONA SUPERCOMPUTING CENTER (BSC), SEV2015-0493, Krone Martins, A. [0000-0002-2308-6623], McMillan, P. [0000-0002-8861-2620], Carrasco Martínez, J. P. [0000-0002-3029-5853], Sozzetti, A. [0000-0002-7504-365X], Unidad de Excelencia Científica María de Maeztu Centro de Astrobiología del Instituto Nacional de Técnica Aeroespacial y CSIC, MINECO/ICTI2013-2016/MDM-2014-0369, Centrode Excelencia Científica Instituto de Ciencias del Cosmos Universidad de Barcelona, MINECO/ICTI2013-2016/SEV2015-0493, Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), National Natural Science Foundation of China (NSFC), Estonian Ministry of Education and Research, Centre National D'Etudes Spatiales (CNES), Agence Nationale de la Recherche (ANR), Centre National de la Recherche Scientifique (CNRS), European Commission (EC), European Research Council (ERC), Institut des Sciences de l'Univers (INSU), Institut National Polytechnique (INP), Institut National de Physique nucleaire et de Physique des Particules (IN2P3), Deutsches Zentrum für Luft- und Raumfahrt (DLR), Hungarian Academy of Sciences, Hungarian National Research, Development, and Innovation Office (NKFIH), Science Foundation Ireland (SFI), Israel Science Foundation (ISF), Agenzia Spaziale Italiana (ASI), Italian Istituto Nazionale di Astrofisica (INAF), Netherlands Organisation for Scientific Research (NWO), Polish National Science Centre, Ministry of Science and Higher Education (MNiSW), Fundacao para a Ciencia e a Tecnologia (FCT), Slovenian Research Agency, Agencia Estatal de Investigación (AEI), Generalitat de Catalunya, United Kingdom Science and Technology Facilities Council (STFC), United Kingdom Space Agency (UKSA), Gaia Collaboration, Universidad de Cantabria, Astronomy, Kapteyn Astronomical Institute, Institut de Ciencies del Cosmos (ICCUB), Universitat de Barcelona (UB), Joseph Louis LAGRANGE (LAGRANGE), Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Kapteyn Astronomical Institute [Groningen], University of Groningen [Groningen], INAF - Osservatorio Astronomico di Padova (OAPD), Istituto Nazionale di Astrofisica (INAF), Institut de recherches sur la catalyse et l'environnement de Lyon (IRCELYON), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), M2A 2021, Laboratoire d'Astrophysique de Bordeaux [Pessac] (LAB), Université de Bordeaux (UB)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Bordeaux (UB)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'études spatiales et d'instrumentation en astrophysique (LESIA (UMR_8109)), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut de Physique de Rennes (IPR), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS), Planetary-system research, Department of Physics, Particle Physics and Astrophysics, Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'études spatiales et d'instrumentation en astrophysique = Laboratory of Space Studies and Instrumentation in Astrophysics (LESIA), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS), Université Nice Sophia Antipolis (... - 2019) (UNS), and Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)

Subjects
trigonometric parallaxes, SOLAR NEIGHBORHOOD, Astronomy, SAGITTARIUS DWARF GALAXY, Astrophysics, 01 natural sciences, sagittarius dwarf galaxy, 010303 astronomy & astrophysics, Physics, [SDU.ASTR]Sciences of the Universe [physics]/Astrophysics [astro-ph], solar neighborhood, Astrophysics::Instrumentation and Methods for Astrophysics, Astrometry, Gelexy: kinematics and dynamics, Kinematics and Dynamics, Open clusters and asssociations: individual: Berkeley 29, sky survey, Disk, Physical Sciences, kinematics and dynamics [Gelexy], old open clusters, MILKY-WAY, Astrophysics::Earth and Planetary Astrophysics, open clusters and associations: individual: Berkeley 29, Galaxy: kinematics and dynamics, disk [Galaxy], individual: Berkeley 29 [open clusters and associations], Astrometria, Berkeley 29, EXPLORING HALO SUBSTRUCTURE, LOCAL KINEMATICS, Milky Way, FOS: Physical sciences, Open Clusters and Associations, Individual, exploring halo substructure, Astrophysics::Cosmology and Extragalactic Astrophysics, Astronomy & Astrophysics, Computer Science::Digital Libraries, stellar structure, Galaxy: disk, Open clusters and associations: individual: Saurer 1, Galactic halo, Halo, Settore FIS/05 - Astronomia e Astrofisica, individual: Berkeley 29 [Open clusters and asssociations], 0103 physical sciences, distances [stars], halo [Galaxy], Disc, Stars: distances, milky-way, Saurer 1, Astrophysics::Galaxy Astrophysics, canis-major, Science & Technology, 010308 nuclear & particles physics, TRIGONOMETRIC PARALLAXES, Galaxy: halo, stars: distances, open clusters and associations: individual: Saurer 1, Astrophysics - Astrophysics of Galaxies, Astronomy and Astrophysics, Galactic plane, kinematics and dynamics [Galaxy], 115 Astronomy, Space science, CANIS-MAJOR, Stars, Galaxy, Physics::History of Physics, Estels, individual: Saurer 1 [open clusters and associations], Distances, local kinematics, OLD OPEN CLUSTERS, Space and Planetary Science, Astrophysics of Galaxies (astro-ph.GA), SKY SURVEY, Open cluster, STELLAR STRUCTURE
Abstract

Aims. We aim to demonstrate the scientific potential of the Gaia Early Data Release 3 (EDR3) for the study of different aspects of the Milky Way structure and evolution and we provide, at the same time, a description of several practical aspects of the data and examples of their usage., Methods. We used astrometric positions, proper motions, parallaxes, and photometry from EDR3 to select different populations and components and to calculate the distances and velocities in the direction of the anticentre. In this direction, the Gaia astrometric data alone enable the calculation of the vertical and azimuthal velocities; also, the extinction is relatively low compared to other directions in the Galactic plane. We then explore the disturbances of the current disc, the spatial and kinematical distributions of early accreted versus in situ stars, the structures in the outer parts of the disc, and the orbits of open clusters Berkeley 29 and Saurer 1., Results. With the improved astrometry and photometry of EDR3, we find that: (i) the dynamics of the Galactic disc are very complex with oscillations in the median rotation and vertical velocities as a function of radius, vertical asymmetries, and new correlations, including a bimodality with disc stars with large angular momentum moving vertically upwards from below the plane, and disc stars with slightly lower angular momentum moving preferentially downwards; (ii) we resolve the kinematic substructure (diagonal ridges) in the outer parts of the disc for the first time; (iii) the red sequence that has been associated with the proto-Galactic disc that was present at the time of the merger with Gaia-Enceladus-Sausage is currently radially concentrated up to around 14 kpc, while the blue sequence that has been associated with debris of the satellite extends beyond that; (iv) there are density structures in the outer disc, both above and below the plane, most probably related to Monoceros, the Anticentre Stream, and TriAnd, for which the Gaia data allow an exhaustive selection of candidate member stars and dynamical study; and (v) the open clusters Berkeley 29 and Saurer 1, despite being located at large distances from the Galactic centre, are on nearly circular disc-like orbits., Conclusions. Even with our simple preliminary exploration of the Gaia EDR3, we demonstrate how, once again, these data from the European Space Agency are crucial for our understanding of the different pieces of our Galaxy and their connection to its global structure and history.

Published
2021
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29. Gaia early data release 3: summary of the contents and survey properties (Corrigendum)

Author

Mathias Schultheis, Marcella Marconi, N. Robichon, Luciana Bianchi, F. Crifo, J. Guiraud, D. Eappachen, R. Gutiérrez-Sánchez, Sanjeev Khanna, A. M. Piersimoni, Raphael Guerra, J. J. González-Vidal, J. J. Aguado, N. R. Millar, A. Baudesson-Stella, Tristan Cantat-Gaudin, Alejandra Recio-Blanco, Ummi Abbas, Francesca Figueras, R. Blomme, Elmé Breedt, G. Busso, A. Jean-Antoine Piccolo, Gerry Gilmore, A. Panahi, S. Messina, C. Babusiaux, Łukasz Wyrzykowski, Mark Taylor, Alex Bombrun, M. Barros, M. Riello, M. Ajaj, C. Ducourant, Tatiana Muraveva, Alberto Cellino, E. Poggio, Y. Le Fustec, C. P. Murphy, Maria-Rosa L. Cioni, Hector Canovas, D. L. Harrison, Y. Lasne, Elena Pancino, N. Bauchet, G. Orrù, Sergi Blanco-Cuaresma, Simon Hodgkin, Ennio Poretti, A. F. Lanza, Alberto Vecchiato, Thomas Wevers, Andrea Chiavassa, E. Szegedi-Elek, A. G. A. Brown, Laszlo Szabados, A. Masip, Laia Casamiquela, R. Messineo, C. Crowley, Alessandra Mastrobuono-Battisti, E. Poujoulet, Zoltan Balog, L. Eyer, A. Guerrier, H. E. P. Lindstrøm, Ilaria Musella, Laurent Galluccio, Martin A. Barstow, Aldo Dell'Oro, Mark Cropper, Z. Kostrzewa-Rutkowska, Angela Bragaglia, Arnaud Siebert, Damien Ségransan, A. Kochoska, J. L. Halbwachs, E. F. del Peloso, N. Hładczuk, F. Pailler, Stefan Jordan, Stefano Bertone, L. Pulone, Frédéric Arenou, Patrick Charlot, David Hobbs, P. Castro Sampol, Yves Fremat, Sofia Randich, Marc Audard, Despina Hatzidimitriou, A. Dapergolas, L. Palaversa, W. van Reeven, M. Hauser, E. Utrilla, Georges Kordopatis, Sergei A. Klioner, Alex Lobel, J.-L. Bassilana, G. Tauran, T. Prusti, H. Steidelmüller, Alberto Riva, Diego Bossini, Maria Süveges, Isabella Pagano, J. H. J. de Bruijne, Elisabetta Caffau, Federica Spoto, Felix Franke, T. Boch, M. I. Carnerero, T. Carlucci, Grigori Fedorets, J. Castañeda, W. Löffler, Enrique Solano, Paolo Montegriffo, A. Abreu Aramburu, T. Lebzelter, Nami Mowlavi, C. Barache, C. A. Stephenson, A. Lorca, L. Bramante, Amina Helmi, J.-B. Delisle, B. Holl, D. Molina, J. Fernández-Hernández, G. Jevardat de Fombelle, F. van Leeuwen, C. Robin, D. Katz, E. Gerlach, Elisa Distefano, Michele Bellazzini, P. de Laverny, G. Sadowski, Tomaz Zwitter, A. Burlacu, Teresa Antoja, Rossella Cancelliere, F. Torra, C. Pagani, Annie C. Robin, Johannes Sahlmann, Karri Muinonen, Eva Sciacca, D. Vicente, Krzysztof Nienartowicz, A. F. Mulone, Shay Zucker, Nicholas Rowell, H. E. Delgado, Dimitri Pourbaix, G. Giuffrida, H. E. Huckle, Federico Marocco, L. Noval, Daniel Michalik, P. J. Richards, Y. Viala, E. van Dillen, L. Karbevska, H. Zhao, L. Siltala, Nicoletta Sanna, K. Kruszyńska, E. Fraile, R. De March, Y. Lebreton, C. M. Raiteri, D. W. Evans, Ana Ulla, Francesca Fragkoudi, Jan Rybizki, E. Brugaletta, L. Rohrbasser, Andreas Korn, S. G. Baker, A. Garcia-Gutierrez, L. M. Sarro, R. Buzzi, T. Pauwels, Jérôme Berthier, L. Chaoul, W. J. Cooper, Eduard Masana, M. van Leeuwen, D. Garabato, P. Panuzzo, Maroussia Roelens, Benoit Carry, Deborah Busonero, Michael Davidson, J. González-Núñez, Thomas Hilger, E. Licata, M. Weiler, Mikael Granvik, Alessandro Bressan, Morgan Fouesneau, Miguel García-Torres, W. Roux, Pedro García-Lario, Iain A. Steele, P. Ramos, Alessandro Sozzetti, Roberto Molinaro, O. L. Creevey, D. Barbato, Lorenzo Rimoldini, Uwe Lammers, Alexey Mints, P. Sartoretti, E. Livanou, D. Souami, P. Madrero Pardo, David Teyssier, M. Bernet, Yassine Damerdji, X. Peñalosa Esteller, C. Fabre, F. Thévenin, Gérard Jasniewicz, Roberto Morbidelli, Jesus Salgado, Juan Zorec, Ángel Gómez, Douglas J. Marshall, A. G. Butkevich, M. Biermann, E. Racero, J. Torra, R. Gomel, O. Vanel, Daniel Hestroffer, Sebastian L. Hidalgo, P. A. Palicio, F. De Angeli, Richard L. Smart, J. M. Martín-Fleitas, Derek W. Morris, F. Royer, S. Diakite, S. Accart, C. Dolding, P. Burgess, Richard I. Anderson, A. Garofalo, I. Bellas-Velidis, George M. Seabroke, P. Osborne, Claus Fabricius, Jon Marchant, Ramachrisna Teixeira, João Alves, G. Gracia-Abril, R. Santoveña, R. Haigron, N. Unger, Lennart Lindegren, Isabelle Lecoeur-Taïbi, Paolo Giacobbe, Emese Plachy, M. Fabrizio, I. Gonzalez-Santamaria, F. Taris, Kevin Benson, Christos Siopis, M. M. S. Marcos Santos, S. Cowell, Jose M Hernandez, S. Ragaini, Jordi Portell, Linda K. Molnar, R. Drimmel, Pierre Kervella, C. Zurbach, S. Bartolomé, J. Álvarez Cid-Fuentes, E. Salguero, Ulrich Bastian, Robert G. Mann, Marco Castellani, J. Osinde, E. Balbinot, Caroline Soubiran, Rene Andrae, J. Souchay, M. G. Lattanzi, S. Voutsinas, Agnes Fienga, Giovanni Comoretto, P. Esquej, A. C. Lanzafame, Beatrice Bucciarelli, C. Panem, Carlos Dafonte, Alfred Castro-Ginard, J. C. Segovia, Monica Rainer, F. Julbe, A. Hutton, Peter G. Jonker, William Thuillot, A. de Torres, F. De Luise, Pierre Fernique, Céline Reylé, M. Kontizas, G. Plum, Martin Altmann, L. Martin Polo, M. Ramos-Lerate, P. de Teodoro, Sébastien Lambert, G. Altavilla, André Moitinho, D. Munoz, N. Brouillet, Alessandro Spagna, C. Ordénovic, Gisella Clementini, C. Nicolas, Michał Pawlak, Silvio Leccia, A. Delgado, M. Romero-Gómez, N. Cheek, A. Yoldas, Harry Enke, Rosanna Sordo, V. Sanchez Gimenez, Mike Smith, P. David, D. Baines, Paolo Tanga, Guy Rixon, Alberto Krone-Martins, S. Managau, N. A. Walton, S. Bouquillon, C. Fouron, Francois Mignard, Xavier Luri, J. Juaristi Campillo, S. Girona, Thierry Morel, T. Cornez, P. M. Marrese, M. A. Álvarez, S. Liao, Andrej Prsa, M. Sarasso, Nicolas Rambaux, Paul J. McMillan, Ludovic Delchambre, M. Garcia-Reinaldos, M. Haywood, E. Anglada Varela, Antonella Vallenari, S. Regibo, R. E. de Souza, Sahar Shahaf, J. De Ridder, M. Segol, Simchon Faigler, A. Mora, Ulrike Heiter, Carla Cacciari, Minia Manteiga, H. I. Siddiqui, Mario Gai, Leanne P. Guy, N. Leclerc, T. A. Lister, F. A. Jansen, Ruth Carballo, J. M. Carrasco, Bengt Edvardsson, P. Di Matteo, K. Janßen, F. Riclet, F. Solitro, O. Marchal, G. Holland, F. X. Pineau, C. Turon, P. Re Fiorentin, Tsevi Mazeh, Mariateresa Crosta, C. Diener, J. F. Le Campion, Vincenzo Ripepi, M. David, R. Mor, N. Tonello, E. del Pozo, J. Bakker, Davide Massari, A. Sagristà Sellés, Marco Delbo, Eric Slezak, P. Gavras, N. Samaras, S. Marinoni, M. Vaillant, J. M. Petit, P. Yvard, Carme Jordi, Ugo Becciani, Antti Penttilä, R. Geyer, Nigel Hambly, Krzysztof A. Rybicki, L. Balaguer-Núñez, C. A. L. Bailer-Jones, Conny Aerts, Eric Gosset, D. Semeux, T. Roegiers, and Laurent Chemin

Subjects
Physics, Addenda, 010504 meteorology & atmospheric sciences, Errata, Parallaxes, Astronomy, Astronomy and Astrophysics, Astrophysics, Astrometry, Photometric, 01 natural sciences, Techniques, catalogs, astrometry, parallaxes, proper motions, techniques: photometric, errata, addenda, Settore FIS/05 - Astronomia e Astrofisica, Space and Planetary Science, 0103 physical sciences, Proper motions, Catalogs, 010303 astronomy & astrophysics, Data release, 0105 earth and related environmental sciences
Abstract

We present the early installment of the third Gaia data release, Gaia EDR3, consisting of astrometry and photometry for 1.8 billion sources brighter than magnitude 21, complemented with the list of radial velocities from Gaia DR2. Gaia EDR3 contains celestial positions and the apparent brightness in G for approximately 1.8 billion sources. For 1.5 billion of those sources, parallaxes, proper motions, and the (G_BP-G_RP) colour are also available. The passbands for G, G_BP, and G_RP are provided as part of the release. For ease of use, the 7 million radial velocities from Gaia DR2 are included in this release, after the removal of a small number of spurious values. New radial velocities will appear as part of Gaia DR3. Finally, Gaia EDR3 represents an updated materialisation of the celestial reference frame (CRF) in the optical, the Gaia-CRF3, which is based solely on extragalactic sources. The creation of the source list for Gaia EDR3 includes enhancements that make it more robust with respect to high proper motion stars, and the disturbing effects of spurious and partially resolved sources. The source list is largely the same as that for Gaia DR2, but it does feature new sources and there are some notable changes. The source list will not change for Gaia DR3. Gaia EDR3 represents a significant advance over Gaia DR2, with parallax precisions increased by 30 percent, proper motion precisions increased by a factor of 2, and the systematic errors in the astrometry suppressed by 30--40 percent for the parallaxes and by a factor ~2.5 for the proper motions. The photometry also features increased precision, but above all much better homogeneity across colour, magnitude, and celestial position. A single passband for G, G_BP, and G_RP is valid over the entire magnitude and colour range, with no systematics above the 1 percent level.

Published
2021

30. Gaia Early Data Release 3: Acceleration of the solar system from Gaia astrometry

Author

Vincenzo Ripepi, P. Gavras, M. Vaillant, Mathias Schultheis, László Molnár, E. Poujoulet, Mark Cropper, C. Babusiaux, D. Molina, J. Fernández-Hernández, G. Jevardat de Fombelle, A. de Torres, Aldo Dell'Oro, J. Castañeda, Z. Kostrzewa-Rutkowska, A. Bombrun, André Moitinho, Marcella Marconi, Rossella Cancelliere, M. Hauser, M. Ajaj, C. M. Raiteri, L. Eyer, Michał Pawlak, H. I. Siddiqui, C. Ducourant, Tatiana Muraveva, Tsevi Mazeh, A. Panahi, Federico Marocco, Stefano Bertone, D. Vicente, Patrick Charlot, A. Guerrier, R. De March, Mario Gai, J. Souchay, H. E. P. Lindstrøm, Nicoletta Sanna, Agnes Fienga, Giovanni Comoretto, Jon Marchant, A. Lorca, E. Utrilla, A. Garcia-Gutierrez, Ilaria Musella, L. Balaguer-Núñez, Leanne P. Guy, N. Leclerc, E. Brugaletta, A. Yoldas, Harry Enke, Rosanna Sordo, Zoltan Balog, H. E. Huckle, L. Palaversa, Monica Rainer, T. A. Lister, F. A. Jansen, Ruth Carballo, Alessandro Spagna, J. M. Carrasco, Mikael Granvik, Derek W. Morris, F. Julbe, A. Hutton, J. Osinde, D. W. Evans, M. van Leeuwen, M. Weiler, F. Thévenin, F. Torra, Iain A. Steele, Lorenzo Rimoldini, Alessandro Sozzetti, Francesca Fragkoudi, K. Janßen, O. L. Creevey, J. González-Núñez, T. Pauwels, R. Buzzi, Miguel García-Torres, S. Liao, G. Tauran, Lennart Lindegren, C. Fouron, Pierre Fernique, Céline Reylé, P. Di Matteo, E. Szegedi-Elek, F. Pailler, Stefan Jordan, Roberto Molinaro, Elisabetta Caffau, Federica Spoto, Felix Franke, D. Barbato, Isabelle Lecoeur-Taïbi, Tristan Cantat-Gaudin, Alejandra Recio-Blanco, E. Livanou, W. Roux, X. Peñalosa Esteller, P. A. Palicio, J. H. J. de Bruijne, Sergi Blanco-Cuaresma, Deborah Busonero, F. Riclet, Conny Aerts, Georges Kordopatis, Guy Rixon, F. Solitro, Davide Massari, Mike Smith, D. Baines, Roberto Morbidelli, Gerry Gilmore, G. Plum, Alexey Mints, O. Marchal, Juan Zorec, Ángel Gómez, C. A. Stephenson, Michael Davidson, C. Fabricius, E. Licata, Sergio Messina, Laszlo Szabados, M. Biermann, A. Garofalo, G. Holland, F. De Angeli, Andreas Korn, E. Anglada Varela, Grigori Fedorets, S. Girona, E. Gerlach, Antonella Vallenari, M. Riello, Łukasz Wyrzykowski, Damien Ségransan, F. Taris, L. Bramante, Alberto Cellino, S. Regibo, Andrej Prsa, M. Sarasso, E. Poggio, W. Löffler, Paolo Giacobbe, Jordi Portell, Elisa Distefano, Eric Slezak, I. Bellas-Velidis, Nicolas Rambaux, E. Balbinot, J.-B. Delisle, Maroussia Roelens, E. Salguero, P. de Teodoro, E. van Dillen, Y. Lebreton, Francois Mignard, Sergei A. Klioner, Ulrich Bastian, N. Samaras, G. Orrù, R. E. de Souza, P. Esquej, Paul J. McMillan, A. C. Lanzafame, Sébastien Lambert, Beatrice Bucciarelli, Jose M Hernandez, M. Bernet, S. Ragaini, Gisella Clementini, A. F. Mulone, Ludovic Delchambre, C. Panem, Eric Gosset, P. David, M. Garcia-Reinaldos, Ana Ulla, F. Crifo, J. Guiraud, Mariateresa Crosta, L. Chaoul, C. Diener, Carlos Dafonte, Karri Muinonen, Alex Lobel, J.-L. Bassilana, Maria Süveges, Isabella Pagano, Dimitri Pourbaix, D. Eappachen, M. Haywood, R. Drimmel, Y. Viala, S. Voutsinas, D. Semeux, William Thuillot, N. A. Walton, Paolo Montegriffo, A. Abreu Aramburu, C. Fabre, H. Zhao, Alessandro Bressan, S. Bouquillon, Sanjeev Khanna, T. Lebzelter, N. Tonello, L. Siltala, M. G. Lattanzi, C. Crowley, P. Yvard, Carme Jordi, Elena Pancino, E. del Pozo, Jan Rybizki, Nami Mowlavi, C. Barache, Morgan Fouesneau, J. De Ridder, Ugo Becciani, Martin Altmann, F. van Leeuwen, P. M. Marrese, M. A. Álvarez, A. Jean-Antoine Piccolo, A. F. Lanza, Alberto Vecchiato, Thomas Wevers, Caroline Soubiran, C. P. Murphy, A. M. Piersimoni, Alessandra Mastrobuono-Battisti, Peter G. Jonker, A. Sagristà Sellés, T. Roegiers, S. Marinoni, Johannes Sahlmann, Rene Andrae, P. Sartoretti, G. Altavilla, Raphael Guerra, F. X. Pineau, M. Segol, T. Prusti, J. J. González-Vidal, J. J. Aguado, N. R. Millar, A. Baudesson-Stella, Andrea Chiavassa, Laurent Chemin, C. Turon, H. Steidelmüller, Douglas J. Marshall, A. G. Butkevich, Alberto Riva, P. de Laverny, Simchon Faigler, Laurent Galluccio, A. Mora, P. Re Fiorentin, C. Ordénovic, J. F. Le Campion, A. Delgado, V. Sanchez Gimenez, M. David, G. Sadowski, R. L. Smart, A. Masip, Laia Casamiquela, R. Messineo, R. Mor, J. Bakker, C. Dolding, J. M. Martín-Fleitas, S. Diakite, Coryn A. L. Bailer-Jones, D. Souami, P. Madrero Pardo, Martin A. Barstow, David Teyssier, Ummi Abbas, Jesus Salgado, Paolo Tanga, A. Burlacu, O. Vanel, Ulrike Heiter, Daniel Hestroffer, Sebastian L. Hidalgo, H. E. Delgado, Alberto Krone-Martins, C. Robin, Kevin Benson, Christos Siopis, S. Managau, P. Burgess, Tomaz Zwitter, M. M. S. Marcos Santos, S. Cowell, J. L. Halbwachs, Xavier Luri, Antti Penttilä, R. Geyer, Minia Manteiga, Yassine Damerdji, Nigel Hambly, S. Bartolomé, J. Álvarez Cid-Fuentes, P. Osborne, J. Juaristi Campillo, Mark Taylor, Richard I. Anderson, Y. Le Fustec, Thierry Morel, T. Cornez, Krzysztof A. Rybicki, L. Pulone, N. Bauchet, Pierre Kervella, C. Zurbach, Alfred Castro-Ginard, Frédéric Arenou, P. Ramos, Robert G. Mann, Annie C. Robin, J. C. Segovia, M. Barros, Hector Canovas, D. L. Harrison, Y. Lasne, L. Noval, David Hobbs, E. F. del Peloso, P. Castro Sampol, Yves Fremat, F. De Luise, Daniel Michalik, P. J. Richards, L. Karbevska, N. Hładczuk, K. Kruszyńska, T. Boch, Sofia Randich, A. G. A. Brown, C. Pagani, L. Martin Polo, M. Ramos-Lerate, Krzysztof Nienartowicz, Eduard Masana, E. Racero, E. Fraile, Marc Audard, N. Robichon, Luciana Bianchi, G. Gracia-Abril, R. Santoveña, R. Haigron, N. Unger, Jérôme Berthier, Despina Hatzidimitriou, R. Gutiérrez-Sánchez, M. Fabrizio, I. Gonzalez-Santamaria, A. Dapergolas, P. Panuzzo, Benoit Carry, Francesca Figueras, R. Blomme, Elmé Breedt, D. Munoz, Diego Bossini, G. Busso, D. Katz, Simon Hodgkin, Ennio Poretti, N. Brouillet, Marco Castellani, Nicholas Rowell, Arnaud Siebert, M. Romero-Gómez, Shay Zucker, W. van Reeven, A. Kochoska, G. Giuffrida, Eva Sciacca, T. Carlucci, L. M. Sarro, M. I. Carnerero, Amina Helmi, D. Garabato, B. Holl, Michele Bellazzini, L. Rohrbasser, Teresa Antoja, J. Torra, Thomas Hilger, Pedro García-Lario, Gérard Jasniewicz, Enrique Solano, S. G. Baker, W. J. Cooper, F. Royer, S. Accart, George M. Seabroke, João Alves, Emese Plachy, C. Nicolas, Silvio Leccia, N. Cheek, Uwe Lammers, Ramachrisna Teixeira, Techniche Universtât Desden, Joseph Louis LAGRANGE (LAGRANGE), Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Lund Observatory, Lund University [Lund], Zentrum für astronomie, Universität Heidelberg [Heidelberg], Department of nuclear medicine, Haukeland University Hospital, University of Bergen (UiB)-University of Bergen (UiB), Merck Serono S.A [Geneva Research Center], Laboratoire d'études spatiales et d'instrumentation en astrophysique (LESIA (UMR_8109)), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut de Physique de Rennes (IPR), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Universität Heidelberg [Heidelberg] = Heidelberg University, Laboratoire d'études spatiales et d'instrumentation en astrophysique = Laboratory of Space Studies and Instrumentation in Astrophysics (LESIA), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS), Université Nice Sophia Antipolis (... - 2019) (UNS), Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Planetary-system research, Department of Physics, Particle Physics and Astrophysics, Gaia Collaboration, Unidad de Excelencia Científica María de Maeztu Instituto de Ciencias del Cosmos Universidad de Barcelona, MDM-2014-0369, Centro de Excelencia Científica Severo Ochoa, Instituto de Ciencias del Cosmos de la Universidad de Barcelona, SEV2015-0493, Deliste, J. B. [0000-0001-5844-9888], Sozzeti, A. [0000-0002-7504-365X], Forderung der wissenschaftlichen Forschung (FWF), Belgian federal Science Policy Office (BELSPO), Hertha Firnberg Programme, Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Comite Francais d'Evaluation de la Cooperation Universitaire et Scientifique avec le Bresil (COFECUB), National Natural Science Foundation of China (NSFC), China Scholarship Council (CSC), European Commission (EC), European Research Council (ERC), Hungarian National Research, Development, and Innovation Office (NKFIH), Science Foundation Ireland (SFI), Israel Science Foundation (ISF), Agenzia Spaziale Italiana (ASI), Istituto Nazionale di Astrofisica (INAF), Netherlands Research School for Astronomy (NOVA), Fundacao para a Ciencia e a Tecnologia (FCT), Agencia Estatal de Investigación (AEI), European Space Agency (ESA), Centre National D'Etudes Spatiales (CNES), Ministero dell'Istruzione, dell'Università e della Ricerca (MIUR), Narodowe Centrum Nauki (NCN), Slovenian Research Agency, Swedish National Space Agency (SNSA), United Kingdom Science and Technology Facilities Council (STFC), Universitat de Barcelona (UB), Generalitat de Catalunya, Xunta de Galicia, Universidad de Cantabria, ITA, European Commission, Ministerio de Ciencia, Innovación y Universidades (España), Ministerio de Economía y Competitividad (España), Astronomy, and Kapteyn Astronomical Institute

Subjects
Data Analysis, Solar System, Astronomy, kinematics and dynamics, virgo cluster, Astrophysics, 01 natural sciences, bar, Astronomi, astrofysik och kosmologi, large-magellanic-cloud, Methods, Astronomy, Astrophysics and Cosmology, 010303 astronomy & astrophysics, Physics, Astrophysics of Galaxies, [SDU.ASTR]Sciences of the Universe [physics]/Astrophysics [astro-ph], Astrophysics::Instrumentation and Methods for Astrophysics, Astrometry, VIRGO CLUSTER, Kinematics and Dynamics, Amplitude, kinematics, Physical Sciences, MILKY-WAY, astrometry, Galaxy: kinematics and dynamics, PROPER MOTION, Proper motion, perturbation, proper motions, reference systems, methods: data analysis, Astrophysics - Astrophysics of Galaxies, FOS: Physical sciences, Context (language use), proper motion, Astronomy & Astrophysics, MASS, Computer Science::Digital Libraries, Gravitational potential, Acceleration, Settore FIS/05 - Astronomia e Astrofisica, 0103 physical sciences, data analysis [methods], Vector spherical harmonics, KINEMATICS, distance, milky-way, Science & Technology, PERTURBATION, 010308 nuclear & particles physics, Astronomy and Astrophysics, kinematics and dynamics [Galaxy], 115 Astronomy, Space science, Physics::History of Physics, BAR, Galaxy, Space and Planetary Science, [SDU]Sciences of the Universe [physics], Astrophysics of Galaxies (astro-ph.GA), DISTANCE, mass, LARGE-MAGELLANIC-CLOUD
Abstract

Context. Gaia Early Data Release 3 (Gaia EDR3) provides accurate astrometry for about 1.6 million compact (QSO-like) extragalactic sources, 1.2 million of which have the best-quality five-parameter astrometric solutions., Aims. The proper motions of QSO-like sources are used to reveal a systematic pattern due to the acceleration of the solar systembarycentre with respect to the rest frame of the Universe. Apart from being an important scientific result by itself, the acceleration measured in this way is a good quality indicator of the Gaia astrometric solution., Methods. Theeffect of the acceleration was obtained as a part of the general expansion of the vector field of proper motions in vector spherical harmonics (VSH). Various versions of the VSH fit and various subsets of the sources were tried and compared to get the most consistent result and a realistic estimate of its uncertainty. Additional tests with the Gaia astrometric solution were used to get a better idea of the possible systematic errors in the estimate., Results. Our best estimate of the acceleration based on Gaia EDR3 is (2.32 +/- 0.16) x 10(-10) m s(-2) (or 7.33 +/- 0.51 km s(-1) Myr-1) towards alpha = 269.1 degrees +/- 5.4 degrees, delta = -31.6 degrees +/- 4.1 degrees, corresponding to a proper motion amplitude of 5.05 +/- 0.35 mu as yr(-1). This is in good agreement with the acceleration expected from current models of the Galactic gravitational potential. We expect that future Gaia data releases will provide estimates of the acceleration with uncertainties substantially below 0.1 mu as yr(-1).

Published
2020
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31. Retrofit Concept for Textile Production

Author

Susanne Franke, Felix Franke, and Ralph Riedel

Subjects
Production line, Industry 4.0, Computer science, Process (engineering), business.industry, 05 social sciences, 02 engineering and technology, Modular design, Manufacturing engineering, 020204 information systems, Scalability, Modular programming, 0202 electrical engineering, electronic engineering, information engineering, Production (economics), 0501 psychology and cognitive sciences, business, 050107 human factors, Digitization
Abstract

In production, an intelligent analysis of the data provided along the production line bears huge potential for increasing process efficiency and reducing production costs. The (continuous) collection of relevant data is a crucial precondition for every Industry 4.0 or smart technology. While new machines have internal controllers and sensors to meet those requirements, this is usually not the case for machines being already in use. Especially in the textile industry, it is often standard to keep old machines since the manufacturing methods themselves haven’t changed significantly over the past decades. Hence, the successful exploitation of digitalization advantages requires these companies to first develop and implement a digitization strategy. In this paper we present a concept which allows to develop modular, scalable, flexible solutions considering the whole digitization process from data acquisition to storage. The concept is complemented by a guideline for its application in industry. Experience from a prototypical application in a textile company is described. The concept enables companies to determine the various conditions and requirements for digitization, to analyze different possibilities and to deduce scenarios that lead to a solution for the effective utilization of Industry 4.0 technologies.

Published
2020

33. Automatic spike sorting for high-density microelectrode arrays

Author

Andreas Hierlemann, Felix Franke, Roland Diggelmann, and Michele Fiscella

Subjects
Neurons, 0301 basic medicine, Patch-Clamp Techniques, Mesocricetus, Quantitative Biology::Neurons and Cognition, Scale (ratio), Physiology, Computer science, General Neuroscience, Action Potentials, High density, Microarray Analysis, Article, 03 medical and health sciences, Microelectrode, Pre whitening, 030104 developmental biology, 0302 clinical medicine, Spike sorting, Cricetinae, Animals, Biological system, Microelectrodes, Algorithms, 030217 neurology & neurosurgery
Abstract

High-density microelectrode arrays can be used to record extracellular action potentials from hundreds to thousands of neurons simultaneously. Efficient spike sorters must be developed to cope with such large data volumes. Most existing spike sorting methods for single electrodes or small multielectrodes, however, suffer from the “curse of dimensionality” and cannot be directly applied to recordings with hundreds of electrodes. This holds particularly true for the standard reference spike sorting algorithm, principal component analysis-based feature extraction, followed by k-means or expectation maximization clustering, against which most spike sorters are evaluated. We present a spike sorting algorithm that circumvents the dimensionality problem by sorting local groups of electrodes independently with classical spike sorting approaches. It is scalable to any number of recording electrodes and well suited for parallel computing. The combination of data prewhitening before the principal component analysis-based extraction and a parameter-free clustering algorithm obviated the need for parameter adjustments. We evaluated its performance using surrogate data in which we systematically varied spike amplitudes and spike rates and that were generated by inserting template spikes into the voltage traces of real recordings. In a direct comparison, our algorithm could compete with existing state-of-the-art spike sorters in terms of sensitivity and precision, while parameter adjustment or manual cluster curation was not required. NEW & NOTEWORTHY We present an automatic spike sorting algorithm that combines three strategies to scale classical spike sorting techniques for high-density microelectrode arrays: 1) splitting the recording electrodes into small groups and sorting them independently; 2) clustering a subset of spikes and classifying the rest to limit computation time; and 3) prewhitening the spike waveforms to enable the use of parameter-free clustering. Finally, we combined these strategies into an automatic spike sorter that is competitive with state-of-the-art spike sorters.

Published
2018

35. Structures of Neural Correlation and How They Favor Coding

Author

Maksim Sevelev, Felix Franke, Rava Azeredo da Silveira, Andreas Hierlemann, Botond Roska, and Michele Fiscella

Subjects
Retinal Ganglion Cells, 0301 basic medicine, Computer science, Neuroscience(all), Models, Neurological, Population, Action Potentials, Retinal ganglion, Article, Correlation, 03 medical and health sciences, 0302 clinical medicine, Phenomenon, Animals, education, Communication, education.field_of_study, business.industry, General Neuroscience, Pattern recognition, Small population size, Nonlinear system, 030104 developmental biology, Female, Rabbits, Artificial intelligence, Nerve Net, business, Neural coding, 030217 neurology & neurosurgery, Coding (social sciences)
Abstract

The neural representation of information suffers from "noise"-the trial-to-trial variability in the response of neurons. The impact of correlated noise upon population coding has been debated, but a direct connection between theory and experiment remains tenuous. Here, we substantiate this connection and propose a refined theoretical picture. Using simultaneous recordings from a population of direction-selective retinal ganglion cells, we demonstrate that coding benefits from noise correlations. The effect is appreciable already in small populations, yet it is a collective phenomenon. Furthermore, the stimulus-dependent structure of correlation is key. We develop simple functional models that capture the stimulus-dependent statistics. We then use them to quantify the performance of population coding, which depends upon interplays of feature sensitivities and noise correlations in the population. Because favorable structures of correlation emerge robustly in circuits with noisy, nonlinear elements, they will arise and benefit coding beyond the confines of retina.

Published
2016
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37. Effective benchmarking of high-density MEA spike-sorters

Author

Roland Diggelmann, Andreas Hierlemann, and Felix Franke

Subjects
Retinal Ganglion Cells, 0303 health sciences, Quantitative Biology::Neurons and Cognition, Spike-sorting, high-density MEAs, Benchmarking, Ground-truth, Nonlinear Sciences::Cellular Automata and Lattice Gases, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, 030217 neurology & neurosurgery, 030304 developmental biology
Abstract

Frontiers in Cellular Neuroscience, ISSN:1662-5102, Conference Abstract: MEA Meeting 2018 | 11th International Meeting on Substrate Integrated Microelectrode Arrays

Published
2018

38. Acquisition of Bioelectrical Signals with Small Electrodes

Author

Andreas Hierlemann, Marie Engelene J. Obien, Vijay Viswam, Urs Frey, and Felix Franke

Subjects
Materials science, Attenuation, 020208 electrical & electronic engineering, 02 engineering and technology, Capacitance, Noise (electronics), Signal, Article, 03 medical and health sciences, Microelectrode, 0302 clinical medicine, Transmission (telecommunications), Electrode, 0202 electrical engineering, electronic engineering, information engineering, Electrical impedance, 030217 neurology & neurosurgery, Biomedical engineering
Abstract

Although the mechanisms of recording bioelectrical signals from different types of electrogenic cells (neurons, cardiac cells etc.) by means of planar metal electrodes have been extensively studied, the recording characteristics and conditions for very small electrode sizes are not yet established. Here, we present a combined experimental and computational approach to elucidate, how the electrode size influences the recorded signals, and how inherent properties of the electrode, such as impedance, noise, and transmission characteristics shape the signal. We demonstrate that good quality recordings can be achieved with electrode diameters of less than 10 μm, provided that impedance reduction measures have been implemented and provided that a set of requirements for signal amplification has been met.

Published
2018

41. Complexity Optimization and High-Throughput Low-Latency Hardware Implementation of a Multi-Electrode Spike-Sorting Algorithm

Author

Felix Franke, Jelena Dragas, Andreas Hierlemann, and David Jäckel

Subjects
Computational complexity theory, Computer science, Biomedical Engineering, Action Potentials, Sensitivity and Specificity, Article, Pattern Recognition, Automated, Electrocardiography, Internal Medicine, Latency (engineering), Electrodes, Neurons, Artificial neural network, business.industry, General Neuroscience, Rehabilitation, Reproducibility of Results, Signal Processing, Computer-Assisted, Equipment Design, Chip, Equipment Failure Analysis, Spike sorting, Electrode, FPGA, High throughput, Low latency, Multi-electrode, Real-time, Nerve Net, business, Algorithm, Algorithms, Computer hardware, Data transmission
Abstract

Reliable real-time low-latency spike sorting with large data throughput is essential for studies of neural network dynamics and for brain-machine interfaces (BMIs), in which the stimulation of neural networks is based on the networks' most recent activity. However, the majority of existing multi-electrode spike-sorting algorithms are unsuited for processing high quantities of simultaneously recorded data. Recording from large neuronal networks using large high-density electrode sets (thousands of electrodes) imposes high demands on the data-processing hardware regarding computational complexity and data transmission bandwidth; this, in turn, entails demanding requirements in terms of chip area, memory resources and processing latency. This paper presents computational complexity optimization techniques, which facilitate the use of spike-sorting algorithms in large multi-electrode-based recording systems. The techniques are then applied to a previously published algorithm, on its own, unsuited for large electrode set recordings. Further, a real-time low-latency high-performance VLSI hardware architecture of the modified algorithm is presented, featuring a folded structure capable of processing the activity of hundreds of neurons simultaneously. The hardware is reconfigurable “on-the-fly” and adaptable to the nonstationarities of neuronal recordings. By transmitting exclusively spike time stamps and/or spike waveforms, its real-time processing offers the possibility of data bandwidth and data storage reduction.

Published
2015

43. Combination of High-density Microelectrode Array and Patch Clamp Recordings to Enable Studies of Multisynaptic Integration

Author

Thomas L. Russell, Douglas J. Bakkum, David Jäckel, Andreas Hierlemann, Urs Frey, Milos Radivojevic, Felix Franke, and Jan Müller

Subjects
0301 basic medicine, Patch-Clamp Techniques, Computer science, Science, Action Potentials, Local field potential, Bioinformatics, Inhibitory postsynaptic potential, Article, Synapse, 03 medical and health sciences, 0302 clinical medicine, Postsynaptic potential, Neuroplasticity, medicine, Animals, Patch clamp, Rats, Wistar, Neurons, Neuronal Plasticity, Multidisciplinary, Multielectrode array, Microarray Analysis, Rats, Microelectrode, 030104 developmental biology, medicine.anatomical_structure, Synapses, Natural sciences, Synaptic plasticity, Excitatory postsynaptic potential, Medicine, ddc:500, Neuron, Microelectrodes, Neuroscience, FOS: Natural sciences, 030217 neurology & neurosurgery
Abstract

We present a novel, all-electric approach to record and to precisely control the activity of tens of individual presynaptic neurons. The method allows for parallel mapping of the efficacy of multiple synapses and of the resulting dynamics of postsynaptic neurons in a cortical culture. For the measurements, we combine an extracellular high-density microelectrode array, featuring 11’000 electrodes for extracellular recording and stimulation, with intracellular patch-clamp recording. We are able to identify the contributions of individual presynaptic neurons - including inhibitory and excitatory synaptic inputs - to postsynaptic potentials, which enables us to study dendritic integration. Since the electrical stimuli can be controlled at microsecond resolution, our method enables to evoke action potentials at tens of presynaptic cells in precisely orchestrated sequences of high reliability and minimum jitter. We demonstrate the potential of this method by evoking short- and long-term synaptic plasticity through manipulation of multiple synaptic inputs to a specific neuron., Scientific Reports, 7, ISSN:2045-2322

Published
2017

44. Congenital Nystagmus Gene FRMD7 Is Necessary for Establishing a Neuronal Circuit Asymmetry for Direction Selectivity

Author

Jan Müller, János Németh, Antonia Drinnenberg, Federico Esposti, Arnold Szabo, Zoltán Zsolt Nagy, Josephine Jüttner, Stuart Trenholm, Francis L. Munier, Francisco Cordoba, Botond Roska, Felix Franke, Andreas Hierlemann, Keisuke Yonehara, Michele Fiscella, Akos Kusnyerik, Brigitte Gross Scherf, Jacek Krol, Yonehara, K, Fiscella, M, Drinnenberg, A, Esposti, Federico, Trenholm, S, Krol, J, Franke, F, Gross Scherf, B, Kusnyerik, A, Müller, J, Szabo, A, Jüttnern, J, Cordoba, F, Police Reddy, A, Németh, J, Zsolt Nagy, Z, Munier, F, Hierlemann, A, and Roska, B.

Subjects
Retinal Ganglion Cells, 0301 basic medicine, Interneuron, Neuroscience(all), Motion Perception, Action Potentials, Neural Inhibition, Mice, Transgenic, Nystagmus, Biology, Visual system, Inhibitory postsynaptic potential, Retinal ganglion, Article, Retina, 03 medical and health sciences, medicine, Animals, Visual Pathways, General Neuroscience, Optokinetic reflex, Cytoskeletal Proteins, Amacrine Cells, 030104 developmental biology, medicine.anatomical_structure, Synapses, sense organs, Nerve Net, medicine.symptom, Nystagmus, Congenital, Neuroscience, Photic Stimulation
Abstract

Summary Neuronal circuit asymmetries are important components of brain circuits, but the molecular pathways leading to their establishment remain unknown. Here we found that the mutation of FRMD7, a gene that is defective in human congenital nystagmus, leads to the selective loss of the horizontal optokinetic reflex in mice, as it does in humans. This is accompanied by the selective loss of horizontal direction selectivity in retinal ganglion cells and the transition from asymmetric to symmetric inhibitory input to horizontal direction-selective ganglion cells. In wild-type retinas, we found FRMD7 specifically expressed in starburst amacrine cells, the interneuron type that provides asymmetric inhibition to direction-selective retinal ganglion cells. This work identifies FRMD7 as a key regulator in establishing a neuronal circuit asymmetry, and it suggests the involvement of a specific inhibitory neuron type in the pathophysiology of a neurological disease. Video Abstract, Highlights • FRMD7 is required for the horizontal optokinetic reflex in mice as in humans • Horizontal direction selectivity is lost in the retina of FRMD7 mutant mice • Asymmetry of inhibitory inputs to horizontal DS cells is lost in FRMD7 mutant mice • FRMD7 is expressed in ChAT-expressing cells in the retina of mice and primates, Yonehara et al. show that FRMD7, a gene that is defective in human congenital nystagmus, is required in the mouse retina to establish spatially asymmetric inhibitory inputs from starburst cells to horizontal direction-selective ganglion cells.

Published
2016
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45. Time-lapse electrical impedance spectroscopy for monitoring the cell cycle of single immobilized S. pombe cells

Author

Andreas Hierlemann, Niels Haandbæk, Zhen Zhu, Felix Franke, Fabian Rudolf, and Olivier Frey

Subjects
Materials science, Finite Element Analysis, Microfluidics, 02 engineering and technology, Time-Lapse Imaging, 01 natural sciences, Article, Schizosaccharomyces, Computer Simulation, Electrical impedance, Cell Proliferation, Cytokinesis, Cell Nucleus, Multidisciplinary, Lab-on-a-chip, biology, Cell growth, Cell Cycle, 010401 analytical chemistry, Biomedical engineering, Cells, Immobilized, Cell cycle, 021001 nanoscience & nanotechnology, biology.organism_classification, 0104 chemical sciences, Dielectric spectroscopy, Cell biology, Dielectric Spectroscopy, Schizosaccharomyces pombe, 0210 nano-technology, Biological system
Abstract

As a complement and alternative to optical methods, wide-band electrical impedance spectroscopy (EIS) enables multi-parameter, label-free and real-time detection of cellular and subcellular features. We report on a microfluidics-based system designed to reliably capture single rod-shaped Schizosaccharomyces pombe cells by applying suction through orifices in a channel wall. The system enables subsequent culturing of immobilized cells in an upright position, while dynamic changes in cell-cycle state and morphology were continuously monitored through EIS over a broad frequency range. Besides measuring cell growth, clear impedance signals for nuclear division have been obtained. The EIS system has been characterized with respect to sensitivity and detection limits. The spatial resolution in measuring cell length was 0.25 μm, which corresponds to approximately a 5-min interval of cell growth under standard conditions. The comprehensive impedance data sets were also used to determine the occurrence of nuclear division and cytokinesis. The obtained results have been validated through concurrent confocal imaging and plausibilized through comparison with finite-element modeling data. The possibility to monitor cellular and intracellular features of single S. pombe cells during the cell cycle at high spatiotemporal resolution renders the presented microfluidics-based EIS system a suitable tool for dynamic single-cell investigations., Scientific Reports, 5, ISSN:2045-2322

Published
2015
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47. How Diverse Retinal Functions Arise from Feedback at the First Visual Synapse

Author

Antonia Drinnenberg, Rava Azeredo da Silveira, Josephine Jüttner, Felix Franke, Andreas Hierlemann, Péter Hantz, Rei K. Morikawa, Daniel Hillier, Botond Roska, Friedrich Miescher Institute for Biomedical Research (FMI), Novartis Research Foundation, Department of Biosystems Science and Engineering [ETH Zürich] (D-BSSE), Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich), Laboratoire de Physique Statistique de l'ENS (LPS), Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), and Princeton Neuroscience Institute [Princeton]

Subjects
Retinal Ganglion Cells, 0301 basic medicine, Retinal Bipolar Cells, Cell type, Interneuron, [SDV]Life Sciences [q-bio], Models, Neurological, Retinal Horizontal Cells, Biology, Feedback, Synapse, Mice, 03 medical and health sciences, chemistry.chemical_compound, Interneurons, medicine, Animals, Vision, Ocular, Retina, General Neuroscience, Retinal, Ganglion, Brain region, 030104 developmental biology, medicine.anatomical_structure, chemistry, Mouse Retina, Synapses, Calcium, Neuroscience, Photoreceptor Cells, Vertebrate
Abstract

International audience; Many brain regions contain local interneurons of distinct types. How does an interneuron type contribute to the input-output transformations of a given brain region? We addressed this question in the mouse retina by chemogenetically perturbing horizontal cells, an interneuron type providing feedback at the first visual synapse, while monitoring the light-driven spiking activity in thousands of ganglion cells, the retinal output neurons. We uncovered six reversible perturbation-induced effects in the response dynamics and response range of ganglion cells. The effects were enhancing or suppressive, occurred in different response epochs, and depended on the ganglion cell type. A computational model of the retinal circuitry reproduced all perturbation-induced effects and led us to assign specific functions to horizontal cells with respect to different ganglion cell types. Our combined experimental and theoretical work reveals how a single interneuron type can differentially shape the dynamical properties of distinct output channels of a brain region.

Published
2018

48. Spike Sorting of Synchronous Spikes from Local Neuron Ensembles

Author

Robert Pröpper, Klaus Obermayer, Matthias H. J. Munk, Felix Franke, Jörg R. P. Geiger, Philipp Meier, and Henrik Alle

Subjects
Patch-Clamp Techniques, Physiology, Computer science, Models, Neurological, Action Potentials, Prefrontal Cortex, Neuropsychological Tests, Hippocampus, Tissue Culture Techniques, medicine, Animals, Computer Simulation, Patch clamp, Rats, Wistar, Prefrontal cortex, Tetrode (biology), Neurons, General Neuroscience, Template matching, Signal Processing, Computer-Assisted, Filter (signal processing), Electric Stimulation, Memory, Short-Term, medicine.anatomical_structure, Spike sorting, Visual Perception, Innovative Methodology, Macaca, Spike (software development), Neuron, Neuroscience
Abstract

Synchronous spike discharge of cortical neurons is thought to be a fingerprint of neuronal cooperativity. Because neighboring neurons are more densely connected to one another than neurons that are located further apart, near-synchronous spike discharge can be expected to be prevalent and it might provide an important basis for cortical computations. Using microelectrodes to record local groups of neurons does not allow for the reliable separation of synchronous spikes from different cells, because available spike sorting algorithms cannot correctly resolve the temporally overlapping waveforms. We show that high spike sorting performance of in vivo recordings, including overlapping spikes, can be achieved with a recently developed filter-based template matching procedure. Using tetrodes with a three-dimensional structure, we demonstrate with simulated data and ground truth in vitro data, obtained by dual intracellular recording of two neurons located next to a tetrode, that the spike sorting of synchronous spikes can be as successful as the spike sorting of nonoverlapping spikes and that the spatial information provided by multielectrodes greatly reduces the error rates. We apply the method to tetrode recordings from the prefrontal cortex of behaving primates, and we show that overlapping spikes can be identified and assigned to individual neurons to study synchronous activity in local groups of neurons.

Published
2015

49. Highly integrated CMOS microsystems to interface with neurons at subcellular resolution

Author

Jan Müller, Felix Franke, Douglas J. Bakkum, and Andreas Hierlemann

Subjects
0303 health sciences, Engineering, business.industry, Interface (computing), Article, 03 medical and health sciences, 0302 clinical medicine, CMOS, nervous system, Microsystem, Electronic engineering, Biological neural network, Premovement neuronal activity, Extended time, business, Neuroscience, 030217 neurology & neurosurgery, 030304 developmental biology
Abstract

CMOS high-density transducer arrays enable fundamentally new neuroscientific insights through, e.g., facilitating investigation of axonal signaling characteristics, with the "axonal" side of neuronal activity being largely inaccessible to established methods. They also enable high-throughput monitoring of potentially all action potentials in a larger neuronal network (> 1000 neurons) over extended time to see developmental effects or effects of disturbances. Applications include research in neural diseases and pharmacology., 2015 IEEE International Electron Devices Meeting (IEDM), ISBN:978-1-4673-9894-7, ISBN:978-1-4673-9893-0, ISBN:978-1-4673-9895-4

Published
2015

50. ViSAPy: A Python tool for biophysics-based generation of virtual spiking activity for evaluation of spike-sorting algorithms

Author

Christina Sørensen, Marianne Fyhn, Torbjørn V. Ness, Amir Khosrowshahi, Espen Hagen, Gaute T. Einevoll, Felix Franke, and Torkel Hafting

Subjects
Computer science, Neuroscience(all), Models, Neurological, Biophysics, Action Potentials, Retina, Mice, Extracellular potential, Animals, Waveform, Computer Simulation, ddc:610, Visual Cortex, computer.programming_language, Neurons, Principal Component Analysis, General Neuroscience, Signal Processing, Computer-Assisted, Multielectrode array, Benchmarking, Open source software, Python (programming language), Brain Waves, Mice, Inbred C57BL, Spike sorting, Synapses, Benchmark data, Microelectrodes, Algorithm, computer
Abstract

Background New, silicon-based multielectrodes comprising hundreds or more electrode contacts offer the possibility to record spike trains from thousands of neurons simultaneously. This potential cannot be realized unless accurate, reliable automated methods for spike sorting are developed, in turn requiring benchmarking data sets with known ground-truth spike times. New method We here present a general simulation tool for computing benchmarking data for evaluation of spike-sorting algorithms entitled ViSAPy (Virtual Spiking Activity in Python) . The tool is based on a well-established biophysical forward-modeling scheme and is implemented as a Python package built on top of the neuronal simulator NEURON and the Python tool LFPy . Results ViSAPy allows for arbitrary combinations of multicompartmental neuron models and geometries of recording multielectrodes. Three example benchmarking data sets are generated, i.e., tetrode and polytrode data mimicking in vivo cortical recordings and microelectrode array (MEA) recordings of in vitro activity in salamander retinas. The synthesized example benchmarking data mimics salient features of typical experimental recordings, for example, spike waveforms depending on interspike interval. Comparison with existing methods ViSAPy goes beyond existing methods as it includes biologically realistic model noise, synaptic activation by recurrent spiking networks, finite-sized electrode contacts, and allows for inhomogeneous electrical conductivities. ViSAPy is optimized to allow for generation of long time series of benchmarking data, spanning minutes of biological time, by parallel execution on multi-core computers. Conclusion ViSAPy is an open-ended tool as it can be generalized to produce benchmarking data or arbitrary recording-electrode geometries and with various levels of complexity.

Published
2015

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