7 results on '"Felipe Immich"'
Search Results
2. Evaluation of Antimicrobial Properties, Cell Viability, and Metalloproteinase Activity of Bioceramic Endodontic Materials Used in Vital Pulp Therapy
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Felipe Immich, Durvalino de Oliveira, Juliana Silva Ribeiro de Andrade, Andressa da Silva Barboza, Carlos Enrique Cuevas-Suárez, Adriana Fernandes da Silva, Wellington Luiz de Oliveira da Rosa, Álvaro Henrique Borges, Neftali Lenin Villarreal Carreno, Evandro Piva, and Rafael Guerra Lund
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endodontics ,vital pulp therapy ,dental materials ,root canal therapy ,Biotechnology ,TP248.13-248.65 ,Medicine (General) ,R5-920 - Abstract
This study aimed to evaluate the antimicrobial properties, cell viability, and matrix metalloproteinase (MMP) inhibition capacity of several endodontic materials aimed at vital pulp therapy: Pro Root MTA®, EndoSequence®, Biodentine®, MTA Angelus®, TheraCal LC®, and BioC Repair®. The materials were prepared according to the manufacturer’s instructions. Antimicrobial tests were conducted using a microcosm biofilm model, cell viability was assessed using murine fibroblasts (L929), and MMP activity was analyzed through electrophoresis. The results showed that BioC Repair®, Biodentine®, and EndoSequence® exhibited similar antimicrobial properties, while MTA Angelus® and ProRoot MTA® had inferior results but were comparable to each other. In terms of cell viability, no significant differences were observed among the materials. EndoSequence® demonstrated the highest MMP inhibition capacity. In conclusion, BioC Repair®, Biodentine®, EndoSequence®, and TheraCal® showed better antimicrobial properties among the tested materials. The materials did not exhibit significant differences in terms of cytotoxicity. However, EndoSequence® displayed superior MMP inhibition capacity.
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- 2024
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3. Bioactivity Potential of Bioceramic-Based Root Canal Sealers: A Scoping Review
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Mauro Schmitz Estivalet, Lucas Peixoto de Araújo, Felipe Immich, Adriana Fernandes da Silva, Nadia de Souza Ferreira, Wellington Luiz de Oliveira da Rosa, and Evandro Piva
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calcium-silicate ,bioactivity ,bioceramics ,root canal sealer ,endodontics ,scoping review ,Science - Abstract
Introduction: Bioceramic-based root canal sealers are novel materials with a bioactivity potential that stands out compared with conventional root canal sealers. However, the term bioactivity may be overused and is often misunderstood. Hence, the objective of this study was to synthesize and map key concepts related to the bioactivity analysis of bioceramic-based root canal sealers. Methods: The present scoping review is reported in accordance with the PRISMA-ScR Statement and is registered in the Open Science Framework. Two blinded reviewers carried out a comprehensive search in six databases up to January 10th, 2022: MEDLINE, Scopus, Embase, Web of Science, Cochrane Library, and Lilacs/BBO. Eligibility was considered for in vitro and in vivo studies that evaluated the bioactivity potential of bioceramic-based root canal sealers. Results: A total of 53 studies were included in the qualitative synthesis. In vitro bioactivity was evaluated through the mineralization potential, formation of carbonated apatite on the surface, and the gene expression related to proteins involved in the mineralization process. Meanwhile, for in vivo studies, staining techniques associated with immunohistochemical tests were mainly used to detect mineralization on the material–host tissue interface. Conclusions: According to the methodology used, the most prevalent methods to assess bioactivity in acellular form were the immersion of the material in Hank’s balanced salt solution, followed by surface observation with scanning electron microscopy and energy dispersive X-ray. In cell cultures, the chosen method was usually Alizarin Red staining, followed by the evaluation of alkaline phosphatase enzymatic activity and the use of molecular biology tests.
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- 2022
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4. Repair of aged restorations made in direct resin composite – A Systematic Review
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Marcieli Dias Furtado, Felipe Immich, Wellington Luiz de Oliveira da Rosa, Evandro Piva, and Adriana Fernandes da Silva
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Biomaterials ,Polymers and Plastics ,General Chemical Engineering - Abstract
Objective: to evaluate the different bonding strategies for repairing aged resin composite restorations. Materials and Methods: The review was reported according to PRISMA Statement and registered in the Open Science Framework (DOI:10.17605/OSF.IO/WZTGS). Two reviewers performed a literature search across Embase (758), Pubmed (1244), Scopus (4300), The Cochrane library (128), and Web of Science (2538) databases. The risk of bias was assessed according to random sequence generation, blinding of outcome assessment, incomplete outcome data, selective reporting, coefficient of variation, and other bias. Results: Forty-four in vitro studies with different repair strategies on aged resin composite substrates were included from 1990 up to July 2022 which evaluated superficial treatment using shear, flexural, tensile, and bond strength tests. The most frequent treatments were diamond bur and air abrasion. Meta-analysis showed an overall effect significant to diamond bur (shear test; p = 0.02), air abrasion (shear; p = 0.009; flexural, p = 0.003; tensile; p = 0.004 tests), and to phosphoric acid (tensile test, p < 0.00001). Conclusions: Within the limitations of this study, strategies for improving bond to aged composites may consider better bond using air abrasion or diamond burs, and surface etching with phosphoric followed by the application of an adhesive system. Clinical Significance: This review presents the best treatments for performing the repair on aged resin composite, as guidance for clinical studies to improve emphasis on these findings, with the aim of creating a protocol that will enable dentists to promote minimally invasive treatments. Clinical Significance: This review presents the best treatments for performing repair with resin composite, as guidance for clinical studies to improve emphasis on these findings, with the aim of creating a protocol that will enable dentists to promote minimally invasive treatments.
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- 2022
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5. Photosensitive resins used in additive manufacturing for oral application in dentistry: A scoping review from lab to clinic
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Tiago Machado Da Silva, Felipe Immich, Tiago Schlindvein De Araujo, Rafael Guerra Lund, Adriana Fernandes Da Silva, Evandro Piva, and Wellington Luiz De Oliveira Da Rosa
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Biomaterials ,Mechanics of Materials ,Biomedical Engineering - Published
- 2023
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6. Effect of an Intraorifice Barrier on Endodontically Treated Teeth: A Systematic Review and Meta-Analysis of In Vitro Studies
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Lucas Peixoto de Araújo, Wellington Luiz de Oliveira da Rosa, Tiago Schlindvein de Araujo, Felipe Immich, Adriana Fernandes da Silva, and Evando Piva
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Tooth, Nonvital ,General Immunology and Microbiology ,Glass Ionomer Cements ,Medicine ,Humans ,General Medicine ,Review Article ,General Biochemistry, Genetics and Molecular Biology - Abstract
The main cause of unsuccess in endodontically treated teeth (ETT) is due to bacterial recontamination. The placement of an intraorifice barrier (IOB) has been proposed for preventing this event in cases that the restoration is in an inadequate condition, enhancing the possibilities for predictable long-term success in endodontic therapy. Objectives. To evaluate through a systematic review and meta-analysis if it would be necessary to place an IOB in ETT. Materials and Methods. The present review is in accordance with the PRISMA 2020 Statement and is registered in the Open Science Framework. Two blinded reviewers carried out a comprehensive search in four databases up to July 10th, 2021: MEDLINE, Scopus, Embase, and Web of Science. Eligible studies were the ones which evaluated the use of an IOB in ETT in reducing microleakage with any material of choice and with any methods employed. Only in vitro studies published in English were included. Results. A total of thirty in vitro studies were included in the qualitative synthesis, and seven of those were included in the quantitative analyses evaluating the following materials: bioceramic cement, glass-ionomer cement (GIC), and resin-based composite (RBC). Most of the included studies placed an IOB at a 3 mm depth. Reduction in microleakage was observed when an IOB was placed, regardless of the material employed ( p ≤ 0.01 ). Among the materials, GIC and RBC performed similarly ( p > 0.05 ), with the bioceramic subgroup being statistically superior to the GIC subgroup ( p ≤ 0.05 ). Conclusions. Although well-designed randomized clinical trials are required, the placement of an intraorifice barrier can significantly reduce microleakage in endodontically treated teeth, and the use of bioceramics as IOB seems to be the best available material for this purpose.
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- 2022
7. ANESTESIA EM ENDODONTIA
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null Luiz Paulo Nikraszewicz de Souza, null Camila Moreira Marques, null Felipe Immich, null Laura Lourenço Morel, null Luiza Hiara de Moraes Kolton, null Juliana Monteiro Pereira, null Ali Kalil Ibrahim, and Ezilmara Leonor Rolim de Sousa
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- 2021
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