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1. 2024 Recommendations on the Optimal Use of Lipid-Lowering Therapy in Established Atherosclerotic Cardiovascular Disease and Following Acute Coronary Syndromes: A Position Paper of the International Lipid Expert Panel (ILEP)

Author

Banach, Maciej, Reiner, Željko, Surma, Stanisław, Bajraktari, Gani, Bielecka-Dabrowa, Agata, Bunc, Matjaz, Bytyçi, Ibadete, Ceska, Richard, Cicero, Arrigo F. G., Dudek, Dariusz, Dyrbuś, Krzysztof, Fedacko, Jan, Fras, Zlatko, Gaita, Dan, Gavish, Dov, Gierlotka, Marek, Gil, Robert, Gouni-Berthold, Ioanna, Jankowski, Piotr, Járai, Zoltán, Jóźwiak, Jacek, Katsiki, Niki, Latkovskis, Gustavs, Magda, Stefania Lucia, Margetic, Eduard, Margoczy, Roman, Mitchenko, Olena, Durak-Nalbantic, Azra, Ostadal, Petr, Paragh, Gyorgy, Petrulioniene, Zaneta, Paneni, Francesco, Pećin, Ivan, Pella, Daniel, Postadzhiyan, Arman, Stoian, Anca Pantea, Trbusic, Matias, Udroiu, Cristian Alexandru, Viigimaa, Margus, Vinereanu, Dragos, Vlachopoulos, Charalambos, Vrablik, Michal, Vulic, Dusko, and Penson, Peter E.

Published
2024
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2. Effects of Molecular Hydrogen in the Pathophysiology and Management of Metabolic and Non-communicable Diseases

Author

Singh, Ram B., Tarnava, Alex, Fedacko, Jan, Fatima, Gizal, Rupee, Sunil, Sumbalova, Zuzana, Dhalla, Naranjan S., Series Editor, Bolli, Roberto, Editorial Board Member, Goyal, Ramesh, Editorial Board Member, Kartha, Chandrasekharan, Editorial Board Member, Kirshenbaum, Lorrie, Editorial Board Member, Makino, Naoki, Editorial Board Member, Mehta, Jawahar L. L., Editorial Board Member, Ostadal, Bohuslav, Editorial Board Member, Pierce, Grant N., Editorial Board Member, Slezak, Jan, Editorial Board Member, Varro, Andras, Editorial Board Member, Werdan, Karl, Editorial Board Member, Weglicki, William B., Editorial Board Member, and Kura, Branislav, editor

Published
2024
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3. Association of cardiovascular and metabolic diseases with risk of dementia in the urban population of North India

Author

Singh Ram B., Wilczynska Agnieszka, Fedacko Jan, Horiuchi Rie, Takahashi Toru, Fatima Ghizal, Ismail Manal, Magomedova Aminat, Moshiri Arsha, and Moshiri Mahmood

Subjects
western diet, sedentary behaviour, mastication, cardiovascular diseases, Medicine
Abstract

Background/Aim: Dementia has become a public health problem due to its association with biological risk factors; obesity, diabetes, hypertension and hypercholesterolaemia. Most of these risk factors, appear to be associated with dementia as well as with risk of coronary artery diseases (CADs) and stroke. This study aimed to find out the association of biological risk factors with cognitive impairment and dementia. Methods: Cross-sectional survey in a hospital was performed. After written informed consent and approval from hospital ethic committee, all subjects (n = 2002) above 25 years of age (1016 males and 986 females) were randomly selected and recruited from urban population of Moradabad, North India. Clinical data and risk factors were recorded with the help of case record form and validated questionnaires. Assessment of cognitive decline and dementia was made by Singh's memory function rating scale and biological risk factors by physical examination, sphygmomanometer and electrocardiography. The association of biological risk factors with dementia was calculated by multivariate logistic regression analysis after adjustment of age and sex. Results: Obesity, diabetes, hypertension, CAD and hypercholesterolemia were highly prevalent independent risk factors among patients with dementia. Multivariate logistic regression analysis showed that regardless of age and body mass index, diabetes mellitus and CAD were highly significant (p < 0.001) risk factors of dementia. Hypertension and family history of dementia were weakly but significantly(p < 0.05) associated with dementia. Conclusion: It is possible that increased frequency of obesity, diabetes, hypertension and CAD may increase the risk of dementia in an ageing population. Prevention and control of these biological risk factors may cause decline in the risk of dementia.

Published
2023

5. Western diets and risk of non-communicable diseases

Author

Fedacko, Jan, primary, Takahashi, Toru, additional, Singh, Ram B., additional, Pella, Dominik, additional, Chibisov, Sergey, additional, Hristova, Krasimira, additional, Pella, Daniel, additional, Elkilany, Galal Nagib, additional, Juneja, Lekh Raj, additional, Behl, Shalini, additional, Singh, Jaipaul, additional, and Smail, Manal M.A., additional

Published
2022
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8. Nutritional modulators of preconceptional and perinatal factors for primordial prevention of non-communicable diseases: the role of a millet-based diet rich in functional foods

Author

Singh, Ram B., primary, Fedacko, Jan, additional, Mojto, Viliam, additional, Horiuchi, Rie, additional, Dewi, Mira, additional, Watanabe, Shaw, additional, Tiwari, Poonam, additional, Singh, Mukta, additional, Sharma, Divyank, additional, and Sulaeman, Ahmad, additional

Published
2022
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15. Amalgamation of Circadian Clock Gene with Incidence of Myocardial Infa rction.

Author

Fatima, Ghizal, Parvez, Sidrah, Tuomainen, Petri, Fedacko, Jan, Kazmi, Danish Hasan, and Nagib Elkilany, Galal E.

Subjects
MYOCARDIAL infarction, TROPONIN, GENOMICS, BODY mass index, GENETIC markers, HYPERTENSION, LOGISTIC regression analysis, KRUSKAL-Wallis Test, CARDIOVASCULAR diseases risk factors, DNA, LYMPHOCYTES, REVERSE transcriptase polymerase chain reaction, CHI-squared test, MANN Whitney U Test, GENETIC polymorphisms, GENETIC variation, CIRCADIAN rhythms, DATA analysis software, GENOTYPES, SINGLE nucleotide polymorphisms, OBESITY, ALLELES
Abstract

Objectives: The present study included 40 participants to investigate the association of circadian locomotor output cycles kaput (CLOCK) rs4580704 polymorphism with myocardial infarction (MI) cases. Materials and Methods: In this study, we enrolled 20 male and 20 female cases with MI. Genomic DNA extraction was done from lymphocytes using conventional techniques, employing the QIAamp DNA Blood Mini Kit (Qiagen, Hilden, Germany) from lymphocytes. Genotyping was conducted through TaqMan singlenucleotide polymorphism genotyping assays, employing real-time polymerase chain reaction (PCR) on a 7500 Real-Time PCR System (Applied Biosystems, Foster City, CA, USA). This streamlined approach ensures accurate and efficient analysis of genetic markers associated with MI across gender groups. Results: The study revealed significant associations between body mass index (BMI), hypertension, obesity, current smoking, and type 2 diabetes among both male and female MI patients. However, age, systolic blood pressure (SBP), and diastolic blood pressure (DBP) did not exhibit significant differences between genders. Analysis of CLOCK rs4580704 polymorphism indicated no variance in genotype and allele frequencies between male and female MI patients. When considering both genders, CLOCK rs4580704 polymorphism was significantly associated with BMI, hypertension, obesity, current smoking, and type 2 diabetes (P = 0.02, P = 0.02, P = 0.04, and P = 0.02, respectively). Nevertheless, logistic regression analysis showed no significant differences among MI cases across the various models of CLOCK rs4580704 polymorphism. Conclusion: No significant association was found between CLOCK rs4580704 polymorphism and MI in both genders. However, significant links were identified between this polymorphism and various cardiovascular risk factors including BMI, SBP, DBP, hypertension, obesity, current smoking, and type 2 diabetes in MI cases. These findings underscore the potential influence of CLOCK rs4580704 polymorphism on cardiovascular risk profiles among individuals with MI. [ABSTRACT FROM AUTHOR]

Published
2024
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16. PRE-HEART FAILURE IN THE LIGHT OF 2D AND 3D SPECKLE TRACKING ECHOCARDIOGRAPHY: A COMPREHENSIVE REVIEW

Author

SINGH, R.B, primary, Elkilany, Galal, additional, Fedacko, Jan, additional, Sozzi, Fabiola, additional, Hristova, Krasimira, additional, Fatima, Ghizal, additional, Pella, Daniel, additional, Cornelissen, Germaine, additional, Isaza, Adrian, additional, Pella, Dominik, additional, Singh, Jaipaul, additional, Carugo, Stefano, additional, and Nanda, Navin C., additional

Published
2024
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17. Effects of Molecular Hydrogen in the Pathophysiology and Management of Cardiovascular and Metabolic Diseases

Author

Singh, Ram B., primary, Sumbalova, Zuzana, primary, Fatima, Ghizal, primary, Mojto, Viliam, primary, Fedacko, Jan, primary, Tarnava, Alex, primary, Pokotylo, Oleg, primary, Gvozdjakova, Anna, primary, Ferenczyova, Kristina, primary, Vlkovicova, Jana, primary, Kura, Branislav, primary, Kalocayova, Barbora, primary, Zenuch, Pavol, primary, and Slezak, Jan, primary

Published
2024
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31. Chapter 1 - History of medicine from ancient times to present

Author

Singh, Ram B., Sharma, J.P., Elkilany, Galaleldin Nagib, Fedacko, Jan, Hristova, Krasimira, Kabbash, Ibrahim, El-Shafey, Mohammad Ismaeil, Omidvar, Shabnam, Shahrajabian, Hseam, Khatibi, Mojgan, Zadigan, Sara Sarrafi, Dwivedi, Shridhar, Smail, Manal M.A., Tripathi, Kamala K., Singh, R.G., Singal, Pawan K., Tyagi, Suresh, Motamedian, Hosna, and Pella, Daniel

Published
2024
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36. Evolutionary Diet and Evolution of Man

Author

Juneja, Lekh R., primary, Wilczynska, Agnieszka, additional, Singh, Ram B., additional, Takahashi, Toru, additional, Pella, Dominik, additional, Chibisov, Sergey, additional, Abramova, Maria, additional, Hristova, Krasimira, additional, Fedacko, Jan, additional, Pella, Daniel, additional, and Wilson, Douglas W., additional

Published
2019
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39. List of Contributors

Author

Abramova, Maria, primary, Basu, Saikat K., additional, Beppu, Shigeru, additional, Bernardo, Maria Alexandra Sardinha, additional, Bhardwaj, Kshitij, additional, Buttar, Harpal S., additional, Cetzal-Ix, William, additional, Charkrabarti, Tanya, additional, Chauhan, Anil K., additional, Chaves, Hilton, additional, Chibisov, Sergey, additional, Cornelissen, Germaine, additional, Daliri, Eric Banan-Mwine, additional, Dass, J. Febin Prabhu, additional, De, Amit Krishna, additional, De, Minakshi, additional, Elkilany, Galal Nagib, additional, Endo, Keio, additional, Fedacko, Jan, additional, Fikri, Al Mukhlas, additional, Ghorai, Narayan, additional, Gupta, Aditya K., additional, Gvozdjakova, Anna, additional, Halabi, Ghazi, additional, Halmy, Ester, additional, Handjiev, Svetoslav, additional, Handjieva-Darlenska, Teodora, additional, Hilsabeck, Kyle D., additional, Horiuchi, Rie, additional, Hristova, Krasimira, additional, Hussein, Laila, additional, Isaza, Adrian, additional, Itharat, Arunporn, additional, Jaglan, Poonam, additional, Jarcuska, Peter, additional, Juneja, Lekh R., additional, Kalsum, Nurbani, additional, Karagiannis, Tom C., additional, Kartikey, Kumar, additional, Khan, Shairy, additional, Kucharská, Jarmila, additional, Kumar, Pramod, additional, Kuzeva, Aneliya, additional, Lee, Byong H., additional, Mahani, Mahani, additional, Maheshwari, Anuj, additional, Maurya, Kamlesh K., additional, McCord, D. Elizabeth, additional, Mesquita, Maria Fernanda de, additional, Mishra, Richa, additional, Modrzewski, Andrzej Frycz, additional, Mojto, Viliam, additional, Mojtová, Mária, additional, Nakajou, Masanori, additional, Oh, Deog H., additional, Onsaard, Ekasit, additional, Pella, Daniel, additional, Pella, Dominic, additional, Pella, Dominik, additional, Phomkong, Wiriya, additional, Rao, Shantanav S., additional, Ray, Nancy B., additional, Saboo, Banshi, additional, Sah, Deepak, additional, Sengupta, Ratnabali, additional, Sharma, Jagdish P., additional, Shewale, Anand R., additional, Silva, Maria Leonor Tavares da, additional, Singh, Amrat K., additional, Singh, Garima, additional, Singh, Jaipaul, additional, Singh, Meenakshi, additional, Singh, Mukta, additional, Singh, Ram B., additional, Singh, Rana G., additional, Singh, Reema, additional, Singh, Vaishali, additional, Singhal, Shantanu, additional, Srivastav, Manushi, additional, Srivastav, Ratan, additional, Sulaeman, Ahmad, additional, Takahashi, Toru, additional, Takei, Norihiro, additional, Télessy, István G., additional, Tomar, Rukam S., additional, Tripathi, Abhishek D., additional, Uehara, Mari, additional, Upadhyay, Ratna, additional, Vančová, Oľga, additional, Vargova, Viola, additional, Verma, Narsingh, additional, Watanabe, Shaw, additional, Watson, Ronald R., additional, Wichansawakun, Sanit, additional, Wilczynska, Agnieszka, additional, Wilson, Douglas W., additional, Yadav, Poonam, additional, and Zandi, Peiman, additional

Published
2019
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42. Globalization of Diets and Risk of Noncommunicable Diseases

Author

Fedacko, Jan, primary, Takahashi, Toru, additional, Singh, Ram B., additional, Pella, Dominik, additional, Chibisov, Sergey, additional, Hristova, Krasimira, additional, Pella, Daniel, additional, Elkilany, Galal Nagib, additional, Tomar, Rukam S., additional, and Juneja, Lekh R., additional

Published
2019
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46. Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients

Author

Nissen, Steven E., primary, Lincoff, A. Michael, additional, Brennan, Danielle, additional, Ray, Kausik K., additional, Mason, Denise, additional, Kastelein, John J.P., additional, Thompson, Paul D., additional, Libby, Peter, additional, Cho, Leslie, additional, Plutzky, Jorge, additional, Bays, Harold E., additional, Moriarty, Patrick M., additional, Menon, Venu, additional, Grobbee, Diederick E., additional, Louie, Michael J., additional, Chen, Chien-Feng, additional, Li, Na, additional, Bloedon, LeAnne, additional, Robinson, Paula, additional, Horner, Maggie, additional, Sasiela, William J., additional, McCluskey, Jackie, additional, Davey, Deborah, additional, Fajardo-Campos, Pedro, additional, Petrovic, Predrag, additional, Fedacko, Jan, additional, Zmuda, Witold, additional, Lukyanov, Yury, additional, and Nicholls, Stephen J., additional

Published
2023
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48. List of Contributors

Author

Ambalam, Padma, primary, Arici, Elif, additional, Bat, Levent, additional, Beriain, María J., additional, Bonos, Eleftherios, additional, Chauhan, Anil K., additional, Christaki, Efterpi, additional, Conte-Junior, Carlos A., additional, Costa, Marion P., additional, De Meester, Fabien, additional, Deligeorgis, Stelios G., additional, Dini, Irene, additional, Doble, Mukesh, additional, Fabisiak, Anna, additional, Fedacko, Jan, additional, Florou-Paneri, Panagiota, additional, Frasao, Beatriz S., additional, Giannenas, Ilias, additional, Gómez, Inmaculada, additional, Gvozdjakova, Anna, additional, Hamed, Imen, additional, Hristova, Krasimira, additional, Ibáñez, Francisco C., additional, Itharat, Arunporn, additional, Jaarin, Kamsiah, additional, Jaworski, Mariusz, additional, Kalkan, Indrani, additional, Kamisah, Yusof, additional, Kompanowska-Jezierska, Elżbieta, additional, Masbah, Norliana, additional, Mishra, Sanjay, additional, Nisianakis, Pavlos, additional, Olszyński, Krzysztof H., additional, Onsaard, Ekasit, additional, Ordóñez, Ana I., additional, Özogul, Fatih, additional, Perri, Enzo, additional, Raman, Maya, additional, Rodrigues, Bruna L., additional, Rongai, Domenico, additional, Sabatini, Nadia, additional, Sarakatsianos, Ioannis, additional, Sarriés, M. Victoria, additional, Simitzis, Panagiotis E., additional, Singh, Meenakshi, additional, Singh, Ram B., additional, Singh, Ravi P., additional, Türkmen, Ayşe Sonay, additional, Takahashi, Toru, additional, Viswanathan, Gopalan, additional, and Wilson, Douglas W., additional

Published
2018
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49. Development of a Functional Food Security for Parents for Transgenerational Epigenetic Health Promotion and Disease Prevention Among Offspring

Author

Singh, Ram B., primary, Chauhan, Anil K., additional, Singh, Ravi P., additional, Singh, Meenakshi, additional, Mishra, Sanjay, additional, De Meester, Fabien, additional, Hristova, Krasimira, additional, Takahashi, Toru, additional, Fedacko, Jan, additional, Gvozdjakova, Anna, additional, Itharat, Arunporn, additional, Onsaard, Ekasit, additional, and Wilson, Douglas W., additional

Published
2018
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50. Effects of Molecular Hydrogen in the Pathophysiology and Management of Cardiovascular and Metabolic Diseases

Author

Singh, Ram B, primary, Fatima, Ghizal, additional, Fedacko, Jan, additional, Mojto, Villiam, additional, Sumbalová, Zuzana, additional, Tarnava, Alex, additional, Pokotilo, Oleg, additional, Nazarov, Eugeny I, additional, Lee, Kyu-Jae, additional, Ferenczyova, Kristina., additional, Vlkovlkova, Jana, additional, Kalocayova, Barbora, additional, Slezak, Jan, additional, and Kim, Cheol-Su, additional

Published
2023
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